neuroP Cancer Research Results

neuroP, neuroprotective: Click to Expand ⟱
Source:
Type:
Neuroprotective refers to the ability of a substance, intervention, or strategy to preserve the structure and function of nerve cells (neurons) against injury or degeneration.
-While cancer and neurodegenerative processes might seem distinct, there is significant overlap in terms of treatment-related neurotoxicity, shared molecular mechanisms, and the potential for therapies that provide neuroprotection during cancer treatment.


Scientific Papers found: Click to Expand⟱
4862- Uro,    Neuroprotective effect of Urolithin A via downregulating VDAC1-mediated autophagy in Alzheimer's disease
- in-vivo, AD, NA - in-vitro, Nor, PC12
*cognitive↑, *p‑PI3K↓, *p‑Akt↓, *AMPK↑, *VDAC1↓, *neuroP↑, *PARK2↑, *PTEN↑, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p62↓, *Aβ↓, *Apoptosis↓,
4860- Uro,    Urolithins–gut Microbial Metabolites with Potential Health Benefits
- Review, Nor, NA - Review, AD, NA - Review, Park, NA
*ROS↓, *Inflam↓, TumCG↓, *neuroP↑, *cardioP↑, *LDL↓, *BioAv↝, *BioAv↓, *BioAv↑, *SIRT1↑, *mTOR↑, *BDNF↑, *cognitive↑,
4870- Uro,    Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
- in-vivo, AD, NA
*cognitive↑, *Apoptosis↓, *neuroP↑, *Aβ↓, *AMPK↑, *NF-kB↓, *MAPK↓, *BACE↑, *neuroG↑, *Inflam↓, *memory↑,
4872- Uro,    Urolithin A exhibits a neuroprotective effect against Alzheimer's disease by inhibiting DYRK1A activity
- in-vitro, AD, HEK293
*DYRK1A↓, *antiOx↑, *Inflam↓, *neuroP↑, *memory↑, *p‑tau↓, *Aβ↓, *neuroP↑,
4875- Uro,    Impact of the Natural Compound Urolithin A on Health, Disease, and Aging
- Review, AD, NA - Review, Stroke, NA - Review, ostP, NA - Review, IBD, NA
*MitoP↓, *Strength↑, *PINK1↑, *PARK2↑, *Inflam↓, *COX2↓, *IL1β↓, *IL6↓, *TNF-α↓, *OS↑, *cardioP↑, *memory↑, *neuroG↑, *neuroP↑, *Cartilage↑, *Inflam↓, *RenoP↑, *eff↑, *Dose↝, *Half-Life↑, *NRF2↑, *GutMicro↑,
4876- Uro,    Urolithin A in Health and Diseases: Prospects for Parkinson’s Disease Management
- Review, Park, NA - Review, AD, NA
*Inflam↓, *antiOx↓, *neuroP↑, *p‑tau↓, *Aβ↓, *eff↑, *BioAv↓, *BioAv↑, *GSH↑, *SOD↑, *lipid-P↓, *Catalase↑, *GSR↑, *GPx↑, *ROS↓, *NRF2↑, *GutMicro↑, *Risk↓, *BBB↓, *NLRP3↓, *MAOA↓,
4877- Uro,    Urolithin-A Derivative UAS03 Improves Cognitive Deficits and Memory by Activating Nrf2 Pathways to Alleviate Oxidative Stress and Neuroinflammation
- in-vivo, AD, NA
*cognitive↑, *memory↑, *neuroP↑, *NRF2↑, *ROS↓, *Inflam↓, *IL1β↓, *TNF-α↓, *COX2↓,
4879- Uro,    Neuroprotective Effect of Urolithin A against Cerebellum Changes in Streptozotocin-Induced Alzheimer’s Disease Rat Model
- in-vitro, AD, NA
*neuroP↑,
4880- Uro,    Urolithins: A Prospective Alternative against Brain Aging
- Review, AD, NA
*cognitive↑, *memory↑, *antiOx↑, *BBB↑, *ROS↓, *lipid-P↓, *Catalase↑, *SOD↑, *GSR↑, *GPx↑, *CREB↑, *BDNF↑, *neuroP↑, *Inflam↓, *MitoP↑, *Aβ↓, *tau↓, *NLRP3↓, *SIRT1↑, *SIRT3↑,
4833- Uro,    Unveiling the potential of Urolithin A in Cancer Therapy: Mechanistic Insights to Future Perspectives of Nanomedicine
- Review, Var, NA - Review, AD, NA - Review, IBD, NA
BioAv↝, TumAuto↝, TumCG↓, TumMeta↓, ChemoSen↑, Imm↑, RadioS↑, BioAv↑, other↝, eff↓, *antiOx↓, *Inflam↓, AntiCan↓, AntiAge↑, chemoP↑, *neuroP↑, *ROS↓, *cognitive↑, *lipid-P↓, *cardioP↑, *TNF-α↓, *IL6↓, GutMicro↑, TumCCA↑, Apoptosis↑, angioG↓, NF-kB↓, PI3K↓, Akt↓, Casp↑, survivin↓, TumCP↓, cycD1/CCND1↓, cMyc↑, BAX↑, Bcl-2↓, COX2↓, P53↑, p38↑, *ROS↓, *SOD↑, *GPx↑, SIRT1↑, FOXO1↑, eff↑, ChemoSen↑,
4858- Uro,    The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent
- in-vitro, Nor, NA
*ROS?, *neuroP↑, *lipid-P↓, *Catalase↑, *SOD↑, *GPx↑, *GSR↑, *monoA↓, *tyrosinase↓,
4313- VitA,RetA,    Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
- Review, AD, NA
*neuroP↑, memory↑, *Inflam↓, *neuroG↑, *cognitive↑, *Aβ↓, p‑tau↓, *BACE↓,
4311- VitB1/Thiamine,    Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy
- in-vivo, AD, NA
*Aβ↓, *p‑tau↓, *ROS↓, *cognitive↑, *OS↑, *Mood↑, *neuroP↑, *Inflam↓, *NRF2↑, *PGC-1α↑, *AGEs↓, *4-HNE↓, *NQO1↑, *COX2↓, *TNF-α↓, *IL1β↓, *NF-kB↓, *GSK‐3β↓,
4050- VitB12,  VitD3,  VitE,    Nutrient intake, nutritional status, and cognitive function with aging
- Review, AD, NA
neuroP↑,
4037- VitB12,  FA,    Mechanistic Link between Vitamin B12 and Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *ROS↓, *GSH↑, *Inflam↓, *IL6↓, *TNF-α↓, *other↑, *other↑, *other↑, *Aβ↓, *memory↑, *p‑tau↓, *APP↓, *BACE↓, *ATP↑, *neuroP↑,
4054- VitB12,  VitB6,  FA,    Role of B vitamins in modulating homocysteine and metabolic pathways linked to brain atrophy: Metabolomics insights from the VITACOG trial
- Study, AD, NA
*homoC↓, *neuroP↑, *cognitive↑,
4040- VitB12,  FA,    Role of vitamin B12 and folic acid in treatment of Alzheimer’s disease: a meta-analysis of randomized control trials
- Review, AD, NA
*memory↑, *neuroP↑, *cognitive↑, *QoL∅,
4031- VitB3,    Nicotinamide Riboside-The Current State of Research and Therapeutic Uses
- Review, NA, NA
*cardioP↑, *neuroP↑, *NAD↑, *SIRT1↑, *NADPH↑, *ROS↓, *IL2↓, *IL5↓, *IL6↓, *TNF-α↓, *Inflam↓, *BioAv↝, *BioAv↑,
4334- VitB5,    Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model
- in-vivo, AD, NA
*neuroP↑, *motorD↑, *MMP↑, *OCR↑,
4330- VitB5,    Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: Alleviation by pantethine
- in-vivo, AD, NA
*neuroP↑, *Inflam↓, *ATP↑, *G6PD↑, *NADPH↑, *IL1β↓, *other↝,
4329- VitB5,    Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer's Disease Pathogenesis in a Transgenic Mouse Model
- in-vivo, AD, NA
*Aβ↓, *Mood↑, *neuroP↑, *Inflam↓, *TNF-α↓, *BBB↝, *other↝, *Dose↝,
4326- VitB5,    Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington’s Disease
- in-vivo, HD, NA
*Risk↓, *neuroP↑, *other?, *Ach↑, *other↝, *eff↓, *other↝,
4323- VitB5,    Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer's disease
- Study, AD, NA
*Risk↓, *Acetyl-CoA↑, *Ach↑, *neuroP↑,
4052- VitB6,    B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study
- Study, AD, NA
*neuroP↑, *other↑, *other↑, *cognitive↑, *eff↝, *Risk↑, *other↑,
3102- VitC,    Two Faces of Vitamin C—Antioxidative and Pro-Oxidative Agent
- Review, Var, NA - Review, Stroke, NA
*radioP↑, *Dose↝, ROS↑, *neuroP↑, other↓, *ROS↓, *MMP↑,
3921- VitD3,  RES,    Vitamin D Combined with Resveratrol Prevents Cognitive Decline in SAMP8 Mice
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *BACE↓, *p‑tau↓, *p‑CREB↑, *p‑NF-kB↓, *neuroP↑,
4088- VitE,    Vitamin E and Alzheimer’s Disease—Is It Time for Personalized Medicine?
- Review, AD, NA
*antiOx↑, *neuroP↑, *Dose↓, *cognitive↑, *other↝,
4079- VitE,  VitC,    Effects of fruits and vegetables on levels of vitamins E and C in the brain and their association with cognitive performance
- Review, AD, NA
*neuroP↑, *antiOx↑, *Dose↝, *cognitive↑,
4087- VitE,    Vitamin E and Alzheimer's disease: what do we know so far?
- Review, AD, NA
*Risk↑, *Half-Life↑, *antiOx↑, *BioAv↑, *neuroP↑, *Inflam↑, *LDL↓, *cognitive↑,
4321- VitE,    Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
- Review, AD, NA
*ROS↓, *cardioP↑, *lipid-P↓, *cognitive↑, *neuroP↑, *Aβ↓, *NGF↑,
4322- VitK2,    Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
- Review, AD, NA
*memory↑, *cognitive↑, *Inflam↓, *Calcium↝, *Aβ↓, *ROS↓, *neuroP↑,
2281- VitK2,    The biological responses of vitamin K2: A comprehensive review
- Review, Var, NA
*ROS↓, *12LOX↓, *NF-kB↓, *BMD↑, *hepatoP↑, cycD1/CCND1↓, PKCδ↓, STAT3↓, ERK↑, MAPK↓, ROS↑, PI3K↝, Akt↝, Hif1a↝, *neuroP↑,
4084- Z,    Role of micronutrients in Alzheimer's disease: Review of available evidence
- Review, AD, NA
*neuroP↑, *cognitive↑, *AChE↓, *memory↑,

Showing Research Papers: 551 to 583 of 583
Prev Page 12 of 12

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 583

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

ROS↑, 2,  

Core Metabolism/Glycolysis(tgid=4)

cMyc↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5)

Akt↓, 1,   Akt↝, 1,   Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Casp↑, 1,   MAPK↓, 1,   p38↑, 1,   survivin↓, 1,  

Transcription & Epigenetics(tgid=7)

other↓, 1,   other↝, 1,  

Autophagy & Lysosomes(tgid=9)

TumAuto↝, 1,  

DNA Damage & Repair(tgid=10)

P53↑, 1,  

Cell Cycle & Senescence(tgid=11)

cycD1/CCND1↓, 2,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

ERK↑, 1,   FOXO1↑, 1,   PI3K↓, 1,   PI3K↝, 1,   STAT3↓, 1,   TumCG↓, 2,  

Migration(tgid=13)

PKCδ↓, 1,   TumCP↓, 1,   TumMeta↓, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   Hif1a↝, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2↓, 1,   Imm↑, 1,   NF-kB↓, 1,  

Synaptic & Neurotransmission(tgid=18)

p‑tau↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   BioAv↝, 1,   ChemoSen↑, 2,   eff↓, 1,   eff↑, 1,   RadioS↑, 1,  

Clinical Biomarkers(tgid=22)

GutMicro↑, 1,  

Functional Outcomes(tgid=23)

AntiAge↑, 1,   AntiCan↓, 1,   chemoP↑, 1,   memory↑, 1,   neuroP↑, 1,  
Total Targets: 45

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

4-HNE↓, 1,   antiOx↓, 2,   antiOx↑, 6,   Catalase↑, 3,   GPx↑, 4,   GSH↑, 2,   GSR↑, 3,   lipid-P↓, 5,   NQO1↑, 1,   NRF2↑, 4,   PARK2↑, 2,   ROS?, 1,   ROS↓, 13,   SIRT3↑, 1,   SOD↑, 4,   VDAC1↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

ATP↑, 2,   MMP↑, 2,   OCR↑, 1,   PGC-1α↑, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

12LOX↓, 1,   Acetyl-CoA↑, 1,   AMPK↑, 2,   CREB↑, 1,   p‑CREB↑, 1,   G6PD↑, 1,   homoC↓, 1,   LDL↓, 2,   NAD↑, 1,   NADPH↑, 2,   SIRT1↑, 3,  

Cell Death(tgid=5)

p‑Akt↓, 1,   Apoptosis↓, 2,   MAPK↓, 1,  

Transcription & Epigenetics(tgid=7)

Ach↑, 2,   other?, 1,   other↑, 6,   other↝, 5,  

Autophagy & Lysosomes(tgid=9)

DYRK1A↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   MitoP↓, 1,   MitoP↑, 1,   p62↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

GSK‐3β↓, 1,   mTOR↑, 1,   neuroG↑, 3,   p‑PI3K↓, 1,   PTEN↑, 1,   tyrosinase↓, 1,  

Migration(tgid=13)

APP↓, 1,   Cartilage↑, 1,  

Barriers & Transport(tgid=15)

BBB↓, 1,   BBB↑, 1,   BBB↝, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2↓, 3,   IL1β↓, 4,   IL2↓, 1,   IL5↓, 1,   IL6↓, 4,   Inflam↓, 16,   Inflam↑, 1,   NF-kB↓, 3,   p‑NF-kB↓, 1,   TNF-α↓, 7,  

Synaptic & Neurotransmission(tgid=18)

AChE↓, 1,   BDNF↑, 2,   MAOA↓, 1,   monoA↓, 1,   NGF↑, 1,   tau↓, 1,   p‑tau↓, 5,  

Protein Aggregation(tgid=19)

AGEs↓, 1,   Aβ↓, 12,   BACE↓, 3,   BACE↑, 1,   NLRP3↓, 2,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 2,   BioAv↑, 4,   BioAv↝, 2,   Dose↓, 1,   Dose↝, 4,   eff↓, 1,   eff↑, 2,   eff↝, 1,   Half-Life↑, 2,  

Clinical Biomarkers(tgid=22)

BMD↑, 1,   Calcium↝, 1,   GutMicro↑, 2,   IL6↓, 4,  

Functional Outcomes(tgid=23)

cardioP↑, 5,   cognitive↑, 18,   hepatoP↑, 1,   memory↑, 9,   Mood↑, 2,   motorD↑, 1,   neuroP↑, 33,   OS↑, 2,   QoL∅, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 3,   Risk↑, 2,   Strength↑, 1,  
Total Targets: 104

