BBB Cancer Research Results

BBB, Blood-Brain Barrier Permeability: Click to Expand ⟱
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Type:
Blood-Brain Barrier(BBB) is a term often used regarding if a product has the ability to cross the BBB.
Scientific Papers found: Click to Expand⟱
5660- BNL,    Recent Progress on the Synergistic Antitumor Effect of a Borneol-Modified Nanocarrier Drug Delivery System
- Review, Var, NA
TumMeta↓, BBB↑, EPR↑, toxicity↓, BioAv↑, ChemoSen↑, eff↑, other↑, P-gp/ABCB1↓, MDR1↓, ROS↑, TumCCA↑, other↝, BioAv↓, DNAdam↑, BioEnh↑,
5665- BNL,    Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies
- in-vivo, Nor, NA
*BBB↑, eff↑,
5666- BNL,    Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider
- in-vivo, AD, NA
*BioAv↑, *eff↑, *Dose↝, *P-gp/ABCB1↓, *BBB↑, *NF-kB↓, *IL1β↓, *MMP9↓,
5667- BNL,    Preparation and evaluation of sustained-release solid dispersions co-loading gastrodin with borneol as an oral brain-targeting enhancer
- in-vivo, Nor, NA
*BioEnh↑, *eff↑, *BBB↑,
5668- BNL,    Anticancer effect of borneol: Mechanistic insights through literature review and in silico studies
- Review, Var, NA
AntiCan↑, Apoptosis↑, mtDam↑, ROS↑, mTORC1↓, EIF4E↓, Hif1a↓, NF-kB↓, STAT3↓, PI3K↓, Akt↓, ChemoSen↑, BioEnh↑, BioAv↑, BBB↑, toxicity↝,
5669- BNL,    Comparison of pharmacological activity and safety of different stereochemical configurations of borneol: L-borneol, D-borneol, and synthetic borneol
- Review, Nor, NA - Review, AD, NA - Review, Stroke, NA
*eff↑, *eff↑, *toxicity↝, *Inflam↓, *Bacteria↓, *neuroP↑, *Half-Life↝, *BBB↑, *BioEnh↑, *P-gp/ABCB1↓, *CYP3A4↓, *ROS↓, *neuroP↑,
5670- BNL,    Advances and perspectives on pharmacological activities and mechanisms of the monoterpene borneol
- Review, Stroke, NA
*TNF-α↓, *NF-kB↓, IL1β↓, MDA↓, BioEnh↑, BBB↑,
2772- Bos,    Mechanistic role of boswellic acids in Alzheimer’s disease: Emphasis on anti-inflammatory properties
- Review, AD, NA
*neuroP↑, *Inflam↓, *AChE↓, *Choline↑, *NRF2↑, *NF-kB↑, *BBB↑, *BioAv↑, *Half-Life↓, *Dose↝, *PGE2↓, *ROS↓, *cognitive↑, *antiOx↑, 5LO↓, *TNF-α↓, *IL6↓, *HO-1↑,
6542- BSB,    Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
- Review, Var, NA - Review, Park, NA - Review, AD, NA
AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE/β-secretase↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2/PTGS2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL6↑, *MMP13↓,
7832- CA,  CGA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BBB↑, *cognitive↑, *memory↑, *ROS↓, *p‑tau↓, *GSK‐3β↓, *MAPK↓, *NeuroI↓, *P53↓, *Casp3↓, *AChE↓, *APP↓, *BACE/β-secretase↓, *neuroP↑, *Dose↝,
4263- CA,    Neuroprotective Effects of Carnosic Acid: Insight into Its Mechanisms of Action
- Review, AD, NA
*neuroP↑, *ROS↓, *NO↓, *COX2/PTGS2↓, *MAPK↓, *NRF2↑, *GSH↑, *HO-1↑, *5HT↑, *BDNF↑, *PI3K↑, *Akt↑, *NF-kB↑, *BBB↑, *SIRT1↑, *memory↑, *Aβ↓, *NLRP3↓,
5864- CA,    Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1
- vitro+vivo, Stroke, PC12
*neuroP↑, *GSH↑, *HO-1↑, *NQO1↑, *NRF2↑, *ARE↑, *ROS↓, *BBB↑,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
5908- CAR,    Carvacrol improves neurological function by inhibiting TRPM7-mediated BBB disruption and hemorrhage after TBI
- in-vivo, Nor, NA
*TRPM7↓, *BBB↑, *motorD↑, *cognitive↑, *Dose↝, MMPs↓,
5901- CAR,    Neuroprotective role of carvacrol in ischemic brain injury: a systematic review of preclinical evidence and proposed TRPM7 involvement
- Review, Stroke, NA
*neuroP↑, *ROS↓, *MDA↓, *4-HNE↓, *SOD↑, *Catalase↑, *GPx↑, *Apoptosis↓, *cl‑Casp3↓, *TRPM7⇅, *BBB↓, *TRPM7↓,
5899- CAR,  TV,    Evaluation of the Interaction between Carvacrol and Thymol, Major Compounds of Ptychotis verticillata Essential Oil: Antioxidant, Anti-Inflammatory and Anticancer Activities against Breast Cancer Lines
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
Synergy↑, selectivity↑, BioAv↝, BBB↑, *toxicity↝, *antiOx↑, COX2/PTGS2↓, 5LO↓,
5927- CAR,    Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer’s and Parkinson’s Diseases
- Review, AD, NA - Review, Park, NA
*memory↑, *cognitive↑, *ROS↓, *Inflam↓, *motorD↑, *toxicity↓, *TRPV3↑, *other↓, *antiOx↑, *LDL↓, *COX2/PTGS2↓, *PPARα↑, *NO↓, *AChE↓, *eff↑, *SOD↑, *Catalase↑, *neuroP↑, *BioAv↝, *BBB↑, *BioAv↑, *CompStab↑,
5925- CAR,    Neuroprotective effects of carvacrol against Alzheimer’s disease and other neurodegenerative diseases: A review
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AChE↓, *BBB↑, *cardioP↑, *neuroP↑, *memory↑, *TAC↑, *ROS↓, *lipid-P↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *cognitive↑, *IL1β↓, *COX2/PTGS2↓, *TNF-α↓, *TLR4↓, *BDNF↑, *PKCδ↑, *5LO↓, *TRPM7↓, *GSH↑, *other↑, *Ferroptosis↓, *GPx4↑,
6253- CBC/D,    The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma
- Review, MB, NA
Gli1↓, Dose↝, HH↓, BBB↑,
6024- CGA,    Phase I study of chlorogenic acid injection for recurrent high-grade glioma with long-term follow-up
- Trial, GBM, NA
*toxicity↓, Half-Life↝, BBB↑,
6045- CGA,  SeNPs,    A Flower-like Brain Targeted Selenium Nanocluster Lowers the Chlorogenic Acid Dose for Ameliorating Cognitive Impairment in APP/PS1 Mice
- in-vivo, AD, NA
*neuroP↑, *BioAv↑, *GutMicro↑, *BBB↑, *Aβ↓, *glucose↝,
6034- CGA,    Effect and mechanism of chlorogenic acid on cognitive dysfunction in mice by lipopolysaccharide-induced neuroinflammation
- in-vivo, AD, NA
*cognitive↑, *TNF-α↓, *antiOx↑, *Inflam↓, *neuroP↑, *BBB↑, *eff↑, *memory↑, *AKT1↓, *MMP9↓, *MAPK↓,
4489- Chit,  SeNPs,    Inhibiting Metastasis and Improving Chemosensitivity via Chitosan-Coated Selenium Nanoparticles for Brain Cancer Therapy
- in-vitro, GBM, U87MG
TumCG↓, TumCMig↓, TumCI↓, ChemoSen↑, *BBB↑, toxicity↓, eff↑, eff↑, selectivity↑, MMP2↓, MMP9↓, EPR↑,
6107- Chol,    Choline supplements: An update
- Review, AD, NA
*memory↑, *cognitive↑, *Dose↝, *BBB↑, *cardioP↑, *ROS↓, *TMAO↑, *memory∅, *eff↑,
6112- Chol,    Trimethylamine N-oxide induced cognitive impairment through disruption of blood-brain barrier by inhibiting TGF-β pathway
- in-vivo, AD, NA
*TMAO↑, *cognitive↓, *BBB↝, *TJ↝,
6118- Chol,    Comparison of the effects of choline alphoscerate and citicoline in patients with dementia disorders: a systematic review and meta-analysis
- Review, AD, NA
*eff↑, *cognitive↑, *BBB↑, *Ach↑,
2781- CHr,  PBG,    Chrysin a promising anticancer agent: recent perspectives
- Review, Var, NA
PI3K↓, Akt↓, mTOR↓, MMP9↑, uPA↓, VEGF↓, AR↓, Casp↑, TumMeta↓, TumCCA↑, angioG↓, BioAv↓, *hepatoP↑, *neuroP↑, *SOD↑, *GPx↑, *ROS↓, *Inflam↓, *Catalase↑, *MDA↓, ROS↓, BBB↑, Half-Life↓, BioAv↑, ROS↑, Synergy↑, ROS↑, ROS↑, lipid-P↑, ER Stress↑, NOTCH1↑, NRF2↓, p‑FAK↓, Rho↓, PCNA↓, COX2/PTGS2↓, NF-kB↓, PDK1 / PDPK1↓, PDK3↑, GLUT1↓, Glycolysis↓, mt-ATP↓, Ki-67↓, cMyc↓, ROCK1↓, TOP1↓, TNF-α↓, IL1β↓, CycB/CCNB1↓, CDK2↓, EMT↓, STAT3↓, PD-L1↓, IL2↑,
3888- Cin,    Cinnamon, a promising prospect towards Alzheimer's disease
- Review, AD, NA
*tau↓, *Aβ↓, *neuroP↑, *ROS↓, *Inflam↓, *cardioP↑, *antiOx↑, *cognitive↑, *BBB↑, *p‑GSK‐3β↑, *AChE↓,
3891- Cin,    Identification of potential targets of cinnamon for treatment against Alzheimer's disease-related GABAergic synaptic dysfunction using network pharmacology
- Analysis, AD, NA
*BBB↑, *GABA↑, *Ingr↑, *antiOx↑, *Inflam↑, *Mood↑,
6155- CoQ10,    BPGbio Highlights Groundbreaking Data on BPM31510 for Mitochondrial Diseases at the Inaugural Mitochondrial Transplantation and Next Generation Therapeutics Conference
- Review, Var, NA
*CoQ10↑, *BBB↑, *ETC↑, eff↑,
3624- Cro,    Crocus Sativus L. (Saffron) in Alzheimer's Disease Treatment: Bioactive Effects on Cognitive Impairment
- Review, AD, NA
*AChE↓, *memory↑, *cognitive↑, *MDA↑, *Thiols↑, *GPx↑, *antiOx↑, *ROS↓, *Casp3↓, *neuroP↑, *SOD↑, *Ach↑, *ChAT↑, *BBB↑, *Aβ↓, *tau↓, *cognitive↑, *Inflam↓,
3857- CUR,    Alpha-Secretase ADAM10 Regulation: Insights into Alzheimer’s Disease Treatment
- Review, AD, NA
*Inflam↓, *antiOx↑, *IronCh↑, *BBB↑, *ADAM10↝,
3588- CUR,    The effect of curcumin on cognition in Alzheimer’s disease and healthy aging: A systematic review of pre-clinical and clinical studies
- Review, AD, NA
*cognitive↝, *BioAv↑, *Inflam↓, *COX2/PTGS2↓, *iNOS↓, *NF-kB↓, *TNF-α↓, *IL1↓, *IL2↓, *IL6↓, *IL8↓, *IL12↓, *ROS↓, *RNS↓, *antiOx↑, *BBB↑, *BioAv↓, *cognitive↑, *memory↑, *tau↓, *Synergy↑,
3581- CUR,    Curcumin Attenuated Neurotoxicity in Sporadic Animal Model of Alzheimer's Disease
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *BBB↑, *NRF2↑, *NF-kB↓, *cognitive↑, *ROS↓, *MDA↓, *SOD↑, *Catalase↑, *INF-γ↓, *IL4↓, *memory↑, *TNF-α↓, *IL1β↓,
3576- CUR,    Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer's Disease
- Review, AD, NA
*Inflam↓, *antiOx↑, *memory↑, *Aβ↓, *BBB↑, *cognitive↑, *tau↓, *LDL↓, *AChE↓, *IL1β↓, *IronCh↑, *neuroP↑, *BioAv↝, *PI3K↑, *Akt↑, *NRF2↑, *HO-1↑, *Ferritin↑, *HO-2↓, *ROS↓, *Ach↑, *GSH↑, *Bcl-2↑, *ChAT↑,
3574- CUR,    The effect of curcumin (turmeric) on Alzheimer's disease: An overview
- Review, AD, NA
*antiOx↑, *Inflam↓, *lipid-P↓, *cognitive↑, *memory↑, *Aβ↓, *COX2/PTGS2↓, *ROS↓, *AP-1↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *SOD↑, *GSH↑, *HO-1↑, *IronCh↑, *BioAv↓, *Half-Life↝, *Dose↝, *BBB↑, *BioAv↑, *toxicity∅, *Synergy↑,
3590- CUR,    The Holy Grail of Curcumin and its Efficacy in Various Diseases: Is Bioavailability Truly a Big Concern?
- Review, Var, NA - Review, AD, NA
*BioAv↓, *BioAv↑, Dose↑, *Dose↝, *BBB↑, *cognitive↑, *BioAv↑,
3751- CUR,  Gala,    A Novel Galantamine-Curcumin Hybrid as a Potential Multi-Target Agent against Neurodegenerative Disorders
- in-vivo, AD, NA
*AChE↓, *MDA↑, *GSH↑, *BBB↑,
6207- CUR,    Enhancing the Bioavailability and Bioactivity of Curcumin for Disease Prevention and Treatment
- Review, Var, NA - Review, AD, NA
*AntiCan↑, *Obesity↓, *Inflam↓, *lipid-P↓, *BioAv↓, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *mt-SOD↑, *MDA↓, *BBB↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroG↑, *memory↑, cardioP↑,
6259- Cyste,    Therapeutic Applications of Cysteamine and Cystamine in Neurodegenerative and Neuropsychiatric Diseases
- Review, AD, NA - Review, Park, NA
*ROS↓, *neuroP↑, *BDNF↑, *NRF2↑, *BBB↑, *HSPs↑, *GSH↑, *TG2/TGase↓, Aβ↓,
6676- Deg,    Deguelin’s Anticancer Bioactivity: Challenges and Opportunities in Medicinal Chemistry
- Review, Var, NA
TumCP↓, Apoptosis↑, NF-kB↓, Wnt↓, TumCCA↑, TumMeta↑, antiOx↑, Inflam↓, angioG↓, Half-Life↑, MMP2↓, MMP9↓, Casp9↑, Casp3↑, EMT↓, PTEN↑, ChemoSen↑, toxicity↑, *BBB↑,
6689- DFC,    Diclofenac-Induced Apoptosis in the Neuroblastoma Cell Line SH-SY5Y: Possible Involvement of the Mitochondrial Superoxide Dismutase
- in-vitro, neuroblastoma, SH-SY5Y
Apoptosis↑, mtDam↑, ROS↑, SOD2↓, MMP↓, Cyt‑c↑, Dose↝, BBB↑,
3721- EGb 761,    Ginkgo biloba Extract in Alzheimer’s Disease: From Action Mechanisms to Medical Practice
- Review, AD, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSR↑, *MMP↑, *Inflam↓, *Aβ↓, *memory↑, *Dose↝, *BBB↑, *neuroP↑,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, Var, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2/PTGS2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
6779- EGCG,    Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer's disease in a rat/mouse model: a systematic review
- Review, AD, NA
*BioAv↑, *ROS↓, *AChE↓, *Dose↝, *neuroP↑, *APP↓, *GSK‐3β↓, *PDK1 / PDPK1↓, *BBB↑, *memory↑,
4291- EGCG,    Structure-based discovery of small molecules that disaggregate Alzheimer’s disease tissue derived tau fibrils in vitro
- in-vitro, AD, NA
*tau↓, *BBB∅,
1516- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, Var, NA
*Dose∅, *Half-Life∅, *BioAv∅, *BBB↑, *toxicity∅, eff↓, Apoptosis↑, Casp3↑, Cyt‑c↑, cl‑PARP↑, DNMTs↓, Telomerase↓, angioG↓, Hif1a↓, NF-kB↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, IGF-1↓, H3↓, HDAC1↓, *LDH↓, *ROS↓,
6377- Eug,    Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review
- Review, Var, NA - Review, AD, NA
*Inflam↓, *Bacteria↓, ChemoSen↑, *selectivity↑, ROS⇅, TumCG↓, MMP↓, antiOx⇅, *antiOx↑, *BBB↑, *neuroP↑, *BDNF↑, *Aβ↓, *Ca+2↓, *5LO↓, *MAOA↓, other↑,
6848- EVO,    Evodiamine: A Extremely Potential Drug Development Candidate of Alkaloids from Evodia rutaecarpa
- Review, Nor, NA
AntiTum↑, cardioP↑, Inflam↓, TumCP↓, TumCCA↑, Apoptosis↑, TumAuto↑, BioAv↓, toxicity↑, NF-kB↓, MAPK↓, NOD1↓, p‑Akt↓, BAX↑, cl‑Casp3↑, γH2AX↑, cl‑PARP↑, ROS↑, BBB↑, neuroP↑, BioAv↑,
3717- FA,    Neuroprotective Properties of Ferulic Acid in Preclinical Models of Alzheimer's Disease: A Systematic Literature Review
- Review, AD, NA
*toxicity↓, *BBB↑, *Aβ↓, *antiOx↑, *Inflam↓, *neuroP↑,

Showing Research Papers: 51 to 100 of 238
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 238

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   antiOx⇅, 1,   Catalase↓, 2,   Catalase↑, 1,   GPx↑, 1,   GPx4↓, 1,   GSH↓, 3,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   Iron↑, 1,   Iron↝, 1,   lipid-P↑, 6,   MDA↓, 1,   MDA↑, 4,   NADH↓, 1,   NQO1↑, 1,   NRF2↓, 4,   NRF2↑, 3,   p66Shc↓, 1,   ROS↓, 5,   ROS↑, 31,   ROS⇅, 2,   mt-ROS↑, 3,   SOD↓, 2,   SOD↑, 1,   SOD2↓, 1,   Trx1↑, 1,   TrxR↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 1,   mitResp↓, 1,   mtDam↑, 3,   OCR↓, 2,   OCR↑, 1,   OXPHOS↑, 1,   mt-OXPHOS↑, 1,   PINK1↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 2,   AMPK↑, 2,   ATP↓, 1,   mt-ATP↓, 1,   ECAR↓, 1,   FASN↓, 1,   GlutMet↓, 1,   Glycolysis↓, 1,   GSK‐3β↑, 3,   lactateProd↓, 1,   NADPH↓, 1,   PDK1 / PDPK1↓, 1,   PDK3↑, 1,   SIRT1↓, 1,   SIRT1↑, 1,   TCA↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

APAF1↑, 1,   Apoptosis?, 1,   Apoptosis↓, 2,   Apoptosis↑, 22,   mt-Apoptosis↑, 1,   BAD↓, 1,   BAD↑, 1,   Bak↓, 1,   Bak↑, 2,   BAX↑, 10,   Bax:Bcl2↑, 1,   Bcl-2↓, 11,   Bcl-xL↓, 4,   BID↓, 1,   BID↑, 2,   BNIP3↑, 1,   Casp↑, 4,   cl‑Casp↑, 1,   Casp12↑, 1,   Casp3↓, 1,   Casp3↑, 17,   cl‑Casp3↑, 2,   proCasp3↓, 1,   Casp6↑, 1,   Casp7↑, 1,   Casp8↑, 7,   Casp9↑, 13,   cl‑Casp9↑, 1,   proCasp9↓, 1,   cFLIP↓, 2,   Cyt‑c↑, 17,   DR5↑, 4,   Fas↑, 2,   Ferroptosis↑, 2,   GranB/GZMB↝, 1,   ICD↑, 1,   iNOS↓, 1,   Mcl-1↑, 1,   MDM2↓, 1,   MOMP↑, 2,   p38↑, 2,   p‑p38↓, 1,   Perforin↝, 1,   survivin↓, 3,   TumCD↑, 1,   XIAP↓, 2,   XIAP↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 18,   p‑Akt↓, 5,   BRAF↓, 1,   cSrc↓, 1,   DYRK1B↓, 1,   EF-1α↓, 1,   EGFR↓, 3,   EGFR↑, 1,   p‑EGFR↓, 1,   ERK↓, 3,   p‑ERK↓, 2,   FOXD3↑, 1,   HER2/EBBR2↓, 1,   HGF/c-Met↓, 1,   IKKα↓, 1,   JAK1↓, 1,   JAK2↓, 3,   JNK↓, 1,   JNK↑, 2,   MAPK↓, 5,   MAPK↑, 1,   MEK↓, 1,   mTOR↓, 8,   p‑mTOR↓, 1,   PI3K↓, 12,   PTEN↑, 6,   c-Raf↓, 1,   RAS↓, 3,   Sp1/3/4↓, 1,   STAT3↓, 11,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cJun↑, 1,   cMyc↓, 3,   DNMTs↓, 2,   FOXM1↓, 1,   FOXO1↑, 1,   FOXO3↓, 1,   H3↓, 1,   H3↑, 1,   H4↑, 1,   HATs↑, 1,   HDAC↓, 2,   HDAC1↓, 1,   HIST1H3B?, 1,   miR-19b↓, 1,   Myc↓, 1,   OCT4↓, 1,   other↑, 2,   other↝, 3,   SOX2↓, 1,   SOX4↓, 1,   tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 1,   cl‑CHOP/DDIT3↑, 1,   ER Stress↑, 5,   GRP78/BiP↑, 1,   HSP27↓, 1,   HSP90↓, 1,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   ATG7↑, 1,   Beclin-1/ATG6↑, 2,   CTSK↓, 1,   LC3II↑, 2,   MitoP↑, 1,   PARK2↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 6,   DNArepair↓, 1,   hTERT/TERT↓, 2,   P53?, 1,   P53↑, 11,   P53↝, 1,   PARP↑, 2,   cl‑PARP↑, 9,   PARP1↑, 1,   PCNA↓, 2,   Telomerase↓, 3,   TOP1↓, 3,   TOP2↓, 1,   TOP2↑, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK1↑, 1,   CDK2↓, 5,   CDK4↓, 2,   CDK6↓, 1,   CHK1↓, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 4,   CycB/CCNB1↑, 2,   cycD1/CCND1↓, 3,   cycD1/CCND1↑, 1,   Ki-67↓, 2,   mitA↑, 1,   P21?, 1,   P21↑, 2,   p27/CDKN1B↑, 1,   p‑RB1↓, 1,   TubPol↓, 1,   TumCCA↓, 1,   TumCCA↑, 17,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP7/OP1↓, 1,   BMPs↑, 1,   CD133↓, 2,   cFos↓, 1,   CSCs↓, 2,   Diff↑, 1,   EIF4E↓, 1,   FGF↓, 1,   Gli1↓, 3,   HH↓, 3,   IGF-1↓, 1,   Ki-67↓, 2,   mTORC1↓, 2,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   NOTCH1↓, 1,   NOTCH1↑, 1,   NOTCH3↓, 1,   PTCH2↓, 1,   Shh↓, 1,   TumCG↓, 13,   TumCP↓, 14,   TumCP↑, 2,   Wnt↓, 6,  

Migration(tgid=13) ⓘ

Ca+2↑, 2,   Ca+2↝, 1,   E-cadherin↑, 3,   EMT↓, 8,   FAK↓, 1,   p‑FAK↓, 2,   fascin↓, 1,   MMP2↓, 9,   MMP7↓, 1,   MMP9↓, 11,   MMP9↑, 2,   MMPs↓, 6,   N-cadherin↓, 2,   Rac1↓, 1,   Rho↓, 1,   Rho↑, 1,   ROCK1↓, 1,   ROCK1↑, 1,   Snail↓, 2,   TGF-β↓, 1,   TIMP1↓, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TRIB3↑, 1,   TumCI↓, 7,   TumCMig↓, 7,   TumMeta?, 1,   TumMeta↓, 10,   TumMeta↑, 2,   Twist↓, 3,   uPA↓, 4,   Vim↓, 2,   Zeb1↓, 1,   β-catenin/ZEB1↓, 6,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 16,   HIF-1↓, 1,   Hif1a↓, 10,   Hif1a↑, 1,   NO↝, 1,   VCAM-1↓, 1,   VEGF↓, 14,   VEGFR2/KDR/Flk1↓, 4,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 35,   BBB↝, 1,   BBB∅, 2,   EPR↑, 5,   EPR↝, 1,   GLUT1↓, 1,   MMP↓, 15,   MPT↑, 1,   TRPV1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   COX2/PTGS2↓, 7,   CXCR2↓, 1,   CXCR4↓, 1,   DR4↑, 1,   ICAM-1↓, 2,   IL1↓, 1,   IL1↑, 1,   IL10↓, 1,   IL1β↓, 7,   IL2↑, 1,   IL6↓, 4,   IL8↓, 1,   IL8↑, 1,   Imm↑, 2,   Inflam↓, 7,   M1↑, 1,   M2 MC↑, 1,   NF-kB↓, 20,   NF-kB↑, 1,   NOD1↓, 1,   p65↓, 1,   PD-L1↓, 2,   PGE2↓, 3,   TNF-α↓, 7,  

Synaptic & Neurotransmission(tgid=18) ⓘ

SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACTH↓, 1,   ADRB2↓, 1,   AR↓, 1,   GR↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 10,   BioAv↑, 11,   BioAv↝, 6,   BioEnh↑, 4,   ChemoSen?, 1,   ChemoSen↑, 25,   DDS↑, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 9,   eff↓, 4,   eff↑, 21,   eff↝, 1,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 7,   MDR1↓, 3,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 6,   RadioS?, 1,   RadioS↑, 10,   selectivity↑, 8,   Synergy↑, 9,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BRAF↓, 1,   CEA↓, 1,   EGFR↓, 3,   EGFR↑, 1,   p‑EGFR↓, 1,   FOXM1↓, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 2,   IL6↓, 4,   Myc↓, 1,   NOS2↑, 1,   PD-L1↓, 2,   TF-Ag↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 7,   AntiTum↑, 4,   cardioP↑, 4,   chemoP↑, 7,   chemoPv↑, 3,   cognitive?, 1,   cognitive↑, 2,   hepatoP↑, 1,   memory↑, 1,   neuroP↓, 1,   neuroP↑, 3,   Obesity↓, 1,   OS↑, 7,   Pain↓, 1,   QoL↑, 2,   RenoP↑, 1,   Risk↑, 1,   toxicity↓, 5,   toxicity↑, 2,   toxicity↝, 3,   toxicity∅, 2,   TumVol↓, 3,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   GutMicro↑, 1,   GutMicro↝, 1,  
Total Targets: 381

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,   NA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 2,   antiOx↓, 3,   antiOx↑, 81,   mt-antiOx↑, 1,   ARE↑, 2,   Catalase↓, 1,   Catalase↑, 25,   Copper↓, 1,   CoQ10↑, 1,   Fenton↓, 2,   GPx↑, 18,   GPx4↑, 3,   GSH↑, 43,   GSR↓, 1,   GSR↑, 10,   GSTs↓, 3,   GSTs↑, 5,   H2O2↓, 2,   H2O2∅, 1,   HDL↑, 1,   HO-1↑, 25,   HO-2↓, 1,   hyperG↓, 1,   Iron↓, 4,   Keap1↓, 2,   Keap1↑, 2,   lipid-P↓, 31,   mt-lipid-P↓, 1,   MDA↓, 21,   MDA↑, 3,   MPO↓, 5,   NQO1↑, 7,   NQO1↝, 1,   NRF2↑, 50,   RNS↓, 4,   ROS?, 1,   ROS↓, 116,   ROS↑, 1,   SOD↓, 1,   SOD↑, 43,   mt-SOD↑, 1,   SOD1↑, 2,   SOD2↑, 1,   TAC↑, 4,   TBARS↓, 4,   Thiols↑, 1,   Trx↑, 1,   Trx1↑, 1,   TrxR↑, 1,   TrxR1↑, 1,   uricA↓, 1,   VitC↑, 3,   VitE↑, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   IronCh↑, 16,   Mets↝, 1,   TfR1/CD71↓, 2,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compII↑, 1,   compIII↑, 1,   compIV↑, 3,   compV↑, 1,   ETC↑, 3,   FIS1↓, 1,   mitResp↑, 1,   mtDam↓, 2,   OCR↑, 4,   PDH↑, 1,   PGC-1α↑, 5,   SIRT3↑, 4,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   5LO↓, 2,   ACC↑, 1,   Acetyl-CoA↑, 1,   ACSL4↓, 2,   adiP↑, 2,   ALAT↓, 5,   AMPK↑, 10,   p‑AMPK↑, 1,   ATP↑, 10,   cAMP↑, 2,   DHA↑, 1,   ECAR↓, 1,   FAO↓, 1,   G6PD↑, 1,   glucose↓, 1,   glucose↑, 1,   glucose↝, 2,   GlucoseCon↑, 5,   Glycolysis↓, 1,   GSK‐3β↓, 16,   GSK‐3β↑, 1,   p‑GSK‐3β↑, 3,   H2S↑, 1,   LDL↓, 5,   NADH:NAD↑, 1,   NADPH↓, 2,   NADPH↑, 2,   PDK1 / PDPK1↓, 1,   PDKs↓, 1,   SIRT1↓, 1,   SIRT1↑, 8,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 14,   ASC↓, 1,   BAX↓, 6,   BAX↑, 1,   Bax:Bcl2↓, 1,   Bcl-2↓, 3,   Bcl-2↑, 4,   Casp↓, 1,   Casp1↓, 1,   Casp3↓, 13,   Casp3↑, 1,   cl‑Casp3↓, 1,   Casp6↓, 1,   Casp9↓, 4,   Casp9↑, 1,   Cyt‑c↓, 2,   Cyt‑c↑, 1,   Cyt‑c∅, 1,   Ferroptosis↓, 5,   iNOS↓, 20,   necrosis↓, 1,   p38↓, 1,   p38↑, 1,   p‑p38↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 10,   p‑Akt↑, 3,   AKT1↓, 1,   CREB↑, 3,   p‑CREB↑, 3,   ERK↓, 4,   ERK↑, 3,   p‑ERK↓, 1,   p‑ERK↑, 2,   IGF-1R↓, 1,   JAK↓, 1,   JNK↓, 3,   p‑JNK↓, 2,   MAPK↓, 9,   MAPK↑, 3,   mTOR↓, 5,   mTOR↑, 2,   p‑mTOR↓, 1,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 4,   PI3K↑, 7,   PKCδ?, 1,   PKCδ↑, 3,   PTEN↓, 3,   PTP1B↓, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   cJun↓, 1,   FOXO↑, 1,   FOXO3↑, 1,   H3↑, 1,   H4↑, 1,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 1,   MEF2D↑, 1,   other?, 2,   other↓, 4,   other↑, 8,   other↝, 7,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   ER Stress↓, 3,   GRP78/BiP↓, 3,   GRP78/BiP↑, 1,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↑, 1,   HSPs↑, 2,   IRE1↓, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

autophagy↓, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 2,   CTSZ↓, 1,   MitoP↑, 3,   p62↓, 1,   p62↑, 1,   PARK2↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 4,   DNArepair↑, 1,   P53↓, 2,   SIRT6↑, 1,   γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cellSen↝, 1,   E2Fs↑, 1,   Ki-67↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Choline↑, 1,   GH↑, 1,   Ki-67↑, 1,   neuroG↑, 8,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 3,   AP-1↓, 3,   BACH1↓, 1,   Ca+2?, 1,   Ca+2↓, 5,   Ca+2↑, 1,   Ca+2↝, 1,   Cartilage↑, 1,   MMP13↓, 1,   MMP2↓, 3,   MMP9↓, 9,   MMPs↓, 1,   N-cadherin↑, 1,   NFAT↓, 1,   Rho↓, 1,   p‑T-cadherin↓, 1,   TG2/TGase↓, 1,   TGF-β↓, 2,   TGF-β1↑, 1,   TregCell↑, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   CD31/PECAM-1↑, 1,   eNOS↑, 1,   Hif1a↑, 1,   NO↓, 15,   NO↑, 1,   VCAM-1↓, 6,   VEGF↑, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 3,   BBB↓, 10,   BBB↑, 171,   BBB↝, 14,   BBB∅, 4,   CellMemb↑, 1,   CLDN1↝, 1,   CLDN4↑, 1,   CLDN5↑, 1,   CX43/GJA1↑, 1,   EPR↑, 1,   GastroP↑, 2,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↑, 3,   memfluid↑, 1,   MMP↑, 14,   MUC19↓, 1,   MUC2↓, 1,   OCLN↑, 2,   THBD↑, 1,   TJ↑, 2,   TJ↝, 1,   TRPM7↓, 3,   TRPM7⇅, 1,   TRPV1↑, 1,   TRPV3↑, 1,   ZO-1↑, 4,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   CD4+↑, 1,   CD8+↑, 1,   COX1↓, 1,   COX2/PTGS2↓, 28,   HMGB1↓, 2,   ICAM-1↓, 3,   IFN-γ↓, 1,   IL1↓, 1,   IL10↓, 1,   IL10↑, 2,   IL12↓, 1,   IL17↓, 1,   IL1α↓, 1,   IL1β↓, 33,   IL2↓, 3,   IL23↓, 1,   IL33↓, 1,   IL4↓, 4,   IL6↓, 28,   IL6↑, 2,   IL8↓, 5,   Imm↑, 3,   INF-γ↓, 2,   INF-γ↑, 1,   Inflam↓, 96,   Inflam↑, 2,   IRF3↓, 1,   MCP1/CCL2↓, 4,   MIP‑1α/CCL3↓, 1,   MyD88↓, 2,   NeuroI↓, 5,   NF-kB↓, 36,   NF-kB↑, 2,   p‑NF-kB↓, 3,   NLRP3↓, 14,   p65↓, 1,   PGE2↓, 7,   RAGE↓, 1,   RANTES↓, 2,   TLR2↓, 1,   TLR4↓, 8,   TNF-α↓, 45,   TRAF6↓, 1,   TRIF↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 8,   Ach↑, 10,   AChE↓, 35,   AChE↑, 1,   ADAM10↑, 2,   ADAM10↝, 1,   BChE↓, 7,   BDNF↑, 26,   BrainVol↑, 1,   CARTPT↑, 1,   ChAT↑, 7,   GABA↓, 1,   GABA↑, 3,   MAOA↓, 5,   MAOB↓, 1,   monoA↑, 1,   NGF↑, 3,   PSD95↑, 3,   SNAP25↑, 2,   TrkB↑, 4,   TrkB↝, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   APOE4↓, 1,   APP↓, 8,   cl‑APP↑, 1,   Aβ↓, 76,   Aβ42↓, 3,   BACE/β-secretase↓, 16,   BACE/β-secretase↝, 1,   PSEN1/PS1↑, 1,   tau↓, 18,   p‑tau↓, 18,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER(estro)↓, 1,   PPARα↑, 1,   PPARγ↑, 6,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv↓, 30,   BioAv↑, 52,   BioAv⇅, 1,   BioAv↝, 20,   BioAv∅, 1,   BioEnh↑, 4,   ChemoSen↑, 1,   CompStab↑, 1,   CYP3A2↓, 1,   CYP3A4↓, 1,   DDS↑, 2,   Dose?, 1,   Dose↓, 1,   Dose↑, 3,   Dose↝, 33,   Dose∅, 1,   eff↓, 3,   eff↑, 35,   eff↝, 1,   Half-Life↓, 7,   Half-Life↑, 4,   Half-Life↝, 14,   Half-Life∅, 1,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 6,   P450↓, 1,   selectivity↑, 1,   Synergy↑, 17,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 5,   anemia↓, 1,   AST↓, 6,   BG↓, 1,   BloodF↑, 3,   BP↓, 8,   BP↝, 1,   BP∅, 1,   creat↓, 2,   CRP↓, 1,   Ferritin↓, 1,   Ferritin↑, 1,   HemoG↑, 1,   IL6↓, 28,   IL6↑, 2,   LDH↓, 3,   NOS2↓, 1,   RAGE↓, 1,   RBC↑, 1,   TC↓, 1,   TMAO↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   antiAll↑, 3,   AntiCan↑, 9,   AntiDiabetic↑, 4,   AntiMyl↑, 1,   AntiTum↑, 1,   Bone Healing↑, 1,   cardioP↑, 17,   chemoP↑, 1,   cognitive↓, 1,   cognitive↑, 86,   cognitive↝, 1,   cognitive∅, 2,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 2,   hepatoP↑, 10,   Learn↑, 4,   memory↓, 1,   memory↑, 68,   memory∅, 1,   Mood↑, 6,   motorD↑, 15,   Mucositis↓, 1,   neuroP?, 1,   neuroP↑, 110,   NP/CIPN↓, 1,   Obesity↓, 3,   OS↑, 2,   Pain↓, 3,   radioP↑, 1,   RenoP↓, 1,   RenoP↑, 5,   Risk↓, 3,   Sleep↑, 5,   Strength↑, 5,   Stress↓, 3,   Stroke↓, 9,   toxicity↓, 17,   toxicity↑, 2,   toxicity⇅, 1,   toxicity↝, 3,   toxicity∅, 6,   Weight↓, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 6,   AntiFungal↑, 4,   AntiP↑, 2,   AntiViral↑, 4,   Bacteria↓, 7,   GutMicro↑, 18,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 1,   Ingr↝, 1,  
Total Targets: 449

Scientific Paper Hit Count for: BBB, Blood-Brain Barrier Permeability
14 Selenium NanoParticles
13 Alpha-Lipoic-Acid
11 borneol
10 Curcumin
10 Hydrogen Gas
7 Honokiol
6 Luteolin
6 Methylene blue
6 Mushroom Lion’s Mane, Hericium erinaceus
6 Urolithin
5 Chlorogenic acid
5 Carvacrol
5 EGCG (Epigallocatechin Gallate)
5 Pterostilbene
4 Silver-NanoParticles
4 Berberine
4 Mung Bean Sprouts
4 Ferulic acid
4 Lycopene
4 Quercetin
4 Resveratrol
3 5-Hydroxytryptophan
3 Apigenin (mainly Parsley)
3 Bacopa monnieri
3 Choline
3 Gamma-aminobutyric acid
3 Rosmarinic acid
3 Licochalcone A
3 Rutin
3 Sulforaphane (mainly Broccoli)
2 almonertinib
2 Baicalein
2 beta-carotene(VitA)
2 Caffeic acid
2 Carnosic acid
2 Cinnamon
2 Fisetin
2 Isobavachalcone
2 Isoliquiritigenin
2 Ivermectin
2 Lactoferrin/Talactoferrin
2 Matrine
2 Melatonin
2 Vitamin B3,Niacin
2 S-adenosyl-L-methionine
2 Silymarin (Milk Thistle) silibinin
2 Thymoquinone
2 Turmerones
2 Vitamin B5,Pantothenic Acid
1 1,8-Cineole
1 acetaminophen
1 Anthocyanins
1 Allicin (mainly Garlic)
1 Acetyl-l-carnitine
1 Bevacizumab (brand Avastin)
1 Aromatherapy
1 Ashwagandha(Withaferin A)
1 Astaxanthin
1 Baicalin
1 Beta-Caryophyllene
1 Betulinic acid
1 Brucea javanica
1 Boswellia (frankincense)
1 α-Bisabolol / Chamomile oil
1 Capsaicin
1 Thymol-Thymus vulgaris
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chitosan
1 Chrysin
1 Propolis -bee glue
1 Coenzyme Q10
1 Crocetin
1 Galantamine
1 Cysteamine
1 Deguelin
1 Diclofenac
1 Ginkgo biloba-EGb 761
1 Eugenol
1 Evodiamine
1 Fucoidan
1 Gambogic Acid
1 Geraniol
1 Glabrescione B
1 Gold NanoParticles
1 Hydroxycinnamic-acid
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Inositol
1 isoflavones
1 isoorientin
1 isoquercitrin
1 Magnolol
1 Isovitexin
1 Vitexin
1 mebendazole
1 MCT oil
1 Magnetic Fields
1 Mangiferin
1 Moringa oleifera
1 Methylsulfonylmethane
1 L-Theanine
1 Myricetin
1 Myrrh
1 nicotinamide adenine dinucleotide
1 Nimbolide
1 Olive Oil
1 HydroxyTyrosol
1 Oleuropein
1 Protocatechuic acid
1 Propranolol
1 Rauwolfia serpentina/Indian Snakeroot
1 Metformin
1 Taurine
1 Vitamin C (Ascorbic Acid)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1123  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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