eff Cancer Research Results

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Source:
Type:
Power to enhance an anti cancer effect
Scientific Papers found: Click to Expand⟱
7577- HPT,  Rad,    Randomized trial of hyperthermia and radiation for superficial tumors
- Trial, Var, NA
RadioS↑, eff↑, Dose↝,
7571- HPT,    Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition
- vitro+vivo, Var, NA
BRCA2↓, eff↑, RadioS↑,
7626- HPT,  Rad,    Dynamics of chromosomal aberrations, induction of apoptosis, BRCA2 degradation and sensitization to radiation by hyperthermia
- in-vitro, Var, NA
BRCA2↓, selectivity↑, RadioS↑, eff↝,
7623- HPT,  Rad,    Enhancing radiosensitisation of BRCA2-proficient and BRCA2-deficient cell lines with hyperthermia and PARP1-i
- Review, Var, NA
BRCA2↓, RadioS↑, eff↑,
5054- HPT,    Induction of Oxidative Stress by Hyperthermia and Enhancement of Hyperthermia-Induced Apoptosis by Oxidative Stress Modification
- Review, Var, NA
eff↓, ROS↑, Apoptosis↑,
7542- HT,    Hydroxytyrosol Induces Apoptosis and Cell Cycle Arrest and Suppresses Multiple Oncogenic Signaling Pathways in Prostate Cancer Cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, C4-2B - in-vitro, Nor, RWPE-1
TumCP↓, selectivity↑, TumCCA↑, cycD1/CCND1↓, CDK2↓, CDK4↓, Apoptosis↑, Casp↑, cl‑PARP↑, Bax:Bcl2↑, tumCV↓, Akt↓, STAT3↓, NF-kB↓, AR↓, ROS↑, mtDam↑, BioAv↓, toxicity↓, eff↑,
7540- HT,    Discovery of hydroxytyrosol as thioredoxin reductase 1 inhibitor to induce apoptosis and G1/S cell cycle arrest in human colorectal cancer cells via ROS generation
- in-vitro, CRC, HCT8 - in-vitro, CRC, HCT116
TrxR1↑, ROS↑, TumCP↓, Apoptosis↑, TumCCA↑, Dose↝, eff↓,
4641- HT,    Hydroxytyrosol induced ferroptosis through Nrf2 signaling pathway in colorectal cancer cells
- in-vitro, CRC, HCT116 - in-vitro, CRC, SW48
Ferroptosis↑, Iron↑, lipid-P↑, ROS↑, GSH↓, MMP↓, GPx4↓, TLR1↑, eff↓, NRF2↓, ROS↑,
7479- Hup,    A phase II trial of huperzine A in mild to moderate Alzheimer disease
- Trial, AD, NA
*Dose↝, *cognitive↑, *eff∅, *AChE↓,
7567- HYP,    Hyperoside: A review on its sources, biological activities, and molecular mechanisms
- Review, Var, NA
*AntiCan↑, *Bacteria↓, *AntiViral↑, *antiD↓, *RenoP↑, *hepatoP↑, *eff↑, *Sepsis↓, *AntiArt↑, *Stroke↓, TumCMig↓, TumCI↓, MTA1↓, TIMP2↓, MMP2↓, MMP↓, Cyt‑c↑, Akt↓, mTOR↓, P70S6K↓, TumAuto↑, PD-L1↓, TNF-α↓, IL1β↓, IL6↓, IL8↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Bak↑, VEGF↓, Casp3↑, Casp8↑, P53↑, GSH↓, SOD↓, Catalase↓, TAC↓, XIAP↓, ROS↓, NF-kB↓, TLR4↓, P-gp/ABCB1↓, LRP1↓, Fas↑, p27/CDKN1B↑, *cardioP↑, *AntiThr↑, *PAI-1/SERPINE1↓, *BUN↓, *ALAT↓, *AST↓, *neuroP?,
7558- HYP,    The Cytoprotective Effect of Hyperoside against Oxidative Stress Is Mediated by the Nrf2-ARE Signaling Pathway through GSK-3β Inactivation
- in-vivo, AD, NA
*ROS↓, *NRF2↑, *ARE↑, *HO-1↑, *GSK‐3β↑, *Keap1↓, *eff↑,
7588- I3C,    Indole-3-carbinol suppresses NF-κB activity and stimulates the p53 pathway in pre-B acute lymphoblastic leukemia cells
- in-vitro, AML, NA
TumCG↓, TumCCA↑, Apoptosis↑, P53↑, P21↑, BAX↑, PUMA↑, NOXA↑, APAF1↑, NF-kB↓, IAP1↓, Bcl-xL↓, Bcl-2↓, XIAP↓, Myc↓, ChemoSen↑, Casp9↑, cl‑PARP↑, eff↑,
7768- IBC,    Isobavachalcone Induces ROS-Mediated Apoptosis via Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC-3 Cells
- in-vitro, Pca, PC3
NA↑, TrxR1↓, ER Stress↑, TumCP↓, Apoptosis↑, GRP78/BiP↑, ATF4↑, XBP-1↑, CHOP/DDIT3↑, p‑eIF2α↑, eff↓, cl‑Casp3↑,
7802- IBC,    Isobavachalcone disrupts mitochondrial respiration and induces cytotoxicity through ROS accumulation and Akt suppression
- in-vitro, Liver, HepG2
TumCD↑, Apoptosis↑, ROS↑, mtDam↑, p‑Akt↓, eff↓,
7772- IBC,    Isobavachalcone inhibits acute myeloid leukemia: Potential role for ROS-dependent mitochondrial apoptosis and differentiation
- vitro+vivo, AML, NA
Apoptosis↑, Diff↑, tumCV↓, TumCP↓, MMP↓, BAX↑, Bcl-2↓, Bcl-xL↓, Mcl-1↓, Cyt‑c↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, p‑MEK↑, p‑ERK↑, ROS↑, eff↓,
7776- IBC,    Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation
- vitro+vivo, PC, Panc02
TumCP↓, Apoptosis↑, ROS↑, TumW↓, CD8+↑, M2 MC↓, CSCs↓, antiNeop↑, Imm↑, eff↓, Bcl-2↓, BAX↑,
7674- iod,    Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway
- in-vitro, BC, NA
AntiTum↑, selectivity↑, MMP↓, antiOx↑, Thiols↓, Bcl-2↓, BAX↑, eff↓, Casp↑, ROS↓, ROS↑, Cyt‑c↑, AIF↑,
7678- iod,    Signaling pathways involved in the antiproliferative effect of molecular iodine in normal and tumoral breast cells: evidence that 6-iodolactone mediates apoptotic effects
- in-vitro, Nor, MCF12A - in-vitro, BC, MCF7
TumCCA↑, selectivity↑, 6IL↑, eff↑,
7684- iod,    Molecular iodine impairs chemotherapy resistance and adverse effects in breast cancer treatments
- Trial, BC, NA
Dose↝, OS↑, antiNeop↑, eff↑,
7659- IP,    Inulin-type fructans and reduction in colon cancer risk: review of experimental and human data
- in-vivo, Colon, NA
GutMicro↑, SCFAs↑, eff↑, Buty↑, Risk↓,
7663- IP,    Industrial additive and dietary fiber inulin induces tumor-selective necrotic death via mitochondrial lipid peroxidation involving MYC and YAP
- in-vivo, Var, NA
GutMicro↑, lipid-P↑, mtDam↑, eff↑, Myc↓, YAP/TEAD↓, AR↑,
7669- IP,    Colorectal cancer and inulin supplementation: the good, the bad, and the unhelpful
- Review, CRC, NA
GutMicro↑, Buty↑, eff↓, Inflam↑, eff∅, SCFAs↑,
7724- IP6,    Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFkappaB-mediated cell survival pathway
- in-vitro, Cerv, HeLa
NF-kB↓, Akt↓, MMP↓, Cyt‑c↑, Apoptosis↑, Casp3↑, Casp9↑, PARP↑, eff↑,
7644- IP6,  MS-275,    Apoptotic effect of IP6 was not enhanced by co-treatment with myo-inositol in prostate carcinoma PC3 cells
- in-vitro, Pca, PC3
Casp3↑, eff∅,
7700- IP6,    A84 THE USE OF PHYTASE TO ENHANCE DIETARY IRON AND ZINC ABSORPTION - A SCOPING REVIEW
- Review, Nor, NA
*Iron↓, *eff↑,
7747- ISL,    Isoliquiritigenin Induces Apoptosis via ROS-Mediated Inhibition of p38/mTOR/STAT3 Pathway in Human Melanoma Cells
- in-vitro, Melanoma, SK-MEL-28
*Inflam↓, *AntiViral↑, *AntiTum↑, *antiOx↑, cl‑Casp9↑, cl‑Casp7↑, cl‑Casp3↑, cl‑PARP↑, BAX↑, Bcl-2↓, Cyt‑c↑, cycD1/CCND1↓, cycD1/CCND1↓, survivin↓, ROS↓, eff↓, p‑mTOR↓, p‑STAT3↓, p‑MAPK↓,
7758- ISL,    Targeting the JAK/STAT pathway with isoliquiritigenin in ovarian cancer: molecular mechanisms and therapeutic implications
- Review, Ovarian, NA
JAK↓, STAT↓, toxicity↓, *antiOx↑, *ROS↓, *NRF2↑, *ARE↑, *HO-1↑, *NQO1↑, *Inflam↓, *NF-kB↓, *MAPK↓, *SOD↑, *Catalase↑, *GPx↑, *AntiViral↑, *NADPH↑, ROS↓, p38↓, mTOR↓, STAT3↓, cycD1/CCND1↓, survivin↓, p38↑, MAPK↑, mtDam↑, ER Stress↑, ROS↑, Apoptosis↑, GLUT4↓, ATP↓, Glycolysis↓, eff↑,
7761- ISL,    Targeting digestive system cancers with isoliquiritigenin: a comprehensive review of antitumor mechanisms
- Review, Var, NA
Apoptosis↑, TumAuto↑, TumCCA↑, ROS↑, JNK↑, p38↑, STAT3↑, NF-kB↓, IκB↑, Bcl-2↓, BAX↑, cl‑Casp3↑, cl‑PARP↑, P21↑, p27/CDKN1B↑, CycB/CCNB1↑, CDK1↓, CDK2↓, GRP78/BiP↓, PI3K↓, Akt↓, mTOR↓, eff↑, GLUT4↓, lactateProd↓, OXPHOS↓, Glycolysis↓, BioAv↑, ENO1↓, ALDOA↓, LDHA↓, MCT4↓, RadioS↑, Ferroptosis↑, i-Iron↑, BioAv↑, Half-Life↓,
8280- ISL,    ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro
- vitro+vivo, HCC, SMMC-7721 cell
tumCV↓, TumCP↓, Apoptosis↑, TumAuto↑, PI3K↓, Akt↓, mTOR↓, TumCG↓, LC3II↑, cl‑Casp3↑, eff↑,
7737- isoFl,    An updated review of dietary isoflavones: Nutrition, processing, bioavailability and impacts on human health
- Review, Nor, NA
*cardioP↑, Risk↓, *BMD↑, *eff↑, *antiOx↑, *lipid-P↓, *LDL↓, AntiThr↑, AntiAg↑, PSA↓, TumCCA↑, cognitive↑, memory↑,
7732- isoFl,    Biological activities and therapeutic potential of soy isoflavones: a focus on anticancer activity
- Review, Var, NA
*Inflam↓, *ROS↓, Apoptosis↑, NOS2↑, *Aβ↓, *BioAv↓, *BioAv↑, *BioAv↝, *neuroP↑, *BBB↑, TNF-α↓, ROS↑, selectivity↑, ChemoSen↑, eff↝,
7882- isoO,    Isoorientin triggers apoptosis of hepatoblastoma by inducing DNA double-strand breaks and suppressing homologous recombination repair
- in-vitro, Liver, NA
TumCP↓, ATM↓, eff↑,
7856- isoO,    Isoorientin induces the apoptosis and cell cycle arrest of A549 human lung cancer cells via the ROS‑regulated MAPK, STAT3 and NF‑κB signaling pathways
- in-vitro, Lung, A549
Bacteria↓, Inflam↓, TumCD↑, selectivity↑, Apoptosis↑, MMP↓, BAX↑, cl‑Casp3↑, PARP↓, Bcl-2↓, TumCCA↑, CycB/CCNB1↓, CDK1↓, CDK2↓, NA↑, p27/CDKN1B↑, ROS↑, eff↓, p‑p38↑, p‑JNK↑, ERK↓, STAT3↓, NF-kB↓,
7855- isoO,    Isoorientin induces apoptosis and autophagy simultaneously by reactive oxygen species (ROS)-related p53, PI3K/Akt, JNK, and p38 signaling pathways in HepG2 cancer cells
- in-vitro, Liver, HepG2 - in-vitro, Nor, HL7702
TumAuto↑, Beclin-1/ATG6↑, LC3II↑, eff↓, ROS↑, Fas↑, P53↓, PI3K↓, Akt↓, NF-kB↓, Cyt‑c↑, Casp3↑, cl‑PARP↑,
7854- isoO,    Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells
- in-vitro, Liver, HepG2
TumCD↑, selectivity↑, *toxicity↓, cl‑PARP↑, DNAdam↑, Bax:Bcl2↑, MMP↓, Cyt‑c↑, Casp3↑, ROS↑, NO↑, p‑Akt↓, FOXO4↑, eff↓,
7866- isoO,    Orientin and Cancer Suppression: Molecular Mechanisms and Synergistic Effects
- Review, Var, NA
TumCP↓, Apoptosis↑, angioG↓, TumMeta↓, selectivity↑, *toxicity↓, Bax:Bcl2↑, Cyt‑c↑, Diablo↑, Casp9↑, Casp3↑, cl‑PARP↑, DNAdam↑, γH2AX↑, ROS↑, PCNA↓, MMP2↓, MMP9↓, TumCCA↑, cycD1/CCND1↓, CDK4↓, P21↑, NF-kB↓, HH↓, Ki-67↓, COX2/PTGS2↓, TNF-α↓, ChemoSen↑, chemoP↑, eff↑, angioG↓,
7812- ISQ,    Isoquercitrin promotes ferroptosis and oxidative stress in nasopharyngeal carcinoma via the AMPK/NF-κB pathway
- vitro+vivo, NPC, CNE1 - in-vitro, NPC, HNE1
tumCV↓, TumCP↓, ROS↑, lipid-P↑, NF-kB↓, MAPK↓, IL1β↓, TumCG↓, lipid-P↓, Ferroptosis↓, eff↓,
7810- ISQ,    Isoquercitrin Inhibits Lung Cancer Cell Growth Through Triggering Pyroptosis and Ferroptosis
- vitro+vivo, Lung, A549 - in-vitro, Nor, BEAS-2B
tumCV↓, selectivity↑, Apoptosis↑, NLRP3↑, Pyro↑, Ferroptosis↑, ROS↑, eff↓, Dose↝, TumCG↓,
7797- ISQ,    Isoquercitrin Suppresses Esophageal Squamous Cell Carcinoma (ESCC) by Inducing Excessive Autophagy and Promoting Apoptosis via the AKT/mTOR Signaling Pathway
- vitro+vivo, ESCC, KYSE-510 - in-vitro, ESCC, KYSE450
TumCG↓, Apoptosis↓, Casp↑, Bcl-2↓, EMT↓, TumAuto↑, ROS↑, Akt↓, PI3K↓, Catalase↓, SOD1↓, SOD2↓, eff↓,
7841- ISQ,    Enzymatically modified isoquercitrin improves endothelial function in volunteers at risk of cardiovascular disease
- Human, CardioV, NA
*Risk↓, *BioAv↑, *Dose↝, *eff↑,
7836- ISQ,    An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease
- in-vivo, AD, NA
*AChE↓, *Aβ↓, *BBB↑, *Ach↑, *cognitive↑, *APP↓, *tau↓, *eff↑,
7848- ISQ,    Review of anticancer mechanisms of isoquercitin
- Review, Var, NA
BioAv↑, eff↑, *antiOx↓, TumCP↓, *Inflam↓, *AntiDiabetic↑, lipid-P↓, *toxicity↓, *Half-Life↝, *Half-Life↑, *XO↝, *IronCh↝, *VitC↑, *ROS↓, β-catenin/ZEB1↓, Casp3↑, Casp8↑, Casp9↑, MMP↓, p‑ERK↓, p‑cJun↑,
7996- itraC,    Itraconazole in the Treatment of Aberrantly Active Hedgehog and/or PI3K Recurrent Ovarian Cancer
- Trial, Ovarian, NA
HH↓, PI3K↓, toxicity↝, eff∅, CA125∅, other↝,
8011- itraC,    Anti-proliferation of breast cancer cells with itraconazole: Hedgehog pathway inhibition induces apoptosis and autophagic cell death
- vitro+vivo, BC, MCF7 - vitro+vivo, BC, SkBr3
MMP↓, Bcl-2↓, Casp3↑, TumAuto↑, LC3II↑, p62↓, HH↓, Shh↓, Gli1↓, Apoptosis↑, TumVol↓, eff↑, TumCCA↑,
8033- IVM,  dietMet,  rMETase,    Direct comparison of efficacy of combining ivermectin versus five first-line chemotherapy drugs with recombinant methioninase against colon-cancer cells
- in-vitro, CRC, HCT116
eff↑, ChemoSen↑, Synergy↑, selectivity↑, Synergy↑, TumCCA↑,
8028- IVM,    Ivermectin as an Alternative Anticancer Agent: A Review of Its Chemical Properties and Therapeutic Potential
- Review, Var, NA
*BioAv↝, Apoptosis↑, TumCP↓, Wnt↓, β-catenin/ZEB1↓, TumCG↓, TumMeta↓, PI3K↓, Akt↓, mTOR↓, TumPF↓, CSCs↓, eff↑, ChemoSen↑, mtDam↑, MMP↓, ATP↓, ROS↑, NF-kB↓, BAX↑, Casp3↑, Casp9↑, ICD↑, Ki-67↓, PSA↓, YAP/TEAD↓,
8027- IVM,    Progress in Understanding the Molecular Mechanisms Underlying the Antitumour Effects of Ivermectin
- Review, Var, NA
*AntiP↑, TumCD↑, PAK1↑, TumAuto↑, Casp↑, ICD↑, TCF↝, Hippo↓, Akt↓, mTOR↓, angioG↓, CSCs↓, MMP↓, Cyt‑c↑, Apoptosis↑, BAX↑, P53↑, Bcl-2↓, cycE/CCNE↓, cycD1/CCND1↓, CDK2↓, CDK6↓, CDK4↓, YAP/TEAD↓, TFE3↑, mTORC1↓, mitResp↓, OCR↓, compI↓, MMP↓, ROS↑, SOD2↑, ATP↓, eff↓, mitA↓, P-gp/ABCB1↓, TumVol↓,
8025- IVM,    Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth
- in-vitro, CRC, SW480 - in-vivo, CRC, HCT116
*AntiP↓, *Inflam↓, *AntiViral↑, AntiTum↑, TumCP↓, Apoptosis↑, Casp3↑, Casp7↑, BAX↑, cl‑PARP↑, Bcl-2↓, mt-ROS↑, eff↓, Dose↝, TumCCA↑,
8024- IVM,    Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway
- vitro+vivo, ESCC, KYSE-30 - in-vitro, ESCC, NE3
TumCP↓, mtDam↑, Apoptosis↑, ROS↑, NF-kB↓, Bax:Bcl2↑, LDH↝, TumCCA↑, cl‑Casp9↑, cl‑Casp3↑, cl‑PARP↑, eff↓,
8022- IVM,    Antibiotic ivermectin preferentially targets renal cancer through inducing mitochondrial dysfunction and oxidative damage
- vitro+vivo, RCC, NA
AntiP↑, TumCP↓, Apoptosis↑, selectivity↑, TumCG↓, MMP↓, mitResp↓, ATP↓, ROS↑, eff↓,

Showing Research Papers: 801 to 850 of 1416
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1416

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 21,   ARE/EpRE↑, 1,   Catalase↓, 12,   Catalase↑, 4,   Catalase∅, 1,   Copper↓, 1,   CoQ10↑, 1,   cystine↓, 1,   DJ-1↓, 1,   ENOX2↓, 2,   ENOX2↑, 1,   Fenton↑, 16,   GCLM↓, 1,   GPx↓, 8,   GPx↑, 5,   GPx1↓, 1,   GPx1↑, 1,   GPx4↓, 16,   GSH↓, 74,   GSH↑, 3,   GSH↝, 1,   GSH∅, 1,   i-GSH∅, 1,   mt-GSH↓, 1,   GSH/GSSG↓, 12,   GSR↓, 3,   GSSG↓, 1,   ox-GSSG↑, 1,   GSTs↓, 2,   GSTs↑, 2,   GSTs∅, 1,   H2O2?, 1,   H2O2↑, 17,   e-H2O2↓, 1,   i-H2O2↑, 1,   i-H2O2∅, 1,   mt-H2O2↑, 1,   HO-1↓, 8,   HO-1↑, 14,   HO-2↓, 1,   HO-2↑, 1,   hyperG↓, 1,   Iron↓, 1,   Iron↑, 11,   Iron↝, 2,   i-Iron↑, 2,   c-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 4,   lipid-P↑, 40,   MDA↓, 3,   MDA↑, 11,   MPO↓, 1,   NADH↑, 1,   NADHdeh?, 1,   NADPH/NADP+↓, 1,   NQO1↓, 2,   NQO1↑, 1,   Nrf1↑, 2,   NRF2↓, 17,   NRF2↑, 20,   NRF2↝, 3,   p‑NRF2↑, 1,   Prx↓, 1,   Prx3↑, 1,   Prx4↑, 1,   Prx6↑, 2,   PrxII↓, 1,   PYCR1↓, 1,   RNS↑, 2,   ROS?, 5,   ROS↓, 23,   ROS↑, 554,   ROS⇅, 7,   ROS↝, 5,   ROS∅, 1,   i-ROS↓, 1,   i-ROS↑, 6,   mt-ROS↑, 18,   RPM↑, 1,   SOD↓, 18,   SOD↑, 6,   mt-SOD↑, 1,   SOD1↓, 3,   SOD1↑, 2,   SOD2↓, 5,   SOD2↑, 4,   TAC↓, 3,   Thiols↓, 3,   i-Thiols↓, 1,   Trx↓, 6,   Trx↑, 1,   Trx1↓, 1,   ox-Trx1↑, 1,   Trx2↓, 1,   TrxR↓, 30,   TrxR↑, 1,   TrxR1↓, 10,   TrxR1↑, 1,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 6,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 5,   Ferritin↑, 1,   FTH1↓, 3,   IronCh↑, 4,   IRP1↑, 1,   Mets↑, 1,   NCOA4↑, 2,   Tf↓, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   CDC2↓, 3,   CDC25↓, 9,   CDC25↑, 2,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   compIII↑, 1,   EGF↓, 1,   ETC↓, 10,   ETC↝, 1,   HSP60/HSPD1↑, 1,   Insulin↓, 4,   MCU↓, 1,   mitResp↓, 8,   mitResp↑, 2,   MKK7↓, 1,   mtDam↑, 45,   OCR↓, 13,   OCR↑, 3,   mt-OCR↓, 1,   OXPHOS↓, 9,   OXPHOS↑, 6,   OXPHOS⇅, 1,   OXPHOS↝, 3,   mt-OXPHOS↑, 2,   PDH↓, 4,   PDH↑, 1,   p‑PDH↓, 1,   PGC-1α↑, 4,   PINK1↑, 4,   SDH↓, 3,   SIRT3↓, 1,   SIRT3↑, 1,   TrxR2↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 3,   5LO↓, 4,   ACC↓, 2,   ACC↑, 1,   p‑ACC↑, 1,   ACLY↓, 7,   p‑ACLY↓, 1,   ACSL4↑, 2,   adiP↑, 2,   ADO↓, 1,   ALAT↓, 2,   ALAT∅, 1,   ALDOA↓, 2,   AMP↑, 1,   AMPK↑, 25,   AMPK↝, 1,   p‑AMPK↑, 3,   ATP↓, 43,   ATP↑, 1,   ATP∅, 1,   i-ATP↓, 1,   i-ATP↑, 1,   Buty↑, 2,   CAIX/CA9↓, 2,   citrate↓, 1,   CPT1A↓, 1,   CRM↑, 1,   CRM↝, 1,   ECAR↓, 6,   ECAR↝, 1,   ENO1↓, 3,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 3,   FASN↑, 2,   FBPase↑, 1,   GAPDH↓, 3,   GLS↓, 1,   glucoNG↑, 1,   glucose↓, 2,   glucose↑, 1,   glucose∅, 1,   GlucoseCon↓, 15,   GlucoseCon↑, 2,   GlucoseCon∅, 1,   glut↓, 1,   glyC↓, 1,   Glycolysis↓, 51,   Glycolysis↑, 3,   Glycolysis↝, 1,   GSK‐3β↓, 10,   GSK‐3β↑, 4,   p‑GSK‐3β↓, 4,   p‑GSK‐3β↑, 1,   Histones↑, 1,   HK1↓, 1,   HK2?, 1,   HK2↓, 24,   HK2↑, 1,   HK2∅, 1,   HMG-CoA↓, 3,   KeyT↑, 1,   lactateProd↓, 26,   lactateProd↑, 4,   lactateProd∅, 1,   e-lactateProd↓, 1,   LDHA↓, 12,   LDHA↑, 1,   LDHA∅, 1,   LDL↓, 4,   lipidLev↓, 1,   lipidLev↑, 1,   lipoGen↓, 1,   MCT4↓, 1,   NAD↓, 2,   NADPH↓, 8,   NADPH↑, 1,   NH3↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 9,   PDKs↓, 4,   PFK↓, 6,   PFK1↓, 2,   PFK2?, 1,   PFK2↓, 1,   PFKP↓, 2,   PGK1↓, 2,   PGM1↓, 1,   PGM1∅, 1,   PKM2↓, 20,   p‑PKM2↓, 1,   polyA↓, 1,   PPP↓, 2,   PPP↑, 1,   Pyruv↓, 1,   SCD1↓, 3,   SCFAs↑, 2,   SIRT1↓, 9,   SIRT1↑, 6,   SREBP1/SREBF1↓, 2,   SREBP2↓, 1,   TCA?, 1,   TCA↓, 2,   TCA↑, 2,   TCA↝, 1,   TS↓, 3,   UGDH↓, 2,   Warburg↓, 11,   Warburg↑, 1,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 18,   APAF1↑, 5,   Apoptosis?, 1,   Apoptosis↓, 12,   Apoptosis↑, 357,   mt-Apoptosis↑, 6,   ASC↓, 1,   ASK1↑, 2,   p‑ASK1↑, 1,   aSmase↑, 1,   BAD↓, 1,   BAD↑, 10,   Bak↓, 1,   Bak↑, 11,   BAX↓, 6,   BAX↑, 145,   Bax:Bcl2↑, 38,   Bcl-2↓, 155,   Bcl-2↑, 4,   Bcl-2∅, 1,   Bcl-xL↓, 38,   Bcl-xL↑, 3,   BID↓, 1,   BID↑, 7,   p‑BID↓, 1,   cl‑BID↑, 2,   BIM↑, 7,   BNIP3?, 2,   BNIP3↑, 1,   BNIP3↝, 1,   Casp↓, 1,   Casp↑, 55,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp12?, 1,   Casp12↑, 2,   pro‑Casp12↓, 1,   Casp2↑, 3,   Casp3↓, 4,   Casp3↑, 176,   cl‑Casp3↑, 51,   cl‑Casp3∅, 1,   proCasp3↓, 3,   proCasp3↑, 3,   CASP4↑, 1,   Casp6↑, 1,   Casp7↑, 20,   cl‑Casp7↑, 5,   Casp8↓, 2,   Casp8↑, 41,   Casp8∅, 2,   cl‑Casp8↑, 4,   proCasp8↑, 2,   Casp9↓, 1,   Casp9↑, 105,   cl‑Casp9↓, 1,   cl‑Casp9↑, 20,   proCasp9↓, 1,   proCasp9↑, 2,   cFLIP↓, 5,   Cupro↑, 3,   Cyt‑c↓, 1,   Cyt‑c↑, 121,   Cyt‑c↝, 1,   Diablo↑, 5,   DIDO1/DIO-1↑, 1,   DR5↑, 23,   Endon↑, 1,   FADD↑, 5,   Fap1↓, 1,   Fas↓, 2,   Fas↑, 15,   FasL↓, 1,   FasL↑, 13,   FasL⇅, 1,   Ferroptosis↓, 4,   Ferroptosis↑, 30,   GranB/GZMB↑, 1,   GranB/GZMB↝, 1,   GSDMD↑, 3,   GSDME↑, 1,   cl‑GSDME↑, 1,   GSDME-N↑, 2,   IAP1↓, 7,   IAP2/BIRC3↓, 3,   ICD↑, 5,   iNOS↓, 9,   iNOS↑, 1,   Mcl-1↓, 24,   p‑Mcl-1↓, 1,   cl‑Mcl-1↑, 1,   MDM2↓, 13,   MDM2↑, 1,   p‑MDM2↓, 1,   MLKL↑, 3,   p‑MLKL↓, 1,   MOMP↓, 2,   MOMP↑, 5,   Necroptosis↑, 7,   necrosis↑, 10,   NOXA↑, 6,   p38↓, 3,   p38↑, 25,   p‑p38↓, 1,   p‑p38↑, 12,   Paraptosis↑, 4,   Perforin↑, 1,   Perforin↝, 1,   PUMA↑, 7,   Pyro↑, 9,   RIP1↓, 2,   RIP1↑, 2,   RIP3↑, 3,   p‑RIP3↑, 2,   SK↓, 1,   survivin↓, 50,   TRAIL↑, 5,   TumCD↓, 4,   TumCD↑, 55,   TumCD∅, 2,   TUNEL↑, 1,   XIAP↓, 22,   YAP/TEAD↓, 7,   YAP/TEAD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 1,   Akt↓, 115,   Akt↑, 6,   p‑Akt↓, 37,   p‑Akt↑, 4,   AKT1↓, 2,   AMPKα↑, 4,   BRAF↓, 1,   CaMKII ↓, 2,   CaMKII ↑, 1,   CK2↓, 2,   cMET↓, 2,   CREB↑, 1,   cSrc↓, 1,   DDIT4↑, 1,   EGFR↓, 24,   EGFR↑, 2,   p‑EGFR↓, 1,   ERK↓, 32,   ERK↑, 12,   p‑ERK↓, 12,   p‑ERK↑, 8,   e-ERK↑, 1,   FOXD3↑, 1,   HCAR2↑, 1,   HER2/EBBR2↓, 8,   HGF/c-Met↓, 1,   Hippo↓, 2,   Hippo↝, 1,   IGF-1R↓, 2,   IGFR↓, 2,   IKKα↓, 7,   IKKα↑, 3,   p‑IKKα↓, 1,   IκB↑, 2,   p‑IκB↓, 2,   JAK↓, 2,   JAK1?, 1,   JAK1↓, 1,   p‑JAK1↓, 1,   JAK2↓, 8,   p‑JAK2↓, 5,   JNK↓, 6,   JNK↑, 33,   p‑JNK↑, 13,   LATS1↓, 1,   MAPK↓, 22,   MAPK↑, 16,   p‑MAPK↓, 1,   p‑MAPK↑, 6,   MEK↓, 2,   p‑MEK↓, 2,   p‑MEK↑, 1,   MKK4↓, 1,   MKP1↓, 1,   MKP2↓, 1,   Mst1↑, 1,   mTOR↓, 59,   mTOR↑, 3,   mTOR⇅, 1,   mTOR↝, 1,   p‑mTOR↓, 12,   mTORC2↓, 1,   mTORC2↑, 1,   p70S6↓, 2,   P70S6K↓, 2,   p‑P70S6K↓, 2,   p85S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 82,   PI3K↑, 5,   p‑PI3K↓, 4,   PI3K/Akt↓, 1,   PIK3CA↓, 1,   PIK3CA↑, 1,   PKA↓, 3,   PKA↑, 1,   PKCδ↓, 5,   PTEN↓, 1,   PTEN↑, 15,   p‑PTEN↓, 1,   Raf↓, 3,   RAS↓, 4,   p‑RSK↑, 1,   p‑S6K↓, 1,   Sp1/3/4↓, 7,   Src↓, 2,   p‑Src↓, 2,   STAT↓, 4,   STAT3↓, 54,   STAT3↑, 3,   STAT3⇅, 1,   STAT3↝, 1,   p‑STAT3↓, 15,   p‑STAT3↑, 2,   mt-STAT3↓, 1,   STAT6↓, 2,   p‑STAT6↓, 1,   p‑STK11/LKB1↑, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF3↑, 1,   ATF4↑, 10,   ATF4↝, 1,   CBP↓, 1,   ChrMod↑, 1,   cJun↓, 2,   cJun↑, 3,   p‑cJun↑, 1,   cMyc↓, 31,   cMyc↑, 1,   DNMT1↓, 4,   DNMT1↑, 1,   DNMT3A↓, 1,   DNMTs↓, 5,   EZH2↓, 1,   FOXO1↑, 2,   FOXO3↓, 2,   FOXO3↑, 5,   FOXO4↑, 2,   H3↓, 3,   p‑H3↓, 1,   p‑H3↑, 1,   ac‑H3↓, 1,   ac‑H3↑, 2,   H3K27ac∅, 1,   H4↓, 1,   ac‑H4↓, 1,   ac‑H4↑, 1,   HATs↓, 1,   HATs↑, 1,   HDAC↓, 26,   HDAC1↓, 4,   HDAC10↓, 1,   HDAC10↑, 1,   HDAC2↓, 1,   HDAC3↓, 2,   HDAC8↓, 2,   IRF1↑, 1,   KLF2↓, 1,   KLF5↓, 1,   miR-124-3p↓, 1,   miR-129-5p↑, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 1,   miR-155↓, 1,   miR-199↓, 1,   miR-200b↑, 1,   miR-200c↑, 1,   miR-203↑, 1,   miR-21↓, 1,   miR-218↑, 1,   miR-22↑, 1,   miR-29b↑, 1,   miR-30a-5p↑, 2,   miR-375↑, 1,   miR-490↑, 1,   Myc↓, 5,   n-MYC↓, 1,   NDRG1↑, 1,   OCT4↓, 10,   other?, 4,   other↓, 8,   other↑, 18,   other↝, 63,   other∅, 2,   PhotoS↑, 3,   SD↑, 1,   SETBP1↓, 1,   sonoS↑, 2,   SOX2↓, 7,   SOX4↑, 1,   SOX9↓, 1,   SUV39H↓, 3,   TCF-4↓, 1,   TFE3↑, 2,   tumCV?, 1,   tumCV↓, 113,   tumCV↑, 3,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 33,   e-CRT↑, 1,   EDEM↑, 1,   eIF2α↓, 1,   eIF2α↑, 6,   p‑eIF2α↓, 1,   p‑eIF2α↑, 8,   ER Stress↓, 2,   ER Stress↑, 80,   ER Stress↝, 1,   ERStress↑, 1,   GRP78/BiP?, 1,   GRP78/BiP↓, 5,   GRP78/BiP↑, 18,   HSF1↓, 1,   HSP27↓, 1,   HSP27↑, 1,   HSP70/HSPA5↓, 6,   HSP70/HSPA5↑, 4,   e-HSP70/HSPA5↑, 1,   HSP90↓, 13,   HSP90↑, 2,   e-HSP90↑, 2,   ac‑HSP90↑, 1,   HSPs↑, 2,   HSPs∅, 1,   IRE1↑, 4,   NPL4↓, 2,   PERK↑, 9,   p‑PERK↓, 1,   p‑PERK↑, 1,   Proteasome↓, 4,   PSMB5↓, 1,   UPR↓, 1,   UPR↑, 14,   mt-UPR↑, 1,   XBP-1↑, 6,   XBP-1↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

APA↑, 1,   ATG3↓, 1,   ATG5↑, 5,   ATG7↑, 1,   Beclin-1/ATG6↓, 2,   Beclin-1/ATG6↑, 14,   p‑Beclin-1/ATG6↑, 1,   LAMP1?, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 3,   LC3B↑, 3,   LC3B-II↑, 5,   LC3II↑, 19,   LC3s↑, 2,   lysoMP↓, 1,   lysoMP↑, 1,   MitoP↑, 3,   p62↓, 11,   p62↑, 6,   p‑p62↑, 1,   PARK2↑, 4,   SESN2↑, 3,   TFEB↑, 1,   TumAuto↓, 5,   TumAuto↑, 75,   TumAuto↝, 1,   mt-TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↓, 1,   ATM↑, 5,   ATR↑, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   BRCA2↓, 3,   DNA-PK↑, 2,   DNAdam↓, 5,   DNAdam↑, 97,   mt-DNAdam↑, 1,   DNArepair↓, 3,   hTERT/TERT↓, 7,   MDMX↓, 1,   NKX3.1↓, 2,   p16↑, 3,   P53↓, 6,   P53↑, 72,   P53↝, 3,   P53∅, 1,   p‑P53↑, 6,   p53 Wildtype↓, 1,   PARP↓, 6,   PARP↑, 16,   p‑PARP↑, 1,   cl‑PARP↑, 103,   cl‑PARP∅, 1,   proPARP↓, 1,   cl‑PARP1↑, 4,   PCNA↓, 12,   SIRT6↓, 2,   SIRT6↑, 1,   Telomerase↓, 16,   TOP1↓, 4,   TOP1↑, 1,   TOP1↝, 1,   TOP2↓, 2,   TOP2↑, 2,   TP53↓, 2,   TRF2↓, 1,   UHRF1↓, 1,   γH2AX↑, 12,   p‑γH2AX↑, 5,  

Cell Cycle & Senescence(tgid=11) ⓘ

ANAPC2↑, 1,   AURKB↑, 1,   CDK1?, 1,   CDK1↓, 11,   p‑CDK1↓, 1,   p‑CDK1↑, 1,   CDK2↓, 20,   CDK4↓, 31,   CDK4↑, 3,   p‑CDK4↓, 1,   CDK6↓, 11,   CDK6↑, 5,   CDK8↓, 1,   CDKN2C/p18↑, 1,   cellSen↑, 1,   CHK1↓, 1,   Chk2↑, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 8,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 22,   CycB/CCNB1↑, 5,   cycD1/CCND1↓, 56,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   CycD3↓, 2,   CycD3↑, 1,   cycE/CCNE↓, 13,   cycE/CCNE↑, 1,   cycF↑, 1,   E2Fs↓, 1,   GADD45A↑, 2,   Ki-67↓, 26,   mitA↓, 1,   mitA↑, 1,   p19↑, 1,   P21↓, 3,   P21↑, 57,   p27/CDKN1B↑, 22,   PLK1↓, 1,   RB1↑, 2,   p‑RB1↓, 4,   TubPol↓, 1,   TumCCA?, 1,   TumCCA↓, 6,   TumCCA↑, 228,   UBE2C↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 9,   ALDH1A1↓, 4,   BMI1↓, 3,   CD133↓, 9,   CD24↓, 3,   CD34↓, 1,   cFos↓, 2,   cFos↑, 1,   cMYB↓, 1,   CSCs↓, 48,   CSCs↑, 2,   CSCsMark↓, 1,   Diff↓, 1,   Diff↑, 4,   FGF↓, 2,   Gli↓, 1,   Gli1↓, 6,   HH↓, 8,   HMGCR↓, 1,   IGF-1?, 1,   IGF-1↓, 18,   IGF-1↑, 1,   IGF-1↝, 1,   IGF-1∅, 1,   IGF-2↓, 1,   IGFBP1↓, 1,   IGFBP1↑, 3,   IGFBP3↑, 3,   Ki-67↓, 26,   Let-7↑, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 10,   Nestin↓, 1,   NOTCH↓, 4,   NOTCH↑, 1,   NOTCH1↓, 5,   NOTCH1↑, 1,   NOTCH3↓, 1,   p300↓, 1,   Piezo1↑, 1,   PTCH1↓, 2,   Shh↓, 4,   Smo↓, 4,   STAT1↓, 1,   TumCG?, 1,   TumCG↓, 161,   TumCG↑, 5,   TumCG↝, 2,   TumCG∅, 1,   TumCP↓, 211,   TumCP↑, 7,   TumCP∅, 3,   Wnt?, 1,   Wnt↓, 27,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

Alix/AIP‑1↓, 1,   AntiAg↑, 2,   AP-1↓, 7,   ATPase↓, 1,   ATPase↑, 1,   AXL↓, 3,   BACH1↑, 1,   CA↓, 1,   Ca+2↓, 8,   Ca+2↑, 45,   Ca+2↝, 5,   i-Ca+2?, 1,   i-Ca+2↓, 1,   i-Ca+2↑, 3,   CAFs/TAFs↓, 2,   Cdc42↓, 2,   Cdc42↑, 1,   Chl↑, 1,   Chl∅, 1,   CTNNB1↓, 1,   E-cadherin↓, 3,   E-cadherin↑, 25,   EMT↓, 44,   EMT↑, 1,   EpCAM↓, 1,   F-actin↓, 1,   FAK↓, 10,   p‑FAK↓, 2,   p‑FAK↑, 1,   FOSB↑, 1,   GLI2↓, 3,   hnRNPA1↓, 1,   ITGA1∅, 1,   ITGA5∅, 1,   ITGB1↓, 1,   ITGB1∅, 1,   ITGB3↓, 1,   ITGB3∅, 1,   ITGB4∅, 1,   KRAS↓, 2,   LEF1↓, 2,   LRP1↓, 1,   MALAT1↓, 1,   MET↓, 2,   p‑MET↓, 1,   MMP1↓, 6,   MMP13↓, 1,   MMP2↓, 52,   MMP2↑, 1,   MMP2∅, 1,   proMMP2↓, 1,   MMP3↓, 3,   MMP7↓, 4,   MMP9↓, 60,   MMP9↑, 2,   MMP9∅, 1,   MMPs↓, 20,   MTA1↓, 1,   MUC1↑, 1,   N-cadherin↓, 9,   N-cadherin↑, 1,   NEDD9↓, 1,   p‑p44↓, 1,   PAK1↓, 3,   PAK1↑, 1,   PDGF↓, 3,   Rac1↓, 1,   Rho↓, 5,   ROCK1↓, 2,   Slug↓, 4,   Smad1↓, 1,   SMAD3↓, 2,   Snail?, 1,   Snail↓, 16,   SPARC↑, 1,   TET1?, 1,   TET1↑, 2,   TGF-β↓, 5,   TGF-β1↓, 2,   TIMP1↓, 1,   TIMP1↑, 2,   TIMP2↓, 1,   TIMP2↑, 6,   TRIB3↑, 1,   TSC1↑, 1,   TSP-1↑, 2,   TumCA↓, 2,   TumCI?, 1,   TumCI↓, 62,   TumCI↑, 1,   TumCMig↓, 66,   TumCMig↑, 2,   TumMeta↓, 62,   TumMeta↑, 5,   TumPF↓, 1,   Twist↓, 10,   TXNIP↑, 1,   Tyro3↓, 1,   uPA↓, 9,   uPAR↓, 2,   Vim↓, 16,   Vim↑, 1,   Zeb1↓, 8,   ZEB2↓, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 39,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 91,   angioG↑, 4,   angioG∅, 1,   CD31/PECAM-1↓, 1,   EGR1↑, 1,   Endoglin↑, 1,   eNOS↑, 1,   HIF-1↓, 1,   Hif1a↓, 48,   Hif1a↑, 3,   Hypoxia↓, 1,   LOX1↓, 1,   NO↓, 1,   NO↑, 8,   PHDs↓, 1,   VCAM-1↓, 2,   VEGF↓, 65,   VEGFR1↓, 3,   VEGFR2/KDR/Flk1↓, 5,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 2,   BBB↑, 8,   BBB∅, 1,   CellMemb↓, 1,   CellMemb↑, 6,   CLDN1↓, 2,   CLDN1↑, 1,   CLDN2↓, 1,   CLDN2↑, 1,   CTR1↑, 1,   EPR↓, 1,   EPR↑, 19,   EPR↝, 1,   GLUT1↓, 15,   GLUT1↑, 1,   GLUT2↓, 1,   GLUT3↓, 2,   GLUT4↓, 3,   IBI↑, 2,   KCNH2/hERG↓, 1,   LAT↓, 1,   MMP?, 1,   MMP↓, 198,   MMP↑, 1,   MPT↑, 11,   NHE1↓, 2,   OATPs↓, 1,   OCLN↑, 1,   SLC12A5↓, 2,   SMCT1∅, 1,   sonoP↑, 2,   TJ↓, 1,   TJ↑, 1,   TRPM7↓, 2,   TRPV1↑, 5,   VGCC↑, 1,   VGSC↑, 1,   ZO-1↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD14↓, 1,   CD4+↓, 1,   CD4+↑, 2,   CD44↓, 12,   CD47↓, 1,   CD8+↑, 9,   cDC2↓, 4,   cGAS–STING↑, 1,   COX1↓, 2,   COX2/PTGS2↓, 48,   COX2/PTGS2↑, 5,   CR3↝, 1,   CXCR2↓, 1,   CXCR4↓, 11,   DCells↑, 1,   Dectin1↝, 1,   DR4↑, 6,   DR4∅, 1,   DR6↑, 1,   Eos↑, 1,   Gal1↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   e-HMGB1↑, 1,   ICAM-1↓, 3,   IFN-γ↓, 1,   IFN-γ↑, 5,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 3,   IL1↑, 2,   IL10↓, 3,   IL10↑, 2,   IL12↓, 1,   IL12↑, 1,   IL17↑, 1,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 12,   IL1β↑, 1,   IL2↓, 2,   IL2↑, 6,   IL4↓, 3,   IL6↓, 25,   IL6↑, 1,   IL7↓, 1,   IL8↓, 6,   IL8↑, 1,   Imm↑, 36,   Imm↝, 3,   Inflam↓, 33,   Inflam↑, 1,   IRAK4↓, 1,   pol-M1↑, 1,   pol-M1↝, 1,   M2 MC↓, 3,   pol-M2 MC↓, 1,   MCP1/CCL2↓, 3,   MIP2↓, 1,   Neut↓, 1,   NF-kB↓, 105,   NF-kB↑, 5,   p‑NF-kB↓, 1,   p‑NF-kB↑, 1,   NK cell↑, 15,   NLRP3↓, 2,   NLRP3↑, 3,   p50↓, 1,   p65↓, 7,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 12,   PD-L1↑, 4,   PDT+↓, 1,   PGE2↓, 13,   PSA↓, 13,   RANTES↓, 1,   SOCS1↑, 1,   T-Cell↑, 2,   T-Cell↝, 1,   TCF↓, 3,   TCF↝, 1,   TLR1↑, 1,   TLR2↓, 1,   TLR4↓, 5,   TNF-α↓, 19,   TNF-α↑, 2,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRAF1↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

ADAM17↓, 1,   GFAP↓, 1,   pH↑, 7,   pH↝, 2,   pH∅, 1,   e-pH↓, 1,   e-pH↑, 6,   i-pH↓, 1,   TAMS↑, 1,   Temp↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

6IL↑, 1,   ACTH↓, 1,   AR↓, 19,   AR↑, 1,   AR↝, 1,   AR-FL↓, 1,   AR-V7↑, 1,   CYP11A1↓, 1,   CYP19↓, 1,   CYP24A1↓, 1,   ER-α36↓, 1,   ER(estro)↓, 2,   Estro↝, 1,   FKBP5↓, 1,   GR↓, 1,   Leptin↓, 1,   PPARα↓, 1,   PPARγ↓, 1,   PPARγ↑, 3,   RANKL↓, 1,   SRC3↓, 1,   SXR↑, 1,   VDR↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCC2↓, 1,   BioAv↓, 49,   BioAv↑, 64,   BioAv↝, 12,   BioEnh?, 1,   BioEnh↑, 10,   CBR1↓, 1,   chemoR↓, 2,   ChemoSen?, 1,   ChemoSen↓, 6,   ChemoSen↑, 209,   ChemoSen↝, 1,   CompStab↓, 3,   CompStab↑, 4,   CompStab↝, 1,   CYP1A1↓, 2,   CYP1A1↑, 1,   DDS↑, 10,   Dose?, 16,   Dose↓, 8,   Dose↑, 22,   Dose⇅, 1,   Dose↝, 153,   Dose∅, 29,   DrugR↓, 1,   eff?, 5,   eff↓, 440,   eff↑, 816,   eff⇅, 4,   eff↝, 143,   eff∅, 26,   GSTA1↓, 2,   GSTZ1↓, 1,   GSTZ1↝, 1,   GSTZ1∅, 1,   Half-Life↓, 16,   Half-Life↑, 9,   Half-Life↝, 13,   Half-Life∅, 1,   MDR1↓, 6,   MRP↓, 2,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 21,   P-gp/ABCB1∅, 1,   P450↓, 2,   RadioS↓, 1,   RadioS↑, 81,   RadioS↝, 1,   RadioS∅, 1,   selectivity?, 2,   selectivity↓, 3,   selectivity↑, 199,   selectivity↝, 1,   selectivity∅, 2,   Synergy↑, 132,   Synergy∅, 1,   TET2↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AFP?, 1,   AFP↓, 3,   ALAT↓, 2,   ALAT∅, 1,   ALB∅, 1,   ALP↓, 2,   AR↓, 19,   AR↑, 1,   AR↝, 1,   ascitic↓, 1,   AST↓, 2,   AST∅, 1,   BG↓, 6,   BMD↑, 2,   BP↓, 1,   BRAF↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CA125↓, 1,   CA125∅, 1,   CA19-9↓, 1,   CEA↓, 3,   CRP↓, 2,   CRP∅, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 24,   EGFR↑, 2,   p‑EGFR↓, 1,   EZH2↓, 1,   Ferritin↓, 5,   Ferritin↑, 1,   Hcy/homoC↓, 4,   Hcy/homoC↝, 1,   HER2/EBBR2↓, 8,   HOMA↓, 1,   hTERT/TERT↓, 7,   IL6↓, 25,   IL6↑, 1,   KeyT↑, 1,   KRAS↓, 2,   LDH?, 1,   LDH↓, 8,   LDH↑, 4,   LDH↝, 1,   i-LDH↓, 1,   Myc↓, 5,   NOS2↑, 1,   NSE↓, 1,   PD-L1↓, 12,   PD-L1↑, 4,   PSA↓, 13,   TP53↓, 2,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiCan↓, 3,   AntiCan↑, 80,   AntiCan∅, 1,   AntiDiabetic↑, 1,   antiNeop↑, 4,   AntiTum↓, 3,   AntiTum↑, 34,   AntiTum⇅, 1,   cachexia↓, 2,   cardioP↑, 10,   CardioT↓, 1,   CardioT↑, 2,   CardioT↝, 1,   chemoP↑, 40,   chemoP↝, 1,   chemoPv↑, 19,   ChemoSideEff↓, 15,   cognitive↑, 5,   fatigue↓, 3,   hepatoP↓, 1,   hepatoP↑, 8,   memory↑, 2,   motorD↑, 1,   Mucositis↓, 1,   MusCon↓, 2,   neuroP↑, 7,   NKG2D↑, 1,   NP/CIPN↓, 1,   NP/CIPN↑, 2,   OS?, 2,   OS↑, 65,   OS↝, 1,   OS∅, 1,   PARP16↓, 1,   PFS?, 1,   PFS↑, 3,   QoL↑, 12,   QoL∅, 3,   radioP↑, 20,   radioP↝, 1,   Remission↑, 4,   RenoP↑, 4,   Risk↓, 35,   Risk↑, 1,   Risk∅, 4,   Sleep↑, 1,   Strength∅, 1,   toxicity↓, 51,   toxicity↑, 8,   toxicity⇅, 1,   toxicity↝, 25,   toxicity∅, 7,   TumVol↓, 58,   TumW↓, 29,   Weight↓, 1,   Weight↑, 7,   Weight∅, 5,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiP↑, 2,   Bacteria↓, 4,   Dectin1↝, 1,   GutMicro↑, 13,   GutMicro↝, 3,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 4,  
Total Targets: 1244

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 10,   antiOx↑, 99,   mt-antiOx↑, 1,   ARE↑, 2,   Bil↓, 1,   Catalase↓, 1,   Catalase↑, 37,   Copper↓, 1,   CoQ10↑, 1,   DPPH↓, 1,   Fenton↓, 3,   GPx↑, 26,   GPx1↑, 1,   GPx4↓, 1,   GPx4↑, 3,   GPx4∅, 1,   GSH↓, 3,   GSH↑, 48,   GSR↑, 4,   GSTs↑, 8,   H2O2↓, 5,   H2O2↑, 1,   HDL↓, 1,   HDL↑, 5,   HDL∅, 2,   HO-1?, 1,   HO-1↓, 1,   HO-1↑, 28,   HO-1↝, 1,   HO-1∅, 1,   hyperG↓, 1,   Iron↓, 3,   Keap1↓, 2,   Keap1↑, 1,   lipid-P↓, 33,   lipid-P↑, 1,   mt-lipid-P↓, 1,   MDA↓, 30,   MDA↑, 1,   MDA∅, 1,   MPO↓, 5,   MPO↑, 1,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 7,   Nrf1↑, 1,   NRF2↓, 4,   NRF2↑, 51,   NRF2⇅, 1,   NRF2∅, 1,   Prx↑, 1,   RNS↓, 5,   ROS?, 4,   ROS↓, 133,   ROS↑, 14,   ROS⇅, 3,   ROS↝, 1,   ROS∅, 7,   mt-ROS↓, 1,   mt-ROS↑, 2,   selenoP↑, 4,   SOD↓, 3,   SOD↑, 59,   SOD1↑, 2,   TAC↑, 7,   TBARS↓, 4,   Trx↑, 2,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 4,   VitE↓, 1,   VitE↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FPN↑, 1,   IronCh↑, 6,   IronCh↝, 1,   Mets↝, 1,   NCOA4↝, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   compII↑, 1,   compIII↓, 1,   compIII↑, 1,   DRP1/DNM1L↑, 1,   ETC↓, 1,   ETC↑, 1,   FIS1↓, 1,   FIS1↑, 1,   Insulin↓, 3,   Insulin↑, 1,   mitResp↑, 2,   mtDam↓, 6,   OCR↑, 1,   mt-OCR↑, 1,   OXPHOS↑, 1,   PGC-1α↑, 4,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12-HETE↓, 1,   12LOX↓, 3,   5-HETE↓, 1,   5LO↓, 3,   ACSL4∅, 1,   adiP↓, 1,   adiP↑, 2,   ALAT↓, 15,   ALAT∅, 1,   AMPK↓, 1,   AMPK↑, 6,   ATP↓, 3,   ATP↑, 9,   BHB↑, 1,   cAMP↑, 2,   DHA↑, 1,   ECAR↓, 1,   ECAR↑, 1,   Eic↓, 1,   mt-FAO↑, 1,   glucose↓, 4,   glucose↑, 1,   GlucoseCon↑, 4,   Glycolysis↓, 1,   GSK‐3β↓, 4,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   p‑GSK‐3β↑, 1,   KeyT↑, 4,   lactateProd↓, 1,   LDL↓, 14,   lipidLev↓, 1,   NAD↑, 1,   NADH:NAD↑, 1,   NADPH↓, 2,   NADPH↑, 3,   PKM2↓, 2,   SCD1↓, 1,   SIRT1↓, 1,   SIRT1↑, 8,   SIRT2↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 15,   Apoptosis∅, 2,   ASK1↓, 1,   BAX↓, 6,   BAX↑, 2,   Bax:Bcl2↓, 2,   Bcl-2↓, 2,   Bcl-2↑, 3,   Bcl-2∅, 1,   Bcl-xL↓, 1,   Bcl-xL↑, 1,   Casp12↓, 2,   Casp3↓, 16,   Casp3↑, 2,   Casp3∅, 1,   cl‑Casp3↓, 2,   cl‑Casp8↑, 1,   Casp9↓, 6,   Casp9↑, 1,   Cyt‑c↓, 5,   Cyt‑c↑, 3,   Cyt‑c∅, 3,   Ferroptosis↓, 4,   GranB/GZMB↓, 1,   HEY1↑, 1,   iNOS↓, 13,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 1,   p38↑, 2,   p‑p38↓, 1,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 7,   e-Akt↑, 1,   AKT1↓, 1,   Akt2↓, 1,   AMPKα↑, 1,   CREB↑, 1,   ERK↓, 1,   ERK↑, 4,   e-ERK↑, 1,   HCAR2↑, 1,   IKKα↓, 1,   IκB?, 1,   JAK2↑, 1,   JNK↓, 4,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 7,   MAPK↑, 6,   Mst1↓, 1,   mTOR↓, 5,   mTOR↑, 1,   mTOR↝, 1,   p‑mTOR↓, 1,   p‑mTOR↑, 1,   PI3K↓, 4,   PI3K↑, 4,   PKA↑, 2,   PKCδ?, 1,   PKCδ↓, 1,   PKCδ↑, 1,   PP2A↑, 1,   PTEN↓, 2,   RAS↓, 1,   STAT↓, 1,   STAT3↓, 3,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 4,   ATF4↓, 1,   FOXO↑, 1,   HDAC↓, 1,   other?, 4,   other↓, 9,   other↑, 27,   other↝, 44,   SOX9↑, 1,   tumCV↓, 1,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   cl‑eIF2α↑, 1,   ER Stress↓, 6,   ER Stress↑, 1,   GRP78/BiP↓, 4,   GRP78/BiP↑, 1,   HSF1↑, 2,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 2,   HSP70/HSPA5↝, 1,   HSPs↑, 3,   IRE1↓, 2,   p‑PERK↑, 1,   UPR↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

CTSZ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   MitoP↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 13,   DNAdam↑, 2,   DNArepair↑, 3,   P53↑, 2,   PARP↓, 1,   γH2AX↓, 1,   p‑γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   E2Fs↑, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   Choline↑, 1,   Diff↑, 4,   Diff↝, 1,   FGF↑, 1,   IGF-1↓, 2,   IGFBP3↑, 1,   neuroG↑, 1,   NOTCH↑, 1,   TumCP↓, 2,   tyrosinase↓, 1,   Wnt↑, 2,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 12,   ARG1/2↑, 1,   Ca+2↓, 3,   Ca+2↑, 7,   Ca+2↝, 4,   cal2↓, 1,   Cartilage↑, 1,   COL1↓, 1,   COL2A1↑, 1,   E-cadherin↑, 1,   EMT↓, 2,   EMT↑, 1,   F-actin↑, 1,   FAK↑, 2,   MLC2/MYL9↝, 1,   MMP13↓, 1,   MMP2↓, 2,   MMP2↑, 2,   MMP9↓, 11,   MMP9↑, 2,   MMPs↓, 1,   MMPs↑, 1,   PAI-1/SERPINE1↓, 1,   SMAD3↓, 2,   Snail↑, 1,   TG2/TGase↓, 1,   TGF-β↓, 1,   TGF-β↑, 4,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   Twist↑, 1,   Vim↓, 1,   Vim↑, 1,   α-SMA↓, 1,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 2,   CD31/PECAM-1↑, 1,   eNOS↑, 1,   Hif1a↓, 2,   Hif1a↑, 2,   Hif1a∅, 1,   NO?, 1,   NO↓, 13,   NO↑, 4,   VCAM-1↓, 2,   VEGF↓, 2,   VEGF↑, 5,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 38,   BBB↝, 1,   BBB∅, 2,   CellMemb↑, 1,   CLDN1↓, 1,   CLDN1↑, 1,   CLDN1↝, 1,   EPR↑, 1,   GastroP↑, 5,   GLUT1↑, 2,   GLUT3↑, 1,   GLUT4↑, 1,   IBI↑, 1,   ketosis↑, 1,   MMP↓, 4,   MMP↑, 10,   MMP↝, 1,   MMP∅, 2,   MPT↑, 1,   OCLN↝, 1,   TJ↓, 1,   TJ↑, 2,   TRPV3↑, 1,   VGCC↑, 2,   VGCC⇅, 1,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 1,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD14↑, 1,   CD25+↑, 1,   CD4+↑, 3,   CD8+↑, 2,   COX1↓, 4,   COX2/PTGS2↓, 22,   CXCR4↓, 1,   Eos↓, 1,   FOXP3↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   IFN-γ↓, 3,   IFN-γ↑, 2,   IgE↓, 1,   IL1↓, 2,   IL10?, 1,   IL10↓, 2,   IL10↑, 9,   IL10∅, 1,   IL17↓, 7,   IL17∅, 1,   IL18↓, 1,   IL1α↓, 1,   IL1β↓, 26,   IL2↓, 2,   IL22↓, 1,   IL23↓, 1,   IL4↓, 1,   IL4↑, 3,   IL4∅, 1,   IL5↑, 1,   IL6↓, 33,   IL6↑, 4,   IL8↓, 3,   Imm↑, 18,   Imm⇅, 1,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 130,   Inflam↑, 2,   IRF3↓, 1,   LPS↓, 2,   M2 MC↑, 1,   MCP1/CCL2↓, 4,   MCP1/CCL2↑, 1,   MIP‑1α/CCL3↓, 1,   MyD88↓, 2,   NeuroI↓, 1,   NF-kB↓, 31,   NF-kB↑, 2,   NK cell↑, 1,   NLRP3↓, 5,   NLRP3↑, 1,   p65↓, 1,   PAF↓, 1,   PGE2↓, 9,   PSA↓, 1,   TLR1↓, 1,   TLR2↓, 2,   TLR4↓, 4,   TNF-α↓, 48,   TNF-α↑, 1,   Treg lymp↑, 1,   Treg lymp↝, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,   Temp↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 1,   5HT↓, 1,   5HT↑, 2,   Ach?, 1,   Ach↑, 6,   AChE↓, 24,   AChE∅, 2,   ADAM10↑, 1,   BChE↓, 9,   BDNF↑, 15,   BrainVol↑, 1,   BrainVol∅, 1,   ChAT↑, 1,   GABA↑, 3,   MAOA↓, 2,   NMDAR↑, 1,   PSD95↑, 1,   SNAP25↑, 1,   TrkB↑, 1,   β-Endo↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   APP↓, 4,   Aβ↓, 32,   Aβ42↓, 1,   BACE/β-secretase↓, 8,   IDE↑, 1,   tau↓, 4,   p‑tau↓, 8,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

BNP↓, 1,   GPER↑, 1,   GR↑, 2,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv?, 1,   BioAv↓, 36,   BioAv↑, 66,   BioAv⇅, 1,   BioAv↝, 24,   BioAv∅, 1,   BioEnh↑, 8,   ChemoSen↑, 1,   CompStab↓, 1,   CompStab↑, 5,   CompStab↝, 2,   CYP1A1↓, 1,   CYP2C19↓, 1,   CYP2C8↓, 1,   CYP2C9↓, 1,   CYP2D6↓, 1,   CYP2E1↓, 1,   CYP3A4↓, 2,   DDS↑, 1,   Dose?, 2,   Dose↓, 8,   Dose↑, 7,   Dose⇅, 1,   Dose↝, 93,   Dose∅, 2,   eff?, 2,   eff↓, 37,   eff↑, 264,   eff↝, 36,   eff∅, 2,   GSTA1↓, 2,   GSTA1↑, 1,   Half-Life↓, 5,   Half-Life↑, 7,   Half-Life⇅, 1,   Half-Life↝, 14,   Half-Life∅, 4,   P-gp/ABCB1↓, 3,   P450↓, 1,   selectivity↑, 2,   Synergy↑, 13,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 15,   ALAT∅, 1,   ALP↓, 4,   ALP↑, 1,   anemia↓, 1,   AST↓, 15,   AST∅, 1,   BG↓, 1,   Bil↓, 1,   BloodF↑, 3,   BMD↑, 7,   BP↓, 16,   BP∅, 1,   BUN↓, 3,   creat↓, 6,   CRP↓, 7,   Ferritin↓, 1,   FEV1↑, 2,   Hcy/homoC↓, 2,   HemoG↑, 1,   hs-CRP↓, 1,   IL6↓, 33,   IL6↑, 4,   KeyT↑, 4,   LDH↓, 6,   LDH↑, 1,   LDH∅, 1,   NLR↓, 1,   NOS2↓, 2,   PEF↑, 1,   PSA↓, 1,   PV↓, 1,   RBC↑, 1,   SpO2↑, 1,   TC↓, 1,   TMAO↑, 3,   TMAO⇅, 1,   UFR?, 1,   UFR↑, 1,   UR↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 5,   antiAll↑, 15,   antiAll∅, 1,   AntiArt↑, 7,   AntiCan↑, 11,   antiD↓, 1,   AntiDiabetic↑, 18,   antiPs↑, 1,   AntiTum↓, 1,   AntiTum↑, 3,   BOLD↑, 2,   Bone Healing↑, 1,   cachexia↓, 1,   cardioP↑, 37,   CardioT↓, 3,   chemoP↑, 10,   chemoPv↑, 5,   cognitive?, 1,   cognitive↓, 3,   cognitive↑, 71,   cognitive∅, 1,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 1,   hepatoP↑, 31,   IPSS↝, 1,   Learn↑, 1,   memory↓, 2,   memory↑, 41,   memory∅, 1,   Mood?, 1,   Mood↑, 5,   motorD↓, 1,   motorD↑, 13,   MusCon↓, 1,   Nausea↓, 1,   neuroP?, 1,   neuroP↑, 73,   Obesity↓, 8,   OS↓, 1,   OS↑, 5,   Pain↓, 9,   PDE4↓, 1,   QoL↑, 1,   radioP↑, 4,   RenoP↑, 15,   Risk↓, 8,   Risk↑, 2,   Sleep↑, 5,   Strength↑, 2,   Stress↓, 3,   Stroke↓, 8,   toxicity?, 3,   toxicity↓, 78,   toxicity↑, 7,   toxicity↝, 11,   toxicity∅, 27,   Vomit↓, 1,   Weight↓, 4,   Weight↑, 1,   Weight↝, 1,   Weight∅, 1,   Wound Healing↓, 1,   Wound Healing↑, 11,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 7,   AntiFungal↑, 4,   AntiP↓, 1,   AntiP↑, 2,   AntiViral↑, 13,   Bacteria↓, 26,   Diar↓, 1,   Dysb↓, 1,   GutMicro↑, 15,   GutMicro↝, 1,   Inf↓, 1,   Sepsis↓, 7,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 2,   Ingr↝, 5,   Phen↑, 1,  
Total Targets: 612

Scientific Paper Hit Count for: eff, efficacy
64 Silver-NanoParticles
59 Magnetic Fields
33 Sulforaphane (mainly Broccoli)
28 Thymoquinone
27 Curcumin
26 immunotherapy
26 Shikonin
25 Chemotherapy
25 Vitamin C (Ascorbic Acid)
23 chitosan
22 Selenite (Sodium)
21 Radiotherapy/Radiation
21 Baicalein
21 Selenium NanoParticles
20 Piperlongumine
19 Copper and Cu NanoParticles
19 EGCG (Epigallocatechin Gallate)
18 Artemisinin
17 Magnetic Field Rotating
16 Melatonin
16 Berberine
16 Exercise
15 Chlorogenic acid
14 Apigenin (mainly Parsley)
14 Luteolin
14 Phenylbutyrate
14 Caffeic acid
14 Capsaicin
14 Resveratrol
14 Quercetin
14 Gambogic Acid
13 Selenium
13 diet FMD Fasting Mimicking Diet
12 Gold NanoParticles
12 Citric Acid
12 Ashwagandha(Withaferin A)
12 Propolis -bee glue
12 Folic Acid, Vit B9
12 Dichloroacetate
12 Hydrogen Gas
11 3-bromopyruvate
11 Cisplatin
11 Betulinic acid
11 Ivermectin
11 Lycopene
11 Phenethyl isothiocyanate
10 Vitamin D3
10 Choline
10 diet Methionine-Restricted Diet
10 Disulfiram
10 Honokiol
9 Auranofin
9 Metformin
9 borneol
9 Electrical Pulses
9 Formononetin
9 Bicarbonate(Sodium)
8 Photodynamic Therapy
8 Fenbendazole
8 SonoDynamic Therapy UltraSound
8 chaetocin
8 doxorubicin
8 Fisetin
8 Hyperthermia
8 Plumbagin
8 Rosmarinic acid
7 Coenzyme Q10
7 Docetaxel
7 Boron
7 buckwheat sprouts
7 Ellagic acid
7 Chrysin
7 Dandelion Root
7 Juglone
7 VitK3,menadione
7 mebendazole
7 salinomycin
6 Alpha-Lipoic-Acid
6 beta-glucans
6 isoorientin
6 Carnosic acid
6 Celastrol
6 Vitamin B12
6 Chlorophyllin
6 Docosahexaenoic Acid
6 Eugenol
6 MCT oil
6 Flaxseed/Linseed
6 Ginger/6-Shogaol/Gingerol
6 isoquercitrin
6 MCT, metronomic chemo
6 Parthenolide
6 Vitamin K2
5 Astragalus
5 Akkermansia
5 Bevacizumab (brand Avastin)
5 Ascorbyl Palmitate
5 Lutein
5 Bifidobacterium
5 Boswellia (frankincense)
5 Piperine
5 Silymarin (Milk Thistle) silibinin
5 Cynaropicrin
5 Diclofenac
5 eicosapentaenoic acid
5 diet Plant based
5 Lemongrass Extract/Citral
5 Ginkgo biloba-EGb 761
5 Gossypol/AT-101
5 Isoliquiritigenin
5 Licochalcone A
5 Moringa oleifera
5 Nimbolide
5 Spermidine
5 Urolithin
4 chemodynamic therapy
4 EMF
4 Cynara scolymus/Globe Artichoke/Artichoke Extract
4 Allicin (mainly Garlic)
4 almonertinib
4 Berbamine
4 α-Bisabolol / Chamomile oil
4 Butyrate
4 capecitabine
4 Carvacrol
4 Cat’s Claw
4 Centella asiatica / Gotu kola → asiaticoside
4 CUSP9
4 diet Short Term Fasting
4 Echinacea
4 Kaempferol
4 phytic acid, Inositol hexakisphosphate
4 Fucoidan
4 Ginkgolide B
4 Ginseng
4 HydroxyCitric Acid
4 Magnolol
4 Isobavachalcone
4 Matrine
4 methylseleninic acid
4 Methylsulfonylmethane
4 Propyl gallate
4 Pterostilbene
4 Terpinen-4-ol / Tea Tree Oil
4 Whole Body Vibration
3 cetuximab
3 5-fluorouracil
3 Anthocyanins
3 Aspirin
3 Atorvastatin
3 Aloe anthraquinones
3 bempedoic acid
3 beta-carotene(VitA)
3 Zeaxanthin
3 Bortezomib
3 Bullatacin
3 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
3 Thymol-Thymus vulgaris
3 Cannabidiol
3 Chocolate
3 Cichoric acid / Chicoric acid
3 Crocetin
3 Cysteamine
3 erastin
3 Gallic acid
3 Gamma-aminobutyric acid
3 Ginkgo biloba
3 Lemon Balm/Melissa officinalis
3 Germanium Organic/Ge-132 / propagermanium (organogermanium)
3 Gemcitabine (Gemzar)
3 Hibiscus sabdariffa
3 HydroxyTyrosol
3 iodine
3 Inulin Prebiotic
3 isoflavones
3 Licorice
3 Lactoferrin/Talactoferrin
3 nicotinamide adenine dinucleotide
3 Radio Frequency
3 Sulfasalazine
3 Taurine
3 Vitamin B1/Thiamine
2 1,8-Cineole
2 2-DeoxyGlucose
2 Glucose
2 Zinc
2 Andrographis
2 Anti-oxidants
2 Vitamin A, Retinoic Acid
2 Aromatherapy
2 Astaxanthin
2 Arsenic trioxide
2 Baicalin
2 Huperzine A/Huperzia serrata
2 Beta-Caryophyllene
2 Bufalin/Huachansu
2 temozolomide
2 probiotics
2 brusatol
2 Vitexin
2 Isovitexin
2 Rutin
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Caffeine
2 Calcium
2 Celecoxib
2 Hydroxycinnamic-acid
2 Calorie Restriction Mimetics
2 Cyclopamine
2 Dichloroacetophenone(2,2-)
2 Deguelin
2 Date Fruit Extract
2 diet Ketogenic
2 Oxygen, Hyperbaric
2 D-limonene
2 statins
2 Emodin
2 Vitamin E
2 ferumoxytol
2 Paclitaxel/Taxol
2 SDG/lignans
2 tamoxifen
2 Garcinol
2 Geldanamycin
2 γ-linolenic acid (Borage Oil)
2 Grapeseed extract
2 Orlistat
2 hydroxychloroquine
2 Helleborus niger extracts – Christmas Rose
2 Hyperoside
2 itraconazole
2 Potassium
2 lambertianic acid
2 Lapachol
2 Methylene blue
2 Methyl Jasmonate
2 Magnesium
2 Mistletoe/Viscum album Extracts
2 Naringin
2 Marjoram (Origanum majorana)
2 Rauwolfia serpentina/Indian Snakeroot
2 Aflavin-3,3′-digallate
2 tetrathiomolybdate
2 Ursolic acid
1 5-Aminolevulinic acid
1 Anzaroot, Astragalus fasciculifolius Bioss
1 wortmannin
1 Resiquimod
1 Aidi injection
1 Acetyl-l-carnitine
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Amodiaquine
1 DTS(dibenzyl trisulphide) from Anamu
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Sorafenib (brand name Nexavar)
1 Trastuzumab
1 Biochanin A
1 Brucea javanica
1 Bacopa monnieri
1 Bromelain
1 Bruteridin(bergamot juice)
1 urea
1 Cannabichromene
1 Beta‐Lapachone
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 irinotecan
1 Carvone
1 Polyphenols
1 Black phosphorus
1 Cucurbitacin
1 gefitinib, erlotinib
1 Dasatinib/Phyrago
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 Dipyridamole
1 Protocatechuic acid
1 PXD, phenoxodiol
1 Eurycomanone
1 flavonoids
1 Flickering Light Stimulation
1 Flaxseed Oil
1 Galloflavin
1 verapamil
1 Salvia officinalis
1 Germanium inorganic
1 Geraniol
1 Germanium-Spirogermanium
1 Ginkgetin
1 Glabrescione B
1 Graviola
1 High-Ozonide Oil
1 Indole-3-carbinol
1 entinostat
1 Recombinant Methioninase
1 Lactobacillus
1 Laetrile B17 Amygdalin
1 Lapatinib
1 low dose naltrexone
1 Lecithin
1 Linalool
1 Mung Bean Sprouts
1 Modified Citrus Pectin
1 carboplatin
1 Methylglyoxal
1 magnetic nanoparticles
1 Mushroom Lion’s Mane
1 Mushroom Reishi
1 Myricetin
1 No Product/Mechanism Only
1 Oleocanthal
1 Peppermint
1 sericin
1 Phosphatidylserine
1 Pumpkin Seed Oil / Cucurbita pepo
1 Tamsulosin
1 enzalutamide
1 Rhein
1 Oxaliplatin
1 α-Santalol/Sandalwood oil
1 Scoulerine
1 polyethylene glycol
1 Iron
1 Squalene
1 Glutathione
1 Sutherlandioside D
1 Triphala
1 triptolide
1 Tumor Treating Fields
1 Turmerones
1 Vitamin B3,Niacin
1 Vitamin B5,Pantothenic Acid
1 Vitamin B6,pyridoxine
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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