BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
Scientific Papers found: Click to Expand⟱
3261- Lyco,    Lycopene and Vascular Health
- Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiAg↑, *cardioP↑, *SOD↑, *Catalase↑, *ROS↓, *mtDam↓, *cardioP↑, *NF-kB↓, *NO↓, *COX2/PTGS2↓, *LDL↓, *Synergy↑, *ER Stress↓, *BioAv↑, *Synergy↑, *MMPs↓, *COX2/PTGS2↓, *RAGE↓,
3277- Lyco,    Recent trends and advances in the epidemiology, synergism, and delivery system of lycopene as an anti-cancer agent
- Review, Var, NA
antiOx↑, TumCP↓, Apoptosis↑, TumMeta↑, ChemoSen↑, BioAv↓, Dose↝, BioAv↓, BioAv↑, SOD↑, Catalase↑, GPx↑, IL2↑, IL4↑, IL1↑, TNF-α↑, GSH↑, GPx↑, GSTA1↑, GSR↑, PPARγ↑, Casp3↑, NF-kB↓, COX2/PTGS2↓, Bcl-2↑, BAX↓, P53↓, CHK1↓, Chk2↓, γH2AX↓, DNAdam↓, ROS↓, P21↑, PCNA↓, β-catenin/ZEB1↓, PGE2↓, ERK↓, cMyc↓, cycE/CCNE↓, JAK1↓, STAT3↓, SIRT1↑, cl‑PARP↑, cycD1/CCND1↓, TNF-α↓, IL6↓, p65↓, MMP2↓, MMP9↓, Wnt↓,
1710- Lyco,    Lycopene: A Natural Arsenal in the War against Oxidative Stress and Cardiovascular Diseases
- Review, CardioV, NA
antiOx↓, ROS↓, BP↓, LDL↓, *toxicity∅, eff↑, ROS↑, *Half-Life↑, *BioAv↓, *BioAv↑, *antiOx↑,
8421- Lyco,    Lycopene: Sojourn from kitchen to an effective therapy in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *antiOx↑, *Inflam↓, *AntiMyl↑, *ROS↓, *MMP↑, *NGF↑, *BDNF↑, *VEGF↑, *Aβ42↓, *PI3K↑, *Akt↑, *NRF2↑, *lipid-P↓, *GSH↑, *Catalase↑, *SOD↑, *cognitive↑, *Learn↑, *memory↑, *APP↓, *BACE/β-secretase↓, *ADAM10↑, *NF-kB↓, *AChE↓, *MAOA↓, *BioAv↝,
8418- Lyco,  docx,    A phase I study of docetaxel plus synthetic lycopene in metastatic prostate cancer patients
- Trial, Pca, NA
Dose↝, BioEnh↑, angioG↓, IGF-1↓, ChemoSen↑, BioAv↑, CEC↝,
8414- Lyco,    Exploring the Therapeutic Potential of Lycopene: Mechanisms, Biological Activities, and Health Benefits
- Review, Var, NA - Review, AD, NA
*ROS↓, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiArt↑, *Obesity↓, *Wound Healing↑, *BioAv↑, *GSTs↑, *Trx1↑, *SOD↑, *Catalase↑, *ALAT↓, *LDH↓, *AST↓, *MDA↓, *cognitive↑, *memory↑, *NeuroI↓, *Aβ↓, *LRP1↑, *RAGE↓, *NRF2↑, *HO-1↑, tumCV?, Bax:Bcl2↑, DNAdam↑, Apoptosis↑, β-catenin/ZEB1↓, cMyc↓, cycD1/CCND1↓, ROS↓, TumCCA↑, Akt↓, *Synergy↑, *MDA↓, *NF-kB↓, *TGF-β↓, *Casp3↓, *Catalase↑, *GSH↑, *Bcl-2↑, *IL10↑, *MUC1↑, *IBI↑, *RenoP↑, *ChemoSen↑, *Synergy↑, *Synergy↑, *BMD↑,
8408- Lyco,    Enhanced bioavailability of lycopene when consumed as cis-isomers from tangerine compared to red tomato juice, a randomized, cross-over clinical trial
- Trial, Nor, NA
*BioAv↑, *Dose↝,
4782- Lyco,    New Insights into Molecular Mechanism behind Anti-Cancer Activities of Lycopene
- Review, Var, NA
AntiCan↑, TumCP↓, TumCMig↓, TumCI↓, TumCA↓, ROS↓, MMP2↓, MMP7↓, MMP9↓, VEGF↓, E-cadherin↑, TIMP1↑, TIMP2↑, BioAv↝, *IL12↓, *TNF-α↓, *IL1↓, *IL1β↓, *IL6↓, COX2/PTGS2↓, iNOS↓, *radioP↑, NF-kB↓, survivin↓, Casp3↑, Bax:Bcl2↑,
4788- Lyco,    Lycopene as a potential anticancer agent: Current evidence on synergism, drug delivery systems and epidemiology (Review)
- Review, Var, NA
AntiCan↑, ChemoSen↑, chemoP↑, Dose↝, BioAv↑, BioAv↑, BioAv↓, cardioP↑, AntiDiabetic↑, hepatoP↑, neuroP↑, MAPK↓, MMP2↓, MMP9↓, TIMP1↑, TIMP2↑,
4801- Lyco,    Lycopene in the Prevention of Cardiovascular Diseases
- Review, CardioV, NA
*BioAv↝, *cardioP↑, *BioAv↑, *BioAv↑, *antiOx↑, *ROS↓, *ARE↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *COX2/PTGS2↓, *Inflam↓, *IL1β↓, *IL6↓, *IL8↑, *TNF-α↓, *NF-kB↓, *BP↓,
4796- Lyco,    The Anti-proliferation Effects of Lycopene on Breast Cancer Cells
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10
TumCG↓, selectivity↑, *BioAv↑, *antiOx↑, *ROS↓, Risk↓, *cardioP↑,
4792- Lyco,    A Comprehensive Review on the Molecular Mechanism of Lycopene in Cancer Therapy
- Review, Var, NA
*AntiCan↑, *antiOx↑, Inflam↓, Wnt↓, β-catenin/ZEB1↓, *ROS↓, BioAv↑, ROS↓, Risk↓, PGE2↓, COX2/PTGS2↓, p‑ERK↓, P21↑, MMP7↓, MMP9↓, ChemoSen↑, Synergy↑,
8727- M-Blu,    High absolute bioavailability of methylene blue given as an aqueous oral formulation
- Trial, Nor, NA
*Dose?, *BioAv↑,
8733- M-Blu,    Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation
- Review, AD, NA - Review, Stroke, NA
*ETC↑, *ROS↓, *Inflam↓, *memfluid↑, *BloodF↑, *BBB↑, *OCR↑, *ATP↑, *BioAv↑, *Aβ↓, *compIV↑, *Stroke↓, *compI↑, *compII↑, *compIII↑, *GlucoseCon↑, *neuroG↑,
2542- M-Blu,    In Vitro Methylene Blue and Carboplatin Combination Triggers Ovarian Cancer Cells Death
- in-vitro, Ovarian, OV1369 - in-vitro, Ovarian, OV1946 - in-vitro, Nor, ARPE-19
BioAv↝, TumCP↓, GlutaM↓, Warburg↓, OCR↑, Glycolysis↓, ATP↓, BioAv↝, ROS↑,
5252- MAG,    Insights on the Multifunctional Activities of Magnolol
- Review, Var, NA
BioAv↓, *Inflam↓, *Bacteria↓, *antiOx↑, *neuroP↑, *cardioP↑, CYP1A1↓, *PPARγ↑, *NF-kB↓, *COX2/PTGS2↓, *iNOS↓, *ROS↓, Apoptosis↑, TumCCA↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, P21↑, TumCG↓, TumCMig↓, TumCI↓, Ki-67↓, PCNA↓, MMP2↓, MMP9↓, MMP7↓, DNAdam↑, MMP↓, TumCP↓, selectivity↑, PI3K↓, Akt↓, H2O2↓, Hif1a↓, *BDNF↑, *NRF2↑, *AChE↑,
8495- MAG,    Pharmacokinetics, bioavailability, and tissue distribution of magnolol following single and repeated dosing of magnolol to rats
- in-vivo, Nor, NA
*Dose↝, *other?, *BioAv↝,
8513- MAG,    Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I
- vitro+vivo, Oral, SCC4 - in-vitro, Tong, SCC9 - in-vitro, SCC, CAL27
TumCG↓, TumMeta↓, *toxicity↓, Ingr?, chemoPv↑, compI↓, mitResp↓, ETC↓, AMPK↑, STAT3↓, ox-PrxI↑, Dose↝, Ki-67↓, STAT3↓, P70S6K↓, HK2↓, survivin↓, BioAv↝, Half-Life↝, ROS↑,
8512- MAG,    Enhanced Oral Bioavailability of the Pharmacologically Active Lignin Magnolol via Zr-Based Metal Organic Framework Impregnation
- in-vivo, Nor, NA
*other↝, *toxicity↓, *Half-Life↑, *BioAv↑,
8510- MAG,    Pharmacokinetic and Metabolic Profiling of Key Active Components of Dietary Supplement Magnolia officinalis Extract for Prevention against Oral Carcinoma
- in-vitro, Oral, CAL27 - in-vitro, Tong, SCC9 - in-vitro, SCC, SCC4
Ingr?, BioAv↓, other↝, BioAv↓, Half-Life↓,
8504- MAG,    Magnolol nanoparticles combat MRSA by disrupting TCA cycle and arginine metabolism to induce oxidative stress
- in-vitro, Var, NA
*BioAv↓, *CompStab↑, *Bacteria↓, *eff↑, TCA↝, ROS↑, SOD↓,
4514- MAG,    Magnolol and its semi-synthetic derivatives: a comprehensive review of anti-cancer mechanisms, pharmacokinetics, and future therapeutic potential
- Review, Var, NA
AntiCan↑, TumCP↓, TumCCA↑, TumMeta↓, angioG↓, NF-kB↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, BioAv↓, *antiOx↑, *Inflam↓, *AntiAg↑, ChemoSen↑, cycD1/CCND1↓, CycB/CCNB1↓, cycE/CCNE↓, CDK2↓, CDK4↓, p27/CDKN1B↑, P21↑, P53↑, PTEN↓, XIAP↓, Mcl-1↓, Casp3↑, Casp9↑, MMP9↑,
4528- MAG,    Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update
- Review, Nor, NA
*Inflam↑, *cardioP↑, *angioG↓, *antiOx↑, *neuroP↑, *Bacteria↓, AntiTum↑, TumCG↓, TumCMig↓, TumCI↓, Apoptosis↑, E-cadherin↑, NF-kB↓, TumCCA↑, cycD1/CCND1↓, PCNA↓, Ki-67↓, MMP2↓, MMP7↓, MMP9↓, TumCG↓, Casp3↑, NF-kB↓, Akt↓, mTOR↓, LDH↓, Ca+2↑, Synergy↑, *toxicity↓, *BioAv↝, *PGE2↓, *TLR2↓, *TLR4↓, *MAPK↓, *PPARγ↓,
4525- MAG,  HNK,    Magnolol and Honokiol: Two Natural Compounds with Similar Chemical Structure but Different Physicochemical and Stability Properties
- Study, Nor, NA
*BioAv↝, *CompStab↑,
4519- MAG,    Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer
- Review, Var, NA
*antiOx↑, *Inflam↓, *Bacteria↓, *AntiAg↑, *BBB↑, *BioAv↓, BAD↑, Casp3↑, Casp6↑, Casp9↑, JNK↑, Bcl-xL↓, PTEN↑, Akt↓, NF-kB↓, MMP7↓, MMP9↓, uPA↓, Hif1a↓, VEGF↓, FOXO3↓, Ca+2↑, TumCCA↑, ROS↑, Cyt‑c↑,
8538- Matr,    Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling
- in-vitro, BC, MDA-MB-231 - ex-vivo, BC, MDA-MB-231
TumCP↓, Synergy↑, Apoptosis?, Bax:Bcl2↑, TumCI↓, MMP9↓, MMP2↓, Akt↓, NF-kB↓, VEGFR1↓, BioAv↝,
8526- Matr,    A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine
- Review, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *AntiViral↑, *Bacteria↓, *antiAll↑, *Analgesic↑, *hepatoP↑, *cardioP↑, *neuroP↑, *toxicity↝, p38↓, IL6↓, JAK2↓, STAT3↓, Casp↑, PI3K↓, Akt↓, mTOR↓, Beclin-1/ATG6↑, PCNA↓, Bcl-2↓, XIAP↑, VEGF↓, NF-kB↓, MMP2↓, MMP9↓, P-gp/ABCB1↓, survivin↓, OCT4↓, SOX2↓, p62↓, *TNF-α↓, *IL6↓, *HMGB1↓, *AntiArt↑, *NF-kB↓, *IL6↓, *IL8↓, *IL1β↓, *IL17↓, *TNF-α↓, *ROS↓, *NRF2?, *AST↓, *ALAT↓, *TGF-β↓, *α-SMA↓, *JAK2↑, *STAT3↑, *BioAv↝, *Half-Life↝, ChemoSen↑, ATP↓, ROS↑,
8555- Matr,    Matrine Exerts Pharmacological Effects Through Multiple Signaling Pathways: A Comprehensive Review
- Review, Var, NA
*AntiTum↑, *Inflam↓, *Analgesic↑, *AntiViral↑, *Imm↑, *PI3K↑, *Akt↑, *mTOR↑, TumAuto↑, PI3K↓, Akt↓, mTOR↓, Beclin-1/ATG6↑, E-cadherin↑, Vim↓, MMP2↓, MMP9↓, Snail↓, Slug↓, PTEN↑, TumCP↓, TumCMig↓, TumCI↓, ChemoSen↑, ROS↑, uPA↓, p‑ERK↓, cachexia↓, antiD↑, GSK‐3β↓, LC3B-II↑, p62↓, Apoptosis↑, Casp3↑, Casp8↑, Casp9↑, FOXO1↑, FOXO3↑, FOXO4↑, PARP↑, BIM↑, Bcl-2↓, survivin↓, miR-21↓, *HOTAIR↑, *p‑Akt↑, *p‑STAT3↑, *STAT3↑, *ROS↓, Wnt↓, β-catenin/ZEB1↓, NOTCH1↓, JAG1↓, HES1↓, BioAv↝, toxicity↝,
8551- Matr,    Research Progress of Natural Matrine Compounds and Synthetic Matrine Derivatives
- Review, Nor, NA
*BioAv↓, *toxicity↑, *AntiTum↑, *AntiViral↑, *Inflam↓, *hepatoP↑, *Analgesic↑, *Half-Life↓, *toxicity↓,
8645- MBZ,    HPMA Copolymer Mebendazole Conjugate Allows Systemic Administration and Possesses Antitumour Activity In Vivo
- vitro+vivo, Colon, CT26
BioAv↓, BioAv↑, Half-Life↑, EPR↑, AntiTum↑,
8648- MBZ,    Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature
- Review, Var, NA
angioG↓, MMPs↓, MDR1↓, TubPol↓, RadioS?, ChemoSen?, TumCG↓, TumMeta?, OS↑, BioAv↓, BioAv↑, BBB↑, mitA↑, HH↓, Shh↓, Synergy↑, Gli1↓, PTCH2↓, XIAP↓, cl‑PARP↑, Casp3↑, BRAF↓, MEK↓, SYN1↑, Cyt‑c↑, TumVol↓, VEGFR2/KDR/Flk1↓, VEGF↓, VCAM-1↓, DYRK1B↓, QoL↑, Dose↝,
8646- MBZ,    Extensive improvement of oral bioavailability of mebendazole, a brick dust, by polymer-containing SNEDDS preparation: Disruption of high crystallinity by utilizing its counter ion
- in-vivo, Var, NA
BioAv↓, other↝, BioAv↑, BioAv↑,
8812- MCP,    Investigation of Antitumor Activity of Modified Citrus Pectin: Oral and Intravenous Administration Assessed via Molecular Imaging
- vitro+vivo, Ovarian, SKOV3 - in-vitro, GC, MKN-28 - in-vitro, BC, 4T1
BioAv↓, TumCG↓, eff↓,
8620- MCT,    Medium-Chain Triglycerides: Scientific and Regulatory Perspectives from Germany and Japan with a US Context—A Concise Review
- Review, Nor, NA
*BioAv↑, *toxicity↓, *Obesity↓, *Akt↑, *mTOR↑, *Synergy↑, *cognitive↑, *Obesity↓,
6541- MeSal,    Toxicology Answer: Oil of Wintergreen
- Review, Nor, NA
*Inflam↓, *Pain↓, *BioAv↝, *BloodF↑, *toxicity↑,
6537- MeSal,    The ancient drug salicylate directly activates AMP-activated protein kinase
- Review, Nor, NA
*BioAv↝, *AMPK↑, *Half-Life↝,
8707- MET,    Metformin in therapeutic applications in human diseases: its mechanism of action and clinical study
- Review, Var, NA - Review, AD, NA
*BioAv↝, *cardioP↑, *Obesity↓, *neuroP↑, *toxicity↝, *Dose↝, *GutMicro↑, *AMPK↑, *glucose↓, *NLRP3↑, *Inflam↓, *Stroke↓, *Cartilage↑, FOXP3↑, TumAuto↑, mTOR↓, PD-L1↓, RadioS↑, ChemoSen↑, ROS↓, OXPHOS↓, compI↓, Glycolysis↝, TumCP↓, *BioAv↝, *AntiAge↑, *SIRT1↑, *cognitive↑, *Risk↓, Ki-67↓, Synergy↝, PFS∅, OS∅,
8708- MET,    Tumour, whole-blood, plasma and tissue concentrations of metformin in lung cancer patients
- Human, Lung, NA
BioAv↓, BioAv↑, Half-Life↝, Dose↓, compI↓,
5795- MET,    Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes
- Review, AD, NA - Review, Park, NA - Review, Diabetic, NA
*AntiDiabetic↑, *AMPK↑, *glyC↓, *ROS↓, *cardioP↑, *neuroP↑, *Half-Life↝, *toxicity↝, *BioAv↑, *glucose↓, *AGEs↓, AntiCan↑, Risk↓, TumCP↓, Apoptosis↑, TumCCA↑, cycD1/CCND1↓, pRB↓, p27/CDKN1B↓, mTOR↓, Casp↑, ROS↑, MMP↓, ChemoSen↑, *hepatoP↑, *CRM↑, *Insulin↓,
2250- MF,  MNPs,    Confronting stem cells with surface-modified magnetic nanoparticles and low-frequency pulsed electromagnetic field
- Review, Var, NA
Ca+2↑, Dose↝, BioAv↓,
3468- MF,    An integrative review of pulsed electromagnetic field therapy (PEMF) and wound healing
- Review, Nor, NA
*other↑, *necrosis↓, *IL6↑, *TGF-β↑, *iNOS↑, *MMP2↑, *MCP1/CCL2↑, *HO-1↑, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *BioAv↑, eff⇅, DNAdam↑, Apoptosis↑, ROS↑, TumCP↓, *ROS↓, *FGF↑,
8462- Mg,    Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study
- Trial, Nor, NA
*BioAv↑,
782- Mg,    Oral magnesium supplements for cancer treatment‐induced hypomagnesemia: Results from a pilot randomized trial
- Trial, Var, NA
*BioAv↑,
1782- MLT,    Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities
- Review, Var, NA
AntiCan↑, Apoptosis↑, TumCP↓, TumCG↑, TumMeta↑, ChemoSideEff↓, radioP↑, ChemoSen↑, *ROS↓, *SOD↑, *GSH↑, *GPx↑, *Catalase↑, Dose∅, VEGF↓, Synergy↑, Hif1a↓, GLUT1↑, GLUT3↑, CAIX/CA9↑, P21↑, p27/CDKN1B↑, PTEN↑, Warburg↓, PI3K↓, Akt↓, NF-kB↓, cycD1/CCND1↓, CDK4↓, CycB/CCNB1↓, CDK4↓, MAPK↑, IGF-1R↓, STAT3↓, MMP9↓, MMP2↓, MMP13↓, E-cadherin↑, Vim↓, RANKL↓, JNK↑, Bcl-2↓, P53↑, Casp3↑, Casp9↑, BAX↑, DNArepair↑, COX2/PTGS2↓, IL6↓, IL8↓, NO↓, T-Cell↑, NK cell↑, Treg lymp↓, FOXP3↓, CD4+↑, TNF-α↑, Th1 response↑, BioAv↝, RadioS↑, OS↑,
8673- MLT,    Therapeutic Potential of Melatonin in Gastrointestinal Cancers: Molecular Mechanisms, Preclinical Evidence and Clinical Implications
- Review, GC, NA
ChemoSen↑, TumVol↓, β-catenin/ZEB1↓, Risk↓, radioP↑, Mucositis↓, Dose↝, toxicity↓, BioAv↓, *antiOx↑, *SOD↑, *GPx↑, *Catalase↑, *NRF2↑, Apoptosis↑, Estro↝, Telomerase↓, *ROS↓, angioG↓, Imm↑, TumCCA↑, Glycolysis↓, OXPHOS↑, mTORC1↓, VEGF↓, Hif1a↓, ROS↓, TumAuto↓, HSP70/HSPA5↓, PI3K↓, Akt↓, mTOR↓, BAX↑, Casp↑, Cyt‑c↑, tumCV↓, TumCMig↓, TumCI↓, TumVol↓, TumW↓, P21↑, P53↑, Synergy↑, ER Stress↑, Synergy↑, RadioS↑, eff↑, eff↑, fatigue↓, Sleep↑,
8683- MLT,    Intra-tumor ROS amplification by melatonin interferes in the apoptosis-autophagy-inflammation-EMT collusion in the breast tumor microenvironment
- in-vivo, BC, NA
ROS↑, SIRT1↑, IL6↓, STAT3↓, NF-kB↓, PI3K↓, Akt↓, mTOR↓, TumCP↓, tumCV↓, JNK↑, P53↑, Bax:Bcl2↑, cl‑Casp3↑, Apoptosis↑, eff∅, TumAuto↑, EMT↓, Half-Life↓, CompStab↓, BioAv↓, Dose↝, TumW↓, TumVol↓, Ki-67↓, PTEN↑,
656- MNPs,  MF,    Effects of combined delivery of extremely low frequency electromagnetic field and magnetic Fe3O4 nanoparticles on hepatic cell lines
- in-vitro, HCC, HepG2 - in-vitro, Nor, HL7702
BioAv↑, Apoptosis↑, *toxicity↓,
8901- MOR,    Preparation, characterization, and in vivo evaluation of a self-nanoemulsifying drug delivery system (SNEDDS) loaded with morin-phospholipid complex
- in-vivo, Nor, NA
*BioAv↑, *Dose↝, *eff↑, *BioAv↑, *Half-Life↑, *BioAv↑,
8902- MOR,    Enhanced oral bioavailability of morin administered in mixed micelle formulation with PluronicF127 and Tween80 in rats
- vitro+vivo, Nor, NA
*Dose↝, *BioAv↑, *EPR↑, *other↑, *P-gp/ABCB1↓, *other↑,
8903- MOR,  QC,    Profound difference in pharmacokinetics between morin and its isomer quercetin in rats
- in-vivo, Nor, NA
*BioAv↝, *BioAv↝, *BioAv↝, *BioAv↝,

Showing Research Papers: 601 to 650 of 860
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 860

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 5,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 17,   ARE↓, 1,   Catalase↓, 7,   Catalase↑, 5,   Fenton↑, 4,   frataxin↑, 1,   GPx↓, 3,   GPx↑, 5,   GPx4↓, 11,   GPx4↑, 1,   GSH↓, 34,   GSH↑, 7,   GSH/GSSG↓, 1,   GSR↓, 2,   GSR↑, 1,   ox-GSSG↑, 1,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 4,   e-H2O2↓, 1,   i-H2O2∅, 1,   HO-1↓, 6,   HO-1↑, 10,   HO-2↓, 1,   Iron↑, 5,   Iron↝, 1,   i-Iron↑, 1,   c-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 8,   lipid-P↑, 15,   MDA↓, 3,   MDA↑, 5,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NOX4↑, 1,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 16,   NRF2↑, 23,   Prx↓, 1,   Prx4↑, 1,   Prx6↑, 1,   ox-PrxI↑, 1,   PrxII↓, 1,   PYCR1↓, 1,   ROS?, 1,   ROS↓, 28,   ROS↑, 236,   ROS⇅, 9,   ROS↝, 3,   i-ROS↓, 1,   i-ROS↑, 2,   mt-ROS↑, 1,   SOD↓, 9,   SOD↑, 8,   SOD1↓, 2,   SOD2↓, 4,   SOD2↑, 1,   Thiols↓, 2,   Trx↓, 2,   Trx1↑, 1,   TrxR↓, 8,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 5,   Tf↓, 1,   Tf↑, 1,   TfR1/CD71↑, 2,   Zn2+↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 2,   BCR-ABL↓, 1,   CDC2↓, 4,   CDC25↓, 5,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   compV↓, 1,   EGF↓, 2,   ETC↓, 3,   ETC↑, 1,   MFN2↑, 1,   mitResp↓, 2,   Mortalin↓, 1,   mtDam↓, 1,   mtDam↑, 16,   OCR↓, 2,   OCR↑, 3,   OXPHOS↓, 5,   OXPHOS↑, 3,   mt-OXPHOS↓, 2,   PDH↑, 2,   PGC-1α↑, 1,   PINK1↑, 1,   SDH↑, 1,   SIRT3↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 1,   5LO↓, 5,   ACLY↓, 2,   ACSL4↑, 1,   ALAT↓, 6,   ALAT↑, 1,   ALDOA↓, 1,   AMPK↑, 19,   AMPK↝, 1,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 18,   ATP↑, 1,   mt-ATP↓, 1,   CAIX/CA9↓, 1,   CAIX/CA9↑, 1,   CRM↝, 1,   ECAR↓, 3,   ECAR↝, 1,   ENO1↓, 2,   FASN↓, 5,   FDG↓, 1,   GAPDH↓, 2,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↓, 1,   GlucoseCon↓, 12,   GlutaM↓, 1,   GlutMet↓, 1,   Glycolysis↓, 36,   Glycolysis↝, 1,   GSK‐3β↓, 14,   GSK‐3β↑, 5,   p‑GSK‐3β↓, 1,   H2S↑, 1,   HK1↓, 1,   HK2↓, 18,   HMG-CoA↓, 1,   IDH1↓, 1,   lactateProd↓, 14,   lactateProd↑, 1,   LDHA↓, 3,   LDL↓, 4,   lipoGen↓, 1,   MCT4↓, 2,   NADH:NAD↓, 1,   NADPH↓, 4,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 8,   PDK3↑, 1,   PFK1↓, 1,   PKM2↓, 11,   SCD1↓, 1,   SIRT1↓, 8,   SIRT1↑, 8,   SIRT2↓, 1,   SIRT2↑, 1,   SREBP1/SREBF1↓, 1,   TCA↓, 2,   TCA↑, 1,   TCA↝, 1,   UGDH↓, 2,   Warburg↓, 11,  

Cell Death(tgid=5) ⓘ

AIF↑, 13,   APAF1↑, 4,   Apoptosis?, 1,   Apoptosis↓, 2,   Apoptosis↑, 190,   mt-Apoptosis↑, 2,   ASC↓, 1,   BAD↓, 2,   BAD↑, 4,   Bak↓, 1,   Bak↑, 6,   BAX↓, 3,   BAX↑, 84,   Bax:Bcl2↓, 1,   Bax:Bcl2↑, 20,   Bcl-2↓, 85,   Bcl-2↑, 4,   Bcl-xL↓, 20,   BID↓, 1,   BID↑, 3,   p‑BID↓, 1,   BIM↓, 1,   BIM↑, 4,   BNIP3↑, 1,   BNIP3↝, 1,   BOK↑, 1,   Casp↑, 39,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 3,   Casp12?, 1,   Casp12↑, 1,   cl‑Casp12↑, 1,   Casp3↓, 2,   Casp3↑, 101,   Casp3↝, 1,   cl‑Casp3↑, 13,   cl‑Casp3⇅, 1,   proCasp3↑, 1,   Casp6↑, 1,   Casp7↑, 14,   cl‑Casp7↑, 2,   Casp8↑, 23,   cl‑Casp8↑, 2,   proCasp8↑, 1,   pro‑Casp8↑, 1,   Casp9↓, 1,   Casp9↑, 61,   cl‑Casp9↑, 6,   proCasp9↓, 1,   cFLIP↓, 3,   Cyt‑c↓, 3,   Cyt‑c↑, 56,   Cyt‑c↝, 1,   Diablo↑, 3,   DR5↑, 19,   Endon↑, 1,   FADD↑, 5,   Fas↑, 11,   FasL↓, 1,   FasL↑, 6,   Ferroptosis↑, 20,   GranB/GZMB↓, 1,   GranB/GZMB↝, 1,   GSDME↑, 1,   IAP1↓, 4,   IAP2/BIRC3↓, 2,   IAP2/BIRC3↑, 1,   ICD↑, 1,   iNOS↓, 15,   Mcl-1↓, 18,   Mcl-1↑, 1,   p‑Mcl-1↓, 1,   MDM2↓, 8,   MDM2↑, 2,   p‑MDM2↓, 1,   MOMP↓, 1,   MOMP↑, 4,   NAIP↓, 1,   Necroptosis↑, 2,   necrosis↑, 4,   NOXA↑, 4,   p38↓, 2,   p38↑, 14,   p‑p38↓, 1,   p‑p38↑, 2,   Paraptosis↑, 1,   Perforin↝, 1,   pS2/TFF1↓, 1,   PUMA↓, 1,   PUMA↑, 5,   Pyro↑, 3,   RIP3↑, 1,   survivin↓, 37,   TRAIL↑, 2,   TRAIL⇅, 1,   TRAILR↑, 1,   TumCD↓, 2,   TumCD↑, 17,   XIAP↓, 20,   XIAP↑, 1,   YAP/TEAD↓, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 2,   Akt↓, 126,   Akt↑, 6,   p‑Akt↓, 31,   AKT1↓, 3,   Akt2↓, 1,   AMPKα↑, 1,   BRAF↓, 1,   CaMKII ↓, 1,   CIP2A↓, 1,   CK2↓, 2,   cMET↓, 3,   cSrc↓, 2,   DDIT4↑, 1,   DYRK1B↓, 1,   EF-1α↓, 1,   EGFR↓, 30,   EGFR↑, 2,   p‑EGFR↓, 1,   ERK↓, 42,   ERK↑, 5,   p‑ERK↓, 12,   FGFR1↓, 3,   FGFR2↓, 1,   FOXD3↑, 1,   HER2/EBBR2↓, 7,   HGF/c-Met↓, 3,   Hippo↑, 1,   IGF-1R↓, 3,   IGF-2R↑, 1,   IKKα↓, 3,   p‑IKKα↓, 1,   IκB↓, 1,   IκB↑, 1,   JAK↓, 5,   JAK1↓, 3,   JAK1↑, 1,   JAK2↓, 9,   p‑JAK2↓, 1,   JNK↓, 6,   JNK↑, 16,   p‑JNK↑, 2,   LIMK1↓, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 32,   MAPK↑, 13,   MAPK↝, 2,   p‑MAPK↓, 1,   MARK4↓, 2,   MEK↓, 3,   mTOR↓, 70,   mTOR⇅, 1,   mTOR↝, 2,   p‑mTOR↓, 6,   p‑p70S6↓, 1,   P70S6K↓, 2,   p‑P70S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 98,   PI3K↑, 3,   PI3K↝, 1,   p‑PI3K↓, 4,   p‑PI3K↑, 1,   PKA↓, 2,   PKCδ↓, 7,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 33,   Raf↓, 3,   c-Raf↓, 1,   RAS↓, 11,   RET↓, 1,   RIP1↑, 1,   SHP1↑, 1,   Sp1/3/4↓, 6,   Sp1/3/4↑, 1,   Src↓, 3,   p‑Src↓, 1,   STAT↓, 3,   STAT3↓, 65,   STAT3↑, 3,   p‑STAT3↓, 10,   p‑STAT3↑, 2,   STAT6↓, 3,   p‑STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↓, 1,   ATF4↑, 6,   ATF4↝, 1,   CBP↓, 2,   cJun↓, 3,   cJun↑, 1,   p‑cJun↑, 1,   cMyc↓, 34,   cMyc↑, 1,   p‑cMyc↑, 1,   DNMT1↓, 7,   DNMT3A↓, 2,   DNMTs↓, 7,   EZH2↓, 5,   FOXM1↓, 4,   FOXO1↓, 2,   FOXO1↑, 2,   FOXO3↓, 1,   FOXO3↑, 4,   FOXO3↝, 1,   FOXO4↑, 2,   H3↓, 2,   H3↑, 2,   ac‑H3↑, 1,   H4↓, 1,   H4↑, 2,   HATs↓, 4,   HATs↑, 4,   HDAC↓, 27,   HDAC1↓, 8,   HDAC10↓, 1,   HDAC2↓, 6,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC8↓, 2,   HES1↓, 1,   miR-106b↓, 2,   miR-107↑, 1,   miR-124-3p↓, 1,   miR-139-5p↑, 1,   miR-155↓, 2,   miR-19b↓, 2,   miR-200b↑, 1,   miR-203↑, 1,   miR-21↓, 7,   miR-218↑, 1,   miR-224↓, 1,   miR-25-5p↓, 1,   miR-27a-3p↓, 1,   miR-29b↓, 1,   miR-30a-5p↑, 1,   miR-339-5p↝, 1,   miR-340↓, 1,   miR-34a↓, 2,   miR-34a↑, 6,   miR-375↑, 1,   miR-384↑, 1,   miR-422a↑, 1,   miR-590-3p↑, 1,   MTA2↓, 1,   Myc↓, 5,   MYCN↓, 1,   OCT4↓, 9,   other↓, 2,   other↑, 8,   other↝, 40,   other∅, 1,   PhotoS↑, 3,   SD↑, 1,   sonoS↑, 1,   SOX2↓, 6,   SOX4↓, 2,   SOX4↑, 1,   SOX9?, 1,   tumCV?, 1,   tumCV↓, 25,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 15,   cl‑CHOP/DDIT3↑, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↓, 1,   eIF2α↑, 4,   p‑eIF2α↑, 2,   ER Stress↓, 1,   ER Stress↑, 34,   GRP78/BiP?, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 6,   GRP78/BiP↝, 1,   HSP27↝, 1,   HSP70/HSPA5↓, 2,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 12,   PERK↑, 8,   Proteasome↓, 1,   UPR↑, 6,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   ATG7↑, 2,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 8,   CTSK↓, 1,   LAMP1?, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B-II↑, 2,   LC3II↓, 2,   LC3II↑, 14,   p62↓, 5,   p62↑, 3,   PARK2↑, 1,   SESN2↑, 2,   TFEB↑, 1,   TumAuto↓, 2,   TumAuto↑, 38,   TumAuto⇅, 1,   TumAuto↝, 2,  

DNA Damage & Repair(tgid=10) ⓘ

APE1/APEX1↓, 1,   ATM?, 1,   ATM↑, 2,   BRCA1↓, 2,   p‑BRCA1↑, 1,   DFF45↓, 1,   DNAdam↓, 3,   DNAdam↑, 51,   DNAdamC↑, 1,   DNArepair↓, 3,   DNArepair↑, 1,   ERCC3↑, 1,   m-FAM72A↓, 1,   G9a↓, 1,   hTERT/TERT↓, 13,   MGMT↓, 2,   NKX3.1↓, 1,   p16↑, 2,   P53?, 1,   P53↓, 4,   P53↑, 72,   p‑P53↑, 1,   p53 Wildtype↓, 1,   p53 Wildtype↑, 1,   p53 Wildtype∅, 1,   p73↑, 1,   PARP↓, 1,   PARP↑, 19,   cl‑PARP↓, 2,   cl‑PARP↑, 49,   PARP1↑, 1,   PCNA↓, 17,   SIRT6↑, 1,   Telomerase↓, 16,   TOP1?, 1,   TOP1↓, 11,   TOP2↓, 6,   TOP2↑, 2,   TP53↑, 4,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↓, 1,   γH2AX↑, 3,   γH2AX↝, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 8,   CDK1↑, 5,   CDK2↓, 30,   CDK2↑, 1,   CDK4↓, 39,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 11,   CDK6↑, 1,   CDK7↓, 1,   CDK8↓, 1,   CDKN1C/p57↓, 1,   CDKN1C/p57↑, 1,   CHK1↓, 2,   p‑CHK1↑, 1,   Chk2↓, 2,   Cyc↓, 1,   cycA1/CCNA1↓, 3,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 21,   CycB/CCNB1↑, 4,   cycD1/CCND1↓, 54,   cycD1/CCND1↑, 2,   p‑cycD1/CCND1↓, 1,   CycD3↓, 1,   cycE/CCNE↓, 13,   E2Fs↓, 5,   E2Fs↑, 1,   Ki-67↓, 27,   mitA↑, 3,   p19↑, 1,   P21?, 1,   P21↓, 1,   P21↑, 42,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 16,   pRB↓, 1,   RB1↑, 1,   p‑RB1↓, 5,   Securin↓, 1,   TubPol↓, 1,   TumCCA↓, 6,   TumCCA↑, 169,   UBE2C↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 7,   ALDH1A1↓, 2,   ALDH1A3↓, 1,   Axin2↑, 1,   BMP7/OP1↓, 1,   BMPs↑, 2,   CD133↓, 3,   CD133↑, 1,   CD34↓, 1,   cFos↓, 4,   cFos↑, 1,   cMYB↓, 2,   CSCs?, 1,   CSCs↓, 43,   Diff↑, 2,   EIF4E↓, 1,   FGF↓, 3,   Gli↓, 2,   Gli1↓, 9,   HH↓, 10,   HH∅, 1,   HMGCR↓, 1,   IGF-1↓, 6,   IGFBP1↑, 1,   IGFBP3↑, 1,   JAG1↓, 1,   Ki-67↓, 27,   Let-7↑, 3,   LRP6↓, 1,   mTORC1↓, 5,   Nanog↓, 10,   Nestin↓, 2,   NICD↓, 1,   NOTCH↓, 16,   NOTCH1↓, 12,   NOTCH1↑, 4,   NOTCH3↓, 2,   p300↓, 2,   PTCH1↓, 1,   PTCH2↓, 1,   Shh↓, 8,   Smo↓, 3,   STAT1↓, 1,   TAZ↓, 1,   TumCG↓, 70,   TumCG↑, 3,   TumCP?, 1,   TumCP↓, 130,   TumCP↑, 5,   TumCP⇅, 1,   tyrosinase↓, 2,   Wnt↓, 41,   Wnt↝, 1,   Wnt/(β-catenin)↓, 2,   Zn2+↑, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   annexin II↓, 1,   AP-1↓, 10,   ASAP2↓, 1,   AXL↓, 1,   BACH1↓, 1,   CA↓, 1,   Ca+2↓, 3,   Ca+2↑, 18,   Ca+2↝, 2,   Cav1↓, 1,   Cdc42↓, 1,   Cdc42↑, 1,   CTNNB1↓, 1,   E-cadherin↓, 9,   E-cadherin↑, 30,   EMT↓, 64,   EMT↑, 1,   EpCAM↓, 2,   FAK↓, 11,   FAK↑, 1,   p‑FAK↓, 4,   fascin↓, 1,   Fibronectin↓, 1,   GLI2↓, 1,   hnRNPA1↓, 1,   ITGB1↓, 3,   ITGB3↓, 1,   ITGB6↓, 1,   KRAS↓, 2,   LAMs↓, 2,   MALAT1↓, 3,   MET↓, 1,   p‑MET↓, 1,   MMP-10↓, 1,   MMP1↓, 5,   MMP13↓, 4,   MMP15↓, 1,   MMP16↓, 1,   MMP2↓, 77,   MMP2↑, 1,   MMP3↓, 7,   MMP7↓, 9,   MMP9↓, 90,   MMP9↑, 4,   MMPs↓, 35,   MUC4↓, 2,   N-cadherin↓, 20,   PDGF↓, 5,   Rac1↓, 2,   RECK↑, 1,   Rho↓, 4,   Rho↑, 1,   ROCK1↓, 5,   ROCK1↑, 1,   Slug↓, 7,   Smad1↓, 1,   SMAD3↓, 1,   Snail↓, 12,   TET1?, 1,   TET1↑, 5,   TGF-β↓, 10,   TIMP1↓, 1,   TIMP1↑, 13,   TIMP2↑, 11,   TIMP3↑, 1,   TRIB3↑, 3,   TSC1↑, 1,   TumCA↓, 4,   TumCI↓, 69,   TumCMig↓, 55,   TumCMig↑, 1,   TumMeta?, 1,   TumMeta↓, 86,   TumMeta↑, 7,   TumPF↓, 1,   Twist↓, 14,   TXNIP↑, 1,   Tyro3↓, 1,   uPA↓, 14,   uPAR↓, 1,   Vim↓, 25,   Vim↑, 1,   Zeb1↓, 9,   ZEB2↓, 2,   α-SMA↓, 2,   α-SMA↑, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 44,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 117,   angioG↑, 2,   CD31/PECAM-1↓, 6,   EGR1↑, 1,   EGR4↓, 1,   Endoglin↑, 2,   HIF-1↓, 7,   Hif1a↓, 62,   Hif1a↝, 1,   LOX1↓, 2,   NO↓, 4,   NO↑, 1,   PGI2↓, 1,   VCAM-1↓, 3,   VEGF↓, 100,   VEGF↑, 1,   VEGFR1↓, 3,   VEGFR2/KDR/Flk1↓, 8,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 16,   CLDN1↓, 4,   CLDN1↑, 1,   CX43/GJA1↓, 1,   EPR↑, 16,   GLUT1↓, 8,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↓, 2,   IBI↑, 1,   MMP↓, 80,   MMP↑, 2,   MPT↑, 6,   NHE1↓, 2,   OATPs↓, 2,   OCLN↑, 1,   TJ↓, 1,   TJ↑, 1,   TRPV1↑, 3,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 3,   CD4+↓, 1,   CD4+↑, 1,   CD44↓, 9,   CD47↓, 1,   CD8+↑, 2,   p‑cDC2↓, 1,   COX1↓, 2,   COX1↑, 1,   COX2/PTGS2↓, 71,   COX2/PTGS2↑, 5,   CXCL12↓, 1,   CXCR4↓, 9,   Dectin1↝, 1,   DR4↑, 5,   FOXP3↓, 2,   FOXP3↑, 1,   Gal-3↓, 1,   GM-CSF↓, 1,   HCAR1↓, 1,   HLA↑, 1,   HLA-I/II↑, 1,   HMGB1↓, 2,   ICAM-1↓, 5,   IFN-γ↓, 1,   IFN-γ↑, 3,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 6,   IL1↑, 1,   IL10↓, 4,   IL10↑, 3,   IL12↓, 1,   IL12↑, 1,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 20,   IL1β↑, 1,   IL2↓, 4,   IL2↑, 7,   IL4↑, 1,   IL6↓, 38,   IL8↓, 10,   Imm↑, 18,   Imm↝, 2,   INF-γ↓, 1,   Inflam↓, 42,   IRAK1↓, 1,   LRIG1↑, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 3,   MCT1↓, 2,   MDSCs↓, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   mPGES-1↓, 1,   NAF1↓, 1,   NF-kB?, 1,   NF-kB↓, 141,   NF-kB↑, 4,   p‑NF-kB↓, 1,   p‑NF-kB↑, 2,   NK cell↑, 7,   NLRP3↓, 3,   NLRP3↑, 2,   NOD1↓, 1,   p65↓, 4,   p‑p65↓, 2,   PD-1↓, 3,   PD-1↝, 2,   PD-L1↓, 11,   PGE1↓, 1,   PGE2↓, 22,   PSA↓, 12,   SOCS-3↓, 1,   T-Cell↑, 1,   TCF↓, 1,   Th1 response↑, 1,   TLR4↓, 5,   TLR4↝, 1,   TNF-α↓, 37,   TNF-α↑, 5,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   Treg lymp↓, 3,  

Cellular Microenvironment(tgid=17) ⓘ

pH↓, 1,   pH↑, 1,   e-pH↑, 2,   i-pH↓, 1,   TAMS↓, 1,   TAMS↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   PTN↓, 1,   SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

2/16-OHE1↑, 1,   2/16-OHE1↝, 1,   AhR↓, 1,   AhR↓, 1,   AR↓, 17,   AR↝, 2,   AR-FL↓, 1,   AR-V7↑, 1,   COMT↓, 2,   CYP17A1↓, 1,   CYP19↓, 2,   ENL↑, 1,   ER(estro)↓, 2,   ERα/ESR1↓, 1,   Estro↝, 1,   FGF21↓, 1,   FKBP5↓, 1,   PPARα↓, 2,   PPARγ↓, 1,   PPARγ↑, 3,   RANKL↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 176,   BioAv↑, 237,   BioAv⇅, 2,   BioAv↝, 74,   BioEnh?, 1,   BioEnh↑, 7,   CBR1↓, 1,   chemoR↓, 2,   ChemoSen?, 1,   ChemoSen↓, 2,   ChemoSen↑, 197,   ChemoSen⇅, 2,   CompStab?, 1,   CompStab↓, 7,   CompStab↑, 7,   CompStab↝, 3,   CYP1A1↓, 6,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP1A2↑, 2,   CYP2A3/CYP2A6↓, 1,   CYP2C9↓, 1,   CYP2E1↑, 1,   CYP3A2↓, 1,   CYP3A4↓, 4,   DDS↑, 10,   Dose?, 4,   Dose↓, 4,   Dose↑, 16,   Dose↝, 90,   Dose∅, 11,   DrugR↓, 1,   eff?, 1,   eff↓, 28,   eff↑, 129,   eff⇅, 1,   eff↝, 13,   eff∅, 3,   GSTA1↑, 2,   GSTM1↑, 1,   GSTZ1↓, 1,   GSTZ1↝, 1,   Half-Life↓, 33,   Half-Life↑, 12,   Half-Life↝, 36,   Half-Life∅, 5,   MDR1↓, 10,   MRP↓, 1,   MRP1/ABCC1↓, 5,   MRP1/ABCC1↑, 1,   MRP1/ABCC1↝, 1,   P-gp/ABCB1↓, 22,   P-gp/ABCB1↑, 3,   P-gp/ABCB1⇅, 1,   P450↓, 4,   RadioS?, 1,   RadioS↑, 69,   RadioS↝, 1,   selectivity?, 1,   selectivity↑, 86,   selectivity↝, 1,   selectivity∅, 1,   Synergy↑, 112,   Synergy↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 6,   ALAT↑, 1,   ALP↓, 2,   AR↓, 17,   AR↝, 2,   ascitic↓, 1,   AST↓, 4,   AST↑, 1,   BMD↑, 1,   BP↓, 2,   BRAF↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CEA↓, 2,   CEC↝, 1,   CRP↓, 2,   E6↓, 2,   E7↓, 2,   EGFR↓, 30,   EGFR↑, 2,   p‑EGFR↓, 1,   ERα/ESR1↓, 1,   EZH2↓, 5,   Ferritin↓, 1,   FOXM1↓, 4,   HER2/EBBR2↓, 7,   hTERT/TERT↓, 13,   IL6↓, 38,   KRAS↓, 2,   LDH↓, 5,   LDH↑, 1,   LDH↝, 1,   Myc↓, 5,   NOS2↓, 1,   NOS2↑, 1,   NSE↓, 1,   PD-L1↓, 11,   PSA↓, 12,   TF-Ag↓, 1,   TG/TAG↓, 1,   TP53↑, 4,   TRIB3↑, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiArt↑, 1,   AntiCan↓, 3,   AntiCan↑, 79,   AntiCan∅, 1,   antiD↑, 1,   AntiDiabetic↑, 1,   antiNeop↑, 3,   antiPs↑, 1,   AntiTum↑, 29,   cachexia↓, 3,   cardioP↑, 22,   CardioT↓, 1,   CardioT↑, 1,   chemoP↑, 41,   chemoPv↑, 22,   ChemoSideEff↓, 7,   cognitive?, 1,   cognitive↑, 4,   fatigue↓, 2,   hepatoP↓, 3,   hepatoP↑, 14,   memory↑, 4,   Mucositis↓, 1,   neuroP↑, 13,   NP/CIPN↓, 3,   NP/CIPN↑, 1,   Obesity↓, 1,   ORR↑, 1,   OS↑, 18,   OS↝, 1,   OS∅, 1,   Pain↓, 5,   PFS↓, 1,   PFS↑, 1,   PFS∅, 1,   QoL↑, 5,   QoL↝, 1,   radioP↑, 10,   Remission↑, 2,   RenoP↑, 5,   Risk↓, 29,   Risk↑, 1,   Sleep↑, 1,   toxicity↓, 38,   toxicity↑, 8,   toxicity⇅, 2,   toxicity↝, 21,   toxicity∅, 4,   TumVol↓, 20,   TumW↓, 7,   Weight↑, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiViral↑, 1,   Bacteria↓, 1,   Dectin1↝, 1,   GutMicro↑, 11,   GutMicro↝, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 2,   Ingr↝, 3,  
Total Targets: 1036

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 1,   antiOx?, 1,   antiOx↓, 16,   antiOx↑, 188,   ARE↑, 4,   ARE↝, 1,   Catalase↓, 1,   Catalase↑, 67,   Fenton↓, 2,   GPx↓, 1,   GPx↑, 53,   GPx1↑, 2,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 65,   GSR↑, 9,   GSTs↓, 3,   GSTs↑, 17,   H2O2↓, 7,   H2O2↑, 1,   H2O2∅, 2,   HDL↑, 5,   HDL∅, 1,   HNE↓, 1,   HO-1↓, 2,   HO-1↑, 46,   HO-2↓, 1,   Iron↓, 1,   Keap1↓, 2,   Keap1↑, 2,   Keap1↝, 1,   lipid-P↓, 57,   mt-lipid-P↓, 1,   MDA↓, 51,   MPO↓, 11,   NADH↓, 1,   NOX↓, 1,   NQO1↑, 10,   NQO1↝, 1,   NQO1∅, 1,   Nrf1↑, 2,   NRF2?, 1,   NRF2↓, 3,   NRF2↑, 74,   NRF2⇅, 1,   NRF2↝, 1,   Prx↑, 1,   RNS↓, 5,   ROS?, 1,   ROS↓, 222,   ROS↑, 4,   ROS⇅, 4,   ROS∅, 2,   mt-ROS?, 1,   selenoP↑, 4,   SOD↓, 5,   SOD↑, 96,   mt-SOD↑, 1,   SOD1↑, 5,   SOD2↑, 3,   TAC↑, 7,   TBARS↓, 2,   Thiols↑, 1,   Trx↑, 2,   Trx1↑, 1,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 5,   VitE↑, 4,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   IronCh↑, 13,   IronCh↝, 1,   Mets↝, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 2,   compII↑, 2,   compIII↑, 2,   compIV↑, 1,   DRP1/DNM1L↓, 1,   ETC↑, 1,   Insulin↓, 2,   Insulin↑, 4,   Insulin↝, 1,   MFN2↑, 1,   mtDam↓, 4,   OCR↓, 1,   OCR↑, 2,   OXPHOS↑, 1,   PGC-1α↑, 4,   PGC-1α↝, 1,   PINK1↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   15-LOX/ALOX15↓, 1,   5LO↓, 5,   ACC↓, 1,   Acetyl-CoA↑, 1,   adiP↑, 1,   ALAT↓, 18,   ALAT∅, 2,   AMPK↓, 2,   AMPK↑, 16,   AMPK↝, 1,   ATP↓, 1,   ATP↑, 11,   Buty↑, 1,   cAMP↑, 2,   CRM↑, 1,   cytoP450↓, 1,   DHODH↓, 1,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 1,   FFA/NEFA↓, 1,   G6PD↑, 1,   glucose↓, 8,   glucose↝, 4,   GlucoseCon↑, 5,   GlutMet↑, 1,   glyC↓, 1,   Glycolysis↓, 1,   GSK‐3β↓, 13,   GSK‐3β↑, 3,   p‑GSK‐3β↑, 1,   H2S↑, 1,   HMG-CoA↓, 2,   LDHA↑, 1,   LDL↓, 15,   lipidLev↓, 6,   lipoGen↓, 1,   NAD↓, 1,   NAD↑, 2,   NADH:NAD↑, 1,   NADPH↓, 3,   NADPH↑, 4,   PDK1 / PDPK1↓, 1,   PFK↓, 1,   PLA2↓, 2,   SCFAs↑, 1,   SIRT1↑, 21,   SIRT1↝, 1,   SIRT2↑, 1,   SREBF2↓, 1,   SREBF2⇅, 1,   SREBP1/SREBF1↓, 1,   SREBP1/SREBF1↑, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Apoptosis↓, 15,   ASC↓, 1,   BAX↓, 11,   Bax:Bcl2↓, 2,   Bcl-2↓, 3,   Bcl-2↑, 9,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 24,   cl‑Casp3↓, 1,   Casp6↓, 1,   Casp8↓, 1,   Casp9↓, 11,   Casp9↑, 1,   Cyt‑c↓, 5,   Cyt‑c∅, 1,   Fas↓, 1,   Ferroptosis↓, 2,   GranB/GZMB↓, 1,   iNOS↓, 27,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 3,   Pyro↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 5,   Akt↑, 19,   Akt↝, 1,   p‑Akt↓, 1,   p‑Akt↑, 3,   Akt2↓, 1,   AMPKα↑, 1,   CREB↑, 4,   p‑CREB↑, 1,   ERK↓, 6,   ERK↑, 5,   p‑ERK↑, 3,   HGF/c-Met↑, 1,   IGF-1R↓, 1,   IKKα↓, 2,   JAK↓, 2,   JAK2↓, 1,   JAK2↑, 1,   JNK↓, 7,   p‑JNK↓, 3,   MAPK↓, 17,   MAPK↑, 2,   MAPK↝, 2,   mTOR↓, 3,   mTOR↑, 5,   mTOR↝, 1,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 5,   PI3K↑, 10,   PI3K↝, 1,   PKCδ↓, 2,   PKCδ↑, 2,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 1,   STAT↓, 2,   STAT3↓, 3,   STAT3↑, 3,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ac-histone H3↑, 1,   AntiThr↑, 7,   ATF2↑, 1,   ATF4↓, 3,   DNMT1↓, 1,   FOXO↑, 1,   FOXO3↑, 1,   H3↑, 1,   H4↑, 1,   HATs↓, 1,   HDAC↓, 3,   HDAC↑, 2,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 2,   HOTAIR↑, 1,   other?, 3,   other↓, 10,   other↑, 23,   other↝, 41,   PhotoS↑, 1,   SOX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 4,   CHOP/DDIT3↑, 1,   eIF2α↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 7,   GRP78/BiP↓, 4,   GRP78/BiP↑, 2,   GRP94↑, 1,   HSP70/HSPA5↑, 3,   HSP70/HSPA5↝, 1,   HSP90↑, 1,   HSPs↑, 2,   IRE1↓, 1,   PERK↓, 1,   UPR↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 5,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↓, 2,   LC3II↑, 1,   MitoP↓, 1,   p62↑, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   DNAdam↓, 13,   DNArepair↑, 3,   P53↓, 3,   PARP1↓, 1,   PCNA↓, 2,   Telomerase↓, 1,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   E2Fs↑, 1,   GADD34↓, 1,   Ki-67↓, 2,   Ki-67↑, 1,   P21↓, 1,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,   Choline↑, 2,   Diff↝, 1,   FGF↑, 1,   GH↑, 1,   HH↓, 1,   HMGCR↓, 1,   IGF-1↓, 1,   IGF-1↑, 1,   IGFBP3↑, 1,   Ki-67↓, 2,   Ki-67↑, 1,   Nestin↑, 1,   neuroG↑, 8,   NOTCH1↑, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 3,   AntiAg↑, 25,   AP-1↓, 7,   BACH1↓, 1,   Ca+2↓, 3,   Ca+2↑, 2,   Ca+2↝, 1,   Cartilage↑, 2,   COL1↓, 3,   Fibrosis↓, 1,   LRP1↑, 1,   MLC2/MYL9↝, 1,   MMP13↓, 2,   MMP2↓, 2,   MMP2↑, 2,   MMP3↓, 1,   MMP9↓, 10,   MMPs↓, 4,   MUC1↑, 1,   N-cadherin↑, 1,   Rho↓, 1,   ROCK1↓, 1,   p‑SMAD2↓, 2,   p‑SMAD3↓, 1,   p‑SMAD3↑, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 5,   TGF-β↑, 2,   TGF-β1↓, 2,   TGF-β1↑, 1,   TIMP1↓, 1,   TregCell↑, 1,   TXNIP↓, 1,   uPA↑, 1,   α-SMA↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 3,   CD31/PECAM-1↑, 1,   E-sel↓, 1,   NO↓, 20,   NO↑, 3,   TXA2↓, 2,   VCAM-1↓, 8,   VEGF↓, 2,   VEGF↑, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↓, 7,   BBB↑, 53,   BBB↝, 3,   BBB∅, 3,   EPR↑, 1,   GastroP↑, 6,   GLUT2↑, 2,   GLUT3↑, 1,   GLUT4↑, 3,   H+/K+-ATPase↓, 1,   IBI↑, 5,   memfluid↑, 2,   MMP↓, 1,   MMP↑, 16,   MMP∅, 1,   MUC19↓, 1,   MUC2↓, 1,   OCLN↓, 1,   OCLN↝, 1,   TJ↑, 3,   TRPA1↑, 1,   TRPV1↑, 2,   TRPV3↑, 2,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   CB2 / CNR2↑, 1,   CD4+↑, 2,   CD8+↑, 1,   COX1↓, 9,   COX2/PTGS2↓, 57,   COX2/PTGS2↑, 1,   CXCR4↓, 1,   HMGB1↓, 2,   ICAM-1↓, 5,   IFN-γ↓, 5,   IFN-γ↑, 1,   IL1↓, 5,   IL10↓, 5,   IL10↑, 6,   IL12↓, 2,   IL17↓, 4,   IL18↓, 3,   IL1α∅, 1,   IL1β↓, 47,   IL1β∅, 1,   IL2↓, 5,   IL22↓, 1,   IL33↓, 1,   IL4↓, 5,   IL4↑, 1,   IL5↓, 2,   IL6↓, 56,   IL6↑, 3,   IL8↓, 12,   IL8↑, 1,   IL8∅, 1,   Imm↓, 2,   Imm↑, 20,   Imm⇅, 1,   Imm↝, 2,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 217,   Inflam↑, 6,   IRF3↓, 1,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 5,   MCP1/CCL2↑, 1,   MCP1/CCL2∅, 1,   MCT1↓, 1,   MIP‑1α/CCL3↓, 1,   MyD88↓, 1,   NeuroI↓, 3,   NF-kB↓, 77,   NF-kB↑, 3,   p‑NF-kB↓, 1,   NLRP3↓, 14,   NLRP3↑, 2,   p65↓, 2,   PGE2↓, 19,   RAGE↓, 3,   RANTES↓, 1,   TLR2↓, 4,   TLR3↓, 1,   TLR4↓, 9,   TLR4↑, 1,   TNF-α↓, 79,   TNF-α↑, 2,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 6,   Ach↑, 6,   AChE↓, 30,   AChE↑, 2,   ADAM10↑, 3,   BChE↓, 9,   BDNF↓, 1,   BDNF↑, 19,   ChAT↑, 6,   GABA↑, 5,   MAOA↓, 6,   MAOA↝, 1,   MAOB↓, 2,   monoA↑, 1,   NGF↑, 6,   PSD95↑, 4,   SNAP25↑, 2,   TPH1↓, 1,   TrkB↑, 4,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 7,   APOE4↓, 1,   APP↓, 6,   cl‑APP↑, 1,   Aβ↓, 54,   Aβ42↓, 4,   BACE/β-secretase↓, 15,   PSEN1/PS1↑, 1,   tau↓, 16,   p‑tau↓, 7,   XO↓, 1,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   cortisol↑, 1,   CYP19↓, 2,   DHT↑, 1,   GLP-1R↑, 1,   GR↑, 1,   PPARα↑, 4,   PPARγ↓, 3,   PPARγ↑, 8,   p‑PPARγ↓, 1,   SHBG↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv?, 2,   BioAv↓, 211,   BioAv↑, 354,   BioAv⇅, 4,   BioAv↝, 171,   BioAv∅, 3,   BioEnh↑, 6,   ChemoSen↑, 4,   CompStab↓, 1,   CompStab↑, 10,   CompStab↝, 3,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 2,   CYP3A2↓, 1,   DDS↑, 1,   Dose?, 4,   Dose↑, 9,   Dose⇅, 2,   Dose↝, 117,   Dose∅, 4,   eff↓, 5,   eff↑, 58,   eff↝, 7,   GSTA1↓, 1,   GSTA1↑, 1,   Half-Life?, 2,   Half-Life↓, 34,   Half-Life↑, 19,   Half-Life↝, 58,   Half-Life∅, 6,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 7,   P450↓, 3,   P450↑, 2,   P450↝, 1,   Synergy↑, 34,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 18,   ALAT∅, 2,   ALB↑, 1,   ALP↓, 4,   anemia↓, 1,   AST↓, 20,   AST∅, 2,   BG↓, 2,   BloodF↑, 7,   BMD↑, 5,   BP↓, 17,   BP↝, 1,   p‑BRCA1↑, 1,   creat↓, 3,   CRP↓, 8,   Ferritin↓, 1,   Ferritin↑, 1,   HemoG↑, 1,   HOMA↓, 1,   hs-CRP↓, 3,   IL6↓, 56,   IL6↑, 3,   IRes↓, 1,   IRes↑, 2,   IRes↝, 1,   LDH↓, 6,   NOS2↓, 2,   RAGE↓, 3,   RBC↑, 1,   TC↓, 2,   TG/TAG↓, 2,   TMAO↓, 1,   Urea↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 5,   AntiAge↑, 12,   antiAll↑, 19,   AntiArt↑, 8,   AntiCan↓, 1,   AntiCan↑, 35,   antiCG↝, 1,   AntiDiabetic↓, 2,   AntiDiabetic↑, 48,   AntiMyl↑, 1,   antiPs↑, 4,   AntiTum↓, 2,   AntiTum↑, 6,   Appetite↓, 1,   cardioP↓, 2,   cardioP↑, 95,   cardioP⇅, 1,   CardioT↓, 2,   chemoP↑, 15,   chemoPv↑, 13,   cognitive↓, 2,   cognitive↑, 76,   cognitive↝, 1,   cognitive∅, 2,   cough?, 1,   diuretic↑, 3,   hepatoP↓, 3,   hepatoP↑, 67,   Learn↑, 5,   memory↓, 1,   memory↑, 60,   motorD↓, 1,   motorD↑, 10,   Mucositis↓, 2,   neuroP↓, 2,   neuroP↑, 168,   neuroP↝, 1,   Obesity↓, 26,   OS↑, 4,   Pain↓, 11,   radioP↑, 9,   RenoP↓, 1,   RenoP↑, 20,   RenoP↝, 1,   Risk↓, 6,   Risk↑, 3,   Sleep↑, 2,   SoreThr?, 1,   Strength↑, 2,   Stroke↓, 16,   toxicity?, 2,   toxicity↓, 75,   toxicity↑, 13,   toxicity⇅, 1,   toxicity↝, 27,   toxicity∅, 12,   Weight↓, 4,   Weight↝, 1,   Wound Healing↑, 8,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 20,   AntiFungal↑, 7,   AntiP↑, 1,   AntiViral↑, 16,   Bacteria↓, 40,   Diar↓, 2,   GutMicro↑, 40,   GutMicro↝, 2,   Sepsis↓, 4,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,   Ingr↑, 5,   Ingr↝, 9,  
Total Targets: 622

Scientific Paper Hit Count for: BioAv, bioavailability
49 Curcumin
21 Sulforaphane (mainly Broccoli)
20 chitosan
20 Quercetin
20 EGCG (Epigallocatechin Gallate)
18 Baicalein
18 Chlorogenic acid
17 Resveratrol
15 Berberine
15 Selenium NanoParticles
15 Chrysin
15 Luteolin
15 Lycopene
14 Apigenin (mainly Parsley)
14 Pterostilbene
13 Kaempferol
12 Thymoquinone
11 Silymarin (Milk Thistle) silibinin
11 Honokiol
10 Alpha-Lipoic-Acid
10 Rosmarinic acid
10 Magnolol
9 Astaxanthin
9 borneol
9 Carvacrol
9 Morin
9 Urolithin
8 Broccoli
8 Capsaicin
8 Crocetin
8 Diindolylmethane
8 Emodin
8 Ferulic acid
8 Fucoidan
8 Piperlongumine
7 Allicin (mainly Garlic)
7 Artemisinin
7 Betulinic acid
7 Hydroxycinnamic-acid
7 Piperine
7 Fisetin
7 Flaxseed/Linseed
7 HydroxyTyrosol
7 Isoliquiritigenin
7 isoquercitrin
7 Phenethyl isothiocyanate
6 Silver-NanoParticles
6 Ashwagandha(Withaferin A)
6 Biochanin A
6 Rutin
6 Propolis -bee glue
6 Ellagic acid
6 Eugenol
5 beta-glucans
5 Baicalin
5 Boswellia (frankincense)
5 Thymol-Thymus vulgaris
5 Centella asiatica / Gotu kola → asiaticoside
5 Cucurbitacin
5 Formononetin
5 SDG/lignans
5 Gallic acid
5 Inositol
5 Naringin
5 Selenite (Sodium)
4 1,8-Cineole
4 5-Hydroxytryptophan
4 Beta-Caryophyllene
4 Boron
4 Caffeic acid
4 Melatonin
4 Celastrol
4 phytic acid, Inositol hexakisphosphate
4 Garcinol
4 Isovitexin
4 Lactoferrin/Talactoferrin
4 Matrine
4 Phenylbutyrate
4 Phycocyanin
4 Vitamin C (Ascorbic Acid)
4 Shikonin
4 Aflavin-3,3′-digallate
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Berbamine
3 Folic Acid, Vit B9
3 Chocolate
3 Cinnamon
3 Coenzyme Q10
3 Copper and Cu NanoParticles
3 Diclofenac
3 Indole-3-carbinol
3 Disulfiram
3 Fenbendazole
3 Gambogic Acid
3 Genistein (soy isoflavone)
3 Glabrescione B
3 Gossypol/AT-101
3 Grapeseed extract
3 Lapatinib
3 Licochalcone A
3 Licorice
3 Lecithin
3 Linalool
3 Lutein
3 Methylene blue
3 mebendazole
3 Metformin
3 Magnetic Fields
3 Niclosamide (Niclocide)
3 Selenium
3 Silicic Acid
3 Spermidine
3 Terpinen-4-ol / Tea Tree Oil
2 3-bromopyruvate
2 Auranofin
2 Astragalus
2 Citric Acid
2 Aspirin
2 Paclitaxel/Taxol
2 Atorvastatin
2 immunotherapy
2 doxorubicin
2 Docetaxel
2 Radiotherapy/Radiation
2 buckwheat sprouts
2 Butyrate
2 Cynanbungeigenin C (CBC) and D (CBD)
2 Chlorophyllin
2 Choline
2 Camptothecin
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Dasatinib/Phyrago
2 Dichloroacetate
2 Deguelin
2 D-limonene
2 Evodiamine
2 flavonoids
2 MCT oil
2 Shilajit/Fulvic Acid
2 Geraniol
2 Ginkgolide B
2 Ginkgetin
2 Hydrogen Gas
2 HydroxyCitric Acid
2 isoflavones
2 isoorientin
2 itraconazole
2 Ivermectin
2 Lapachol
2 Lemongrass Extract/Citral
2 Methyl salicylate / Sweet Birch oil
2 magnetic nanoparticles
2 Magnesium
2 Mushroom Lion’s Mane, Hericium erinaceus
2 nicotinamide adenine dinucleotide
2 Oleuropein
2 Turmerones
2 Ursolic acid
1 Aluminum
1 Anethole/trans-Anethole
1 Aromatherapy
1 Gemcitabine (Gemzar)
1 Aloe anthraquinones
1 xanthohumol
1 beta-carotene(VitA)
1 Bicalutamide
1 Bacopa monnieri
1 α-Bisabolol / Chamomile oil
1 Bullatacin
1 Carnosic acid
1 urea
1 capecitabine
1 Catechins
1 Cat’s Claw
1 Cannabidiol
1 Zinc
1 Citicoline, CDP-Choline
1 irinotecan
1 Polyphenols
1 Cyclopamine
1 Dichloroacetophenone(2,2-)
1 Dandelion Root
1 Echinacea
1 Ginkgo biloba-EGb 761
1 Electrical Pulses
1 Eurycomanone
1 Sesame seeds and Oil
1 Mung Bean Sprouts
1 tamoxifen
1 Gamma-aminobutyric acid
1 Ginkgo biloba
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Geldanamycin
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Arsenic trioxide
1 Graviola
1 Germacranolide sesquiterpene lactone
1 Hibiscus sabdariffa
1 Hyperthermia
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Isobavachalcone
1 iodine
1 Anthocyanins
1 L-Theanine
1 Modified Citrus Pectin
1 Bicarbonate(Sodium)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 Cisplatin
1 Psoralidin
1 Parthenolide
1 enzalutamide
1 Rauwolfia serpentina/Indian Snakeroot
1 salinomycin
1 Chemotherapy
1 Date Fruit Extract
1 cetuximab
1 Tomatine
1 Vitamin B3,Niacin
1 Vitamin D3
1 Vitamin E
1 Vitamin K2
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:792  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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