RenoP Cancer Research Results

RenoP, K,Renoprotection/Nephroprotective: Click to Expand ⟱
Source:
Type:
Protects kidneys
-Same as nephroprotective
Opposite is : Nephrotoxicity is toxicity in the kidneys
Scientific Papers found: Click to Expand⟱
6885- FA,    Mitigation of renal toxicity induced by paraquat using ferulic acid: Role of inflammatory pathways
- in-vivo, Nor, NA
*Dose↝, *TAC↑, *MDA↓, *RenoP↑, *PI3K↓, *Akt↓, *ROS↓, *Inflam↓, PPARγ↝, *NF-kB↓, *IL6↓, *TNF-α↓, *iNOS↓, *ALAT↓, *AST↓, *Urea↓, *Catalase↑, *SOD↑, *GPx↑, *GSH↑,
3714- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK↓, *p38↓, *JNK↓, *IL6↓, *IL8↓, *hepatoP↑, *RenoP↑, *Catalase↑, *PPARγ↑, *ROS↓, *Fenton↓, *IronCh↑, *SOD↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ARE↑, *Bil↑, *radioP↑, *GCLC↑, *GCLM↑, *NQO1↑, *Half-Life↝, *GutMicro↑, *Aβ↓, *BDNF↑, *Ca+2↓, *lipid-P↓, *PGE2↓, *cognitive↑, *ChAT↑, *memory↑, *Dose↝, *toxicity↓,
2827- FIS,    The Potential Role of Fisetin, a Flavonoid in Cancer Prevention and Treatment
- Review, Var, NA
*antiOx↑, *Inflam↓, neuroP↑, hepatoP↑, RenoP↑, cycD1/CCND1↓, TumCCA↑, MMPs↓, VEGF↓, MAPK↓, NF-kB↓, angioG↓, Beclin-1/ATG6↑, LC3s↑, ATG5↑, Bcl-2↓, BAX↑, Casp↑, TNF-α↓, Half-Life↓, MMP↓, mt-ROS↑, cl‑PARP↑, CDK2↓, CDK4↓, Cyt‑c↑, Diablo↑, DR5↑, Fas↑, PCNA↓, Ki-67↓, p‑H3↓, chemoP↑, Ca+2↑, Dose↝, CDC25↓, CDC2↓, CHK1↑, Chk2↑, ATM↑, PCK1↓, RAS↓, p‑p38↓, Rho↓, uPA↓, MMP7↓, MMP13↓, GSK‐3β↑, E-cadherin↑, survivin↓, VEGFR2/KDR/Flk1↓, IAP2/BIRC3↓, STAT3↓, JAK1↓, mTORC1↓, mTORC2↓, NRF2↑,
2828- FIS,    Fisetin, a Potent Anticancer Flavonol Exhibiting Cytotoxic Activity against Neoplastic Malignant Cells and Cancerous Conditions: A Scoping, Comprehensive Review
- Review, Var, NA
*neuroP↑, *antiOx↑, *Inflam↓, RenoP↑, COX2/PTGS2↓, Wnt↓, EGFR↓, NF-kB↓, Casp3↑, Ca+2↑, Casp8↑, TumCCA↑, CDK1↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, *P53↓, *P21↓, *p16↓, mTORC1↓, mTORC2↓, P53↑, P21↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, CDK4↓, BAX↑, Bcl-2↓, PCNA↓, HER2/EBBR2↓, Cyt‑c↑, MMP↓, cl‑Casp9↑, MMP2↓, MMP9↓, cl‑PARP↑, uPA↓, DR4↑, DR5↑, ROS↓, AIF↑, CDC25↓, Dose↑, CHOP/DDIT3↑, ROS↑, cMyc↓, cardioP↑,
7012- Fuc,    Fucoidan: A promising natural therapeutic agent for protecting human kidney health
- Review, EC, NA
*RenoP↑, *Inflam↓, *antiOx↑, *ROS↓, *BloodF↑, *diuretic↑, *BioAv↓, *BioAv↑, *MAPK↓, *ERK↑, *NLRP3↓, *NRF2↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *lipid-P↓, *DNAdam↓, *Fibrosis↓, *JAK2↓, *STAT3↓, *uricA↓, *COL1↓, *α-SMA↓, *SIRT1↑, *HO-1↑, *GLP-1R↑, *HMGB1↓, *RAGE↓, *NF-kB↓, *TGF-β1↓, *PI3K↓, *Akt↓, *GutMicro↑, *SCFAs↑, *Buty↑, *IBI↑, *TJ↑, *Dose↝,
7207- GBE,    The molecular mechanisms of ginkgo (Ginkgo biloba) activity in signaling pathways: A comprehensive review
- Review, AD, NA
*Inflam↓, *Apoptosis↓, *neuroP↑, *cardioP↑, *hepatoP↑, *AntiViral↑, *Bacteria↓, *RenoP↑, *ROS↓, *NADPH↓, *MAPK↓, *ERK↓, *JNK↓, *AP-1↓, *cAMP↑, *STAT5↓, *AMPK↑,
7112- GEO2,    Hazard assessment of germanium supplements
- Review, Var, NA
toxicity↝, RenoP↓, NP/CIPN↑, Dose↝,
7331- GSE,    Protection against drug- and chemical-induced multiorgan toxicity by a novel IH636 grape seed proanthocyanidin extract
- in-vivo, Nor, NA
*ROS↓, TumCD↑, *RenoP↑,
7330- GSE,    Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention
- Review, Var, NA
*BioAv↑, *ROS↓, AntiCan↑, selectivity↑, RenoP↑, *hepatoP↑, *DNAdam↓, *Stroke↓, *Bcl-2↑, cMyc↓,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, Synergy↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑, *antiAll↑,
7483- H2,  Cisplatin,    Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism
- in-vivo, Nor, HK-2
RenoP↑, BHB↑, HMGCS2↑, chemoP↑, *IL2↓, *IL6↓, *MCP1/CCL2↓, *TNF-α↓, *KeyT↝, *Inflam↓, *ROS↓, *MMP↑, *ATP↑, *MFN2↑, *PGC-1α↑, *BUN↓, *creat↓,
7490- H2,    Long-term administration of hydrogen-rich water enhances quality of life in diabetic rats and reduces renal neoplasm incidence through modulation of inflammatory and metabolic pathways
- in-vivo, Diabetic, NA
*BG↓, *AntiDiabetic↑, *BMD↑, *hepatoP↑, *RenoP↑, *QoL↑,
2516- H2,    Hydrogen Gas in Cancer Treatment
- Review, Var, NA
*Half-Life↓, *ROS↓, *selectivity↑, *SOD↑, *HO-1↑, *NRF2↑, *chemoP↑, *radioP↑, ROS↑, *Inflam↓, eff↑, *TNF-α↓, *IL6↓, *cl‑Casp8↑, *Bax:Bcl2↓, *Apoptosis↓, *cardioP↑, *hepatoP↑, *RenoP↑, *chemoP↑, eff↝, chemoP↑, radioP↑, Synergy↑, TumCG↓, Ki-67↓, VEGF↓, selectivity↑,
2507- H2,    Hydrogen protects against chronic intermittent hypoxia induced renal dysfunction by promoting autophagy and alleviating apoptosis
- in-vivo, Nor, NA
*RenoP↑, *ROS↓, *Apoptosis↓, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *Beclin-1/ATG6↑, *p62↓, *mTOR↓,
7366- HibSad,    Does consumption of an aqueous extract of Hibscus sabdariffa affect renal function in subjects with mild to moderate hypertension?
- Human, Nor, NA
*creat↓, *RenoP↑,
7361- HibSad,    Hibiscus sabdariffa L. - a phytochemical and pharmacological review
- Review, Var, NA
*Bacteria↓, *hepatoP↑, *diuretic↑, *LDL↓, *antiOx↑, *ACE/ACE1↓, *Ca+2↝, *toxicity↓, *ROS↓, *RenoP↑,
2868- HNK,    Honokiol: A review of its pharmacological potential and therapeutic insights
- Review, Var, NA - Review, Sepsis, NA
*P-gp/ABCB1↓, *ROS↓, *TNF-α↓, *IL10↓, *IL6↓, eIF2α↑, CHOP/DDIT3↑, GRP78/BiP↑, BAX↑, cl‑Casp9↑, p‑PERK↑, ER Stress↑, Apoptosis↑, MMPs↓, cFLIP↓, CXCR4↓, Twist↓, HDAC↓, BMPs↑, p‑STAT3↓, mTOR↓, EGFR↓, NF-kB↓, Shh↓, VEGF↓, tumCV↓, TumCMig↓, TumCI↓, ERK↓, Akt↓, Bcl-2↓, Nestin↓, CD133↓, p‑cMET↑, RAS↑, chemoP↑, *NRF2↑, *NADPH↓, *p‑Rac1↓, *ROS↓, *IKKα↑, *NF-kB↓, *COX2/PTGS2↓, *PGE2↓, *Casp3↓, *hepatoP↑, *antiOx↑, *GSH↑, *Catalase↑, *RenoP↑, *ALP↓, *AST↓, *ALAT↓, *neuroP↑, *cardioP↑, *HO-1↑, *Inflam↓,
7567- HYP,    Hyperoside: A review on its sources, biological activities, and molecular mechanisms
- Review, Var, NA
*AntiCan↑, *Bacteria↓, *AntiViral↑, *antiD↓, *RenoP↑, *hepatoP↑, *eff↑, *Sepsis↓, *AntiArt↑, *Stroke↓, TumCMig↓, TumCI↓, MTA1↓, TIMP2↓, MMP2↓, MMP↓, Cyt‑c↑, Akt↓, mTOR↓, P70S6K↓, TumAuto↑, PD-L1↓, TNF-α↓, IL1β↓, IL6↓, IL8↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Bak↑, VEGF↓, Casp3↑, Casp8↑, P53↑, GSH↓, SOD↓, Catalase↓, TAC↓, XIAP↓, ROS↓, NF-kB↓, TLR4↓, P-gp/ABCB1↓, LRP1↓, Fas↑, p27/CDKN1B↑, *cardioP↑, *AntiThr↑, *PAI-1/SERPINE1↓, *BUN↓, *ALAT↓, *AST↓, *neuroP?,
7560- HYP,    Hyperoside: A Review of Its Structure, Synthesis, Pharmacology, Pharmacokinetics and Toxicity
- Review, Nor, NA - Review, AD, NA
*RenoP↓, Casp3↑, Casp8↑, MDA↑, GSH↓, SOD↓, Catalase↓, VEGF↓, Bcl-2↓, TumCG↓, p‑Akt↓, PI3K↓, TumCCA↑, TumCP↓, BMP7/OP1↓, *ZO-1↑, *BBB↝, *p‑Akt↑, *GSK‐3β↑, *SOD↑, *Catalase↑, *GSH↑, *SIRT1↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *ROS↓, *MDA↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BDNF↑, *TrkB↑, *NGF↑, *Apoptosis↓, *cardioP↑, *AST↓, *hepatoP↑, *AST↓, *ALAT↓, *MDA↓, *BACH1↓, *neuroP↑, *Stroke↓, *ICAM-1↓, *VCAM-1↓, *TLR4↓, *COX2/PTGS2↓, *RenoP↑, *NLRP3↓, *Casp1↓, *ASC↓, *BioAv↓, *BioAv↑, *toxicity↓,
7699- IP6,    IP6: From Seeds to Science—A Natural Compound’s Path to Clinical Promise
- Review, Var, NA
*Iron∅, ChemoSen↑, *cardioP↑, neuroP↑, IronCh∅, P21↓, p27/CDKN1B↓, p‑pRB↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TumW↓, TumCI↓, TumMeta↓, Imm↑, Diff↑, selectivity↑, toxicity↓, RenoP↑, QoL↑,
7760- ISL,    Pharmacological Potentials and Delivery Strategies of Isoliquiritigenin: Challenges and Advances in Enhancing Bioavailability
- Review, Nor, NA
*BioAv↓, GlucoseCon↓, LDH↓, PDK1 / PDPK1↓, Glycolysis↓, mt-OXPHOS↓, Bax:Bcl2↓, cl‑Casp3↑, cl‑Casp9↑, Apoptosis↑, Hif1a↓, ROS↑, *AntiDiabetic↑, *cardioP↑, *RenoP↑, *ROS↓, *NF-kB↓, *NLRP3↓, *Pyro↓, *antiPs↑, *IL6↓, *IL8↓, CompStab↑, BioAv↑, BioAv↑,
7765- ISL,    Isoliquiritigenin as a modulator of the Nrf2 signaling pathway: potential therapeutic implications
- Review, Var, NA
*antiOx↑, *AntiCan↑, *AntiTum↑, *AntiDiabetic↑, *cardioP↑, *RenoP↑, *NRF2↑, *NQO1↝, *HO-1↑, *SOD↑, *toxicity↓, *BioAv↓, *Half-Life↓, *BBB↑, *neuroP↑, *Stroke↓, *GSK‐3β↓, *p‑GSK‐3β↑, *hepatoP↑, *Inflam↓, *ROS↓, *MPO↓, *MDA↓,
7878- isoO,  Cisplatin,    Isoorientin Attenuates Cisplatin-Induced Nephrotoxicity Through the Inhibition of Oxidative Stress and Apoptosis via Activating the SIRT1/SIRT6/Nrf-2 Pathway
- in-vivo, Nor, NA
*antiOx↑, *RenoP↑, *chemoP↑, *SIRT1↑, *SIRT6↑, *NRF2↑, *HO-1↑, *NQO1↑, *NOX4↓, *ROS↓, *MPO↓, *MDA↓, *SOD↑, *GSH↑,
7890- IVT,    Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses
- in-vivo, Nor, NA
RenoP↑, *BUN↓, *creat↓, *TNF-α↓, *IL1β↓, *IL6↓, *MDA↓, *ROS↓, *NF-kB↓, *NRF2↑, *HO-1↑,
8104- KAE,    A comprehensive and mechanistic review on protective effects of kaempferol against natural and chemical toxins: Role of NF-κB inhibition and Nrf2 activation
- Review, Nor, NA
*ROS↓, *Inflam↓, *TNF-α↓, *IL6↓, *COX2/PTGS2↓, *NF-kB↓, *hepatoP↑, *RenoP↑, *cardioP↑, *neuroP↑,
8249- LCA,    Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells
- in-vitro, NSCLC, NA
tumCV↓, LDH↑, Apoptosis↑, selectivity↑, LC3II↑, TumAuto↑, ER Stress↑, CHOP/DDIT3↑, chemoP↑, RenoP↑, cl‑PARP↑, cl‑Casp7↑, cl‑Casp3↑,
8256- LCA,    Licochalcone A inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice
- in-vivo, Colon, CT26
TumVol?, TumCP↓, *RenoP↑, *creat↓, BUN↓, hepatoP↑, *ALAT↓, *AST↓, *NO↓, *lipid-P↓, *GSH↑, chemoP↑, Dose↝,
8225- LCA,  Cisplatin,    Licochalcone A protects against cisplatin-induced acute kidney injury via the modulation of Nrf2/Keap1-mediated ferroptosis and apoptosis
- in-vivo, Nor, NA
*RenoP↑, *Urea↓, *BUN↓, *creat↓, *Apoptosis↓, *Ferroptosis↓, *Iron↓, *ROS↓, *lipid-P↓, *mtDam↓, *NRF2↑,
8289- LE,  Cisplatin,    Effects of Glycyrrhizin in a Mouse Model of Lung Adenocarcinoma
- vitro+vivo, Lung, NA
TBXAS1/TxAS↓, PCNA↓, Weight?, RenoP↑, hepatoP↑,
8129- LF,    Study on the Therapeutic Benefit on Lactoferrin in Patients with Colorectal Cancer Receiving Chemotherapy
- Trial, CRC, NA
Dose↝, toxicity↓, INF-γ↝, other↑, *ROS↓, Imm↑, WBC↑, Neut↑, T-Cell↑, *antiOx↑, *GSH↑, *chemoP↑, *RenoP↑, *hepatoP↑, BUN↓, creat↓, ALAT↓, AST↓, RBC↑, PC↑, Mucositis↓, *AntiBio↑, *AntiViral↑, *AntiFungal↑, *Inflam↓,
8194- LGE,    Effect of lemongrass tea consumption on estimated glomerular filtration rate and creatinine clearance rate
- Trial, Nor, NA
*Dose↝, *GFR↓, *CCr / CrCl↓, *CCr / CrCl∅, *GFR∅, *RenoP↑,
8327- LIN,    Recent updates on bioactive properties of linalool
- Review, Var, NA
*AntiCan↑, *AntiBio↑, *neuroP↑, *Stress↓, *hepatoP↑, *RenoP↑, *ROS↓, ROS↑, *Inflam↓, *toxicity↓, TumCP↓, TumCCA↑, mtDam↑, MMP↓, compI↓, compII↓, ETC↓, ATP↓, angioG↓, ChemoSen↑, *GSH↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ALAT↓, *AST↓, chemoP↑,
8320- LIN,    Ameliorative Effect of Linalool in Cisplatin-Induced Nephrotoxicity: The Role of HMGB1/TLR4/NF-κB and Nrf2/HO1 Pathways
- in-vivo, Nor, NA
RenoP↑, Dose↝, *TLR4↓, *MyD88↓, *TRIF↓, *TNF-α↓, *IL1β↓, *IL6↓, *NF-kB↓, *chemoP↑, *Casp3↓, *Casp9↓, *BAX↓, *Bcl-2↑, ChemoSen↑, *cardioP?, *hepatoP↑, *Apoptosis↓, *antiOx↑, *Inflam↓, *ROS↓, *BUN?, *creat↓, *GSH↑, *SOD↑, *Catalase↑, *MDA↓, *NADPH↓, *NRF2↑, *HO-1↑,
8377- LT,    Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases
- Review, Asthma, NA
*PI3K↑, *Akt↑, *Inflam↓, *ROS↓, *BioAv↓, *RenoP↑, *cardioP↑, *neuroP↑, *antiAll↑, *AntiDiabetic↑, *hepatoP↑, *AntiThr↑, *toxicity↓, *IL10↓, *Sepsis↓, *TNF-α↓, *ROS↓, *GSH↑, *Catalase↑, *SOD↑, *MDA↓, *lipid-P↓, *IL4↓, *IL5↓, *PGE2↓, *PI3K↑, *Akt↑, *mTOR↑, *Beclin-1/ATG6↓, *Mucositis↓, *PLA2↓, STAT3↓, PD-L1↓, miR-34a↓, Casp3↑, Casp9↑, Bcl-2↓, BAX↑, Bax:Bcl2↑, Apoptosis↑, ROS↑, EMT↓, E-cadherin↓, DR5↑, LIMK1↓, Pain↓,
2930- LT,    Luteolin confers renoprotection against ischemia–reperfusion injury via involving Nrf2 pathway and regulating miR320
- in-vitro, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *NRF2↓,
3531- Lyco,    Lycopene attenuates the inflammation and apoptosis in aristolochic acid nephropathy by targeting the Nrf2 antioxidant system
- in-vivo, Nor, NA
*NRF2↑, *HO-1↑, *NQO1↑, *ROS↓, *mtDam↓, *Bcl-2↑, *BAX↓, *Casp9↓, *Casp3↓, *Apoptosis↓, *RenoP↑, *lipid-P↓, *SOD↑, *GPx↑, *Inflam↓, *TNF-α↓, *IL6↓, *IL10↓,
3264- Lyco,    Pharmacological potentials of lycopene against aging and aging‐related disorders: A review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *GSTs↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *iNOS↓, *NO↓, *TAC↑, *NOX4↓, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *IL1β↓, *TNF-α↓, *TLR2↓, *TLR4↓, *VCAM-1↓, *ICAM-1↓, *STAT3↓, *NF-kB↓, *ERK↓, *BP↓, ROS↓, PGE2↓, cardioP↑, *neuroP↑, *creat↓, *RenoP↑, *CRM↑,
3281- Lyco,  Chemo,    Lycopene Supplementation for Patients Under Cancer Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Review, Var, NA
eff↑, cardioP↑, eff?, PSA↓, RenoP↑,
1713- Lyco,    Lycopene: A Potent Antioxidant with Multiple Health Benefits
- Review, Nor, NA
*antiOx↑, *ROS⇅, *Dose↝, *eff↑, *LDL↓, *RenoP↑, *Inflam↓, neuroP↑, Rho↓,
8414- Lyco,    Exploring the Therapeutic Potential of Lycopene: Mechanisms, Biological Activities, and Health Benefits
- Review, Var, NA - Review, AD, NA
*ROS↓, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiArt↑, *Obesity↓, *Wound Healing↑, *BioAv↑, *GSTs↑, *Trx1↑, *SOD↑, *Catalase↑, *ALAT↓, *LDH↓, *AST↓, *MDA↓, *cognitive↑, *memory↑, *NeuroI↓, *Aβ↓, *LRP1↑, *RAGE↓, *NRF2↑, *HO-1↑, tumCV?, Bax:Bcl2↑, DNAdam↑, Apoptosis↑, β-catenin/ZEB1↓, cMyc↓, cycD1/CCND1↓, ROS↓, TumCCA↑, Akt↓, *Synergy↑, *MDA↓, *NF-kB↓, *TGF-β↓, *Casp3↓, *Catalase↑, *GSH↑, *Bcl-2↑, *IL10↑, *MUC1↑, *IBI↑, *RenoP↑, *ChemoSen↑, *Synergy↑, *Synergy↑, *BMD↑,
8464- Mg,  Cisplatin,    Efficacy of Prophylactic Magnesium Therapy for the Prevention of Cisplatin-Induced Renal Injury: A Meta-Analysis
- Review, Var, NA
RenoP↑, Dose↝, eff↝,
8687- MLT,    Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma
- in-vitro, CRC, T24/HTB-9 - in-vitro, Bladder, UMUC3
TumCP↓, TumCCA↑, Hif1a↓, NF-kB↓, Bcl-2↓, ROS↑, Akt↓, PCNA↓, cycD1/CCND1↓, BAX↓, Apoptosis?, ChemoSen↑, Wnt↓, β-catenin/ZEB1↓, COX2/PTGS2↓, PGE2↓, NF-kB↓, PI3K↓, Akt↓, P53↑, P21↑, *cardioP?, *NRF2↑, *HO-1↑, *RenoP↑, chemoP↑,
1777- MLT,    Melatonin as an antioxidant: under promises but over delivers
- Review, Var, NA
*ROS↓, *Fenton↓, *antiOx↑, *toxicity∅, *GPx↑, *GSR↑, *GSH↑, *NO↓, *Iron↓, *Copper↓, *IL1β↓, *iNOS↓, *Casp3↓, *BBB↑, *RenoP↑, chemoP↑, *Ca+2↝, eff↑, *PKCδ?, ChemoSen↑, eff↑, Akt↓, DR5↑, selectivity↑, ROS↑, Synergy↑,
3844- MO,    Review of the Safety and Efficacy of Moringa oleifera
- Review, Nor, NA
*antiOx↑, *RenoP↑, *hepatoP↑, *radioP↑, *eff↑, *toxicity↓, *ROS↓, *lipid-P↓, *DNAdam↓, *Catalase↑, *SOD↑, *GPx↑, *GSR↑, *GSTs↑, *AST↓, *ALAT↓, *ALP↓, *Bil↓,
3842- MO,    Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *hepatoP↑, *lipid-P↓, *ALAT↓, *AST↓, *ALP↓, *creat↓, *RenoP↑, NF-kB↓, ChemoSen↑, *memory?,
8896- MOR,    Morin hydrate ameliorates cisplatin-induced ER stress, inflammation and autophagy in HEK-293 cells and mice kidney via PARP-1 regulation
- vitro+vivo, Nor, HEK293
*PARP1↓, *Inflam↓, *RenoP↑,
8900- MOR,  Cisplatin,    Morin Hydrate Mitigates Cisplatin-Induced Renal and Hepatic Injury by Impeding Oxidative/Nitrosative Stress and Inflammation in Mice
- in-vivo, Nor, NA
Dose↝, RenoP↑, *ROS↓, *TAC↑, *Inflam↓,
8883- MOR,  5-FU,    Morin Mitigates 5-Fluorouracil-Induced Nephrotoxicity by Activating Nrf2/HO-1 and FXR, and Suppressing ERK/VCAM-1 and NF-κB Pathways
- in-vivo, Nor, NA
*Inflam↓, *antiOx↑, *Dose↝, *Urea↓, *creat↓, *ROS↓, *NRF2↑, *HO-1↑, *NR1H4↑, *RenoP↑, *TNF-α↓, *IL6↓, *ERK↓, *VCAM-1↓, *NF-kB↓, *chemoP↑,
5619- NaHCO3,    Safety and efficacy of sodium bicarbonate for treating metabolic acidosis in chronic kidney disease: A systematic review and meta-analysis
- Review, CKD, NA
*RenoP↑, toxicity↓, GFR↑, toxicity↝,
8453- OM,    Origanum majorana Attenuates Nephrotoxicity of Cisplatin Anticancer Drug through Ameliorating Oxidative Stress
- in-vivo, Nor, NA
Dose↝, creat↓, Urea↓, uricA↓, BUN↓, MDA↓, GSH↑, SOD↑, Catalase↑, RenoP↑, *ROS↓,

Showing Research Papers: 51 to 100 of 134
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 134

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↓, 2,   Catalase↑, 2,   GSH↓, 4,   GSH↑, 1,   GSR↑, 1,   GSTs↑, 1,   H2O2↑, 1,   HO-1↓, 1,   HO-1↑, 1,   lipid-P↓, 1,   lipid-P↑, 4,   MDA↓, 1,   MDA↑, 1,   NQO1↑, 1,   NRF2↓, 2,   NRF2↑, 2,   ROS↓, 5,   ROS↑, 23,   i-ROS↑, 1,   mt-ROS↑, 1,   SOD↓, 2,   SOD↑, 2,   TAC↓, 1,   uricA↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,   IronCh∅, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 2,   CDC25↓, 4,   compI↓, 1,   compII↓, 1,   ETC↓, 1,   mitResp↓, 1,   mtDam↑, 1,   mt-OXPHOS↓, 1,   PGC-1α↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 3,   AMPK↑, 3,   ATP↓, 2,   BHB↑, 1,   GlucoseCon↓, 2,   Glycolysis↓, 4,   GSK‐3β↑, 3,   p‑GSK‐3β↓, 1,   HK2↓, 3,   HMGCS2↑, 1,   lactateProd↓, 1,   LDHA↓, 1,   LDL↓, 1,   NADPH↑, 1,   PCK1↓, 1,   PDK1 / PDPK1↓, 2,   PKM2↓, 1,   SCD1↓, 1,   SIRT1↑, 1,   TCA↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 2,   APAF1↑, 1,   Apoptosis?, 2,   Apoptosis↑, 21,   BAD↑, 1,   Bak↓, 1,   Bak↑, 2,   BAX↓, 1,   BAX↑, 15,   Bax:Bcl2↓, 1,   Bax:Bcl2↑, 3,   Bcl-2↓, 15,   Bcl-xL↓, 4,   BID↑, 1,   BNIP3↑, 2,   Casp↑, 1,   Casp3↓, 1,   Casp3↑, 10,   cl‑Casp3↑, 3,   cl‑Casp7↑, 1,   Casp8↑, 7,   Casp9↑, 7,   cl‑Casp9↑, 4,   cFLIP↓, 1,   Cyt‑c↑, 12,   Diablo↑, 1,   DR5↑, 4,   FADD↑, 1,   Fas↑, 4,   FasL↑, 1,   HEY1↓, 1,   IAP1↓, 1,   IAP2/BIRC3↓, 2,   iNOS↓, 2,   Mcl-1↓, 2,   MDM2↓, 1,   p38↑, 1,   p‑p38↓, 1,   PUMA↑, 1,   survivin↓, 3,   TumCD↑, 2,   XIAP↓, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 18,   Akt↑, 1,   p‑Akt↓, 3,   cMET↓, 1,   p‑cMET↑, 1,   EGFR↓, 3,   EGFR↑, 1,   ERK↓, 7,   p‑ERK↓, 1,   HER2/EBBR2↓, 2,   JAK1↓, 1,   JNK↑, 1,   LIMK1↓, 1,   MAPK↓, 5,   MAPK↑, 2,   mTOR↓, 6,   mTOR↑, 1,   mTORC2↓, 2,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 10,   p‑PI3K↓, 2,   PKCδ↓, 1,   PTEN↑, 1,   RAS↓, 2,   RAS↑, 1,   SHP1↑, 1,   STAT↓, 1,   STAT3↓, 6,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↑, 2,   cMyc↓, 5,   DNMT1↓, 3,   DNMT3A↓, 1,   EZH2↓, 1,   FOXO3↑, 1,   H3↑, 1,   p‑H3↓, 1,   HDAC↓, 5,   HDAC1↓, 1,   HDAC4↓, 1,   miR-124-3p↓, 1,   miR-34a↓, 1,   miR-34a↑, 1,   MYCN↓, 1,   OCT4↓, 1,   other↓, 1,   other↑, 1,   SOX2↓, 1,   tumCV?, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 4,   eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 5,   GRP78/BiP↑, 2,   HSP90↓, 1,   PERK↑, 1,   p‑PERK↑, 1,   UPR↑, 2,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   Beclin-1/ATG6↑, 2,   LC3II↑, 3,   LC3s↑, 1,   TumAuto↑, 5,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 2,   BRCA1↑, 1,   DNAdam↑, 7,   hTERT/TERT↓, 2,   P53↑, 10,   PARP↑, 4,   cl‑PARP↑, 4,   PARP1↑, 1,   PCNA↓, 4,   TOP1↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 3,   CDK1↑, 1,   CDK2↓, 3,   CDK4↓, 6,   CDK6↑, 1,   CHK1↓, 1,   CHK1↑, 1,   Chk2↓, 1,   Chk2↑, 1,   cycA1/CCNA1↓, 2,   CycB/CCNB1↓, 4,   cycD1/CCND1↓, 7,   cycE/CCNE↓, 1,   cycE/CCNE↑, 1,   GADD45A↑, 2,   Ki-67↓, 4,   P21↓, 1,   P21↑, 8,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 3,   p‑pRB↓, 1,   RB1↑, 1,   p‑RB1↓, 1,   TumCCA↑, 20,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP7/OP1↓, 1,   BMPs↑, 1,   CD133↓, 1,   CSCs?, 1,   CSCs↓, 2,   Diff↑, 2,   FGF↓, 1,   HH↓, 1,   Ki-67↓, 4,   Let-7↑, 1,   mTORC1↓, 2,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   NOTCH1↑, 3,   Shh↓, 1,   TumCG↓, 4,   TumCP↓, 18,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AP-1↓, 2,   Ca+2↑, 6,   E-cadherin↓, 1,   E-cadherin↑, 3,   EMT↓, 8,   EMT↑, 1,   FAK↓, 2,   Fibronectin↓, 1,   LRP1↓, 1,   MALAT1↓, 1,   MMP-10↓, 1,   MMP1↓, 1,   MMP13↓, 2,   MMP2↓, 7,   MMP3↓, 1,   MMP7↓, 1,   MMP9↓, 8,   MMP9↑, 1,   MMPs↓, 5,   MTA1↓, 1,   MUC4↓, 1,   N-cadherin↓, 2,   PDGF↓, 1,   Rho↓, 3,   ROCK1↓, 1,   Slug↓, 2,   Smad1↑, 1,   Snail↓, 2,   TET1↑, 3,   TGF-β↓, 1,   TIMP2↓, 1,   TIMP2↑, 1,   TumCI↓, 7,   TumCMig↓, 7,   TumMeta↓, 5,   Twist↓, 5,   uPA↓, 4,   Vim↓, 2,   Zeb1↓, 1,   β-catenin/ZEB1↓, 5,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 12,   HIF-1↑, 1,   Hif1a↓, 8,   TBXAS1/TxAS↓, 1,   VEGF↓, 12,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

CLDN1↓, 1,   GLUT1↓, 1,   MMP↓, 11,   MMP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↓, 1,   CD44↓, 1,   CD47↓, 1,   CD8+↑, 2,   COX2/PTGS2↓, 9,   COX2/PTGS2↑, 1,   CXCR4↓, 1,   DR4↑, 1,   HMGB1↓, 1,   ICAM-1↓, 1,   IL1↓, 1,   IL10↓, 1,   IL1β↓, 4,   IL1β↑, 1,   IL6↓, 5,   IL8↓, 1,   Imm↑, 2,   INF-γ↝, 1,   Inflam↓, 4,   MCP1/CCL2↓, 2,   Neut↑, 1,   NF-kB↓, 21,   NF-kB↑, 1,   NK cell↑, 1,   NLRP3↓, 1,   PD-1↓, 1,   PD-L1↓, 3,   PGE2↓, 5,   PSA↓, 1,   T-Cell↑, 1,   TLR4↓, 3,   TNF-α↓, 6,   TNF-α↑, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER-α36↓, 1,   PPARα↓, 1,   PPARγ↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 4,   BioAv↑, 4,   BioAv↝, 1,   CBR1↓, 1,   ChemoSen↓, 1,   ChemoSen↑, 17,   ChemoSen∅, 1,   CompStab↑, 1,   Dose↑, 1,   Dose↝, 13,   eff?, 1,   eff↑, 9,   eff↝, 2,   Half-Life↓, 2,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 2,   RadioS↑, 4,   selectivity↑, 7,   Synergy↑, 18,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   ALP↓, 1,   AST↓, 2,   BRCA1↑, 1,   BUN↓, 3,   CEA↓, 1,   creat↓, 4,   E6↓, 1,   E7↓, 1,   EGFR↓, 3,   EGFR↑, 1,   EZH2↓, 1,   HER2/EBBR2↓, 2,   hTERT/TERT↓, 2,   IL6↓, 5,   LDH↓, 2,   LDH↑, 1,   Maspin↑, 1,   PC↑, 1,   PD-L1↓, 3,   PSA↓, 1,   RBC↑, 1,   Urea↓, 1,   WBC↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 7,   AntiTum↑, 6,   cardioP↑, 4,   CardioT↓, 1,   chemoP↑, 16,   chemoPv↑, 3,   GFR↑, 1,   hepatoP↑, 9,   hepatoP∅, 1,   Mucositis↓, 2,   neuroP↑, 7,   NP/CIPN↓, 1,   NP/CIPN↑, 1,   Pain↓, 1,   PFS↑, 1,   QoL↑, 3,   radioP↑, 3,   RenoP↓, 1,   RenoP↑, 33,   RenoP∅, 1,   Risk↓, 1,   toxicity↓, 3,   toxicity↝, 2,   TumVol?, 1,   TumVol↓, 1,   TumW↓, 1,   Weight?, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 1,  
Total Targets: 380

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 50,   ARE↑, 1,   Bil↓, 1,   Bil↑, 1,   Catalase↑, 30,   Copper↓, 1,   Fenton↓, 3,   GCLC↑, 1,   GCLM↑, 1,   GPx↓, 1,   GPx↑, 16,   GPx4↑, 3,   GSH↑, 39,   GSR↓, 1,   GSR↑, 5,   GSTs↓, 1,   GSTs↑, 8,   H2O2↓, 2,   HDL↑, 3,   HO-1↓, 1,   HO-1↑, 27,   HO-1⇅, 1,   Iron↓, 2,   Iron∅, 1,   Keap1↓, 3,   Keap1↑, 1,   lipid-P↓, 28,   MDA↓, 35,   MPO↓, 5,   NADH↓, 1,   NOX4↓, 2,   NQO1↑, 4,   NQO1↝, 1,   NRF2↓, 2,   NRF2↑, 37,   Prx↑, 1,   RNS↓, 1,   ROS↓, 80,   ROS⇅, 1,   ROS∅, 1,   SOD?, 1,   SOD↑, 39,   SOD1↑, 1,   SOD2↑, 1,   TAC↑, 6,   TBARS↓, 1,   Trx1↑, 1,   UCPs↑, 1,   uricA↓, 5,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 4,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compII↑, 1,   compIII↑, 1,   DRP1/DNM1L↓, 1,   MFN2↑, 2,   mtDam↓, 2,   PGC-1α↑, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   15-LOX/ALOX15↓, 1,   ALAT↓, 19,   ALAT∅, 1,   AMPK↑, 4,   p‑AMPK↑, 1,   ATP↑, 5,   Buty↑, 1,   cAMP↑, 1,   CRM↑, 1,   glucose↓, 1,   glucose↝, 1,   GlucoseCon↑, 1,   GSK‐3β↓, 2,   GSK‐3β↑, 2,   p‑GSK‐3β↑, 1,   HMG-CoA↓, 1,   KeyT↝, 1,   LDL↓, 6,   lipidLev↓, 2,   NADPH↓, 4,   PLA2↓, 1,   SCFAs↑, 1,   SIRT1↓, 1,   SIRT1↑, 7,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 16,   ASC↓, 2,   BAX↓, 8,   Bax:Bcl2↓, 1,   Bcl-2↑, 7,   Casp1↓, 2,   Casp12↓, 3,   Casp3?, 1,   Casp3↓, 15,   Casp3∅, 1,   cl‑Casp3↓, 1,   cl‑Casp8↑, 1,   Casp9↓, 5,   Casp9∅, 1,   Cyt‑c↓, 3,   Cyt‑c∅, 1,   Fas↓, 2,   Ferroptosis↓, 7,   GranB/GZMB↓, 1,   iNOS↓, 13,   iNOS↑, 2,   p38↓, 4,   Pyro↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 3,   Akt↑, 5,   p‑Akt↑, 2,   ERK↓, 4,   ERK↑, 1,   p‑ERK↑, 1,   HGF/c-Met↑, 1,   IKKα↑, 1,   JAK2↓, 1,   JNK↓, 4,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 8,   MAPK↑, 1,   p‑MAPK↓, 1,   mTOR↓, 3,   mTOR↑, 1,   PI3K↓, 4,   PI3K↑, 4,   PKCδ?, 1,   STAT3↓, 2,   STAT5↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   ATF2↑, 1,   ATF4↓, 1,   cMyc↓, 1,   DNMT1↓, 2,   DNMTs↓, 1,   FOXO3↑, 1,   KLF4↑, 1,   other↓, 1,   other↑, 4,   other↝, 2,   other∅, 1,   Prot↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 3,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   ER Stress↓, 4,   GRP78/BiP↓, 3,   GRP78/BiP↑, 1,   GRP94↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   MitoP↓, 1,   p62↓, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 5,   DNArepair↑, 1,   p16↓, 1,   P53↓, 2,   PARP∅, 1,   PARP1↓, 1,   PCNA↓, 1,   SIRT6↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

HH↓, 1,   IGF-1↑, 1,   IGFBP1↑, 1,   neuroG↑, 1,   TumCP↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 4,   AP-1↓, 2,   mt-ATPase↑, 1,   BACH1↓, 1,   Ca+2↓, 1,   Ca+2↝, 2,   Cartilage↑, 2,   COL1↓, 1,   Fibrosis↓, 1,   LRP1↑, 1,   MMP13↓, 2,   MMP9↓, 1,   MUC1↑, 1,   PAI-1/SERPINE1↓, 1,   p‑Rac1↓, 1,   TGF-β↓, 2,   TGF-β↑, 1,   TGF-β1↓, 1,   TumCI↓, 1,   TXNIP↓, 1,   α-SMA↓, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

eNOS↑, 1,   Hif1a↓, 1,   NO↓, 9,   VCAM-1↓, 4,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 5,   BBB↝, 1,   GastroP↑, 4,   GLUT2↑, 1,   GLUT4↑, 1,   H+/K+-ATPase↓, 1,   IBI↑, 4,   MMP↑, 6,   NHE3↑, 1,   TJ↑, 1,   TRPV1↑, 2,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 2,   CD8+↑, 1,   COX1↓, 2,   COX2/PTGS2↓, 21,   HMGB1↓, 1,   ICAM-1↓, 3,   IFN-γ↓, 3,   IL1↓, 2,   IL10↓, 6,   IL10↑, 3,   IL12↓, 1,   IL17↓, 1,   IL18↓, 2,   IL1β↓, 23,   IL2↓, 2,   IL4↓, 3,   IL5↓, 1,   IL6↓, 26,   IL6↑, 2,   IL8↓, 6,   Imm↑, 5,   Inflam↓, 56,   Inflam↑, 1,   IRF3↓, 2,   LPS↓, 1,   MCP1/CCL2↓, 2,   MCT1↓, 1,   MyD88↓, 4,   NeuroI↓, 1,   NF-kB↓, 27,   NLRP3↓, 7,   PGE2↓, 5,   RAGE↓, 2,   RANTES↓, 1,   TLR2↓, 3,   TLR4↓, 9,   TNF-α↓, 38,   TRIF↓, 2,   VitD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 7,   BChE↓, 3,   BDNF↑, 3,   ChAT↑, 1,   GABA↑, 1,   NGF↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 2,   APP↓, 1,   Aβ↓, 10,   BACE/β-secretase↓, 4,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 2,   ACE2↓, 1,   GLP-1R↑, 1,   NR1H4↑, 1,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 16,   BioAv↑, 18,   BioAv↝, 5,   ChemoSen↑, 2,   Dose↝, 14,   eff↓, 1,   eff↑, 11,   GSTA1↑, 1,   Half-Life↓, 3,   Half-Life↑, 2,   Half-Life↝, 5,   MRP↓, 1,   P-gp/ABCB1↓, 2,   selectivity↑, 1,   Synergy↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 19,   ALAT∅, 1,   ALB↑, 1,   ALB↝, 1,   ALP↓, 5,   AST↓, 19,   AST∅, 1,   BG↓, 2,   Bil↓, 1,   Bil↑, 1,   BloodF↑, 2,   BMD↑, 2,   BP↓, 4,   BUN?, 1,   BUN↓, 10,   CCr / CrCl↓, 1,   CCr / CrCl∅, 1,   creat↓, 20,   CRP↓, 1,   IL6↓, 26,   IL6↑, 2,   IRes↝, 1,   KeyT↝, 1,   LDH↓, 4,   NOS2↓, 1,   RAGE↓, 2,   Urea↓, 5,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 2,   antiAll↑, 2,   AntiArt↑, 3,   AntiCan↑, 8,   antiD↓, 1,   AntiDiabetic↑, 11,   antiM↑, 1,   antiPs↑, 2,   antiPy↑, 1,   AntiTum↑, 3,   cardioP?, 2,   cardioP↑, 30,   cardioP⇅, 1,   chemoP↑, 11,   chemoPv↑, 1,   cognitive↑, 9,   diuretic↑, 3,   GFR↓, 1,   GFR↑, 1,   GFR∅, 1,   hepatoP↑, 48,   memory?, 1,   memory↑, 7,   motorD↑, 1,   Mucositis↓, 1,   neuroP?, 1,   neuroP↑, 33,   Obesity↓, 8,   OS↑, 2,   Pain↓, 2,   QoL↑, 2,   radioP↑, 5,   RenoP↓, 2,   RenoP↑, 96,   RenoP↝, 2,   Strength↑, 1,   Stress↓, 1,   Stroke↓, 6,   toxicity↓, 14,   toxicity↝, 2,   toxicity∅, 2,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 4,   AntiFungal↑, 4,   AntiP↑, 1,   AntiViral↑, 4,   Bacteria↓, 11,   GutMicro↑, 7,   Sepsis↓, 5,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 2,  
Total Targets: 361

Scientific Paper Hit Count for: RenoP, K,Renoprotection/Nephroprotective
14 Thymoquinone
12 Cisplatin
5 Baicalein
5 Hydrogen Gas
5 Lycopene
4 Berberine
4 Chrysin
3 Silver-NanoParticles
3 Ashwagandha(Withaferin A)
3 Melatonin
3 Boron
3 Capsaicin
3 Licochalcone A
3 Morin
3 Selenium NanoParticles
3 Shikonin
2 Allicin (mainly Garlic)
2 Alpha-Lipoic-Acid
2 Curcumin
2 EGCG (Epigallocatechin Gallate)
2 Betulinic acid
2 Carvacrol
2 Chlorogenic acid
2 Dandelion Root
2 Ferulic acid
2 Fisetin
2 Grapeseed extract
2 Hibiscus sabdariffa
2 Hyperoside
2 Isoliquiritigenin
2 Isovitexin
2 Linalool
2 Luteolin
2 Chemotherapy
2 Moringa oleifera
2 5-fluorouracil
2 Marjoram (Origanum majorana)
2 Resveratrol
2 Rutin
2 Silymarin (Milk Thistle) silibinin
1 Annona atemoya Seed Extract
1 Astragalus
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Apigenin (mainly Parsley)
1 doxorubicin
1 Ascorbyl Palmitate
1 Huperzine A/Huperzia serrata
1 α-Bisabolol / Chamomile oil
1 Black Seed Oil/Nigella sativa
1 Lecithin
1 Coenzyme Q10
1 Selenium
1 Crocetin
1 Cucurbitacin
1 D-limonene
1 Echinacea
1 Emodin
1 Fucoidan
1 Ginkgo biloba
1 Germanium inorganic
1 Honokiol
1 phytic acid, Inositol hexakisphosphate
1 isoorientin
1 Kaempferol
1 Licorice
1 Lactoferrin/Talactoferrin
1 Lemongrass Extract/Citral
1 Magnesium
1 Bicarbonate(Sodium)
1 Propolis -bee glue
1 Quercetin
1 Rosmarinic acid
1 buckwheat sprouts
1 Gold NanoParticles
1 Date Fruit Extract
1 Sulforaphane (mainly Broccoli)
1 Selenite (Sodium)
1 Matrine
1 Radiotherapy/Radiation
1 methotrexate
1 Thymol-Thymus vulgaris
1 Urolithin
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1175  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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