| Source: |
| Type: |
| Drug dosage vs efficacy, and actual dosage number of research papers. |
| 7477- | HRT, | Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis |
| - | Trial, | Nor, | NA |
| 7524- | HT, | The Pharmaceutical Formulation Plays a Pivotal Role in Hydroxytyrosol Pharmacokinetics |
| - | Trial, | Nor, | NA |
| 7540- | HT, | Discovery of hydroxytyrosol as thioredoxin reductase 1 inhibitor to induce apoptosis and G1/S cell cycle arrest in human colorectal cancer cells via ROS generation |
| - | in-vitro, | CRC, | HCT8 | - | in-vitro, | CRC, | HCT116 |
| 7526- | HT, | Hydroxytyrosol in functional hydroxytyrosol-enriched biscuits is highly bioavailable and decreases oxidised low density lipoprotein levels in humans |
| - | Trial, | Nor, | NA |
| 7529- | HT, | Diet Supplementation with Hydroxytyrosol Ameliorates Brain Pathology and Restores Cognitive Functions in a Mouse Model of Amyloid-β Deposition |
| - | in-vivo, | AD, | NA |
| 7536- | HT, | Effects of Desert Olive Tree Pearls Containing High Hydroxytyrosol Concentrations on the Cognitive Functions of Middle-Aged and Older Adults |
| - | Trial, | AD, | NA |
| 7539- | HT, | Polyphenols Extracts from Oil Production Waste Products (OPWPs) Reduce Cell Viability and Exert Anti-Inflammatory Activity via PPARγ Induction in Colorectal Cancer Cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | LoVo |
| 7541- | HT, | Hydroxytyrosol Supplementation Modifies Plasma Levels of Tissue Inhibitor of Metallopeptidase 1 in Women with Breast Cancer |
| - | Trial, | BC, | NA |
| 7479- | Hup, | A phase II trial of huperzine A in mild to moderate Alzheimer disease |
| - | Trial, | AD, | NA |
| 7480- | Hup, | Pharmacokinetics of huperzine A following oral administration to human volunteers |
| - | Trial, | AD, | NA |
| 3803- | Hup, | Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 7563- | HYP, | Hyperoside alleviates macrophages and microglia-mediated neuroinflammation and oxidative stress through activating PI3K/AKT and Nrf2/HO-1 signaling pathway post spinal cord injury |
| - | vitro+vivo, | Nor, | NA |
| 7602- | I3C, | Dose-ranging study of indole-3-carbinol for breast cancer prevention |
| - | Trial, | BC, | NA |
| 7611- | I3C, | Long-term responses of women to indole-3-carbinol or a high fiber diet |
| - | Trial, | Nor, | NA |
| 7587- | I3C, | Indole-3-Carbinol, a Phytochemical Aryl Hydrocarbon Receptor-Ligand, Induces the mRNA Overexpression of UBE2L3 and Cell Proliferation Arrest |
| - | in-vitro, | Cerv, | HeLa |
| 7595- | I3C, | Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans |
| - | Human, | Nor, | NA |
| 7580- | I3C, | Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmethane |
| - | Trial, | Var, | NA |
| 7581- | I3C, | A phase I study of indole-3-carbinol in women: tolerability and effects |
| - | Trial, | Nor, | NA |
| 7594- | I3C, | Effects of indole-3-carbinol on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers |
| - | Human, | Nor, | NA |
| 7771- | IBC, | Isobavachalcone induces concurrent apoptosis and pyroptosis in anaplastic thyroid cancer cells by modulating the caspase-mediated cleavage of PARP and GSDME |
| - | vitro+vivo, | Thyroid, | CAL-62 |
| 7709- | IBC, | Isobavachalcone ameliorates cognitive deficits, and Aβ and tau pathologies in triple-transgenic mice with Alzheimer's disease |
| - | in-vivo, | AD, | NA |
| 7711- | IBC, | Isobavachalcone, a natural sirtuin 2 inhibitor, exhibits anti-triple-negative breast cancer efficacy in vitro and in vivo |
| - | vitro+vivo, | BC, | NA |
| 7616- | Ins, | A phase I study of myo-inositol for lung cancer chemoprevention |
| - | Trial, | Nor, | NA |
| 7615- | Ins, | A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia |
| - | Trial, | Nor, | NA |
| 7648- | Ins, | Suppression of lung and liver carcinogenesis in mice by oral administration of myo-inositol |
| - | in-vivo, | Liver, | NA |
| 7643- | Ins, | IP6, | Efficacy of IP6 + inositol in the treatment of breast cancer patients receiving chemotherapy: prospective, randomized, pilot clinical stud |
| - | Trial, | BC, | NA |
| 7636- | Ins, | Myo-Inositol: Pharmacokinetics, Biological Functions, and Therapeutic Potential in Liver Protection: Insights from Preclinical Models |
| - | Review, | Nor, | NA |
| 7635- | Ins, | The Role of Inositols in Endocrine and Neuroendocrine Tumors |
| - | Review, | Thyroid, | NA |
| 7637- | Ins, | Investigating the mechanism of inositol against paclitaxel chemoresistance on triple-negative breast cancer by using 7T multiparametric MRI and mitochondrial changes |
| - | vitro+vivo, | BC, | 4T1 |
| 7638- | Ins, | d-Chiro-Inositol in Clinical Practice: A Perspective from the Experts Group on Inositol in Basic and Clinical Research (EGOI) |
| - | Review, | Nor, | NA |
| 7631- | Ins, | IP6, | Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate |
| - | Review, | Var, | NA |
| 7672- | iod, | Adjuvant Effect of Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study |
| - | Trial, | BC, | NA |
| 7673- | iod, | Chemo, | Adjuvant Effect of Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study |
| - | Trial, | BC, | NA |
| 7676- | iod, | Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR) |
| - | in-vivo, | BC, | NA |
| 7680- | iod, | doxoR, | Iodine and doxorubicin, a good combination for mammary cancer treatment: antineoplastic adjuvancy, chemoresistance inhibition, and cardioprotection |
| - | vitro+vivo, | BC, | NA |
| 7684- | iod, | Molecular iodine impairs chemotherapy resistance and adverse effects in breast cancer treatments |
| - | Trial, | BC, | NA |
| 7687- | iod, | ESWT, | Shock Wave Application Increases the Antineoplastic Effect of Molecular Iodine Supplement in Breast Cancer Xenografts |
| - | in-vivo, | BC, | MDA-MB-231 |
| 7654- | IP, | Dietary Supplementation of Inulin Contributes to the Prevention of Estrogen Receptor-Negative Mammary Cancer by Alteration of Gut Microbial Communities and Epigenetic Regulations |
| - | in-vivo, | BC, | NA |
| - | in-vivo, | BC, | NA |
| 7657- | IP, | Dietary inulin suppresses azoxymethane-induced aberrant crypt foci and colon tumors at the promotion stage in young Fisher 344 rats |
| - | in-vivo, | Var, | NA |
| 7662- | IP, | Digestive tolerance of inulin-type fructans: a double-blind, placebo-controlled, cross-over, dose-ranging, randomized study in healthy volunteers |
| - | Trial, | Nor, | NA |
| 7666- | IP, | Short-chain fatty acid kinetics and concentrations are higher after inulin supplementation in young and older adults: a randomized trial |
| - | Trial, | Nor, | NA |
| 7668- | IP, | A phase 2 randomized, placebo-controlled trial of inulin for the prevention of gut pathogen colonization and infection among patients admitted to the intensive care unit for sepsis |
| - | Trial, | Sepsis, | NA |
| 7714- | IP6, | ACNs, | Enhanced absorption of anthocyanins after oral administration of phytic acid in rats and humans |
| - | in-vivo, | Nor, | NA |
| 7721- | IP6, | Ins, | Effect of phytic acid and inositol on the proliferation and apoptosis of cells derived from colorectal carcinoma |
| - | in-vitro, | CRC, | HT-29 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | SW-620 |
| 7640- | IP6, | Ins, | Effects of Inositol Hexaphosphate and Myo-Inositol Administration in Breast Cancer Patients during Adjuvant Chemotherapy |
| - | Trial, | BC, | NA |
| 7702- | IP6, | Ins, | capec, | Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model |
| - | in-vivo, | CRC, | NA |
| 7743- | ISL, | Pharmacokinetics, biodistribution and bioavailability of isoliquiritigenin after intravenous and oral administration |
| - | in-vivo, | Nor, | NA |
| 7753- | ISL, | LE, | Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants |
| - | in-vivo, | Nor, | NA |
| 7748- | ISL, | GEM, | Isoliquiritigenin combined with gemcitabine inhibited lung cancer by suppressing JAK2/STAT3 signaling via lncRNA-p21/miRNA-4534 axis |
| - | in-vitro, | Lung, | NA |
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1114 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid