antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
Scientific Papers found: Click to Expand⟱
3060- RES,    Resveratrol targeting NRF2 disrupts the binding between KEAP1 and NRF2-DLG motif to ameliorate oxidative stress damage in mice pulmonary infection
- in-vitro, Nor, RAW264.7 - in-vivo, NA, NA
*NRF2↑, *antiOx↑, *ROS↓,
3062- RES,    Resveratrol enhances post-injury muscle regeneration by regulating antioxidant and mitochondrial biogenesis
- in-vivo, Nor, NA
*antiOx↑, *Keap1↓, *NRF2↑, *HO-1↑, *GPx↑, *SOD↑,
3063- RES,    Resveratrol: A Review of Pre-clinical Studies for Human Cancer Prevention
- Review, Var, NA
*Inflam↓, *antiOx↑, *AntiAg↑, *chemoPv↑, ChemoSen↑, BioAv↑, Half-Life↝, COX2/PTGS2↓, cycD1/CCND1↓, CDK2↓, CDK4↓, CDK6↓, P21↑, MMP9↓, NF-kB↓, Telomerase↓, PSA↓, MAPK↑, P53↑,
3069- RES,    Resveratrol Inhibits NLRP3 Inflammasome-Induced Pyroptosis and miR-155 Expression in Microglia Through Sirt1/AMPK Pathway
- in-vitro, Nor, N9
*antiOx↑, *Inflam↓, *ROS↓, *NF-kB↓, *AMPK↑, *SIRT1↑, *miR-155↓, *NLRP3↓,
2990- RES,    Resveratrol reduces cerebral edema through inhibition of de novo SUR1 expression induced after focal ischemia
- in-vivo, Stroke, NA
*OS↑, *antiOx↑, Sp1/3/4↓,
4663- RES,    Exploring resveratrol’s inhibitory potential on lung cancer stem cells: a scoping review of mechanistic pathways across cancer models
- Review, Var, NA
*antiOx↑, *Inflam↓, *chemoPv↑, CSCs↓, Wnt↓, β-catenin/ZEB1↓, NOTCH↓, PI3K↓, Akt↓, mTOR↓, GSK‐3β↝, Snail↓, HH↓, p‑GSK‐3β↓, N-cadherin↓, EMT↓, CD133↓, CD44↓, ALDH1A1↓, OCT4↓, SOX4↓, Shh↓, Smo↓, Gli1↓, GLI2↓,
4670- RES,  CUR,  EGCG,  TQ,    Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiAge↑, *SIRT1↑, *SIRT3↑, *FOXO↑, *ROS↓,
4289- RES,    Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells
- in-vitro, AD, NA
*antiOx↑, *p‑tau↓, *GSK‐3β↓, *CaMKII ↓, *PP2A↑, *neuroP↑,
4286- RES,    Neuroprotective Properties of Resveratrol and Its Derivatives—Influence on Potential Mechanisms Leading to the Development of Alzheimer’s Disease
- Review, AD, NA
*neuroP↑, *Inflam↓, *antiOx↑, *GSH↑, *HO-1↑, *iNOS↓, *BDNF↑, *p‑CREB↑, *PKA↑, *Bcl-2↑, *BAX↓, *IL1β↓, *IL6↓, *MMP9↓, *memory↑, *AMPK↑, *PGC-1α↓, *NF-kB↓, *Aβ↓, *SIRT1↑, *p‑tau↓, *PP2A↑, *lipid-P↓, *NLRP3↓, *BACE/β-secretase↓,
4284- RES,    Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex
- in-vitro, AD, HEK293 - NA, Stroke, NA - in-vivo, AD, NA
*p‑tau↓, *PP2A↑, *neuroP↑, *antiOx↑, COX2/PTGS2↓, *AntiAg↑, *SIRT1↑, *AMPK↑, *Acetyl-CoA↓, *FAO↑, *ADAM10↑, *BACE/β-secretase↓, *Aβ↓, *memory↑, *Inflam↓, *ROS↓,
1749- RosA,    Rosmarinic Acid and Related Dietary Supplements: Potential Applications in the Prevention and Treatment of Cancer
- Review, Var, NA
antiOx↑, eff↑, *toxicity↝, *BioAv↑, *ROS↓, SOD↑, Catalase↑, GPx↑, lipid-P↓, P450↓, chemoP↑, hepatoP↑, ChemoSen↑,
1745- RosA,    Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications
- Review, Var, NA - Review, AD, NA
ChemoSideEff↓, ChemoSen↑, antiOx↑, MMP2↓, MMP9↓, p‑AMPK↑, DNMTs↓, tumCV↓, COX2/PTGS2↓, E-cadherin↑, Vim↓, N-cadherin↓, EMT↓, Casp3↑, Casp9↓, ROS↓, GSH↑, ERK↓, Akt↓, ROS↓, NF-kB↓, p‑IκB↓, p50↓, p65↓, neuroP↑, Dose↝,
1744- RosA,    Therapeutic Applications of Rosmarinic Acid in Cancer-Chemotherapy-Associated Resistance and Toxicity
- Review, Var, NA
chemoR↓, ChemoSideEff↓, RadioS↑, ROS↓, ChemoSen↑, BioAv↑, Half-Life↝, antiOx↑, ROS↑, Fenton↑, DNAdam↑, Apoptosis↑, CSCs↓, HH↓, Bax:Bcl2↑, MDR1↓, P-gp/ABCB1↓, eff↑, eff↑, FOXO4↑, *eff↑, *ROS↓, *JNK↓, *ERK↓, *GSH↑, *H2O2↑, *MDA↓, *SOD↑, *HO-1↑, *CardioT↓, selectivity↑,
1743- RosA,    New insights into the competition between antioxidant activities and pro-oxidant risks of rosmarinic acid
- Analysis, Var, NA
ROS↑, Fenton↑, eff↑, antiOx↑, Iron↓, ROS↑,
3618- RosA,    Antioxidant and Antimicrobial Properties of Rosemary (Rosmarinus officinalis, L.): A Review
- Review, AD, NA
*hepatoP↑, *antiOx↑, *angioG↓, *other↓, *Inflam↓, *ROS↓, *IronCh↑, *lipid-P↓, *antiOx↑,
3620- RosA,    Rosmarinus officinalis and Methylphenidate Exposure Improves Cognition and Depression and Regulates Anxiety-Like Behavior in AlCl3-Induced Mouse Model of Alzheimer's Disease
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *memory↑, *Aβ∅, *GutMicro↑,
3755- RosA,  CUR,    Development of Acetylcholinesterase (AChE) Inhibitor
- Study, AD, NA
*AChE↓, *antiOx↑, *Inflam↓,
3016- RosA,    Rosmarinic Acid Inhibits Cell Growth and Migration in Head and Neck Squamous Cell Carcinoma Cell Lines by Attenuating Epidermal Growth Factor Receptor Signaling
- in-vitro, HNSCC, UM-SCC-6 - in-vitro, HNSCC, UM-SCC-10B
chemoP↓, EGF↓, tumCV↓, TumCMig↓, ROS↓, PI3K↓, Akt↓, ERK↓, antiOx↑, p‑EGFR↓,
3017- RosA,  Per,    Molecular Mechanism of Antioxidant and Anti-Inflammatory Effects of Omega-3 Fatty Acids in Perilla Seed Oil and Rosmarinic Acid Rich Fraction Extracted from Perilla Seed Meal on TNF-α Induced A549 Lung Adenocarcinoma Cells
- in-vitro, Lung, A549
TumCD∅, ROS↓, IL1β↓, IL6↓, IL8↓, TNF-α↓, COX2/PTGS2↓, SOD2↓, FOXO1↓, NF-kB↓, JNK↓, antiOx↑, tumCV∅,
3018- RosA,    Rosemary (Rosmarinus officinalis L.) polyphenols and inflammatory bowel diseases: Major phytochemicals, functional properties, and health effects
- Review, IBD, NA
*Inflam↓, *GutMicro↑, *antiOx↑, *NF-kB↓, *NLRP3↓, *STAT3↓, *NRF2↑,
3026- RosA,    Modulatory Effect of Rosmarinic Acid on H2O2-Induced Adaptive Glycolytic Response in Dermal Fibroblasts
- in-vitro, Nor, NA
*ROS↓, *ATP↑, *NADPH↓, *HK2↓, *PFK2↓, *LDHA↓, *GSR↑, *GPx↑, *Prx↑, *Trx↑, *antiOx↑, *GSH↑, *ROS↓, *GlucoseCon↓, *lactateProd↓, *Glycolysis↝, *ATP↑, *NADPH↓, *PPP↓,
3014- RosA,    Rosmarinic Acid Supplementation Acts as an Effective Antioxidant for Restoring the Antioxidation/Oxidation Balance in Wistar Rats with Cadmium-Induced Toxicity
- in-vivo, Nor, NA
*antiOx↑, *Thiols↑, *GSH↑, *TAC↑, *SOD↑, *GPx↑, *Catalase↑, *ALP↓, *ALAT↓, *AST↓, *creat↓, *BUN↓, *H2O2↓, *MDA↓, *ROS↓, cardioP↑, hepatoP↑, neuroP↑,
3013- RosA,    Rosmarinic acid inhibits angiogenesis and its mechanism of action in vitro
- in-vitro, NA, NA
*BioAv↑, *antiOx↑, *Inflam↓, *ROS↓, *VEGF↓, *IL8↓,
3003- RosA,    Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
- Review, Var, NA - Review, AD, NA - Review, Park, NA
*Inflam↓, *antiOx↑, *neuroP↑, *IL6↓, *IL1β↓, *NF-kB↓, *PGE2↓, *COX2/PTGS2↓, *MMP↑, *memory↑, *ROS↓, *Aβ↓, *HMGB1↓, TumCG↓, MARK4↓, Zeb1↓, MDM2↓, BNIP3↑, ASC↑, NLRP3↓, PI3K↓, Akt↓, Casp1↓, E-cadherin↑, STAT3↓, TLR4↓, MMP↓, ICAM-1↓, AMPK↓, IL6↑, MMP2↓, Warburg↓, Bcl-xL↓, Bcl-2↓, TumCCA↑, EMT↓, TumMeta↓, mTOR↓, HSP27↓, Casp3↑, GlucoseCon↓, lactateProd↓, VEGF↓, p‑p65↓, GIT1↓, FOXM1↓, cycD1/CCND1↓, CDK4↓, MMP9↓, HDAC2↓,
3001- RosA,    Therapeutic Potential of Rosmarinic Acid: A Comprehensive Review
- Review, Var, NA
TumCP↓, Apoptosis↑, TumMeta↓, Inflam↓, *antiOx↑, *AntiAge↑, *ROS↓, BioAv↑, Dose↝, NRF2↑, P-gp/ABCB1↑, ATP↑, MMPs↓, cl‑PARP↓, Hif1a↓, GlucoseCon↓, lactateProd↓, Warburg↓, TNF-α↓, COX2/PTGS2↓, IL6↓, HDAC2↓, GSH↑, ROS↓, ChemoSen↑, *BG↓, *IL1β↓, *TNF-α↓, *IL6↓, *p‑JNK↓, *p38↓, *Catalase↑, *SOD↑, *GSTs↑, *VitC↑, *VitE↑, *GSH↑, *GutMicro↑, *cardioP↑, *ROS↓, *MMP↓, *lipid-P↓, *NRF2↑, *hepatoP↑, *neuroP↑, *P450↑, *HO-1↑, *AntiAge↑, *motorD↓,
3028- RosA,    Network pharmacology mechanism of Rosmarinus officinalis L.(Rosemary) to improve cell viability and reduces apoptosis in treating Alzheimer’s disease
- in-vitro, AD, HT22 - in-vivo, NA, NA
*Aβ↓, *Apoptosis↓, *antiOx↑, *neuroP↑, *eff↑, *IGF-1↑, *MMP9↑, *Src↓, *MAPK↓, *MMP↑,
7380- RS,  GoldNP,    A Comparative Antibacterial, Antioxidant, and Antineoplastic Potential of Rauwolfia serpentina (L.) Leaf Extract with Its Biologically Synthesized Gold Nanoparticles (R-AuNPs)
- in-vitro, Var, NA
AntiCan↑, *antiOx↑,
7378- RS,    Reserpine inhibits DNA repair, cell proliferation, invasion and induces apoptosis in oral carcinogenesis via modulation of TGF-β signaling
*antiOx↑, *AntiBio↑, TGF-β↓, p‑SMAD3↓, p‑SMAD2↓, p‑SMAD4↓, SMAD3↓, Snail↓, ERCC1↓, ERCC4/XPF↓, Ku70/XRCC6↓, PCNA↓, cycD1/CCND1↓, Hif1a↓, IL6↓, Mcl-1↓, BAX↑, Cyt‑c↑, APAF1↑, Casp9↑, Casp3↑, PARP↑, DNArepair↓, TumCP↓, TumCI↓,
4575- RT,  AgNPs,    Rutin-Loaded Silver Nanoparticles With Antithrombotic Function
- in-vivo, NA, NA
*AntiThr↑, *AntiAg↑, *antiOx↑, *Inflam↓,
3936- RT,    Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation
- in-vivo, AD, NA
*memory↑, *Aβ↓, *SOD↑, *GSH↑, *GSSG↓, *MDA↓, *IL1β↓, *IL6↓, *antiOx↑, *Inflam↓,
3933- RT,    The Pharmacological Potential of Rutin
- Review, AD, NA - Review, Stroke, NA - Review, Arthritis, NA
*antiOx↑, *neuroP↑, *cardioP↑, *Inflam↓, *TNF-α↓, *IL1β↓, *IL8↓, *COX2/PTGS2↓, *iNOS↓, *NF-kB↓, *cognitive↑, *Cartilage↑, *AntiAg↑, *ROS↓, *lipid-P↓, *hepatoP↑, *ALAT↓, *AST↓, *RenoP↑,
7830- SA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*cognitive↑, *memory↑, *antiOx↑, *NeuroI↓, *iNOS↓, *3-NT↓, *Ach↑, *ChAT↑, *Dose↝, *neuroP↑,
3639- Sage,    Pharmacological properties of Salvia officinalis and its components
- Review, AD, NA - Review, Var, NA
AntiCan↑, *Inflam↓, *antiOx↑, *cognitive↑, *memory↑, *LDL↓, TumCG↓, MAPK↓, ROS↓, NF-kB↓, COX2/PTGS2↓, angioG↓, *AST↓, *ALAT?,
3640- Sage,    Evaluation of Traditional Herb Extract Salvia officinalis in Treatment of Alzheimers Disease
- in-vivo, AD, NA
*antiOx↑, *memory↑,
4217- Sage,  RosA,  Aroma,    Neuroprotective Potential of Aromatic Herbs: Rosemary, Sage, and Lavender
- Review, AD, NA - Review, Park, NA
*Inflam↓, *antiOx↑, *neuroP↑, *ERK↑, *CREB↑, *BDNF↑, *Aβ↑, *AChE↓, *memory↑, *cognitive↑,
6440- SAO,    Biological Properties of Sandalwood Oil and Microbial Synthesis of Its Major Sesquiterpenoids
- Review, Var, NA
AntiCan↑, *Bacteria↓, *antiOx↑, *Inflam↓, *ROS↓, AntiTum↑, TumCG↓, tumCV↓, β-catenin/ZEB1↓, TumCMig↓, chemoPv↑,
6442- SAO,    Medicinal properties of alpha-santalol, a naturally occurring constituent of sandalwood oil: review
- Review, RCC, NA
AntiTum↑, Apoptosis↑, TumCCA↑, *Inflam↓, selectivity↑, tumCV↓, Casp8↓, Casp9↓, Casp6↓, Casp3↓, cl‑PARP↑, angioG↓, VEGFR2/KDR/Flk1↓, Akt↑, mTOR↓, TumCG↓, *GSTs↑, *antiOx↑, *ROS↓,
3853- SAS,    Sulfur-containing therapeutics in the treatment of Alzheimer's disease
- Review, AD, NA
*antiOx↑,
2140- Se,    Selenium Exposure and Cancer Risk: an Updated Meta-analysis and Meta-regression
- Review, Var, NA
Risk↓, antiOx↑, eff↑, eff↝,
1695- Se,    Serum Selenium Concentration as a Potential Diagnostic Marker for Early-Stage Colorectal Cancer: A Comparative Study
- Trial, CRC, NA
Risk↓, selm↑, Dose↓, antiOx↑, Dose↑, Dose↝,
4615- Se,  Rad,    Selenium as an adjuvant for modification of radiation response
- Review, Nor, NA
*antiOx↑, *radioP↑, *GSH↑, *GPx↑, *Dose↝, selectivity↑, RadioS↑,
4485- Se,    Selenium stimulates the antitumour immunity: Insights to future research
- Review, NA, NA
*antiOx↑, chemoPv↑, ROS↑, Imm↑, selenoP↑, *IL2↑, *IL4↑, *TNF-α↓, *TGF-β↓, *EMT↓, Risk↓, *GPx↑, *TrxR↑,
4717- Se,    A systematic review of Selenium as a complementary treatment in cancer patients
- Review, Var, NA
*antiOx↑, eff↝, radioP↑, chemoP↑, *selenoP↑, *GPx↑, TrxR↑, *ROS↓,
4085- Se,    Role of micronutrients in Alzheimer's disease: Review of available evidence
- Review, AD, NA
*AChE↓, *BChE↓, *antiOx↑, *memory↑, *cognitive↑,
6058- SeNPs,  RES,  QC,  CAR,    Engineered nanoplatforms for brain-targeted co-delivery of phytochemicals in Alzheimer's disease: Rational design, blood-brain barrier penetration, and multi-target therapeutic synergy
- Review, AD, NA
*DDS↑, *cognitive↑, *Aβ↓, *tau↓, *Inflam↓, *antiOx↑, *BioAv↑, *BioAv↑, *neuroP↑, *BioAv↑, *AChE↓,
6048- SeNPs,    Unravelling the in vitro and in vivo potential of selenium nanoparticles in Alzheimer's disease: A bioanalytical review
- Review, AD, NA
*antiOx↑, *Inflam↓, *BBB↑, *Aβ↓, *tau↓, *neuroP↑, *cognitive↑,
6046- SeNPs,  CGA,    Anti-amyloidogenic properties of 5‑caffeoylquinic acid-capped selenium nanoparticles
- Study, AD, NA
*AChE↓, *BChE↓, *Aβ↓, *eff↑, *BBB↑, *Dose↝, *IronCh↑, *antiOx↑,
6044- SeNPs,  Chit,  CGA,    Ability of selenium species to inhibit metal-induced Aβ aggregation involved in the development of Alzheimer's disease
- Study, AD, NA
*antiOx↑, *Aβ↓, *DDS↑, *Dose↝,
4721- SeNPs,    A review on selenium nanoparticles and their biomedical applications
- Review, AD, NA - Review, Diabetic, NA - Review, Arthritis, NA
*antiOx↑, *Inflam↓, *eff↝, *selenoP↑, *Bacteria↓, *neuroP↑, *ROS↓, ChemoSen↑,
4720- SeNPs,    Selenium Nanoparticle in the Management of Oxidative Stress During Cancer Chemotherapy
- Review, Var, NA
*toxicity↓, *antiOx↑, chemoP↑,

Showing Research Papers: 701 to 750 of 868
Prev Page 15 of 18 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 868

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

ERCC4/XPF↓, 1,   Ku70/XRCC6↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 8,   Catalase↑, 1,   Fenton↑, 2,   GPx↑, 1,   GSH↑, 2,   Iron↓, 1,   lipid-P↓, 1,   NRF2↑, 1,   ROS↓, 7,   ROS↑, 4,   selenoP↑, 1,   SOD↑, 1,   SOD2↓, 1,   TrxR↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

selm↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   EGF↓, 1,   MMP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↓, 1,   p‑AMPK↑, 1,   ERCC1↓, 1,   GlucoseCon↓, 2,   lactateProd↓, 2,   Warburg↓, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 4,   Akt↑, 1,   APAF1↑, 1,   Apoptosis↑, 3,   BAX↑, 1,   Bax:Bcl2↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   Casp1↓, 1,   Casp3↓, 1,   Casp3↑, 3,   Casp6↓, 1,   Casp8↓, 1,   Casp9↓, 2,   Casp9↑, 1,   Cyt‑c↑, 1,   JNK↓, 1,   MAPK↓, 1,   MAPK↑, 1,   Mcl-1↓, 1,   MDM2↓, 1,   Telomerase↓, 1,   TumCD∅, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Sp1/3/4↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 4,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP27↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

BNIP3↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   DNArepair↓, 1,   DNMTs↓, 1,   P53↑, 1,   PARP↑, 1,   cl‑PARP↓, 1,   cl‑PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 2,   cycD1/CCND1↓, 3,   P21↑, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH1A1↓, 1,   CD133↓, 1,   CD44↓, 1,   CSCs↓, 2,   EMT↓, 3,   ERK↓, 2,   FOXM1↓, 1,   FOXO1↓, 1,   FOXO4↑, 1,   Gli1↓, 1,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 1,   HDAC2↓, 2,   HH↓, 2,   mTOR↓, 3,   NOTCH↓, 1,   OCT4↓, 1,   PI3K↓, 3,   Shh↓, 1,   Smo↓, 1,   STAT3↓, 1,   TumCG↓, 4,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

E-cadherin↑, 2,   GIT1↓, 1,   GLI2↓, 1,   MARK4↓, 1,   MMP2↓, 2,   MMP9↓, 3,   MMPs↓, 1,   N-cadherin↓, 2,   p‑SMAD2↓, 1,   SMAD3↓, 1,   p‑SMAD3↓, 1,   p‑SMAD4↓, 1,   Snail↓, 2,   SOX4↓, 1,   TGF-β↓, 1,   TumCI↓, 1,   TumCMig↓, 2,   TumCP↓, 2,   TumMeta↓, 2,   Vim↓, 1,   Zeb1↓, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   p‑EGFR↓, 1,   Hif1a↓, 2,   VEGF↓, 1,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

P-gp/ABCB1↓, 1,   P-gp/ABCB1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ASC↑, 1,   COX2/PTGS2↓, 6,   ICAM-1↓, 1,   IL1β↓, 1,   IL6↓, 3,   IL6↑, 1,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 1,   p‑IκB↓, 1,   NF-kB↓, 4,   p50↓, 1,   p65↓, 1,   p‑p65↓, 1,   PSA↓, 1,   TLR4↓, 1,   TNF-α↓, 2,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 3,   chemoR↓, 1,   ChemoSen↑, 6,   Dose↓, 1,   Dose↑, 1,   Dose↝, 3,   eff↑, 5,   eff↝, 2,   Half-Life↝, 2,   MDR1↓, 1,   P450↓, 1,   RadioS↑, 2,   selectivity↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

p‑EGFR↓, 1,   FOXM1↓, 1,   IL6↓, 3,   IL6↑, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiTum↑, 2,   cardioP↑, 1,   chemoP↓, 1,   chemoP↑, 3,   chemoPv↑, 2,   ChemoSideEff↓, 2,   hepatoP↑, 2,   neuroP↑, 2,   radioP↑, 1,   Risk↓, 3,  
Total Targets: 167

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

3-NT↓, 1,   AntiBio↑, 1,   NeuroI↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 43,   Catalase↑, 2,   GPx↑, 6,   GSH↑, 7,   GSR↑, 1,   GSSG↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 1,   HO-1↑, 4,   Keap1↓, 1,   lipid-P↓, 4,   MDA↓, 3,   NRF2↑, 4,   Prx↑, 1,   ROS↓, 19,   selenoP↑, 2,   SIRT3↑, 1,   SOD↑, 5,   TAC↑, 1,   Thiols↑, 1,   Trx↑, 1,   TrxR↑, 1,   VitC↑, 1,   VitE↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 2,   MMP↓, 1,   MMP↑, 2,   PGC-1α↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Acetyl-CoA↓, 1,   ALAT?, 1,   ALAT↓, 2,   AMPK↑, 3,   BUN↓, 1,   CREB↑, 1,   p‑CREB↑, 1,   FAO↑, 1,   GlucoseCon↓, 1,   Glycolysis↝, 1,   HK2↓, 1,   lactateProd↓, 1,   LDHA↓, 1,   LDL↓, 1,   NADPH↓, 2,   PFK2↓, 1,   PPP↓, 1,   SIRT1↑, 4,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   BAX↓, 1,   Bcl-2↑, 1,   iNOS↓, 3,   JNK↓, 1,   p‑JNK↓, 1,   MAPK↓, 1,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

CaMKII ↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   AntiThr↑, 1,   other↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↓, 1,   ERK↓, 1,   ERK↑, 1,   FOXO↑, 1,   GSK‐3β↓, 1,   IGF-1↑, 1,   Src↓, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 4,   Cartilage↑, 1,   miR-155↓, 1,   MMP9↓, 1,   MMP9↑, 1,   PKA↑, 1,   TGF-β↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   HMGB1↓, 1,   IL1β↓, 5,   IL2↑, 1,   IL4↑, 1,   IL6↓, 4,   IL8↓, 2,   Inflam↓, 22,   NF-kB↓, 5,   PGE2↓, 1,   TNF-α↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 5,   ADAM10↑, 1,   BChE↓, 2,   BDNF↑, 2,   ChAT↑, 1,   tau↓, 2,   p‑tau↓, 3,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 9,   Aβ↑, 1,   Aβ∅, 1,   BACE/β-secretase↓, 2,   NLRP3↓, 3,   PP2A↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 5,   DDS↑, 2,   Dose↝, 4,   eff↑, 3,   eff↝, 1,   P450↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT?, 1,   ALAT↓, 2,   ALP↓, 1,   AST↓, 3,   BG↓, 1,   creat↓, 1,   GutMicro↑, 3,   IL6↓, 4,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 3,   cardioP↑, 2,   CardioT↓, 1,   chemoPv↑, 2,   cognitive↑, 7,   hepatoP↑, 3,   memory↑, 10,   motorD↓, 1,   neuroP↑, 12,   OS↑, 1,   radioP↑, 1,   RenoP↑, 1,   toxicity↓, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 2,  
Total Targets: 134

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
37 Lycopene
31 Curcumin
28 Thymoquinone
25 Resveratrol
25 Alpha-Lipoic-Acid
25 Hydrogen Gas
24 Selenium NanoParticles
24 Quercetin
20 Silymarin (Milk Thistle) silibinin
19 Rosmarinic acid
17 Ferulic acid
16 Astaxanthin
16 Chlorogenic acid
15 Silver-NanoParticles
15 EGCG (Epigallocatechin Gallate)
14 Eugenol
14 Honokiol
13 Berberine
13 Carvacrol
12 Baicalein
12 Propolis -bee glue
12 Fisetin
11 Allicin (mainly Garlic)
10 Coenzyme Q10
10 Vitamin C (Ascorbic Acid)
10 Luteolin
9 Crocetin
9 Dandelion Root
9 Magnetic Fields
9 Moringa oleifera
8 Melatonin
8 Selenium
8 chitosan
8 Sulforaphane (mainly Broccoli)
8 Emodin
8 Urolithin
7 Radiotherapy/Radiation
7 Apigenin (mainly Parsley)
7 α-Bisabolol / Chamomile oil
7 Cinnamon
7 Chemotherapy
7 Fucoidan
7 Ginger/6-Shogaol/Gingerol
7 Magnolol
6 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
6 Ashwagandha(Withaferin A)
6 Betulinic acid
6 Boron
6 Caffeic acid
6 Capsaicin
6 Chrysin
6 Cichoric acid / Chicoric acid
6 Hydroxycinnamic-acid
6 Ellagic acid
6 Ginkgo biloba
6 Isoliquiritigenin
6 Piperine
5 doxorubicin
5 Beta-Caryophyllene
5 Thymol-Thymus vulgaris
5 Carnosine
5 Centella asiatica / Gotu kola → asiaticoside
5 Vitamin E
5 Carvone
5 Ginkgo biloba-EGb 761
5 Hibiscus sabdariffa
5 HydroxyTyrosol
5 Pterostilbene
5 Selenite (Sodium)
4 Cisplatin
4 beta-carotene(VitA)
4 Bacopa monnieri
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Date Fruit Extract
4 D-limonene
4 flavonoids
4 Shilajit/Fulvic Acid
4 Gallic acid
4 Garcinol
4 Hyperoside
4 iodine
4 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
4 Mung Bean Sprouts
4 Shikonin
3 Anthocyanins
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Ascorbyl Palmitate
3 Chyawanprash
3 Vitamin K2
3 Carica papaya leaf extract
3 Cucurbitacin
3 Dipyridamole
3 Geraniol
3 Inositol
3 isoquercitrin
3 Lecithin
3 Naringin
3 Nimbolide
3 Rutin
3 Salvia officinalis
3 Taurine
3 Ursolic acid
2 1,8-Cineole
2 5-fluorouracil
2 Anethole/trans-Anethole
2 Fennel Oil/Foeniculum vulgare
2 Aromatherapy
2 Vitamin B6,pyridoxine
2 Chocolate
2 Echinacea
2 Eurycomanone
2 Genistein (soy isoflavone)
2 Ginkgetin
2 High-Ozonide Oil
2 Huperzine A/Huperzia serrata
2 Isobavachalcone
2 isoflavones
2 Juglone
2 Methylene blue
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Propyl gallate
2 Rauwolfia serpentina/Indian Snakeroot
2 α-Santalol/Sandalwood oil
2 Shankhpushpi
2 Vitamin B1/Thiamine
2 Vitamin B12
2 Folic Acid, Vit B9
2 Vitamin D3
1 Astragalus
1 Citric Acid
1 Ajoene (compound of Garlic)
1 alpha Linolenic acid
1 DTS(dibenzyl trisulphide) from Anamu
1 Artemisinin
1 Aloe anthraquinones
1 beta-glucans
1 Baicalin
1 Biochanin A
1 Cannabidiol
1 Boswellia (frankincense)
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Celastrol
1 Chlorophyllin
1 Choline
1 methotrexate
1 Copper and Cu NanoParticles
1 Deguelin
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet Methionine-Restricted Diet
1 Aspirin
1 eicosapentaenoic acid
1 Fenbendazole
1 Gamma-aminobutyric acid
1 Gambogic Acid
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Ginkgolide B
1 Germacranolide sesquiterpene lactone
1 hydrogen sulfide
1 Helleborus niger extracts – Christmas Rose
1 Oleuropein
1 Indole-3-carbinol
1 Butein
1 Scopoletin
1 Kaempferol
1 Lutein
1 Methyl salicylate / Sweet Birch oil
1 Magnetic Field Rotating
1 Methylsulfonylmethane
1 N-Acetyl-Cysteine
1 nicotinamide adenine dinucleotide
1 Neem
1 Oleocanthal
1 Oregano
1 Phenolic Acids
1 Polyphenols
1 Phosphatidylserine
1 Psoralidin
1 Perilla
1 Gold NanoParticles
1 Sinapic acid
1 Sulfasalazine
1 Sesame seeds and Oil
1 Iron
1 Spermidine
1 Terpinen-4-ol / Tea Tree Oil
1 cetuximab
1 Ginseng
1 Aflavin-3,3′-digallate
1 Vanillic Acid
1 Dichloroacetate
1 probiotics
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page