eff Cancer Research Results

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Scientific Papers found: Click to Expand⟱
2263- dietMet,    Methionine Restriction and Cancer Biology
- Review, Var, NA
AntiCan↑, TumCP↓, TumCG↓, selectivity↑, ChemoSen↓, RadioS↑, Insulin↓, *GlucoseCon↑, *ROS↓, *antiOx↑, *GSH↑, GSH↑, eff↑, polyA↓, TS↓, Raf↓, Akt↓, Casp9↑, Bak↑, P21↑, p27/CDKN1B↑, Insulin↓, IGF-1↓,
2264- dietMet,    Methionine restriction for cancer therapy: From preclinical studies to clinical trials
- Review, Var, NA
TumCP↓, *ROS?, ChemoSen↑, RadioS↑, Synergy↑, ROS↑, selectivity↑, TS↓, eff↑,
2265- dietMet,    Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase
- in-vivo, Nor, NA
*SCD1↓, *Weight↓, *Insulin↓, *IGF-1↓, *adiP↑, *eff↓,
2266- dietMet,    Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction
- in-vivo, Nor, NA
*ROS↓, eff↓,
2170- dietMet,    Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population
- Study, Var, NA
OS↑, eff↝, other↝,
2271- dietMet,    A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension
- Review, Nor, NA
*eff↑, *OS↓, *ROS↓, *Weight↓,
2268- dietMet,    Methionine dependency and cancer treatment
- Review, Var, NA
ChemoSen↑, *eff↑, selectivity↑, Synergy↑,
5192- dietMet,    Intermittent methionine restriction reduces IGF‐1 levels and produces similar healthspan benefits to continuous methionine restriction
- in-vivo, Nor, NA
OS↑, eff↝, IGF-1↓, adiP↑, Leptin↓, Weight↓,
5191- dietMet,    Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade
- in-vitro, Colon, HT29
ChemoSen↑, RadioS↑, Ferroptosis↑, Synergy↑, eff↑, GSH↓, eff↓,
2165- dietP,  SFN,    Broccoli sprout supplementation in patients with advanced pancreatic cancer is difficult despite positive effects—results from the POUDER pilot study
- Trial, PC, NA
Dose↝, OS↑, eff↝,
2161- dietP,    Plant-Based Diets and Cancer Prognosis: a Review of Recent Research
- Review, NA, NA
OS↑, eff↑, eff↑,
2157- dietP,    Plant-Based Diets and Disease Progression in Men With Prostate Cancer
- Study, Pca, NA
TumCG↓, Risk↓, eff↑,
2156- dietP,    Phytochemical-rich vegetable and fruit juice alleviates oral mucositis during concurrent chemoradiotherapy in patients with locally advanced head and neck cancer
- Human, HNSCC, NA
chemoP↑, radioP↑, eff↑,
2155- dietP,    Transepithelial Anti-Neuroblastoma Response to Kale among Four Vegetable Juices Using In Vitro Model Co-Culture System
- in-vivo, neuroblastoma, Caco-2 - NA, NA, SH-SY5Y
AntiCan↑, ROS↑, eff↑, eff↑, eff↑,
1626- dietSTF,  dietFMD,    When less may be more: calorie restriction and response to cancer therapy
- Review, Var, NA
CRM↑, ChemoSen↑, RadioS↑, eff↑, eff↑, IGF-1↓, TumCG↓, AMPK↑, eff↑, ChemoSen↑, RadioS↑, ROS↑, DNAdam↑, eff↑, HO-1↓,
5070- dietSTF,    A review of fasting effects on the response of cancer to chemotherapy
- Review, Var, NA
chemoP↑, ChemoSen↑, *DNArepair↑, *Apoptosis↓, *CD8+↑, UPR↑, eff↝, TumAuto↑,
4159- dietSTF,  2DG,  CRMs,    Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms
- Review, AD, NA
*BDNF↑, *HSPs↑, *eff↑,
3708- dietSTF,    Fasting as a Therapy in Neurological Disease
- Review, Nor, NA
*PGC-1α↑, *AMPK↑, *adiP↑, *glucose↓, *Insulin↓, *mTOR↓, *IL6↓, *TNF-α↓, *cognitive↑, *Inflam↓, *eff↑, *neuroP↑, ChemoSen↑, eff↓, chemoP↑, *eff↑,
6734- Dipy,  Cisplatin,    Adenosine enhances cisplatin sensitivity in human ovarian cancer cells
- in-vitro, Ovarian, NA
ChemoSen↑, eff↓, ADO↓,
6277- DL,  docx,    d-Limonene sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosis
- in-vitro, Pca, DU145 - in-vitro, Nor, PZ-HPV-7
ChemoSen↑, selectivity↑, ROS↑, GSH↓, Casp↑, eff↓, TumCP↓, cl‑Casp9↑, cl‑Casp3↑, P21↑, BAD↑, cl‑PARP↑, Bcl-xL↓, P53↑, mtDam↑, *toxicity↓,
6281- DL,    Applications of Limonene in Neoplasms and Non-Neoplastic Diseases
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
*antiOx↑, AntiTum↑, *AntiDiabetic↑, *neuroP↑, *GastroP↑, *ROS↓, *toxicity↓, *BioAv↑, ChemoSen↑, BAX↑, P53↓, Bcl-2↓, iNOS↓, COX2/PTGS2↓, eff↑, ROS↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, TumCMig↓, *lipid-P↓, *GSH↑, *SOD↑, *GPx↑, *hepatoP↑, *glucose↓, *AGEs↓, *Obesity↓, *Aβ↓, *AChE↓,
5386- docx,  AsP,    Co-delivery of docetaxel and palmitoyl ascorbate by liposome for enhanced synergistic antitumor efficacy
- vitro+vivo, Liver, HepG2 - in-vitro, BC, MCF7 - in-vitro, Pca, PC3
Dose↝, ROS↑, eff↑, Synergy↑,
6342- DRE,    Mechanistic Study on the Inhibitory Effect of Dandelion Extract on Breast Cancer Cell Proliferation and Its Induction of Apoptosis
- in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
eff↑, selectivity↑, Apoptosis↑, TumCCA↑, PI3K↓, Akt↓, JAK1↓, STAT↓, PPARγ↑, TumCP↓, SIRT6↓, SCD1↓, STAT3↓, Casp8↓, STAT6↓, PAK1↓, FABP4↓,
6348- DRE,    New prospects in oncotherapy: bioactive compounds from Taraxacum officinale
- Review, Var, NA
Ingr↝, TumCP↓, toxicity↓, *AntiDiabetic↑, *antiOx↑, *hepatoP↑, *diuretic↑, *Inflam↓, *neuroP↑, *Imm↑, eff↑, Apoptosis↑, tumCV↓, selectivity↑, TumCMig↓, EMT↓, MMP2↓, MMP9↓, Wnt↓, β-catenin/ZEB1↓, PI3K↓, Akt↓, JNK↓, ERK↓,
6317- DRE,    The efficacy of dandelion root extract in inducing apoptosis in drug-resistant human melanoma cells
- in-vitro, Melanoma, A375
Apoptosis↑, selectivity↑, Casp8↑, mt-ROS↑, eff↑, *toxicity↓, Diff↑, TumCP↓, chemoPv↑, *ROS↓, *NO↓, *COX2/PTGS2↓, *RNS↓, TumCI↓, MMP2↓, MMP9↓, p‑Src↓, p‑FAK↓,
6320- DRE,    Selective induction of apoptosis and autophagy through treatment with dandelion root extract in human pancreatic cancer cells
- in-vitro, PC, Bxpc-3 - in-vitro, PC, PANC1
Apoptosis↑, MMP↓, TumAuto↑, selectivity↑, eff↑, Casp8↑, Casp3↑, cl‑BID↑, mtDam↑, ROS↑,
6322- DRE,  LGE,    Dandelion Root and Lemongrass Extracts Induce Apoptosis, Enhance Chemotherapeutic Efficacy, and Reduce Tumour Xenograft Growth In Vivo in Prostate Cancer
- vitro+vivo, Pca, DU145
AntiCan↑, ChemoSen↑, Dose↝, *ROS↓, Apoptosis↑, selectivity↑, *toxicity↓, *chemoP↑, eff↓, ROS↑,
6354- DRE,    Taraxacum officinale L. in leukemia and lymphoma: current knowledge and prospects for horticulture
- Review, AML, NA
ROS↑, mt-Apoptosis↑, TumCCA↑, PI3K↓, Akt↓, STAT3↓, Dose↝, *hepatoP↑, Casp8↑, mtDam↑, TumCD↑, selectivity↑, DNAdam↑, BAX↑, P53↑, Bcl-2↓, CSCs↓, *toxicity↓, tumCV↓, Imm↑, FAK↓, mTOR↓, ChemoSen↑, eff↝, eff↑,
6351- DRE,  Rad,    Differential effect of Taraxacum officinale L. (dandelion) root extract on hepatic and testicular tissues of rats exposed to ionizing radiation
- in-vivo, Nor, NA
*radioP↑, *ROS↓, *MDA↓, *GSH↑, *SOD↑, *IL1β↓, *TNF-α↓, *Casp3↓, *eff↑,
6738- DSF,    Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
- Review, Var, NA
eff↑, NPL4↓,
6744- DSF,    Disulfiram modulated ROS-MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, T47D
TumCD↑, ChemoSen↑, BAX↑, Apoptosis↑, CSCs↓, ROS↑, eff↝, JNK↑, p38↑, NF-kB↓,
6739- DSF,    Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase
- in-vitro, Lung, H1299 - in-vitro, Lung, A549
ALDH↓, eff↝, NPL4↓,
4913- DSF,    Anticancer effects of disulfiram: a systematic review of in vitro, animal, and human studies
- Review, Var, NA
Apoptosis↑, tumCV↑, eff↑, toxicity↓, antiNeop↑, ChemoSen↑, RadioS↑, OS↑, ROS↑, SOD↓, MMP1↓, Synergy↑, Half-Life↓,
4914- DSF,  immuno,    Disulfiram and cancer immunotherapy: Advanced nano-delivery systems and potential therapeutic strategies
- Review, Var, NA
AntiTum↑, eff↑, ALDH↓, Dose↝, RadioS↑, angioG↓, TumMeta↓, BioAv↝, ROS↑, DNAdam↑, P-gp/ABCB1↓, CSCs↓, EMT↓, Imm↑, SOD↓, MAPK↓, NF-kB↓, ChemoSen↑, Synergy↑, toxicity↝, BioAv↑, *Inflam↓, Sepsis↓,
5008- DSF,  Cu,    Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis
- in-vitro, HCC, NA
selectivity↑, TumCD↑, TumCMig↓, TumCI↓, angioG↓, mtDam↑, Iron↑, lipid-P↑, Ferroptosis↑, NF-kB↑, p‑p62↑, Keap1↓, eff↑, eff↓, ChemoSen↑,
5009- DSF,  Cu,    Activation of Oxidative Stress and Down-Regulation of Nuclear Factor Erythroid 2-Related Factor May Be Responsible for Disulfiram/Copper Complex Induced Apoptosis in Lymphoid Malignancy Cell Lines
- vitro+vivo, lymphoma, NA
AntiTum↑, ROS↑, JNK↑, NRF2↓, eff↓, TumCD↑,
5011- DSF,  Cu,    Leveraging disulfiram to treat cancer: Mechanisms of action, delivery strategies, and treatment regimens
- Review, Var, NA
BioAv↓, eff↓, ChemoSen↑, RadioS↑,
5012- DSF,  Cu,    Advancing Cancer Therapy with Copper/Disulfiram Nanomedicines and Drug Delivery Systems
- Review, Var, NA
ROS↑, ALDH↓, TumCP↓, CSCs↓, angioG↓, TumMeta↓, DNAdam↑, Proteasome↓, SOD1↓, GSR↓, ox-GSSG↑, GSH/GSSG↓, MMP↓, Akt↓, cycD1/CCND1↓, NF-kB↓, CSCs↓, MAPK↓, angioG↓, DrugR↓, EMT↓, Vim↓, BioAv↑, eff↑,
5006- DSF,  Cu,    Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition
- vitro+vivo, lymphoma, NA
TumCD↑, TumCP↑, Apoptosis↑, NRF2↓, ROS↑, p‑JNK↑, p65↓, eff↓, NF-kB↓,
4832- EA,    Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid
- Review, Var, NA
*antiOx↑, *AntiCan↑, TumCMig↓, angioG↓, ChemoSen↑, RadioS↑, *chemoP↑, *BioAv↓, eff↓, selectivity↑, MMP2↓, MMP9↓, VEGF↓, TumCCA↑, Apoptosis↑, ROS↑, BioAv↑,
1605- EA,    Ellagic Acid and Cancer Hallmarks: Insights from Experimental Evidence
- Review, Var, NA
*BioAv↓, antiOx↓, Inflam↓, TumCP↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, P53↑, P21↑, COX2/PTGS2↓, NF-kB↓, Akt↑, NOTCH↓, CDK2↓, CDK6↓, JAK↓, STAT3↓, EGFR↓, p‑ERK↓, p‑Akt↓, p‑STAT3↓, TGF-β↓, SMAD3↓, CDK6↓, Wnt/(β-catenin)↓, Myc↓, survivin↓, CDK8↓, PKCδ↓, tumCV↓, RadioS↑, eff↑, MDM2↓, XIAP↓, p‑RB1↓, PTEN↑, p‑FAK↓, Bax:Bcl2↑, Bcl-xL↓, Mcl-1↓, PUMA↑, NOXA↑, MMP↓, Cyt‑c↑, ROS↑, Ca+2↝, Endoglin↑, Diablo↑, AIF↑, iNOS↓, Casp9↑, Casp3↑, cl‑PARP↑, RadioS↑, Hif1a↓, HO-1↓, HO-2↓, SIRT1↓, selectivity↑, Dose∅, NHE1↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, PDK1 / PDPK1?, PDK1 / PDPK1?, ECAR↝, COX1↓, Snail↓, Twist↓, cMyc↓, Telomerase↓, angioG↓, MMP2↓, MMP9↓, VEGF↓, Dose↝, PD-L1↓, eff↑, SIRT6↑, DNAdam↓,
1619- EA,  CUR,    effect-of-the-ellagic-acid-and-curcumin-combinations-2161-0525-1000296.pdf">Antimutagenic Effect of the Ellagic Acid and Curcumin Combinations
- in-vitro, Nor, NA
eff↑,
1608- EA,    Ellagic Acid from Hull Blackberries: Extraction, Purification, and Potential Anticancer Activity
- in-vitro, Cerv, HeLa - in-vitro, Liver, HepG2 - in-vitro, BC, MCF7 - in-vitro, Lung, A549 - in-vitro, Nor, HUVECs
eff↑, Dose∅, *BioAv↑, selectivity↑, TumCP↓, Casp↑, PTEN↑, TSC1↑, mTOR⇅, Akt↓, PDK1 / PDPK1↓, E6↓, E7↓, DNAdam↑, ROS↑, *BioAv↓, *BioEnh↑, *Half-Life∅,
1611- EA,    Targeting Myeloperoxidase Activity and Neutrophil ROS Production to Modulate Redox Process: Effect of Ellagic Acid and Analogues
- in-vitro, Mal, NA
*BioAv↓, eff↑, *BioAv↓, ROS↑,
1618- EA,    A comprehensive review on Ellagic acid in breast cancer treatment: From cellular effects to molecular mechanisms of action
- Review, BC, NA
TumCCA↑, TumCMig↓, TumCI↓, TumMeta↓, Apoptosis↑, TGF-β↓, SMAD3↓, CDK6↓, PI3K↓, Akt↓, angioG↓, VEGFR2/KDR/Flk1↓, MAPK↓, NEDD9↓, NF-kB↓, eff↑, eff↑, RadioS↑, ChemoSen↑, DNAdam↑, eff↑, *toxicity∅, *toxicity∅,
6612- Ech,    Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial
- Trial, Nor, NA
*Imm↑, Dose↝, eff↑,
6606- Ech,  Cic,    Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis
- in-vitro, Colon, Caco-2 - in-vitro, Colon, HCT116
TumCP↓, Telomerase↓, Apoptosis↑, DNAdam↑, Casp9↑, cl‑PARP↑, β-catenin/ZEB1↓, eff↑,
6607- Ech,    Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines
- in-vitro, PC, MIA PaCa-2 - in-vitro, CRC, Colo320
tumCV↓, eff↑, Apoptosis↑, Casp3↑, Casp7↑, DNAdam↑, Imm↑, NK cell↑, PGE2↓, COX1↓, COX2/PTGS2↓, 5LO↓,
6619- Ech,    Echinacea Reduces Antibiotics by Preventing Respiratory Infections: A Meta-Analysis (ERA-PRIMA)
- Review, Nor, NA
*eff↑, *Imm↑, *AntiViral↑,
7200- EGb 761,  PCA,    Optimized Ginkgo biloba extract EGb 761®: boosted therapeutic benefits with minimized CYP enzyme interference
- in-vivo, Nor, NA
*Dose↝, *AChE↓, *GSK‐3β↝, *eff↑, *cognitive↑, *toxicity↓,

Showing Research Papers: 551 to 600 of 1416
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1416

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 21,   ARE/EpRE↑, 1,   Catalase↓, 12,   Catalase↑, 4,   Catalase∅, 1,   Copper↓, 1,   CoQ10↑, 1,   cystine↓, 1,   DJ-1↓, 1,   ENOX2↓, 2,   ENOX2↑, 1,   Fenton↑, 16,   GCLM↓, 1,   GPx↓, 8,   GPx↑, 5,   GPx1↓, 1,   GPx1↑, 1,   GPx4↓, 16,   GSH↓, 74,   GSH↑, 3,   GSH↝, 1,   GSH∅, 1,   i-GSH∅, 1,   mt-GSH↓, 1,   GSH/GSSG↓, 12,   GSR↓, 3,   GSSG↓, 1,   ox-GSSG↑, 1,   GSTs↓, 2,   GSTs↑, 2,   GSTs∅, 1,   H2O2?, 1,   H2O2↑, 17,   e-H2O2↓, 1,   i-H2O2↑, 1,   i-H2O2∅, 1,   mt-H2O2↑, 1,   HO-1↓, 8,   HO-1↑, 14,   HO-2↓, 1,   HO-2↑, 1,   hyperG↓, 1,   Iron↓, 1,   Iron↑, 11,   Iron↝, 2,   i-Iron↑, 2,   c-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 4,   lipid-P↑, 40,   MDA↓, 3,   MDA↑, 11,   MPO↓, 1,   NADH↑, 1,   NADHdeh?, 1,   NADPH/NADP+↓, 1,   NQO1↓, 2,   NQO1↑, 1,   Nrf1↑, 2,   NRF2↓, 17,   NRF2↑, 20,   NRF2↝, 3,   p‑NRF2↑, 1,   Prx↓, 1,   Prx3↑, 1,   Prx4↑, 1,   Prx6↑, 2,   PrxII↓, 1,   PYCR1↓, 1,   RNS↑, 2,   ROS?, 5,   ROS↓, 23,   ROS↑, 555,   ROS⇅, 7,   ROS↝, 5,   ROS∅, 1,   i-ROS↓, 1,   i-ROS↑, 6,   mt-ROS↑, 18,   RPM↑, 1,   SOD↓, 18,   SOD↑, 6,   mt-SOD↑, 1,   SOD1↓, 3,   SOD1↑, 2,   SOD2↓, 5,   SOD2↑, 4,   TAC↓, 3,   Thiols↓, 3,   i-Thiols↓, 1,   Trx↓, 6,   Trx↑, 1,   Trx1↓, 1,   ox-Trx1↑, 1,   Trx2↓, 1,   TrxR↓, 30,   TrxR↑, 1,   TrxR1↓, 10,   TrxR1↑, 1,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 6,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 5,   Ferritin↑, 1,   FTH1↓, 3,   IronCh↑, 4,   IRP1↑, 1,   Mets↑, 1,   NCOA4↑, 2,   Tf↓, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   CDC2↓, 3,   CDC25↓, 9,   CDC25↑, 2,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   compIII↑, 1,   EGF↓, 1,   ETC↓, 10,   ETC↝, 1,   HSP60/HSPD1↑, 1,   Insulin↓, 4,   MCU↓, 1,   mitResp↓, 8,   mitResp↑, 2,   MKK7↓, 1,   mtDam↑, 45,   OCR↓, 13,   OCR↑, 3,   mt-OCR↓, 1,   OXPHOS↓, 9,   OXPHOS↑, 6,   OXPHOS⇅, 1,   OXPHOS↝, 3,   mt-OXPHOS↑, 2,   PDH↓, 4,   PDH↑, 1,   p‑PDH↓, 1,   PGC-1α↑, 4,   PINK1↑, 4,   SDH↓, 3,   SIRT3↓, 1,   SIRT3↑, 1,   TrxR2↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 3,   5LO↓, 4,   ACC↓, 2,   ACC↑, 1,   p‑ACC↑, 1,   ACLY↓, 7,   p‑ACLY↓, 1,   ACSL4↑, 2,   adiP↑, 2,   ADO↓, 1,   ALAT↓, 2,   ALAT∅, 1,   ALDOA↓, 2,   AMP↑, 1,   AMPK↑, 25,   AMPK↝, 1,   p‑AMPK↑, 3,   ATP↓, 43,   ATP↑, 1,   ATP∅, 1,   i-ATP↓, 1,   i-ATP↑, 1,   Buty↑, 2,   CAIX/CA9↓, 2,   citrate↓, 1,   CPT1A↓, 1,   CRM↑, 1,   CRM↝, 1,   ECAR↓, 6,   ECAR↝, 1,   ENO1↓, 3,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 3,   FASN↑, 2,   FBPase↑, 1,   GAPDH↓, 3,   GLS↓, 1,   glucoNG↑, 1,   glucose↓, 2,   glucose↑, 1,   glucose∅, 1,   GlucoseCon↓, 15,   GlucoseCon↑, 2,   GlucoseCon∅, 1,   glut↓, 1,   glyC↓, 1,   Glycolysis↓, 51,   Glycolysis↑, 3,   Glycolysis↝, 1,   GSK‐3β↓, 10,   GSK‐3β↑, 4,   p‑GSK‐3β↓, 4,   p‑GSK‐3β↑, 1,   Histones↑, 1,   HK1↓, 1,   HK2?, 1,   HK2↓, 24,   HK2↑, 1,   HK2∅, 1,   HMG-CoA↓, 3,   KeyT↑, 1,   lactateProd↓, 26,   lactateProd↑, 4,   lactateProd∅, 1,   e-lactateProd↓, 1,   LDHA↓, 12,   LDHA↑, 1,   LDHA∅, 1,   LDL↓, 4,   lipidLev↓, 1,   lipidLev↑, 1,   lipoGen↓, 1,   MCT4↓, 1,   NAD↓, 2,   NADPH↓, 8,   NADPH↑, 1,   NH3↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 9,   PDKs↓, 4,   PFK↓, 6,   PFK1↓, 2,   PFK2?, 1,   PFK2↓, 1,   PFKP↓, 2,   PGK1↓, 2,   PGM1↓, 1,   PGM1∅, 1,   PKM2↓, 20,   p‑PKM2↓, 1,   polyA↓, 1,   PPP↓, 2,   PPP↑, 1,   Pyruv↓, 1,   SCD1↓, 3,   SCFAs↑, 2,   SIRT1↓, 9,   SIRT1↑, 6,   SREBP1/SREBF1↓, 2,   SREBP2↓, 1,   TCA?, 1,   TCA↓, 2,   TCA↑, 2,   TCA↝, 1,   TS↓, 3,   UGDH↓, 2,   Warburg↓, 11,   Warburg↑, 1,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 18,   APAF1↑, 5,   Apoptosis?, 1,   Apoptosis↓, 12,   Apoptosis↑, 357,   mt-Apoptosis↑, 6,   ASC↓, 1,   ASK1↑, 2,   p‑ASK1↑, 1,   aSmase↑, 1,   BAD↓, 1,   BAD↑, 10,   Bak↓, 1,   Bak↑, 11,   BAX↓, 6,   BAX↑, 145,   Bax:Bcl2↑, 38,   Bcl-2↓, 155,   Bcl-2↑, 4,   Bcl-2∅, 1,   Bcl-xL↓, 38,   Bcl-xL↑, 3,   BID↓, 1,   BID↑, 7,   p‑BID↓, 1,   cl‑BID↑, 2,   BIM↑, 7,   BNIP3?, 2,   BNIP3↑, 1,   BNIP3↝, 1,   Casp↓, 1,   Casp↑, 55,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp12?, 1,   Casp12↑, 2,   pro‑Casp12↓, 1,   Casp2↑, 3,   Casp3↓, 4,   Casp3↑, 176,   cl‑Casp3↑, 51,   cl‑Casp3∅, 1,   proCasp3↓, 3,   proCasp3↑, 3,   CASP4↑, 1,   Casp6↑, 1,   Casp7↑, 20,   cl‑Casp7↑, 5,   Casp8↓, 2,   Casp8↑, 41,   Casp8∅, 2,   cl‑Casp8↑, 4,   proCasp8↑, 2,   Casp9↓, 1,   Casp9↑, 105,   cl‑Casp9↓, 1,   cl‑Casp9↑, 20,   proCasp9↓, 1,   proCasp9↑, 2,   cFLIP↓, 5,   Cupro↑, 3,   Cyt‑c↓, 1,   Cyt‑c↑, 121,   Cyt‑c↝, 1,   Diablo↑, 5,   DIDO1/DIO-1↑, 1,   DR5↑, 23,   Endon↑, 1,   FADD↑, 5,   Fap1↓, 1,   Fas↓, 2,   Fas↑, 15,   FasL↓, 1,   FasL↑, 13,   FasL⇅, 1,   Ferroptosis↓, 4,   Ferroptosis↑, 30,   GranB/GZMB↑, 1,   GranB/GZMB↝, 1,   GSDMD↑, 3,   GSDME↑, 1,   cl‑GSDME↑, 1,   GSDME-N↑, 2,   IAP1↓, 7,   IAP2/BIRC3↓, 3,   ICD↑, 5,   iNOS↓, 9,   iNOS↑, 1,   Mcl-1↓, 24,   p‑Mcl-1↓, 1,   cl‑Mcl-1↑, 1,   MDM2↓, 13,   MDM2↑, 1,   p‑MDM2↓, 1,   MLKL↑, 3,   p‑MLKL↓, 1,   MOMP↓, 2,   MOMP↑, 5,   Necroptosis↑, 7,   necrosis↑, 10,   NOXA↑, 6,   p38↓, 3,   p38↑, 25,   p‑p38↓, 1,   p‑p38↑, 12,   Paraptosis↑, 4,   Perforin↑, 1,   Perforin↝, 1,   PUMA↑, 7,   Pyro↑, 9,   RIP1↓, 2,   RIP1↑, 2,   RIP3↑, 3,   p‑RIP3↑, 2,   SK↓, 1,   survivin↓, 50,   TRAIL↑, 5,   TumCD↓, 4,   TumCD↑, 55,   TumCD∅, 2,   TUNEL↑, 1,   XIAP↓, 22,   YAP/TEAD↓, 7,   YAP/TEAD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 1,   Akt↓, 115,   Akt↑, 6,   p‑Akt↓, 37,   p‑Akt↑, 4,   AKT1↓, 2,   AMPKα↑, 4,   BRAF↓, 1,   CaMKII ↓, 2,   CaMKII ↑, 1,   CK2↓, 2,   cMET↓, 2,   CREB↑, 1,   cSrc↓, 1,   DDIT4↑, 1,   EGFR↓, 24,   EGFR↑, 2,   p‑EGFR↓, 1,   ERK↓, 32,   ERK↑, 12,   p‑ERK↓, 12,   p‑ERK↑, 8,   e-ERK↑, 1,   FOXD3↑, 1,   HCAR2↑, 1,   HER2/EBBR2↓, 8,   HGF/c-Met↓, 1,   Hippo↓, 2,   Hippo↝, 1,   IGF-1R↓, 2,   IGFR↓, 2,   IKKα↓, 7,   IKKα↑, 3,   p‑IKKα↓, 1,   IκB↑, 2,   p‑IκB↓, 2,   JAK↓, 2,   JAK1?, 1,   JAK1↓, 1,   p‑JAK1↓, 1,   JAK2↓, 8,   p‑JAK2↓, 5,   JNK↓, 6,   JNK↑, 33,   p‑JNK↑, 13,   LATS1↓, 1,   MAPK↓, 22,   MAPK↑, 16,   p‑MAPK↓, 1,   p‑MAPK↑, 6,   MEK↓, 2,   p‑MEK↓, 2,   p‑MEK↑, 1,   MKK4↓, 1,   MKP1↓, 1,   MKP2↓, 1,   Mst1↑, 1,   mTOR↓, 59,   mTOR↑, 3,   mTOR⇅, 1,   mTOR↝, 1,   p‑mTOR↓, 12,   mTORC2↓, 1,   mTORC2↑, 1,   p70S6↓, 2,   P70S6K↓, 2,   p‑P70S6K↓, 2,   p85S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 82,   PI3K↑, 5,   p‑PI3K↓, 4,   PI3K/Akt↓, 1,   PIK3CA↓, 1,   PIK3CA↑, 1,   PKA↓, 3,   PKA↑, 1,   PKCδ↓, 5,   PTEN↓, 1,   PTEN↑, 15,   p‑PTEN↓, 1,   Raf↓, 3,   RAS↓, 4,   p‑RSK↑, 1,   p‑S6K↓, 1,   Sp1/3/4↓, 7,   Src↓, 2,   p‑Src↓, 2,   STAT↓, 4,   STAT3↓, 54,   STAT3↑, 3,   STAT3⇅, 1,   STAT3↝, 1,   p‑STAT3↓, 15,   p‑STAT3↑, 2,   mt-STAT3↓, 1,   STAT6↓, 2,   p‑STAT6↓, 1,   p‑STK11/LKB1↑, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF3↑, 1,   ATF4↑, 10,   ATF4↝, 1,   CBP↓, 1,   ChrMod↑, 1,   cJun↓, 2,   cJun↑, 3,   p‑cJun↑, 1,   cMyc↓, 31,   cMyc↑, 1,   DNMT1↓, 4,   DNMT1↑, 1,   DNMT3A↓, 1,   DNMTs↓, 5,   EZH2↓, 1,   FOXO1↑, 2,   FOXO3↓, 2,   FOXO3↑, 5,   FOXO4↑, 2,   H3↓, 3,   p‑H3↓, 1,   p‑H3↑, 1,   ac‑H3↓, 1,   ac‑H3↑, 2,   H3K27ac∅, 1,   H4↓, 1,   ac‑H4↓, 1,   ac‑H4↑, 1,   HATs↓, 1,   HATs↑, 1,   HDAC↓, 26,   HDAC1↓, 4,   HDAC10↓, 1,   HDAC10↑, 1,   HDAC2↓, 1,   HDAC3↓, 2,   HDAC8↓, 2,   IRF1↑, 1,   KLF2↓, 1,   KLF5↓, 1,   miR-124-3p↓, 1,   miR-129-5p↑, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 1,   miR-155↓, 1,   miR-199↓, 1,   miR-200b↑, 1,   miR-200c↑, 1,   miR-203↑, 1,   miR-21↓, 1,   miR-218↑, 1,   miR-22↑, 1,   miR-29b↑, 1,   miR-30a-5p↑, 2,   miR-375↑, 1,   miR-490↑, 1,   Myc↓, 5,   n-MYC↓, 1,   NDRG1↑, 1,   OCT4↓, 10,   other?, 4,   other↓, 8,   other↑, 18,   other↝, 63,   other∅, 2,   PhotoS↑, 3,   SD↑, 1,   SETBP1↓, 1,   sonoS↑, 2,   SOX2↓, 7,   SOX4↑, 1,   SOX9↓, 1,   SUV39H↓, 3,   TCF-4↓, 1,   TFE3↑, 2,   tumCV?, 1,   tumCV↓, 113,   tumCV↑, 3,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 33,   e-CRT↑, 1,   EDEM↑, 1,   eIF2α↓, 1,   eIF2α↑, 6,   p‑eIF2α↓, 1,   p‑eIF2α↑, 8,   ER Stress↓, 2,   ER Stress↑, 80,   ER Stress↝, 1,   ERStress↑, 1,   GRP78/BiP?, 1,   GRP78/BiP↓, 5,   GRP78/BiP↑, 18,   HSF1↓, 1,   HSP27↓, 1,   HSP27↑, 1,   HSP70/HSPA5↓, 6,   HSP70/HSPA5↑, 4,   e-HSP70/HSPA5↑, 1,   HSP90↓, 13,   HSP90↑, 2,   e-HSP90↑, 2,   ac‑HSP90↑, 1,   HSPs↑, 2,   HSPs∅, 1,   IRE1↑, 4,   NPL4↓, 2,   PERK↑, 9,   p‑PERK↓, 1,   p‑PERK↑, 1,   Proteasome↓, 4,   PSMB5↓, 1,   UPR↓, 1,   UPR↑, 14,   mt-UPR↑, 1,   XBP-1↑, 6,   XBP-1↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

APA↑, 1,   ATG3↓, 1,   ATG5↑, 5,   ATG7↑, 1,   Beclin-1/ATG6↓, 2,   Beclin-1/ATG6↑, 14,   p‑Beclin-1/ATG6↑, 1,   LAMP1?, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 3,   LC3B↑, 3,   LC3B-II↑, 5,   LC3II↑, 19,   LC3s↑, 2,   lysoMP↓, 1,   lysoMP↑, 1,   MitoP↑, 3,   p62↓, 11,   p62↑, 6,   p‑p62↑, 1,   PARK2↑, 4,   SESN2↑, 3,   TFEB↑, 1,   TumAuto↓, 5,   TumAuto↑, 75,   TumAuto↝, 1,   mt-TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↓, 1,   ATM↑, 5,   ATR↑, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   BRCA2↓, 3,   DNA-PK↑, 2,   DNAdam↓, 5,   DNAdam↑, 97,   mt-DNAdam↑, 1,   DNArepair↓, 3,   hTERT/TERT↓, 7,   MDMX↓, 1,   NKX3.1↓, 2,   p16↑, 3,   P53↓, 6,   P53↑, 72,   P53↝, 3,   P53∅, 1,   p‑P53↑, 6,   p53 Wildtype↓, 1,   PARP↓, 6,   PARP↑, 16,   p‑PARP↑, 1,   cl‑PARP↑, 103,   cl‑PARP∅, 1,   proPARP↓, 1,   cl‑PARP1↑, 4,   PCNA↓, 12,   SIRT6↓, 2,   SIRT6↑, 1,   Telomerase↓, 16,   TOP1↓, 4,   TOP1↑, 1,   TOP1↝, 1,   TOP2↓, 2,   TOP2↑, 2,   TP53↓, 2,   TRF2↓, 1,   UHRF1↓, 1,   γH2AX↑, 12,   p‑γH2AX↑, 5,  

Cell Cycle & Senescence(tgid=11) ⓘ

ANAPC2↑, 1,   AURKB↑, 1,   CDK1?, 1,   CDK1↓, 11,   p‑CDK1↓, 1,   p‑CDK1↑, 1,   CDK2↓, 20,   CDK4↓, 31,   CDK4↑, 3,   p‑CDK4↓, 1,   CDK6↓, 11,   CDK6↑, 5,   CDK8↓, 1,   CDKN2C/p18↑, 1,   cellSen↑, 1,   CHK1↓, 1,   Chk2↑, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 8,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 22,   CycB/CCNB1↑, 5,   cycD1/CCND1↓, 56,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   CycD3↓, 2,   CycD3↑, 1,   cycE/CCNE↓, 13,   cycE/CCNE↑, 1,   cycF↑, 1,   E2Fs↓, 1,   GADD45A↑, 2,   Ki-67↓, 26,   mitA↓, 1,   mitA↑, 1,   p19↑, 1,   P21↓, 3,   P21↑, 57,   p27/CDKN1B↑, 22,   PLK1↓, 1,   RB1↑, 2,   p‑RB1↓, 4,   TubPol↓, 1,   TumCCA?, 1,   TumCCA↓, 6,   TumCCA↑, 228,   UBE2C↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 9,   ALDH1A1↓, 4,   BMI1↓, 3,   CD133↓, 9,   CD24↓, 3,   CD34↓, 1,   cFos↓, 2,   cFos↑, 1,   cMYB↓, 1,   CSCs↓, 48,   CSCs↑, 2,   CSCsMark↓, 1,   Diff↓, 1,   Diff↑, 4,   FGF↓, 2,   Gli↓, 1,   Gli1↓, 6,   HH↓, 8,   HMGCR↓, 1,   IGF-1?, 1,   IGF-1↓, 18,   IGF-1↑, 1,   IGF-1↝, 1,   IGF-1∅, 1,   IGF-2↓, 1,   IGFBP1↓, 1,   IGFBP1↑, 3,   IGFBP3↑, 3,   Ki-67↓, 26,   Let-7↑, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 10,   Nestin↓, 1,   NOTCH↓, 4,   NOTCH↑, 1,   NOTCH1↓, 5,   NOTCH1↑, 1,   NOTCH3↓, 1,   p300↓, 1,   Piezo1↑, 1,   PTCH1↓, 2,   Shh↓, 4,   Smo↓, 4,   STAT1↓, 1,   TumCG?, 1,   TumCG↓, 161,   TumCG↑, 5,   TumCG↝, 2,   TumCG∅, 1,   TumCP↓, 211,   TumCP↑, 7,   TumCP∅, 3,   Wnt?, 1,   Wnt↓, 27,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

Alix/AIP‑1↓, 1,   AntiAg↑, 4,   AP-1↓, 7,   ATPase↓, 1,   ATPase↑, 1,   AXL↓, 3,   BACH1↑, 1,   CA↓, 1,   Ca+2↓, 8,   Ca+2↑, 45,   Ca+2↝, 5,   i-Ca+2?, 1,   i-Ca+2↓, 1,   i-Ca+2↑, 3,   CAFs/TAFs↓, 2,   Cdc42↓, 2,   Cdc42↑, 1,   Chl↑, 1,   Chl∅, 1,   CTNNB1↓, 1,   E-cadherin↓, 3,   E-cadherin↑, 25,   EMT↓, 44,   EMT↑, 1,   EpCAM↓, 1,   F-actin↓, 1,   FAK↓, 10,   p‑FAK↓, 2,   p‑FAK↑, 1,   FOSB↑, 1,   GLI2↓, 3,   hnRNPA1↓, 1,   ITGA1∅, 1,   ITGA5∅, 1,   ITGB1↓, 1,   ITGB1∅, 1,   ITGB3↓, 1,   ITGB3∅, 1,   ITGB4∅, 1,   KRAS↓, 2,   LEF1↓, 2,   LRP1↓, 1,   MALAT1↓, 1,   MET↓, 2,   p‑MET↓, 1,   MMP1↓, 6,   MMP13↓, 1,   MMP2↓, 52,   MMP2↑, 1,   MMP2∅, 1,   proMMP2↓, 1,   MMP3↓, 3,   MMP7↓, 4,   MMP9↓, 60,   MMP9↑, 2,   MMP9∅, 1,   MMPs↓, 20,   MTA1↓, 1,   MUC1↑, 1,   N-cadherin↓, 9,   N-cadherin↑, 1,   NEDD9↓, 1,   p‑p44↓, 1,   PAK1↓, 3,   PAK1↑, 1,   PDGF↓, 3,   Rac1↓, 1,   Rho↓, 5,   ROCK1↓, 2,   Slug↓, 4,   Smad1↓, 1,   SMAD3↓, 2,   Snail?, 1,   Snail↓, 16,   SPARC↑, 1,   TET1?, 1,   TET1↑, 2,   TGF-β↓, 5,   TGF-β1↓, 2,   TIMP1↓, 1,   TIMP1↑, 2,   TIMP2↓, 1,   TIMP2↑, 6,   TRIB3↑, 1,   TSC1↑, 1,   TSP-1↑, 2,   TumCA↓, 2,   TumCI?, 1,   TumCI↓, 62,   TumCI↑, 1,   TumCMig↓, 66,   TumCMig↑, 2,   TumMeta↓, 62,   TumMeta↑, 5,   TumPF↓, 1,   Twist↓, 10,   TXNIP↑, 1,   Tyro3↓, 1,   uPA↓, 9,   uPAR↓, 2,   Vim↓, 16,   Vim↑, 1,   Zeb1↓, 8,   ZEB2↓, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 39,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 91,   angioG↑, 4,   angioG∅, 1,   CD31/PECAM-1↓, 1,   EGR1↑, 1,   Endoglin↑, 1,   eNOS↑, 1,   HIF-1↓, 1,   Hif1a↓, 48,   Hif1a↑, 3,   Hypoxia↓, 1,   LOX1↓, 1,   NO↓, 1,   NO↑, 8,   PHDs↓, 1,   VCAM-1↓, 2,   VEGF↓, 65,   VEGFR1↓, 3,   VEGFR2/KDR/Flk1↓, 5,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 2,   BBB↑, 9,   BBB∅, 1,   CellMemb↓, 1,   CellMemb↑, 6,   CLDN1↓, 2,   CLDN1↑, 1,   CLDN2↓, 1,   CLDN2↑, 1,   CTR1↑, 1,   EPR↓, 1,   EPR↑, 19,   EPR↝, 1,   GLUT1↓, 15,   GLUT1↑, 1,   GLUT2↓, 1,   GLUT3↓, 2,   GLUT4↓, 3,   IBI↑, 2,   KCNH2/hERG↓, 1,   LAT↓, 1,   MMP?, 1,   MMP↓, 198,   MMP↑, 1,   MPT↑, 11,   NHE1↓, 2,   OATPs↓, 1,   OCLN↑, 1,   SLC12A5↓, 2,   SMCT1∅, 1,   sonoP↑, 2,   TJ↓, 1,   TJ↑, 1,   TRPM7↓, 2,   TRPV1↑, 5,   VGCC↑, 1,   VGSC↑, 1,   ZO-1↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD14↓, 1,   CD4+↓, 1,   CD4+↑, 2,   CD44↓, 12,   CD47↓, 1,   CD8+↑, 9,   cDC2↓, 4,   cGAS–STING↑, 1,   COX1↓, 4,   COX2/PTGS2↓, 48,   COX2/PTGS2↑, 5,   CR3↝, 1,   CXCR2↓, 1,   CXCR4↓, 11,   DCells↑, 1,   Dectin1↝, 1,   DR4↑, 6,   DR4∅, 1,   DR6↑, 1,   Eos↑, 1,   Gal1↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   e-HMGB1↑, 1,   ICAM-1↓, 3,   IFN-γ↓, 1,   IFN-γ↑, 5,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 3,   IL1↑, 2,   IL10↓, 3,   IL10↑, 2,   IL12↓, 1,   IL12↑, 1,   IL17↑, 1,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 12,   IL1β↑, 1,   IL2↓, 2,   IL2↑, 6,   IL4↓, 3,   IL6↓, 25,   IL6↑, 1,   IL7↓, 1,   IL8↓, 6,   IL8↑, 1,   Imm↑, 36,   Imm↝, 3,   Inflam↓, 33,   Inflam↑, 1,   IRAK4↓, 1,   pol-M1↑, 1,   pol-M1↝, 1,   M2 MC↓, 3,   pol-M2 MC↓, 1,   MCP1/CCL2↓, 3,   MIP2↓, 1,   Neut↓, 1,   NF-kB↓, 105,   NF-kB↑, 5,   p‑NF-kB↓, 1,   p‑NF-kB↑, 1,   NK cell↑, 15,   NLRP3↓, 2,   NLRP3↑, 3,   p50↓, 1,   p65↓, 7,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 12,   PD-L1↑, 4,   PDT+↓, 1,   PGE2↓, 13,   PSA↓, 13,   RANTES↓, 1,   SOCS1↑, 1,   T-Cell↑, 2,   T-Cell↝, 1,   TCF↓, 3,   TCF↝, 1,   TLR1↑, 1,   TLR2↓, 1,   TLR4↓, 5,   TNF-α↓, 19,   TNF-α↑, 2,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRAF1↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

ADAM17↓, 1,   GFAP↓, 1,   pH↑, 7,   pH↝, 2,   pH∅, 1,   e-pH↓, 1,   e-pH↑, 6,   i-pH↓, 1,   TAMS↑, 1,   Temp↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

6IL↑, 1,   ACTH↓, 1,   AR↓, 19,   AR↑, 1,   AR↝, 1,   AR-FL↓, 1,   AR-V7↑, 1,   CYP11A1↓, 1,   CYP19↓, 1,   CYP24A1↓, 1,   ER-α36↓, 1,   ER(estro)↓, 2,   Estro↝, 1,   FKBP5↓, 1,   GR↓, 1,   Leptin↓, 1,   PPARα↓, 1,   PPARγ↓, 1,   PPARγ↑, 3,   RANKL↓, 1,   SRC3↓, 1,   SXR↑, 1,   VDR↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCC2↓, 1,   BioAv↓, 49,   BioAv↑, 64,   BioAv↝, 12,   BioAv∅, 1,   BioEnh?, 1,   BioEnh↑, 10,   CBR1↓, 1,   chemoR↓, 2,   ChemoSen?, 1,   ChemoSen↓, 6,   ChemoSen↑, 209,   ChemoSen↝, 1,   CompStab↓, 3,   CompStab↑, 4,   CompStab↝, 1,   CYP1A1↓, 2,   CYP1A1↑, 1,   DDS↑, 10,   Dose?, 16,   Dose↓, 8,   Dose↑, 22,   Dose⇅, 1,   Dose↝, 153,   Dose∅, 29,   DrugR↓, 1,   eff?, 5,   eff↓, 440,   eff↑, 818,   eff⇅, 4,   eff↝, 143,   eff∅, 26,   GSTA1↓, 2,   GSTZ1↓, 1,   GSTZ1↝, 1,   GSTZ1∅, 1,   Half-Life↓, 16,   Half-Life↑, 9,   Half-Life↝, 13,   Half-Life∅, 2,   MDR1↓, 6,   MRP↓, 2,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 21,   P-gp/ABCB1∅, 1,   P450↓, 2,   RadioS↓, 1,   RadioS↑, 81,   RadioS↝, 1,   RadioS∅, 1,   selectivity?, 2,   selectivity↓, 3,   selectivity↑, 199,   selectivity↝, 1,   selectivity∅, 2,   Synergy↑, 132,   Synergy∅, 1,   TET2↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AFP?, 1,   AFP↓, 3,   ALAT↓, 2,   ALAT∅, 1,   ALB∅, 1,   ALP↓, 2,   AR↓, 19,   AR↑, 1,   AR↝, 1,   ascitic↓, 1,   AST↓, 2,   AST∅, 1,   BG↓, 6,   BMD↑, 2,   BP↓, 1,   BRAF↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CA125↓, 1,   CA125∅, 1,   CA19-9↓, 1,   CEA↓, 3,   CRP↓, 2,   CRP∅, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 24,   EGFR↑, 2,   p‑EGFR↓, 1,   EZH2↓, 1,   Ferritin↓, 5,   Ferritin↑, 1,   Hcy/homoC↓, 4,   Hcy/homoC↝, 1,   HER2/EBBR2↓, 8,   HOMA↓, 1,   hTERT/TERT↓, 7,   IL6↓, 25,   IL6↑, 1,   KeyT↑, 1,   KRAS↓, 2,   LDH?, 1,   LDH↓, 8,   LDH↑, 4,   LDH↝, 1,   i-LDH↓, 1,   Myc↓, 5,   NOS2↑, 1,   NSE↓, 1,   PD-L1↓, 12,   PD-L1↑, 4,   PSA↓, 13,   TP53↓, 2,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiCan↓, 3,   AntiCan↑, 80,   AntiCan∅, 1,   AntiDiabetic↑, 1,   antiNeop↑, 4,   AntiTum↓, 3,   AntiTum↑, 34,   AntiTum⇅, 1,   cachexia↓, 2,   cardioP↑, 11,   CardioT↓, 1,   CardioT↑, 2,   CardioT↝, 1,   chemoP↑, 40,   chemoP↝, 1,   chemoPv↑, 19,   ChemoSideEff↓, 15,   cognitive↑, 5,   fatigue↓, 3,   hepatoP↓, 1,   hepatoP↑, 8,   memory↑, 2,   motorD↑, 1,   Mucositis↓, 1,   MusCon↓, 2,   neuroP↑, 7,   NKG2D↑, 1,   NP/CIPN↓, 1,   NP/CIPN↑, 2,   OS?, 2,   OS↑, 65,   OS↝, 1,   OS∅, 1,   PARP16↓, 1,   PFS?, 1,   PFS↑, 3,   QoL↑, 12,   QoL∅, 3,   radioP↑, 20,   radioP↝, 1,   Remission↑, 4,   RenoP↑, 4,   Risk↓, 35,   Risk↑, 1,   Risk∅, 4,   Sleep↑, 1,   Strength∅, 1,   toxicity↓, 51,   toxicity↑, 8,   toxicity⇅, 1,   toxicity↝, 25,   toxicity∅, 8,   TumVol↓, 58,   TumW↓, 29,   Weight↓, 1,   Weight↑, 7,   Weight∅, 5,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiP↑, 2,   Bacteria↓, 4,   Dectin1↝, 1,   GutMicro↑, 13,   GutMicro↝, 3,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 4,  
Total Targets: 1245

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 10,   antiOx↑, 99,   mt-antiOx↑, 1,   ARE↑, 2,   Bil↓, 1,   Catalase↓, 1,   Catalase↑, 37,   Copper↓, 1,   CoQ10↑, 1,   DPPH↓, 1,   Fenton↓, 3,   GPx↑, 26,   GPx1↑, 1,   GPx4↓, 1,   GPx4↑, 3,   GPx4∅, 1,   GSH↓, 3,   GSH↑, 48,   GSR↑, 4,   GSTs↑, 8,   H2O2↓, 5,   H2O2↑, 1,   HDL↓, 1,   HDL↑, 5,   HDL∅, 2,   HO-1?, 1,   HO-1↓, 1,   HO-1↑, 28,   HO-1↝, 1,   HO-1∅, 1,   hyperG↓, 1,   Iron↓, 3,   Keap1↓, 2,   Keap1↑, 1,   lipid-P↓, 33,   lipid-P↑, 1,   mt-lipid-P↓, 1,   MDA↓, 30,   MDA↑, 1,   MDA∅, 1,   MPO↓, 5,   MPO↑, 1,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 7,   Nrf1↑, 1,   NRF2↓, 4,   NRF2↑, 51,   NRF2⇅, 1,   NRF2∅, 1,   Prx↑, 1,   RNS↓, 5,   ROS?, 4,   ROS↓, 132,   ROS↑, 14,   ROS⇅, 3,   ROS↝, 1,   ROS∅, 7,   mt-ROS↓, 1,   mt-ROS↑, 2,   selenoP↑, 4,   SOD↓, 3,   SOD↑, 59,   SOD1↑, 2,   TAC↑, 7,   TBARS↓, 4,   Trx↑, 2,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 4,   VitE↓, 1,   VitE↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FPN↑, 1,   IronCh↑, 6,   IronCh↝, 1,   Mets↝, 1,   NCOA4↝, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   compII↑, 1,   compIII↓, 1,   compIII↑, 1,   DRP1/DNM1L↑, 1,   ETC↓, 1,   ETC↑, 1,   FIS1↓, 1,   FIS1↑, 1,   Insulin↓, 3,   Insulin↑, 1,   mitResp↑, 2,   mtDam↓, 6,   OCR↑, 1,   mt-OCR↑, 1,   OXPHOS↑, 1,   PGC-1α↑, 4,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12-HETE↓, 1,   12LOX↓, 3,   5-HETE↓, 1,   5LO↓, 3,   ACSL4∅, 1,   adiP↓, 1,   adiP↑, 2,   ALAT↓, 15,   ALAT∅, 1,   AMPK↓, 1,   AMPK↑, 6,   ATP↓, 3,   ATP↑, 9,   BHB↑, 1,   cAMP↑, 2,   DHA↑, 1,   ECAR↓, 1,   ECAR↑, 1,   Eic↓, 1,   mt-FAO↑, 1,   glucose↓, 4,   glucose↑, 1,   GlucoseCon↑, 4,   Glycolysis↓, 1,   GSK‐3β↓, 4,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   p‑GSK‐3β↑, 1,   KeyT↑, 4,   lactateProd↓, 1,   LDL↓, 14,   lipidLev↓, 1,   NAD↑, 1,   NADH:NAD↑, 1,   NADPH↓, 2,   NADPH↑, 3,   PKM2↓, 2,   SCD1↓, 1,   SIRT1↓, 1,   SIRT1↑, 8,   SIRT2↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 15,   Apoptosis∅, 2,   ASK1↓, 1,   BAX↓, 6,   BAX↑, 2,   Bax:Bcl2↓, 2,   Bcl-2↓, 2,   Bcl-2↑, 3,   Bcl-2∅, 1,   Bcl-xL↓, 1,   Bcl-xL↑, 1,   Casp12↓, 2,   Casp3↓, 16,   Casp3↑, 2,   Casp3∅, 1,   cl‑Casp3↓, 2,   cl‑Casp8↑, 1,   Casp9↓, 6,   Casp9↑, 1,   Cyt‑c↓, 5,   Cyt‑c↑, 3,   Cyt‑c∅, 3,   Ferroptosis↓, 4,   GranB/GZMB↓, 1,   HEY1↑, 1,   iNOS↓, 13,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 1,   p38↑, 2,   p‑p38↓, 1,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 7,   e-Akt↑, 1,   AKT1↓, 1,   Akt2↓, 1,   AMPKα↑, 1,   CREB↑, 1,   ERK↓, 1,   ERK↑, 4,   e-ERK↑, 1,   HCAR2↑, 1,   IKKα↓, 1,   IκB?, 1,   JAK2↑, 1,   JNK↓, 4,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 7,   MAPK↑, 6,   Mst1↓, 1,   mTOR↓, 5,   mTOR↑, 1,   mTOR↝, 1,   p‑mTOR↓, 1,   p‑mTOR↑, 1,   PI3K↓, 4,   PI3K↑, 4,   PKA↑, 2,   PKCδ?, 1,   PKCδ↓, 1,   PKCδ↑, 1,   PP2A↑, 1,   PTEN↓, 2,   RAS↓, 1,   STAT↓, 1,   STAT3↓, 3,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 4,   ATF4↓, 1,   FOXO↑, 1,   HDAC↓, 1,   other?, 4,   other↓, 9,   other↑, 27,   other↝, 44,   SOX9↑, 1,   tumCV↓, 1,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   cl‑eIF2α↑, 1,   ER Stress↓, 6,   ER Stress↑, 1,   GRP78/BiP↓, 4,   GRP78/BiP↑, 1,   HSF1↑, 2,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 2,   HSP70/HSPA5↝, 1,   HSPs↑, 3,   IRE1↓, 2,   p‑PERK↑, 1,   UPR↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

CTSZ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   MitoP↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 13,   DNAdam↑, 2,   DNArepair↑, 3,   P53↑, 2,   PARP↓, 1,   γH2AX↓, 1,   p‑γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   E2Fs↑, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   Choline↑, 1,   Diff↑, 4,   Diff↝, 1,   FGF↑, 1,   IGF-1↓, 2,   IGFBP3↑, 1,   neuroG↑, 1,   NOTCH↑, 1,   TumCP↓, 2,   tyrosinase↓, 1,   Wnt↑, 2,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 10,   ARG1/2↑, 1,   Ca+2↓, 3,   Ca+2↑, 7,   Ca+2↝, 4,   cal2↓, 1,   Cartilage↑, 1,   COL1↓, 1,   COL2A1↑, 1,   E-cadherin↑, 1,   EMT↓, 2,   EMT↑, 1,   F-actin↑, 1,   FAK↑, 2,   MLC2/MYL9↝, 1,   MMP13↓, 1,   MMP2↓, 2,   MMP2↑, 2,   MMP9↓, 11,   MMP9↑, 2,   MMPs↓, 1,   MMPs↑, 1,   PAI-1/SERPINE1↓, 1,   SMAD3↓, 2,   Snail↑, 1,   TG2/TGase↓, 1,   TGF-β↓, 1,   TGF-β↑, 4,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   Twist↑, 1,   Vim↓, 1,   Vim↑, 1,   α-SMA↓, 1,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 2,   CD31/PECAM-1↑, 1,   eNOS↑, 1,   Hif1a↓, 2,   Hif1a↑, 2,   Hif1a∅, 1,   NO?, 1,   NO↓, 13,   NO↑, 4,   VCAM-1↓, 2,   VEGF↓, 2,   VEGF↑, 5,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 37,   BBB↝, 1,   BBB∅, 2,   CellMemb↑, 1,   CLDN1↓, 1,   CLDN1↑, 1,   CLDN1↝, 1,   EPR↑, 1,   GastroP↑, 5,   GLUT1↑, 2,   GLUT3↑, 1,   GLUT4↑, 1,   IBI↑, 1,   ketosis↑, 1,   MMP↓, 4,   MMP↑, 10,   MMP↝, 1,   MMP∅, 2,   MPT↑, 1,   OCLN↝, 1,   TJ↓, 1,   TJ↑, 2,   TRPV3↑, 1,   VGCC↑, 2,   VGCC⇅, 1,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 1,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD14↑, 1,   CD25+↑, 1,   CD4+↑, 3,   CD8+↑, 2,   COX1↓, 2,   COX2/PTGS2↓, 22,   CXCR4↓, 1,   Eos↓, 1,   FOXP3↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   IFN-γ↓, 3,   IFN-γ↑, 2,   IgE↓, 1,   IL1↓, 2,   IL10?, 1,   IL10↓, 2,   IL10↑, 9,   IL10∅, 1,   IL17↓, 7,   IL17∅, 1,   IL18↓, 1,   IL1α↓, 1,   IL1β↓, 26,   IL2↓, 2,   IL22↓, 1,   IL23↓, 1,   IL4↓, 1,   IL4↑, 3,   IL4∅, 1,   IL5↑, 1,   IL6↓, 33,   IL6↑, 4,   IL8↓, 3,   Imm↑, 18,   Imm⇅, 1,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 130,   Inflam↑, 2,   IRF3↓, 1,   LPS↓, 2,   M2 MC↑, 1,   MCP1/CCL2↓, 4,   MCP1/CCL2↑, 1,   MIP‑1α/CCL3↓, 1,   MyD88↓, 2,   NeuroI↓, 1,   NF-kB↓, 31,   NF-kB↑, 2,   NK cell↑, 1,   NLRP3↓, 5,   NLRP3↑, 1,   p65↓, 1,   PAF↓, 1,   PGE2↓, 9,   PSA↓, 1,   TLR1↓, 1,   TLR2↓, 2,   TLR4↓, 4,   TNF-α↓, 48,   TNF-α↑, 1,   Treg lymp↑, 1,   Treg lymp↝, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,   Temp↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 1,   5HT↓, 1,   5HT↑, 2,   Ach?, 1,   Ach↑, 6,   AChE↓, 24,   AChE∅, 2,   ADAM10↑, 1,   BChE↓, 9,   BDNF↑, 15,   BrainVol↑, 1,   BrainVol∅, 1,   ChAT↑, 1,   GABA↑, 3,   MAOA↓, 2,   NMDAR↑, 1,   PSD95↑, 1,   SNAP25↑, 1,   TrkB↑, 1,   β-Endo↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   APP↓, 4,   Aβ↓, 32,   Aβ42↓, 1,   BACE/β-secretase↓, 8,   IDE↑, 1,   tau↓, 4,   p‑tau↓, 8,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

BNP↓, 1,   GPER↑, 1,   GR↑, 2,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv?, 1,   BioAv↓, 36,   BioAv↑, 66,   BioAv⇅, 1,   BioAv↝, 24,   BioEnh↑, 8,   ChemoSen↑, 1,   CompStab↓, 1,   CompStab↑, 5,   CompStab↝, 2,   CYP1A1↓, 1,   CYP2C19↓, 1,   CYP2C8↓, 1,   CYP2C9↓, 1,   CYP2D6↓, 1,   CYP2E1↓, 1,   CYP3A4↓, 2,   DDS↑, 1,   Dose?, 2,   Dose↓, 8,   Dose↑, 7,   Dose⇅, 1,   Dose↝, 93,   Dose∅, 2,   eff?, 2,   eff↓, 37,   eff↑, 262,   eff↝, 36,   eff∅, 2,   GSTA1↓, 2,   GSTA1↑, 1,   Half-Life↓, 5,   Half-Life↑, 7,   Half-Life⇅, 1,   Half-Life↝, 14,   Half-Life∅, 3,   P-gp/ABCB1↓, 3,   P450↓, 1,   selectivity↑, 2,   Synergy↑, 13,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 15,   ALAT∅, 1,   ALP↓, 4,   ALP↑, 1,   anemia↓, 1,   AST↓, 15,   AST∅, 1,   BG↓, 1,   Bil↓, 1,   BloodF↑, 3,   BMD↑, 7,   BP↓, 16,   BP∅, 1,   BUN↓, 3,   creat↓, 6,   CRP↓, 7,   Ferritin↓, 1,   FEV1↑, 2,   Hcy/homoC↓, 2,   HemoG↑, 1,   hs-CRP↓, 1,   IL6↓, 33,   IL6↑, 4,   KeyT↑, 4,   LDH↓, 6,   LDH↑, 1,   LDH∅, 1,   NLR↓, 1,   NOS2↓, 2,   PEF↑, 1,   PSA↓, 1,   PV↓, 1,   RBC↑, 1,   SpO2↑, 1,   TC↓, 1,   TMAO↑, 3,   TMAO⇅, 1,   UFR?, 1,   UFR↑, 1,   UR↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 5,   antiAll↑, 15,   antiAll∅, 1,   AntiArt↑, 7,   AntiCan↑, 11,   antiD↓, 1,   AntiDiabetic↑, 18,   antiPs↑, 1,   AntiTum↓, 1,   AntiTum↑, 3,   BOLD↑, 2,   Bone Healing↑, 1,   cachexia↓, 1,   cardioP↑, 36,   CardioT↓, 3,   chemoP↑, 10,   chemoPv↑, 5,   cognitive?, 1,   cognitive↓, 3,   cognitive↑, 71,   cognitive∅, 1,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 1,   hepatoP↑, 31,   IPSS↝, 1,   Learn↑, 1,   memory↓, 2,   memory↑, 41,   memory∅, 1,   Mood?, 1,   Mood↑, 5,   motorD↓, 1,   motorD↑, 13,   MusCon↓, 1,   Nausea↓, 1,   neuroP?, 1,   neuroP↑, 73,   Obesity↓, 8,   OS↓, 1,   OS↑, 5,   Pain↓, 9,   PDE4↓, 1,   QoL↑, 1,   radioP↑, 4,   RenoP↑, 15,   Risk↓, 8,   Risk↑, 2,   Sleep↑, 5,   Strength↑, 2,   Stress↓, 3,   Stroke↓, 8,   toxicity?, 3,   toxicity↓, 78,   toxicity↑, 7,   toxicity↝, 11,   toxicity∅, 26,   Vomit↓, 1,   Weight↓, 4,   Weight↑, 1,   Weight↝, 1,   Weight∅, 1,   Wound Healing↓, 1,   Wound Healing↑, 11,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 7,   AntiFungal↑, 4,   AntiP↓, 1,   AntiP↑, 2,   AntiViral↑, 13,   Bacteria↓, 26,   Diar↓, 1,   Dysb↓, 1,   GutMicro↑, 15,   GutMicro↝, 1,   Inf↓, 1,   Sepsis↓, 7,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 2,   Ingr↝, 5,   Phen↑, 1,  
Total Targets: 611

Scientific Paper Hit Count for: eff, efficacy
64 Silver-NanoParticles
59 Magnetic Fields
33 Sulforaphane (mainly Broccoli)
28 Thymoquinone
27 Curcumin
26 immunotherapy
26 Shikonin
25 Chemotherapy
25 Vitamin C (Ascorbic Acid)
23 chitosan
22 Selenite (Sodium)
21 Radiotherapy/Radiation
21 Baicalein
21 Selenium NanoParticles
20 Piperlongumine
19 Copper and Cu NanoParticles
19 EGCG (Epigallocatechin Gallate)
18 Artemisinin
17 Magnetic Field Rotating
16 Melatonin
16 Berberine
16 Exercise
15 Chlorogenic acid
14 Apigenin (mainly Parsley)
14 Luteolin
14 Phenylbutyrate
14 Caffeic acid
14 Capsaicin
14 Resveratrol
14 Quercetin
14 Gambogic Acid
13 Selenium
13 diet FMD Fasting Mimicking Diet
12 Gold NanoParticles
12 Citric Acid
12 Ashwagandha(Withaferin A)
12 Propolis -bee glue
12 Folic Acid, Vit B9
12 Dichloroacetate
12 Hydrogen Gas
11 3-bromopyruvate
11 Cisplatin
11 Betulinic acid
11 Ivermectin
11 Lycopene
11 Phenethyl isothiocyanate
10 Vitamin D3
10 Choline
10 diet Methionine-Restricted Diet
10 Disulfiram
10 Honokiol
9 Auranofin
9 Metformin
9 borneol
9 Electrical Pulses
9 Formononetin
9 Bicarbonate(Sodium)
8 Photodynamic Therapy
8 Fenbendazole
8 SonoDynamic Therapy UltraSound
8 chaetocin
8 doxorubicin
8 Fisetin
8 Hyperthermia
8 Plumbagin
8 Rosmarinic acid
7 Coenzyme Q10
7 Docetaxel
7 Boron
7 buckwheat sprouts
7 Ellagic acid
7 Chrysin
7 Dandelion Root
7 Juglone
7 VitK3,menadione
7 mebendazole
7 salinomycin
6 Alpha-Lipoic-Acid
6 beta-glucans
6 isoorientin
6 Carnosic acid
6 Celastrol
6 Vitamin B12
6 Chlorophyllin
6 Docosahexaenoic Acid
6 Eugenol
6 MCT oil
6 Flaxseed/Linseed
6 Ginger/6-Shogaol/Gingerol
6 isoquercitrin
6 MCT, metronomic chemo
6 Parthenolide
6 Vitamin K2
5 Astragalus
5 Akkermansia
5 Bevacizumab (brand Avastin)
5 Ascorbyl Palmitate
5 Lutein
5 Bifidobacterium
5 Boswellia (frankincense)
5 Piperine
5 Silymarin (Milk Thistle) silibinin
5 Cynaropicrin
5 Diclofenac
5 eicosapentaenoic acid
5 diet Plant based
5 Lemongrass Extract/Citral
5 Ginkgo biloba-EGb 761
5 Gossypol/AT-101
5 Isoliquiritigenin
5 Licochalcone A
5 Moringa oleifera
5 Nimbolide
5 Spermidine
5 Urolithin
4 chemodynamic therapy
4 EMF
4 Cynara scolymus/Globe Artichoke/Artichoke Extract
4 Allicin (mainly Garlic)
4 almonertinib
4 Berbamine
4 α-Bisabolol / Chamomile oil
4 Butyrate
4 capecitabine
4 Carvacrol
4 Cat’s Claw
4 Centella asiatica / Gotu kola → asiaticoside
4 CUSP9
4 diet Short Term Fasting
4 Echinacea
4 Kaempferol
4 phytic acid, Inositol hexakisphosphate
4 Fucoidan
4 Ginkgolide B
4 Ginseng
4 HydroxyCitric Acid
4 Magnolol
4 Isobavachalcone
4 Matrine
4 methylseleninic acid
4 Methylsulfonylmethane
4 Propyl gallate
4 Pterostilbene
4 Terpinen-4-ol / Tea Tree Oil
4 Whole Body Vibration
3 cetuximab
3 5-fluorouracil
3 Anthocyanins
3 Aspirin
3 Atorvastatin
3 Aloe anthraquinones
3 bempedoic acid
3 beta-carotene(VitA)
3 Zeaxanthin
3 Bortezomib
3 Bullatacin
3 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
3 Thymol-Thymus vulgaris
3 Cannabidiol
3 Chocolate
3 Cichoric acid / Chicoric acid
3 Crocetin
3 Cysteamine
3 erastin
3 Gallic acid
3 Gamma-aminobutyric acid
3 Ginkgo biloba
3 Lemon Balm/Melissa officinalis
3 Germanium Organic/Ge-132 / propagermanium (organogermanium)
3 Gemcitabine (Gemzar)
3 Hibiscus sabdariffa
3 HydroxyTyrosol
3 iodine
3 Inulin Prebiotic
3 isoflavones
3 Licorice
3 Lactoferrin/Talactoferrin
3 nicotinamide adenine dinucleotide
3 Radio Frequency
3 Sulfasalazine
3 Taurine
3 Vitamin B1/Thiamine
2 1,8-Cineole
2 2-DeoxyGlucose
2 Glucose
2 Zinc
2 Andrographis
2 Anti-oxidants
2 Vitamin A, Retinoic Acid
2 Aromatherapy
2 Astaxanthin
2 Arsenic trioxide
2 Baicalin
2 Huperzine A/Huperzia serrata
2 Beta-Caryophyllene
2 Bufalin/Huachansu
2 temozolomide
2 probiotics
2 brusatol
2 Vitexin
2 Isovitexin
2 Rutin
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Caffeine
2 Calcium
2 Celecoxib
2 Hydroxycinnamic-acid
2 Calorie Restriction Mimetics
2 Cyclopamine
2 Dichloroacetophenone(2,2-)
2 Deguelin
2 Date Fruit Extract
2 diet Ketogenic
2 Oxygen, Hyperbaric
2 D-limonene
2 statins
2 Emodin
2 Vitamin E
2 ferumoxytol
2 Paclitaxel/Taxol
2 SDG/lignans
2 tamoxifen
2 Garcinol
2 Geldanamycin
2 γ-linolenic acid (Borage Oil)
2 Grapeseed extract
2 Orlistat
2 hydroxychloroquine
2 Helleborus niger extracts – Christmas Rose
2 Hyperoside
2 itraconazole
2 Potassium
2 lambertianic acid
2 Lapachol
2 Methylene blue
2 Methyl Jasmonate
2 Magnesium
2 Mistletoe/Viscum album Extracts
2 Naringin
2 Marjoram (Origanum majorana)
2 Rauwolfia serpentina/Indian Snakeroot
2 Aflavin-3,3′-digallate
2 tetrathiomolybdate
2 Ursolic acid
1 5-Aminolevulinic acid
1 Anzaroot, Astragalus fasciculifolius Bioss
1 wortmannin
1 Resiquimod
1 Aidi injection
1 Acetyl-l-carnitine
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Amodiaquine
1 DTS(dibenzyl trisulphide) from Anamu
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Sorafenib (brand name Nexavar)
1 Trastuzumab
1 Biochanin A
1 Brucea javanica
1 Bacopa monnieri
1 Bromelain
1 Bruteridin(bergamot juice)
1 urea
1 Cannabichromene
1 Beta‐Lapachone
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 irinotecan
1 Carvone
1 Polyphenols
1 Black phosphorus
1 Cucurbitacin
1 gefitinib, erlotinib
1 Dasatinib/Phyrago
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 Dipyridamole
1 Protocatechuic acid
1 PXD, phenoxodiol
1 Eurycomanone
1 flavonoids
1 Flickering Light Stimulation
1 Flaxseed Oil
1 Galloflavin
1 verapamil
1 Salvia officinalis
1 Germanium inorganic
1 Geraniol
1 Germanium-Spirogermanium
1 Ginkgetin
1 Glabrescione B
1 Graviola
1 High-Ozonide Oil
1 Indole-3-carbinol
1 entinostat
1 Recombinant Methioninase
1 Lactobacillus
1 Laetrile B17 Amygdalin
1 Lapatinib
1 low dose naltrexone
1 Lecithin
1 Linalool
1 Mung Bean Sprouts
1 Modified Citrus Pectin
1 carboplatin
1 Methylglyoxal
1 magnetic nanoparticles
1 Mushroom Lion’s Mane
1 Mushroom Reishi
1 Myricetin
1 No Product/Mechanism Only
1 Oleocanthal
1 Peppermint
1 sericin
1 Phosphatidylserine
1 Pumpkin Seed Oil / Cucurbita pepo
1 Tamsulosin
1 enzalutamide
1 Rhein
1 Oxaliplatin
1 α-Santalol/Sandalwood oil
1 Scoulerine
1 polyethylene glycol
1 Iron
1 Squalene
1 Glutathione
1 Sutherlandioside D
1 Triphala
1 triptolide
1 Tumor Treating Fields
1 Turmerones
1 Vitamin B3,Niacin
1 Vitamin B5,Pantothenic Acid
1 Vitamin B6,pyridoxine
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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