| 3385- | ART/DHA, | Interaction of artemisinin protects the activity of antioxidant enzyme catalase: A biophysical study |
| - | Study, | NA, | NA |
| 3386- | ART/DHA, | Effects of Caffeine-Artemisinin Combination on Liver Function and Oxidative Stress in Selected Organs in 7,12-Dimethylbenzanthracene-Treated Rats |
| - | in-vivo, | Nor, | NA |
| 3387- | ART/DHA, | Ferroptosis: A New Research Direction of Artemisinin and Its Derivatives in Anti-Cancer Treatment |
| - | Review, | Var, | NA |
| 3388- | ART/DHA, | Keap1 Cystenine 151 as a Potential Target for Artemisitene-Induced Nrf2 Activation |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Nor, | GP-293 | - | in-vitro, | BC, | MDA-MB-231 |
| 3389- | ART/DHA, | Emerging mechanisms and applications of ferroptosis in the treatment of resistant cancers |
| - | Review, | Var, | NA |
| 3390- | ART/DHA, | Ferroptosis: The Silver Lining of Cancer Therapy |
| 3345- | ART/DHA, | Dihydroartemisinin-induced unfolded protein response feedback attenuates ferroptosis via PERK/ATF4/HSPA5 pathway in glioma cells |
| - | in-vitro, | GBM, | NA |
| 3391- | ART/DHA, | Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug |
| - | Review, | Var, | NA |
| 3392- | ART/DHA, | Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways |
| - | in-vitro, | Nor, | Hep3B | - | in-vivo, | NA, | NA |
| 3393- | ART/DHA, | Artemisinin-derived artemisitene blocks ROS-mediated NLRP3 inflammasome and alleviates ulcerative colitis |
| - | in-vivo, | Col, | NA |
| 3394- | ART/DHA, | Anticancer activities and mechanisms of heat-clearing and detoxicating traditional Chinese herbal medicine |
| 3395- | ART/DHA, | Artesunate Induces Ferroptosis in Hepatic Stellate Cells and Alleviates Liver Fibrosis via the ROCK1/ATF3 Axis |
| - | in-vitro, | NA, | HSC-T6 |
| 3396- | ART/DHA, | Progress on the study of the anticancer effects of artesunate |
| - | Review, | Var, | NA |
| 3665- | ART/DHA, | Artemisinin B Improves Learning and Memory Impairment in AD Dementia Mice by Suppressing Neuroinflammation |
| - | Review, | AD, | NA |
| 3666- | ART/DHA, | Artemisinin Attenuates Amyloid-Induced Brain Inflammation and Memory Impairments by Modulating TLR4/NF-κB Signaling |
| - | NA, | AD, | NA |
| 3667- | ART/DHA, | Artemisinin improves neurocognitive deficits associated with sepsis by activating the AMPK axis in microglia |
| - | Review, | Sepsis, | NA |
| 573- | ART/DHA, | Artesunate suppresses tumor growth and induces apoptosis through the modulation of multiple oncogenic cascades in a chronic myeloid leukemia xenograft mouse model |
| - | vitro+vivo, | NA, | NA |
| 576- | ART/DHA, | Profiling of Multiple Targets of Artemisinin Activated by Hemin in Cancer Cell Proteome |
| - | Analysis, | NA, | NA |
| 575- | ART/DHA, | Dihydroartemisinin initiates ferroptosis in glioblastoma through GPX4 inhibition |
| - | in-vitro, | GBM, | U87MG |
| 574- | ART/DHA, | Dihydroartemisinin suppresses glioma proliferation and invasion via inhibition of the ADAM17 pathway |
| 572- | ART/DHA, | High-throughput screening identifies artesunate as selective inhibitor of cancer stemness: Involvement of mitochondrial metabolism |
| 571- | ART/DHA, | TMZ, | Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence |
| - | vitro+vivo, | GBM, | A172 | - | vitro+vivo, | GBM, | U87MG |
| 570- | ART/DHA, | Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/β-catenin signaling |
| - | vitro+vivo, | NSCLC, | A549 | - | vitro+vivo, | NSCLC, | H1299 |
| 561- | ART/DHA, | Antitumor and immunomodulatory properties of artemether and its ability to reduce CD4+ CD25+ FoxP3+ T reg cells in vivo |
| - | in-vivo, | NA, | NA |
| 556- | ART/DHA, | Artemisinins as a novel anti-cancer therapy: Targeting a global cancer pandemic through drug repurposing |
| - | Review, | NA, | NA |
| 557- | ART/DHA, | Artemisinin and Its Derivatives in Cancer Care |
| - | Review, | Var, | NA |
| 555- | ART/DHA, | Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action |
| - | Review, | NA, | NA |
| 558- | ART/DHA, | Artemisinin and Its Synthetic Derivatives as a Possible Therapy for Cancer |
| - | Review, | NA, | NA |
| 559- | ART/DHA, | Artemisinin and its derivatives: a promising cancer therapy |
| - | Review, | NA, | NA |
| 560- | ART/DHA, | Dihydroartemisinin shift the immune response towards Th1, inhibit the tumor growth in vitro and in vivo |
| - | in-vivo, | NA, | NA |
| 562- | ART/DHA, | Artesunate exerts an anti-immunosuppressive effect on cervical cancer by inhibiting PGE2 production and Foxp3 expression |
| - | in-vivo, | NA, | HeLa |
| 563- | ART/DHA, | Artesunate down-regulates immunosuppression from colorectal cancer Colon26 and RKO cells in vitro by decreasing transforming growth factor β1 and interleukin-10 |
| - | in-vitro, | Colon, | colon26 | - | in-vitro, | CRC, | RKO |
| 564- | ART/DHA, | Cisplatin, | Dihydroartemisinin as a Putative STAT3 Inhibitor, Suppresses the Growth of Head and Neck Squamous Cell Carcinoma by Targeting Jak2/STAT3 Signaling |
| - | in-vitro, | NA, | HN30 |
| 565- | ART/DHA, | Artesunate as an Anti-Cancer Agent Targets Stat-3 and Favorably Suppresses Hepatocellular Carcinoma |
| 566- | ART/DHA, | 2DG, | Dihydroartemisinin inhibits glucose uptake and cooperates with glycolysis inhibitor to induce apoptosis in non-small cell lung carcinoma cells |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | PC9 |
| 569- | ART/DHA, | Dihydroartemisinin exhibits anti-glioma stem cell activity through inhibiting p-AKT and activating caspase-3 |
| - | in-vitro, | GBM, | NA |
| 567- | ART/DHA, | An Untargeted Proteomics and Systems-based Mechanistic Investigation of Artesunate in Human Bronchial Epithelial Cells |
| - | in-vitro, | Lung, | BEAS-2B |
| 568- | ART/DHA, | Mechanism-Guided Design and Synthesis of a Mitochondria-Targeting Artemisinin Analogue with Enhanced Anticancer Activity |
| - | in-vitro, | NA, | MDA-MB-231 | - | in-vitro, | NA, | HeLa | - | in-vitro, | NA, | SkBr3 | - | in-vitro, | NA, | HCT116 |
| 1076- | ART/DHA, | The Potential Mechanisms by which Artemisinin and Its Derivatives Induce Ferroptosis in the Treatment of Cancer |
| - | Review, | NA, | NA |
| 1079- | ART/DHA, | Artesunate inhibits the growth and induces apoptosis of human gastric cancer cells by downregulating COX-2 |
| - | in-vitro, | GC, | BGC-823 | - | in-vitro, | GC, | HGC27 | - | in-vitro, | GC, | MGC803 |
| 1099- | ART/DHA, | Dihydroartemisinin inhibits IL-6-induced epithelial–mesenchymal transition in laryngeal squamous cell carcinoma via the miR-130b-3p/STAT3/β-catenin signaling pathway |
| - | in-vitro, | NA, | NA |
| 1075- | ART/DHA, | Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF-β signaling in breast cancer |
| - | in-vitro, | Nor, | L929 |
| 1074- | ART/DHA, | Artemisinin attenuates lipopolysaccharide-stimulated proinflammatory responses by inhibiting NF-κB pathway in microglia cells |
| - | in-vitro, | Nor, | BV2 |
| 1026- | ART/DHA, | Artemisinin improves the efficiency of anti-PD-L1 therapy in T-cell lymphoma |
| 957- | ART/DHA, | Artemisinin inhibits the development of esophageal cancer by targeting HIF-1α to reduce glycolysis levels |
| - | in-vitro, | ESCC, | KYSE150 | - | in-vitro, | ESCC, | KYSE170 |
| 976- | ART/DHA, | Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells |
| - | in-vitro, | BC, | MCF-7 |
| 985- | ART/DHA, | Artemisinin suppresses aerobic glycolysis in thyroid cancer cells by downregulating HIF-1a, which is increased by the XIST/miR-93/HIF-1a pathway |
| - | in-vitro, | Thyroid, | TPC-1 | - | Human, | NA, | NA |
| 5381- | ART/DHA, | Artemisitene triggers calcium-dependent ferroptosis by disrupting the LSH-EWSR1 interaction in colorectal cancer |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Nor, | NCM460 | - | in-vitro, | CRC, | HT29 | - | in-vitro, | CRC, | HCT8 |
| 5383- | ART/DHA, | Artesunate is a drug used to treat severe malaria. |
| - | Review, | Var, | NA |
| 5382- | ART/DHA, | A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies |
| - | Trial, | Var, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid