BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
Scientific Papers found: Click to Expand⟱
8056- KAE,    Kaempferol: advances in biosynthesis, molecular mechanisms, and therapeutic applications
- Review, Var, NA - Review, Diabetic, NA
*antiOx↑, *ROS↓, *NRF2↑, *Inflam↓, *NF-kB↓, *MAPK↓, *STAT↓, *AntiDiabetic↑, *AMPK↑, *IRes↑, Apoptosis↑, TumCCA↑, TumMeta↓, PI3K↓, Akt↓, Wnt↓, β-catenin/ZEB1↓, *AntiBio↑, *hepatoP↑, *SIRT1↝, *BioAv↓,
9001- L-Theanine,    Kinetics of L-theanine uptake and metabolism in healthy participants are comparable after ingestion of L-theanine via capsules and green tea
- Human, Nor, NA
*Dose↝, *BioAv↑, *BioAv↝, *BioAv↝,
8174- Lap,    Lapatinib: a dual inhibitor of human epidermal growth factor receptor tyrosine kinases
- in-vitro, Var, NA
EGFR↓, HER2/EBBR2↓, BioAv↝, Synergy↑, Dose↝,
8172- Lap,    Administration of Lapatinib with Food Increases Its Plasma Concentration in Chinese Patients with Metastatic Breast Cancer: A Prospective Phase II Study
- Trial, BC, NA
BioAv↑, eff↑,
8171- Lap,    Effects of food on the relative bioavailability of lapatinib in cancer patients
- Trial, Var, NA
BioAv↝, Dose↝,
8163- LapC,    Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis
- in-vivo, Arthritis, NA
*DHODH↓, *Imm↓, AntiArt↑, antiPs↑, BioAv↝,
8166- LapC,    Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model
- vitro+vivo, BC, NA
BioAv↓, *toxicity↑, eff↑,
8215- LCA,    Determination of licochalcone A in rat plasma by UPLC–MS/MS and its pharmacokinetics
- in-vivo, Nor, NA
*BioAv↓,
8218- LCA,    Advances in Pharmacological Activities and Drug Delivery Systems of Licochalcone A
- Review, Nor, NA
*Inflam↓, *antiOx↑, *AntiTum↑, *hepatoP↑, *Bacteria↓, AntiCan↑, BioAv↓, BioAv↑,
8219- LCA,    Licochalcone A Ameliorates Cognitive Dysfunction in an Alzheimer's Disease Model by Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis
- in-vivo, AD, NA
*Dose↝, *cognitive↑, *Aβ↓, *ER Stress↓, *BioAv↑, *toxicity↓, *PERK↓, *eIF2α↓, *ATF4↓, *CHOP/DDIT3↓, *NRF2↑,
8240- LE,    Licorice flavonoids nanoparticles prepared by liquid antisolvent re-crystallization exhibit higher oral bioavailability and antioxidant activity in rat
- in-vivo, Nor, NA
*BioAv↑,
8271- LE,    Pharmacokinetic profile of glycyrrhizin in healthy volunteers by a new high-performance liquid chromatographic method
- Human, Nor, NA
*Dose↝, *BioAv↝,
8278- LE,    Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology
- Review, Var, NA
*Ingr↝, *AntiCan↑, *AntiDiabetic↑, *AntiBio↑, *Inflam↓, *antiAll↑, *hepatoP↑, *cough?, *SoreThr?, *toxicity↝, *cardioP↑, *BioAv↝, *PGE2↓, *COX2/PTGS2↓, *AntiAg↑, *ROS↓, *NLRP3↓, *NF-kB↓, *AP-1↓, TumCCA↑, Apoptosis↑, TumMeta↑, *Dose↝, *Dose↝, Ingr↝, TumAuto↑, LC3II↑, PI3K↓, Akt↓, mTOR↓, *cognitive↑, *BloodF↑, ChemoSen↑, ROS↓, *chemoP↑, ROS↑, tumCV↓, MMP↓, *AntiBio↑, *toxicity↝,
1794- LEC,    Effects of abomasal infusion of soybean or sunflower lecithin on nutrient digestibility and milk production in lactating dairy cows
- in-vivo, Nor, NA
*BioAv↑, *other↑,
1795- LEC,  Chit,    Self-assembled lecithin-chitosan nanoparticles improve the oral bioavailability and alter the pharmacokinetics of raloxifene
- in-vivo, Nor, NA
Synergy↑, BioAv↑,
1796- LEC,    A comprehensive review on pleiotropic effects and therapeutic potential of soy lecithin
- Review, Var, NA
BioAv↑, antiOx↑, LDL↓, memory↑,
8145- LF,    Neuroprotective Effects of Lactoferrin in Alzheimer's and Parkinson's Diseases: A Narrative Review
- Review, AD, NA - Review, Park, NA
*AntiBio↑, *Imm↑, *AntiCan↑, *neuroP↑, *BBB↑, *APOE4↓, *ROS↓, *Inflam↓, *Apoptosis↓, *Learn↑, *memory↑, *ADAM10↑, *PSEN1/PS1↑, *cl‑APP↑, *BACE/β-secretase↓, *cognitive↑, *MDA↓, *IL6↓, *TNF-α↓, *neuroP↑, *Dose↝, *IronCh↑, *SOD↑, *BioAv↝,
8136- LF,    Oral fate and stabilization technologies of lactoferrin: a systematic review
- Review, Nor, NA
*BioAv↓, *BioAv↓,
8135- LF,    Lactoferrin-A Regulator of Iron Homeostasis and Its Implications in Cancer
- Review, Var, NA - Review, AD, NA
IronCh↑, ROS↓, Imm↑, Inflam↓, *BBB↑, Iron↝, *Fenton↓, *ROS↓, *TAC↑, *SOD↑, *GPx↑, *GSH↑, *TBARS↓, *PTEN↓, *tau↓, *MAPK↓, *Aβ42↓, *Apoptosis↓, *Casp3↓, *Akt↑, *GutMicro↑, *Sepsis↓, *anemia↓, *IL6↓, *FPN↑, *TfR1/CD71↑, *Ferritin↓, *HemoG↑, *RBC↑, *eff↑, *BioAv↓, *BioAv↑, *BioAv↝, *ChemoSen↑, *BioAv↑, Ferroptosis↑,
8137- LF,    Lactoferrin delivery systems: approaches for its more effective use
- Review, IBD, NA
*Imm↑, *BioAv↓, *BioAv↑,
8193- LGE,    Targets and pathways involved in the antitumor activity of citral and its stereo-isomers
- Review, Var, NA
TumCP↓, Apoptosis↑, ROS↑, DNAdam↑, MARK4↓, ALDH1A3↓, CSCs↓, chemoR↓, BioAv↓, selectivity↝,
8200- LGE,    Chemical Properties and Therapeutic Potential of Citral, a Monoterpene Isolated from Lemongrass
- Review, Var, NA
*AntiBio↑, *antiOx↑, *AntiCan↑, *AntiDiabetic↑, *Inflam↓, Dose↝, BioAv↝,
8292- lign,    Anticancer potential of flaxseed lignans, their metabolites and synthetic counterparts in relation with molecular targets: current challenges and future perspectives
- Review, Var, NA
*BioAv↝, chemoPv↑, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, *AntiDiabetic↑, *antiOx↑, *AntiCan↑, *Inflam↓, *cardioP↑, TumCCA↑, PSA↓, miR-106b↓, IGF-1↓, ERK↓, Akt↓, Bcl-2↓, p‑FAK↓, radioP↑, P-gp/ABCB1↓, ChemoSen↑, MMP↓, ROS↑, BioAv↓, *toxicity↓, chemoP↑,
8295- lign,    Distribution, biosynthesis and therapeutic potential of lignans
- Review, Var, NA
*Ingr?, *BioAv↝, *antiOx↑, *AntiCan↑, *Inflam↓, *other?, Dose↝, AntiTum↑, pS2/TFF1↓, Bcl-2↓, IGF-1R↓, *radioP↑, *HO-1↑, GSTM1↑, NQO1↑, ChemoSen↑, *AntiDiabetic↑, *glucose↓, *GSH↑, *SOD↑, *MDA↓, *NO↓, *Bacteria↓, *AntiFungal↑,
