cardioP Cancer Research Results

cardioP, cardioProtective: Click to Expand ⟱
Source:
Type:
CardioProtective


Scientific Papers found: Click to Expand⟱
5825- CAP,    Bioavailability of capsaicin and its implications for drug delivery
- Review, Var, NA - Review, Arthritis, NA - Review, Obesity, NA
*AntiCan↑, *TRPV1↑, *cardioP↑, AntiCan↓, Apoptosis↑, ChemoSen↑, *Inflam↓, *Pain↓, *AntiAg↑, *Weight↓, *BioAv↑, BioAv↑, Half-Life↝, Half-Life↓,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
5885- CAR,    Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
TRPM7↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, toxicity↓, *Inflam↓, AntiDiabetic↑, cardioP↑, neuroP↑, selectivity↑, Apoptosis↑, p‑Cofilin↑, F-actin↓, PI3K↓, Akt↓, MEK↓, MAPK↓,
5881- CAR,    Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *toxicity↓, *Pain↓, *other↑, *cardioP↑, *RenoP↑, *neuroP↑, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *Obesity↓, *AntiAg↑, *BioAv↓, BioAv↝, *OS↑, MMP↓, ROS↑, *MDA↓, *lipid-P↓, *COX2↓, *Dose↝,
5888- CAR,    Therapeutic application of carvacrol: A comprehensive review
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Park, NA
*antiOx↑, *AntiCan↑, *AntiDiabetic↑, *cardioP↑, *Obesity↓, *hepatoP↑, *AntiAg↑, *Bacteria↓, *Imm↑, MMP2↓, MMP9↓, Apoptosis↓, MMP↓, ERK↓, PI3K↓, ALAT↓, *ROS↓, *Catalase↑, *SOD↑, *GPx↑, *AST↓, *LDH↓, *necrosis↓, ROS↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, NOTCH↓, IL6↓, chemoP↑, *Pain↓, *neuroP↑, *TRPM7↓, *motorD↑, *NF-kB↓, *COX2↓, *MDA↓,
5900- CAR,  TV,    Lights and Shadows of Essential Oil-Derived Compounds: Antimicrobial and Anti-Inflammatory Properties of Eugenol, Thymol, Cinnamaldehyde, and Carvacrol
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *cardioP↑, *neuroP↑, *NADPH↓, *NRF2↑, *HO-1↑, *IL1β↓, *TNF-α↓,
5893- CAR,  TV,    Thymol and Carvacrol: Molecular Mechanisms, Therapeutic Potential, and Synergy With Conventional Therapies in Cancer Management
- Review, Var, NA
*Inflam↓, AntiCan↑, PI3K↓, Akt↓, mTOR↓, NOTCH↓, PIK3CA↓, EGFR↓, Hif1a↓, VEGF↓, ChemoSen↑, RadioS↑, eff↝, *cardioP↑, *neuroP↑, *hepatoP↑, Apoptosis↑, MMP↓, Casp3↑, ROS↑, DNAdam↑, eff↑, BAX↑, BAD↑, FasL↑, Cyt‑c↑, Casp9↑, Casp8↑, TumCCA↑, P21↑, Smo↓, Gli1↓, JNK↑, ERK↓, MAPK↓, TRPM7↓, Wnt/(β-catenin)↓, BioAv↝, BioAv↑,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, asthmatic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *eff↑, *BChE↓, *CRP↓,
5925- CAR,    Neuroprotective effects of carvacrol against Alzheimer’s disease and other neurodegenerative diseases: A review
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AChE↓, *BBB↑, *cardioP↑, *neuroP↑, *memory↑, *TAC↑, *ROS↓, *lipid-P↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *cognitive↑, *IL1β↓, *COX2↓, *TNF-α↓, *TLR4↓, *BDNF↑, *PKCδ↑, *5LO↓, *TRPM7↓, *GSH↑, *other↑, *Ferroptosis↓, *GPx4↑,
6018- CGA,    Chlorogenic acid: a review on its mechanisms of anti-inflammation, disease treatment, and related delivery systems
- Review, Var, NA - Review, RCC, NA
*BioAv↓, *Inflam↓, *TNF-α↓, *NO↓, *COX2↓, *PGE2↓, *NF-kB↓, *IL6↓, *IL1β↓, *TLR2↓, *MAPK↓, *NRF2↓, *HO-1↑, *NQO1↑, *cardioP↑, *neuroP↑, *SOD↑, *GSH↑, *ROS↓, *LDH↓, *MDA↓, *cognitive↑, *eff↑,
6017- CGA,    Therapeutic Potential of Chlorogenic Acid in Chemoresistance and Chemoprotection in Cancer Treatment
- Review, Var, NA
AntiCan↑, *chemoP↑, TNF-α↓, COX2↓, IL6↓, eff↑, PD-L1↓, *cognitive↓, *Aβ↓, *TAC↑, *SOD↑, *eff↑, *eff↑, ChemoSen↑, tumCV↓, Apoptosis↑, ERK↓, chemoP↑, *GPx↑, *GSTs↑, *GSH↑, *SOD↑, *Catalase↑, *ROS↓, *lipid-P↓, *MDA↓, *Casp3↓, *HO-1↓, cardioP↑, radioP↑,
6016- CGA,    Coffee Chlorogenic Acids Incorporation for Bioactivity Enhancement of Foods: A Review
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
antiOx↑, *Bacteria↓, AntiCan↑, *Inflam↓, *cardioP↑, *AntiDiabetic↑, *GutMicro↑, *eff↑, *eff↑, *ROS↓, *IronCh↑, *neuroP↑, *AChE↓, *BChE↓, *chemoPv↑, *BioAv⇅,
6002- CGA,    Chlorogenic Acid: A Systematic Review on the Biological Functions, Mechanistic Actions, and Therapeutic Potentials
- Review, Var, NA - Review, Diabetic, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *Inflam↓, *antiOx↑, *cardioP↑, *NRF2↑, *AMPK↑, *SOD↑, *Catalase↑, *GSH↑, *GPx↑, *ROS↓, *TNF-α↓, *IL6↓, *NF-kB↓, *COX2↓, *glucose↓, *TRPC1↓, *Ca+2↓, *HO-1↑, *NF-kB↓, *PPARα↝, *Hif1a↓, *JNK↓, *BP↓, *AntiDiabetic↑, *hepatoP↑, *TLR4↓, *NRF2↑, *Casp↓, *neuroP↑, *Aβ↓, *LDH↓, *MDA↓, *memory↑, *AChE↓, *eff↑, EMT↝, N-cadherin↓, E-cadherin↑, TumCCA↑, ROS↑, p‑P53↑, HO-1↑, NRF2↑, ChemoSen↑, mtDam↑, Casp3↑, Casp9↑, PARP↑, Bax:Bcl2↑, TumCG↓, cycD1/CCND1↓, cMyc↓, CDK2↓, mitResp↓, Glycolysis↓, Hif1a↓, PCNA↓, p‑GSK‐3β↓, VEGF↓, PI3K↓, Akt↓, mTOR↓, OS↑,
6013- CGA,    Advances in Pharmacological Properties, Molecular Mechanisms, and Bioavailability Strategies of Chlorogenic Acid in Cardiovascular Diseases Therapy
- Review, CardioV, NA
*BioAv↝, *BioAv↝, *BP↓, *ROS↓, *NADPH↓, *AntiAg↑, *TXA2↓, *antiOx↑, *cardioP↑, *Inflam↓, *SOD↑, *Catalase↑, *Ferroptosis↓, *NF-kB↓, *JNK↓, *NRF2↑, *HO-1↑, *toxicity↓, *BioAv↓, *BioAv↑, *BioAv↑, eff↑,
6008- CGA,    Risk Assessment of Chlorogenic and Isochlorogenic Acids in Coffee By-Products
- Review, Nor, NA
*toxicity↓, *antiOx↑, *Bacteria↓, *AntiDiabetic↑, *neuroP↑, *Inflam↓, *cardioP↑, *BP↓, *other↓, eff↓,
6011- CGA,    Chlorogenic Acid’s Role in Metabolic Health: Mechanisms and Therapeutic Potential
- Review, Nor, NA
*BioAv↓, *antiOx↑, *Inflam↓, *Bacteria↓, *hepatoP↑, *cardioP↑, *neuroP↑, *ROS↓, *NF-kB↓, *NRF2↑, *Obesity↓, *GutMicro↑, *AntiAg↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *OCLN↓, *VEGF↓, BioAv↝,
6023- CGA,    Pharmacological advances of the chlorogenic acids family: current insights and future research directions
- Review, AD, NA - Review, Park, NA - Review, IBD, NA
*Aβ↓, *neuroP↑, *cardioP↑, *GastroP↑, *RenoP↑, *hepatoP↑, *Obesity↓, *Bacteria↓, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *GutMicro↑, *IBI↑, *MCT1↓, *NF-kB↓, *DNMT1↓,
6087- CHOC,    Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial
- Trial, Nor, NA
*cardioP↑, *Dose↝, *BP↓, *Inflam↓, *AntiAg↑, *Risk↓,
6090- CHOC,    Cocoa Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Review, Nor, NA
*Dose↝, *cardioP↑,
6091- CHOC,    Chocolate Consumption in Relation to All-Cause and Cause-Specific Mortality in Women: The Women's Health Initiative
- Study, Nor, NA
*Risk↓, *cardioP↑, *OS↑,
6084- CHOC,    Cocoa Polyphenols and Their Potential Benefits for Human Health
- Review, Nor, NA - Review, Stroke, NA - Review, IBD, NA
*lipid-P↓, *ROS↓, *Inflam↓, *BP↓, *cardioP↑, *chemoPv↑, *BioAv⇅, *antiOx↑, *Risk↓, *5LO↓, *AntiAg↑, *Imm↑, *NF-kB↓, *other↓, CYP1A1↓, COX2↓, *Obesity↓, *cognitive↑,
6098- Chol,    Choline
- Review, Nor, NA - Review, AD, NA
*BioAv↝, *Dose↝, *cardioP↑, *BP↓, *cognitive↑, *memory↑, eff∅,
6107- Chol,    Choline supplements: An update
- Review, AD, NA
*memory↑, *cognitive↑, *Dose↝, *BBB↑, *cardioP↑, *ROS↓, *TMAO↑, *memory∅, *eff↑,
3700- Chol,    Eggs and Health Special Issue
- Review, Nor, NA
*other↑, *other↑, *Inflam↓, *ROS↓, *antiOx↑, *Iron↑, *cardioP∅,
2807- CHr,    Evidence-based mechanistic role of chrysin towards protection of cardiac hypertrophy and fibrosis in rats
- in-vivo, Nor, NA
*antiOx↑, Inflam↓, *cardioP↑, *GSH↑, *SOD↑, *Catalase↑, *GAPDH↑, *BAX↓, *Bcl-2↑, *PARP↓, *Cyt‑c↓, *Casp3↓, *NOX4↓, *NRF2↑, *HO-1↑, *HSP70/HSPA5↑,
2782- CHr,    Broad-Spectrum Preclinical Antitumor Activity of Chrysin: Current Trends and Future Perspectives
- Review, Var, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *Inflam↓, *hepatoP↑, *neuroP↑, *BioAv↓, *cardioP↑, *lipidLev↓, *RenoP↑, *TNF-α↓, *IL2↓, *PI3K↓, *Akt↓, *ROS↓, *cognitive↑, eff↑, cycD1/CCND1↓, hTERT/TERT↓, VEGF↓, p‑STAT3↓, TumMeta↓, TumCP↓, eff↑, eff↑, IL1β↓, IL6↓, NF-kB↓, ROS↑, MMP↓, Cyt‑c↑, Apoptosis↑, ER Stress↑, Ca+2↑, TET1↑, Let-7↑, Twist↓, EMT↓, TumCCA↑, Casp3↑, Casp9↑, BAX↑, HK2↓, GlucoseCon↓, lactateProd↓, Glycolysis↓, SHP1↑, N-cadherin↓, E-cadherin↑, UPR↑, PERK↑, ATF4↑, eIF2α↑, RadioS↑, NOTCH1↑, NRF2↓, BioAv↑, eff↑,
2785- CHr,    Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin
- Review, Var, NA
*NF-kB↓, *COX2↓, *iNOS↓, angioG↓, TOP1↓, HDAC↓, TNF-α↓, IL1β↓, cardioP↑, RenoP↑, neuroP↑, LDL↓, BioAv↑, eff↑, cycD1/CCND1↓, hTERT/TERT↓, MMP-10↓, Akt↓, STAT3↓, VEGF↓, EGFR↓, Snail↓, Slug↓, Vim↓, E-cadherin↑, eff↑, TET1↑, ROS↑, mTOR↓, PPARα↓, ER Stress↑, Ca+2↑, ERK↓, MMP↑, Cyt‑c↑, Casp3↑, HK2↓, NRF2↓, HO-1↓, MMP2↓, MMP9↓, Fibronectin↓, GRP78/BiP↑, XBP-1↓, p‑eIF2α↑, *AST↓, ALAT↓, ALP↓, LDH↓, COX2↑, Bcl-xL↓, IL6↓, PGE2↓, iNOS↓, DNAdam↑, UPR↑, Hif1a↓, EMT↓, Twist↓, lipid-P↑, CLDN1↓, PDK1↓, IL10↓, TLR4↓, NOTCH1↑, PARP↑, Mcl-1↓, XIAP↓,
2788- CHr,    Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action
- Review, Var, NA
*neuroP↑, *Inflam↓, *ROS↓, NF-kB↓, *PCNA↓, *COX2↓, ChemoSen↑, Hif1a↓, angioG↓, *chemoPv↑, PDGF↓, *memory↑, *RenoP↑, *PPARα↑, *lipidLev↓, *hepatoP↑, *cardioP⇅, *BioAv↓,
2790- CHr,    Chrysin: Pharmacological and therapeutic properties
- Review, Var, NA
*hepatoP↑, *neuroP↓, *ROS↓, *cardioP↑, *Inflam↓, eff↑, hTERT/TERT↓, cycD1/CCND1↓, MMP9↓, MMP2↓, TIMP1↑, TIMP2↑, BioAv↑, HK2↓, ROS↑, MMP↓, Casp3↑, ADP:ATP↑, Apoptosis↑, ER Stress↑, UPR↑, GRP78/BiP↝, eff↑, Ca+2↑,
3888- Cin,    Cinnamon, a promising prospect towards Alzheimer's disease
- NA, AD, NA
*tau↓, *Aβ↓, *neuroP↑, *ROS↓, *Inflam↓, *cardioP↑, *antiOx↑, *cognitive↑, *BBB↑, *p‑GSK‐3β↑, *AChE↓,
3892- Cin,    Cinnamon from the selection of traditional applications to its novel effects on the inhibition of angiogenesis in cancer cells and prevention of Alzheimer's disease, and a series of functions such as antioxidant, anticholesterol, antidiabetes, antibacterial, antifungal, nematicidal, acaracidal, and repellent activities
- Review, AD, NA - Review, Var, NA
*antiOx↑, *Inflam↓, *cardioP↑, angioG↓, VEGF↓, *LDL↓, COX2↓, Hif1a↓, *Aβ↓, *tau↓, *toxicity↓,
3890- Cin,    The Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases
- Review, NA, NA
*cardioP↑, *Inflam↓, *ROS↓, *lipid-P↓, *AntiAg↑, *angioG↑, *GutMicro↑, *ER Stress↓,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *eff↑, *LDL↓, *HDL↑, *eff↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
4763- CoQ10,  Chemo,  doxoR,    Effect of Coenzyme Q10 on Doxorubicin Cytotoxicity in Breast Cancer Cell Cultures
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549
ChemoSen∅, antiNeop∅, *cardioP↑, Dose↝, selectivity↑, TumCG∅, TumCG∅, Apoptosis∅,
4767- CoQ10,    Efficacy of Coenzyme Q10 for Improved Tolerability of Cancer Treatments: A Systematic Review
- Review, Var, NA
chemoP↑, cardioP↑, hepatoP↑, eff↝,
4768- CoQ10,    Role of coenzymes in cancer metabolism
- Review, Var, NA
Risk↓, *ROS↓, AntiCan↑, TumMeta↓, ROS↑, TumCG↓, Apoptosis↑, TumMeta↓, Wnt↓, β-catenin/ZEB1↓, TumCG↓, selectivity↑, RadioS↑, ChemoSen↑, H2O2↓, MMP2↓, cardioP↑, ChemoSen∅, Dose↝,
4769- CoQ10,    CoQ10 Is Key for Cellular Energy and Cancer Support
- Review, Var, NA
Risk↓, TumCG↓, angioG↓, TumCD↑, *toxicity↓, *BioAv↑, MMPs↓, Inflam↓, chemoP↑, cardioP↑, *ROS↓, *toxicity↝, Dose?,
5780- CRMs,  HCAs,  RES,  Sper,  ASA  Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential
- Review, Var, NA
*OS↑, *AntiAge↑, *cardioP↑, *neuroP↑, AntiCan↑, *TNF-α↓, *Weight↓, *BP↓, *Inflam↓, *Insulin↓, *ROS↓, *AMPK↑, *mTOR↓, *SIRT1↑, CRM↑,
2818- CUR,    Novel Insight to Neuroprotective Potential of Curcumin: A Mechanistic Review of Possible Involvement of Mitochondrial Biogenesis and PI3/Akt/ GSK3 or PI3/Akt/CREB/BDNF Signaling Pathways
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *Apoptosis↓, *cognitive↑, *cardioP↑, other↑, *COX2↓, *IL1β↓, *TNF-α↓, NF-kB↓, *PGE2↓, *iNOS↓, *NO↓, *IL2↓, *IL4↓, *IL6↓, *INF-γ↓, *GSK‐3β↓, *STAT↓, *GSH↑, *MDA↓, *lipid-P↓, *SOD↑, *GPx↑, *Catalase↑, *GSR↓, *LDH↓, *H2O2↓, *Casp3↓, *Casp9↓, *NRF2↑, *AIF↓, *ATP↑,
5071- dietSTF,    Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review
- Review, Var, NA - Review, AD, NA
Risk↓, TumCMig↓, IGF-1↓, TumAuto↑, Inflam↓, ChemoSen↑, Apoptosis↑, chemoP↑, *glucose↓, *AntiDiabetic↑, *cardioP↑, *LDL↓, *BP↓, *neuroP↑, *cognitive↑, *memory↑, *OS↑, *QoL↑, Imm↑, TumCG↓, ChemoSideEff↓, QoL↑,
4987- Dipy,  ATV,    Enhanced cardioprotection against ischemia-reperfusion injury with a dipyridamole and low-dose atorvastatin combination
- in-vivo, Nor, NA
*cardioP↑, *Akt↑, *eNOS↑,
1607- EA,    Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions
- Review, GC, NA
STAT3↓, TumCP↓, Apoptosis↑, NF-kB↓, EMT↓, RadioS↑, antiOx↑, COX1↓, COX2↓, cMyc↓, Snail↓, Twist↓, MMP2↓, P90RSK↓, CDK8↓, PI3K↓, Akt↓, TumCCA↑, Casp8↑, PCNA↓, TGF-β↓, Shh↓, NOTCH↓, IL6↓, ALAT↓, ALP↓, AST↓, VEGF↓, P21↑, *toxicity∅, *Inflam↓, *cardioP↑, *neuroP↑, *hepatoP↑, ROS↑, *NRF2↓, *GSH↑,
3231- EGCG,    Epigallocatechin-3-gallate restores mitochondrial homeostasis impairment by inhibiting HDAC1-mediated NRF1 histone deacetylation in cardiac hypertrophy
- in-vitro, Nor, NA
*HDAC↓, *cardioP↑, *Nrf1↑, *PGC-1α↓,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
3205- EGCG,    The Role of Epigallocatechin-3-Gallate in Autophagy and Endoplasmic Reticulum Stress (ERS)-Induced Apoptosis of Human Diseas
- Review, Var, NA - Review, AD, NA
Beclin-1↑, ROS↑, Apoptosis↑, ER Stress↑, *Inflam↓, *cardioP↑, *antiOx↑, *LDL↓, *NF-kB↓, *MPO↓, *glucose↓, *ROS↓, ATG5↑, LC3B↑, MMP↑, lactateProd↓, VEGF↓, Zeb1↑, Wnt↑, IGF-1R↑, Fas↑, Bak↑, BAD↑, TP53↓, Myc↓, Casp8↓, LC3II↑, NOTCH3↓, eff↑, p‑Akt↓, PARP↑, *Cyt‑c↓, *BAX↓, *memory↑, *neuroP↑, *Ca+2?, GRP78/BiP↑, CHOP↑, ATF4↑, Casp3↑, Casp8↑, UPR↑,
3211- EGCG,    Antioxidation Function of EGCG by Activating Nrf2/HO-1 Pathway in Mice with Coronary Heart Disease
- in-vivo, NA, NA
*cardioP↑, *VEGF↓, *MMP2↓, *SOD↑, *ROS↓, *HO-1↑, *NQO1↑, *NRF2↑,
2302- EGCG,    Flavonoids Targeting HIF-1: Implications on Cancer Metabolism
- Review, Var, NA
TumCP↓, Hif1a↓, LDHA↓, PFK↓, cardioP↑, Glycolysis↓, PKM2↓,
2563- EGCG,    Cardioprotective effect of epigallocatechin gallate in myocardial ischemia/reperfusion injury and myocardial infarction: a meta-analysis in preclinical animal studies
- Review, NA, NA
cardioP↑, ROS↑, AntiAg↑, eff↑, COX1↓,
5227- EMD,    Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy
- vitro+vivo, Nor, NA
*cardioP↑, HDAC↓, HDAC1↓, HDAC2↓, ac‑H3↑, Dose↝, BioAv↓,
3710- FA,    Therapeutic Potential of Ferulic Acid in Alzheimer's Disease
- Review, AD, NA
*antiOx↑, *AntiCan↑, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *Aβ↓, *ROS↓, *AChE↓,

Showing Research Papers: 51 to 100 of 202
Prev Page 2 of 5 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 202

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   CYP1A1↓, 1,   H2O2↓, 1,   HO-1↓, 1,   HO-1↑, 1,   lipid-P↑, 1,   NADH↓, 1,   NRF2↓, 2,   NRF2↑, 1,   ROS↑, 12,  

Mitochondria & Bioenergetics ⓘ

ADP:ATP↑, 1,   MEK↓, 1,   mitResp↓, 1,   MMP↓, 6,   MMP↑, 2,   MPT↑, 1,   mtDam↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 3,   cMyc↓, 2,   CRM↑, 1,   GlucoseCon↓, 1,   GlutMet↓, 1,   Glycolysis↓, 3,   HK2↓, 3,   lactateProd↓, 2,   LDH↓, 1,   LDHA↓, 1,   LDL↓, 1,   PDK1↓, 1,   PFK↓, 1,   PIK3CA↓, 1,   PKM2↓, 1,   PPARα↓, 1,   SIRT1↓, 1,  

Cell Death ⓘ

Akt↓, 5,   p‑Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 11,   Apoptosis∅, 1,   BAD↑, 2,   Bak↑, 2,   BAX↑, 3,   Bax:Bcl2↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 2,   Casp↑, 1,   Casp3↑, 7,   Casp8↓, 1,   Casp8↑, 3,   Casp9↑, 3,   Cyt‑c↑, 5,   Fas↑, 1,   FasL↑, 1,   HGF/c-Met↓, 1,   hTERT/TERT↓, 3,   iNOS↓, 1,   JNK↑, 1,   MAPK↓, 3,   Mcl-1↓, 1,   Myc↓, 1,   p38↑, 1,   Telomerase↓, 1,   TumCD↑, 1,  

Transcription & Epigenetics ⓘ

ac‑H3↑, 1,   other↑, 1,   tumCV↓, 2,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   eIF2α↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 4,   GRP78/BiP↑, 2,   GRP78/BiP↝, 1,   PERK↑, 1,   UPR↑, 4,   XBP-1↓, 1,  

Autophagy & Lysosomes ⓘ

ATG5↑, 1,   Beclin-1↑, 1,   LC3B↑, 1,   LC3II↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 2,   DNMTs↓, 1,   P53↑, 1,   p‑P53↑, 1,   PARP↑, 4,   PCNA↓, 2,   TP53↓, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 5,   P21↑, 2,   TumCCA↑, 5,  

Proliferation, Differentiation & Cell State ⓘ

CDK8↓, 1,   EMT↓, 3,   EMT↝, 1,   ERK↓, 4,   Gli1↓, 1,   p‑GSK‐3β↓, 1,   HDAC↓, 3,   HDAC1↓, 1,   HDAC2↓, 1,   IGF-1↓, 1,   IGF-1R↑, 1,   Let-7↑, 1,   mTOR↓, 3,   NOTCH↓, 3,   NOTCH1↑, 2,   NOTCH3↓, 1,   P90RSK↓, 1,   PI3K↓, 5,   PTEN↑, 1,   Shh↓, 1,   SHP1↑, 1,   Smo↓, 1,   STAT3↓, 2,   p‑STAT3↓, 1,   TOP1↓, 2,   TOP2↓, 1,   TRPM7↓, 2,   TumCG↓, 6,   TumCG∅, 2,   Wnt↓, 1,   Wnt↑, 1,   Wnt/(β-catenin)↓, 1,  

Migration ⓘ

AntiAg↑, 1,   Ca+2↑, 3,   CLDN1↓, 1,   p‑Cofilin↑, 1,   E-cadherin↑, 3,   F-actin↓, 1,   Fibronectin↓, 1,   MMP-10↓, 1,   MMP2↓, 6,   MMP9↓, 4,   MMPs↓, 2,   N-cadherin↓, 2,   PDGF↓, 1,   Slug↓, 1,   Snail↓, 2,   TET1↑, 2,   TGF-β↓, 1,   TIMP1↑, 2,   TIMP2↑, 1,   TRIB3↑, 1,   TumCI↓, 1,   TumCMig↓, 3,   TumCP↓, 4,   TumMeta↓, 3,   Twist↓, 3,   uPA↓, 1,   Vim↓, 1,   Zeb1↑, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature ⓘ

angioG↓, 4,   ATF4↑, 2,   EGFR↓, 2,   Hif1a↓, 7,   VEGF↓, 7,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 2,   COX2↓, 4,   COX2↑, 1,   IL10↓, 1,   IL1β↓, 2,   IL6↓, 5,   Imm↑, 1,   Inflam↓, 3,   NF-kB↓, 4,   PD-L1↓, 1,   PGE2↓, 2,   TLR4↓, 1,   TNF-α↓, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 5,   BioAv↝, 3,   ChemoSen↑, 8,   ChemoSen∅, 2,   Dose?, 1,   Dose↝, 3,   eff↓, 1,   eff↑, 13,   eff↝, 2,   eff∅, 1,   Half-Life↓, 1,   Half-Life↝, 1,   RadioS↑, 4,   selectivity↑, 3,  

Clinical Biomarkers ⓘ

ALAT↓, 3,   ALP↓, 2,   AST↓, 1,   EGFR↓, 2,   hTERT/TERT↓, 3,   IL6↓, 5,   LDH↓, 1,   Myc↓, 1,   PD-L1↓, 1,   TP53↓, 1,   TRIB3↑, 1,  

Functional Outcomes ⓘ

AntiCan↓, 1,   AntiCan↑, 5,   AntiDiabetic↑, 1,   antiNeop∅, 1,   cardioP↑, 8,   chemoP↑, 6,   ChemoSideEff↓, 1,   hepatoP↑, 1,   neuroP↑, 2,   Obesity↓, 1,   OS↑, 1,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 3,   toxicity↓, 1,  
Total Targets: 214

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

TMAO↑, 1,  

Redox & Oxidative Stress ⓘ

antiOx↑, 18,   Catalase↑, 8,   Ferroptosis↓, 2,   GPx↑, 5,   GPx4↑, 1,   GSH↑, 7,   GSR↓, 1,   GSR↑, 1,   GSTs↑, 1,   H2O2↓, 1,   HDL↑, 1,   HO-1↓, 1,   HO-1↑, 6,   Iron↑, 1,   lipid-P↓, 7,   MDA↓, 7,   MPO↓, 1,   NOX4↓, 1,   NQO1↑, 2,   Nrf1↑, 1,   NRF2↓, 2,   NRF2↑, 11,   RNS↓, 1,   ROS↓, 27,   SOD↑, 11,   SOD1↑, 1,   SOD2↑, 1,   TAC↑, 2,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics ⓘ

AIF↓, 1,   ATP↑, 2,   Insulin↓, 1,   PGC-1α↓, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 2,   GAPDH↑, 1,   glucose↓, 3,   LDH↓, 4,   LDL↓, 4,   lipidLev↓, 2,   NADPH↓, 2,   PPARα↑, 1,   PPARα↝, 1,   SIRT1↑, 1,  

Cell Death ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↓, 1,   BAX↓, 2,   Bcl-2↑, 1,   Casp↓, 1,   Casp3↓, 3,   Casp9↓, 1,   Cyt‑c↓, 2,   Ferroptosis↓, 2,   iNOS↓, 3,   JNK↓, 2,   MAPK↓, 1,   MCT1↓, 1,   necrosis↓, 1,   TRPV1↑, 2,  

Kinase & Signal Transduction ⓘ

TRPV3↑, 1,  

Transcription & Epigenetics ⓘ

other↓, 3,   other↑, 5,   other↝, 2,   other∅, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,   HSP70/HSPA5↑, 1,  

DNA Damage & Repair ⓘ

DNMT1↓, 1,   P53↓, 1,   PARP↓, 1,   PCNA↓, 1,  

Cell Cycle & Senescence ⓘ

E2Fs↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

GSK‐3β↓, 1,   p‑GSK‐3β↑, 1,   HDAC↓, 1,   IGF-1↑, 1,   IGF-1R↓, 1,   IGFBP1↑, 1,   mTOR↓, 1,   PI3K↓, 1,   STAT↓, 1,   TRPM7↓, 2,  

Migration ⓘ

5LO↓, 3,   AntiAg↑, 9,   AP-1↓, 1,   Ca+2?, 1,   Ca+2↓, 1,   Ca+2↑, 2,   MMP2↓, 2,   PKCδ↑, 1,   TRPC1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↑, 1,   eNOS↑, 1,   Hif1a↓, 1,   NO↓, 2,   PDGFR-BB↓, 1,   TXA2↓, 1,   VEGF↓, 2,  

Barriers & Transport ⓘ

BBB↓, 1,   BBB↑, 4,   GastroP↑, 2,   IBI↑, 1,   OCLN↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 10,   CRP↓, 1,   IL1β↓, 4,   IL2↓, 2,   IL4↓, 1,   IL6↓, 5,   IL8↓, 1,   Imm↑, 2,   INF-γ↓, 1,   Inflam↓, 30,   JAK↓, 1,   NF-kB↓, 11,   PGE2↓, 2,   TLR2↓, 1,   TLR4↓, 2,   TNF-α↓, 9,  

Synaptic & Neurotransmission ⓘ

AChE↓, 6,   BChE↓, 2,   BDNF↑, 1,   tau↓, 2,  

Protein Aggregation ⓘ

Aβ↓, 7,   NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 9,   BioAv↑, 10,   BioAv⇅, 2,   BioAv↝, 5,   Dose↝, 7,   eff↑, 10,   Half-Life↓, 1,   Half-Life↝, 1,  

Clinical Biomarkers ⓘ

AST↓, 2,   BP↓, 9,   CRP↓, 1,   GutMicro↑, 5,   IL6↓, 5,   LDH↓, 4,  

Functional Outcomes ⓘ

AntiAge↑, 2,   AntiCan↑, 5,   AntiDiabetic↑, 7,   cardioP↑, 41,   cardioP⇅, 1,   cardioP∅, 1,   chemoP↑, 1,   chemoPv↑, 4,   cognitive↓, 1,   cognitive↑, 10,   hepatoP↓, 1,   hepatoP↑, 12,   memory↑, 7,   memory∅, 1,   motorD↑, 1,   neuroP↓, 1,   neuroP↑, 25,   Obesity↓, 5,   OS↑, 4,   Pain↓, 4,   QoL↑, 2,   RenoP↑, 5,   Risk↓, 3,   toxicity↓, 6,   toxicity↝, 1,   toxicity∅, 1,   Weight↓, 2,  

Infection & Microbiome ⓘ

Bacteria↓, 7,   Diar↓, 1,  
Total Targets: 168

Scientific Paper Hit Count for: cardioP, cardioProtective
11 doxorubicin
11 Lycopene
11 Quercetin
11 Thymoquinone
9 Allicin (mainly Garlic)
9 Resveratrol
8 Chlorogenic acid
7 Carvacrol
6 Baicalein
6 Berberine
6 EGCG (Epigallocatechin Gallate)
5 Alpha-Lipoic-Acid
5 Chrysin
5 Coenzyme Q10
5 Honokiol
4 Aspirin -acetylsalicylic acid
4 Atorvastatin
4 Chocolate
4 Sulforaphane (mainly Broccoli)
4 Silymarin (Milk Thistle) silibinin
3 Ashwagandha(Withaferin A)
3 Astaxanthin
3 Thymol-Thymus vulgaris
3 Choline
3 Cinnamon
3 Spermidine
3 Hydrogen Gas
3 Magnetic Fields
3 Rosmarinic acid
3 Urolithin
3 Vitamin K2
2 Baicalin
2 Capsaicin
2 Selenium
2 Chemotherapy
2 Ferulic acid
2 Fisetin
2 Luteolin
2 Magnolol
2 Metformin
2 Piperine
2 Pterostilbene
2 Shikonin
1 Anthocyanins
1 Astragalus
1 Apigenin (mainly Parsley)
1 Artemisinin
1 Aloe anthraquinones
1 Berbamine
1 Biochanin A
1 bempedoic acid
1 Betulinic acid
1 Boron
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Calorie Restriction Mimetics
1 Hydroxycinnamic-acid
1 Curcumin
1 diet Short Term Fasting
1 Dipyridamole
1 Ellagic acid
1 Emodin
1 Melatonin
1 Moringa oleifera
1 nicotinamide adenine dinucleotide
1 Naringin
1 Phenylbutyrate
1 Propolis -bee glue
1 Piperlongumine
1 Psoralidin
1 Rutin
1 Selenium NanoParticles
1 Shankhpushpi
1 Taurine
1 Ursolic acid
1 Vitamin B3,Niacin
1 Vitamin E
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1188  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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