eff Cancer Research Results

eff, efficacy: Click to Expand ⟱

Source:

Type:

Power to enhance an anti cancer effect

Scientific Papers found: Click to Expand⟱

3220-

EGCG,

Dual Roles of Nrf2 in Cancer

-

in-vitro,

Lung,

A549

NRF2↑, eff↓,

3241-

EGCG,

Epigallocatechin gallate triggers apoptosis by suppressing de novo lipogenesis in colorectal carcinoma cells

-

in-vitro,

CRC,

HCT116

0.5 ± 0.05 mm

-

in-vitro,

CRC,

HT29

0.8 ± 0.06 mm

-

in-vitro,

Liver,

HepG2

 > 1 mm

-

in-vitro,

Liver,

HUH7

 > 1 mm

tumCV↓, mtDam↑, Apoptosis↑, ATP↓, lipoGen↓, eff↑,

3215-

EGCG,

Epigallocatechin gallate modulates ferroptosis through downregulation of tsRNA-13502 in non-small cell lung cancer

-

in-vitro,

NSCLC,

A549

 111.1 μM

-

in-vitro,

NSCLC,

H1299

 5.564 μM

TumCP↓, Ki-67↓, GPx4↓, ACSL4↑, Iron↑, MDA↑, ROS↑, Ferroptosis↑, eff↑, NRF2↑, HO-1↑,

3202-

EGCG,

Epigallocatechin-3-gallate enhances ER stress-induced cancer cell apoptosis by directly targeting PARP16 activity

-

in-vitro,

Cerv,

HeLa

100uM

-

in-vitro,

HCC,

QGY-7703

PARP16↓, p‑PERK↓, Apoptosis↑, eIF2α↓, UPR↓, ER Stress↑, eff↑, GRP78/BiP↓,

3205-

EGCG,

The Role of Epigallocatechin-3-Gallate in Autophagy and Endoplasmic Reticulum Stress (ERS)-Induced Apoptosis of Human Diseas

-

Review,

Var,

NA

-

Review,

AD,

NA

Beclin-1↑, ROS↑, Apoptosis↑, ER Stress↑, *Inflam↓, *cardioP↑, *antiOx↑, *LDL↓, *NF-kB↓, *MPO↓, *glucose↓, *ROS↓, ATG5↑, LC3B↑, MMP↑, lactateProd↓, VEGF↓, Zeb1↑, Wnt↑, IGF-1R↑, Fas↑, Bak↑, BAD↑, TP53↓, Myc↓, Casp8↓, LC3II↑, NOTCH3↓, eff↑, p‑Akt↓, PARP↑, *Cyt‑c↓, *BAX↓, *memory↑, *neuroP↑, *Ca+2?, GRP78/BiP↑, CHOP↑, ATF4↑, Casp3↑, Casp8↑, UPR↑,

3212-

EGCG,

EGCG maintained Nrf2-mediated redox homeostasis and minimized etoposide resistance in lung cancer cells

-

in-vitro,

Lung,

A549

-

in-vivo,

Lung,

NCIH23

NRF2⇅, eff↑, SOD1↑, SOD1↓, MMP2⇅, MMP9⇅,

1514-

EGCG,

Preferential inhibition by (-)-epigallocatechin-3-gallate of the cell surface NADH oxidase and growth of transformed cells in culture

-

in-vitro,

Cerv,

HeLa

1-50uM

-

in-vitro,

Nor,

MCF10

selectivity↑, *toxicity∅, TumCG↓, NADHdeh?, eff↑, ENOX2↓, Dose?,

1503-

EGCG,

Epigenetic targets of bioactive dietary components for cancer prevention and therapy

-

Review,

NA,

NA

IC50 values ranging from 0.21 to 0.47 μM

selectivity↑, DNMT1↓, RECK↑, MMPs↓, TumCI↓, angioG↓, TumMeta↓, HATs↓, IκB↑, NF-kB↓, IL6↓, COX2↓, NOS2↓, ac‑H3↑, ac‑H4↑, eff↑,

1516-

EGCG,

Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential

-

Review,

NA,

NA

*Dose∅, Half-Life∅, BioAv∅, BBB↑, toxicity∅, eff↓, Apoptosis↑, Casp3↑, Cyt‑c↑, cl‑PARP↑, DNMTs↓, Telomerase↓, angioG↓, Hif1a↓, NF-kB↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, IGF-1↓, H3↓, HDAC1↓, *LDH↓, *ROS↓,

1515-

EGCG,

Phen,

Reciprocal Relationship Between Cytosolic NADH and ENOX2 Inhibition Triggers Sphingolipid-Induced Apoptosis in HeLa Cells

-

in-vitro,

Cerv,

HeLa

0.003 uM

-

in-vitro,

Nor,

MCF10

exceeded 20 uM

 note IC50 not reached for normal cells

-

in-vitro,

BC,

BT20

0.01 uM

selectivity↑, ENOX2↓, NADH↑, SK↓, eff↑, aSmase↑,

2309-

EGCG,

Chemo,

Targeting Glycolysis with Epigallocatechin-3-Gallate Enhances the Efficacy of Chemotherapeutics in Pancreatic Cancer Cells and Xenografts

-

in-vitro,

PC,

MIA PaCa-2

(20–100 μM) for 72 h

-

in-vitro,

Nor,

HPNE

-

in-vitro,

PC,

PANC1

-

in-vivo,

NA,

NA

mice

TumCG↓, eff↑, ROS↑, ECAR↓, ChemoSen↑, selectivity↑, Glycolysis↓, PFK↓, PKA↓, HK2∅, LDHA∅, PFKP↓, PKM2↓, H2O2↑, TumW↓,

2501-

EGCG,

A Case of Complete and Durable Molecular Remission of Chronic Lymphocytic Leukemia Following Treatment with Epigallocatechin-3-gallate, an Extract of Green Tea

-

Case Report,

AML,

NA

OS↑, Remission↑, eff↑, Dose↝,

2563-

EGCG,

Cardioprotective effect of epigallocatechin gallate in myocardial ischemia/reperfusion injury and myocardial infarction: a meta-analysis in preclinical animal studies

-

Review,

NA,

NA

cardioP↑, ROS↑, AntiAg↑, eff↑, COX1↓,

2561-

EGCG,

ASA,

Anti-platelet effects of epigallocatechin-3-gallate in addition to the concomitant aspirin, clopidogrel or ticagrelor treatment

-

ex-vivo,

Nor,

NA

40 participants

AntiAg↑, eff↑, Half-Life↝, other∅,

5931-

EGCG,

BTZ,

EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism

-

in-vitro,

Pca,

PC3

TumAuto↑, CHOP↓, TumCD↓, eff↓,

1322-

EMD,

The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers

-

Review,

Var,

NA

7.22 μg/mL

Apoptosis↑, TumCP↓, ROS↑, TumAuto↑, EMT↓, TGF-β↓, DNAdam↑, ER Stress↑, TumCCA↑, ATP↓, NF-kB↓, CYP1A1↑, STAC2↓, JAK↓, PI3K↓, Akt↓, MAPK↓, FASN↓, HER2/EBBR2↓, ChemoSen↑, eff↑, ChemoSen↑, angioG↓, VEGF↓, MMP2↓, eNOS↓, FOXD3↑, MMP9↓, TIMP1↑,

1329-

EMD,

Aloe-emodin induces cell death through S-phase arrest and caspase-dependent pathways in human tongue squamous cancer SCC-4 cells

-

in-vitro,

Tong,

SCC4

30 microM

TumCCA↑, eff↓, P53↑, P21↑, p27↑, cycA1/CCNA1↓, cycE/CCNE↓, TS↓, CDC25↓, AIF↑, proCasp9↓, Cyt‑c↑, MMP↓, Bax:Bcl2↑, Casp3↑, Casp9↑,

5530-

EP,

Expression of voltage-gated calcium channels augments cell susceptibility to membrane disruption by nanosecond pulsed electric field

-

in-vitro,

Nor,

HEK293

*CellMemb↑, *VGCC↑, *Ca+2↑, *MMP↓, *VGCC⇅, eff↑,

5487-

EP,

High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas

-

in-vivo,

GBM,

NA

Fischer rats

OS↑, CellMemb↑, Imm↑, Inflam↓, necrosis↑, Pyro↑, eff↑, IL2↑, IL6↑, IL17↑, IFN-γ↓,

5488-

EP,

An in vivo study of a custom-made high-frequency irreversible electroporation generator on different tissues for clinically relevant ablation zones

-

in-vivo,

Nor,

NA

18 New Zealand white rabbits

*MusCon↓, *Dose↓, *eff↑, *Temp↝,

5489-

EP,

Electroporation and cell killing by milli- to nanosecond pulses and avoiding neuromuscular stimulation in cancer ablation

-

in-vitro,

Colon,

NA

We measured electroporation and cell killing thresholds for 150 ns–1 ms PEF, uni- and bipolar, delivered in 10- to 300-pulse trains at up to 1 MHz rates.

eff↑, TumCD↑, MusCon↓, Temp↓, eff↑, eff↓, eff↑, eff∅, other↑,

5491-

EP,

Nano-pulse stimulation™ therapy (NPS™) is superior to cryoablation in clearing murine melanoma tumors

-

in-vivo,

Melanoma,

B16-F10

murine melanoma tumors, Mice: Female C57BL/6J mice, 6-8 weeks old

TumCD↑, eff↑, MusCon↓, CellMemb↑, ER Stress↑, other↝,

5492-

EP,

Nano-Pulse Stimulation Therapy in Oncology

-

in-vivo,

PC,

Panc02

tumor cells are injected intradermally so that they grow within the mouse skin.

-

in-vivo,

BC,

4T1

CellMemb↑, Ca+2↑, DNAdam↑, eff↝, Imm↑,

5519-

EP,

Nanosecond Pulsed Electric Fields (nsPEFs) for Precision Intracellular Oncotherapy: Recent Advances and Emerging Directions

-

Review,

Var,

NA

MMP↓, Ca+2↑, eff↑, ER Stress↑, selectivity↑, CSCs↓, CD44↓, CD133↓, ROS↑, Imm↑, DNAdam↑, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp9↑, TumCD↑, Fas↑, UPR↑, Dose↝, Dose↝, Dose↓, Dose↑, HMGB1↓, eff↑, EPR↑, ChemoSen↑, ETC↝, *AntiAge↑, *Hif1a↑, *SIRT1↑,

5047-

erastin,

The ferroptosis inducer erastin irreversibly inhibits system xc− and synergizes with cisplatin to increase cisplatin’s cytotoxicity in cancer cells

-

in-vitro,

Ovarian,

NA

xCT↓, GSH↓, Ferroptosis↑, ChemoSen↑, eff↑,

2204-

erastin,

Regulation of ferroptotic cancer cell death by GPX4

-

in-vitro,

fibroS,

HT1080

GSH↓, Ferroptosis↑, ROS↑, GPx↓, GPx4↓, lipid-P↑, eff↓, eff↑,

2144-

Ex,

Physical activity, hormone replacement therapy and breast cancer risk: A meta-analysis of prospective studies

-

Analysis,

NA,

NA

Risk↓, Dose?, eff↑,

2145-

Ex,

Leisure time physical activity and cancer risk: evaluation of the WHO's recommendation based on 126 high-quality epidemiological studies

-

Analysis,

Var,

NA

Risk↓, Dose↝, eff↑,

2146-

Ex,

A systematic review and meta-analysis of physical activity and endometrial cancer risk

-

Review,

Endo,

NA

Risk↓, eff↑,

2153-

Ex,

The Impact of Exercise on Cancer Mortality, Recurrence, and Treatment-Related Adverse Effects

-

Review,

Var,

NA

eff↑, BMD↑, cognitive↑, OS↑, Remission↑, eff↑,

2151-

Ex,

The effects of physical activity on overall survival among advanced cancer patients: a systematic review and meta-analysis

-

Review,

Var,

NA

eff↑, eff↝,

2150-

Ex,

Roles and molecular mechanisms of physical exercise in cancer prevention and treatment

-

Review,

Var,

NA

eff↓, Dose↝, TumCP↓, Apoptosis↓, ChemoSen↑, chemoP↑,

2149-

Ex,

Physical activity and exercise training in cancer patients

-

Analysis,

Var,

NA

eff↑, Dose↑,

4139-

Ex,

Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases

-

Review,

AD,

NA

*BDNF↑, *eff↑, *eff↑, *cognitive↑, *memory↑, *BrainVol↑, *TrkB↑, *GABA↑,

4141-

Ex,

Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis

-

Review,

AD,

NA

*BDNF↑, *other↑, *eff↑,

4143-

Ex,

Brain-Derived Neurotrophic Factor: A Connecting Link Between Nutrition, Lifestyle, and Alzheimer’s Disease

-

Review,

AD,

NA

*BDNF↑, *eff↑, *other↓, *eff↑,

4145-

Ex,

Effects of different physical activities on brain-derived neurotrophic factor: A systematic review and bayesian network meta-analysis

-

Review,

AD,

NA

*BDNF↑, *eff↑,

5061-

Ex,

Role of physical exercise in modulating the insulin-like growth factor system for improving breast cancer outcomes: A meta-analysis

-

Review,

BC,

NA

IGF-2↓, IGFBP1↓, HOMA↓, glucose∅, IGF-1∅, eff↑,

5235-

Ex,

Effect of Low-Intensity Aerobic Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Proteins in Healthy Men

-

Trial,

Nor,

NA

 Fourteen healthy men participated in cycle ergometer training at lactate threshold intensity for 60 min/day, 5 days/week for 6 weeks.

Insulin↓, IGF-1↓, IGFBP1↑, eff↑,

1622-

FA,

Folate and Its Impact on Cancer Risk

-

Review,

NA,

NA

eff↓,

1654-

FA,

Molecular mechanism of ferulic acid and its derivatives in tumor progression

-

Review,

Var,

NA

AntiCan↑, Inflam↓, RadioS↑, ROS↑, Apoptosis↑, TumCCA↑, TumCMig↑, TumCI↓, angioG↓, ChemoSen↑, ChemoSideEff↓, P53↑, cycD1/CCND1↓, CDK4↓, CDK6↓, TumW↓, miR-34a↑, Bcl-2↓, Casp3↑, BAX↑, β-catenin/ZEB1↓, cMyc↓, Bax:Bcl2↑, SOD↓, GSH↓, LDH↓, ERK↑, eff↑, JAK2↓, STAT6↓, NF-kB↓, PYCR1↓, PI3K↓, Akt↓, mTOR↓, Ki-67↓, VEGF↓, FGFR1↓, EMT↓, CAIX↓, LC3II↑, p62↑, PKM2↓, Glycolysis↓, *BioAv↓,

2173-

FA,

VitB12,

Elevated serum homocysteine levels associated with poor recurrence-free and overall survival in patients with colorectal cancer

-

Study,

CRC,

NA

Risk↓, eff↝, eff↝, homoC↓,

2174-

FA,

VitB12,

-

Analysis,

Var,

NA

homoC↓, eff↑, eff↑, eff↑, eff↝, homoC↝, other?,

2176-

FA,

VitB12,

Hyperhomocysteinemia and Cancer: The Role of Natural Products and Nutritional Interventions

-

Review,

Var,

NA

homoC↓, eff↝,

4069-

FA,

Folate, folic acid and 5-methyltetrahydrofolate are not the same thing

-

Review,

AD,

NA

*other↑, *BioAv↝, *other↝, *eff↑,

2499-

Fenb,

VitE,

Effects of fenbendazole and vitamin E succinate on the growth and survival of prostate cancer cells

-

in-vitro,

Pca,

PC3

TumCP∅, TumCP↓, toxicity↓, eff↑,

2498-

Fenb,

Unexpected Antitumorigenic Effect of Fenbendazole when Combined with Supplementary Vitamins

-

in-vivo,

lymphoma,

NA

mice

eff↓, eff↑, TumVol↓, antiOx↑, Hif1a↓,

2496-

Fenb,

Impairment of the Ubiquitin-Proteasome Pathway by Methyl N-(6-Phenylsulfanyl-1H-benzimidazol-2-yl)carbamate Leads to a Potent Cytotoxic Effect in Tumor Cells

-

in-vitro,

NSCLC,

A549

1.6 μm

-

in-vitro,

NSCLC,

H460

1.2 uM

TumCG↓, selectivity↑, P53↑, IKKα↑, ER Stress↑, GRP78/BiP↑, CHOP↑, ATF3↑, IRE1↑, NOXA↑, ROS↑, MMP↓, Cyt‑c↑, selectivity↑, eff↝,

2494-

Fenb,

Oral Fenbendazole for Cancer Therapy in Humans and Animals

-

Review,

Var,

NA

Glycolysis↓, GlucoseCon↓, ROS↑, Apoptosis↑, BioAv↓, eff↑, toxicity↓, BioAv↑, BioAv↑, hepatoP↓, eff↑,

2495-

Fenb,

Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells

-

in-vitro,

Melanoma,

A375

FBZ (1 and 2 μM)

P53↑, P21↑, TumCCA↑, MDM2↓, MDMX↓, eff↑,

Showing Research Papers: 601 to 650 of 1280
Prev Page 13 of 26 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1280

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

antiOx↑, 1, ATF3↑, 1, CYP1A1↑, 1, ENOX2↓, 2, Ferroptosis↑, 3, GPx↓, 1, GPx4↓, 2, GSH↓, 3, H2O2↑, 1, HO-1↑, 1, Iron↑, 1, lipid-P↑, 1, MDA↑, 1, NADH↑, 1, NADHdeh?, 1, NRF2↑, 2, NRF2⇅, 1, PYCR1↓, 1, ROS↑, 10, SOD↓, 1, SOD1↓, 1, SOD1↑, 1, xCT↓, 1,

Mitochondria & Bioenergetics ⓘ

AIF↑, 1, ATP↓, 2, CDC25↓, 1, ETC↝, 1, FGFR1↓, 1, Insulin↓, 1, MMP↓, 3, MMP↑, 1, mtDam↑, 1,

Core Metabolism/Glycolysis ⓘ

ACSL4↑, 1, CAIX↓, 1, cMyc↓, 1, ECAR↓, 1, FASN↓, 1, glucose∅, 1, GlucoseCon↓, 1, Glycolysis↓, 3, HK2∅, 1, homoC↓, 3, homoC↝, 1, lactateProd↓, 1, LDH↓, 1, LDHA∅, 1, lipoGen↓, 1, PFK↓, 1, PFKP↓, 1, PKM2↓, 2, TS↓, 1,

Cell Death ⓘ

Akt↓, 2, p‑Akt↓, 1, Apoptosis↓, 1, Apoptosis↑, 7, aSmase↑, 1, BAD↑, 1, Bak↑, 2, BAX↑, 2, Bax:Bcl2↑, 2, Bcl-2↓, 2, Bcl-xL↓, 1, Casp3↑, 5, Casp8↓, 1, Casp8↑, 1, Casp9↑, 3, proCasp9↓, 1, Cyt‑c↑, 4, Fas↑, 2, Ferroptosis↑, 3, MAPK↓, 1, MDM2↓, 1, MOMP↑, 1, Myc↓, 1, necrosis↑, 1, NOXA↑, 1, p27↑, 1, Pyro↑, 1, SK↓, 1, Telomerase↓, 1, TumCD↓, 1, TumCD↑, 3,

Kinase & Signal Transduction ⓘ

FOXD3↑, 1, HER2/EBBR2↓, 1,

Transcription & Epigenetics ⓘ

H3↓, 1, ac‑H3↑, 1, ac‑H4↑, 1, HATs↓, 1, other?, 1, other↑, 1, other↝, 1, other∅, 1, tumCV↓, 1,

Protein Folding & ER Stress ⓘ

CHOP↓, 1, CHOP↑, 2, eIF2α↓, 1, ER Stress↑, 6, GRP78/BiP↓, 1, GRP78/BiP↑, 2, IRE1↑, 1, p‑PERK↓, 1, UPR↓, 1, UPR↑, 2,

Autophagy & Lysosomes ⓘ

ATG5↑, 1, Beclin-1↑, 1, LC3B↑, 1, LC3II↑, 2, p62↑, 1, TumAuto↑, 2,

DNA Damage & Repair ⓘ

DNAdam↑, 3, DNMT1↓, 1, DNMTs↓, 1, MDMX↓, 1, P53↑, 5, PARP↑, 1, cl‑PARP↑, 1, TP53↓, 1,

Cell Cycle & Senescence ⓘ

CDK4↓, 1, cycA1/CCNA1↓, 1, cycD1/CCND1↓, 1, cycE/CCNE↓, 1, P21↑, 2, TumCCA↑, 4,

Proliferation, Differentiation & Cell State ⓘ

CD133↓, 1, CD44↓, 1, CSCs↓, 1, EMT↓, 2, ERK↑, 1, HDAC1↓, 1, IGF-1↓, 2, IGF-1∅, 1, IGF-1R↑, 1, IGF-2↓, 1, IGFBP1↓, 1, IGFBP1↑, 1, miR-34a↑, 1, mTOR↓, 1, NOTCH3↓, 1, PI3K↓, 2, PTEN↑, 1, STAT6↓, 1, TumCG↓, 3, Wnt↑, 1,

Migration ⓘ

AntiAg↑, 2, Ca+2↑, 2, Ki-67↓, 2, MMP2↓, 1, MMP2⇅, 1, MMP9↓, 1, MMP9⇅, 1, MMPs↓, 2, PKA↓, 1, RECK↑, 1, STAC2↓, 1, TGF-β↓, 1, TIMP1↑, 1, TumCI↓, 2, TumCMig↑, 1, TumCP↓, 4, TumCP∅, 1, TumMeta↓, 1, Zeb1↑, 1, β-catenin/ZEB1↓, 1,

Angiogenesis & Vasculature ⓘ

angioG↓, 4, ATF4↑, 1, eNOS↓, 1, EPR↑, 1, Hif1a↓, 2, VEGF↓, 3,

Barriers & Transport ⓘ

BBB↑, 1, CellMemb↑, 3,

Immune & Inflammatory Signaling ⓘ

COX1↓, 1, COX2↓, 1, HMGB1↓, 1, IFN-γ↓, 1, IKKα↑, 1, IL17↑, 1, IL2↑, 1, IL6↓, 1, IL6↑, 1, Imm↑, 3, Inflam↓, 2, IκB↑, 1, JAK↓, 1, JAK2↓, 1, NF-kB↓, 4,

Cellular Microenvironment ⓘ

Hormonal & Nuclear Receptors ⓘ

Drug Metabolism & Resistance ⓘ

BioAv↓, 1, BioAv↑, 2, BioAv∅, 1, ChemoSen↑, 7, Dose?, 2, Dose↓, 1, Dose↑, 2, Dose↝, 5, eff↓, 9, eff↑, 41, eff↝, 7, eff∅, 1, Half-Life↝, 1, Half-Life∅, 1, RadioS↑, 1, selectivity↑, 7,

Clinical Biomarkers ⓘ

BMD↑, 1, HER2/EBBR2↓, 1, HOMA↓, 1, IL6↓, 1, IL6↑, 1, Ki-67↓, 2, LDH↓, 1, Myc↓, 1, NOS2↓, 1, TP53↓, 1,

Functional Outcomes ⓘ

AntiCan↑, 1, cardioP↑, 1, chemoP↑, 1, ChemoSideEff↓, 1, cognitive↑, 1, hepatoP↓, 1, MusCon↓, 2, OS↑, 3, PARP16↓, 1, Remission↑, 2, Risk↓, 4, toxicity↓, 2, toxicity∅, 1, TumVol↓, 1, TumW↓, 2,
Total Targets: 229

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress ⓘ

antiOx↑, 1, MPO↓, 1, ROS↓, 2,

Mitochondria & Bioenergetics ⓘ

Core Metabolism/Glycolysis ⓘ

glucose↓, 1, LDH↓, 1, LDL↓, 1, SIRT1↑, 1,

Cell Death ⓘ

BAX↓, 1, Cyt‑c↓, 1,

Transcription & Epigenetics ⓘ

other↓, 1, other↑, 2, other↝, 1,

Proliferation, Differentiation & Cell State ⓘ

VGCC↑, 1, VGCC⇅, 1,

Migration ⓘ

Ca+2?, 1, Ca+2↑, 1,

Angiogenesis & Vasculature ⓘ

Barriers & Transport ⓘ

CellMemb↑, 1,

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1, NF-kB↓, 1,

Cellular Microenvironment ⓘ

Synaptic & Neurotransmission ⓘ

BDNF↑, 4, BrainVol↑, 1, GABA↑, 1, TrkB↑, 1,

Drug Metabolism & Resistance ⓘ

BioAv↓, 1, BioAv↝, 1, Dose↓, 1, Dose∅, 1, eff↑, 8,

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

AntiAge↑, 1, cardioP↑, 1, cognitive↑, 1, memory↑, 2, MusCon↓, 1, neuroP↑, 1, toxicity∅, 1,
Total Targets: 39

Scientific Paper Hit Count for: eff, efficacy

69 Silver-NanoParticles
58 Magnetic Fields
43 Sulforaphane (mainly Broccoli)
40 Curcumin
35 Vitamin C (Ascorbic Acid)
32 Thymoquinone
31 Chemotherapy
28 Shikonin
27 immunotherapy
26 chitosan
25 Piperlongumine
24 Artemisinin
24 EGCG (Epigallocatechin Gallate)
23 Selenium NanoParticles
23 Selenite (Sodium)
22 Resveratrol
22 Baicalein
22 Quercetin
20 Copper and Cu NanoParticles
20 Ashwagandha(Withaferin A)
20 Berberine
19 Radiotherapy/Radiation
18 Capsaicin
18 Magnetic Field Rotating
17 Apigenin (mainly Parsley)
17 Phenylbutyrate
17 Chlorogenic acid
17 Dichloroacetate
16 diet FMD Fasting Mimicking Diet
16 Gambogic Acid
16 Bicarbonate(Sodium)
15 Selenium
15 Lycopene
14 Propolis -bee glue
14 Exercise
14 Phenethyl isothiocyanate
13 3-bromopyruvate
13 Metformin
13 Caffeic acid
12 Citric Acid
12 Betulinic acid
12 Fisetin
11 Folic Acid, Vit B9
11 Auranofin
11 borneol
11 salinomycin
11 Rosmarinic acid
10 Alpha-Lipoic-Acid
10 Melatonin
10 Luteolin
10 Atorvastatin
10 Vitamin K2
10 Silymarin (Milk Thistle) silibinin
10 diet Methionine-Restricted Diet
10 doxorubicin
10 Honokiol
10 VitK3,menadione
9 Gold NanoParticles
9 SonoDynamic Therapy UltraSound
9 Cisplatin
9 Boron
9 Vitamin D3
9 Ellagic acid
9 Carvacrol
9 Disulfiram
9 Hydrogen Gas
9 Urolithin
8 Photodynamic Therapy
8 Hyperthermia
8 Chlorophyllin
8 Chrysin
8 Plumbagin
8 Parthenolide
7 Carnosic acid
7 Piperine
7 Electrical Pulses
6 5-fluorouracil
6 Coenzyme Q10
6 Vitamin B12
6 Fenbendazole
6 Allicin (mainly Garlic)
6 Docetaxel
6 beta-glucans
6 Bifidobacterium
6 Celastrol
6 HydroxyCitric Acid
6 Spermidine
6 Juglone
5 Astragalus
5 chemodynamic therapy
5 Akkermansia
5 Bevacizumab (brand Avastin)
5 Ascorbyl Palmitate
5 Astaxanthin
5 Berbamine
5 beta-carotene(VitA)
5 Bortezomib
5 Boswellia (frankincense)
5 Thymol-Thymus vulgaris
5 diet Plant based
5 MCToil
5 Magnolol
5 Moringa oleifera
4 2-DeoxyGlucose
4 almonertinib
4 Andrographis
4 Gemcitabine (Gemzar)
4 Aspirin -acetylsalicylic acid
4 Dipyridamole
4 Butyrate
4 capecitabine
4 Cat’s Claw
4 Cannabidiol
4 diet Short Term Fasting
4 Propyl gallate
4 Pterostilbene
4 Sulfasalazine
4 Whole Body Vibration
3 cetuximab
3 Anthocyanins
3 Anti-oxidants
3 Aloe anthraquinones
3 Biochanin A
3 bempedoic acid
3 Lutein
3 Zeaxanthin
3 Bufalin/Huachansu
3 temozolomide
3 hydroxychloroquine
3 Chocolate
3 Choline
3 Calorie Restriction Mimetics
3 erastin
3 Ginseng
3 Lecithin
3 nicotinamide adenine dinucleotide
3 Naringin
3 Radio Frequency
3 Taurine
3 Vitamin B1/Thiamine
2 5-Aminolevulinic acid
2 Glucose
2 Zinc
2 Aromatherapy
2 Sorafenib (brand name Nexavar)
2 Arsenic trioxide
2 Baicalin
2 brusatol
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Caffeine
2 Calcium
2 carboplatin
2 Celecoxib
2 Oxygen, Hyperbaric
2 Emodin
2 ferumoxytol
2 Kaempferol
2 Genistein (soy isoflavone)
2 γ-linolenic acid (Borage Oil)
2 Orlistat
2 Potassium
2 Methylene blue
2 metronomic chemo
2 Methylsulfonylmethane
2 Mushroom Lion’s Mane
2 Niclosamide (Niclocide)
2 Nimbolide
2 Phosphatidylserine
2 Aflavin-3,3′-digallate
1 Serotonin, 5-hydroxytryptamine
1 dietMediterranean
1 EMF
1 Anzaroot, Astragalus fasciculifolius Bioss
1 Trichostatin A
1 wortmannin
1 Resiquimod
1 Ajoene (compound of Garlic)
1 Acetyl-l-carnitine
1 Amodiaquine
1 Vitamin A, Retinoic Acid
1 Trastuzumab
1 D-limonene
1 Huperzine A/Huperzia serrata
1 probiotics
1 Brucea javanica
1 Bacopa monnieri
1 Bromelain
1 Bruteridin(bergamot juice)
1 Rutin
1 urea
1 Carnosine
1 Cannabichromene
1 Beta‐Lapachone
1 Cinnamon
1 Camptothecin
1 irinotecan
1 Black phosphorus
1 Dichloroacetophenone(2,2-)
1 Date Fruit Extract
1 diet Fermented Foods
1 diet Ketogenic
1 PXD, phenoxodiol
1 Ferulic acid
1 Vitamin E
1 flavonoids
1 Flickering Light Stimulation
1 verapamil
1 Garcinol
1 tamoxifen
1 Hydroxycinnamic-acid
1 HydroxyTyrosol
1 itraconazole
1 Laetrile B17 Amygdalin
1 lambertianic acid
1 Docosahexaenoic Acid
1 Matrine
1 Methyl Jasmonate
1 methotrexate
1 Magnesium
1 Methylglyoxal
1 Mushroom Reishi
1 Myricetin
1 Oleocanthal
1 Peppermint
1 sericin
1 Paclitaxel
1 Psoralidin
1 enzalutamide
1 Oxaliplatin
1 Scoulerine
1 polyethylene glycol
1 acetaminophen
1 Formononetin
1 acetazolamide
1 Iron
1 Squalene
1 Glutathione
1 statins
1 Sutherlandioside D
1 triptolide
1 Tumor Treating Fields
1 Ursolic acid
1 Vitamin B3,Niacin
1 Vitamin B5,Pantothenic Acid
1 Vitamin B6,pyridoxine
1 Wogonin

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

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