Scientific Paper Hit Count for: neuroP, neuroprotective
22 Resveratrol
21 Thymoquinone
20 Alpha-Lipoic-Acid
18 Magnetic Fields
18 Quercetin
16 Silymarin (Milk Thistle) silibinin
15 Urolithin
14 Curcumin
14 Chlorogenic acid
14 Hydrogen Gas
12 Rosmarinic acid
11 Baicalein
11 Lycopene
10 Ashwagandha(Withaferin A)
10 Carvacrol
10 Crocetin
9 Berberine
9 Bacopa monnieri
9 Chrysin
9 Ferulic acid
9 Honokiol
8 Moringa oleifera
8 Sulforaphane (mainly Broccoli)
7 Allicin (mainly Garlic)
7 Centella asiatica / Gotu kola → asiaticoside
7 Piperine
7 EGCG (Epigallocatechin Gallate)
7 Huperzine A/Huperzia serrata
7 Taurine
6 Apigenin (mainly Parsley)
6 Selenium NanoParticles
6 Cysteamine
6 Eugenol
6 Fisetin
6 Ginseng
6 Mushroom Lion’s Mane
6 Phenylbutyrate
6 Silicic Acid
5 Astaxanthin
5 Beta-Caryophyllene
5 Vitamin C (Ascorbic Acid)
5 α-Bisabolol / Chamomile oil
5 Capsaicin
5 Luteolin
5 Piperlongumine
5 Shankhpushpi
5 Shikonin
5 Vitamin E
5 Vitamin B5,Pantothenic Acid
4 Boron
4 Boswellia (frankincense)
4 Carnosic acid
4 Carnosine
4 Propolis -bee glue
4 Folic Acid, Vit B9
4 Shilajit/Fulvic Acid
4 Melatonin
4 Magnetic Field Rotating
4 Pterostilbene
4 Vitamin B12
3 Anthocyanins
3 Artemisinin
3 Biochanin A
3 Betulinic acid
3 Vitamin B6,pyridoxine
3 Caffeic acid
3 Exercise
3 Celastrol
3 Cichoric acid / Chicoric acid
3 Cinnamon
3 Coenzyme Q10
3 diet Short Term Fasting
3 Methylene blue
3 Magnolol
3 nicotinamide adenine dinucleotide
3 Rutin
3 Selenite (Sodium)
3 Ursolic acid
2 1,8-Cineole
2 Anethole/trans-Anethole
2 Baicalin
2 beta-carotene(VitA)
2 borneol
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Thymol-Thymus vulgaris
2 Chlorophyllin
2 Choline
2 Hydroxycinnamic-acid
2 Calorie Restriction Mimetics
2 Spermidine
2 Cucurbitacin
2 Metformin
2 D-limonene
2 Dandelion Root
2 Ellagic acid
2 Emodin
2 Ginkgo biloba
2 Geraniol
2 EMF
2 Naringin
2 Phosphatidylserine
2 Chemotherapy
2 Vitamin D3
2 Vitamin K2
1 Astragalus
1 alpha Linolenic acid
1 Aluminum
1 Fennel Oil/Foeniculum vulgare
1 doxorubicin
1 xanthohumol
1 Butyrate
1 Paclitaxel
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chitosan
1 Selenium
1 Carica papaya leaf extract
1 Aspirin
1 Carvone
1 Silver-NanoParticles
1 Dichloroacetate
1 Bortezomib
1 Diclofenac
1 Date Fruit Extract
1 diet Methionine-Restricted Diet
1 diet FMD Fasting Mimicking Diet
1 Eurycomanone
1 Germacranolide
1 MCToil
1 Methylsulfonylmethane
1 Nimbolide
1 Psoralidin
1 Salvia officinalis
1 Aromatherapy
1 Sesame seeds and Oil
1 Anti-oxidants
1 Aflavin-3,3′-digallate
1 Turmerones
1 Vitamin A, Retinoic Acid
1 Vitamin B1/Thiamine
1 Vitamin B3,Niacin
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1105  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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