| 8569- | Matr, | Matrine inhibits the metastatic properties of human cervical cancer cells via downregulating the p38 signaling pathway |
| - | vitro+vivo, | Cerv, | NA |
| 8570- | Matr, | Matrine suppresses invasion of castration-resistant prostate cancer cells by downregulating MMP-2/9 via NF-κB signaling pathway |
| - | vitro+vivo, | Pca, | DU145 | - | in-vitro, | Pca, | PC3 |
| 8571- | Matr, | Effect of Matrine on HPAC cell migration by down-regulating the expression of MT1-MMP via Wnt signaling |
| - | in-vitro, | PC, | Capan1 |
| 8572- | Matr, | Matrine induces mitochondrial apoptosis in cisplatin-resistant non-small cell lung cancer cells via suppression of β-catenin/survivin signaling |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H460 |
| 8573- | Matr, | Matrine effectively inhibits the proliferation of breast cancer cells through a mechanism related to the NF-κB signaling pathway |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | BT20 | - | in-vitro, | BC, | MDA-MB-231 |
| 8574- | Matr, | Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration |
| - | in-vitro, | Lung, | A549 | - | ex-vivo, | HCC, | SMMC-7721 cell |
| 8575- | Matr, | Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3 |
| - | in-vitro, | GC, | SGC-7901 |
| 8576- | Matr, | Matrine reduces the proliferation and invasion of colorectal cancer cells via reducing the activity of p38 signaling pathway |
| - | vitro+vivo, | CRC, | NA |
| 8577- | Matr, | Cisplatin, | Meta analysis of compound matrine injection combined with cisplatin chemotherapy for advanced gastric cancer |
| - | Review, | GC, | NA |
| 8539- | Matr, | Matrine ameliorates cognitive deficits via inhibition of microglia mediated neuroinflammation in an Alzheimer's disease mouse model |
| - | in-vivo, | AD, | NA |
| 8554- | Matr, | Matrine injection inhibits pancreatic cancer growth via modulating carbonic anhydrases- a network pharmacology-based study with in vitro validation |
| - | in-vitro, | PC, | Capan1 | - | in-vitro, | PC, | MIA PaCa-2 |
| 8526- | Matr, | A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine |
| - | Review, | Nor, | NA |
| 8527- | Matr, | Matrine Promotes Human Myeloid Leukemia Cells Apoptosis Through Warburg Effect Mediated by Hexokinase 2 |
| - | in-vitro, | AML, | K562 |
| 8528- | Matr, | Cisplatin, | Matrine targets Enolase 1 and regulates the glycolysis-lactylation axis to enhance cisplatin sensitivity in triple-negative breast cancer |
| - | vitro+vivo, | BC, | NA |
| 8529- | Matr, | Matrine targets β-catenin and blocks the formation of β-catenin/TCF7L2 complex to promote ferroptosis and inhibit metastasis in triple-negative breast cancer |
| - | in-vitro, | BC, | NA |
| 8530- | Matr, | Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition |
| - | in-vitro, | HCC, | NA |
| 8531- | Matr, | Matrine: A review of its pharmacology, pharmacokinetics, toxicity, clinical application and preparation researches |
| - | Review, | Nor, | NA |
| 8532- | Matr, | Matrine induction of reactive oxygen species activates p38 leading to caspase-dependent cell apoptosis in non-small cell lung cancer cells |
| - | in-vitro, | NSCLC, | NA |
| 8533- | Matr, | Matrine induces the apoptosis of lung cancer cells through downregulation of inhibitor of apoptosis proteins and the Akt signaling pathway |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | 95D |
| 8534- | Matr, | Matrine induces apoptosis and autophagy in human lung adenocarcinoma cells via upregulation of Cavin3 and suppression of PI3K/AKT pathway |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Nor, | MRC-5 |
| 8535- | Matr, | Matrine induces ferroptosis in cervical cancer through activation of piezo1 channel |
| - | in-vitro, | Cerv, | NA |
| 8536- | Matr, | Effect of matrine against breast cancer by downregulating the vascular endothelial growth factor via the Wnt/β-catenin pathway |
| - | vitro+vivo, | BC, | 4T1 | - | in-vitro, | BC, | MCF7 |
| 8537- | Matr, | Matrine restrains the development of colorectal cancer through regulating the AGRN/Wnt/β-catenin pathway |
| - | vitro+vivo, | CRC, | NA |
| 8538- | Matr, | Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling |
| - | in-vitro, | BC, | MDA-MB-231 | - | ex-vivo, | BC, | MDA-MB-231 |
| 8540- | Matr, | Matrine improves cognitive impairment and modulates the balance of Th17/Treg cytokines in a rat model of Aβ1-42-induced Alzheimer's disease |
| - | in-vivo, | AD, | NA |
| 8542- | Matr, | Matrine Suppresses Lung Cancer Progression via Dual Inhibition of CHEK1-Mediated DNA Damage Repair and PI3K/AKT Survival Signaling |
| - | vitro+vivo, | Lung, | A549 |
| 8555- | Matr, | Matrine Exerts Pharmacological Effects Through Multiple Signaling Pathways: A Comprehensive Review |
| - | Review, | Var, | NA |
| 8553- | Matr, | Research progress on the pharmacological effects of matrine |
| - | Review, | Nor, | NA |
| 8552- | Matr, | Matrine exerts its neuroprotective effects by modulating multiple neuronal pathways |
| - | Review, | AD, | NA |
| 8551- | Matr, | Research Progress of Natural Matrine Compounds and Synthetic Matrine Derivatives |
| - | Review, | Nor, | NA |
| 8550- | Matr, | Matrine improves the hepatic microenvironment and reverses epithelial-mesenchymal transition in hepatocellular carcinoma by inhibiting the Wnt-1/β-catenin signaling pathway |
| - | vitro+vivo, | Liver, | HUH7 |
| 8549- | Matr, | Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis |
| - | in-vitro, | Var, | NA |
| 8548- | Matr, | The DHCR7 is the key target of lipotoxic liver injury caused by matrine through abnormal activation of the cholesterol synthesis pathway |
| - | in-vitro, | LiverDam, | NA |
| 8546- | Matr, | Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice |
| - | in-vivo, | Stroke, | NA |
| 8545- | Matr, | Matrine enhances RLS3-induced ferroptosis at non-toxic doses in acute myeloid leukemia cells with MLL rearrangement |
| - | in-vitro, | AML, | MV411 | - | in-vitro, | ALL, | MOLM-13 |
| 8544- | Matr, | Matrine in Liver Diseases: Mechanistic Insights and Therapeutic Potential |
| - | Review, | BC, | NA |
| 8543- | Matr, | Mechanism of matrine inhibiting retinoblastoma cell growth by downregulating NR1D2 to regulate phosphorylation of the PI3K/AKT signaling pathway |
| - | in-vitro, | RPE/RB, | Y79 |
| 8547- | Matr, | Matrine in cancer therapy: antitumor mechanisms and nano-delivery strategies |
| - | Review, | Var, | NA |
| 8541- | Matr, | Matrine induces ferroptosis and suppresses colorectal cancer through targeting the STAT3/SLC7A11 pathway |
| - | in-vivo, | CRC, | NA |
| 7824- | MBS, | IVT, | VT, | Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review |
| - | Review, | AD, | NA | - | Review, | Stroke, | NA | - | Review, | Park, | NA |
| 3902- | MCT, | Effects of Caprylic Triglyceride on Cognitive Performance and Cerebral Glucose Metabolism in Mild Alzheimer’s Disease: A Single-Case Observation |
| - | Case Report, | AD, | NA |
| 3903- | MCT, | Retrospective case studies of the efficacy of caprylic triglyceride in mild-to-moderate Alzheimer’s disease |
| - | Case Report, | AD, | NA |
| 3904- | MCT, | Retrospective cohort study of the efficacy of caprylic triglyceride in patients with mild-to-moderate alzheimer’s disease |
| - | Human, | AD, | NA |
| 3905- | MCT, | Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer's disease. A systematic review and meta-analysis of human studies |
| - | Review, | AD, | NA |
| 3901- | MCT, | Potential of Capric Acid in Neurological Disorders: An Overview |
| - | Review, | AD, | NA |
| - | in-vitro, | AD, | NA |
| 3899- | MCT, | COCONUT OIL: NON-ALTERNATIVE DRUG TREATMENT AGAINST ALZHEIMER´S DISEASE |
| - | Human, | AD, | NA |
| 3898- | MCT, | Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer's disease |
| - | Review, | AD, | NA |
| 3897- | MCT, | The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells |
| - | in-vitro, | AD, | NA |
| 3896- | MCT, | Improvement of Main Cognitive Functions in Patients with Alzheimer's Disease after Treatment with Coconut Oil Enriched Mediterranean Diet: A Pilot Study |
| - | Trial, | AD, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid