Radiotherapy/Radiation Cancer Research Results

Rad, Radiotherapy/Radiation: Click to Expand ⟱
Features:
Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes.

Radiosensitizer
Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer.
-Hypoxia (low oxygen levels) within tumors is a major cause of resistance to radiotherapy


Scientific Papers found: Click to Expand⟱
6226- CUR,  Rad,    Analysis of Curcumin as a Radiosensitizer in Cancer Therapy with Serum Survivin Examination: Randomised Control Trial
- Trial, Cerv, NA
survivin↓, RadioS↑, toxicity↓,
6212- CUR,  Rad,    Radiosensitization and Radioprotection by Curcumin in Glioblastoma and Other Cancers
- Review, Var, NA
RadioS↑, *radioP↑, EGFR↓, TGF-β↓, ROS↑, P53↑, PI3K↓, NF-kB↓, COX2/PTGS2↓, EMT↓, Hif1a↓, HSP90↓, mTOR↓, *Catalase↑, *SOD↑, *MDA↑, *Wound Healing↑, *hepatoP↑, *NF-kB↓, *ROS↓,
1485- CUR,  Chemo,  Rad,    Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs
- Review, Var, NA
ChemoSen↑, NF-kB↓, *STAT3↓, *COX2/PTGS2↓, *Akt↓, *NRF2↑, *HO-1↑, *GPx↑, *NADPH↑, *GSH↑, *ROS↓, *p300↓, radioP↑, chemoP↑, RadioS↑,
1870- DCA,  Rad,    Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate cancer cells in vitro to radiation
- in-vitro, Pca, PC3
TumCCA↑, Apoptosis↑, MMP↓, eff↑, RadioS↑,
5195- DCA,  Rad,    Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells
- in-vitro, BC, 4T1 - in-vitro, BC, EMT6
PDKs↑, ROS↑, p‑PDH↓, ECAR↓, lactateProd↓, selectivity↓, RadioS↑,
5193- dietMet,  Rad,    A Phase I Trial of a Methionine Restricted Diet with Concurrent Radiation Therapy
- Trial, Var, NA
toxicity↝, other↝,
8854- DIM,  Rad,    3,3′-Diindolylmethane: A Promising Sensitizer of γ-Irradiation
- in-vitro, BC, MCF7
TumCCA↑, ROS↑, PARP↓, Apoptosis↑, TumCP↓, RadioS↑, Dose↝,
6351- DRE,  Rad,    Differential effect of Taraxacum officinale L. (dandelion) root extract on hepatic and testicular tissues of rats exposed to ionizing radiation
- in-vivo, Nor, NA
*radioP↑, *ROS↓, *MDA↓, *GSH↑, *SOD↑, *IL1β↓, *TNF-α↓, *Casp3↓, *eff↑,
5010- DSF,  Cu,  Rad,    Disulfiram/Copper Combined with Irradiation Induces Immunogenic Cell Death in Melanoma
- in-vivo, Melanoma, B16-F10
Apoptosis↑, ICD↑, HMGB1↑, ATP↓, TumCG↓,
1620- EA,  Rad,    Radiosensitizing effect of ellagic acid on growth of Hepatocellular carcinoma cells: an in vitro study
- in-vitro, Liver, HepG2
ROS↑, P53↑, TumCCA↑, IL6↓, COX2/PTGS2↓, TNF-α↓, MMP↓, angioG↓, MMP9↓, BAX↑, Casp3↑, Apoptosis↑, RadioS↑, TBARS↑, GSH↓, Bax:Bcl2↑, p‑NF-kB↓, p‑STAT3↓,
3213- EGCG,  Rad,    Epigallocatechin-3-gallate Enhances Radiation Sensitivity in Colorectal Cancer Cells Through Nrf2 Activation and Autophagy
- in-vitro, CRC, HCT116
RadioS↑, TumCP↓, NRF2↑,
3234- EGCG,  Rad,    EGCG, a tea polyphenol, as a potential mitigator of hematopoietic radiation injury in mice
- in-vivo, Nor, NA
*DNMTs↓, *radioP↑, *HDAC↑,
6333- Eug,  Cisplatin,  Rad,    Eugenol Exerts Apoptotic Effect and Modulates the Sensitivity of HeLa Cells to Cisplatin and Radiation
- in-vitro, Cerv, HeLa
TumCP↓, LDH↝, ChemoSen↑, RadioS↑, Casp3↑, BAX↑, Cyt‑c↑, Casp9↑, Bcl-2↓, COX2/PTGS2↓, IL1β↓, ROS↑, NF-kB↓, COX2/PTGS2↓, TumCCA↓, Thiols↓, GSH↓,
7518- FA,  Rad,    Radiosensitizing effect of ferulic acid on human cervical carcinoma cells in vitro
- in-vitro, Cerv, HeLa - in-vitro, Cerv, ME-180
lipid-P↑, ROS↑, DNAdam↑, RadioS↑,
1914- Fer,  VitC,  TMZ,  Rad,    Pharmacologic Ascorbate and Ferumoxytol Combined with Temozolomide and Radiation Therapy for the Treatment of Newly Diagnosed Glioblastoma
- Trial, GBM, NA
Synergy↑,
6906- FIS,  Rad,    Combining fisetin and ionizing radiation suppresses the growth of mammalian colorectal cancers in xenograft tumor models
- in-vivo, CRC, CT26 - in-vivo, CRC, HCT116
antiOx↑, Inflam↓, angioG↓, TumCI↓, TumCP↓, TumCG↓, RadioS↑,
8587- FS,  Rad,    Phase II Trial of Flaxseed to Prevent Acute Complications After Chemoradiation for Lung Cancer
- Trial, Lung, NA
*Dose↝, *eff↝,
832- GAR,  Rad,    Garcinol, a Histone Acetyltransferase Inhibitor, Radiosensitizes Cancer Cells by Inhibiting Non-Homologous End Joining
- in-vitro, Lung, A549 - in-vitro, NA, HeLa
HATs↓, other↑,
7100- Geld,  Rad,    Preferential sensitization of tumor cells to radiation by heat shock protein 90 inhibitor geldanamycin
- in-vitro, Var, NA
HSP90↓, Akt↓, RadioS↑, selectivity↑,
7279- GGB,  Rad,    Radioprotective effect of Ginkgolide B on brain: the mediating role of DCC/MST1 signaling
- in-vivo, Nor, NA
*cognitive↑, *radioP↑, *ROS↓, *p‑Akt↑, *Bcl-2↑, *Mst1↓, *p‑p38↓, *JNK↓, *cl‑Casp3↓, *BAX↓,
7287- GGB,  Rad,    Ginsenoside Rg3 enhances the radiosensitivity of lung cancer A549 and H1299 cells via the PI3K/AKT signaling pathway
- in-vitro, Lung, NA
TumCP↓, Apoptosis↑, TumCMig↓, RadioS↑, TumCCA↑, PI3K↓, p‑Akt↓, PDK1 / PDPK1↓,
4420- GoldNP,  Rad,    Computational modeling and experimental synthesis of BSA-coated bimetallic theranostic MnO₂-Au@curcumin nanoplatform for synergistic radiochemotherapy of breast cancer
- in-vitro, BC, 4T1
RadioS↑,
7307- GoldNP,  Rad,    Uptake and excretion dynamics of gold nanoparticles in cancer cells and fibroblasts
- in-vitro, GBM, U87MG - in-vitro, Cerv, HeLa - in-vitro, Pca, PC3 - in-vitro, PC, Bxpc-3
eff↑,
7306- GoldNP,  Rad,    Gold nanoparticles enhance the radiation therapy of a murine squamous cell carcinoma
- in-vivo, SCC, NA
Synergy↑, RadioS↑,
7305- GoldNP,  Rad,    The use of gold nanoparticles to enhance radiotherapy in mice
- in-vivo, Var, NA
Dose↝, selectivity↑, toxicity↝, RadioS↑,
1901- GoldNP,  Rad,    The role of thioredoxin reductase in gold nanoparticle radiosensitization effects
- in-vitro, Lung, A549
MMP↓, ROS↑, RadioS↑, TrxR↓,
3526- GoldNP,  Rad,    Advances in nanoparticle-based radiotherapy for cancer treatment
- Review, Var, NA
RadioS↑, EPR↑, ROS↑, TumCCA↑,
941- Gos,  Rad,    The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis
- in-vivo, Var, NA
lactateProd↓, other↓, TGF-β↓,
7481- H2,  Rad,    Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy
- Trial, Var, NA
Dose↝, CRP↓, NLR↓, IL6↓, AntiTum∅, *toxicity↓, Inflam↓, radioP↑, *IBI↑, *ROS↓,
3152- H2,  VitC,  Rad,    Hydrogen and Vitamin C Combination Therapy: A Novel Method of Radioprotection
- in-vitro, Nor, HUVECs - in-vivo, NA, NA
AntiTum↑, OS↑, QoL↑, TumVol↓, radioP↑, Dose↑, Dose↝, Synergy↑,
2902- HNK,  Rad,    Honokiol Mitigates Ionizing Radiation-Induced Injury by Maintaining the Redox Balance of the TrxR/Trx System
- in-vitro, Nor, BEAS-2B
*TrxR1↑, *Trx↑, *radioP↑, *ROS↓,
5053- HPT,  Rad,  Chemo,    Association of elevated reactive oxygen species and hyperthermia induced radiosensitivity in cancer stem-like cells
- in-vitro, Var, NA
CSCs↓, TumCP↓, ROS↑, RadioS↑,
7623- HPT,  Rad,    Enhancing radiosensitisation of BRCA2-proficient and BRCA2-deficient cell lines with hyperthermia and PARP1-i
- Review, Var, NA
BRCA2↓, RadioS↑, eff↑,
7572- HPT,  Rad,    The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination
- in-vitro, Cerv, HeLa - in-vitro, Laryn, FaDu
RadioS↑, TumCD↑, BRCA2↓, Dose↝, BloodF↑, ROS↑, Imm↑,
7651- HPT,  Rad,    Hyperthermia inhibits homologous recombination repair and sensitizes cells to ionizing radiation in a time- and temperature-dependent manner
- in-vitro, Var, NA
RadioS↑, DNArepair↓, Dose↑,
7649- HPT,  Rad,    A pilot study of the effects of mild systemic heating on human head and neck tumour xenografts: Analysis of tumour perfusion, interstitial fluid pressure, hypoxia and efficacy of radiation therapy
- in-vivo, Laryn, FaDu
Dose↝, BloodF↑, Hypoxia↓, RadioS?,
7627- HPT,  Rad,    Local control rate after the combination of re-irradiation and hyperthermia for irresectable recurrent breast cancer: Results in 248 patients
- Trial, BC, NA
CR↑, OS↑, *toxicity↝, RadioS↑,
7626- HPT,  Rad,    Dynamics of chromosomal aberrations, induction of apoptosis, BRCA2 degradation and sensitization to radiation by hyperthermia
- in-vitro, Var, NA
BRCA2↓, selectivity↑, RadioS↑, eff↝,
7621- HPT,  Rad,    Clinical effectiveness of combined whole body hyperthermia and external beam radiation therapy (EBRT) versus EBRT alone in patients with painful bony metastases: A phase III clinical trial study
- Trial, Pca, NA - Trial, BC, NA
Pain↓, Dose↝, CR↑,
7598- HPT,  Rad,  Chemo,    The role of capacitive hyperthermia as an adjunct treatment in oncology: a systematic review of randomized phase III trials
- Review, Var, NA
OS↑, TR↑, LC↑, *toxicity?,
7577- HPT,  Rad,    Randomized trial of hyperthermia and radiation for superficial tumors
- Trial, Var, NA
RadioS↑, eff↑, Dose↝,
7599- HPT,  Rad,    Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome
- Review, Var, NA
NA↑, RadioS↑, DNArepair↓, Hypoxia↓, EPR↑, LC↑, OS↑, *toxicity↓, Dose↝, BloodF↑, pH↝, Imm↑, HSP70/HSPA5↑,
7575- HPT,  Rad,  Chemo,  immuno,    From Localized Mild Hyperthermia to Improved Tumor Oxygenation: Physiological Mechanisms Critically Involved in Oncologic Thermo-Radio-Immunotherapy
- Analysis, Var, NA
RadioS↑, ChemoSen↑, Imm↑, BloodF↑, Hypoxia↓, Dose↝, DNArepair↓, e-pH↓,
7573- HPT,  Rad,    Heat-induced BRCA2 degradation in human tumours provides rationale for hyperthermia-PARP-inhibitor combination therapies
- vitro+vivo, Var, NA
RadioS↑, BRCA2↓,
7549- HYP,  Rad,    Study on the mechanism of hyperoside in affecting the biological progression and radiosensitivity of esophageal carcinoma by modulating the STAT3/AKT/ERK pathway
- vitro+vivo, ESCC, TE1 - vitro+vivo, ESCC, KYSE150
TumCP↓, TumCI↓, TumCMig↓, EMT↓, Apoptosis↑, RadioS↑, p‑STAT3↓, p‑Akt↓, p‑ERK↓,
7759- ISL,  Rad,    Isoliquiritigenin, a Bioactive Blood Component Derived from Licorice, Activates Nrf2 Enzymes to Confer Protection Against Radiation-Induced Nerve Injury
- vitro+vivo, Nor, PC12
*radioP↑, *LDH↓, *ROS↓, *SOD1↑, *GSH↑, *TAC↑, *NRF2↓, *cognitive↑, *Learn↑, *memory↑,
8066- KAE,  Rad,    Radiosensitization of non-small cell lung cancer by kaempferol
- in-vivo, Lung, A549
TumCG↓, selectivity↑, TumCCA↑, RadioS↑,
8404- LDN,  Rad,    Chemotherapeutic effects of luteolin on radio-sensitivity enhancement and interleukin-6/signal transducer and activator of transcription 3 signaling repression of oral cancer stem cells
- in-vitro, Oral, NA
TumCP?, ALDH1A1↓, CD44↓, selectivity↑, RadioS↑,
8270- LE,  Rad,    Comparative Study of the Effect of Licorice Muco-adhesive Film on Radiotherapy Induced Oral Mucositis, A Randomized Controlled Clinical Trial
- Trial, HNSCC, NA
Dose?, Pain↓, Mucositis↓,
8286- LE,  Rad,    Preventive Effect of Glycyrrhiza Glabra Extract on Oral Mucositis in Patients Under Head and Neck Radiotherapy: A Randomized Clinical Trial
- Trial, HNSCC, NA
Mucositis↓, radioP↑, Dose↝, Dose↝,

Showing Research Papers: 51 to 100 of 160
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 160

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↓, 1,   cystine↓, 1,   GPx↑, 1,   GPx4↓, 1,   GSH↓, 8,   GSH/GSSG↓, 1,   H2O2↑, 2,   HO-1↓, 1,   lipid-P↑, 2,   NRF2↓, 2,   NRF2↑, 2,   ROS↓, 2,   ROS↑, 41,   SOD↓, 1,   SOD2↓, 1,   TBARS↑, 1,   Thiols↓, 1,   Trx↓, 1,   TrxR↓, 3,   xCT/SLC7A11↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↓, 1,   mtDam↑, 1,   OCR↑, 1,   p‑PDH↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   ALDOA↓, 1,   AMPK↑, 1,   ATP↓, 2,   ECAR↓, 3,   GAPDH↓, 1,   glucose↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 2,   HK1↓, 1,   HK2↓, 1,   lactateProd↓, 2,   NADPH↑, 1,   PDK1 / PDPK1↓, 1,   PDKs↑, 1,   PKM2↓, 1,   PPP↑, 1,   Pyruv↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Apoptosis↑, 23,   BAX↓, 1,   BAX↑, 4,   Bax:Bcl2↑, 1,   Bcl-2↓, 6,   Bcl-xL↓, 1,   Casp3↑, 8,   cl‑Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 4,   Cyt‑c↑, 2,   Ferroptosis↑, 1,   ICD↑, 1,   p38↑, 2,   p‑p38↑, 1,   survivin↓, 1,   TumCD↑, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   Akt↑, 1,   p‑Akt↓, 3,   EGFR↓, 1,   ERK↓, 2,   ERK↑, 1,   p‑ERK↓, 1,   JNK↓, 1,   JNK↑, 1,   MAPK↓, 1,   mTOR↓, 1,   PI3K↓, 2,   PI3K↑, 1,   RAS↑, 1,   STAT3↓, 1,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

p‑FOXO3↓, 1,   HATs↓, 1,   HDAC↓, 1,   OCT4↓, 1,   other?, 1,   other↓, 1,   other↑, 1,   other↝, 3,   Prot↓, 1,   SOX2↓, 1,   tumCV↓, 6,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,   HSP70/HSPA5↑, 1,   HSP90↓, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   TumAuto↑, 4,  

DNA Damage & Repair(tgid=10) ⓘ

8-oxo-dG↓, 1,   BRCA2↓, 4,   DNAdam↓, 2,   DNAdam↑, 10,   DNArepair↓, 5,   P53↑, 4,   P53↝, 1,   PARP↓, 1,   cl‑PARP↑, 2,   PCNA↓, 1,   γH2AX↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   Ki-67↓, 1,   mitA↑, 1,   P21↓, 1,   TumCCA↓, 1,   TumCCA↑, 17,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   ALDH1A1↓, 1,   CSCs↓, 3,   Diff↑, 1,   EIF4E↓, 1,   Ki-67↓, 1,   mTORC1↓, 1,   TumCG↓, 8,   TumCP?, 1,   TumCP↓, 15,  

Migration(tgid=13) ⓘ

Cav1↓, 1,   EMT↓, 2,   MMP2↓, 2,   MMP9↓, 2,   TGF-β↓, 2,   TumCI↓, 4,   TumCMig↓, 5,   TumMeta↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 7,   Hif1a↓, 5,   Hypoxia↓, 3,   VCAM-1↓, 1,   VEGF↓, 4,  

Barriers & Transport(tgid=15) ⓘ

EPR↑, 2,   MMP↓, 7,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD44↓, 1,   COX2/PTGS2↓, 4,   Gal-3↓, 1,   HMGB1↑, 1,   IL1β↓, 2,   IL6↓, 2,   Imm↑, 4,   Inflam↓, 4,   Inflam↑, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 5,   NF-kB↑, 1,   p‑NF-kB↓, 1,   PSA↓, 1,   RANTES↓, 1,   TNF-α↓, 2,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,   e-pH↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AKR1C3/17β-HSD5/PGF Synthase↓, 1,   AR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 2,   ChemoSen↑, 12,   ChemoSen∅, 1,   CompStab↑, 1,   Dose?, 1,   Dose↓, 1,   Dose↑, 3,   Dose⇅, 1,   Dose↝, 24,   Dose∅, 1,   eff↓, 3,   eff↑, 13,   eff⇅, 1,   eff↝, 3,   eff∅, 1,   Half-Life↝, 1,   RadioS?, 2,   RadioS↓, 3,   RadioS↑, 85,   RadioS↝, 1,   RadioS∅, 1,   selectivity?, 1,   selectivity↓, 1,   selectivity↑, 19,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BloodF↑, 4,   CRP↓, 1,   EGFR↓, 1,   IL6↓, 2,   LDH↝, 1,   NLR↓, 1,   PSA↓, 1,   RBC↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   antiD↑, 1,   AntiTum↑, 3,   AntiTum∅, 1,   ANXi↓, 1,   chemoP↑, 5,   CR↑, 2,   fatigue↓, 1,   fatigue∅, 1,   hepatoP↑, 1,   hepatoP↝, 1,   LC↑, 2,   Mucositis↓, 2,   NKG2D↑, 1,   OS↑, 12,   Pain↓, 4,   QoL↑, 2,   radioP?, 1,   radioP↑, 21,   RenoP↑, 1,   Risk↓, 4,   toxicity↓, 2,   toxicity↝, 2,   TR↑, 1,   TumVol↓, 3,   TumW↓, 1,   Weight↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 1,  
Total Targets: 221

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 5,   Catalase↑, 3,   GPx↑, 3,   GPx1↑, 2,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 6,   GSH/GSSG↑, 1,   HO-1↑, 2,   Iron↓, 1,   lipid-P↓, 2,   MDA↓, 2,   MDA↑, 1,   NOX4↓, 1,   NRF2↓, 1,   NRF2↑, 5,   Prx↑, 1,   ROS↓, 22,   ROS∅, 1,   selenoP↑, 4,   SOD↑, 5,   SOD1↑, 1,   TAC↑, 1,   Trx↑, 1,   TrxR1↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compIII↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ATP↑, 1,   glucose↝, 1,   NADPH↑, 1,   NADPH∅, 1,   PGC1A↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Apoptosis↑, 1,   BAX↓, 1,   Bcl-2↑, 1,   Casp3↓, 3,   cl‑Casp3↓, 1,   p‑p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   p‑Akt↑, 1,   ERK↓, 1,   ERK↑, 1,   JNK↓, 1,   Mst1↓, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

p‑cJun↓, 1,   DNMTs↓, 1,   HDAC↑, 1,   other↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 7,   P53↓, 1,   SIRT6↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p300↓, 1,  

Migration(tgid=13) ⓘ

AP-1↓, 1,   Ca+2↓, 1,   Ca+2↑, 1,   Rho↓, 2,   ROCK1↓, 3,   TGF-β↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

VEGF↓, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   DR4↓, 1,   ICAM-1↓, 2,   IL10↑, 1,   IL1β↓, 2,   Inflam↓, 7,   MCP1/CCL2↓, 1,   NF-kB↓, 3,   p‑NF-kB↓, 1,   NLRP3↓, 1,   RANTES↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 8,   eff↑, 1,   eff↝, 1,   Half-Life↝, 1,   RadioS↑, 1,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BUN↓, 1,   LDH↓, 1,  

Functional Outcomes(tgid=23) ⓘ

cognitive↑, 2,   hepatoP↑, 1,   Learn↑, 1,   memory↑, 1,   OS↑, 1,   QoL↑, 1,   radioP↑, 24,   toxicity?, 1,   toxicity↓, 6,   toxicity↝, 1,   toxicity∅, 1,   Weight↑, 1,   Wound Healing↓, 1,   Wound Healing↑, 1,  
Total Targets: 100

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:201  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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