| Source: |
| Type: |
| Drug dosage vs efficacy, and actual dosage number of research papers. |
| 8295- | lign, | Distribution, biosynthesis and therapeutic potential of lignans |
| - | Review, | Var, | NA |
| 8314- | lign, | Reduction in Ki-67 in Benign Breast Tissue of High Risk Women with the Lignan Secoisolariciresinol Diglycoside (SDG) |
| - | Trial, | BC, | NA |
| 8296- | lign, | Metabolism of secoisolariciresinol-diglycoside the dietary precursor to the intestinally derived lignan enterolactone in humans |
| - | Trial, | Nor, | NA |
| 8312- | lign, | Influence of Flaxseed Lignan Supplementation to Older Adults on Biochemical and Functional Outcome Measures of Inflammation |
| - | Trial, | Nor, | NA |
| 8297- | lign, | Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside |
| - | Trial, | Nor, | NA |
| 8299- | lign, | Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer |
| - | Trial, | BC, | NA |
| 8329- | LIN, | Microglial-targeting induced by intranasal linalool during neurological protection postischemia |
| - | in-vivo, | Stroke, | NA | - | in-vivo, | AD, | NA |
| 8326- | LIN, | Linalool in cancer pharmacology: pharmacokinetic limitations and preclinical cytotoxic evidence for translational development |
| - | Review, | Var, | NA |
| 8320- | LIN, | Ameliorative Effect of Linalool in Cisplatin-Induced Nephrotoxicity: The Role of HMGB1/TLR4/NF-κB and Nrf2/HO1 Pathways |
| - | in-vivo, | Nor, | NA |
| 8380- | LT, | Luteolin, a bioactive compound from Celastrus orbiculatus stem, inhibits cervical cancer via CA2 suppression: A translational study bridging basic research and clinical application |
| - | Trial, | Cerv, | NA |
| 8406- | LT, | Cisplatin, | Luteolin sensitizes the anticancer effect of cisplatin via c-Jun NH2-terminal kinase–mediated p53 phosphorylation and stabilization |
| - | vitro+vivo, | Liver, | HepG2 | - | in-vitro, | Laryn, | HEp2 |
| 8366- | LT, | Preliminary Evidence on Safety and Clinical Efficacy of Luteolin for Patients With Prostate Cancer Under Active Surveillance |
| - | Trial, | Pca, | NA |
| 8371- | LT, | Study on the regulatory mechanism of luteolin inhibiting WDR72 on the proliferation and metastasis of non small cell lung cancer |
| - | vitro+vivo, | Lung, | A549 | - | in-vitro, | Lung, | H1299 | - | in-vitro, | Nor, | BEAS-2B |
| 2906- | LT, | Luteolin, a flavonoid with potentials for cancer prevention and therapy |
| - | Review, | Var, | NA |
| - | in-vitro, | Nor, | MCF10 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-468 | - | in-vitro, | PC, | Bxpc-3 |
| 8345- | Lut, | Lutein inhibits breast cancer cell growth by suppressing antioxidant and cell survival signals and induces apoptosis |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 8357- | Lut, | Comparison of lutein bioavailability from vegetables and supplement |
| - | Study, | Nor, | NA |
| 8351- | Lut, | Zeax, | Lutein and Zeaxanthin Influence Brain Function in Older Adults: A Randomized Controlled Trial |
| - | Trial, | AD, | NA |
| 8352- | Lut, | Zeax, | The effects of lutein and zeaxanthin on resting state functional connectivity in older Caucasian adults: a randomized controlled trial |
| - | Trial, | AD, | NA |
| 8353- | Lut, | Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial |
| - | Trial, | AD, | NA |
| 8355- | Lut, | Zeax, | Oral Antioxidant and Lutein/Zeaxanthin Supplements Slow Geographic Atrophy Progression to the Fovea in Age-Related Macular Degeneration |
| - | Trial, | AMD, | NA |
| 8356- | Lut, | Amount of fat in the diet affects bioavailability of lutein esters but not of alpha-carotene, beta-carotene, and vitamin E in humans |
| - | Trial, | Nor, | NA |
| 3268- | Lyco, | Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders |
| - | Review, | AD, | NA |
| 3277- | Lyco, | Recent trends and advances in the epidemiology, synergism, and delivery system of lycopene as an anti-cancer agent |
| - | Review, | Var, | NA |
| 1711- | Lyco, | Nutritional Importance of Carotenoids and Their Effect on Liver Health: A Review |
| - | Review, | Var, | NA |
| 1713- | Lyco, | Lycopene: A Potent Antioxidant with Multiple Health Benefits |
| - | Review, | Nor, | NA |
| 1716- | Lyco, | Anti-inflammatory Activity of β-Carotene, Lycopene and Tri-n-butylborane, a Scavenger of Reactive Oxygen Species |
| - | in-vitro, | AML, | RAW264.7 |
| 7742- | Lyco, | isoFl, | Lycopene and soy isoflavones in the treatment of prostate cancer |
| - | Trial, | Pca, | NA |
| 8423- | Lyco, | Rad, | Tomato Juice Consumption Could Improve Breast Skin Adverse Effects of Radiotherapy in Breast Cancer Patients |
| - | Trial, | BC, | NA |
| 8422- | Lyco, | Rad, | Dietary and Serum Lycopene Levels in Prostate Cancer Patients Undergoing Intensity-Modulated Radiation Therapy |
| - | Trial, | Pca, | NA |
| 8420- | Lyco, | Anticancer activity of lycopene in HT-29 colon cancer cell line |
| - | in-vitro, | CRC, | HT-29 |
| 8418- | Lyco, | docx, | A phase I study of docetaxel plus synthetic lycopene in metastatic prostate cancer patients |
| - | Trial, | Pca, | NA |
| 8416- | Lyco, | Lycopene alleviates cognitive dysfunctions in an Alzheimer's disease rat model via suppressing the oxidative and neuroinflammatory signaling |
| - | in-vivo, | AD, | NA |
| - | Review, | Var, | NA |
| 8408- | Lyco, | Enhanced bioavailability of lycopene when consumed as cis-isomers from tangerine compared to red tomato juice, a randomized, cross-over clinical trial |
| - | Trial, | Nor, | NA |
| - | in-vivo, | BPH, | NA |
| 4784- | Lyco, | Protective effects of lycopene in cancer, cardiovascular, and neurodegenerative diseases: An update on epidemiological and mechanistic perspectives |
| - | Review, | Diabetic, | NA | - | Review, | CardioV, | NA |
| 4788- | Lyco, | Lycopene as a potential anticancer agent: Current evidence on synergism, drug delivery systems and epidemiology (Review) |
| - | Review, | Var, | NA |
| 8727- | M-Blu, | High absolute bioavailability of methylene blue given as an aqueous oral formulation |
| - | Trial, | Nor, | NA |
| 8728- | M-Blu, | Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue |
| - | Review, | AD, | NA |
| 8732- | M-Blu, | Methylene blue for intractable pain from oral mucositis related to cancer treatment: a randomized phase 2 clinical trial |
| - | Trial, | Var, | NA |
| 8735- | M-Blu, | PDT, | Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | Nor, | MCF10 |
| 8495- | MAG, | Pharmacokinetics, bioavailability, and tissue distribution of magnolol following single and repeated dosing of magnolol to rats |
| - | in-vivo, | Nor, | NA |
| 8503- | MAG, | Magnolol mitigates neuroinflammation via NF-κB/IL-6/IL-1β pathways in AlCl₃-induced Alzheimer's disease: insights from in-vivo and in-silico investigations |
| - | in-vivo, | AD, | NA |
| 8513- | MAG, | Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I |
| - | vitro+vivo, | Oral, | SCC4 | - | in-vitro, | Tong, | SCC9 | - | in-vitro, | SCC, | CAL27 |
| 8507- | MAG, | Magnolol acts as a neurorestorative agent in an Aβ1‑42‑induced mouse model of Alzheimer's disease |
| - | in-vivo, | AD, | NA |
| 8561- | Matr, | Matrine triggers colon cancer cell apoptosis and G0/G1 cell cycle arrest via mediation of microRNA-22 |
| - | in-vitro, | Colon, | SW480 | - | in-vitro, | CRC, | SW-620 |
| 8566- | Matr, | Matrine suppresses lung metastasis of human hepatocellular carcinoma by directly targeting matrix metalloproteinase-9 |
| - | vitro+vivo, | HCC, | MHCC-97H |
| 8571- | Matr, | Effect of Matrine on HPAC cell migration by down-regulating the expression of MT1-MMP via Wnt signaling |
| - | in-vitro, | PC, | Capan1 |
| 8572- | Matr, | Matrine induces mitochondrial apoptosis in cisplatin-resistant non-small cell lung cancer cells via suppression of β-catenin/survivin signaling |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H460 |
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1114 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid