| Source: |
| Type: type of cell death |
| Situation in which a cell actively pursues a course toward death upon receiving certain stimuli. Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die. |
| 5071- | dietSTF, | Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 8827- | DIM, | Inhibition of breast cancer cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 8843- | DIM, | 3,3′-diindolylmethane induces ferroptosis and inhibits proliferation in non-small-cell lung cancer through the AHR/NRF2/GPX4 axis |
| - | in-vitro, | NSCLC, | NA |
| 8854- | DIM, | Rad, | 3,3′-Diindolylmethane: A Promising Sensitizer of γ-Irradiation |
| - | in-vitro, | BC, | MCF7 |
| 8851- | DIM, | 3,3’-Diindolylmethane and its derivatives: nature-inspired strategies tackling drug resistant tumors by regulation of signal transduction, transcription factors and microRNAs |
| - | Review, | Var, | NA |
| 8850- | DIM, | 3,3'-Diindolylmethane Enhances Tumor Regression After Radiation Through Protecting Normal Cells to Modulate Antitumor Immunity |
| - | vitro+vivo, | BC, | MDA-MB-231 |
| 8845- | DIM, | I3C, | 3,3′-Diindolylmethane and indole-3-carbinol: potential therapeutic molecules for cancer chemoprevention and treatment via regulating cellular signaling pathways |
| - | Review, | Var, | NA |
| 8844- | DIM, | I3C, | Unveiling the Multifaceted Pharmacological Actions of Indole-3-Carbinol and Diindolylmethane: A Comprehensive Review |
| - | Review, | Var, | NA | - | Review, | AD, | NA | - | Review, | Stroke, | NA |
| 4984- | Dipy, | ATV, | Immediate Utility of Two Approved Agents to Target Both the Metabolic Mevalonate Pathway and Its Restorative Feedback Loop |
| - | in-vitro, | AML, | NA |
| 6730- | Dipy, | ASA, | Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner |
| - | vitro+vivo, | CRC, | NA |
| 6290- | DL, | Induction of apoptosis by d-limonene is mediated by a caspase-dependent mitochondrial death pathway in human leukemia cells |
| - | in-vitro, | AML, | K562 | - | in-vitro, | AML, | HL-60 |
| 6269- | DL, | Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells |
| - | in-vitro, | CRC, | LS174T |
| 6270- | DL, | d-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer |
| - | vitro+vivo, | Lung, | A549 | - | vitro+vivo, | Lung, | H1299 |
| 6271- | DL, | D-limonene rich volatile oil from blood oranges inhibits angiogenesis, metastasis and cell death in human colon cancer cells |
| - | in-vitro, | Colon, | SW480 | - | in-vitro, | Colon, | HT-29 |
| 6274- | DL, | Protective Effect of D-Limonene against Oxidative Stress-Induced Cell Damage in Human Lens Epithelial Cells via the p38 Pathway |
| - | in-vitro, | Nor, | NA |
| 6276- | DL, | Tam, | Combination of tamoxifen and D-limonene enhances therapeutic efficacy in breast cancer cells |
| - | in-vitro, | BC, | MCF7 |
| 6726- | DMSO, | DMSO induces apoptosis in SV40-transformed human keratinocytes, but not in normal keratinocytes |
| - | in-vitro, | Var, | NA |
| 6328- | DRE, | Hydroalcoholic extract of Taraxacum officinale induces apoptosis and autophagy in 4T1 breast cancer cells |
| - | in-vitro, | BC, | 4T1 |
| 6342- | DRE, | Mechanistic Study on the Inhibitory Effect of Dandelion Extract on Breast Cancer Cell Proliferation and Its Induction of Apoptosis |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | Nor, | MCF10 |
| 6343- | DRE, | Dandelion root extract affects ESCC progression via regulating multiple signal pathways |
| - | vitro+vivo, | ESCC, | NA |
| 6348- | DRE, | New prospects in oncotherapy: bioactive compounds from Taraxacum officinale |
| - | Review, | Var, | NA |
| 6349- | DRE, | Dandelion root extract protects NCM460 colonic cells and relieves experimental mouse colitis |
| - | vitro+vivo, | Nor, | NCM460 |
| 6350- | DRE, | Tracking Evidences of Dandelion for the Treatment of Cancer: From Chemical Composition, Bioactivity, Signaling Pathways in Cancer Cells to Perspective Study |
| - | Review, | Var, | NA |
| 6326- | DRE, | MT/VAE, | Taraxacum officinale extract shows antitumor effects on pediatric cancer cells and enhance mistletoe therapy |
| - | in-vitro, | neuroblastoma, | SH-SY5Y |
| 6317- | DRE, | The efficacy of dandelion root extract in inducing apoptosis in drug-resistant human melanoma cells |
| - | in-vitro, | Melanoma, | A375 |
| 6318- | DRE, | Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways |
| - | vitro+vivo, | CRC, | HCT116 | - | NA, | Nor, | NCM460 |
| 6319- | DRE, | Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells |
| - | in-vitro, | AML, | MV411 | - | in-vitro, | AML, | HL-60 |
| 6320- | DRE, | Selective induction of apoptosis and autophagy through treatment with dandelion root extract in human pancreatic cancer cells |
| - | in-vitro, | PC, | Bxpc-3 | - | in-vitro, | PC, | PANC1 |
| 6322- | DRE, | LGE, | Dandelion Root and Lemongrass Extracts Induce Apoptosis, Enhance Chemotherapeutic Efficacy, and Reduce Tumour Xenograft Growth In Vivo in Prostate Cancer |
| - | vitro+vivo, | Pca, | DU145 |
| 6353- | DRE, | Cisplatin, | Insights Into Protective Mechanisms of Dandelion Leaf Extract Against Cisplatin-Induced Nephrotoxicity in Rats: Role of Inhibitory Effect on Inflammatory and Apoptotic Pathways |
| - | in-vivo, | Nor, | NA |
| 6354- | DRE, | Taraxacum officinale L. in leukemia and lymphoma: current knowledge and prospects for horticulture |
| - | Review, | AML, | NA |
| 6365- | DRE, | AN OVERVIEW OF THERAPEUTIC POTENTIALS OF TARAXACUM OFFICINALE (DANDELION): A TRADITIONALLY VALUABLE HERB WITH A REACH HISTORICAL BACKGROUND |
| - | Review, | Var, | NA |
| 6360- | DRE, | Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma |
| - | in-vitro, | ESCC, | KYSE450 | - | in-vitro, | ESCC, | Eca109 |
| 6367- | DRE, | Antioxidant and antimicrobial activities of Dandelion root extract (Taraxacum officinale) and its cytotoxic effect on MDA-MB-231 breast cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 |
| 6363- | DRE, | Therapeutic Potential of Dandelion (Taraxacum officinale) Root Extract in Colon Cancer: A Comprehensive Review |
| - | in-vitro, | CRC, | NA |
| 6743- | DSF, | Disulfiram/Copper Activates ER Stress to Promote Immunogenic Cell Death of Oral Squamous Cell Carcinoma |
| - | in-vitro, | OS, | NA |
| 6744- | DSF, | Disulfiram modulated ROS-MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | T47D |
| 4913- | DSF, | Anticancer effects of disulfiram: a systematic review of in vitro, animal, and human studies |
| - | Review, | Var, | NA |
| 4916- | DSF, | Cu, | The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics |
| - | Review, | Var, | NA |
| 5010- | DSF, | Cu, | Rad, | Disulfiram/Copper Combined with Irradiation Induces Immunogenic Cell Death in Melanoma |
| - | in-vivo, | Melanoma, | B16-F10 |
| 5006- | DSF, | Cu, | Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition |
| - | vitro+vivo, | lymphoma, | NA |
| 4832- | EA, | Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid |
| - | Review, | Var, | NA |
| 1607- | EA, | Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions |
| - | Review, | GC, | NA |
| 1621- | EA, | The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art |
| - | Review, | Var, | NA |
| 1620- | EA, | Rad, | Radiosensitizing effect of ellagic acid on growth of Hepatocellular carcinoma cells: an in vitro study |
| - | in-vitro, | Liver, | HepG2 |
| 1606- | EA, | Ellagic acid inhibits proliferation and induced apoptosis via the Akt signaling pathway in HCT-15 colon adenocarcinoma cells |
| - | in-vitro, | Colon, | HCT15 |
| 1618- | EA, | A comprehensive review on Ellagic acid in breast cancer treatment: From cellular effects to molecular mechanisms of action |
| - | Review, | BC, | NA |
| 6611- | Ech, | Proliferative activity of a blend of Echinacea angustifolia and Echinacea purpurea root extracts in human vein epithelial, HeLa, and QBC-939 cell lines, but not in Beas-2b cell lines |
| - | in-vitro, | Cerv, | HeLa | - | in-vitro, | Nor, | BEAS-2B | - | in-vitro, | Nor, | HUVECs |
| 6606- | Ech, | Cic, | Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis |
| - | in-vitro, | Colon, | Caco-2 | - | in-vitro, | Colon, | HCT116 |
| 6607- | Ech, | Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines |
| - | in-vitro, | PC, | MIA PaCa-2 | - | in-vitro, | CRC, | Colo320 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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