| Source: |
| Type: Proapototic protein |
| BAX is a member of the Bcl-2 gene family. Pro-apoptotic protein that forms heterodimers with anti-apoptotic BCL2 proteins; involved in various cellular activities and regulated by p53; mediates the release of cytochrome c from mitochondria. |
| 2274- | VitK2, | Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop |
| - | in-vitro, | Nor, | SH-SY5Y |
| - | in-vitro, | Oral, | NA | - | in-vitro, | Nor, | HEK293 | - | in-vitro, | Nor, | HaCaT |
| 7921- | VT, | Vitexin's Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches |
| - | in-vitro, | Colon, | Caco-2 |
| 7908- | VT, | Vitexin isolated from Prosopis cineraria leaves induce apoptosis in K-562 leukemia cells via inhibition of the BCR-ABL-Ras-Raf pathway |
| - | in-vitro, | AML, | NA |
| 4886- | ZER, | Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio |
| - | in-vitro, | Liver, | HepG2 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:26 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid