Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
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Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
7930- H2,    Hydrogen-rich water alleviates asthma airway inflammation by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation
- in-vivo, Asthma, NA
*GutMicro↑, *Inflam↓, *Dose↝, *AirwayM↓, *antiAll↑,
7931- H2,    Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells
- in-vitro, Asthma, NA
*p‑FcεRI↓, *NADPH↓, *H2O2↓, *Dose↝, *antiAll↑,
7932- H2,    Hydrogen Gas Inhalation Alleviates Airway Inflammation and Oxidative Stress on Ovalbumin-Induced Asthmatic BALB/c Mouse Model
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *ROS↓, *TAC↑, *IgE↓, *Dose↝, *NLR↓, *IL4↓, *IL5↓, *IL13↓, *GM-CSF↓, *NO↓, *GPx↑, *Eos↓, *antiAll↑,
2513- H2,    Hydrogen therapy: from mechanism to cerebral diseases
- Review, Stroke, NA
*BBB?, *antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Dose↝,
2527- H2,    The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats
- in-vivo, Wounds, NA
*Dose↝, *SOD↑, *EGF↑, *antiOx↑, *Inflam↓, *Dose↝,
2524- H2,    Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy
- Trial, Var, NA
hepatoP↑, *ALAT↓, *AST↓, Dose↝, Dose↝,
2512- H2,    Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch
- in-vivo, Asthma, NA
*selectivity↑, *lactateProd↓, *ATP↑, *HK2↓, *PFK↓, *Hif1a↓, *PGC-1α↑, *Glycolysis↓, *OXPHOS↑, *Dose↝, *antiAll↑,
2511- H2,    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation
- in-vivo, GBM, U87MG
TumCG↓, OS↑, CD133↓, Ki-67↓, angioG↓, Diff↑, TumCMig↓, TumCI↓, Dose↝, BBB↑, mt-ROS↑,
2509- H2,    Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway
- in-vitro, Endo, AN3CA - in-vivo, Endo, NA
selectivity↑, mt-ROS↑, ROS↑, TumW↓, GSDMD↑, Pyro↑, Dose↝, eff↓, TumVol↓,
2506- H2,    Molecular hydrogen suppresses activated Wnt/β-catenin signaling
- in-vivo, Arthritis, NA
*Wnt↓, *β-catenin/ZEB1↓, *Dose↝,
2505- H2,    Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis
- Trial, CRC, NA
PGC-1α↑, Dose↝, CD8+↑, OS↑,
2504- H2,    Hydrogen gas activates coenzyme Q10 to restore exhausted CD8+ T cells, especially PD-1+Tim3+terminal CD8+ T cells, leading to better nivolumab outcomes in patients with lung cancer
- Trial, Lung, NA
CD8+↑, OS↑, eff↝, CoQ10↑, PDT+↓, PGC-1α↑, Dose↝, *toxicity∅,
2503- H2,    Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report
- Case Report, Lung, NA
TumVol↓, OS↑, Dose↝, Dose↝, CEA↓, CA125↓, CYFRA21-1↓, SIRT1↓, COX2/PTGS2↓, IL1β↓, IL6↓, TNF-α↓, HMGB1↓, NF-kB↓, EP2↓,
2530- H2,    Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases
- Case Report, PSA, NA
eff↑, Dose↝, eff↑, IL6↓, eff↑,
3152- H2,  VitC,  Rad,    Hydrogen and Vitamin C Combination Therapy: A Novel Method of Radioprotection
- in-vitro, Nor, HUVECs - in-vivo, NA, NA
AntiTum↑, OS↑, QoL↑, TumVol↓, radioP↑, Dose↑, Dose↝, Synergy↑,
7496- H2S,    Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation
- in-vivo, AD, NA
*neuroP↑, *cognitive↑, *p‑tau↓, *Dose↝,
7523- HCA,    Inhibition of ATP Citrate Lyase by Hydroxycitrate-Loaded Exosomes Suppresses the Survival of Lung Adenocarcinoma Cells
- in-vitro, Lung, NA
ACLY↓, BioAv↓, Dose↝, TumCP↓, FASN↓, IDH1↓, Apoptosis↑, ROS↑, Half-Life↝,
1631- HCA,    An overview of the safety and efficacy of a novel, natural(-)-hydroxycitric acid extract (HCA-SX) for weight management
- Review, Obesity, NA
*ACLY↓, *toxicity∅, *Dose∅,
1645- HCAs,    Chapter 8 - Hydroxycinnamic Acids: Natural Sources, Biosynthesis, Possible Biological Activities, and Roles in Islamic Medicine
- Review, Nor, NA
Dose∅, ROS⇅, Dose∅,
1644- HCAs,  PBG,    Artepillin C (3,5-diprenyl-4-hydroxycinnamic acid) sensitizes LNCaP prostate cancer cells to TRAIL-induced apoptosis
- in-vitro, Pca, LNCaP
NF-kB↓, TRAILR↑, Casp8↑, Casp3↑, MMP↓, Dose?,
1643- HCAs,    Mechanisms involved in the anticancer effects of sinapic acid
- Review, Var, NA
*BioAv↓, *toxicity↓, Dose∅, ROS⇅, ROS↑, Igs↑, TumCCA↑, TumAuto↑, eff↑, angioG↓, TumCI↓, TumMeta↓, EMT↓, Vim↓, MMP9↓, MMP2↓, Snail↓, E-cadherin↑, p‑Akt↓, GSK‐3β↓, TumCP↓, ChemoSen↑,
1641- HCAs,    Lung cancer induced by Benzo(A)Pyrene: ChemoProtective effect of sinapic acid in swiss albino mice
- in-vitro, Lung, A549 - in-vivo, Lung, NA
AntiCan↑, Igs↓, lipid-P↓, ROS↑, Casp3↑, Casp9↑, ChemoSideEff↓, Dose∅,
7509- HCAs,    Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review
- Review, Nor, NA
*BioAv↓, *Dose↝, *BioAv↝, *BioAv↝, *BioAv↑,
7508- HCAs,    Natural Sources, Pharmacokinetics, Biological Activities and Health Benefits of Hydroxycinnamic Acids and Their Metabolites
- Review, Nor, NA
*Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *BioAv↓, *antiOx↑, *ROS↓, *Inflam↓, *neuroP↑, *cardioP↑, *hepatoP↑,
7506- HCAs,    A Systematic Review and Comprehensive Evaluation of Human Intervention Studies to Unravel the Bioavailability of Hydroxycinnamic Acids
- Review, Nor, NA
*other↝, *BioAv↝, *Half-Life↝, *other↝, *Dose↝, *BioAv↝,
7370- HibSad,    Hibiscus sabdariffa leaf induces apoptosis of human prostate cancer cells in vitro and in vivo
- vitro+vivo, Pca, LNCaP - in-vitro, Pca, PC3 - in-vitro, Pca, DU145
eff↑, Dose↝, Bcl-2↓, Mcl-1↓, BAX↑, Cyt‑c↑, FasL↑, eff↑, TumW↓, TumVol↓, other↝,
7369- HibSad,    Components in aqueous Hibiscus rosa-sinensis flower extract inhibit in vitro melanoma cell growth
- in-vitro, Melanoma, B16-BL6 - in-vitro, Nor, LA25
TumCG↓, selectivity↑, Dose↝, eff↑,
7362- HibSad,    The effect of a water extract and anthocyanins of hibiscus sabdariffa L on paracetamol-induced hepatoxicity in rats
- in-vivo, Nor, NA
*Dose↝, *hepatoP↑,
7357- HibSad,    Hibiscus Anthocyanins Extracts Induce Apoptosis by Activating AMP-Activated Protein Kinase in Human Colorectal Cancer Cells
- in-vitro, CRC, LoVo
Apoptosis↑, AMPK↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑Casp3↑, Dose↝, mtDam↑, MMP↓, Akt↓,
7354- HibSad,    Hibiscus sabdariffa Leaf Extract Inhibits Human Prostate Cancer Cell Invasion via Down-Regulation of Akt/NF-kB/MMP-9 Pathway
- vitro+vivo, Pca, LNCaP
MMP9↓, NF-kB↓, Akt↓, TumVol↓, PI3K↓, *antiOx↑, Dose↝,
7350- HibSad,    Hibiscus polyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathway
- in-vitro, GC, AGS
TumCD↑, DNAdam↑, P53↑, Bcl-2↓, Mcl-1↓, Cyt‑c↑, FasL↑, Fas↑, p38↑, BAX↑, Dose↝, TumCCA↑,
7349- HibSad,    Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract
- Trial, Nor, NA
*Dose↝, *Half-Life↓, *Half-Life↝, *BioAv↓, *antiOx↑, *BioAv↓,
7343- Hne,    Comparative Evaluation of the Potential Antitumor of Helleborus purpurascens in Skin and Breast Cancer
- in-vitro, Melanoma, A431 - in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vitro, Nor, HaCaT - in-vitro, Nor, JB6
*Dose↝, *antiOx↑, selectivity↑, Bcl-2↓, BAD↑, BAX↑,
7466- HNK,  PDT,  MET,    Enhanced integrated therapy for breast cancer employing Honokiol-loaded mesoporous polydopamine nanoparticles in conjunction with photothermal effects and low-dose metformin
- in-vitro, BC, NA
TumCD↓, Dose↝, cl‑Casp3↑, cl‑PARP↑, Apoptosis↑, TumCP↓,
7465- HNK,    Aptamer-modified GSH-degradable honokiol polyprodrug nanoparticles for ovarian cancer-specific targeting therapy
- in-vitro, Ovarian, NA
Dose↝, eff↑,
7461- HNK,    Honokiol: a potent chemotherapy candidate for human colorectal carcinoma
- vitro+vivo, CRC, RKO
Apoptosis↑, Casp↑, Dose↝, OS↑, *Inflam↓, *AntiThr↑, *antiOx↑, *Half-Life↝, TumCG↓,
2079- HNK,    Honokiol Microemulsion Causes Stage-Dependent Toxicity Via Dual Roles in Oxidation-Reduction and Apoptosis through FoxO Signaling Pathway
- in-vitro, Nor, PC12
*toxicity↝, *ROS↓, *ROS↑, *Dose⇅, *BioAv↑, *BioAv↓, *ROS⇅, *SOD↓, *toxicity↑,
2873- HNK,    Honokiol Alleviates Oxidative Stress-Induced Neurotoxicity via Activation of Nrf2
- in-vitro, Nor, PC12
*neuroP↑, *GSH↑, *HO-1↑, *NADPH↑, *Trx1↑, *TrxR1↑, *NRF2↑, *ROS↓, *antiOx↑, *BBB↑, Dose↓,
2864- HNK,    Honokiol: A Review of Its Anticancer Potential and Mechanisms
- Review, Var, NA
TumCCA↑, CDK2↓, EMT↓, MMPs↓, AMPK↑, TumCI↓, TumCMig↓, TumMeta↓, VEGFR2/KDR/Flk1↓, *antiOx↑, *Inflam↓, *BBB↑, *neuroP↑, *ROS↓, Dose↝, selectivity↑, Casp3↑, Casp9↑, NOTCH1↓, cycD1/CCND1↓, cMyc↓, P21?, DR5↑, cl‑PARP↑, P53↑, Mcl-1↑, p65↓, NF-kB↓, ROS↑, JNK↑, NRF2↑, cJun↑, EF-1α↓, MAPK↓, PI3K↓, mTORC1↓, CSCs↓, OCT4↓, Nanog↓, SOX4↓, STAT3↓, CDK4↓, p‑RB1↓, PGE2↓, COX2/PTGS2↓, β-catenin/ZEB1↑, IKKα↓, HDAC↓, HATs↑, H3↑, H4↑, LC3II↑, c-Raf↓, SIRT3↑, Hif1a↓, ER Stress↑, GRP78/BiP↑, cl‑CHOP/DDIT3↑, MMP↓, PCNA↓, Zeb1↓, NOTCH3↓, CD133↓, Nestin↓, ATG5↑, ATG7↑, survivin↓, ChemoSen↑, SOX2↓, OS↑, P-gp/ABCB1↓, Half-Life↓, Half-Life↝, Synergy↑, BioAv↓,
7371- HOO,    Phytochemical characterization of peanut oil and its ozonized form to explore biological activities in vitro
- in-vitro, Colon, NA
Dose↝, AntiBio↑, antiOx↑, AntiCan↑, selectivity↑,
7651- HPT,  Rad,    Hyperthermia inhibits homologous recombination repair and sensitizes cells to ionizing radiation in a time- and temperature-dependent manner
- in-vitro, Var, NA
RadioS↑, DNArepair↓, Dose↑,
7649- HPT,  Rad,    A pilot study of the effects of mild systemic heating on human head and neck tumour xenografts: Analysis of tumour perfusion, interstitial fluid pressure, hypoxia and efficacy of radiation therapy
- in-vivo, Laryn, FaDu
Dose↝, BloodF↑, Hypoxia↓, RadioS?,
7618- HPT,    ESHO 2-85. Hyperthermia as an adjuvant to radiation therapy in the treatment of advanced neck nodes: A randomized multicenter study by the European Society for Hyperthermic Oncology
- Trial, HNSCC, NA
ORR↑, NA↑, NA↑, BioAv↝, Dose↝, Dose↝,
7599- HPT,  Rad,    Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome
- Review, Var, NA
NA↑, RadioS↑, DNArepair↓, Hypoxia↓, EPR↑, LC↑, OS↑, *toxicity↓, Dose↝, BloodF↑, pH↝, Imm↑, HSP70/HSPA5↑,
7621- HPT,  Rad,    Clinical effectiveness of combined whole body hyperthermia and external beam radiation therapy (EBRT) versus EBRT alone in patients with painful bony metastases: A phase III clinical trial study
- Trial, Pca, NA - Trial, BC, NA
Pain↓, Dose↝, CR↑,
7622- HPT,    A Review of the Current Clinical Evidence for Loco-Regional Moderate Hyperthermia in the Adjunct Management of Cancers
- Review, Var, NA
LC↑, OS↑, QoL↑, toxicity↓, Dose↝, Dose↝, ROS↑, DNArepair↓, EPR↑, DNAdam↑, HSP70/HSPA5↑, BloodF↑, Hypoxia↓,
7577- HPT,  Rad,    Randomized trial of hyperthermia and radiation for superficial tumors
- Trial, Var, NA
RadioS↑, eff↑, Dose↝,
7575- HPT,  Rad,  Chemo,  immuno,    From Localized Mild Hyperthermia to Improved Tumor Oxygenation: Physiological Mechanisms Critically Involved in Oncologic Thermo-Radio-Immunotherapy
- Analysis, Var, NA
RadioS↑, ChemoSen↑, Imm↑, BloodF↑, Hypoxia↓, Dose↝, DNArepair↓, e-pH↓,
7574- HPT,  Oxy,    Improvement of tumor oxygenation by mild hyperthermia
- Review, Var, NA
Hypoxia↓, OCR↓, RadioS↑, Synergy↑, Dose↝,
7572- HPT,  Rad,    The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination
- in-vitro, Cerv, HeLa - in-vitro, Laryn, FaDu
RadioS↑, TumCD↑, BRCA2↓, Dose↝, BloodF↑, ROS↑, Imm↑,

Showing Research Papers: 601 to 650 of 1225
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1225

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 5,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 16,   antiOx⇅, 1,   ARE↓, 1,   Bil∅, 1,   Catalase↓, 7,   Catalase↑, 3,   CoQ10↑, 1,   ENOX2↓, 2,   ENOX2↑, 1,   Fenton↑, 3,   GPx↓, 3,   GPx↑, 6,   GPx1↓, 1,   GPx1↑, 1,   GPx4↓, 5,   GSH↓, 28,   GSH↑, 8,   GSH/GSSG↓, 2,   GSR↑, 1,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 10,   mt-H2O2↑, 1,   HO-1↓, 6,   HO-1↑, 5,   HO-2↓, 1,   Iron↑, 3,   i-Iron↓, 1,   lipid-P?, 1,   lipid-P↓, 5,   lipid-P↑, 8,   lipidDe↓, 1,   MDA↓, 3,   MDA↑, 4,   i-MDA↑, 1,   MPO↓, 1,   NADH↓, 1,   NADHdeh?, 1,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 2,   NRF2↓, 9,   NRF2↑, 12,   NRF2↝, 1,   Prx↑, 1,   Prx6↑, 1,   PrxI↓, 1,   ox-PrxI↑, 1,   ROS↓, 19,   ROS↑, 208,   ROS⇅, 6,   ROS↝, 2,   ROS∅, 2,   i-ROS↑, 1,   mt-ROS↑, 11,   SOD↓, 6,   SOD↑, 7,   mt-SOD↑, 1,   SOD1↓, 1,   SOD1↑, 1,   SOD2↓, 3,   SOD2↑, 1,   Thiols↓, 2,   Trx↓, 4,   Trx1↓, 1,   TrxR↓, 13,   TrxR1↓, 2,   TrxR1↑, 1,   uricA↓, 1,   xCT/SLC7A11↓, 3,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FTH1↓, 1,   IronCh↑, 1,   selm↑, 1,   Tf↓, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   CDC2↓, 2,   CDC25↓, 7,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   EGF↓, 1,   ETC↓, 6,   ETC↑, 1,   ETC↝, 1,   HSP60/HSPD1↓, 2,   Insulin↓, 4,   MFN2↑, 1,   mitResp↓, 2,   MKK7↓, 1,   mtDam↓, 1,   mtDam↑, 27,   OCR↓, 7,   OCR↑, 3,   OXPHOS↓, 6,   OXPHOS↑, 6,   OXPHOS↝, 1,   mt-OXPHOS↓, 1,   PDH↓, 1,   p‑PDH↓, 1,   p‑PDH↑, 1,   PGC-1α↑, 3,   PHB↓, 1,   PINK1↑, 1,   SDH↓, 2,   SIRT3↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 3,   5LO↓, 3,   ACC↑, 1,   ACLY↓, 4,   ACSL4↑, 2,   Alanine↓, 1,   ALAT↓, 3,   ALAT↑, 1,   ALAT↝, 1,   AMP↑, 1,   AMPK↓, 1,   AMPK↑, 16,   p‑AMPK↑, 1,   ANXA7↑, 1,   ATP↓, 21,   ATP↑, 2,   CAIX/CA9↑, 1,   citrate↓, 1,   CPT1A↓, 1,   CRM↑, 1,   CYP51/14LDM↓, 1,   ECAR↝, 1,   ECAR∅, 1,   FAM↝, 1,   FASN↓, 4,   FASN↑, 2,   FBPase↑, 1,   GAPDH↓, 1,   glucoNG↓, 1,   glucoNG↑, 1,   glucose↓, 3,   glucose↝, 1,   GlucoseCon↓, 13,   GlutMet↓, 1,   Glycine↓, 1,   Glycolysis↓, 30,   Glycolysis↝, 1,   GSK‐3β↓, 5,   GSK‐3β↑, 5,   p‑GSK‐3β↓, 2,   p‑GSK‐3β↑, 1,   HK2↓, 16,   HMG-CoA↓, 3,   IDH1↓, 1,   KeyT↑, 1,   lactateProd↓, 17,   LDHA↓, 4,   lipoGen↓, 2,   MCT4↓, 1,   NAD↓, 1,   NAD↑, 1,   NADH:NAD↓, 1,   NADPH↓, 2,   NADPH↑, 1,   OAA↑, 1,   PA↑, 1,   PCK1↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 9,   PDKs↓, 3,   p‑PDKs↓, 1,   PFK↓, 3,   PFK1↓, 3,   PFK2?, 1,   PFK2↓, 1,   PKM2↓, 13,   Pyruv↓, 1,   SCD1↓, 1,   SIRT1↓, 5,   SIRT1↑, 6,   SIRT2↓, 1,   SREBP1/SREBF1↓, 1,   TCA↓, 2,   TCA↑, 2,   UGDH↓, 2,   Warburg↓, 13,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 5,   APAF1↑, 2,   Apoptosis?, 1,   Apoptosis↓, 3,   Apoptosis↑, 175,   Apoptosis∅, 1,   mt-Apoptosis↑, 3,   ASK1↑, 1,   BAD↓, 1,   BAD↑, 2,   Bak↑, 6,   BAX↓, 3,   BAX↑, 58,   Bax:Bcl2↑, 13,   Bcl-2↓, 72,   Bcl-2↑, 2,   Bcl-xL↓, 12,   Bcl-xL↑, 1,   BID↑, 2,   cl‑BID↑, 1,   BIM↑, 3,   BNIP3↝, 1,   Casp↓, 1,   Casp↑, 26,   cl‑Casp↑, 2,   Casp1↓, 1,   Casp1↑, 2,   Casp12↝, 1,   Casp2↑, 3,   Casp3↓, 2,   Casp3↑, 89,   cl‑Casp3↑, 19,   cl‑Casp3⇅, 1,   Casp7↑, 11,   cl‑Casp7↑, 3,   Casp8↑, 24,   cl‑Casp8↑, 2,   Casp9↓, 1,   Casp9↑, 44,   p‑Casp9↑, 1,   cl‑Casp9↑, 8,   Cyt‑c↓, 2,   Cyt‑c↑, 44,   Cyt‑c↝, 2,   Diablo↑, 3,   DR5↑, 8,   FADD↑, 1,   Fas↓, 2,   Fas↑, 14,   FasL↓, 1,   FasL↑, 4,   Ferroptosis↓, 1,   Ferroptosis↑, 13,   GSDMD↑, 3,   cl‑GSDME↑, 1,   IAP1↓, 4,   IAP2/BIRC3↓, 2,   ICD↑, 1,   iNOS↓, 8,   iNOS↑, 1,   Mcl-1↓, 11,   Mcl-1↑, 1,   MDM2↓, 3,   MLKL↑, 1,   p‑MLKL↓, 1,   MOMP↑, 4,   Necroptosis↑, 3,   necrosis↑, 5,   NOXA↑, 3,   p38↓, 2,   p38↑, 7,   p‑p38↓, 3,   p‑p38↑, 4,   Paraptosis↑, 1,   pS2/TFF1↓, 1,   PUMA↓, 1,   PUMA↑, 4,   Pyro↑, 5,   RIP3↑, 1,   p‑RIP3↑, 1,   survivin↓, 30,   TRAIL↑, 1,   TRAILR↑, 1,   TumCD↓, 2,   TumCD↑, 28,   TumCD∅, 1,   XIAP↓, 16,   XIAP↑, 1,   YAP/TEAD↓, 1,   YAP/TEAD↑, 1,   YAP/TEAD↝, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 2,   ADCY4↑, 1,   Akt↓, 70,   Akt↑, 4,   p‑Akt↓, 24,   AKT1↓, 2,   AMPKα↑, 2,   BRAF↓, 1,   CK2↓, 1,   cMET↓, 1,   CREB↓, 1,   cSrc↓, 1,   DYRK1B↓, 1,   EF-1α↓, 1,   EGFR↓, 20,   ERK↓, 21,   ERK↑, 5,   p‑ERK↓, 12,   p‑ERK↑, 1,   HER2/EBBR2↓, 5,   HGF/c-Met↓, 1,   IGF-1R↓, 6,   p‑IGF-1R↓, 1,   IGF-2R↑, 2,   IGFR↓, 2,   IKKα↓, 3,   IKKα↑, 1,   IR↓, 1,   p‑IκB↓, 1,   JAK↓, 1,   JAK1↓, 3,   JAK2↓, 5,   JNK↓, 3,   JNK↑, 14,   p‑JNK↓, 1,   p‑JNK↑, 5,   LIFR/CD118↓, 1,   MAPK↓, 15,   MAPK↑, 9,   MAPK↝, 1,   MEK↓, 5,   MKK4↓, 1,   mTOR↓, 37,   mTOR⇅, 1,   mTOR↝, 1,   p‑mTOR↓, 2,   mTORC2↓, 2,   mTORC2↑, 1,   P70S6K↓, 2,   p‑PDGFR-BB↓, 1,   PDGFRA↓, 1,   PDGFRB↓, 1,   PI3K↓, 55,   PI3K↑, 2,   p‑PI3K↓, 2,   PKCδ↓, 2,   PP2A↑, 1,   PTEN↓, 1,   PTEN↑, 22,   p‑PTEN↓, 1,   Raf↓, 1,   c-Raf↓, 1,   RAS↓, 3,   p‑RSK↑, 1,   p‑S6K↓, 2,   Sp1/3/4↓, 1,   Src↓, 3,   STAT↓, 3,   STAT3↓, 44,   p‑STAT3↓, 6,   p‑STAT3↑, 2,   STAT4↑, 1,   STAT5↓, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF2↓, 2,   cJun↓, 2,   cJun↑, 2,   cMyc↓, 10,   DNMT1↓, 1,   DNMT3B↓, 3,   DNMTs↓, 7,   EZH2↓, 2,   FOXM1↓, 2,   FOXO↑, 2,   FOXO1↑, 1,   FOXO3↓, 2,   FOXO3↑, 3,   FOXO3↝, 1,   H3↓, 3,   H3↑, 1,   p‑H3↓, 2,   ac‑H3↓, 1,   ac‑H3↑, 3,   H3K9↓, 1,   H4↑, 2,   ac‑H4↓, 2,   ac‑H4↑, 2,   HATs↓, 1,   HATs↑, 2,   HDAC↓, 22,   HDAC1↓, 4,   HDAC2↓, 4,   HDAC3↓, 1,   HDAC8↓, 3,   HKMT↓, 1,   HMTs↓, 1,   KISS1↑, 1,   miR-106b↓, 2,   miR-124-3p↓, 1,   miR-126↑, 1,   miR-199↓, 1,   miR-19b↓, 2,   miR-200b↑, 1,   miR-203↑, 1,   miR-21↓, 2,   miR-22↑, 2,   miR-29b↑, 1,   miR-30a-5p↑, 1,   miR-34a↑, 1,   miR-375↑, 1,   miR-542↓, 1,   MTA2↓, 1,   Myc↓, 3,   Myc↑, 1,   MYCN↓, 1,   n-MYC↓, 1,   NDRG1↑, 1,   OCT4↓, 4,   other?, 2,   other↓, 12,   other↑, 20,   other↝, 52,   SD↑, 5,   SOX2↓, 5,   SOX4↓, 2,   SUV39H↓, 3,   tumCV↓, 64,   tumCV∅, 1,   UrinaryC↑, 1,   Wmax↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 5,   cl‑CHOP/DDIT3↑, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↑, 1,   p‑eIF2α↓, 1,   p‑eIF2α↑, 1,   ER Stress↓, 1,   ER Stress↑, 19,   GRP78/BiP↓, 3,   GRP78/BiP↑, 1,   p‑Hsc70↑, 1,   HSP27↓, 1,   HSP27↑, 1,   HSP70/HSPA5↓, 3,   HSP70/HSPA5↑, 5,   HSP70/HSPA5⇅, 1,   HSP90↓, 9,   HSP90↑, 1,   HTRA↓, 1,   IRE1↑, 1,   PERK↑, 1,   UBE2L3/UBCH7↑, 1,   UPR↑, 1,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↑, 1,   ATG5↑, 4,   ATG7↑, 1,   Beclin-1/ATG6↑, 8,   Beclin-1/ATG6⇅, 1,   p‑Beclin-1/ATG6↑, 1,   LAMP2↑, 2,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↑, 1,   LC3B-II↑, 1,   LC3I↑, 2,   LC3II↑, 8,   LC3s↑, 1,   lysoMP↑, 1,   MitoP↑, 1,   NEU1↑, 1,   p62↓, 5,   p62↑, 2,   PARK2↑, 1,   SESN2↑, 1,   TumAuto↓, 4,   TumAuto↑, 35,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

8-oxo-dG↓, 1,   8-oxo-dG↑, 1,   APE1/APEX1↓, 1,   ATM?, 1,   ATM↑, 2,   p‑ATM↑, 1,   ATR↑, 1,   BRCA1↓, 1,   BRCA2↓, 1,   DNA-PK↑, 1,   DNAdam↓, 3,   DNAdam↑, 48,   DNArepair↓, 10,   DNArepair↑, 3,   hTERT/TERT↓, 5,   NKX3.1↓, 1,   P53↓, 3,   P53↑, 54,   P53↝, 1,   p‑P53↑, 1,   ac‑P53↑, 1,   p53 Wildtype↓, 1,   PARP↓, 3,   PARP↑, 3,   p‑PARP↑, 1,   cl‑PARP↓, 1,   cl‑PARP↑, 48,   cl‑PARP1↑, 1,   PCNA↓, 12,   SIRT6↓, 1,   SIRT6↑, 2,   Telomerase↓, 11,   TOP1↓, 5,   TOP2↓, 1,   TOP2↑, 2,   TP53↓, 1,   TP53↑, 1,   γH2AX↓, 1,   γH2AX↑, 6,   p‑γH2AX↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1?, 1,   CDK1↓, 4,   CDK1↑, 2,   CDK2↓, 16,   CDK2↑, 1,   CDK4↓, 21,   CDK4↑, 2,   CDK6↓, 5,   CDK6↑, 3,   CDK8↓, 1,   CDKN1C/p57↓, 1,   CDKN1C/p57↑, 1,   cellSen?, 1,   CHK1↓, 2,   CHK1↑, 2,   Chk2↓, 1,   Chk2↑, 3,   Cyc↓, 1,   cycA1/CCNA1↓, 6,   CycB/CCNB1↓, 8,   cycD1/CCND1↓, 35,   cycE/CCNE↓, 7,   E2F4↑, 1,   E2Fs↓, 3,   GADD45A↑, 1,   Ki-67↓, 27,   mitA↑, 3,   P21?, 1,   P21↓, 2,   P21↑, 37,   p27/CDKN1B↓, 3,   p27/CDKN1B↑, 9,   PLK1↓, 3,   p‑pRB↓, 1,   RB1↑, 2,   p‑RB1↓, 4,   TubPol↓, 1,   TumCCA↓, 3,   TumCCA↑, 115,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 2,   CD133↓, 5,   CD24↓, 1,   CD34↓, 1,   cFos↓, 1,   CSCs↓, 23,   CSCsMark↓, 1,   Diff↓, 1,   Diff↑, 5,   EP2↓, 1,   FGF↓, 1,   GH↓, 1,   Gli1↓, 7,   HH↓, 11,   HH↝, 1,   HH∅, 1,   IGF-1?, 1,   IGF-1↓, 11,   IGF-1↑, 1,   IGFBP1↑, 1,   IGFBP3↑, 2,   JAG1↑, 1,   Jun↓, 1,   Ki-67↓, 27,   Let-7↑, 2,   mTORC1↓, 5,   p‑mTORC1↓, 1,   Nanog↓, 4,   Nestin↓, 2,   NOTCH↓, 6,   NOTCH1↓, 7,   NOTCH3↓, 2,   NOTCH3↑, 1,   OGF↑, 2,   OGFr↑, 3,   Piezo1↑, 1,   PTCH1↓, 1,   PTCH2↓, 1,   Shh↓, 2,   Smo↓, 3,   TumCG?, 2,   TumCG↓, 118,   TumCG↑, 2,   TumCG⇅, 2,   TumCG∅, 3,   TumCP↓, 119,   TumCP↑, 3,   TumCP⇅, 2,   WDR72↓, 1,   Wnt↓, 24,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   AntiAg↝, 1,   AP-1↓, 2,   AXL↓, 1,   CA↓, 1,   Ca+2↓, 4,   Ca+2↑, 18,   Ca+2↝, 2,   i-Ca+2↓, 1,   CD11b↑, 1,   Cofilin↓, 1,   COL11A1↓, 1,   COL4A3↓, 1,   E-cadherin↓, 1,   E-cadherin↑, 20,   EMT↓, 29,   EMT↑, 1,   EpCAM↓, 1,   FAK↓, 9,   p‑FAK↓, 2,   p‑FAK↑, 1,   fascin↓, 1,   Fibronectin↓, 1,   GLI3↓, 1,   ITGB1↓, 2,   ITGB4↓, 1,   ITGB6↓, 1,   KRAS↓, 3,   LRP1↑, 1,   MALAT1↓, 2,   MMP1↓, 3,   MMP13↓, 2,   MMP14↓, 2,   MMP2↓, 38,   MMP3↓, 2,   MMP7↓, 2,   MMP9↓, 48,   MMP9↑, 1,   MMPs↓, 23,   MUC4↓, 1,   N-cadherin↓, 13,   Na+↑, 1,   NCAM↓, 1,   PAK1↓, 1,   p‑pax↓, 1,   PDGF↓, 4,   RECK↑, 1,   Rho↓, 2,   ROCK1↓, 1,   Slug↓, 1,   SMAD3↓, 1,   Snail↓, 8,   TGF-β↓, 5,   TGF-β↑, 1,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 5,   TIMP2↑, 5,   TIMP3↑, 1,   TSC1↑, 1,   TSP-1↑, 3,   TumCA↓, 2,   TumCI↓, 48,   TumCI↑, 1,   TumCMig↓, 54,   TumCMig↑, 1,   TumMeta?, 1,   TumMeta↓, 45,   TumMeta↑, 4,   TumPF↓, 1,   Twist↓, 5,   uPA↓, 8,   uPAR↓, 2,   UroPA↓, 1,   Vim↓, 12,   Zeb1↓, 5,   ZEB2↓, 1,   α-tubulin↓, 2,   β-catenin/ZEB1↓, 25,   β-catenin/ZEB1↑, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 67,   angioG↑, 4,   CD31/PECAM-1↓, 2,   CD31/PECAM-1↑, 1,   EGR1↑, 1,   Endoglin↓, 1,   Endoglin↑, 1,   eNOS↑, 1,   HIF-1↓, 6,   Hif1a↓, 39,   Hif1a↑, 2,   Hif1a↝, 1,   Hypoxia↓, 6,   LOX1↓, 1,   NO↓, 1,   NO↑, 4,   PGI2↓, 1,   PHDs↓, 1,   TXA2↓, 1,   TYMP/ECGF1↓, 1,   VCAM-1↓, 3,   VEGF↓, 53,   VEGFR1↓, 2,   VEGFR2/KDR/Flk1↓, 8,   VEGFR2/KDR/Flk1↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 8,   CellMemb↑, 5,   CLDN1↓, 1,   CX43/GJA1↓, 1,   EPR↑, 10,   EPR↝, 1,   GastroP↑, 1,   GLUT1↓, 9,   GLUT1↑, 1,   GLUT2↓, 2,   GLUT3↑, 1,   GLUT4↓, 2,   IBI↑, 1,   K+↑, 1,   MMP?, 1,   MMP↓, 72,   MMP↑, 1,   MMP↝, 1,   MPT↓, 1,   MPT↑, 4,   Na+↑, 1,   NHE1↓, 2,   sonoP↑, 3,   TRPC1↑, 1,   TRPM7↓, 2,   TRPV1↓, 1,   TRPV1↑, 1,   VGCC↓, 1,   VGCC↑, 1,   VGSC↓, 1,   ZO-1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ANXA1↓, 1,   CB2 / CNR2↑, 1,   CCR7↓, 1,   CD14↓, 1,   CD155↓, 1,   CD25+↓, 1,   CD4+↓, 1,   CD4+↑, 2,   CD44↓, 7,   CD47↓, 1,   CD8+↑, 6,   p‑cDC2↓, 1,   COX1↓, 2,   COX1↑, 1,   COX2/PTGS2↓, 45,   COX2/PTGS2↑, 4,   CXCc↓, 1,   CXCL1↓, 1,   CXCL6/GCP-2↓, 1,   CXCR4↓, 6,   Dectin1↝, 1,   DR4↑, 4,   Eos↑, 1,   FOXP3↓, 1,   FOXP3↑, 1,   FoxP3+↓, 1,   Gal-3?, 1,   Gal-3↓, 3,   GM-CSF↓, 1,   HLA-I/II↑, 1,   HMGB1↓, 2,   ICAM-1↓, 2,   IFN-γ↓, 1,   IFN-γ↑, 2,   Igs↓, 1,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 2,   IL1↑, 2,   IL10↓, 5,   IL10↑, 2,   IL12↓, 3,   IL12↑, 1,   IL17↓, 1,   IL18↑, 2,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 16,   IL1β↑, 1,   IL2↓, 2,   IL2↑, 4,   IL22↓, 2,   IL23↓, 1,   IL4↓, 2,   IL4↑, 1,   IL6↓, 32,   IL6↑, 1,   IL8↓, 6,   IL8↑, 1,   Imm↑, 25,   INF-γ↑, 1,   INF-γ↝, 1,   Inflam↓, 38,   IRAK1↓, 1,   LTA/TNF-β↑, 1,   pol-M1↝, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 5,   MIP2↓, 1,   MyD88↑, 1,   NAF1↓, 1,   Neut↓, 1,   Neut↑, 3,   NF-kB↓, 74,   NF-kB↑, 5,   p‑NF-kB↑, 1,   NK cell↑, 16,   NK cell⇅, 1,   NLRP3↓, 2,   NLRP3↑, 2,   p50↓, 2,   p65↓, 4,   p‑p65↓, 1,   PD-1↓, 1,   PD-1↝, 1,   PD-L1↓, 6,   PD-L1↑, 2,   PDT+↓, 1,   PGE2↓, 14,   PSA↓, 20,   RAGE↓, 1,   RANTES↓, 1,   T-Cell↑, 3,   T-Cell↝, 1,   TCF↓, 1,   Th1 response↑, 2,   Th2↑, 1,   TLR4↓, 3,   TLR4↑, 1,   TNF-α↓, 24,   TNF-α↑, 6,   TRADD↑, 1,   Treg lymp↓, 2,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 3,   pH∅, 1,   e-pH↓, 2,   e-pH↑, 4,   i-pH↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 1,   BACE/β-secretase↓, 1,   PSEN1/PS1↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

2/16-OHE1↓, 1,   2/16-OHE1↑, 2,   2/16-OHE1↝, 1,   6IL↑, 1,   ACE/ACE1↓, 1,   AhR↓, 1,   AhR↓, 1,   AhR↑, 1,   AR↓, 13,   AR↝, 3,   CYP19↓, 1,   DHT↓, 1,   ENL↑, 1,   ER-α36↓, 1,   ER(estro)↓, 1,   Estro↝, 1,   EstroRS/ERS↑, 1,   PPARα↓, 2,   PPARγ↑, 4,   PPARγ↝, 1,   RANKL↓, 3,   SHBG↑, 1,   testos↓, 1,   testos∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 38,   BioAv↑, 48,   BioAv⇅, 1,   BioAv↝, 31,   BioEnh?, 1,   BioEnh↑, 3,   ChemoSen?, 1,   ChemoSen↓, 1,   ChemoSen↑, 132,   ChemoSen⇅, 1,   ChemoSen∅, 2,   CompStab↓, 2,   CYP1A1↓, 1,   CYP1A1↑, 1,   CYP1A2↓, 2,   CYP1A2↑, 3,   CYP2A3/CYP2A6↓, 1,   CYP2C9↓, 1,   CYP2E1↑, 1,   CYP3A4↓, 5,   Dose?, 45,   Dose↓, 31,   Dose↑, 69,   Dose⇅, 6,   Dose↝, 626,   Dose∅, 82,   eff?, 2,   eff↓, 48,   eff↑, 170,   eff↝, 32,   eff∅, 15,   GSTA1↑, 1,   GSTM1↑, 1,   GSTZ1↓, 1,   GSTZ1↝, 1,   Half-Life↓, 9,   Half-Life↑, 7,   Half-Life↝, 29,   Half-Life∅, 3,   MDR1↓, 4,   MRP1/ABCC1↓, 2,   P-gp/ABCB1↓, 9,   P-gp/ABCB1↑, 1,   P-gp/ABCB1⇅, 1,   P-gp/ABCB1∅, 1,   P450↓, 4,   RadioS?, 2,   RadioS↓, 1,   RadioS↑, 50,   RadioS↝, 1,   selectivity?, 1,   selectivity↓, 1,   selectivity↑, 122,   Synergy↑, 104,   Synergy↝, 1,   Synergy∅, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 5,   AFP↑, 1,   ALAT↓, 3,   ALAT↑, 1,   ALAT↝, 1,   ALB∅, 1,   ALP↓, 2,   ALP↝, 1,   AR↓, 13,   AR↝, 3,   ascitic↓, 1,   AST↓, 3,   AST↑, 1,   AST↝, 1,   BG↓, 5,   Bil∅, 1,   BloodF↓, 1,   BloodF↑, 6,   BMD↑, 4,   BRAF↓, 1,   BRCA1↓, 1,   BUN↓, 3,   CA125↓, 2,   CEA↓, 1,   CEC↝, 1,   creat↓, 2,   CRP↓, 1,   CRP∅, 1,   CTC↓, 1,   CYFRA21-1↓, 1,   E6↓, 2,   E7↓, 2,   EGFR↓, 20,   EstroRS/ERS↑, 1,   EZH2↓, 2,   Ferritin↓, 1,   FOXM1↓, 2,   HemoG↑, 1,   HER2/EBBR2↓, 5,   hTERT/TERT↓, 5,   IL6↓, 32,   IL6↑, 1,   IRes↓, 1,   KeyT↑, 1,   KRAS↓, 3,   LDH↓, 6,   LDH↑, 2,   Myc↓, 3,   Myc↑, 1,   NLR↓, 1,   NOS2↓, 1,   PC↑, 1,   PD-L1↓, 6,   PD-L1↑, 2,   PSA↓, 20,   PSADT↑, 2,   RAGE↓, 1,   RBC↑, 4,   TP53↓, 1,   TP53↑, 1,   UFR↑, 1,   Urea↓, 1,   Verbal↑, 1,   VitD↑, 1,   WBC↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↓, 1,   AntiCan↑, 57,   AntiCan∅, 1,   antiD↑, 1,   AntiDiabetic↑, 1,   antiNeop↑, 8,   antiNeop∅, 1,   AntiTum↑, 26,   AntiTum∅, 1,   ANXi↓, 1,   APG↓, 2,   cachexia↓, 3,   cardioP↑, 12,   CardioT↑, 1,   chemoP↑, 43,   chemoP∅, 1,   chemoPv↑, 21,   chemoPv⇅, 1,   ChemoSideEff↓, 10,   cognitive↑, 4,   CR↑, 2,   DCR↑, 3,   DCR↝, 1,   fatigue↓, 8,   fatigue↝, 1,   fatigue∅, 1,   hepatoP↑, 11,   LC↑, 2,   mal↓, 1,   memory↑, 4,   Mucositis↓, 6,   Nausea↓, 4,   Nausea∅, 2,   neuroP↑, 11,   NP/CIPN↓, 3,   NP/CIPN↑, 3,   ORR↑, 1,   OS?, 2,   OS↑, 78,   OS↝, 2,   OS∅, 7,   Pain↓, 13,   PFS↓, 1,   PFS↑, 5,   PFS∅, 1,   QoL↑, 32,   QoL↝, 1,   QoL∅, 5,   radioP?, 1,   radioP↑, 23,   Remission↓, 1,   Remission↑, 11,   RenoP↓, 1,   RenoP↑, 6,   Risk↓, 62,   Risk↑, 3,   Risk↝, 2,   Risk∅, 4,   Sleep↑, 2,   stomatitis↓, 1,   Strength↑, 2,   toxicity↓, 59,   toxicity↑, 9,   toxicity↝, 36,   toxicity∅, 6,   TTP↑, 1,   TumNum?, 1,   TumVol?, 1,   TumVol↓, 59,   TumVol⇅, 1,   TumW↓, 22,   TumW⇅, 1,   Vomit↓, 4,   Vomit∅, 2,   Weight↑, 11,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiBio↑, 1,   Bacteria↓, 2,   Dectin1↝, 1,   Diar↓, 1,   Diar⇅, 1,   GutMicro↑, 9,   Inf↓, 2,   Sepsis↓, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 2,   Ingr↑, 1,   Ingr↝, 2,  
Total Targets: 1085

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

3-NT↓, 1,   antiOx?, 1,   antiOx↓, 9,   antiOx↑, 124,   ARE↑, 1,   Bil↓, 2,   Bil↑, 1,   Catalase↑, 42,   DUOX1↓, 1,   Fenton↓, 3,   GCLC↑, 1,   GCLM↑, 1,   GPx↓, 1,   GPx↑, 28,   GPx1↑, 2,   GPx3↑, 1,   GPx4↓, 1,   GPx4↑, 2,   GSH↑, 38,   GSR↑, 7,   GSTs↑, 8,   H2O2↓, 5,   H2O2∅, 2,   HDL↓, 2,   HDL↑, 8,   HDL∅, 1,   HO-1↑, 24,   hyperG↓, 1,   Iron↓, 2,   Iron↑, 1,   lipid-P↓, 35,   MDA↓, 35,   MDA↑, 1,   MPO↓, 8,   NOX↓, 1,   NOX1↓, 1,   NOX2↓, 2,   NOX4↓, 4,   NQO1↑, 6,   NQO1∅, 1,   Nrf1↑, 1,   NRF2↑, 43,   ONOO↓, 1,   PCO↓, 1,   RNS↓, 4,   ROS?, 1,   ROS↓, 160,   ROS↑, 9,   ROS⇅, 4,   ROS∅, 4,   mt-ROS↑, 1,   SAM-e↑, 1,   selenoP↑, 10,   SOD↓, 1,   SOD↑, 59,   SOD1↑, 4,   SOD2↑, 6,   TAC↑, 11,   TBARS↓, 4,   TOS↓, 1,   Trx↑, 1,   Trx1↑, 1,   TrxR1↑, 1,   uricA↓, 4,   VitC↑, 2,   VitE↓, 1,   VitE↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 9,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compII↑, 1,   compIII↑, 1,   compV↑, 1,   EGF↓, 1,   EGF↑, 1,   ETC↓, 1,   Insulin↓, 3,   Insulin↑, 2,   Insulin↝, 1,   mitResp↑, 4,   mtDam↓, 4,   OCR↑, 1,   mt-OCR↑, 1,   OXPHOS↑, 2,   PGC-1α↑, 4,   PINK1↓, 1,   PINK1↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

15-LOX/ALOX15↓, 1,   5LO↓, 2,   ACC↓, 1,   Acetyl-CoA↓, 1,   ACLY↓, 2,   ACLY∅, 1,   AcOH↑, 1,   ACSL4↓, 1,   adiP↑, 1,   e-ADO↑, 1,   ALAT↓, 18,   ALAT↑, 2,   ALAT∅, 1,   AMP↓, 1,   AMPK↑, 11,   ATP↓, 1,   ATP↑, 6,   ATP↝, 1,   Buty↑, 2,   CRM↓, 1,   CRM↑, 2,   DHA↑, 1,   ECAR↑, 1,   FASN↓, 1,   FFA/NEFA↝, 1,   glucose↓, 8,   glucose↑, 1,   glucose↝, 1,   glucose∅, 1,   GlucoseCon↑, 2,   Glycolysis↓, 2,   GSK‐3β↓, 8,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   HK2↓, 2,   HK2↑, 1,   HMG-CoA↓, 3,   IDH1↑, 1,   KeyT↑, 1,   KeyT↝, 1,   lactateProd↓, 1,   LDL↓, 22,   lipidLev↓, 2,   NAD↝, 1,   NADPH↓, 5,   NADPH↑, 5,   NH3↓, 1,   PA↑, 1,   PDK1 / PDPK1↓, 1,   PFK↓, 1,   PGC1A↑, 1,   PKM2↓, 1,   SCFAs↑, 2,   SCFAs∅, 1,   SIRT1↓, 1,   SIRT1↑, 13,   SIRT2↑, 2,   SREBF2↓, 1,   SREBP1/SREBF1↓, 1,   SREBP1/SREBF1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 13,   Apoptosis↑, 1,   ASK1↓, 1,   BAX↓, 8,   BAX↑, 1,   Bax:Bcl2↝, 1,   Bcl-2↓, 2,   Bcl-2↑, 6,   Bcl-xL↑, 1,   BNIP3↓, 1,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 14,   Casp3↑, 1,   cl‑Casp3↓, 1,   Casp8↓, 1,   Casp9↓, 7,   Casp9↑, 1,   Cyt‑c↓, 3,   Fas↓, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 1,   GranB/GZMB↓, 1,   iNOS↓, 19,   p38↓, 5,   p38↑, 1,   p‑p38↓, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 6,   p‑Akt↓, 1,   p‑Akt↑, 1,   AKT1↓, 1,   CREB↑, 1,   p‑CREB↑, 1,   EGFR↓, 1,   ERK↓, 2,   ERK↑, 3,   HCAR2↑, 1,   IGF-1R↓, 1,   IκB?, 1,   JAK↓, 2,   JAK2↓, 1,   JAK2↑, 1,   JNK↓, 4,   p‑JNK↓, 3,   MAPK?, 1,   MAPK↓, 6,   MAPK↑, 3,   MAPK↝, 1,   p‑MAPK↓, 1,   mTOR↓, 3,   p‑mTOR↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 5,   PI3K↑, 6,   PI3K↝, 1,   p‑PI3K↓, 1,   PKCδ↓, 1,   PKCδ↑, 2,   PTEN↓, 2,   PTEN↑, 2,   STAT↓, 1,   STAT3↓, 5,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ac-histone H3↑, 1,   AntiThr↑, 10,   ATF4↓, 2,   cJun↓, 1,   HATs↓, 1,   HDAC↑, 1,   n-MYC↑, 1,   OCT4↓, 1,   other?, 5,   other↓, 9,   other↑, 17,   other↝, 46,   other∅, 2,   SOX18↑, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 4,   eIF2α↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 3,   ER Stress↑, 1,   GRP78/BiP↓, 3,   HSP70/HSPA5↑, 2,   HSP90↓, 1,   HSPs↑, 2,   PERK↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG7↓, 1,   autophagy↓, 1,   CTSZ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3A↑, 1,   LC3B↓, 1,   MitoP↓, 1,   p62↓, 1,   PARK2↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   DNAdam↓, 14,   DNAdam↑, 1,   DNAdam∅, 1,   DNArepair↑, 2,   p16↓, 1,   P53↓, 5,   PCNA↓, 2,   γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK5↓, 2,   E2Fs↑, 1,   GADD45A↑, 1,   Ki-67↓, 3,   Ki-67↑, 1,   P21↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMPs↑, 1,   CD133↑, 1,   Choline↑, 1,   Diff↝, 1,   EP2↑, 1,   Gli1↑, 1,   HMGCR↓, 1,   IGF-1↓, 2,   IGF-1↑, 2,   IGFBP1↑, 1,   IGFBP3↑, 1,   Ki-67↓, 3,   Ki-67↑, 1,   mTORC1↓, 1,   neuroG↑, 1,   Shh↑, 1,   TumCG↓, 2,   TumCP↓, 1,   Wnt↓, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 16,   AntiAg∅, 1,   AP-1↓, 6,   Ca+2?, 1,   Ca+2↓, 6,   Ca+2↑, 3,   Ca+2↝, 3,   Cartilage↑, 6,   COL1↓, 2,   Fibrosis↓, 1,   MMP1↓, 1,   MMP13↓, 1,   MMP2↓, 2,   MMP2↑, 1,   MMP9↓, 7,   Na+↑, 1,   Rho↓, 1,   ROCK1↓, 3,   serineP↓, 1,   p‑SMAD2↓, 1,   p‑SMAD3↑, 1,   TGF-β↓, 1,   TGF-β↑, 2,   TGF-β1↓, 1,   TGF-β1↑, 1,   TIMP1↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumMeta↓, 1,   Tyro3↓, 1,   α-SMA↓, 2,   β-catenin/ZEB1↓, 1,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 2,   E-sel↓, 1,   HIF-1↓, 1,   Hif1a↓, 1,   Hif1a↑, 2,   NO↓, 16,   NO↑, 1,   TXA2↓, 1,   TXA2↑, 1,   VCAM-1↓, 4,   VEGF↓, 1,   VEGF↑, 3,  

Barriers & Transport(tgid=15) ⓘ

AQPs↑, 1,   BBB?, 1,   BBB↑, 34,   BBB↝, 4,   CellMemb↑, 3,   CLDN1↓, 1,   CLDN1↑, 1,   CLDN4↑, 1,   CX43/GJA1↑, 1,   GastroP↑, 4,   GLUT1↑, 1,   GLUT4↑, 1,   GlyFlow↑, 1,   IBI↑, 3,   MMP↓, 2,   MMP↑, 11,   MMP↝, 1,   Na+↑, 1,   OATPs↓, 1,   OCLN↑, 2,   THBD↑, 1,   TJ↓, 1,   TJ↑, 2,   TRPA1↑, 2,   TRPM7↓, 1,   VGCC↓, 1,   VGSC↑, 1,   Vm/CMP↑, 2,   ZO-1↓, 1,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   BALF-Infl↓, 2,   BALF-Lym↓, 1,   CD19↑, 1,   CD25+↑, 1,   CD4+↑, 4,   CD8+↑, 1,   COX1↓, 3,   COX2/PTGS2↓, 34,   CXCL15↓, 1,   CXCR4↓, 1,   Eos↓, 4,   p‑FcεRI↓, 1,   FOXP3↑, 1,   GM-CSF↓, 1,   HCAR2↑, 1,   HMGB1↓, 3,   ICAM-1↓, 5,   IFN-γ↓, 4,   IFN-γ↑, 2,   IgE↓, 3,   IL1↓, 5,   IL10↓, 1,   IL10↑, 7,   IL10∅, 1,   IL12↓, 1,   IL13↓, 2,   IL17↓, 2,   IL17∅, 1,   IL18↓, 2,   IL1α↓, 1,   IL1α∅, 1,   IL1β↓, 31,   IL1β∅, 1,   IL2↓, 2,   IL22↓, 2,   IL4↓, 6,   IL4↑, 4,   IL4∅, 1,   IL5↓, 1,   IL5↑, 1,   IL6↓, 48,   IL6↑, 1,   IL8↓, 5,   IL8∅, 1,   Imm↑, 19,   Inflam↓, 151,   Inflam↑, 1,   LPS↓, 2,   M2 MC↑, 1,   MCP1/CCL2↓, 5,   MCP1/CCL2∅, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   MyD88↓, 1,   NeuroI↓, 7,   Neut↓, 1,   NF-kB↓, 39,   NF-kB↑, 2,   p‑NF-kB↓, 1,   NK cell↑, 3,   NLRP3↓, 8,   NLRP3↑, 2,   p65↓, 1,   p‑p65↓, 1,   PAF↓, 1,   PAF↑, 1,   PGE2↓, 14,   PGE2↑, 1,   PSA↓, 2,   RAGE↓, 3,   RANTES↓, 2,   Th1 response↑, 1,   Th2↓, 1,   TLR2↓, 1,   TLR4↓, 2,   TNF-α↓, 68,   Treg lymp↝, 1,   TRIF↓, 1,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 4,   GGT/CD224↓, 1,   Temp↝, 1,   TREM2↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 1,   5HT↑, 6,   Ach↑, 7,   AChE↓, 27,   AChE↝, 1,   AChE∅, 2,   ADAM10↑, 2,   ADAM10↝, 1,   BChE↓, 4,   BDNF↓, 1,   BDNF↑, 20,   BDNF∅, 1,   BrainVol↑, 2,   BrainVol↝, 1,   BrainVol∅, 1,   CARTPT↑, 1,   ChAT↑, 2,   DA↑, 1,   GABA↓, 2,   GABA↑, 2,   GDNF↑, 1,   MAOA↓, 4,   MAOB↓, 1,   NGF↑, 2,   PSD95↑, 3,   SYP↑, 1,   TrkB↑, 2,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   APOE4↓, 1,   APP↓, 4,   cl‑APP↓, 1,   cl‑APP↑, 1,   Aβ↓, 51,   Aβ42↓, 3,   BACE/β-secretase↓, 11,   PSEN1/PS1↓, 1,   PSEN1/PS1↑, 1,   PSEN2/PS-2↓, 1,   tau↓, 11,   p‑tau↓, 14,   XO↓, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

2/16-OHE1↑, 1,   cortisol↓, 1,   CYP19↓, 1,   DHT↓, 1,   END↑, 1,   ENL↑, 1,   ERβ/ESR2↑, 1,   GLP-1R↑, 1,   GR↑, 1,   Leptin↓, 1,   PPARγ↓, 1,   PPARγ↑, 2,   p‑PPARγ↓, 1,   testos↓, 1,   testos↑, 3,   TSHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv?, 1,   BioAv↓, 49,   BioAv↑, 84,   BioAv⇅, 1,   BioAv↝, 55,   BioAv∅, 2,   BioEnh↑, 6,   CompStab↓, 1,   CompStab↑, 2,   CompStab↝, 1,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 1,   CYP3A4↓, 1,   DDS↑, 2,   Dose?, 25,   Dose↓, 15,   Dose↑, 39,   Dose⇅, 4,   Dose↝, 484,   Dose∅, 10,   eff↓, 9,   eff↑, 70,   eff↝, 10,   eff∅, 1,   GSTA1↓, 1,   GSTA1↑, 2,   Half-Life?, 2,   Half-Life↓, 8,   Half-Life↑, 5,   Half-Life⇅, 1,   Half-Life↝, 37,   Half-Life∅, 4,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 5,   P450↓, 4,   P450↑, 2,   P450↝, 1,   RadioS↑, 1,   selectivity↑, 3,   Synergy↑, 20,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 18,   ALAT↑, 2,   ALAT∅, 1,   ALB↑, 1,   ALP↓, 3,   AST↓, 18,   AST↑, 2,   AST∅, 1,   BG↓, 2,   Bil↓, 2,   Bil↑, 1,   BloodF↑, 12,   BMD↑, 5,   BP?, 1,   BP↓, 21,   BP↝, 1,   BP∅, 1,   p‑BRCA1↑, 1,   BUN?, 1,   Calcium↑, 1,   CCr / CrCl↓, 1,   CCr / CrCl∅, 1,   CK/CK-MB↓, 1,   creat↓, 4,   creat↑, 1,   CRP↓, 11,   EGFR↓, 1,   FEV1↑, 2,   Hcy/homoC↓, 6,   Hcy/homoC↝, 1,   HRV↑, 1,   hs-CRP↓, 3,   IL6↓, 48,   IL6↑, 1,   IRes↓, 1,   IRes↑, 1,   KeyT↑, 1,   KeyT↝, 1,   LDH↓, 5,   LDH↑, 1,   Mag↑, 1,   NLR↓, 1,   NOS2↓, 1,   PEF↑, 1,   PSA↓, 2,   PV↓, 4,   RAGE↓, 3,   rHR↓, 1,   SpO2↑, 1,   TC↓, 3,   TG/TAG↓, 4,   TMAO↑, 5,   TMAO∅, 2,   UFR?, 1,   UFR↑, 2,   UR↓, 2,   Urea↓, 2,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Airway↓, 2,   AirwayM↓, 2,   Anger↓, 1,   AntiAge↑, 16,   AntiAge⇅, 1,   antiAll↑, 21,   AntiArt↑, 5,   AntiCan↑, 16,   antiCG↝, 1,   AntiDiabetic↑, 22,   AntiMyl↑, 1,   antiPs↑, 1,   AntiTum↑, 4,   ANXi↓, 2,   cachexia↓, 1,   cardioP?, 1,   cardioP↓, 1,   cardioP↑, 39,   chemoP↑, 13,   chemoPv↑, 6,   ChemoSideEff↓, 1,   cognitive?, 1,   cognitive↓, 3,   cognitive↑, 112,   cognitive↝, 2,   cognitive∅, 4,   cough?, 1,   diuretic↑, 2,   fatigue↓, 2,   GFR↓, 1,   GFR∅, 1,   hepatoP↓, 3,   hepatoP↑, 47,   IPSS↓, 1,   IPSS↝, 1,   Learn↑, 8,   memory↑, 69,   memory∅, 2,   Mood?, 1,   Mood↑, 6,   motorD↓, 1,   motorD↑, 14,   MusCon↓, 2,   neuroP↑, 108,   neuroP↝, 1,   Obesity↓, 11,   OS↑, 6,   Pain↓, 12,   QoL?, 1,   QoL↑, 13,   radioP↑, 13,   RenoP↑, 14,   Risk↓, 23,   Risk↑, 5,   Risk↝, 1,   RT↓, 2,   Sleep↑, 9,   SoreThr?, 1,   Strength↑, 5,   Stress↓, 7,   Stroke↓, 17,   Tinn↓, 2,   toxicity↓, 79,   toxicity↑, 13,   toxicity⇅, 1,   toxicity↝, 28,   toxicity∅, 24,   UPDRS↓, 1,   Weight↓, 1,   Weight↑, 1,   Weight↝, 1,   Wound Healing↓, 1,   Wound Healing↑, 5,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 11,   AntiFungal↑, 9,   AntiP↓, 1,   AntiP↑, 1,   AntiViral↑, 10,   Bacteria↓, 25,   Diar↓, 3,   GutMicro↑, 28,   GutMicro↝, 1,   GutMicro∅, 1,   Sepsis↓, 4,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 2,   Ingr↝, 8,  
Total Targets: 688

Scientific Paper Hit Count for: Dose, Dosage
44 Magnetic Fields
33 Radiotherapy/Radiation
31 Selenium NanoParticles
27 Hydrogen Gas
23 Curcumin
21 Chemotherapy
19 Silver-NanoParticles
19 Resveratrol
19 Melatonin
18 Lycopene
17 Vitamin C (Ascorbic Acid)
16 EGCG (Epigallocatechin Gallate)
16 Selenium
16 Selenite (Sodium)
15 Ginkgo biloba-EGb 761
15 Magnetic Field Rotating
14 Apigenin (mainly Parsley)
14 Chlorogenic acid
14 Propolis -bee glue
14 Diindolylmethane
12 Carvacrol
12 Sulforaphane (mainly Broccoli)
12 Ginger/6-Shogaol/Gingerol
12 Inositol
12 Licorice
12 Kaempferol
11 Metformin
11 buckwheat sprouts
11 Choline
11 Ellagic acid
11 Folic Acid, Vit B9
11 Flaxseed/Linseed
11 SDG/lignans
11 Hyperthermia
10 isoquercitrin
10 Hydroxycinnamic-acid
10 Lemongrass Extract/Citral
10 Lactoferrin/Talactoferrin
9 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
9 Baicalein
9 Dichloroacetate
9 Indole-3-carbinol
9 Exercise
9 Ginkgo biloba
9 itraconazole
9 Marjoram (Origanum majorana)
8 Rutin
8 Auranofin
8 Cisplatin
8 Citric Acid
8 doxorubicin
8 Ferulic acid
8 Fenbendazole
8 Fisetin
8 Fucoidan
8 Ginkgetin
8 HydroxyTyrosol
8 Silymarin (Milk Thistle) silibinin
8 mebendazole
7 3-bromopyruvate
7 α-Bisabolol / Chamomile oil
7 Quercetin
7 Mung Bean Sprouts
7 Capsaicin
7 Centella asiatica / Gotu kola → asiaticoside
7 chitosan
7 Echinacea
7 Electrical Pulses
7 Formononetin
7 Vitamin D3
7 Gamma-aminobutyric acid
7 Genistein (soy isoflavone)
7 Hibiscus sabdariffa
7 Lutein
7 Matrine
7 Thymoquinone
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Aspirin
6 Astaxanthin
6 Vitexin
6 Caffeic acid
6 immunotherapy
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Dandelion Root
6 Eugenol
6 Ivermectin
6 Flaxseed Oil
6 Lemon Balm/Melissa officinalis
6 Honokiol
6 phytic acid, Inositol hexakisphosphate
6 iodine
6 Inulin Prebiotic
6 Luteolin
6 Rosmarinic acid
6 Methylsulfonylmethane
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Cynara scolymus/Globe Artichoke/Artichoke Extract
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Ashwagandha(Withaferin A)
5 Paclitaxel/Taxol
5 Boron
5 isoorientin
5 Isovitexin
5 Chocolate
5 Spermidine
5 Oxygen, Hyperbaric
5 diet FMD Fasting Mimicking Diet
5 Vitamin B12
5 Gossypol/AT-101
5 Grapeseed extract
5 capecitabine
5 Isoliquiritigenin
5 isoflavones
5 Licochalcone A
5 MCT, metronomic chemo
5 Modified Citrus Pectin
5 Magnesium
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 EMF
5 VitK3,menadione
4 cetuximab
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Celastrol
4 Chrysin
4 Chyawanprash
4 Cichoric acid / Chicoric acid
4 Coenzyme Q10
4 HydroxyCitric Acid
4 Garcinol
4 Crocetin
4 Diclofenac
4 Docosahexaenoic Acid
4 eicosapentaenoic acid
4 Shilajit/Fulvic Acid
4 Gallic acid
4 probiotics
4 Methylene blue
4 Magnolol
4 Mistletoe/Viscum album Extracts
4 Propyl gallate
3 Photodynamic Therapy
3 Astragalus
3 Bevacizumab (brand Avastin)
3 Fennel Oil/Foeniculum vulgare
3 Angelica archangelica / Garden Angelica
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Beta-Caryophyllene
3 Bromelain
3 borneol
3 Sorafenib (brand name Nexavar)
3 Cat’s Claw
3 chaetocin
3 Calorie Restriction Mimetics
3 Dasatinib/Phyrago
3 Disulfiram
3 Eurycomanone
3 Silicic Acid
3 Gambogic Acid
3 Huperzine A/Huperzia serrata
3 Isobavachalcone
3 Lapatinib
3 low dose naltrexone
3 Linalool
3 Zeaxanthin
3 Morin
3 Oleuropein
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Turmerones
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 1,8-Cineole
2 Glucose
2 almonertinib
2 DTS(dibenzyl trisulphide) from Anamu
2 Anti-oxidants
2 Aromatherapy
2 Ascorbyl Palmitate
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Bortezomib
2 Lecithin
2 Calcium
2 Celecoxib
2 Cynaropicrin
2 diet Plant based
2 diet Short Term Fasting
2 tamoxifen
2 D-limonene
2 Docetaxel
2 Zinc
2 Emodin
2 5-fluorouracil
2 Evodiamine
2 Vitamin B6,pyridoxine
2 Flickering Light Stimulation
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Germanium inorganic
2 Geraniol
2 Ginkgolide B
2 Gold NanoParticles
2 Germacranolide sesquiterpene lactone
2 Helleborus niger extracts – Christmas Rose
2 Recombinant Methioninase
2 Juglone
2 Potassium
2 L-ornithine
2 Lactobacillus
2 MCT oil
2 nivolumab
2 magnetic nanoparticles
2 Iron
2 Niclosamide (Niclocide)
2 Terpinen-4-ol / Tea Tree Oil
2 Bifidobacterium
2 Phosphatidylserine
2 Rauwolfia serpentina/Indian Snakeroot
2 Ursolic acid
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Annona atemoya Leaf Extract
1 Anethole/trans-Anethole
1 Acer okamotoanum
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 brusatol
1 Bruteridin(bergamot juice)
1 Black Seed Oil/Nigella sativa
1 urea
1 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
1 Catechins
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Chlorophyllin
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 CUSP9
1 Cysteamine
1 diet Ketogenic
1 Ormeloxifene (Centchroman)
1 Dipyridamole
1 Protocatechuic acid
1 Estragole
1 Aluminum
1 ferumoxytol
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Trastuzumab
1 Arsenic trioxide
1 Vitamin A, Retinoic Acid
1 Salvia officinalis
1 Bifidobacterium animalis subsp. lactis GCL2505
1 Glabrescione B
1 carboplatin
1 Graviola
1 hydrogen sulfide
1 High-Ozonide Oil
1 Hormone replacement therapy
1 Hyperoside
1 Extracorporeal Shock Wave Therapy
1 Anthocyanins
1 Gemcitabine (Gemzar)
1 lambertianic acid
1 Lapachol
1 Lasiodin
1 Methyl Jasmonate
1 methylseleninic acid
1 Sulodexide
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 ipilimumab
1 Aidi injection
1 Phenolic Acids
1 Polyphenols
1 alpha Linolenic acid
1 Pterostilbene
1 Pumpkin Seed Oil / Cucurbita pepo
1 Tamsulosin
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 Sinapic acid
1 salinomycin
1 α-Santalol/Sandalwood oil
1 Sulfasalazine
1 irinotecan
1 Taurine
1 triptolide
1 Triphala
1 Thymol-Thymus vulgaris
1 Vanillic Acid
1 Transarterial Chemoembolization
1 Valerian / Valeriana officinalis
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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