Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.
Scientific Papers found: Click to Expand⟱
7267- Gink,    Neuroprotective Potential of Biflavone Ginkgetin: A Review
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *ROS↓, *Aβ↓, *Inflam↓, *Dose↝, *cardioP↑, TumCCA↑, Apoptosis↑, TumAuto↑, STAT↓, *Stroke↓,
4301- Gins,    Red Ginseng Inhibits Tau Aggregation and Promotes Tau Dissociation In Vitro
- in-vitro, AD, NA
*p‑tau↓, *eff↑, *Inflam↓,
4003- Gins,    Neuroprotective Potentials of Panax Ginseng Against Alzheimer's Disease: A Review of Preclinical and Clinical Evidences
- Review, adrenal, NA
*neuroP↑, *Inflam↓, *ROS↓, *BACE/β-secretase↓, *PPARγ↑, *Aβ↓, *p‑tau↓, *NF-kB↓, *IL1β↓, *IL6↓, *TNF-α↓, *ROS↓, *CREB↓, *BDNF↑, *memory↑,
4508- GLA,  aLinA,    α-Linolenic and γ-linolenic acids exercise differential antitumor effects on HT-29 human colorectal cancer cells
- in-vitro, Colon, HT29
Apoptosis↑, *Inflam↓, AntiCan↑, lipid-P↑, COX2/PTGS2↝, MKP1↝,
7321- Gos,    The potential roles of gossypol as anticancer agent: advances and future directions
- Review, Var, NA
other↝, BioAv↑, Bcl-2↓, Casp3↑, Casp9↑, MOMP↑, ROS↑, ATP↓, mtDam↑, Apoptosis↑, hTERT/TERT↓, Akt↓, TumAuto↑, LC3‑Ⅱ/LC3‑Ⅰ↑, NRF2↓, ARE↓, ICAM-1↓, CX43/GJA1↓, NF-kB↓, TLR4↓, IL6↓, Inflam↓, CUL5↝, CUL1↝, NOXA↑, TumCI↓, TumCMig↓, TumCA↓, FAK↓, MDM2↓, VEGF↓, angioG↓, HLA-I/II↑, Imm↑, Dose↝, Glycolysis↓, OXPHOS↓,
7335- Gra,    Effect of Annona muricata (Soursop) on Patients with Cancer: A Systematic Review
- Review, Var, NA
TumCG↓, Casp↑, Inflam↓, toxicity↓, other↑, TumCCA↑, Apoptosis↑, TumAuto↑, ATP↓, AIF↑, MMP↓, MOMP↑, Cyt‑c↑, selectivity↑, hepatoP∅,
7325- GSE,    The Effects of a Grape Seed Procyanidin Extract on Cytochrome P450 3A4 Activity and Inflammatory Mediators in the Lungs of Heavy Active and Former Smokers
- in-vitro, Lung, NA
*cardioP↑, *Inflam↓, BioAv↑, TNF-α↓, MIP‑1α/CCL3↓, GranB/GZMB↓, *antiAll↑, *MIP‑1α/CCL3↓,
7324- GSE,    A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention
- Trial, Lung, NA
BioAv↑, toxicity↝, Ki-67↓, miR-106b↓, chemoPv↑, Dose↝, miR-19b↓, PTEN↑, IGF-2R↑, p‑Akt↓, PGE2↓, PGI2↓, COX2/PTGS2↓, Apoptosis↑, TumCP↓, Inflam↓, cardioP↑,
6561- GSL,    Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic-Metabolizing Enzymes
- in-vivo, Nor, NA
*Inflam↓, *antiOx↑, *neuroP↑, *AntiCan↑, *BioAv↝, *Dose↝, *toxicity↓, *Catalase↑, *NADPH↑, *GSR↑, *ALAT∅, *AST∅,
7111- GSL,    In vitro antiinflammatory activity of a new sesquiterpene lactone isolated from Siegesbeckia glabrescens
- in-vitro, Nor, NA
*NO↓, *PGE2↓, *iNOS↓, *COX2/PTGS2↓, *NF-kB↓, *Inflam↓,
4345- H2,    The Benefit of Hydrogen Gas as an Adjunctive Therapy for Chronic Obstructive Pulmonary Disease
- Human, Var, NA
*Inflam↓, *antiOx↑, *ROS↓, *NLRP3↑, *NF-kB↓, *SOD↑, *Catalase↑, *AntiAg↑,
4306- H2,    Molecular Hydrogen as an Emerging Candidate for Preventing Alzheimer’s Disease
- Review, AD, NA
*ROS↓, *memory↑, *neuroP↑, *OS↑, *Inflam↓,
4307- H2,    Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models
- in-vivo, AD, NA
*cognitive↑, *Inflam↓, *ROS↓, *neuroP↑, *memory↑, *BBB↑, *BDNF↑, *TNF-α↓, *Catalase↑, *IL6↓, *Aβ↓, *GABA↓, *Dose↝,
4236- H2,    Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model
- in-vivo, Stroke, NA
*neuroP↑, *Inflam↓, *antiOx↑, *BDNF↑, *Casp3↓,
7484- H2,    Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer's Disease Models
- in-vivo, AD, NA
*Dose↝, *cognitive↑, *ROS↓, *Inflam↓, *neuroP↑, *memory↑, *Catalase↑, *TNF-α↓, *Aβ↓, *GABA↓, *H2O2↓, *GFAP↓, *antiOx↑, *NRF2↑,
7481- H2,  Rad,    Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy
- Trial, Var, NA
Dose↝, CRP↓, NLR↓, IL6↓, AntiTum∅, *toxicity↓, Inflam↓, radioP↑, *IBI↑, *ROS↓,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, Synergy↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑, *antiAll↑,
7483- H2,  Cisplatin,    Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism
- in-vivo, Nor, HK-2
RenoP↑, BHB↑, HMGCS2↑, chemoP↑, *IL2↓, *IL6↓, *MCP1/CCL2↓, *TNF-α↓, *KeyT↝, *Inflam↓, *ROS↓, *MMP↑, *ATP↑, *MFN2↑, *PGC-1α↑, *BUN↓, *creat↓,
7486- H2,    Effects of hydrogen-rich water on blood uric acid in patients with hyperuricemia: A randomized placebo-controlled trial
- Trial, Nor, NA
*eff↑, *uricA↓, *toxicity↓, *antiOx↑, *Inflam↓, *Dose↝, *Dose↝, *Dose↝, *toxicity↓, *Dose↓, *ROS↓,
7487- H2,    A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives
- Review, Nor, NA
*Inflam↓, *antiOx↓, *Stress↓, *Dose↝, *cardioP↑, *GastroP↑, *BBB↑, *eff↑, *toxicity↓, *Dose↝, *hepatoP↑, *ROS↓, *SOD↑, *TBARS↓, *HDL↑, *LDL↓, *Obesity↓, *GSH↑, *TNF-α↓, *GutMicro↑, *DNAdam↓, *γH2AX↓, *p‑p38↓, *NF-kB↓, *antiAll↑,
7488- H2,    Molecular hydrogen therapy: A "democratic" emerging strategy against aging and age-related diseases
- Review, Nor, NA
*antiOx↑, *Inflam↑, *toxicity↓, *AntiAge↑,
7489- H2,    Molecular Hydrogen in the Treatment of Respiratory Diseases
- Review, Asthma, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose↓, *Dose↝, *eff↑, *ROS↓, *RNS↓, *NRF2↑, *HO-1↑, *Fenton↓, *NLRP3↓, *NADPH↓, *NOX4↓, *NOX↓, *MPO↓, *NF-kB↓, *TNF-α↓, *IL6↓, *IL1β↓, *HMGB1↓, *IL4↑, *IL10↑, *M2 MC↑, *Treg lymp↝, *Bcl-2↑, *Bcl-xL↑, *PI3K↑, *Akt↑, *JAK2↑, *STAT3↑, *Dose↑, *CD4+↑, *CD25+↑, *FOXP3↑, *MDA↓, *SOD↑, *Catalase↑, *Casp3↓, *Casp9↓, *TBARS↓, *SpO2↑, *VitE↓, *OS↑, *Weight↑, *DNAdam↓, *PGE2↓, *MCP1/CCL2↓, *lipid-P↓, *TumCP↓, *tumCV↓, *TumCMig↓, *TumCI↓, TumW↓, TumVol↓, selectivity↑, QoL↑, ChemoSen↑, chemoP↑, radioP↑, ROS↑, NLRP3↑, Casp3↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓, *antiAll↑,
7492- H2,  Chemo,    Molecular Hydrogen Protects against Various Tissue Injuries from Side Effects of Anticancer Drugs by Reducing Oxidative Stress and Inflammation
- Review, Var, NA
*ROS↓, *antiOx↑, *Inflam↓, *chemoP↑, AntiCan↑, ChemoSen↑, chemoP↑, *BUN↓, *creat↓, *TUNEL↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *BNP↓, *AST↓, *ALAT↓, *TNF-α↓, *IL1β↓, *IL6↓, *Casp3↓, *Casp9↓, *GPx↑, *E-cadherin↑, *Vim↓, *α-SMA↓, *COL1↓, *cardioP↑, *hepatoP↑, *p‑mTOR↓, *EMT↓, eff∅, *LPS↓, *TLR4↓, radioP↑,
7927- H2,    Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients
- Human, Asthma, NA
*IL8↓, *IL4↓, *IL6↓, *Inflam↓, *Sepsis↓, *Stroke↓, *antiOx↑, *toxicity↓, *antiAll↑,
7928- H2,    Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis
- in-vivo, Asthma, NA
*IL33↓, *NF-kB↓, *IL1RL1/ST2↓, *ILC2↓, *E-cadherin↑, *ZO-1↑, *Inflam↓, *antiAll↑,
7929- H2,    Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma
- in-vivo, Asthma, NA
*IL4↓, *IL5↓, *IL13↓, *TNF-α↓, *AirwayM↓, *MUC5AC↓, *COL3A1↓, *VEGF↓, *NF-kB↓, *Inflam↓, *antiAll↑,
7925- H2,    Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
- in-vivo, Asthma, NA
*Dose?, *IL4↓, *IL13↓, *TNF-α↓, *CXCL15↓, *SOD↑, *MDA↓, *MPO↓, *ROS↓, *antiOx↑, *Inflam↓, *Apoptosis↓, *toxicity↓, *Stroke↓, *Airway↓, *Neut↓, *Eos↓, *BALF-Lym↓, *BALF-Infl↓, *AirwayM↓, *antiAll↑,
7930- H2,    Hydrogen-rich water alleviates asthma airway inflammation by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation
- in-vivo, Asthma, NA
*GutMicro↑, *Inflam↓, *Dose↝, *AirwayM↓, *antiAll↑,
7932- H2,    Hydrogen Gas Inhalation Alleviates Airway Inflammation and Oxidative Stress on Ovalbumin-Induced Asthmatic BALB/c Mouse Model
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *ROS↓, *TAC↑, *IgE↓, *Dose↝, *NLR↓, *IL4↓, *IL5↓, *IL13↓, *GM-CSF↓, *NO↓, *GPx↑, *Eos↓, *antiAll↑,
7933- H2,    Hydrogen inhalation ameliorates lung inflammation in mice with asthma
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *IL4↓, *IL5↓, *IL13↓, *IL10↑, *TGF-β1↑, *IgE↓, *MDA↓, *SOD↑, *Airway↓, *antiAll↑,
3787- H2,    Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis
- Review, AD, NA
*Inflam↓, *antiOx↑, *ROS↓, *other↝, *NF-kB↓, *IL2↓, *IL6↓, *TNF-α↓, *HO-1↑, Apoptosis↑, TumAuto↑, *Sepsis↓, *NLRP3↓, Pyro↑,
3766- H2,    The role of hydrogen in Alzheimer′s disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *AMPK↑, *SIRT1↑, *FOXO↑, *mtDam↓, *neuroP↑, *ROS↓, *p38↓, *cognitive↑, *BDNF↑, *memory↑, *lipid-P↓, *IL6↓, *TNF-α↓, *JNK↓, *NF-kB↓, *NLRP3↓,
3771- H2,    Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
- Review, AD, NA - Review, Stroke, NA
*cognitive↑, AntiCan↑, *Inflam↓, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *GPx↑, *MDA↑, *BBB↑, *OS↑, *Ca+2↓, *APP↓, *p‑tau↓,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
3765- H2,    Therapeutic Inhalation of Hydrogen Gas for Alzheimer’s Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study
- Study, AD, NA
*antiOx↑, *Inflam↓, *cognitive↑, *BBB↑,
3764- H2,    Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model
- in-vivo, AD, NA
*memory↑, *Aβ↓, *p‑tau↓, *BAX↓, *ROS↓, *NO↓, *Ca+2↓, *MDA↓, *Catalase↓, *GPx↓, *TNF-α↓, *Bcl-2↑, *VEGF↑, *Inflam↓, *cognitive↑,
3767- H2,    The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges
- Review, AD, NA
*Inflam↓, *neuroP↑, *toxicity↓, *antiOx↑, *ROS↓, *NLRP3↓, *IL1β↓, *mtDam↓, *ATP↑, *AMPK↑, *FOXO3↑, *SOD1↑, *Catalase↑, *NRF2↑, *NO↓, *MDA↓, *lipid-P↓, *memory↑, *ER(estro)↓, *BDNF↑, *cognitive↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *BP∅, *BBB↑,
3776- H2,    The role of hydrogen in Alzheimer's disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *NLRP3↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *ROS↓, *BDNF↑,
3775- H2,    Molecular hydrogen therapy for neurological diseases: a review of current evidence
- Review, AD, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑,
3774- H2,    The role of hydrogen in Alzheimer’s disease
- Review, AD, NA
*Inflam↓, *antiOx↑, *NLRP3↓, *memory↑, *Aβ↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *p‑p38↓, *JNK↓, *ROS↓, *cognitive↑, *ER(estro)↑, *BDNF↑,
3772- H2,    Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *Inflam↓, *ROS↓, *GutMicro↑, *TNF-α↓, *IL6↓, *IL1β↓, *IL10↓, *Catalase↑, *GSH↑,
3773- H2,    Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases
- Review, Park, NA
*neuroP↑, *antiOx↑, *Inflam↓, *ROS↓, *NADPH↓, *NRF2↑, *BBB↑, *IL1β↓, *IL6↓, *TNF-α↓, *NF-kB↓, *NLRP3↓, *Sepsis↓, *p‑mTOR↓, *AMPK↑, *SIRT1↑, *HO-1↑,
3761- H2,    Therapeutic Inhalation of Hydrogen Gas for Alzheimer's Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study
- Human, AD, NA
*cognitive↑, *BBB↑, *ROS↓, *NRF2↑, *Inflam↓, *NFAT↓, *FAO↓, *4-HNE↓, *PGC-1α↑, *Ferroptosis↓,
2513- H2,    Hydrogen therapy: from mechanism to cerebral diseases
- Review, Stroke, NA
*BBB?, *antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Dose↝,
2527- H2,    The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats
- in-vivo, Wounds, NA
*Dose↝, *SOD↑, *EGF↑, *antiOx↑, *Inflam↓, *Dose↝,
2525- H2,    Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis
- in-vivo, Var, NA
OS↓, cardioP↑, *AST↓, ALAT↓, *ROS↓, *MDA↓, *hepatoP↑, *Inflam↓, chemoP↑,
2523- H2,    Prospects of molecular hydrogen in cancer prevention and treatment
- Review, Var, NA
ROS↓, TumCP↓, TumMeta↓, AntiTum↑, GutMicro↑, Inflam↓, OS↑, radioP↑, selectivity↑, SOD↑, IL1β↑, IL8↑, TNF-α↑, neuroP↑,
2521- H2,    Oxyhydrogen Gas: A Promising Therapeutic Approach for Lung, Breast and Colorectal Cancer
- Review, CRC, NA - Review, Lung, NA - Review, BC, NA
Inflam↑, ROS↓, ChemoSen↑, p‑PI3K↓, p‑Akt↓, QoL↑, GutMicro↑, chemoP↑, radioP↑, *NRF2↑, *Catalase↑, *GPx↑, *HO-1↑, *SOD↑, *TNF-α↓, *IL4↓, *IL6↓, ChemoSen↑, Appetite↑, cognitive↑, Pain↓, Sleep↑, other?,
2516- H2,    Hydrogen Gas in Cancer Treatment
- Review, Var, NA
*Half-Life↓, *ROS↓, *selectivity↑, *SOD↑, *HO-1↑, *NRF2↑, *chemoP↑, *radioP↑, ROS↑, *Inflam↓, eff↑, *TNF-α↓, *IL6↓, *cl‑Casp8↑, *Bax:Bcl2↓, *Apoptosis↓, *cardioP↑, *hepatoP↑, *RenoP↑, *chemoP↑, eff↝, chemoP↑, radioP↑, Synergy↑, TumCG↓, Ki-67↓, VEGF↓, selectivity↑,
2515- H2,    Recent Advances in Studies of Molecular Hydrogen against Sepsis
- Review, Sepsis, NA
*Sepsis↓, *Inflam↓, *antiOx↑, *ROS↓, *NADPH↓,