8314- lign,    Reduction in Ki-67 in Benign Breast Tissue of High Risk Women with the Lignan Secoisolariciresinol Diglycoside (SDG)
- Trial, BC, NA
Dose↝, ENL↑, Ki-67↓, BioAv↑,
8297- lign,    Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside
- Trial, Nor, NA
*Dose?, *Half-Life↝, *Half-Life↝, *BioAv↝,
8329- LIN,    Microglial-targeting induced by intranasal linalool during neurological protection postischemia
- in-vivo, Stroke, NA - in-vivo, AD, NA
*Stroke↓, *BioAv↑, *neuroP↑, *motorD↑, *Learn↑, *COX2/PTGS2↓, *IL1β↓, *NRF2↑, *Dose↝, *cognitive↑,
8326- LIN,    Linalool in cancer pharmacology: pharmacokinetic limitations and preclinical cytotoxic evidence for translational development
- Review, Var, NA
Dose↝, *BioAv↓, BioAv↝, tumCV↓, compI↓, compII↓, ROS↑, ATP↓, GSH↓, mtDam↑, Casp↑, NF-kB↓, MMP↓, TumCCA↑, PI3K↓, Akt↓, angioG↓, CD31/PECAM-1↓, Ki-67↓,
8323- LIN,  doxoR,    Efficacy of Combination Therapy with Linalool and Doxorubicin Encapsulated by Liposomes as a Two-in-One Hybrid Carrier System for Epithelial Ovarian Carcinoma
- vitro+vivo, Ovarian, NA
ChemoSen↑, TumCG↓, Ki-67↓, CD31/PECAM-1↓, Casp3↑, *toxicity↓, chemoP↑, *BioAv↓, EPR↑,
8382- LT,    Luteolin as a dietary flavonoid for brain health: modulating neuroinflammation and cognitive decline in neurodegenerative disorders
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *antiOx↑, *NF-kB↓, *NRF2↑, *BDNF↑, *cognitive↑, *motorD↑, *BBB↑, *BioAv↓, *NO↓, *ROS↓, *NRF2↑, *ARE↑, *MMP↑, *BDNF↑, *Learn↑, *memory↑, *cognitive↑, *p‑JNK↓, *GFAP↓, *AIF1/Iba-1↓, *TNF-α↓, *IL1β↓, *BAX↓, *COX2/PTGS2↓, *BACE/β-secretase↓, *Aβ42↓, *PSD95↑, *SNAP25↑, *lipid-P↓, *GSTs↓, *GSH↑, *SOD↓, *Catalase↓, *AChE↓, *Casp3↓, *Casp9↓,
8375- LT,    Luteolin, a flavone ingredient: Anticancer mechanisms, combined medication strategy, pharmacokinetics, clinical trials, and pharmaceutical researches
- Review, Var, NA
TumCP↓, TumCI↓, Apoptosis↑, TumCCA↑, Inflam↓, Ferroptosis↑, Pyro↑, ChemoSen↑, chemoP↑, *BioAv↓, OATPs↓,
8379- LT,    Luteolin and neuroinflammation: a multi-target therapeutic strategy for central nervous system disorders
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*neuroP↑, *Inflam↓, *ROS↓, *Apoptosis↓, *BioAv↓, *BBB∅, Ferroptosis↑, ROS↑, Iron↑, lipid-P↑, MDA↑, GSH↓, GPx4↓, *Aβ↓, *memory↑, *neuroG↑, *NRF2↑, *NLRP3↓, *ROS↓, JAK2↓, STAT3↓, PD-L1↓, Perforin↝, GranB/GZMB↝, hepatoP↑, *Learn↑, *TNF-α↓, *IL1β↓, *IL6↓, *NO↓, *COX2/PTGS2↓, *iNOS↓, *ER Stress↓, *GRP78/BiP↓, *IRE1↓, *cognitive↑, *BAX↓, *Bcl-2↓, *Casp3↓, *PSD95↑, *SNAP25↑, *JNK↓, *eff↑, *mtDam↓, *MMP↑, *Stroke↓, *TJ↑, *MMP9↓, *BBB∅, *NeuroI↓,
8377- LT,    Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases
- Review, Asthma, NA
*PI3K↑, *Akt↑, *Inflam↓, *ROS↓, *BioAv↓, *RenoP↑, *cardioP↑, *neuroP↑, *antiAll↑, *AntiDiabetic↑, *hepatoP↑, *AntiThr↑, *toxicity↓, *IL10↓, *Sepsis↓, *TNF-α↓, *ROS↓, *GSH↑, *Catalase↑, *SOD↑, *MDA↓, *lipid-P↓, *IL4↓, *IL5↓, *PGE2↓, *PI3K↑, *Akt↑, *mTOR↑, *Beclin-1/ATG6↓, *Mucositis↓, *PLA2↓, STAT3↓, PD-L1↓, miR-34a↓, Casp3↑, Casp9↑, Bcl-2↓, BAX↑, Bax:Bcl2↑, Apoptosis↑, ROS↑, EMT↓, E-cadherin↓, DR5↑, LIMK1↓, Pain↓,
8384- LT,    Current situation and research progress of luteolin in the treatment of gastrointestinal malignant tumors
- Review, GC, NA
Apoptosis↑, TumAuto↑, TumCCA↑, EMT↓, *ROS↓, *antiOx↑, ROS↑, P53↑, LC3II↑, Beclin-1/ATG6↑, p‑MAP2K1/MEK1↓, p‑ERK↓, BAX↑, cl‑Casp3↑, Bcl-2↓, p‑MAPK↓, DNArepair↓, HMGB1↓, XRCC1↓, ERCC3↑, CycB/CCNB1↓, CDC2↓, p‑CHK1↑, TumCCA↑, TumCP?, Wnt↓, β-catenin/ZEB1↓, miR-384↑, PTN↓, MMP2↓, MMP3↓, MMP9↓, MMP16↓, Ferroptosis↑, GPx4↓, Synergy↑, Ki-67↓, GSH↓, ChemoSen↑, TumCP↓, TumCMig↓, TumCI↓, PI3K↓, Akt↓, mTOR↓, NF-kB↓, NOTCH↓, miR-139-5p↑, miR-34a↑, miR-422a↑, miR-107↑, miR-21↓, miR-155↓, miR-224↓, miR-340↓, E-cadherin↑, N-cadherin↓, Vim↓, HK1↓, FOXO1↓, compI↓, compIII↓, compV↓, ETC↓, BioAv↝,
8386- LT,    Luteolin induces apoptosis in Philadelphia chromosome-positive acute lymphoblastic leukemia cell by regulating the PI3K/AKT signaling pathway
- in-vitro, ALL, SUP-B15
tumCV↓, ROS↑, MMP↓, ATP↓, p‑PI3K↓, p‑Akt↓, p‑STAT3↓, Bcl-2↓, BAX↑, cl‑Casp3↑, cl‑Casp9↑, TumCP↓, eff↓, ChemoSen↑, FAK↓, Synergy↑, BioAv↓, BioAv↑,
8390- LT,    Luteolin in Inflammatory Bowel Disease and Colorectal Cancer: A Disease Continuum Perspective
- Review, IBD, NA - Review, CRC, NA
*Diff↝, *Inflam↓, *ROS↓, *GutMicro↑, *IBI↑, TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, *BioAv↑, *iNOS↓, *TNF-α↓, *IL6↓, *MDA↓, *lipid-P↓, *antiOx↑, *NRF2↑, *HO-1↑, *NQO1↑, *SOD↑, *Catalase↑, *5HT↓, *TPH1↓, *MAPK↓, *ERK↓, *Inflam↓, cycD1/CCND1↓, CDK4↓, TumCCA↑, Casp3↑, Casp9↑, PI3K↓, Akt↓, p‑Akt↓, p‑mTOR↓, E-cadherin↑, N-cadherin↓, Vim↓,
8398- LT,    Luteolin: Nature's promising warrior against Alzheimer's and Parkinson's disease
- Review, AD, NA - Review, Park, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *AntiCan↑, *hepatoP↑, *neuroP↑, *cardioP↑, *neuroG↑, *BBB↑, *ROS↓, *AChE↓, *p‑T-cadherin↓, *Aβ↓, *memory↑, *TNF-α↓, *IL1β↓, *MCP1/CCL2↓, *RANTES↓, *BioAv↑, *Half-Life↝, *toxicity↓, *BACE/β-secretase↓, *Aβ42↓, *COX2/PTGS2↓, *Bcl-2↓, *Casp3↓, *BAX↓, *GSTs↓, *lipid-P↓, *Casp3↓, *Casp9↓, *memory↑, *GSK‐3β↓, *ChAT↑, *SOD↑, *GPx↑, *MDA↓, *ER Stress↓, *GRP78/BiP↓, *NRF2↑, *motorD↑, *antiAll↑,
2910- LT,  FA,    Folic acid-modified ROS-responsive nanoparticles encapsulating luteolin for targeted breast cancer treatment
- in-vitro, BC, 4T1 - in-vivo, NA, NA
BioAv↓, BioAv↑, eff↑, tumCV↓, e-H2O2↓, i-H2O2∅,
2912- LT,    Luteolin: a flavonoid with a multifaceted anticancer potential
- Review, Var, NA
ROS↑, TumCCA↑, TumCP↓, angioG↓, ER Stress↑, mtDam↑, PERK↑, ATF4↑, eIF2α↑, cl‑Casp12↑, EMT↓, E-cadherin↑, N-cadherin↓, Vim↓, *neuroP↑, NF-kB↓, PI3K↓, Akt↑, XIAP↓, MMP↓, Ca+2↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, Cyt‑c↑, IronCh↑, SOD↓, *ROS↓, *LDHA↑, *SOD↑, *GSH↑, *BioAv↓, Telomerase↓, cMyc↓, hTERT/TERT↓, DR5↑, Fas↑, FADD↑, BAD↑, BOK↑, BID↑, NAIP↓, Mcl-1↓, CDK2↓, CDK4↓, MAPK↓, AKT1↓, Akt2↓, *Beclin-1/ATG6↓, Hif1a↓, LC3II↑, Beclin-1/ATG6↑,
2914- LT,    Therapeutic Potential of Luteolin on Cancer
- Review, Var, NA
*antiOx↑, *IronCh↑, *toxicity↓, *BioAv↓, *BioAv↑, DNAdam↑, TumCP↓, DR5↑, P53↑, JNK↑, BAX↑, cl‑Casp3↑, cl‑Casp8↑, cl‑Casp9↑, cl‑PARP↑, survivin↓, cycD1/CCND1↓, CycB/CCNB1↓, CDC2↓, P21↑, angioG↓, MMP2↓, AEG1↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP9↓, CXCR4↓, PI3K↓, Akt↓, ERK↓, TumAuto↑, LC3B-II↑, EMT↓, E-cadherin↑, N-cadherin↓, Wnt↓, ROS↑, NICD↓, p‑GSK‐3β↓, iNOS↓, COX2/PTGS2↓, NRF2↑, Ca+2↑, ChemoSen↑, ChemoSen↓, IFN-γ↓, RadioS↑, MDM2↓, NOTCH1↓, AR↓, TIMP1↑, TIMP2↑, ER Stress↑, CDK2↓, Telomerase↓, p‑NF-kB↑, p‑cMyc↑, hTERT/TERT↓, RAS↓, YAP/TEAD↓, TAZ↓, NF-kB↓, NRF2↓, HO-1↓, MDR1↓,
2920- LT,    Formulation, characterization, in vitro and in vivo evaluations of self-nanoemulsifying drug delivery system of luteolin
- in-vitro, Nor, NA - in-vivo, Nor, NA
BioAv↑, eff↑,
2919- LT,    Luteolin as a potential therapeutic candidate for lung cancer: Emerging preclinical evidence
- Review, Var, NA
RadioS↑, ChemoSen↑, chemoP↑, *lipid-P↓, *Catalase↑, *SOD↑, *GPx↑, *GSTs↑, *GSH↑, *TNF-α↓, *IL1β↓, *Casp3↓, *IL10↑, NRF2↓, HO-1↓, NQO1↓, GSH↓, MET↓, p‑MET↓, p‑Akt↓, HGF/c-Met↓, NF-kB↓, Bcl-2↓, SOD2↓, Casp8↑, Casp3↑, PARP↑, MAPK↓, NLRP3↓, ASC↓, Casp1↓, IL6↓, IKKα↓, p‑p65↓, p‑p38↑, MMP2↓, ICAM-1↓, EGFR↑, p‑PI3K↓, E-cadherin↓, ZO-1↑, N-cadherin↓, CLDN1↓, β-catenin/ZEB1↓, Snail↓, Vim↑, ITGB1↓, FAK↓, p‑Src↓, Rac1↓, Cdc42↓, Rho↓, PCNA↓, Tyro3↓, AXL↓, CEA↓, NSE↓, SOD↓, Catalase↓, GPx↓, GSR↓, GSTs↓, GSH↓, VitE↓, VitC↓, CYP1A1↓, cFos↑, AR↓, AIF↑, p‑STAT6↓, p‑MDM2↓, NOTCH1↓, VEGF↓, H3↓, H4↓, HDAC↓, SIRT1↓, ROS↑, DR5↑, Cyt‑c↑, p‑JNK↑, PTEN↓, mTOR↓, CD34↓, FasL↑, Fas↑, XIAP↓, p‑eIF2α↑, CHOP/DDIT3↑, LC3II↑, PD-1↓, STAT3↓, IL2↑, EMT↓, cachexia↓, BioAv↑, *Half-Life↝, *eff↑,
2916- LT,    Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies
- Review, Var, NA - Review, AD, NA - Review, Park, NA
proCasp9↓, CDC2↓, CycB/CCNB1↓, Casp9↑, Casp3↑, Cyt‑c↑, cycA1/CCNA1↑, CDK2↓, APAF1↑, TumCCA↑, P53↑, BAX↑, VEGF↓, Bcl-2↓, Apoptosis↑, p‑Akt↓, p‑EGFR↓, p‑ERK↓, p‑STAT3↓, cardioP↑, Catalase↓, SOD↓, *BioAv↓, *antiOx↑, *ROS↓, *NO↓, *GSTs↑, *GSR↑, *SOD↑, *Catalase↑, *lipid-P↓, PI3K↓, Akt↓, CDK2↓, BNIP3↑, hTERT/TERT↓, DR5↑, Beclin-1/ATG6↑, TNF-α↓, NF-kB↓, IL1↓, IL6↓, EMT↓, FAK↓, E-cadherin↑, MDM2↓, NOTCH↓, MAPK↑, Vim↓, N-cadherin↓, Snail↓, MMP2↓, Twist↓, MMP9↓, ROS↑, MMP↓, *AChE↓, *MMP↑, *Aβ↓, *neuroP↑, Trx1↑, ROS↓, *NRF2↑, NRF2↓, *BBB↑, ChemoSen↑, GutMicro↑, *antiAll↑, *Mucositis↓, *TregCell↑, *Beclin-1/ATG6↓, *PI3K↑, *Akt↑, *mTOR↑,
4292- LT,    Luteolin for neurodegenerative diseases: a review
- Review, AD, NA - Review, Park, NA - Review, MS, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↝, *BBB↑, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL33↓, *NF-kB↓, *BACE/β-secretase↓, *ROS↓, *SOD↑, *HO-1↑, *NRF2↑, *Casp3↓, *Casp9↑, *Bax:Bcl2↓, *UPR↑, *GRP78/BiP↑, *Aβ↓, *GSK‐3β↓, *tau↓, *CREB↑, *ATP↑, *cognitive↑, *BloodF↑, *BDNF↑, *TrkB↑, *memory↑, *PPARγ↑, *Synergy↑,
8357- Lut,    Comparison of lutein bioavailability from vegetables and supplement
- Study, Nor, NA
*Dose↝, *BioAv↑, *eff↑,
8356- Lut,    Amount of fat in the diet affects bioavailability of lutein esters but not of alpha-carotene, beta-carotene, and vitamin E in humans
- Trial, Nor, NA
*BioAv↑, *Dose↝,
8343- Lut,    Association of Lutein with Cancer: A Systematic Review of the Lutein Effects on Cellular Processes Involved in Cancer Progression
- Review, Var, NA
*antiOx↑, *Inflam↓, Risk↓, AntiCan∅, Apoptosis↑, ROS↓, NRF2↓, Akt↓, ERK↓, NF-kB↓, Bcl-2↓, BAX↑, Casp3↑, DNAdam↑, ROS↓, P53↑, PCNA↓, cycD1/CCND1↓, TumCP↓, Hif1a↓, NOTCH↓, miR-590-3p↑, TumCMig↓, TumCI↓, TumMeta↓, TumCA↓, *BioAv↓,
3528- Lyco,    The Importance of Antioxidant Activity for the Health-Promoting Effect of Lycopene
- Review, Nor, NA - Review, AD, NA - Review, Park, NA
*antiOx↑, *ROS↓, *BioAv↝, *Half-Life↑, *BioAv↓, *BioAv↑, *cardioP↑, *neuroP↑, *H2O2↓, *VitC↑, *VitE↑, *GPx↑, *GSH↑, *MPO↓, *GSTs↓, *SOD↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL10↑, *MAPK↓, *Akt↓, *COX2/PTGS2↓, *TNF-α↓, *TGF-β1↑, *NO↓, *GSR↑, *NRF2↑, *HO-1↑, *TAC↑, *Inflam↓, *BBB↑, *neuroP↑, *memory↑,
3268- Lyco,    Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
- Review, AD, NA
*BioAv↓, *AntiCan↑, *ROCK1↓, *Ki-67↓, *ICAM-1↓, *cardioP↑, *antiOx↑, *NQO1↑, *HO-1↑, *TNF-α↓, *IL22↓, *NRF2↑, *NF-kB↓, *MDA↓, *Catalase↑, *SOD↑, *GSH↑, *cognitive↑, *tau↓, *hepatoP↑, *MMP2↑, *AST↓, *ALAT↓, *P450↑, *DNAdam↓, *ROS↓, *neuroP↑, *memory↑, *Ca+2↓, *Dose↝, *Dose↑, *Dose↝, *toxicity∅, PGE2↓, CDK2↓, CDK4↓, STAT3↓, NOX↓, NOX4↓, ROS↓, *SREBP1/SREBF1↓, *FASN↓, *ACC↓,
3260- Lyco,    Lycopene in human health
- Review, Nor, NA
*BioAv↝, *BioAv↓, *ROS⇅, *BioAv↝,

Showing Research Papers: 551 to 600 of 860
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 860

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 5,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 17,   ARE↓, 1,   Catalase↓, 7,   Catalase↑, 5,   Fenton↑, 4,   frataxin↑, 1,   GPx↓, 3,   GPx↑, 5,   GPx4↓, 11,   GPx4↑, 1,   GSH↓, 34,   GSH↑, 7,   GSH/GSSG↓, 1,   GSR↓, 2,   GSR↑, 1,   ox-GSSG↑, 1,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 4,   e-H2O2↓, 1,   i-H2O2∅, 1,   HO-1↓, 6,   HO-1↑, 10,   HO-2↓, 1,   Iron↑, 5,   Iron↝, 1,   i-Iron↑, 1,   c-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 8,   lipid-P↑, 15,   MDA↓, 3,   MDA↑, 5,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NOX4↑, 1,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 16,   NRF2↑, 23,   Prx↓, 1,   Prx4↑, 1,   Prx6↑, 1,   ox-PrxI↑, 1,   PrxII↓, 1,   PYCR1↓, 1,   ROS?, 1,   ROS↓, 28,   ROS↑, 236,   ROS⇅, 9,   ROS↝, 3,   i-ROS↓, 1,   i-ROS↑, 2,   mt-ROS↑, 1,   SOD↓, 9,   SOD↑, 8,   SOD1↓, 2,   SOD2↓, 4,   SOD2↑, 1,   Thiols↓, 2,   Trx↓, 2,   Trx1↑, 1,   TrxR↓, 8,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 5,   Tf↓, 1,   Tf↑, 1,   TfR1/CD71↑, 2,   Zn2+↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 2,   BCR-ABL↓, 1,   CDC2↓, 4,   CDC25↓, 5,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   compV↓, 1,   EGF↓, 2,   ETC↓, 3,   ETC↑, 1,   MFN2↑, 1,   mitResp↓, 2,   Mortalin↓, 1,   mtDam↓, 1,   mtDam↑, 16,   OCR↓, 2,   OCR↑, 3,   OXPHOS↓, 5,   OXPHOS↑, 3,   mt-OXPHOS↓, 2,   PDH↑, 2,   PGC-1α↑, 1,   PINK1↑, 1,   SDH↑, 1,   SIRT3↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 1,   5LO↓, 5,   ACLY↓, 2,   ACSL4↑, 1,   ALAT↓, 6,   ALAT↑, 1,   ALDOA↓, 1,   AMPK↑, 19,   AMPK↝, 1,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 18,   ATP↑, 1,   mt-ATP↓, 1,   CAIX/CA9↓, 1,   CAIX/CA9↑, 1,   CRM↝, 1,   ECAR↓, 3,   ECAR↝, 1,   ENO1↓, 2,   FASN↓, 5,   FDG↓, 1,   GAPDH↓, 2,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↓, 1,   GlucoseCon↓, 12,   GlutaM↓, 1,   GlutMet↓, 1,   Glycolysis↓, 36,   Glycolysis↝, 1,   GSK‐3β↓, 14,   GSK‐3β↑, 5,   p‑GSK‐3β↓, 1,   H2S↑, 1,   HK1↓, 1,   HK2↓, 18,   HMG-CoA↓, 1,   IDH1↓, 1,   lactateProd↓, 14,   lactateProd↑, 1,   LDHA↓, 3,   LDL↓, 4,   lipoGen↓, 1,   MCT4↓, 2,   NADH:NAD↓, 1,   NADPH↓, 4,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 8,   PDK3↑, 1,   PFK1↓, 1,   PKM2↓, 11,   SCD1↓, 1,   SIRT1↓, 8,   SIRT1↑, 8,   SIRT2↓, 1,   SIRT2↑, 1,   SREBP1/SREBF1↓, 1,   TCA↓, 2,   TCA↑, 1,   TCA↝, 1,   UGDH↓, 2,   Warburg↓, 11,  

Cell Death(tgid=5) ⓘ

AIF↑, 13,   APAF1↑, 4,   Apoptosis?, 1,   Apoptosis↓, 2,   Apoptosis↑, 190,   mt-Apoptosis↑, 2,   ASC↓, 1,   BAD↓, 2,   BAD↑, 4,   Bak↓, 1,   Bak↑, 6,   BAX↓, 3,   BAX↑, 84,   Bax:Bcl2↓, 1,   Bax:Bcl2↑, 20,   Bcl-2↓, 85,   Bcl-2↑, 4,   Bcl-xL↓, 20,   BID↓, 1,   BID↑, 3,   p‑BID↓, 1,   BIM↓, 1,   BIM↑, 4,   BNIP3↑, 1,   BNIP3↝, 1,   BOK↑, 1,   Casp↑, 39,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 3,   Casp12?, 1,   Casp12↑, 1,   cl‑Casp12↑, 1,   Casp3↓, 2,   Casp3↑, 101,   Casp3↝, 1,   cl‑Casp3↑, 13,   cl‑Casp3⇅, 1,   proCasp3↑, 1,   Casp6↑, 1,   Casp7↑, 14,   cl‑Casp7↑, 2,   Casp8↑, 23,   cl‑Casp8↑, 2,   proCasp8↑, 1,   pro‑Casp8↑, 1,   Casp9↓, 1,   Casp9↑, 61,   cl‑Casp9↑, 6,   proCasp9↓, 1,   cFLIP↓, 3,   Cyt‑c↓, 3,   Cyt‑c↑, 56,   Cyt‑c↝, 1,   Diablo↑, 3,   DR5↑, 19,   Endon↑, 1,   FADD↑, 5,   Fas↑, 11,   FasL↓, 1,   FasL↑, 6,   Ferroptosis↑, 20,   GranB/GZMB↓, 1,   GranB/GZMB↝, 1,   GSDME↑, 1,   IAP1↓, 4,   IAP2/BIRC3↓, 2,   IAP2/BIRC3↑, 1,   ICD↑, 1,   iNOS↓, 15,   Mcl-1↓, 18,   Mcl-1↑, 1,   p‑Mcl-1↓, 1,   MDM2↓, 8,   MDM2↑, 2,   p‑MDM2↓, 1,   MOMP↓, 1,   MOMP↑, 4,   NAIP↓, 1,   Necroptosis↑, 2,   necrosis↑, 4,   NOXA↑, 4,   p38↓, 2,   p38↑, 14,   p‑p38↓, 1,   p‑p38↑, 2,   Paraptosis↑, 1,   Perforin↝, 1,   pS2/TFF1↓, 1,   PUMA↓, 1,   PUMA↑, 5,   Pyro↑, 3,   RIP3↑, 1,   survivin↓, 37,   TRAIL↑, 2,   TRAIL⇅, 1,   TRAILR↑, 1,   TumCD↓, 2,   TumCD↑, 17,   XIAP↓, 20,   XIAP↑, 1,   YAP/TEAD↓, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 2,   Akt↓, 126,   Akt↑, 6,   p‑Akt↓, 31,   AKT1↓, 3,   Akt2↓, 1,   AMPKα↑, 1,   BRAF↓, 1,   CaMKII ↓, 1,   CIP2A↓, 1,   CK2↓, 2,   cMET↓, 3,   cSrc↓, 2,   DDIT4↑, 1,   DYRK1B↓, 1,   EF-1α↓, 1,   EGFR↓, 30,   EGFR↑, 2,   p‑EGFR↓, 1,   ERK↓, 42,   ERK↑, 5,   p‑ERK↓, 12,   FGFR1↓, 3,   FGFR2↓, 1,   FOXD3↑, 1,   HER2/EBBR2↓, 7,   HGF/c-Met↓, 3,   Hippo↑, 1,   IGF-1R↓, 3,   IGF-2R↑, 1,   IKKα↓, 3,   p‑IKKα↓, 1,   IκB↓, 1,   IκB↑, 1,   JAK↓, 5,   JAK1↓, 3,   JAK1↑, 1,   JAK2↓, 9,   p‑JAK2↓, 1,   JNK↓, 6,   JNK↑, 16,   p‑JNK↑, 2,   LIMK1↓, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 32,   MAPK↑, 13,   MAPK↝, 2,   p‑MAPK↓, 1,   MARK4↓, 2,   MEK↓, 3,   mTOR↓, 70,   mTOR⇅, 1,   mTOR↝, 2,   p‑mTOR↓, 6,   p‑p70S6↓, 1,   P70S6K↓, 2,   p‑P70S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 98,   PI3K↑, 3,   PI3K↝, 1,   p‑PI3K↓, 4,   p‑PI3K↑, 1,   PKA↓, 2,   PKCδ↓, 7,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 33,   Raf↓, 3,   c-Raf↓, 1,   RAS↓, 11,   RET↓, 1,   RIP1↑, 1,   SHP1↑, 1,   Sp1/3/4↓, 6,   Sp1/3/4↑, 1,   Src↓, 3,   p‑Src↓, 1,   STAT↓, 3,   STAT3↓, 65,   STAT3↑, 3,   p‑STAT3↓, 10,   p‑STAT3↑, 2,   STAT6↓, 3,   p‑STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↓, 1,   ATF4↑, 6,   ATF4↝, 1,   CBP↓, 2,   cJun↓, 3,   cJun↑, 1,   p‑cJun↑, 1,   cMyc↓, 34,   cMyc↑, 1,   p‑cMyc↑, 1,   DNMT1↓, 7,   DNMT3A↓, 2,   DNMTs↓, 7,   EZH2↓, 5,   FOXM1↓, 4,   FOXO1↓, 2,   FOXO1↑, 2,   FOXO3↓, 1,   FOXO3↑, 4,   FOXO3↝, 1,   FOXO4↑, 2,   H3↓, 2,   H3↑, 2,   ac‑H3↑, 1,   H4↓, 1,   H4↑, 2,   HATs↓, 4,   HATs↑, 4,   HDAC↓, 27,   HDAC1↓, 8,   HDAC10↓, 1,   HDAC2↓, 6,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC8↓, 2,   HES1↓, 1,   miR-106b↓, 2,   miR-107↑, 1,   miR-124-3p↓, 1,   miR-139-5p↑, 1,   miR-155↓, 2,   miR-19b↓, 2,   miR-200b↑, 1,   miR-203↑, 1,   miR-21↓, 7,   miR-218↑, 1,   miR-224↓, 1,   miR-25-5p↓, 1,   miR-27a-3p↓, 1,   miR-29b↓, 1,   miR-30a-5p↑, 1,   miR-339-5p↝, 1,   miR-340↓, 1,   miR-34a↓, 2,   miR-34a↑, 6,   miR-375↑, 1,   miR-384↑, 1,   miR-422a↑, 1,   miR-590-3p↑, 1,   MTA2↓, 1,   Myc↓, 5,   MYCN↓, 1,   OCT4↓, 9,   other↓, 2,   other↑, 8,   other↝, 40,   other∅, 1,   PhotoS↑, 3,   SD↑, 1,   sonoS↑, 1,   SOX2↓, 6,   SOX4↓, 2,   SOX4↑, 1,   SOX9?, 1,   tumCV?, 1,   tumCV↓, 25,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 15,   cl‑CHOP/DDIT3↑, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↓, 1,   eIF2α↑, 4,   p‑eIF2α↑, 2,   ER Stress↓, 1,   ER Stress↑, 34,   GRP78/BiP?, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 6,   GRP78/BiP↝, 1,   HSP27↝, 1,   HSP70/HSPA5↓, 2,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 12,   PERK↑, 8,   Proteasome↓, 1,   UPR↑, 6,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   ATG7↑, 2,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 8,   CTSK↓, 1,   LAMP1?, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B-II↑, 2,   LC3II↓, 2,   LC3II↑, 14,   p62↓, 5,   p62↑, 3,   PARK2↑, 1,   SESN2↑, 2,   TFEB↑, 1,   TumAuto↓, 2,   TumAuto↑, 38,   TumAuto⇅, 1,   TumAuto↝, 2,  

DNA Damage & Repair(tgid=10) ⓘ

APE1/APEX1↓, 1,   ATM?, 1,   ATM↑, 2,   BRCA1↓, 2,   p‑BRCA1↑, 1,   DFF45↓, 1,   DNAdam↓, 3,   DNAdam↑, 51,   DNAdamC↑, 1,   DNArepair↓, 3,   DNArepair↑, 1,   ERCC3↑, 1,   m-FAM72A↓, 1,   G9a↓, 1,   hTERT/TERT↓, 13,   MGMT↓, 2,   NKX3.1↓, 1,   p16↑, 2,   P53?, 1,   P53↓, 4,   P53↑, 72,   p‑P53↑, 1,   p53 Wildtype↓, 1,   p53 Wildtype↑, 1,   p53 Wildtype∅, 1,   p73↑, 1,   PARP↓, 1,   PARP↑, 19,   cl‑PARP↓, 2,   cl‑PARP↑, 49,   PARP1↑, 1,   PCNA↓, 17,   SIRT6↑, 1,   Telomerase↓, 16,   TOP1?, 1,   TOP1↓, 11,   TOP2↓, 6,   TOP2↑, 2,   TP53↑, 4,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↓, 1,   γH2AX↑, 3,   γH2AX↝, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 8,   CDK1↑, 5,   CDK2↓, 30,   CDK2↑, 1,   CDK4↓, 39,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 11,   CDK6↑, 1,   CDK7↓, 1,   CDK8↓, 1,   CDKN1C/p57↓, 1,   CDKN1C/p57↑, 1,   CHK1↓, 2,   p‑CHK1↑, 1,   Chk2↓, 2,   Cyc↓, 1,   cycA1/CCNA1↓, 3,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 21,   CycB/CCNB1↑, 4,   cycD1/CCND1↓, 54,   cycD1/CCND1↑, 2,   p‑cycD1/CCND1↓, 1,   CycD3↓, 1,   cycE/CCNE↓, 13,   E2Fs↓, 5,   E2Fs↑, 1,   Ki-67↓, 27,   mitA↑, 3,   p19↑, 1,   P21?, 1,   P21↓, 1,   P21↑, 42,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 16,   pRB↓, 1,   RB1↑, 1,   p‑RB1↓, 5,   Securin↓, 1,   TubPol↓, 1,   TumCCA↓, 6,   TumCCA↑, 169,   UBE2C↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 7,   ALDH1A1↓, 2,   ALDH1A3↓, 1,   Axin2↑, 1,   BMP7/OP1↓, 1,   BMPs↑, 2,   CD133↓, 3,   CD133↑, 1,   CD34↓, 1,   cFos↓, 4,   cFos↑, 1,   cMYB↓, 2,   CSCs?, 1,   CSCs↓, 43,   Diff↑, 2,   EIF4E↓, 1,   FGF↓, 3,   Gli↓, 2,   Gli1↓, 9,   HH↓, 10,   HH∅, 1,   HMGCR↓, 1,   IGF-1↓, 6,   IGFBP1↑, 1,   IGFBP3↑, 1,   JAG1↓, 1,   Ki-67↓, 27,   Let-7↑, 3,   LRP6↓, 1,   mTORC1↓, 5,   Nanog↓, 10,   Nestin↓, 2,   NICD↓, 1,   NOTCH↓, 16,   NOTCH1↓, 12,   NOTCH1↑, 4,   NOTCH3↓, 2,   p300↓, 2,   PTCH1↓, 1,   PTCH2↓, 1,   Shh↓, 8,   Smo↓, 3,   STAT1↓, 1,   TAZ↓, 1,   TumCG↓, 70,   TumCG↑, 3,   TumCP?, 1,   TumCP↓, 130,   TumCP↑, 5,   TumCP⇅, 1,   tyrosinase↓, 2,   Wnt↓, 41,   Wnt↝, 1,   Wnt/(β-catenin)↓, 2,   Zn2+↑, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   annexin II↓, 1,   AP-1↓, 10,   ASAP2↓, 1,   AXL↓, 1,   BACH1↓, 1,   CA↓, 1,   Ca+2↓, 3,   Ca+2↑, 18,   Ca+2↝, 2,   Cav1↓, 1,   Cdc42↓, 1,   Cdc42↑, 1,   CTNNB1↓, 1,   E-cadherin↓, 9,   E-cadherin↑, 30,   EMT↓, 64,   EMT↑, 1,   EpCAM↓, 2,   FAK↓, 11,   FAK↑, 1,   p‑FAK↓, 4,   fascin↓, 1,   Fibronectin↓, 1,   GLI2↓, 1,   hnRNPA1↓, 1,   ITGB1↓, 3,   ITGB3↓, 1,   ITGB6↓, 1,   KRAS↓, 2,   LAMs↓, 2,   MALAT1↓, 3,   MET↓, 1,   p‑MET↓, 1,   MMP-10↓, 1,   MMP1↓, 5,   MMP13↓, 4,   MMP15↓, 1,   MMP16↓, 1,   MMP2↓, 77,   MMP2↑, 1,   MMP3↓, 7,   MMP7↓, 9,   MMP9↓, 90,   MMP9↑, 4,   MMPs↓, 35,   MUC4↓, 2,   N-cadherin↓, 20,   PDGF↓, 5,   Rac1↓, 2,   RECK↑, 1,   Rho↓, 4,   Rho↑, 1,   ROCK1↓, 5,   ROCK1↑, 1,   Slug↓, 7,   Smad1↓, 1,   SMAD3↓, 1,   Snail↓, 12,   TET1?, 1,   TET1↑, 5,   TGF-β↓, 10,   TIMP1↓, 1,   TIMP1↑, 13,   TIMP2↑, 11,   TIMP3↑, 1,   TRIB3↑, 3,   TSC1↑, 1,   TumCA↓, 4,   TumCI↓, 69,   TumCMig↓, 55,   TumCMig↑, 1,   TumMeta?, 1,   TumMeta↓, 86,   TumMeta↑, 7,   TumPF↓, 1,   Twist↓, 14,   TXNIP↑, 1,   Tyro3↓, 1,   uPA↓, 14,   uPAR↓, 1,   Vim↓, 25,   Vim↑, 1,   Zeb1↓, 9,   ZEB2↓, 2,   α-SMA↓, 2,   α-SMA↑, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 44,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 117,   angioG↑, 2,   CD31/PECAM-1↓, 6,   EGR1↑, 1,   EGR4↓, 1,   Endoglin↑, 2,   HIF-1↓, 7,   Hif1a↓, 62,   Hif1a↝, 1,   LOX1↓, 2,   NO↓, 4,   NO↑, 1,   PGI2↓, 1,   VCAM-1↓, 3,   VEGF↓, 100,   VEGF↑, 1,   VEGFR1↓, 3,   VEGFR2/KDR/Flk1↓, 8,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 16,   CLDN1↓, 4,   CLDN1↑, 1,   CX43/GJA1↓, 1,   EPR↑, 16,   GLUT1↓, 8,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↓, 2,   IBI↑, 1,   MMP↓, 80,   MMP↑, 2,   MPT↑, 6,   NHE1↓, 2,   OATPs↓, 2,   OCLN↑, 1,   TJ↓, 1,   TJ↑, 1,   TRPV1↑, 3,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 3,   CD4+↓, 1,   CD4+↑, 1,   CD44↓, 9,   CD47↓, 1,   CD8+↑, 2,   p‑cDC2↓, 1,   COX1↓, 2,   COX1↑, 1,   COX2/PTGS2↓, 71,   COX2/PTGS2↑, 5,   CXCL12↓, 1,   CXCR4↓, 9,   Dectin1↝, 1,   DR4↑, 5,   FOXP3↓, 2,   FOXP3↑, 1,   Gal-3↓, 1,   GM-CSF↓, 1,   HCAR1↓, 1,   HLA↑, 1,   HLA-I/II↑, 1,   HMGB1↓, 2,   ICAM-1↓, 5,   IFN-γ↓, 1,   IFN-γ↑, 3,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 6,   IL1↑, 1,   IL10↓, 4,   IL10↑, 3,   IL12↓, 1,   IL12↑, 1,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 20,   IL1β↑, 1,   IL2↓, 4,   IL2↑, 7,   IL4↑, 1,   IL6↓, 38,   IL8↓, 10,   Imm↑, 18,   Imm↝, 2,   INF-γ↓, 1,   Inflam↓, 42,   IRAK1↓, 1,   LRIG1↑, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 3,   MCT1↓, 2,   MDSCs↓, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   mPGES-1↓, 1,   NAF1↓, 1,   NF-kB?, 1,   NF-kB↓, 141,   NF-kB↑, 4,   p‑NF-kB↓, 1,   p‑NF-kB↑, 2,   NK cell↑, 7,   NLRP3↓, 3,   NLRP3↑, 2,   NOD1↓, 1,   p65↓, 4,   p‑p65↓, 2,   PD-1↓, 3,   PD-1↝, 2,   PD-L1↓, 11,   PGE1↓, 1,   PGE2↓, 22,   PSA↓, 12,   SOCS-3↓, 1,   T-Cell↑, 1,   TCF↓, 1,   Th1 response↑, 1,   TLR4↓, 5,   TLR4↝, 1,   TNF-α↓, 37,   TNF-α↑, 5,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   Treg lymp↓, 3,  

Cellular Microenvironment(tgid=17) ⓘ

pH↓, 1,   pH↑, 1,   e-pH↑, 2,   i-pH↓, 1,   TAMS↓, 1,   TAMS↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   PTN↓, 1,   SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

2/16-OHE1↑, 1,   2/16-OHE1↝, 1,   AhR↓, 1,   AhR↓, 1,   AR↓, 17,   AR↝, 2,   AR-FL↓, 1,   AR-V7↑, 1,   COMT↓, 2,   CYP17A1↓, 1,   CYP19↓, 2,   ENL↑, 1,   ER(estro)↓, 2,   ERα/ESR1↓, 1,   Estro↝, 1,   FGF21↓, 1,   FKBP5↓, 1,   PPARα↓, 2,   PPARγ↓, 1,   PPARγ↑, 3,   RANKL↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 176,   BioAv↑, 237,   BioAv⇅, 2,   BioAv↝, 74,   BioEnh?, 1,   BioEnh↑, 7,   CBR1↓, 1,   chemoR↓, 2,   ChemoSen?, 1,   ChemoSen↓, 2,   ChemoSen↑, 197,   ChemoSen⇅, 2,   CompStab?, 1,   CompStab↓, 7,   CompStab↑, 7,   CompStab↝, 3,   CYP1A1↓, 6,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP1A2↑, 2,   CYP2A3/CYP2A6↓, 1,   CYP2C9↓, 1,   CYP2E1↑, 1,   CYP3A2↓, 1,   CYP3A4↓, 4,   DDS↑, 10,   Dose?, 4,   Dose↓, 4,   Dose↑, 16,   Dose↝, 90,   Dose∅, 11,   DrugR↓, 1,   eff?, 1,   eff↓, 28,   eff↑, 129,   eff⇅, 1,   eff↝, 13,   eff∅, 3,   GSTA1↑, 2,   GSTM1↑, 1,   GSTZ1↓, 1,   GSTZ1↝, 1,   Half-Life↓, 33,   Half-Life↑, 12,   Half-Life↝, 36,   Half-Life∅, 5,   MDR1↓, 10,   MRP↓, 1,   MRP1/ABCC1↓, 5,   MRP1/ABCC1↑, 1,   MRP1/ABCC1↝, 1,   P-gp/ABCB1↓, 22,   P-gp/ABCB1↑, 3,   P-gp/ABCB1⇅, 1,   P450↓, 4,   RadioS?, 1,   RadioS↑, 69,   RadioS↝, 1,   selectivity?, 1,   selectivity↑, 86,   selectivity↝, 1,   selectivity∅, 1,   Synergy↑, 112,   Synergy↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 6,   ALAT↑, 1,   ALP↓, 2,   AR↓, 17,   AR↝, 2,   ascitic↓, 1,   AST↓, 4,   AST↑, 1,   BMD↑, 1,   BP↓, 2,   BRAF↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CEA↓, 2,   CEC↝, 1,   CRP↓, 2,   E6↓, 2,   E7↓, 2,   EGFR↓, 30,   EGFR↑, 2,   p‑EGFR↓, 1,   ERα/ESR1↓, 1,   EZH2↓, 5,   Ferritin↓, 1,   FOXM1↓, 4,   HER2/EBBR2↓, 7,   hTERT/TERT↓, 13,   IL6↓, 38,   KRAS↓, 2,   LDH↓, 5,   LDH↑, 1,   LDH↝, 1,   Myc↓, 5,   NOS2↓, 1,   NOS2↑, 1,   NSE↓, 1,   PD-L1↓, 11,   PSA↓, 12,   TF-Ag↓, 1,   TG/TAG↓, 1,   TP53↑, 4,   TRIB3↑, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiArt↑, 1,   AntiCan↓, 3,   AntiCan↑, 79,   AntiCan∅, 1,   antiD↑, 1,   AntiDiabetic↑, 1,   antiNeop↑, 3,   antiPs↑, 1,   AntiTum↑, 29,   cachexia↓, 3,   cardioP↑, 22,   CardioT↓, 1,   CardioT↑, 1,   chemoP↑, 41,   chemoPv↑, 22,   ChemoSideEff↓, 7,   cognitive?, 1,   cognitive↑, 4,   fatigue↓, 2,   hepatoP↓, 3,   hepatoP↑, 14,   memory↑, 4,   Mucositis↓, 1,   neuroP↑, 13,   NP/CIPN↓, 3,   NP/CIPN↑, 1,   Obesity↓, 1,   ORR↑, 1,   OS↑, 18,   OS↝, 1,   OS∅, 1,   Pain↓, 5,   PFS↓, 1,   PFS↑, 1,   PFS∅, 1,   QoL↑, 5,   QoL↝, 1,   radioP↑, 10,   Remission↑, 2,   RenoP↑, 5,   Risk↓, 29,   Risk↑, 1,   Sleep↑, 1,   toxicity↓, 38,   toxicity↑, 8,   toxicity⇅, 2,   toxicity↝, 21,   toxicity∅, 4,   TumVol↓, 20,   TumW↓, 7,   Weight↑, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiViral↑, 1,   Bacteria↓, 1,   Dectin1↝, 1,   GutMicro↑, 11,   GutMicro↝, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 2,   Ingr↝, 3,  
Total Targets: 1036

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 1,   antiOx?, 1,   antiOx↓, 16,   antiOx↑, 188,   ARE↑, 4,   ARE↝, 1,   Catalase↓, 1,   Catalase↑, 67,   Fenton↓, 2,   GPx↓, 1,   GPx↑, 53,   GPx1↑, 2,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 65,   GSR↑, 9,   GSTs↓, 3,   GSTs↑, 17,   H2O2↓, 7,   H2O2↑, 1,   H2O2∅, 2,   HDL↑, 5,   HDL∅, 1,   HNE↓, 1,   HO-1↓, 2,   HO-1↑, 46,   HO-2↓, 1,   Iron↓, 1,   Keap1↓, 2,   Keap1↑, 2,   Keap1↝, 1,   lipid-P↓, 57,   mt-lipid-P↓, 1,   MDA↓, 51,   MPO↓, 11,   NADH↓, 1,   NOX↓, 1,   NQO1↑, 10,   NQO1↝, 1,   NQO1∅, 1,   Nrf1↑, 2,   NRF2?, 1,   NRF2↓, 3,   NRF2↑, 74,   NRF2⇅, 1,   NRF2↝, 1,   Prx↑, 1,   RNS↓, 5,   ROS?, 1,   ROS↓, 222,   ROS↑, 4,   ROS⇅, 4,   ROS∅, 2,   mt-ROS?, 1,   selenoP↑, 4,   SOD↓, 5,   SOD↑, 96,   mt-SOD↑, 1,   SOD1↑, 5,   SOD2↑, 3,   TAC↑, 7,   TBARS↓, 2,   Thiols↑, 1,   Trx↑, 2,   Trx1↑, 1,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 5,   VitE↑, 4,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   IronCh↑, 13,   IronCh↝, 1,   Mets↝, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 2,   compII↑, 2,   compIII↑, 2,   compIV↑, 1,   DRP1/DNM1L↓, 1,   ETC↑, 1,   Insulin↓, 2,   Insulin↑, 4,   Insulin↝, 1,   MFN2↑, 1,   mtDam↓, 4,   OCR↓, 1,   OCR↑, 2,   OXPHOS↑, 1,   PGC-1α↑, 4,   PGC-1α↝, 1,   PINK1↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   15-LOX/ALOX15↓, 1,   5LO↓, 5,   ACC↓, 1,   Acetyl-CoA↑, 1,   adiP↑, 1,   ALAT↓, 18,   ALAT∅, 2,   AMPK↓, 2,   AMPK↑, 16,   AMPK↝, 1,   ATP↓, 1,   ATP↑, 11,   Buty↑, 1,   cAMP↑, 2,   CRM↑, 1,   cytoP450↓, 1,   DHODH↓, 1,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 1,   FFA/NEFA↓, 1,   G6PD↑, 1,   glucose↓, 8,   glucose↝, 4,   GlucoseCon↑, 5,   GlutMet↑, 1,   glyC↓, 1,   Glycolysis↓, 1,   GSK‐3β↓, 13,   GSK‐3β↑, 3,   p‑GSK‐3β↑, 1,   H2S↑, 1,   HMG-CoA↓, 2,   LDHA↑, 1,   LDL↓, 15,   lipidLev↓, 6,   lipoGen↓, 1,   NAD↓, 1,   NAD↑, 2,   NADH:NAD↑, 1,   NADPH↓, 3,   NADPH↑, 4,   PDK1 / PDPK1↓, 1,   PFK↓, 1,   PLA2↓, 2,   SCFAs↑, 1,   SIRT1↑, 21,   SIRT1↝, 1,   SIRT2↑, 1,   SREBF2↓, 1,   SREBF2⇅, 1,   SREBP1/SREBF1↓, 1,   SREBP1/SREBF1↑, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Apoptosis↓, 15,   ASC↓, 1,   BAX↓, 11,   Bax:Bcl2↓, 2,   Bcl-2↓, 3,   Bcl-2↑, 9,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 24,   cl‑Casp3↓, 1,   Casp6↓, 1,   Casp8↓, 1,   Casp9↓, 11,   Casp9↑, 1,   Cyt‑c↓, 5,   Cyt‑c∅, 1,   Fas↓, 1,   Ferroptosis↓, 2,   GranB/GZMB↓, 1,   iNOS↓, 27,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 3,   Pyro↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 5,   Akt↑, 19,   Akt↝, 1,   p‑Akt↓, 1,   p‑Akt↑, 3,   Akt2↓, 1,   AMPKα↑, 1,   CREB↑, 4,   p‑CREB↑, 1,   ERK↓, 6,   ERK↑, 5,   p‑ERK↑, 3,   HGF/c-Met↑, 1,   IGF-1R↓, 1,   IKKα↓, 2,   JAK↓, 2,   JAK2↓, 1,   JAK2↑, 1,   JNK↓, 7,   p‑JNK↓, 3,   MAPK↓, 17,   MAPK↑, 2,   MAPK↝, 2,   mTOR↓, 3,   mTOR↑, 5,   mTOR↝, 1,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 5,   PI3K↑, 10,   PI3K↝, 1,   PKCδ↓, 2,   PKCδ↑, 2,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 1,   STAT↓, 2,   STAT3↓, 3,   STAT3↑, 3,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ac-histone H3↑, 1,   AntiThr↑, 7,   ATF2↑, 1,   ATF4↓, 3,   DNMT1↓, 1,   FOXO↑, 1,   FOXO3↑, 1,   H3↑, 1,   H4↑, 1,   HATs↓, 1,   HDAC↓, 3,   HDAC↑, 2,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 2,   HOTAIR↑, 1,   other?, 3,   other↓, 10,   other↑, 23,   other↝, 41,   PhotoS↑, 1,   SOX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 4,   CHOP/DDIT3↑, 1,   eIF2α↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 7,   GRP78/BiP↓, 4,   GRP78/BiP↑, 2,   GRP94↑, 1,   HSP70/HSPA5↑, 3,   HSP70/HSPA5↝, 1,   HSP90↑, 1,   HSPs↑, 2,   IRE1↓, 1,   PERK↓, 1,   UPR↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 5,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↓, 2,   LC3II↑, 1,   MitoP↓, 1,   p62↑, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   DNAdam↓, 13,   DNArepair↑, 3,   P53↓, 3,   PARP1↓, 1,   PCNA↓, 2,   Telomerase↓, 1,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   E2Fs↑, 1,   GADD34↓, 1,   Ki-67↓, 2,   Ki-67↑, 1,   P21↓, 1,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,   Choline↑, 2,   Diff↝, 1,   FGF↑, 1,   GH↑, 1,   HH↓, 1,   HMGCR↓, 1,   IGF-1↓, 1,   IGF-1↑, 1,   IGFBP3↑, 1,   Ki-67↓, 2,   Ki-67↑, 1,   Nestin↑, 1,   neuroG↑, 8,   NOTCH1↑, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 3,   AntiAg↑, 25,   AP-1↓, 7,   BACH1↓, 1,   Ca+2↓, 3,   Ca+2↑, 2,   Ca+2↝, 1,   Cartilage↑, 2,   COL1↓, 3,   Fibrosis↓, 1,   LRP1↑, 1,   MLC2/MYL9↝, 1,   MMP13↓, 2,   MMP2↓, 2,   MMP2↑, 2,   MMP3↓, 1,   MMP9↓, 10,   MMPs↓, 4,   MUC1↑, 1,   N-cadherin↑, 1,   Rho↓, 1,   ROCK1↓, 1,   p‑SMAD2↓, 2,   p‑SMAD3↓, 1,   p‑SMAD3↑, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 5,   TGF-β↑, 2,   TGF-β1↓, 2,   TGF-β1↑, 1,   TIMP1↓, 1,   TregCell↑, 1,   TXNIP↓, 1,   uPA↑, 1,   α-SMA↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 3,   CD31/PECAM-1↑, 1,   E-sel↓, 1,   NO↓, 20,   NO↑, 3,   TXA2↓, 2,   VCAM-1↓, 8,   VEGF↓, 2,   VEGF↑, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↓, 7,   BBB↑, 53,   BBB↝, 3,   BBB∅, 3,   EPR↑, 1,   GastroP↑, 6,   GLUT2↑, 2,   GLUT3↑, 1,   GLUT4↑, 3,   H+/K+-ATPase↓, 1,   IBI↑, 5,   memfluid↑, 2,   MMP↓, 1,   MMP↑, 16,   MMP∅, 1,   MUC19↓, 1,   MUC2↓, 1,   OCLN↓, 1,   OCLN↝, 1,   TJ↑, 3,   TRPA1↑, 1,   TRPV1↑, 2,   TRPV3↑, 2,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   CB2 / CNR2↑, 1,   CD4+↑, 2,   CD8+↑, 1,   COX1↓, 9,   COX2/PTGS2↓, 57,   COX2/PTGS2↑, 1,   CXCR4↓, 1,   HMGB1↓, 2,   ICAM-1↓, 5,   IFN-γ↓, 5,   IFN-γ↑, 1,   IL1↓, 5,   IL10↓, 5,   IL10↑, 6,   IL12↓, 2,   IL17↓, 4,   IL18↓, 3,   IL1α∅, 1,   IL1β↓, 47,   IL1β∅, 1,   IL2↓, 5,   IL22↓, 1,   IL33↓, 1,   IL4↓, 5,   IL4↑, 1,   IL5↓, 2,   IL6↓, 56,   IL6↑, 3,   IL8↓, 12,   IL8↑, 1,   IL8∅, 1,   Imm↓, 2,   Imm↑, 20,   Imm⇅, 1,   Imm↝, 2,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 217,   Inflam↑, 6,   IRF3↓, 1,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 5,   MCP1/CCL2↑, 1,   MCP1/CCL2∅, 1,   MCT1↓, 1,   MIP‑1α/CCL3↓, 1,   MyD88↓, 1,   NeuroI↓, 3,   NF-kB↓, 77,   NF-kB↑, 3,   p‑NF-kB↓, 1,   NLRP3↓, 14,   NLRP3↑, 2,   p65↓, 2,   PGE2↓, 19,   RAGE↓, 3,   RANTES↓, 1,   TLR2↓, 4,   TLR3↓, 1,   TLR4↓, 9,   TLR4↑, 1,   TNF-α↓, 79,   TNF-α↑, 2,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 6,   Ach↑, 6,   AChE↓, 30,   AChE↑, 2,   ADAM10↑, 3,   BChE↓, 9,   BDNF↓, 1,   BDNF↑, 19,   ChAT↑, 6,   GABA↑, 5,   MAOA↓, 6,   MAOA↝, 1,   MAOB↓, 2,   monoA↑, 1,   NGF↑, 6,   PSD95↑, 4,   SNAP25↑, 2,   TPH1↓, 1,   TrkB↑, 4,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 7,   APOE4↓, 1,   APP↓, 6,   cl‑APP↑, 1,   Aβ↓, 54,   Aβ42↓, 4,   BACE/β-secretase↓, 15,   PSEN1/PS1↑, 1,   tau↓, 16,   p‑tau↓, 7,   XO↓, 1,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   cortisol↑, 1,   CYP19↓, 2,   DHT↑, 1,   GLP-1R↑, 1,   GR↑, 1,   PPARα↑, 4,   PPARγ↓, 3,   PPARγ↑, 8,   p‑PPARγ↓, 1,   SHBG↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv?, 2,   BioAv↓, 211,   BioAv↑, 354,   BioAv⇅, 4,   BioAv↝, 171,   BioAv∅, 3,   BioEnh↑, 6,   ChemoSen↑, 4,   CompStab↓, 1,   CompStab↑, 10,   CompStab↝, 3,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 2,   CYP3A2↓, 1,   DDS↑, 1,   Dose?, 4,   Dose↑, 9,   Dose⇅, 2,   Dose↝, 117,   Dose∅, 4,   eff↓, 5,   eff↑, 58,   eff↝, 7,   GSTA1↓, 1,   GSTA1↑, 1,   Half-Life?, 2,   Half-Life↓, 34,   Half-Life↑, 19,   Half-Life↝, 58,   Half-Life∅, 6,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 7,   P450↓, 3,   P450↑, 2,   P450↝, 1,   Synergy↑, 34,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 18,   ALAT∅, 2,   ALB↑, 1,   ALP↓, 4,   anemia↓, 1,   AST↓, 20,   AST∅, 2,   BG↓, 2,   BloodF↑, 7,   BMD↑, 5,   BP↓, 17,   BP↝, 1,   p‑BRCA1↑, 1,   creat↓, 3,   CRP↓, 8,   Ferritin↓, 1,   Ferritin↑, 1,   HemoG↑, 1,   HOMA↓, 1,   hs-CRP↓, 3,   IL6↓, 56,   IL6↑, 3,   IRes↓, 1,   IRes↑, 2,   IRes↝, 1,   LDH↓, 6,   NOS2↓, 2,   RAGE↓, 3,   RBC↑, 1,   TC↓, 2,   TG/TAG↓, 2,   TMAO↓, 1,   Urea↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 5,   AntiAge↑, 12,   antiAll↑, 19,   AntiArt↑, 8,   AntiCan↓, 1,   AntiCan↑, 35,   antiCG↝, 1,   AntiDiabetic↓, 2,   AntiDiabetic↑, 48,   AntiMyl↑, 1,   antiPs↑, 4,   AntiTum↓, 2,   AntiTum↑, 6,   Appetite↓, 1,   cardioP↓, 2,   cardioP↑, 95,   cardioP⇅, 1,   CardioT↓, 2,   chemoP↑, 15,   chemoPv↑, 13,   cognitive↓, 2,   cognitive↑, 76,   cognitive↝, 1,   cognitive∅, 2,   cough?, 1,   diuretic↑, 3,   hepatoP↓, 3,   hepatoP↑, 67,   Learn↑, 5,   memory↓, 1,   memory↑, 60,   motorD↓, 1,   motorD↑, 10,   Mucositis↓, 2,   neuroP↓, 2,   neuroP↑, 168,   neuroP↝, 1,   Obesity↓, 26,   OS↑, 4,   Pain↓, 11,   radioP↑, 9,   RenoP↓, 1,   RenoP↑, 20,   RenoP↝, 1,   Risk↓, 6,   Risk↑, 3,   Sleep↑, 2,   SoreThr?, 1,   Strength↑, 2,   Stroke↓, 16,   toxicity?, 2,   toxicity↓, 75,   toxicity↑, 13,   toxicity⇅, 1,   toxicity↝, 27,   toxicity∅, 12,   Weight↓, 4,   Weight↝, 1,   Wound Healing↑, 8,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 20,   AntiFungal↑, 7,   AntiP↑, 1,   AntiViral↑, 16,   Bacteria↓, 40,   Diar↓, 2,   GutMicro↑, 40,   GutMicro↝, 2,   Sepsis↓, 4,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,   Ingr↑, 5,   Ingr↝, 9,  
Total Targets: 622

Scientific Paper Hit Count for: BioAv, bioavailability
49 Curcumin
21 Sulforaphane (mainly Broccoli)
20 chitosan
20 Quercetin
20 EGCG (Epigallocatechin Gallate)
18 Baicalein
18 Chlorogenic acid
17 Resveratrol
15 Berberine
15 Selenium NanoParticles
15 Chrysin
15 Luteolin
15 Lycopene
14 Apigenin (mainly Parsley)
14 Pterostilbene
13 Kaempferol
12 Thymoquinone
11 Silymarin (Milk Thistle) silibinin
11 Honokiol
10 Alpha-Lipoic-Acid
10 Rosmarinic acid
10 Magnolol
9 Astaxanthin
9 borneol
9 Carvacrol
9 Morin
9 Urolithin
8 Broccoli
8 Capsaicin
8 Crocetin
8 Diindolylmethane
8 Emodin
8 Ferulic acid
8 Fucoidan
8 Piperlongumine
7 Allicin (mainly Garlic)
7 Artemisinin
7 Betulinic acid
7 Hydroxycinnamic-acid
7 Piperine
7 Fisetin
7 Flaxseed/Linseed
7 HydroxyTyrosol
7 Isoliquiritigenin
7 isoquercitrin
7 Phenethyl isothiocyanate
6 Silver-NanoParticles
6 Ashwagandha(Withaferin A)
6 Biochanin A
6 Rutin
6 Propolis -bee glue
6 Ellagic acid
6 Eugenol
5 beta-glucans
5 Baicalin
5 Boswellia (frankincense)
5 Thymol-Thymus vulgaris
5 Centella asiatica / Gotu kola → asiaticoside
5 Cucurbitacin
5 Formononetin
5 SDG/lignans
5 Gallic acid
5 Inositol
5 Naringin
5 Selenite (Sodium)
4 1,8-Cineole
4 5-Hydroxytryptophan
4 Beta-Caryophyllene
4 Boron
4 Caffeic acid
4 Melatonin
4 Celastrol
4 phytic acid, Inositol hexakisphosphate
4 Garcinol
4 Isovitexin
4 Lactoferrin/Talactoferrin
4 Matrine
4 Phenylbutyrate
4 Phycocyanin
4 Vitamin C (Ascorbic Acid)
4 Shikonin
4 Aflavin-3,3′-digallate
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Berbamine
3 Folic Acid, Vit B9
3 Chocolate
3 Cinnamon
3 Coenzyme Q10
3 Copper and Cu NanoParticles
3 Diclofenac
3 Indole-3-carbinol
3 Disulfiram
3 Fenbendazole
3 Gambogic Acid
3 Genistein (soy isoflavone)
3 Glabrescione B
3 Gossypol/AT-101
3 Grapeseed extract
3 Lapatinib
3 Licochalcone A
3 Licorice
3 Lecithin
3 Linalool
3 Lutein
3 Methylene blue
3 mebendazole
3 Metformin
3 Magnetic Fields
3 Niclosamide (Niclocide)
3 Selenium
3 Silicic Acid
3 Spermidine
3 Terpinen-4-ol / Tea Tree Oil
2 3-bromopyruvate
2 Auranofin
2 Astragalus
2 Citric Acid
2 Aspirin
2 Paclitaxel/Taxol
2 Atorvastatin
2 immunotherapy
2 doxorubicin
2 Docetaxel
2 Radiotherapy/Radiation
2 buckwheat sprouts
2 Butyrate
2 Cynanbungeigenin C (CBC) and D (CBD)
2 Chlorophyllin
2 Choline
2 Camptothecin
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Dasatinib/Phyrago
2 Dichloroacetate
2 Deguelin
2 D-limonene
2 Evodiamine
2 flavonoids
2 MCT oil
2 Shilajit/Fulvic Acid
2 Geraniol
2 Ginkgolide B
2 Ginkgetin
2 Hydrogen Gas
2 HydroxyCitric Acid
2 isoflavones
2 isoorientin
2 itraconazole
2 Ivermectin
2 Lapachol
2 Lemongrass Extract/Citral
2 Methyl salicylate / Sweet Birch oil
2 magnetic nanoparticles
2 Magnesium
2 Mushroom Lion’s Mane, Hericium erinaceus
2 nicotinamide adenine dinucleotide
2 Oleuropein
2 Turmerones
2 Ursolic acid
1 Aluminum
1 Anethole/trans-Anethole
1 Aromatherapy
1 Gemcitabine (Gemzar)
1 Aloe anthraquinones
1 xanthohumol
1 beta-carotene(VitA)
1 Bicalutamide
1 Bacopa monnieri
1 α-Bisabolol / Chamomile oil
1 Bullatacin
1 Carnosic acid
1 urea
1 capecitabine
1 Catechins
1 Cat’s Claw
1 Cannabidiol
1 Zinc
1 Citicoline, CDP-Choline
1 irinotecan
1 Polyphenols
1 Cyclopamine
1 Dichloroacetophenone(2,2-)
1 Dandelion Root
1 Echinacea
1 Ginkgo biloba-EGb 761
1 Electrical Pulses
1 Eurycomanone
1 Sesame seeds and Oil
1 Mung Bean Sprouts
1 tamoxifen
1 Gamma-aminobutyric acid
1 Ginkgo biloba
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Geldanamycin
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Arsenic trioxide
1 Graviola
1 Germacranolide sesquiterpene lactone
1 Hibiscus sabdariffa
1 Hyperthermia
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Isobavachalcone
1 iodine
1 Anthocyanins
1 L-Theanine
1 Modified Citrus Pectin
1 Bicarbonate(Sodium)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 Cisplatin
1 Psoralidin
1 Parthenolide
1 enzalutamide
1 Rauwolfia serpentina/Indian Snakeroot
1 salinomycin
1 Chemotherapy
1 Date Fruit Extract
1 cetuximab
1 Tomatine
1 Vitamin B3,Niacin
1 Vitamin D3
1 Vitamin E
1 Vitamin K2
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:792  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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