| Source: |
| Type: |
| Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors. |
| 2879- | HNK, | Honokiol Inhibits Lung Tumorigenesis through Inhibition of Mitochondrial Function |
| - | in-vitro, | Lung, | H226 | - | in-vivo, | NA, | NA |
| 2885- | HNK, | Honokiol: a novel natural agent for cancer prevention and therapy |
| - | Review, | Var, | NA |
| 2865- | HNK, | Liposomal Honokiol induces ROS-mediated apoptosis via regulation of ERK/p38-MAPK signaling and autophagic inhibition in human medulloblastoma |
| - | in-vitro, | MB, | DAOY | - | vitro+vivo, | NA, | NA |
| 2895- | HNK, | Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity |
| - | in-vitro, | Lung, | PC9 |
| 2897- | HNK, | Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells |
| - | in-vitro, | Lung, | PC9 | - | in-vitro, | Lung, | A549 |
| 2898- | HNK, | Honokiol Suppression of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastric Cancer Cell Biological Activity and Its Mechanism |
| - | in-vitro, | GC, | AGS | - | in-vitro, | GC, | NCI-N87 | - | in-vitro, | BC, | MGC803 | - | in-vitro, | GC, | SGC-7901 |
| 2082- | HNK, | Revealing the role of honokiol in human glioma cells by RNA-seq analysis |
| - | in-vitro, | GBM, | U87MG | - | in-vitro, | GBM, | U251 |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | LoVo | - | in-vivo, | CRC, | HCT116 |
| 7472- | Hops, | Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupulus L.) flavonoids |
| - | in-vitro, | BC, | SkBr3 |
| 5053- | HPT, | Rad, | Chemo, | Association of elevated reactive oxygen species and hyperthermia induced radiosensitivity in cancer stem-like cells |
| - | in-vitro, | Var, | NA |
| 7542- | HT, | Hydroxytyrosol Induces Apoptosis and Cell Cycle Arrest and Suppresses Multiple Oncogenic Signaling Pathways in Prostate Cancer Cells |
| - | in-vitro, | Pca, | LNCaP | - | in-vitro, | Pca, | C4-2B | - | in-vitro, | Nor, | RWPE-1 |
| 7540- | HT, | Discovery of hydroxytyrosol as thioredoxin reductase 1 inhibitor to induce apoptosis and G1/S cell cycle arrest in human colorectal cancer cells via ROS generation |
| - | in-vitro, | CRC, | HCT8 | - | in-vitro, | CRC, | HCT116 |
| 7527- | HT, | Hydroxytyrosol, a product from olive oil, reduces colon cancer growth by enhancing epidermal growth factor receptor degradation |
| - | vitro+vivo, | Colon, | HT29 | - | in-vitro, | Colon, | Caco-2 |
| 7535- | HT, | Hydroxytyrosol acetate from olive leaves (Olea Europaea L.) induces apoptosis via mitochondrial pathway in BEL7402 cell line |
| - | in-vitro, | Liver, | Bel-7402 |
| 4635- | HT, | Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention in Women at High Risk of Cancer |
| - | Trial, | BC, | NA |
| 4637- | HT, | Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells |
| - | in-vitro, | Nor, | RWPE-1 | - | in-vitro, | Pca, | LNCaP | - | in-vitro, | Pca, | 22Rv1 | - | in-vitro, | Pca, | PC3 |
| 4639- | HT, | Hydroxytyrosol Induces Apoptosis, Cell Cycle Arrest and Suppresses Multiple Oncogenic Signaling Pathways in Prostate Cancer Cells |
| - | in-vitro, | Pca, | LNCaP | - | in-vitro, | Pca, | C4-2B |
| 4642- | HT, | Hydroxytyrosol, a natural molecule from olive oil, suppresses the growth of human hepatocellular carcinoma cells via inactivating AKT and nuclear factor-kappa B pathways |
| - | in-vitro, | HCC, | HepG2 | - | NA, | NA, | Hep3B | - | NA, | NA, | SK-HEP-1 |
| 7570- | HYP, | Hyperoside suppresses BMP-7-dependent PI3K/AKT pathway in human hepatocellular carcinoma cells |
| - | in-vitro, | Liver, | HepG2 |
| 7569- | HYP, | Inhibitory effects of hyperoside on lung cancer by inducing apoptosis and suppressing inflammatory response via caspase-3 and NF-κB signaling pathway |
| - | vitro+vivo, | Lung, | A549 |
| 7548- | HYP, | Mechanistic evaluation of hyperoside against non-small cell lung cancer: a combined approach of network pharmacology and in vitro experimental validation |
| - | in-vitro, | NSCLC, | A549 |
| 7547- | HYP, | Hyperoside suppresses NSCLC progression by inducing ATG13-mediated autophagy and apoptosis |
| - | vitro+vivo, | NSCLC, | NA |
| 7549- | HYP, | Rad, | Study on the mechanism of hyperoside in affecting the biological progression and radiosensitivity of esophageal carcinoma by modulating the STAT3/AKT/ERK pathway |
| - | vitro+vivo, | ESCC, | TE1 | - | vitro+vivo, | ESCC, | KYSE150 |
| 7551- | HYP, | Hyperoside exhibits anticancer activity in non‑small cell lung cancer cells with T790M mutations by upregulating FoxO1 via CCAT1 |
| - | vitro+vivo, | NSCLC, | NA |
| 7552- | HYP, | Hyperoside exerts potent anticancer activity in skin cancer |
| - | vitro+vivo, | Melanoma, | NA |
| 7556- | HYP, | Hyperoside induces apoptosis and inhibits growth in pancreatic cancer via Bcl-2 family and NF-κB signaling pathway both in vitro and in vivo |
| - | vitro+vivo, | PC, | NA |
| 7560- | HYP, | Hyperoside: A Review of Its Structure, Synthesis, Pharmacology, Pharmacokinetics and Toxicity |
| - | Review, | Nor, | NA | - | Review, | AD, | NA |
| 7607- | I3C, | Indole-3-carbinol induces G1 cell cycle arrest and apoptosis through aryl hydrocarbon receptor in THP-1 monocytic cell line |
| - | in-vitro, | AML, | THP1 |
| 7583- | I3C, | Indole-3-carbinol prevented tumor progression and potentiated PD1ab therapy by upregulating PTEN in colorectal cancer |
| - | vitro+vivo, | CRC, | NA |
| 7584- | I3C, | Functional effect of indole-3 carbinol in the viability and invasive properties of cultured cancer cells |
| - | in-vitro, | Cerv, | HeLa | - | in-vitro, | CRC, | HCT8 | - | in-vitro, | Liver, | HepG2 |
| 7589- | I3C, | Indole-3-carbinol inhibits cell proliferation and induces apoptosis in Hep-2 laryngeal cancer cells |
| - | vitro+vivo, | Laryn, | HEp2 |
| 7768- | IBC, | Isobavachalcone Induces ROS-Mediated Apoptosis via Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC-3 Cells |
| - | in-vitro, | Pca, | PC3 |
| 7806- | IBC, | Isoalantolactone inhibits pancreatic cancer proliferation by regulation of PI3K and Wnt signal pathway |
| - | in-vitro, | PC, | NA |
| 7807- | IBC, | Isobavachalcone exerts anti‑proliferative and pro‑apoptotic effects on human liver cancer cells by targeting the ERKs/RSK2 signaling pathway |
| - | in-vitro, | Liver, | HepG2 | - | in-vitro, | Liver, | Hep3B | - | in-vitro, | Nor, | L02 |
| 7808- | IBC, | Isobavachalcone inhibits the proliferation and invasion of tongue squamous cell carcinoma cells |
| - | in-vitro, | Tong, | Tca8113 |
| 7772- | IBC, | Isobavachalcone inhibits acute myeloid leukemia: Potential role for ROS-dependent mitochondrial apoptosis and differentiation |
| - | vitro+vivo, | AML, | NA |
| 7776- | IBC, | Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation |
| - | vitro+vivo, | PC, | Panc02 |
| 7775- | IBC, | Isobavachalcone Induces Multiple Cell Death in Human Triple-Negative Breast Cancer MDA-MB-231 Cells |
| - | vitro+vivo, | BC, | MDA-MB-231 |
| 7774- | IBC, | Isobavachalcone isolated from Psoralea corylifolia inhibits cell proliferation and induces apoptosis via inhibiting the AKT/GSK-3β/β-catenin pathway in colorectal cancer cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 |
| 33- | InA, | Inoscavin A, a pyrone compound isolated from a Sanghuangporus vaninii extract, inhibits colon cancer cell growth and induces cell apoptosis via the hedgehog signaling pathway |
| - | vitro+vivo, | Colon, | NA |
| 7671- | iod, | Uptake and antiproliferative effect of molecular iodine in the MCF-7 breast cancer cell line |
| - | in-vitro, | BC, | MCF7 |
| 7676- | iod, | Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR) |
| - | in-vivo, | BC, | NA |
| 7677- | iod, | Activation of peroxisome proliferator-activated receptor gamma is crucial for antitumoral effects of 6-iodolactone |
| - | in-vitro, | BC, | MCF7 |
| 7688- | iod, | CEL, | Iodine prevents the increase of testosterone-induced oxidative stress in a model of rat prostatic hyperplasia |
| - | in-vivo, | Pca, | NA |
| 7715- | IP6, | Inositol hexaphosphate (IP6) inhibits cellular proliferation in melanoma |
| - | in-vitro, | Melanoma, | HTB68 |
| 7716- | IP6, | Inositol hexaphosphate (IP6): a novel treatment for pancreatic cancer |
| - | in-vitro, | Pca, | MIA PaCa-2 | - | in-vitro, | PC, | PANC1 |
| - | in-vivo, | Pca, | DU145 |
| 7713- | IP6, | PacT, | Inositol hexaphosphate and paclitaxel: symbiotic treatment of oral cavity squamous cell carcinoma |
| - | in-vitro, | Oral, | Ca9-22 | - | in-vitro, | Oral, | HN5 |
| 7712- | IP6, | Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice |
| - | in-vivo, | Pca, | NA |
| 7719- | IP6, | Effect of inositol hexaphosphate (IP(6)) on human normal and leukaemic haematopoietic cells |
| - | in-vitro, | CML, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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