Showing Research Papers: 601 to 650 of 1306
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1306

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 3,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 6,   antiOx↑, 37,   antiOx⇅, 2,   ARE↓, 1,   Catalase↓, 6,   Catalase↑, 6,   Fenton↑, 1,   frataxin↑, 1,   GCLC↑, 1,   GPx↑, 3,   GPx4↓, 5,   GSH↓, 28,   GSH↑, 7,   GSR↑, 1,   GSTs↑, 4,   GSTs↝, 1,   H2O2↓, 1,   H2O2↑, 4,   HO-1↓, 4,   HO-1↑, 18,   HO-2↓, 1,   Iron↑, 4,   Iron↝, 1,   lipid-P?, 1,   lipid-P↓, 5,   lipid-P↑, 12,   MDA↓, 5,   MDA↑, 10,   MPO↓, 5,   NADH↓, 2,   NOX↓, 1,   NOX4↑, 1,   NQO1↓, 1,   NQO1↑, 4,   NRF2↓, 16,   NRF2↑, 22,   Prx↓, 2,   Prx4↑, 1,   PrxII↓, 1,   PYCR1↓, 1,   ROS?, 1,   ROS↓, 36,   ROS↑, 218,   ROS⇅, 7,   ROS↝, 2,   i-ROS↓, 1,   i-ROS↑, 3,   mt-ROS↑, 5,   SOD?, 1,   SOD↓, 7,   SOD↑, 7,   SOD1↑, 1,   SOD2↓, 4,   SOD2↑, 1,   ac‑SOD2↓, 1,   Thiols↓, 2,   Trx↓, 2,   TrxR↓, 2,   TrxR1↓, 2,   xCT/SLC7A11↓, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

FTH1↓, 1,   IronCh↑, 4,   IronCh∅, 1,   Tf↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   CDC2↓, 2,   CDC25↓, 7,   compI↓, 2,   compII↓, 1,   compIII↓, 1,   compIV↓, 1,   EGF↓, 1,   ETC↓, 2,   HSP60/HSPD1↓, 1,   MFN2↑, 1,   mitResp↓, 1,   mitResp↑, 1,   MKK7↓, 1,   mtDam?, 1,   mtDam↓, 1,   mtDam↑, 23,   OCR↓, 2,   OXPHOS↓, 5,   OXPHOS↝, 1,   PDH↑, 1,   PGC-1α↑, 1,   PINK1↑, 1,   SDH↓, 1,   SIRT3↓, 2,   SIRT3↑, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   5-HETE↓, 1,   5LO↓, 6,   ACC↑, 1,   ACC1↓, 1,   Acetyl-CoA↓, 1,   ACLY↓, 2,   ACSL4↑, 1,   ALAT↓, 10,   AMPK↓, 1,   AMPK↑, 19,   AMPK↝, 1,   p‑AMT/GCST/T-protein↑, 1,   ATGL/PNPLA2↓, 1,   ATP↓, 20,   ATP↑, 1,   mt-ATP↓, 1,   BHB↑, 1,   Buty↑, 1,   CAIX/CA9↓, 3,   CRM↑, 2,   DHODH↓, 1,   ECAR↓, 1,   ECAR↝, 1,   ENO1↓, 1,   FAO↑, 1,   FASN↓, 8,   FFA/NEFA↓, 1,   G6PD↓, 1,   GLS↓, 1,   glucose↓, 2,   GlucoseCon↓, 9,   glut↓, 1,   GlutMet↓, 2,   Glycolysis↓, 32,   Glycolysis↝, 1,   GSK‐3β↓, 11,   GSK‐3β↑, 6,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 5,   HK2↓, 14,   HMG-CoA↓, 1,   HMGCS2↑, 1,   HSL/LIPE↓, 1,   p‑HSL/LIPE↑, 1,   lactateProd↓, 11,   lactateProd↑, 1,   LDHA↓, 6,   LDL↓, 1,   lipidLev↓, 1,   lipoGen↓, 1,   MCT4↓, 2,   NAD↓, 1,   NAD↑, 2,   NADPH↓, 3,   NADPH↑, 2,   PCK1↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 6,   PDK3↑, 1,   PFK↓, 2,   PKM2↓, 13,   PLA2↓, 1,   Pyruv↓, 1,   SCD1↓, 2,   SCFAs↑, 1,   SIRT1↓, 8,   SIRT1↑, 5,   SREBP1/SREBF1↓, 1,   SREBP2↓, 2,   TCA↓, 2,   Warburg↓, 10,  

Cell Death(tgid=5) ⓘ

AIF↑, 10,   APAF1↑, 9,   Apoptosis?, 4,   Apoptosis↓, 10,   Apoptosis↑, 233,   mt-Apoptosis↑, 1,   ASC↑, 1,   BAD↓, 1,   BAD↑, 7,   Bak↓, 1,   Bak↑, 8,   BAX↓, 4,   BAX↑, 96,   Bax:Bcl2↑, 19,   Bcl-2↓, 116,   Bcl-2↑, 3,   Bcl-xL↓, 24,   Bcl-xL↑, 1,   BID↑, 2,   p‑BID↓, 1,   cl‑BID↑, 1,   BIM↓, 1,   BIM↑, 3,   BNIP3↑, 1,   Casp↓, 1,   Casp↑, 39,   Casp↝, 1,   Casp1↓, 2,   Casp1↑, 2,   cl‑Casp1↓, 1,   Casp10↑, 1,   Casp12↑, 3,   Casp3↓, 7,   Casp3↑, 131,   cl‑Casp3↑, 19,   cl‑Casp3⇅, 1,   proCasp3↓, 1,   Casp6↓, 1,   Casp6↑, 1,   Casp7↑, 18,   cl‑Casp7↑, 5,   Casp8↓, 2,   Casp8↑, 37,   cl‑Casp8↑, 2,   proCasp8↑, 1,   Casp9↓, 2,   Casp9↑, 88,   cl‑Casp9↑, 9,   CellShr↑, 1,   cFLIP↓, 4,   Cyt‑c↓, 3,   Cyt‑c↑, 82,   Diablo↑, 5,   DR5↓, 1,   DR5↑, 15,   DR5↝, 1,   Endon↑, 1,   FADD↑, 3,   Fap1↓, 1,   Fas?, 1,   Fas↓, 2,   Fas↑, 14,   FasL↓, 1,   FasL↑, 4,   Ferroptosis↑, 8,   GranB/GZMB↓, 1,   GranB/GZMB↝, 1,   GSDMD↑, 1,   IAP1↓, 9,   IAP2/BIRC3↓, 4,   IAP2/BIRC3↑, 1,   cl‑IAP2/BIRC3↑, 1,   iNOS↓, 23,   iNOS↑, 1,   Mcl-1↓, 12,   Mcl-1↑, 1,   p‑Mcl-1↓, 1,   cl‑Mcl-1↑, 1,   MDM2↓, 8,   MDM2↑, 2,   p‑MDM2↓, 1,   MOMP↓, 1,   MOMP↑, 5,   Necroptosis↑, 2,   necrosis↑, 3,   NOXA↑, 3,   p38↓, 4,   p38↑, 17,   p‑p38↓, 4,   p‑p38↑, 4,   Paraptosis↑, 1,   Perforin↝, 1,   pS2/TFF1↓, 1,   PUMA↑, 4,   Pyro↑, 3,   survivin↓, 41,   TNFR 1↑, 1,   TRAIL↑, 3,   TRAIL⇅, 1,   TRAILR↑, 2,   TumCD↓, 2,   TumCD↑, 14,   XIAP↓, 26,   XIAP↑, 1,   YAP/TEAD↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 135,   Akt↑, 8,   p‑Akt↓, 31,   AKT1↓, 1,   Akt2↓, 1,   CaMKII ?, 1,   CIP2A↓, 1,   CK2↓, 6,   cMET↓, 1,   p‑cMET↑, 1,   CREB↓, 1,   cSrc↓, 2,   DDIT4↑, 1,   EF-1α↓, 1,   EGFR↓, 33,   EGFR↑, 1,   p‑EGFR↓, 1,   ERK↓, 47,   ERK↑, 5,   p‑ERK↓, 17,   p‑ERK↑, 1,   FGFR1↓, 1,   FOXD3↑, 1,   HCAR2↑, 4,   HER2/EBBR2↓, 11,   HGF/c-Met↓, 2,   Hippo↑, 1,   IGF-1R↓, 2,   IGF-1R↑, 1,   IGF-2R↑, 1,   IGFR↓, 1,   IKKα↓, 5,   IκB↓, 2,   JAK↓, 5,   JAK1↓, 3,   JAK1↑, 2,   JAK2↓, 18,   p‑JAK2↓, 1,   JAK3↓, 1,   JNK↓, 9,   JNK↑, 18,   p‑JNK↓, 3,   p‑JNK↑, 7,   LIMK1↓, 1,   MAPK↓, 36,   MAPK↑, 14,   MAPK↝, 1,   p‑MAPK↓, 1,   MARK4↓, 1,   MEK↓, 4,   MKK4↓, 1,   MKP1↝, 1,   mTOR↓, 75,   mTOR↝, 2,   p‑mTOR↓, 9,   mTORC2↓, 2,   OR13G1?, 1,   p70S6↓, 1,   P70S6K↓, 3,   P90RSK↓, 1,   PDE3B↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 114,   PI3K↑, 2,   p‑PI3K↓, 5,   PIK3CA↓, 1,   PKA↓, 2,   p‑PKA↓, 1,   PKCδ↓, 10,   PRKCQ/PKCθ↓, 1,   PTEN↓, 5,   PTEN↑, 28,   Raf↓, 4,   c-Raf↓, 1,   RAS↓, 10,   RAS↑, 1,   Rictor↓, 1,   RIP1↓, 1,   p‑S6K↓, 1,   SHP1↓, 1,   SHP1↑, 2,   Sp1/3/4↓, 12,   STAT↓, 7,   STAT3↓, 78,   STAT3↑, 4,   p‑STAT3↓, 8,   STAT4↓, 1,   STAT6↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF2↓, 1,   ATF4↑, 9,   ATF4↝, 1,   CBP↓, 2,   cJun↓, 5,   cJun↑, 1,   p‑cJun↓, 1,   p‑cJun↑, 1,   cMyc↓, 35,   cMyc↑, 1,   DNMT1↓, 7,   DNMT3A↓, 2,   DNMT3B↓, 3,   DNMTs↓, 7,   EZH2↓, 4,   FOXM1↓, 3,   FOXO1↓, 2,   FOXO1↑, 3,   FOXO3↓, 1,   FOXO3↑, 4,   FOXO3↝, 1,   FOXO4↓, 1,   FOXO4↑, 1,   H3↑, 1,   p‑H3↓, 1,   ac‑H3↓, 1,   ac‑H3↑, 1,   H4↑, 2,   ac‑H4↓, 1,   ac‑H4↑, 1,   HATs↓, 5,   HATs↑, 3,   HDAC↓, 22,   HDAC1↓, 7,   HDAC2↓, 5,   HDAC3↓, 5,   HDAC4↓, 1,   HDAC6↓, 2,   HDAC8↓, 3,   HES1↓, 2,   Matr↓, 1,   miR-106b↓, 2,   miR-124-3p↓, 1,   miR-143↑, 1,   miR-148a↑, 1,   miR-155↓, 1,   miR-19b↓, 2,   miR-200b↑, 2,   miR-200c↑, 1,   miR-203↑, 1,   miR-21↓, 5,   miR-218↑, 1,   miR-25-5p↓, 1,   miR-27a-3p↓, 2,   miR-34a↓, 2,   miR-34a↑, 6,   miR-590-3p↑, 1,   Myc↓, 5,   n-MYC↓, 1,   OCT4↓, 8,   other?, 1,   other↓, 5,   other↑, 10,   other⇅, 1,   other↝, 16,   PCAF↓, 2,   PhotoS↑, 3,   sonoS↑, 1,   SOX2↓, 6,   SOX4↓, 2,   SOX4↑, 1,   SOX9?, 1,   SUMO↓, 1,   TCF-4↓, 1,   tumCV?, 2,   tumCV↓, 59,   UTF1↑, 1,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 20,   cl‑CHOP/DDIT3↑, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↑, 6,   p‑eIF2α↓, 1,   p‑eIF2α↑, 1,   ER Stress↓, 1,   ER Stress↑, 37,   GRP78/BiP?, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 7,   GRP78/BiP↝, 1,   GRP94↑, 1,   HSP27↓, 5,   HSP70/HSPA5↓, 3,   HSP70/HSPA5↑, 5,   HSP72↓, 1,   HSP90↓, 8,   HSPs↓, 1,   HSPs↑, 1,   HTRA↓, 1,   IRE1↑, 2,   p‑IRE1↓, 1,   NQO2↑, 1,   PERK↑, 8,   p‑PERK↑, 1,   Proteasome↓, 1,   UPR↑, 7,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 7,   ATG7↑, 1,   Beclin-1/ATG6↓, 3,   Beclin-1/ATG6↑, 13,   CTSK↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↑, 1,   LC3B-II↑, 2,   LC3I↑, 1,   LC3II↓, 2,   LC3II↑, 14,   LC3s↑, 1,   MitoP↑, 1,   p62↓, 8,   p62↑, 3,   PARK2↑, 1,   SESN2↑, 2,   TumAuto↓, 1,   TumAuto↑, 47,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

8-oxo-dG↓, 1,   ATM↑, 4,   BRCA1↓, 2,   BRCA1↑, 1,   p‑BRCA1↑, 1,   BRCA2↓, 1,   DFF45↑, 1,   DNAdam↓, 6,   DNAdam↑, 55,   DNArepair↓, 3,   hTERT/TERT↓, 8,   MGMT↓, 1,   NHEJ↓, 1,   p16↑, 1,   P53↓, 3,   P53↑, 78,   P53↝, 2,   p‑P53↓, 1,   p‑P53↑, 2,   p53 Wildtype↑, 1,   p73↑, 1,   PARP↓, 3,   PARP↑, 14,   cl‑PARP↓, 2,   cl‑PARP↑, 51,   PARP1↑, 3,   cl‑PARP1↑, 2,   PCNA↓, 32,   POLD1↓, 1,   SIRT6↓, 1,   SIRT6↑, 1,   Telomerase↓, 11,   TOP1↓, 7,   TOP2↓, 5,   TOP2↑, 2,   TP53↓, 2,   TP53↑, 1,   γH2AX↑, 3,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 14,   CDK1↑, 3,   CDK2↓, 31,   CDK2↑, 2,   CDK4↓, 36,   CDK4↑, 1,   p‑CDK4↓, 1,   CDK6↓, 11,   CDK6↑, 1,   CDK7↓, 1,   CDK8↓, 2,   CHK1↓, 1,   CHK1↑, 1,   Chk2↑, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 7,   CycB/CCNB1↓, 19,   CycB/CCNB1↑, 3,   cycD1/CCND1↓, 75,   cycD1/CCND1↑, 2,   p‑cycD1/CCND1↓, 1,   CycD3↓, 1,   cycE/CCNE↓, 19,   E2Fs↓, 4,   GADD45A↓, 1,   Ki-67↓, 29,   Ki-67↑, 1,   mitA↑, 2,   P21?, 1,   P21↓, 7,   P21↑, 46,   p‑P21↑, 1,   p27/CDKN1B↓, 3,   p27/CDKN1B↑, 19,   pRB↓, 3,   p‑pRB↓, 3,   RB1↑, 2,   p‑RB1↓, 5,   Securin↓, 1,   TumCCA↓, 3,   TumCCA↑, 186,   WEE1↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   p‑4E-BP1↓, 1,   ALDH↓, 3,   ALDH1A1↓, 3,   BMP7/OP1↓, 1,   BMPs↑, 1,   CD133↓, 6,   CD24↓, 1,   CD34↓, 1,   cFos↓, 4,   CSCs?, 1,   CSCs↓, 32,   Diff↓, 2,   Diff↑, 6,   FGF↓, 1,   Gli↓, 2,   Gli1↓, 3,   HH↓, 4,   IGF-1?, 1,   IGF-1↓, 9,   IGF-2↓, 1,   IGFBP3↑, 2,   JAG1↓, 1,   Jun↓, 1,   Ki-67↓, 29,   Ki-67↑, 1,   Let-7↑, 2,   mTORC1↓, 6,   p‑mTORC1↓, 1,   Nanog↓, 5,   Nestin↓, 3,   NOTCH↓, 14,   NOTCH↑, 1,   NOTCH1↓, 12,   NOTCH1↑, 3,   NOTCH3↓, 2,   p300↓, 3,   PTCH1↓, 1,   SCF↓, 1,   Shh↓, 4,   Smo↓, 2,   STAT1↓, 2,   TumCG↓, 83,   TumCG↑, 4,   TumCP↓, 163,   TumCP↑, 3,   Wnt↓, 37,   Wnt↑, 2,   Wnt/(β-catenin)↓, 3,  

Migration(tgid=13) ⓘ

AntiAg?, 1,   AntiAg↓, 1,   AntiAg↑, 3,   AP-1↓, 9,   AP-1↑, 1,   ASAP2↓, 1,   AXL↓, 1,   BACH1↓, 1,   CA↓, 2,   Ca+2↓, 3,   Ca+2↑, 29,   Ca+2↝, 4,   i-Ca+2?, 1,   i-Ca+2↑, 1,   cal2↑, 1,   Cal9↑, 1,   CCN2/CTGF↓, 3,   Cdc42↓, 1,   Cofilin↓, 1,   p‑Cofilin↑, 1,   COL1↓, 2,   COL3A1↓, 1,   E-cadherin↓, 6,   E-cadherin↑, 32,   EMT↓, 65,   EMT↑, 2,   EMT↝, 1,   EpCAM↓, 2,   F-actin↓, 2,   FAK↓, 17,   FAK↑, 1,   p‑FAK↓, 5,   fascin↓, 1,   Fibronectin↓, 1,   GIT1↓, 1,   GLI2↓, 1,   ITGB1↓, 3,   ITGB3↓, 1,   ITGB4↓, 1,   KRAS↓, 1,   LAMs↓, 2,   LEF1↓, 2,   LIMK2↓, 1,   LRP1↑, 1,   MALAT1↓, 2,   MET↓, 1,   MET↑, 1,   p‑MET↓, 1,   MMP1↓, 6,   MMP13↓, 3,   MMP2↓, 74,   MMP2↑, 1,   MMP3↓, 4,   MMP7↓, 7,   MMP9↓, 93,   MMP9↑, 4,   MMPs↓, 36,   MUC4↓, 2,   N-cadherin↓, 19,   pax↓, 1,   PDGF↓, 6,   PGF↓, 1,   Rac1↓, 2,   RECK↑, 1,   Rho↓, 5,   ROCK1↓, 3,   Slug↓, 8,   Smad1↓, 1,   SMAD2↓, 1,   SMAD3↓, 2,   Snail↓, 13,   TET1↑, 3,   TGF-β↓, 18,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 8,   TIMP2↓, 1,   TIMP2↑, 7,   TIMP3↑, 1,   pol-TregCell↓, 1,   TRIB3↑, 3,   TSP-1↑, 2,   TumCA↓, 3,   TumCI↓, 98,   TumCMig↓, 90,   TumCMig↑, 1,   TumMeta↓, 86,   TumMeta↑, 7,   TumPF↓, 1,   Twist↓, 14,   TXNIP↑, 1,   uPA↓, 19,   uPAR↓, 1,   Vim?, 1,   Vim↓, 16,   Zeb1↓, 9,   Zeb1↑, 1,   ZEB2↓, 1,   α-SMA↓, 3,   α-SMA↑, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 50,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 125,   angioG↑, 2,   CCN1/CYR61↓, 1,   CD31/PECAM-1↓, 5,   Endoglin↑, 1,   eNOS↑, 1,   HIF-1↓, 7,   Hif1a↓, 44,   HIF2a↓, 1,   Hypoxia↓, 1,   LOX1↓, 3,   NO↓, 7,   NO↑, 3,   PGI2↓, 1,   PHDs↓, 1,   VCAM-1↓, 2,   VEGF↓, 100,   VEGF↑, 1,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 16,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   BBB↑, 7,   BBB∅, 1,   CellMemb↑, 1,   CLDN2↓, 1,   CX43/GJA1↓, 1,   EPR↑, 3,   GLUT1↓, 11,   GLUT4↓, 1,   IBI↑, 1,   MMP↓, 111,   MMP↑, 2,   MPT↑, 6,   NHE1↓, 2,   OATPs↓, 1,   TJ↓, 1,   TRPM7↓, 3,   TRPV1↓, 1,   TRPV1↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 3,   CCR7↓, 1,   CD25+↓, 1,   CD25+↑, 1,   CD4+↓, 2,   CD4+↑, 2,   CD44↓, 8,   CD47↓, 1,   CD59↑, 1,   CD8+↑, 4,   p‑cDC2↓, 1,   COX1↓, 7,   COX1↑, 1,   COX2/PTGS2↓, 113,   COX2/PTGS2↑, 2,   COX2/PTGS2↝, 1,   CXCc↓, 1,   CXCL12↓, 2,   CXCL16↓, 1,   CXCR4↓, 14,   DR4↑, 4,   Eos↑, 1,   FOXP3↑, 2,   FoxP3+↓, 1,   HCAR2↑, 4,   HLA-I/II↑, 1,   HMGB1↓, 5,   ICAM-1↓, 10,   IFN-γ↓, 8,   IFN-γ↑, 3,   IL1↓, 4,   IL1↑, 1,   IL10↓, 9,   IL10↑, 2,   IL12↑, 2,   IL17↓, 3,   IL17↑, 1,   IL18↓, 1,   IL18↑, 1,   IL1α↓, 1,   IL1β↓, 38,   IL1β↑, 3,   IL2↓, 5,   IL2↑, 3,   IL22↓, 1,   IL23↓, 1,   IL4↓, 3,   IL4↑, 1,   IL5↓, 1,   IL6↓, 61,   IL6↑, 2,   IL8↓, 11,   IL8↑, 1,   Imm↑, 29,   Imm↝, 6,   INF-γ↓, 1,   INF-γ↝, 1,   Inflam↓, 214,   Inflam↑, 3,   Inflam↝, 2,   LPS↓, 1,   LRIG1↑, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 9,   MCT1↓, 2,   MDSCs↓, 1,   MIP-1β↑, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 2,   MyD88↓, 1,   MyD88↑, 1,   Neut↑, 2,   NF-kB?, 1,   NF-kB↓, 170,   NF-kB↑, 6,   p‑NF-kB↓, 1,   p‑NF-kB↑, 2,   NK cell↑, 7,   NLRP3↓, 8,   NLRP3↑, 3,   NOD1↓, 1,   p65↓, 4,   p‑p65↓, 3,   PD-1↓, 3,   PD-L1↓, 9,   PGE2↓, 31,   PGE2↑, 1,   PSA↓, 12,   RAGE↓, 2,   RANTES↓, 1,   SOCS-3↓, 1,   T-Cell↑, 2,   TCF↓, 1,   Th1 response↑, 1,   TLR4↓, 10,   TLR4↑, 1,   TNF-α↓, 56,   TNF-α↑, 5,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   Treg lymp↓, 1,   TRIF↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,   GGT/CD224↓, 1,   pH↓, 1,   pH↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   AChE↓, 2,   ADAM10?, 1,   ADAM10↓, 1,   BChE↓, 1,  

Protein Aggregation(tgid=19) ⓘ

BACE/β-secretase↓, 1,   PSEN2/PS-2↓, 1,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ADRB2↓, 1,   AR↓, 10,   AR-V7?, 1,   CYP19?, 1,   ER(estro)↓, 1,   EstroRS/ERS↑, 1,   PPARα↓, 1,   PPARα↑, 1,   PPARγ↓, 4,   PPARγ↑, 8,   PPARγ↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 2,   BioAv↓, 55,   BioAv↑, 59,   BioAv⇅, 1,   BioAv↝, 15,   BioEnh↑, 2,   CBR1↓, 1,   ChemoSen↓, 1,   ChemoSen↑, 181,   ChemoSen⇅, 1,   ChemoSen↝, 1,   CompStab?, 1,   CompStab↑, 3,   CompStab↝, 3,   CYP1A1↓, 5,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP3A2↓, 1,   CYP3A4↓, 1,   DDS↑, 2,   Dose?, 5,   Dose↓, 3,   Dose↑, 10,   Dose⇅, 1,   Dose↝, 64,   Dose∅, 9,   DrugR↓, 1,   eff↓, 15,   eff↑, 87,   eff⇅, 1,   eff↝, 18,   eff∅, 4,   GSTM1↑, 1,   Half-Life↓, 15,   Half-Life↑, 2,   Half-Life↝, 16,   MDR1↓, 5,   MRP1/ABCC1↓, 3,   MRP1/ABCC1↝, 1,   NAT↓, 1,   P-gp/ABCB1↓, 16,   P-gp/ABCB1↑, 1,   P-gp/ABCB1⇅, 1,   P450↓, 2,   P450↝, 1,   RadioS↑, 53,   selectivity?, 1,   selectivity↓, 1,   selectivity↑, 90,   selectivity∅, 1,   Synergy↓, 1,   Synergy↑, 117,   Synergy↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP?, 1,   AFP↓, 3,   ALAT↓, 10,   ALB↑, 1,   ALP↓, 2,   AR↓, 10,   ascitic↓, 1,   AST?, 1,   AST↓, 7,   BloodF⇅, 1,   BP↓, 1,   BRCA1↓, 2,   BRCA1↑, 1,   p‑BRCA1↑, 1,   BUN↓, 1,   CA19-9↓, 1,   CEA↓, 2,   creat↓, 2,   CRP↓, 9,   DBIL↓, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 33,   EGFR↑, 1,   p‑EGFR↓, 1,   EstroRS/ERS↑, 1,   EZH2↓, 4,   FOXM1↓, 3,   HER2/EBBR2↓, 11,   hTERT/TERT↓, 8,   IBIL↓, 1,   IL6↓, 61,   IL6↑, 2,   KRAS↓, 1,   LDH↓, 7,   LDH↑, 2,   LDH↝, 1,   Maspin↑, 1,   Myc↓, 5,   NLR↓, 1,   NOS2↓, 1,   NOS2↑, 1,   PC↑, 1,   PD-L1↓, 9,   Polyps↓, 1,   PSA↓, 12,   RAGE↓, 2,   RBC↑, 1,   TBIL↓, 1,   TG/TAG↓, 1,   TP53↓, 2,   TP53↑, 1,   TRIB3↑, 3,   Tumccf↓, 2,   WBC↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiArt↑, 1,   AntiCan?, 1,   AntiCan↓, 5,   AntiCan↑, 121,   AntiCan⇅, 1,   AntiCan∅, 1,   antiD↑, 1,   AntiDiabetic↑, 3,   antiNeop↑, 5,   AntiTum↓, 1,   AntiTum↑, 53,   AntiTum∅, 1,   Appetite↑, 1,   cachexia↓, 1,   cardioP↑, 19,   CardioT↑, 2,   chemoP↑, 65,   chemoPv↑, 29,   ChemoSideEff↓, 4,   cognitive?, 1,   cognitive↑, 6,   DCR↑, 1,   fatigue↓, 2,   fatigue∅, 1,   hepatoP↓, 1,   hepatoP↑, 19,   hepatoP∅, 1,   memory↑, 4,   Mood↑, 1,   Mucositis↓, 1,   neuroP↑, 21,   NP/CIPN↓, 3,   Obesity↓, 2,   OS↓, 1,   OS↑, 19,   OS↝, 1,   OS∅, 2,   Pain↓, 6,   PFS↑, 1,   PFS∅, 1,   QoL↑, 8,   QoL∅, 1,   radioP↑, 23,   Remission↑, 1,   RenoP↑, 15,   Risk↓, 41,   Risk↑, 2,   Sleep↑, 2,   toxicity↓, 20,   toxicity↑, 5,   toxicity↝, 13,   toxicity∅, 3,   TumNum↓, 1,   TumVol↓, 16,   TumW↓, 7,   Weight↓, 1,   Weight↑, 3,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiViral↑, 2,   Bacteria↓, 5,   GutMicro↑, 18,   Sepsis↓, 4,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   Ingr?, 1,   Ingr↝, 9,  
Total Targets: 1058

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,   NA↑, 1,   NA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 4,   antiOx?, 2,   antiOx↓, 37,   antiOx↑, 535,   ARE↑, 7,   ARE↝, 1,   Bil↑, 2,   Catalase↓, 4,   Catalase↑, 152,   Copper↓, 1,   DPPH↓, 2,   DUOX1↓, 1,   Fenton↓, 5,   GCLC↑, 4,   GCLC↝, 1,   GCLM↑, 3,   GCLM↝, 1,   GPx↓, 2,   GPx↑, 112,   GPx1↑, 4,   GPx3↑, 1,   GPx4↓, 1,   GPx4↑, 6,   GSH↓, 4,   GSH↑, 162,   GSR↓, 2,   GSR↑, 24,   GSS↑, 1,   GSSG↓, 2,   GSTs↓, 4,   GSTs↑, 27,   H2O2↓, 8,   H2O2∅, 1,   HDL↓, 1,   HDL↑, 13,   HDL∅, 1,   HNE↓, 3,   HO-1?, 1,   HO-1↓, 4,   HO-1↑, 139,   HO-1⇅, 1,   HO-1↝, 1,   HO-2↓, 1,   hyperG↓, 3,   hyperG↝, 1,   Iron↓, 4,   Iron↑, 1,   Iron↝, 1,   Iron∅, 1,   Keap1↓, 8,   Keap1↑, 1,   Keap1↝, 2,   lipid-P?, 1,   lipid-P↓, 143,   lipid-P↑, 3,   mt-lipid-P↓, 1,   MDA↓, 139,   MDA↑, 4,   MPO↓, 28,   MPO↑, 1,   NADH↓, 1,   NFE2L2↓, 1,   NOX↓, 3,   NOX1↓, 1,   NOX2↓, 2,   NOX4↓, 9,   NQO1↑, 35,   NQO1↝, 2,   Nrf1↑, 2,   NRF2?, 1,   NRF2↓, 7,   NRF2↑, 236,   NRF2↝, 1,   NRF2∅, 1,   Prx↓, 1,   Prx↑, 2,   RNS↓, 8,   ROS?, 5,   ROS↓, 567,   ROS↑, 11,   ROS⇅, 4,   ROS↝, 1,   ROS∅, 1,   mt-ROS?, 1,   mt-ROS↓, 2,   SAM-e↑, 1,   selenoP↑, 10,   SOD↓, 6,   SOD↑, 210,   mt-SOD↑, 1,   SOD1↑, 9,   SOD2↓, 1,   SOD2↑, 9,   TAC↑, 24,   TBARS↓, 9,   Thiols↑, 2,   TOS↓, 2,   Trx↓, 1,   Trx↑, 6,   Trx1↑, 2,   TrxR↑, 1,   TrxR1↑, 1,   UCPs↑, 2,   uricA↓, 5,   VitC↑, 9,   VitE↓, 1,   VitE↑, 4,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   FTH1↑, 1,   IronCh↓, 1,   IronCh↑, 22,   IronCh↝, 1,   Mets↝, 1,   NCOA4↝, 1,   TfR1/CD71↓, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 2,   compII↑, 2,   compIII↑, 2,   compIV↑, 3,   DRP1/DNM1L↓, 1,   EGF↓, 1,   EGF↑, 1,   ETC↑, 3,   HSP60/HSPD1↓, 1,   Insulin↓, 4,   Insulin↑, 3,   MFN2↑, 2,   mitResp↑, 3,   mtDam↓, 10,   mtDam↑, 1,   OCR↓, 1,   OCR↑, 4,   OXPHOS↑, 1,   PDH↑, 1,   PGC-1α↓, 3,   PGC-1α↑, 10,   PGC-1α↝, 2,   PINK1↓, 1,   PINK1↑, 2,   SIRT3↑, 8,   TFAM↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12-HETE↓, 1,   12LOX↓, 2,   12LOX↑, 1,   5-HETE↓, 1,   5LO↓, 19,   5LO↝, 1,   ACC↓, 1,   ACC↑, 2,   Acetyl-CoA↓, 1,   Acetyl-CoA↑, 3,   ACSL4↓, 2,   adiP↓, 1,   adiP↑, 4,   ALAT?, 1,   ALAT↓, 55,   ALAT∅, 1,   AMPK↓, 2,   AMPK↑, 47,   p‑AMPK↑, 3,   ATP↓, 1,   ATP↑, 28,   ATP↝, 1,   BHB↑, 1,   Buty↑, 1,   cAMP↑, 6,   CPT1A↑, 1,   CRM↑, 3,   cytoP450↓, 1,   ECAR↓, 1,   Eic↓, 1,   FABP4↓, 1,   FAO↓, 1,   FAO↑, 3,   FASN↓, 3,   FFA/NEFA↓, 1,   G6PD↑, 1,   GAPDH↑, 1,   glucose↓, 18,   glucose↑, 2,   glucose↝, 4,   GlucoseCon↓, 1,   GlucoseCon↑, 11,   Glycolysis↓, 3,   Glycolysis↑, 1,   GSK‐3β↓, 25,   GSK‐3β↑, 2,   p‑GSK‐3β↓, 1,   p‑GSK‐3β↑, 4,   H2S↑, 2,   HK2↓, 2,   HMG-CoA↓, 3,   KeyT↝, 1,   lactateProd↓, 1,   LDHA↓, 2,   LDL↓, 43,   lipidLev↓, 7,   lipoGen↓, 1,   LTB4↓, 1,   LTC4↓, 1,   NAD↓, 1,   NAD↑, 3,   NAD↝, 1,   NADH:NAD↑, 1,   NADPH↓, 15,   NADPH↑, 10,   PDKs↓, 1,   PFK↓, 1,   PFK1↓, 1,   PFKP↓, 1,   PGC1A↑, 1,   PGM1?, 1,   PKM2↓, 8,   PLA2↓, 2,   PONs↓, 1,   PONs↑, 1,   SCFAs↑, 1,   SIRT1↓, 1,   SIRT1↑, 48,   SIRT1↝, 1,   SIRT2↑, 1,   SREBF2⇅, 1,   SREBP1/SREBF1↓, 1,   SREBP1/SREBF1↑, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 2,   APAF1↓, 1,   Apoptosis↓, 75,   Apoptosis↑, 2,   ASK1↓, 1,   BAD↓, 1,   BAX↓, 27,   BAX↑, 1,   Bax:Bcl2↓, 5,   Bcl-2↓, 5,   Bcl-2↑, 22,   Bcl-2↝, 1,   Bcl-xL↑, 1,   BNIP3↓, 1,   Casp↓, 4,   Casp1↓, 3,   Casp12↓, 2,   Casp3↓, 49,   Casp3↑, 3,   Casp3∅, 1,   cl‑Casp3↓, 6,   proCasp3↓, 1,   Casp6↓, 1,   Casp8↓, 2,   cl‑Casp8↓, 1,   cl‑Casp8↑, 1,   Casp9↓, 19,   Casp9↑, 2,   Cyt‑c↓, 8,   Cyt‑c↑, 1,   Cyt‑c∅, 2,   Fas↓, 2,   Ferroptosis↓, 14,   GranB/GZMB↓, 1,   GRP58↓, 1,   GSDMD?, 1,   GSDMD↓, 1,   iNOS↓, 88,   iNOS↑, 3,   necrosis↓, 3,   p38↓, 9,   p38↑, 1,   p‑p38↓, 7,   Pyro↓, 1,   survivin↓, 1,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 13,   Akt↑, 36,   Akt↝, 1,   p‑Akt↓, 6,   p‑Akt↑, 4,   AKT1↓, 1,   Akt2↓, 1,   AMPKα↑, 2,   CREB↓, 1,   CREB↑, 9,   p‑CREB↑, 3,   DYRK1A↓, 2,   EGFR↓, 1,   ERK↓, 14,   ERK↑, 14,   p‑ERK↓, 4,   p‑ERK↑, 3,   HCAR2↑, 1,   HER2/EBBR2↓, 1,   HGF/c-Met↑, 2,   IGF-1R↓, 1,   IKKα↓, 3,   IKKα↑, 1,   p‑IKKα↓, 1,   IκB?, 1,   JAK↓, 3,   JAK2↓, 3,   JAK2↑, 3,   JNK↓, 20,   JNK↑, 1,   p‑JNK↓, 7,   MAPK?, 1,   MAPK↓, 46,   MAPK↑, 5,   MAPK↝, 2,   p‑MAPK?, 1,   p‑MAPK↓, 2,   MEK↓, 1,   Mst1↓, 1,   mTOR↓, 14,   mTOR↑, 8,   mTOR↝, 1,   p‑mTOR↓, 5,   P70S6K↓, 1,   PDGFR-BB↓, 2,   PDGFR-BB↑, 1,   PDGFRB↓, 1,   PI3K↓, 12,   PI3K↑, 25,   PI3K↝, 1,   PKA↑, 3,   PKCδ↓, 4,   PKCδ↑, 6,   PP2A↑, 4,   PTEN↓, 5,   PTEN↑, 1,   PTP1B↓, 1,   RAS↓, 1,   RIP1↓, 1,   STAT↓, 4,   STAT3?, 1,   STAT3↓, 11,   STAT3↑, 5,   p‑STAT3↓, 1,   p‑STAT3↑, 1,   STAT4↓, 1,   STAT5↓, 1,   STEP↓, 1,   STK11/LKB1↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 14,   ATF2↑, 1,   ATF4↓, 4,   cJun↓, 2,   p‑cJun↓, 1,   cMyc↓, 1,   p‑cMyc↑, 1,   DNMT1↓, 2,   DNMT3A↓, 1,   DNMTs↓, 2,   FOXO↑, 3,   FOXO3↑, 6,   HATs↓, 2,   HDAC?, 1,   HDAC↓, 4,   HDAC↑, 2,   HDAC2↓, 2,   HOTAIR↑, 1,   KLF4↑, 1,   miR-155↓, 1,   miR-34a↓, 1,   OCT4↓, 1,   other?, 3,   other↓, 19,   other↑, 32,   other↝, 51,   other∅, 1,   SOX2↑, 1,   SOX9↑, 2,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   CHOP/DDIT3↓, 13,   CHOP/DDIT3↑, 1,   eIF2α↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 28,   ER Stress↑, 1,   GRP78/BiP↓, 11,   GRP78/BiP↑, 3,   GRP94↑, 1,   HSF1↑, 1,   HSP27↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 12,   HSP70/HSPA5↝, 1,   HSP90↓, 1,   HSP90↑, 2,   HSPs↓, 1,   HSPs↑, 2,   HSPs↝, 1,   IRE1↓, 3,   NQO2↑, 1,   PERK↓, 1,   p‑PERK↓, 1,   UPR↓, 1,   UPR↑, 2,   XBP-1↓, 3,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   ATG7↓, 1,   autophagy↓, 1,   autophagy↑, 1,   Beclin-1/ATG6↓, 3,   Beclin-1/ATG6↑, 8,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B↓, 1,   LC3B↑, 3,   LC3II↓, 2,   LC3II↑, 4,   MitoP↓, 1,   MitoP↑, 3,   p62↓, 3,   p62↑, 4,   PARK2↑, 4,   TFEB↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

8-oxo-dG↓, 1,   ATR↑, 1,   DNAdam↓, 30,   p16↓, 2,   P53↓, 6,   PARP↓, 2,   PARP1↓, 2,   cl‑PARP1↓, 1,   PCNA↓, 4,   SIRT6↑, 1,   Telomerase↓, 1,   TOP1↓, 1,   TP53↑, 1,   γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   CDK5↓, 2,   cellSen↓, 1,   cellSen↝, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   E2Fs↑, 1,   GADD34↓, 1,   Ki-67↓, 1,   Ki-67↑, 2,   P21↓, 3,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMPs↑, 1,   CEBPA↓, 1,   cFos↑, 1,   CHIP↑, 1,   Choline↑, 2,   Diff↑, 4,   Diff↝, 2,   EP2↓, 1,   FGF↑, 3,   GH↑, 1,   HH↓, 1,   IGF-1↓, 1,   IGF-1↑, 4,   IGFBP1↑, 1,   Jun↓, 1,   Ki-67↓, 1,   Ki-67↑, 2,   MSCs↑, 1,   mTORC1↓, 1,   Nestin↑, 1,   neuroG↑, 12,   NOTCH1↑, 1,   STAT1↓, 1,   TumCG↑, 1,   TumCP↓, 5,   tyrosinase↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 5,   AntiAg↑, 43,   AntiAg∅, 1,   AP-1↓, 11,   AP-1↑, 1,   ARG1/2↑, 1,   Ca+2?, 2,   Ca+2↓, 18,   Ca+2↑, 7,   Ca+2↝, 4,   cal2↓, 1,   Cartilage↑, 9,   COL1↓, 2,   COL1↑, 2,   COL2A1↑, 2,   COL3A1↓, 1,   E-cadherin↑, 2,   EMT↓, 2,   EMT↑, 1,   F-actin↑, 1,   FAK↑, 1,   Fibronectin↓, 1,   Fibronectin↑, 1,   Fibrosis↓, 1,   ITGA5↓, 1,   ITGB1↓, 1,   LRP1↑, 3,   MLC2/MYL9↝, 1,   MMP-10↓, 2,   MMP-10↝, 1,   MMP1↓, 1,   MMP13↓, 6,   MMP2↓, 7,   MMP2↑, 2,   MMP3↓, 3,   MMP3↑, 1,   MMP9↓, 21,   MMP9↑, 2,   MMPs↓, 3,   MMPs↑, 3,   MUC1↑, 4,   N-cadherin↑, 1,   Na+↑, 1,   NFAT↓, 1,   PDGF↓, 1,   PDGF↑, 1,   p‑Rac1↓, 1,   Rho↓, 3,   ROCK1↓, 4,   serineP↓, 1,   SLIT2↑, 1,   SMAD3↓, 1,   Snail↑, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 10,   TGF-β↑, 10,   TGF-β1↓, 4,   TGF-β1↑, 3,   TIMP1↓, 5,   TIMP1↑, 3,   TIMP2↑, 2,   TumCI↓, 2,   TumCMig↓, 1,   TumMeta↓, 1,   Twist↑, 1,   TXNIP↓, 6,   Tyro3↓, 1,   uPA↑, 1,   Vim↓, 2,   Vim↑, 1,   α-SMA↓, 6,   α-SMA↑, 1,   α-SMA↝, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↑, 2,   β-catenin/ZEB1↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 9,   angioG↑, 8,   angioG↝, 1,   CD31/PECAM-1↓, 1,   CD31/PECAM-1↑, 1,   E-sel↓, 5,   ECM/TCF↑, 1,   eNOS↓, 1,   eNOS↑, 4,   p‑eNOS↑, 1,   HIF-1↓, 1,   Hif1a↓, 8,   Hif1a↑, 3,   Hif1a↝, 1,   Hif1a∅, 1,   HIF2a↑, 1,   LOX1↓, 1,   NO?, 1,   NO↓, 67,   NO↑, 7,   P-sel↓, 1,   TXA2↓, 3,   VCAM-1↓, 19,   VEGF↓, 13,   VEGF↑, 11,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 2,   BBB↓, 8,   BBB↑, 80,   BBB↝, 6,   BBB∅, 3,   CLDN1↓, 2,   CLDN1↑, 3,   CLDN3↑, 1,   CLDN4↑, 1,   EPR↑, 2,   GastroP↑, 14,   GLUT1↑, 2,   GLUT2↑, 1,   GLUT3↑, 2,   GLUT4↑, 6,   H+/K+-ATPase↓, 1,   IBI↑, 12,   ketosis↑, 1,   memfluid↑, 2,   MMP↓, 2,   MMP↑, 30,   MMP∅, 2,   MUC19↓, 1,   MUC2↓, 1,   MUC2↑, 1,   MUC5AC↓, 2,   Na+↑, 1,   OATPs↓, 1,   OCLN↓, 2,   OCLN↑, 6,   OCLN↝, 1,   TJ↓, 1,   TJ↑, 6,   TRPA1↑, 2,   TRPC1↓, 1,   TRPM7↓, 1,   TRPV1↑, 5,   TRPV3↑, 2,   VGCC↓, 1,   VGSC↓, 1,   ZO-1↓, 2,   ZO-1↑, 9,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   BALF-Infl↓, 1,   BALF-Lym↓, 1,   CB2 / CNR2↑, 5,   CCL11↓, 1,   CD19↑, 1,   CD25+↑, 1,   CD4+↑, 5,   CD40↓, 1,   CD8+↑, 1,   cGAS–STING↓, 2,   COX1↓, 14,   COX1↑, 1,   COX2/PTGS2?, 1,   COX2/PTGS2↓, 144,   COX2/PTGS2↑, 2,   CXCc↓, 1,   CXCL1↓, 1,   CXCL15↓, 1,   CXCR2↓, 1,   CXCR3↓, 1,   CXCR4↓, 1,   Eos↓, 5,   FOXP3↑, 1,   GM-CSF↓, 1,   HCAR2↑, 1,   HMGB1↓, 9,   ICAM-1↓, 17,   IFN-γ↓, 21,   IFN-γ↑, 4,   IFN-γ∅, 1,   IgE↓, 4,   IgG1↓, 1,   IL1?, 1,   IL1↓, 11,   IL1↑, 1,   IL10?, 1,   IL10↓, 16,   IL10↑, 32,   IL12↓, 8,   IL13↓, 6,   IL17↓, 16,   IL17↑, 1,   IL18↓, 4,   IL1RL1/ST2↓, 1,   IL1α↓, 1,   IL1β↓, 164,   IL1β↑, 1,   IL2↓, 15,   IL2↑, 1,   IL22↓, 1,   IL23↓, 3,   IL33↓, 3,   IL4↓, 20,   IL4↑, 7,   IL5↓, 8,   IL5↑, 1,   IL6?, 3,   IL6↓, 197,   IL6↑, 4,   IL8?, 1,   IL8↓, 35,   IL8↑, 1,   ILC2↓, 1,   Imm↓, 1,   Imm↑, 48,   Imm↝, 4,   INF-γ↓, 3,   Inflam?, 6,   Inflam↓, 1076,   Inflam↑, 16,   Inflam∅, 2,   IP-10/CXCL-10↓, 2,   IRF3↓, 4,   LPS↓, 2,   LTA/TNF-β↓, 1,   LTA/TNF-β↑, 1,   M2 MC↑, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 21,   MCP1/CCL2↑, 2,   MCP1/CCL2↝, 1,   MIP‑1α/CCL3↓, 2,   MIP2↓, 3,   MyD88↓, 8,   NeuroI↓, 4,   Neut↓, 1,   Neut↑, 2,   NF-kB↓, 249,   NF-kB↑, 2,   p‑NF-kB↓, 4,   NK cell↑, 6,   NLRP3↓, 67,   NLRP3↑, 4,   p65↓, 6,   PAF↓, 2,   PAF↑, 1,   PGE1↓, 1,   PGE2↓, 52,   PGE2↑, 2,   PSA↓, 1,   PSA∅, 1,   RAGE↓, 5,   RANTES↓, 4,   Th1 response↓, 1,   Th17↓, 1,   Th2↓, 2,   TLR1↓, 3,   TLR2↓, 8,   TLR3↓, 1,   TLR4↓, 36,   TLR4↑, 1,   TLR4∅, 1,   TNF-α?, 1,   TNF-α↓, 269,   TNF-α↑, 4,   TRAF1↓, 1,   Treg lymp↑, 1,   Treg lymp↝, 1,   TRIF↓, 3,   VitD↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 3,   GGT/CD224↓, 1,   TREM2↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 2,   5HT↓, 1,   5HT↑, 16,   Ach↑, 25,   AChE↓, 98,   AChE↑, 1,   AChE∅, 2,   ADAM10↑, 6,   ADAM10↝, 1,   BChE↓, 24,   BChE∅, 1,   BDNF↓, 3,   BDNF↑, 71,   BDNF∅, 2,   proBDNF↑, 1,   BrainVol↑, 2,   ChAT↑, 13,   ChE↓, 1,   GABA↓, 3,   GABA↑, 9,   GABA↝, 1,   MAOA↓, 13,   MAOB↓, 4,   monoA↑, 1,   NGF↑, 9,   PSD95↑, 6,   SNAP25↑, 2,   SYP↑, 1,   TPH1↓, 1,   TrkB↑, 8,  

Protein Aggregation(tgid=19) ⓘ

AEP↓, 1,   AGEs↓, 12,   APOE4↓, 1,   APP↓, 15,   APP∅, 1,   cl‑APP↑, 1,   Aβ↓, 164,   Aβ↑, 2,   Aβ∅, 2,   Aβ42↓, 10,   BACE/β-secretase↓, 37,   BACE/β-secretase↑, 1,   IDE↑, 1,   NEP↑, 1,   PSEN1/PS1↑, 1,   tau↓, 37,   p‑tau↓, 49,   XO↓, 2,   XO↝, 1,   β-Amyloid↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   AhR↑, 2,   AR↓, 1,   BNP↓, 1,   cortisol↓, 1,   cortisol↑, 1,   CYP19↓, 1,   DHT↑, 1,   ER(estro)↓, 1,   ER(estro)↑, 2,   ERβ/ESR2↑, 1,   Estro↓, 1,   GLP-1R↑, 1,   GR↑, 1,   NR1H4↑, 1,   PPARα↑, 10,   PPARα↝, 1,   PPARγ↓, 5,   PPARγ↑, 24,   RAAS↓, 1,   SHBG↓, 1,   testos↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 84,   BioAv↑, 127,   BioAv⇅, 3,   BioAv↝, 74,   BioEnh↑, 12,   ChemoSen↑, 3,   CompStab↓, 2,   CompStab↑, 7,   CompStab↝, 3,   CYP2C19↓, 1,   CYP2C9↓, 1,   CYP2D6↓, 1,   CYP2E1↓, 1,   CYP3A4↓, 1,   DDS↑, 1,   Dose?, 10,   Dose↓, 3,   Dose↑, 9,   Dose↝, 148,   eff?, 1,   eff↓, 9,   eff↑, 88,   eff↝, 11,   GSTA1↑, 7,   Half-Life?, 1,   Half-Life↓, 18,   Half-Life↑, 9,   Half-Life↝, 31,   P-gp/ABCB1↓, 3,   P450↓, 3,   P450↑, 1,   RadioS↑, 1,   selectivity↑, 5,   Synergy↑, 50,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT?, 1,   ALAT↓, 55,   ALAT∅, 1,   ALB↑, 2,   ALB↝, 1,   ALP↓, 10,   anemia↓, 1,   AR↓, 1,   AST↓, 56,   AST∅, 1,   BG↓, 4,   Bil↑, 2,   BloodF↑, 13,   BMD↑, 8,   BP↓, 30,   BP↝, 1,   BP∅, 1,   BUN?, 1,   BUN↓, 6,   Calcium↑, 1,   Calcium↝, 2,   CEA↓, 1,   CK/CK-MB↓, 1,   colonLen↑, 2,   creat↓, 16,   CRP↓, 22,   EGFR↓, 1,   Ferritin↓, 1,   Ferritin↑, 1,   HbA1c↓, 1,   Hcy/homoC↓, 3,   Hcy/homoC↝, 1,   HemoG↑, 2,   HER2/EBBR2↓, 1,   HOMA↓, 1,   hs-CRP↓, 5,   IL6?, 3,   IL6↓, 197,   IL6↑, 4,   IRes↓, 1,   IRes↑, 1,   IRes↝, 1,   KeyT↝, 1,   LDH↓, 19,   LDH↑, 1,   Mag↑, 1,   NLR↓, 1,   NOS2↓, 5,   PSA↓, 1,   PSA∅, 1,   PV↓, 3,   RAGE↓, 5,   RBC↑, 1,   SpO2↑, 1,   TC↓, 5,   TG/TAG↓, 6,   TMAO↓, 1,   TMAO↑, 1,   TP53↑, 1,   UFR?, 1,   UFR↑, 2,   UR↓, 1,   Urea↓, 5,   VitD↑, 2,  

Functional Outcomes(tgid=23) ⓘ

Airway↓, 2,   AirwayM↓, 4,   Analgesic↑, 6,   AntiAge↑, 35,   antiAll?, 1,   antiAll↑, 47,   AntiArt↑, 18,   AntiCan?, 1,   AntiCan↓, 2,   AntiCan↑, 82,   antiCG↑, 2,   antiD↑, 1,   AntiDiabetic↓, 2,   AntiDiabetic↑, 93,   antiM↑, 1,   AntiMyl↑, 1,   antiNeop↑, 1,   antiPs↑, 3,   antiPy↑, 1,   AntiTum↓, 2,   AntiTum↑, 26,   ANXi↓, 1,   BOLD↑, 1,   Bone Healing↑, 1,   cachexia↓, 1,   cardioP?, 1,   cardioP↓, 3,   cardioP↑, 180,   cardioP⇅, 1,   cardioP∅, 1,   chemoP↑, 28,   chemoPv↑, 21,   ChemoSideEff↓, 1,   cognitive↓, 4,   cognitive↑, 221,   cognitive↝, 1,   cognitive∅, 1,   cough?, 1,   diuretic↑, 6,   fatigue↓, 3,   Hear↑, 1,   hepatoP↓, 5,   hepatoP↑, 164,   IPSS↝, 1,   Learn?, 1,   Learn↑, 16,   memory?, 1,   memory↑, 186,   memory∅, 1,   Mood↑, 13,   motorD↓, 1,   motorD↑, 24,   Mucositis↓, 2,   neuroP?, 3,   neuroP↓, 3,   neuroP↑, 405,   neuroP↝, 1,   NP/CIPN↓, 3,   Obesity↓, 39,   OS↑, 15,   Pain↓, 27,   PDE4↓, 1,   QoL↓, 1,   QoL↑, 9,   radioP↑, 16,   RenoP↑, 50,   Risk↓, 19,   Risk↑, 1,   Sleep↑, 8,   SoreThr?, 1,   Strength↓, 1,   Strength↑, 8,   Stress↓, 3,   Stroke↓, 31,   Tinn↓, 1,   toxicity?, 1,   toxicity↓, 93,   toxicity↑, 12,   toxicity⇅, 1,   toxicity↝, 22,   toxicity∅, 11,   Weight↓, 6,   Weight↑, 2,   Weight∅, 1,   Wound Healing↓, 1,   Wound Healing↑, 21,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiBio↑, 54,   AntiFungal↓, 2,   AntiFungal↑, 24,   AntiP↓, 1,   AntiP↑, 7,   AntiViral↑, 38,   Bacteria↓, 89,   Bacteria↑, 1,   Diar↓, 6,   Dysb↓, 1,   GutMicro↑, 93,   GutMicro↝, 2,   Inf↓, 3,   Sepsis↓, 20,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   CA↑, 1,   Catechins↑, 1,   FA↑, 1,   Fibre↑, 1,   Flav↑, 1,   GA↑, 1,   Ingr?, 2,   Ingr↑, 6,   Ingr↝, 35,   LT↑, 1,   Myr↑, 1,   Phen↑, 1,   Poly↑, 1,   QC↑, 2,  
Total Targets: 1030

Scientific Paper Hit Count for: Inflam, inflammation
43 Hydrogen Gas
41 Curcumin
34 Magnetic Fields
33 Thymoquinone
32 Quercetin
30 Silymarin (Milk Thistle) silibinin
24 Resveratrol
20 Lycopene
18 Alpha-Lipoic-Acid
18 Berberine
18 Selenium NanoParticles
18 Fisetin
18 Rosmarinic acid
16 Ashwagandha(Withaferin A)
16 Ferulic acid
16 Sulforaphane (mainly Broccoli)
15 Capsaicin
15 Carvacrol
15 Honokiol
15 Kaempferol
15 Luteolin
15 Urolithin
14 Propolis -bee glue
14 Emodin
14 Eugenol
14 Licochalcone A
13 Silver-NanoParticles
13 Apigenin (mainly Parsley)
13 Beta-Caryophyllene
12 Radiotherapy/Radiation
12 Baicalein
12 Chlorogenic acid
12 Chrysin
11 Cinnamon
11 Isoliquiritigenin
10 Crocetin
10 Chemotherapy
10 Dandelion Root
10 EGCG (Epigallocatechin Gallate)
10 Matrine
10 Pterostilbene
9 Selenite (Sodium)
9 Isovitexin
9 Boron
9 Ginger/6-Shogaol/Gingerol
9 Magnolol
9 Morin
8 Astaxanthin
8 Boswellia (frankincense)
8 α-Bisabolol / Chamomile oil
8 Rutin
8 Diclofenac
8 Fucoidan
8 Licorice
8 Piperlongumine
8 Vitamin C (Ascorbic Acid)
8 Shikonin
7 Allicin (mainly Garlic)
7 Betulinic acid
7 Vitamin B3,Niacin
7 Cisplatin
7 Butyrate
7 Centella asiatica / Gotu kola → asiaticoside
7 D-limonene
7 Gallic acid
7 Hyperoside
7 Moringa oleifera
7 Mushroom Lion’s Mane, Hericium erinaceus
7 Piperine
6 1,8-Cineole
6 Artemisinin
6 Aspirin
6 Caffeic acid
6 Thymol-Thymus vulgaris
6 Hydroxycinnamic-acid
6 Flaxseed/Linseed
6 Garcinol
6 HydroxyTyrosol
6 isoorientin
6 Vitexin
6 L-Theanine
6 Methylsulfonylmethane
5 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
5 Melatonin
5 Folic Acid, Vit B9
5 Phenethyl isothiocyanate
5 doxorubicin
5 Caffeic Acid Phenethyl Ester (CAPE)
5 Celastrol
5 chitosan
5 Chocolate
5 Coenzyme Q10
5 Ellagic acid
5 Shilajit/Fulvic Acid
5 isoquercitrin
5 Mung Bean Sprouts
5 Lactoferrin/Talactoferrin
5 Magnetic Field Rotating
5 Phycocyanin
5 Ursolic acid
4 Isothiocyanates
4 Bacopa monnieri
4 Cichoric acid / Chicoric acid
4 Carvone
4 Ginkgo biloba-EGb 761
4 Formononetin
4 SDG/lignans
4 Ginkgo biloba
4 Geraniol
4 Ginkgetin
4 Isobavachalcone
4 Isorhamnetin
4 Lemongrass Extract/Citral
4 Methylene blue
4 nicotinamide adenine dinucleotide
4 Nimbolide
4 Patchouli Oil (Pogostemon cablin)
4 Taurine
4 Vitamin B5,Pantothenic Acid
4 Vitamin D3
4 Vitamin K2
3 Anethole/trans-Anethole
3 Baicalin
3 Biochanin A
3 Vitamin B12
3 Benzyl isothiocyanate
3 Bromelain
3 Black Rice, Oryza sativa
3 Lecithin
3 Carnosine
3 Camu camu
3 Chyawanprash
3 methotrexate
3 Spermidine
3 Cucurbitacin
3 Date Fruit Extract
3 Docosahexaenoic Acid
3 eicosapentaenoic acid
3 diet Fermented Foods
3 Exercise
3 Gamma-aminobutyric acid
3 Genistein (soy isoflavone)
3 HydroxyCitric Acid
3 Inositol
3 phytic acid, Inositol hexakisphosphate
3 Linalool
3 5-fluorouracil
3 Mangiferin
3 Marjoram (Origanum majorana)
3 Purple Corn / Purple Maize
3 α-Santalol/Sandalwood oil
3 Sulfasalazine
3 Sesamin
3 Vitamin B1/Thiamine
2 Anthocyanins
2 alpha Linolenic acid
2 Fennel Oil/Foeniculum vulgare
2 Allyl isothiocyanate
2 brusatol
2 borneol
2 buckwheat sprouts
2 Paclitaxel/Taxol
2 Cat’s Claw
2 Celecoxib
2 Chlorophyllin
2 Choline
2 Selenium
2 Vitamin E
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Galantamine
2 Huperzine A/Huperzia serrata
2 diet Short Term Fasting
2 Indole-3-carbinol
2 Dipyridamole
2 Echinacea
2 Eurycomanone
2 flavonoids
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Ginkgolide B
2 Ginseng
2 Grapeseed extract
2 hydrogen sulfide
2 Orlistat
2 Hibiscus sabdariffa
2 Oleuropein
2 iodine
2 Inulin Prebiotic
2 isoflavones
2 Ivermectin
2 Juglone
2 Potassium
2 probiotics
2 Lutein
2 MBE, Maqui berry
2 Methyl salicylate / Sweet Birch oil
2 Metformin
2 Magnesium
2 Lemon Balm/Melissa officinalis
2 Naringin
2 Oleocanthal
2 Phenylbutyrate
2 Phosphatidylserine
2 Salvia officinalis
2 Shankhpushpi
2 Salvia miltiorrhiza
2 Terpinen-4-ol / Tea Tree Oil
2 Aflavin-3,3′-digallate
2 Turmerones
2 Zyflamend
1 2-DeoxyGlucose
1 5-Hydroxytryptophan
1 Annona atemoya Seed Extract
1 Açaí, Euterpe oleracea
1 Astragalus
1 Acetyl-l-carnitine
1 Aloe anthraquinones
1 beta-glucans
1 xanthohumol
1 Cannabidiol
1 beta-carotene(VitA)
1 Vitamin B6,pyridoxine
1 Bifidobacterium
1 Brucea javanica
1 Beetroot
1 Bruteridin(bergamot juice)
1 Black Seed Oil/Nigella sativa
1 Carnosic acid
1 Castalagin
1 Cannabichromene
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chaetocin
1 Prebiotic
1 Carica papaya leaf extract
1 Calorie Restriction Mimetics
1 Copper and Cu NanoParticles
1 Rivastigmine
1 Chlorella (Chlorella vulgaris)
1 Cynaropicrin
1 Deguelin
1 Dihydrocaffeic Acid
1 diet Ketogenic
1 Diindolylmethane
1 Disulfiram
1 immunotherapy
1 Electrical Pulses
1 Evodiamine
1 Ascorbyl Palmitate
1 Flickering Light Stimulation
1 Iron
1 Galloflavin
1 Gambogic Acid
1 Ginkgolic acids
1 Bifidobacterium animalis subsp. lactis GCL2505
1 γ-linolenic acid (Borage Oil)
1 Gossypol/AT-101
1 Graviola
1 Germacranolide sesquiterpene lactone
1 Siegesbeckia glabrescens
1 Helleborus niger extracts – Christmas Rose
1 Hops (Humulus lupulus)
1 Butein
1 Scopoletin
1 Lactobacillus
1 Zeaxanthin
1 Modified Citrus Pectin
1 irinotecan
1 MCT oil
1 Moringin
1 Mucuna pruriens/Velvet Bean
1 Mushroom Chaga, Inonotus obliquus
1 Nasturtium, Indian Cress
1 Neem
1 Oregano
1 Peppermint
1 Propyl gallate
1 Phenolic Acids
1 Propranolol
1 Psoralidin
1 Parthenolide
1 Pumpkin Seed Oil / Cucurbita pepo
1 Tamsulosin
1 EMF
1 Radio Frequency
1 Aromatherapy
1 Gold NanoParticles
1 Sesame seeds and Oil
1 Silicic Acid
1 Spirulina(Arthrospira/Limnospira)
1 cetuximab
1 Terminalia bellirica
1 Terpenoids
1 Thyme
1 Vitamin A, Retinoic Acid
1 Vitamin B2,Riboflavin
1 Walnut
1 Zinc
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:953  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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