Imm Cancer Research Results

Imm, immunostimulatory: Click to Expand ⟱
Source:
Type:
Enhance the immune response in patients.


Scientific Papers found: Click to Expand⟱
5997- Chit,    Using immunoadjuvant agent glycated chitosan to enhance anti-cancer stem like cell immunity induced by HIFU
- in-vivo, Lung, NA
Imm↑, TumMeta↓, eff↑,
5994- Chit,    Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action
- Review, Var, NA
angioG↓, *Imm↑, *antiOx↑, selectivity↑, other↝, toxicity↓, BioAv↑, eff↝, Half-Life↑, MPT↑, MMP9↓, lipid-P↑, EPR↑, NK cell↑, Casp3↑, Casp8↑, TumCCA↑, ROS↑, DDS↑, VEGF↓, TIMP1↑, ChemoSen↑, eff↑,
5993- Chit,    In vivo stepwise immunomodulation using chitosan nanoparticles as a platform nanotechnology for cancer immunotherapy
- in-vitro, Var, NA
Imm↑,
5990- Chit,    Chitosan Nanoparticles for Targeted Cancer Therapy: A Review of Stimuli-Responsive, Passive, and Active Targeting Strategies
- Review, Var, NA
DDS↑, eff↓, *Bacteria↓, *antiOx↑, *Wound Healing↑, *Imm↑, TumCP↓, TumMeta↓, angioG↓, Apoptosis↑, ROS↑, ER Stress↑, BioAv↑, Half-Life↑, eff↑, EPR↑, ChemoSen↑, eff↑,
6071- CHL,    First-in-human clinical trial of high-dose sodium copper chlorophyllin: Pharmacology and efficacy as a dual immunomodulatory/antiviral agent
- Trial, Nor, NA
*Dose↑, *toxicity↓, *Imm↑,
6084- CHOC,    Cocoa Polyphenols and Their Potential Benefits for Human Health
- Review, Nor, NA - Review, Stroke, NA - Review, IBD, NA
*lipid-P↓, *ROS↓, *Inflam↓, *BP↓, *cardioP↑, *chemoPv↑, *BioAv⇅, *antiOx↑, *Risk↓, *5LO↓, *AntiAg↑, *Imm↑, *NF-kB↓, *other↓, CYP1A1↓, COX2↓, *Obesity↓, *cognitive↑,
6370- CPLE,    Delving into the Therapeutic Potential of Carica papaya Leaf against Thrombocytopenia
- Review, Var, NA
CIT↓, *Imm↑, *AntiDiabetic↑, *AntiCan↑, angioG↓, *Bacteria↓, *antiOx↑,
6374- CPLE,    Antiviral & platelet-protective properties of Carica papaya in dengue
- Review, Nor, NA
*antiOx↑, *lipid-P↓, *AntiTum↑, Imm↑, CIT↓,
6520- CRV,    Health Benefits and Pharmacological Properties of Carvone
- Review, Nor, NA
*Bacteria↓, *AntiFungal↑, *antiOx↑, *Inflam↓, AntiCan↑, *AntiDiabetic↑, *Obesity↓, TumCCA↑, *AntiArt↑, Imm↑, *P450↓, *GSR↑, GSTs↑, GSH↑, BAX↑, Casp3↑, TumCP↓, TumCMig↓, Apoptosis↑,
6202- Cuc,    Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms
- Review, Var, NA
*Inflam↓, *antiOx↑, *hepatoP↑, AntiTum↑, AntiCan↑, *chemoPv↑, *AntiDiabetic↑, *Imm↑, Hif1a↓, P-gp↓, mTORC1↓, ERK↓, Akt↓, Casp3↑, Casp7↑, ATP↓, RadioS↑, ChemoSen↑,
6203- Cuc,  immuno,    Isocucurbitacin B targets STAT3 to induce ferroptosis and promote anti-PD1 immunotherapy responses in breast cancer
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549 - in-vivo, BC, 4T1
Ferroptosis↑, STAT3↓, GPx4↓, Imm↑, PD-L1↓, TumCG↓, ATP↓, OXPHOS↓,
6214- CUR,    Curcumin Nanoparticles-related Non-invasive Tumor Therapy, and Cardiotoxicity Relieve
TumCD↓, TumCI↓, *Inflam↓, *antiOx↓, *AntiTum↓, NF-kB↓, COX2↓, Casp9↓, ROS↑, BioAv↑, RadioS↑, ChemoSen↑, Imm↑, PhotoS↑, sonoS↑, 5LO↓, iNOS↓, IL2↓, TNF-α↓, Casp9↑, Casp3↑, Bcl-2↓, BAX↑, Apoptosis↑, ER Stress↑, cycD1/CCND1↓, CDK2↓, CycB/CCNB1↓, TumCCA↑, MMPs↓, *radioP↑, chemoP↑, hepatoP↑, cardioP↑, eff↑, PhotoS↑, eff↑, ROS↑, GSH↓,
6223- CUR,    Curcumin Rewires the Tumor Metabolic Landscape: Mechanisms and Clinical Prospects
- Review, Var, NA
Ferroptosis↑, GutMicro↑, Akt↓, mTOR↓, NF-kB↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, TumCP↓, TumCI↓, TumMeta↓, AMPK↑, P53↑, NRF2↑, TumCCA↑, Apoptosis↑, Casp↑, GPx4↓, DNMTs↓, HDAC↓, VEGF↓, Imm↑, NK cell↑, Warburg↓, Hif1a↓, HK2↓, PKM2↓, LDHA↓, GLUT1↓, MCT1↓, AMPK↑, FASN↓, SCD1↓, GLS↓, Apoptosis↑, ETC↓, MMP↓, ROS↑, lipid-P↑, ChemoSen↑, PDK1↓, Beclin-1↓, ATP↓, Glycolysis↓, GlucoseCon↓, lactateProd↑, MMPs↓, GSH↓, G6PD↓, OXPHOS↓, SREBP2↓, COX2↓, AP-1↓, NADH↓, NRF2↑, HO-1↑, Iron↑, MDA↑, *ROS↓, *Inflam↓,
6221- CUR,    Oxidative Stress and Cancer: Harnessing the Therapeutic Potential of Curcumin and Analogues Against Cancer
- Review, Var, NA
NF-kB↓, Imm↑, *TAC↑, *MDA↓, ROS↑, TumAuto↑, TumCCA↑, Keap1↑, ChemoSen↑, ER Stress↑, eff↓, TrxR↓, STAT3↓, *BioAv↓,
5065- dietSTF,  dietFMD,    Nutrition, GH/IGF-I Signaling, and Cancer
- Review, Var, NA
GH↓, IGF-1↓, glucose↓, IGFBP1↑, OS↑, Imm↑, neuroP↑, BMD↑, Dose↝, Risk↓, other↑, TumCP↓,
5071- dietSTF,    Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review
- Review, Var, NA - Review, AD, NA
Risk↓, TumCMig↓, IGF-1↓, TumAuto↑, Inflam↓, ChemoSen↑, Apoptosis↑, chemoP↑, *glucose↓, *AntiDiabetic↑, *cardioP↑, *LDL↓, *BP↓, *neuroP↑, *cognitive↑, *memory↑, *OS↑, *QoL↑, Imm↑, TumCG↓, ChemoSideEff↓, QoL↑,
6288- DL,    From Citrus to Clinic: Limonene’s Journey Through Preclinical Research, Clinical Trials, and Formulation Innovations
- Review, Var, NA - Review, AD, NA
other↑, DDS↑, *antiOx↑, *Inflam↓, *AntiDiabetic↑, *neuroP↑, *Imm↑, *Wound Healing↑, *other↑, *BioAv↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *DNAdam↓, *AntiDiabetic↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↓, *AChE↓, *BChE↓, *Aβ↓, *ROS↓, *toxicity?,
6348- DRE,    New prospects in oncotherapy: bioactive compounds from Taraxacum officinale
- Review, Var, NA
Dose↝, TumCP↓, toxicity↓, *AntiDiabetic↑, *antiOx↑, *hepatoP↑, *diuretic↑, *Inflam↓, *neuroP↑, *Imm↑, eff↑, Apoptosis↑, tumCV↓, selectivity↑, TumCMig↓, EMT↓, MMP2↓, MMP9↓, Wnt↓, β-catenin/ZEB1↓, PI3K↓, Akt↓, JNK↓, ERK↓,
6357- DRE,    New Perspectives on the Effect of Dandelion, Its Food Products and Other Preparations on the Cardiovascular System and Its Diseases
- Review, Nor, NA
*cardioP↑, *Dose↝, *Dose↝, *toxicity∅, *toxicity↓, *BP↓, *Inflam↓, *Bacteria↓, *Imm↑, *lipid-P↓, *AST↓, *ALAT↓, *AntiAg↑, *ROS↓, *AntiThr↑,
6354- DRE,    Taraxacum officinale L. in leukemia and lymphoma: current knowledge and prospects for horticulture
- Review, AML, NA
ROS↑, mt-Apoptosis↑, TumCCA↑, PI3K↓, Akt↓, STAT3↓, Dose↝, *hepatoP↑, Casp8↑, mtDam↑, TumCD↑, selectivity↑, DNAdam↑, BAX↑, P53↑, Bcl-2↓, CSCs↓, *toxicity↓, tumCV↓, Imm↑, FAK↓, mTOR↓, ChemoSen↑, eff↝, eff↑,
6365- DRE,    AN OVERVIEW OF THERAPEUTIC POTENTIALS OF TARAXACUM OFFICINALE (DANDELION): A TRADITIONALLY VALUABLE HERB WITH A REACH HISTORICAL BACKGROUND
- Review, Var, NA
*Inflam↓, *AntiTum↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *diuretic↑, *RenoP↑, *hepatoP↑, *neuroP↑, AntiTum↑, TNF-α↑, IL1β↑, Apoptosis↑, MMP2↓, MMP9↑, eff↑, Diff↑, *ROS↓, *HO-1↑, *NRF2↑, *lipid-P↓,
6362- DRE,    Taraxacum spp. in vitro and in vivo anticancer activity – A review
- Review, Var, NA
tumCV↓, *AntiDiabetic↑, *Imm↑,
6366- DRE,    A comprehensive review of the benefits of Taraxacum officinale on human health
- Review, Var, NA
*diuretic↑, *hepatoP↑, *Imm↑, *Bacteria↓, *AntiArt↑, *AntiDiabetic↑, *Obesity↓, *antiOx↓, *AntiCan↑, Dose?,
4914- DSF,  immuno,    Disulfiram and cancer immunotherapy: Advanced nano-delivery systems and potential therapeutic strategies
- Review, Var, NA
AntiTum↑, eff↑, ALDH↓, Dose↝, RadioS↑, angioG↓, TumMeta↓, BioAv↝, ROS↑, DNAdam↑, P-gp↓, CSCs↓, EMT↓, Imm↑, SOD↓, MAPK↓, NF-kB↓, ChemoSen↑, eff↑, toxicity↝, BioAv↑, *Inflam↓, Sepsis↓,
4916- DSF,  Cu,    The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics
- Review, Var, NA
TumCP↓, TumCMig↓, TumCI↓, eff↑, Imm↑, ROS↑, NF-kB↓, chemoP↑, JNK↑, FOXO↑, Myc↑, TumCCA↑, Apoptosis↑, RadioS↑, PD-L1↑, eff↑, CSCs↓, Dose↝, Half-Life↑,
6603- Ech,  doxoR,    The effect of Echinacea purpurea on the pharmacokinetics of docetaxel
- Trial, Var, NA
other∅, other↝, Imm↑, CYP3A4⇅, other↑,
6605- Ech,    Bioavailability of Echinacea Constituents: Caco-2 Monolayers and Pharmacokinetics of the Alkylamides and Caffeic Acid Conjugates
- Human, Nor, NA
*Imm↑,
5256- EP,    Pulsed electric fields: a sharp sword in the battle against cancers
- Review, Var, NA
BioAv↑, TumCD↑, MMP↓, Apoptosis↑, TumCCA↑, Imm↑, RadioS↑, ChemoSen↑,
5487- EP,    High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas
- in-vivo, GBM, NA
OS↑, CellMemb↑, Imm↑, Inflam↓, necrosis↑, Pyro↑, eff↑, IL2↑, IL6↑, IL17↑, IFN-γ↓,
5490- EP,    Application of Pulsed Electric Fields to Cancer Therapy
- Review, Var, NA
CellMemb↑, Ca+2↑, Imm↑, TumMeta↓,
5492- EP,    Nano-Pulse Stimulation Therapy in Oncology
- in-vivo, PC, Panc02 - in-vivo, BC, 4T1
CellMemb↑, Ca+2↑, DNAdam↑, eff↝, Imm↑,
5493- EP,    Schottky nanodiodes array enabled triboelectric nanosecond pulse generator for ultralow-cost tumor therapy
- Review, Var, NA
other↝, other↝, Ca+2↑, TumCD↑, Imm↑, TumCG↓, other↓,
5519- EP,    Nanosecond Pulsed Electric Fields (nsPEFs) for Precision Intracellular Oncotherapy: Recent Advances and Emerging Directions
- Review, Var, NA
MMP↓, Ca+2↑, eff↑, ER Stress↑, selectivity↑, CSCs↓, CD44↓, CD133↓, ROS↑, Imm↑, DNAdam↑, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp9↑, TumCD↑, Fas↑, UPR↑, Dose↝, Dose↝, Dose↓, Dose↑, HMGB1↓, eff↑, EPR↑, ChemoSen↑, ETC↝, *AntiAge↑, *Hif1a↑, *SIRT1↑,
5800- MET,    Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect
- Review, Var, NA
ChemoSen↑, RadioS↑, Imm↑, *AntiDiabetic↑, *AMPK↑, TumCP↓, hepatoP↑, ATP↓, AMP↑, glucoNG↓, ROS↑, compI↓, DNAdam↑, CSCs↓, NP/CIPN↓, chemoP↑, toxicity↓, Trx↓, eff↑, cycD1/CCND1↓, CDK4↓, CDK6↓, cycE/CCNE↓, CDK2↓,
200- MFrot,  MF,    Moderate intensity low frequency rotating magnetic field inhibits breast cancer growth in mice
- in-vivo, BC, MDA-MB-231 - in-vivo, BC, MCF-7
ALAT↓, TumVol↓, TumCCA↑, TumCG↓, TumMeta↓, Imm↑, P53↑, ALAT↓, AST↓,
198- MFrot,  MF,    Biological effects of rotating magnetic field: A review from 1969 to 2021
- Review, Var, NA
AntiCan↑, breath↑, Pain↓, Appetite↑, Strength↑, BowelM↑, TumMeta↓, TumCCA↑, ETC↓, MMP↓, TumCD↑, selectivity↑, ROS↑, Casp3↑, TumCG↓, TumCCA↑, ChrMod↑, TumMeta↓, Imm↑, DCells↑, Akt↓, OS⇅, toxicity↓, QoL↑, hepatoP↑, Pain↓, Weight↑, Strength↑, Sleep↑, IL6↓, CD4+↑, CD8+↑, Ca+2↑, radioP↑, chemoP↑, *BMD↑, *AntiAge↑, *AMPK↑, *P21↓, *P53↓, *mTOR↓, *OS↑, *β-Endo↑, *5HT↓,
5611- NaHCO3,    NaHCO3 enhances the antitumor activities of cytokine-induced killer cells against hepatocellular carcinoma HepG2 cells
- vitro+vivo, HCC, HepG2
tumCV↓, TumCG↓, pH↑, eff↑, Imm↑,
5617- NaHCO3,    Microenvironmental alkalization promotes the therapeutic effects of MSLN-CAR-T cells
- vitro+vivo, NA, NA
Imm↑, eff↑, pH↑,
5612- NaHCO3,  immuno,    Neutralization of tumor acidity improves anti-tumor responses to immunotherapies
- vitro+vivo, Var, B16-F10
Imm↑, eff↑, e-pH↑, TumCG↓, TumMeta↓, eff↑,
5610- NaHCO3,  doxoR,    Sodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin
- vitro+vivo, BC, 4T1
pH↑, Imm↑, eff↑, ChemoSen↑, TumVol↓, eff↑,
5608- NaHCO3,    Sodium Bicarbonate Nanoparticles for Amplified Cancer Immunotherapy by Inducing Pyroptosis and Regulating Lactic Acid Metabolism
- Study, Var, NA
TumCG↓, TumMeta↓, e-pH↑, Pyro↑, Imm↑, Na+↑,
5604- NaHCO3,    Mitochondrial metabolic reprogramming of macrophages and T cells enhances CD47 antibody-engineered oncolytic virus antitumor immunity
- vitro+vivo, Melanoma, B16-BL6 - in-vitro, BC, 4T1
eff↑, eff↑, TumMeta↓, pH↑, CaMKII ↑, CREB↑, PGC-1α↑, AntiTum↑, Imm↑, CD8+↑, TAMS↑,
5936- P,    The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data
- Review, IBD, NA
*Pain↓, *other↝, *Bacteria↓, *Inflam↓, *Imm↑, *eff↑, *toxicity↓,
5209- PI,    Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP-9 signaling pathway in DU145 cells
- in-vitro, Pca, DU145
TumCP↓, TumCMig↓, Apoptosis↑, p‑Akt↓, MMP9↓, p‑mTOR↓, TumMeta↓, *antiOx↓, *Inflam↓, *hepatoP↑, *Imm↑, *AntiCan↑,
6220- Se,  CUR,  Rad,    Selenium-Curcumin-PEG Nanoparticles Radiosensitization for Intensity-Modulated Radiation Therapy of Lung Tumor Cells: In Vitro Synergistic Combination Therapy
- in-vitro, Lung, A549
RadioS↑, TumCD↑, ROS↑, Imm↑, angioG↓, BioAv↑, TumCP↓, Apoptosis↓, TumMeta↓,
4485- Se,    Selenium stimulates the antitumour immunity: Insights to future research
- Review, NA, NA
*antiOx↑, chemoPv↑, ROS↑, Imm↑, selenoP↑, *IL2↑, *IL4↑, *TNF-α↓, *TGF-β↓, *EMT↓, Risk↓, *GPx↑, *TrxR↑,
4608- SeNPs,    Selenium Nanoparticles for Biomedical Applications: From Development and Characterization to Therapeutics
- Review, Var, NA - NA, AD, NA
*toxicity↝, *toxicity↓, *other↝, ROS↑, *Dose↝, *selenoP↑, AntiCan↑, AntiTum↑, *Bacteria↓, *radioP↑, *BioAv↑, *Inflam↓, *Imm↑, ChemoSen↑, *AntiAg↑, selectivity↑, eff↑, other↝, *eff↑, *Aβ↓, *eff↑,
4603- SeNPs,    Therapeutic applications of selenium nanoparticles
- Review, Var, NA
AntiCan↑, Imm↑, *AntiDiabetic↑, *antiOx↑, *Inflam↓, ROS↑, ER Stress↑, DNAdam↑, *toxicity↓, *eff↑, *BioAv↑, selectivity↑, TumCCA↑, Risk↓, *lipid-P↓, *TNF-α↓, *CRP↓, TumMeta↓, angioG↓, selectivity↑, eff↑, *eff↑,
4742- SSE,    Antitumor Effects of Selenium
- Review, Var, NA - Review, Arthritis, NA - Review, Sepsis, NA
*antiOx↓, *Inflam↓, Risk↓, TumCI↓, TumMeta↓, radioP↑, chemoP↑, Apoptosis↑, ROS↑, DNAdam↑, Dose↑, selectivity↑, *other↓, *BioAv↑, ROS↑, MMP↓, Casp↑, *Imm↑, *Pain↓, Sepsis↓, MMP2↓, MMP9↓, *Half-Life↓,
5074- SSE,    Application of Sodium Selenite in the Prevention and Treatment of Cancers
- Review, Var, NA
Imm↑, angioG↑, DNArepair↑, NK cell↑, ROS↑, AntiCan↑, selectivity↑, ER Stress↑, TumAuto↑, necrosis↑, toxicity↝, Dose↑,

Showing Research Papers: 51 to 100 of 106
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 106

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned

CIT↓, 2,  

Redox & Oxidative Stress

compI↓, 1,   CYP1A1↓, 1,   Ferroptosis↑, 2,   GPx4↓, 2,   GSH↓, 2,   GSH↑, 1,   GSTs↑, 1,   HO-1↑, 1,   Iron↑, 1,   Keap1↑, 1,   lipid-P↑, 2,   MDA↑, 1,   NADH↓, 1,   NRF2↑, 2,   OXPHOS↓, 2,   ROS↑, 19,   selenoP↑, 1,   SOD↓, 1,   Trx↓, 1,   TrxR↓, 1,  

Mitochondria & Bioenergetics

ATP↓, 4,   ETC↓, 2,   ETC↝, 1,   MMP↓, 5,   MPT↑, 1,   mtDam↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis

ALAT↓, 2,   AMP↑, 1,   AMPK↑, 2,   CREB↑, 1,   CYP3A4⇅, 1,   FASN↓, 1,   G6PD↓, 1,   GLS↓, 1,   glucoNG↓, 1,   glucose↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   lactateProd↑, 1,   LDHA↓, 1,   PDK1↓, 1,   PKM2↓, 1,   SCD1↓, 1,   SREBP2↓, 1,   Warburg↓, 1,  

Cell Death

Akt↓, 5,   p‑Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 12,   mt-Apoptosis↑, 1,   BAX↑, 4,   Bcl-2↓, 3,   Casp↑, 2,   Casp3↑, 7,   Casp7↑, 1,   Casp8↑, 2,   Casp9↓, 1,   Casp9↑, 4,   Cyt‑c↑, 1,   Fas↑, 1,   Ferroptosis↑, 2,   iNOS↓, 1,   JNK↓, 1,   JNK↑, 1,   MAPK↓, 1,   MCT1↓, 1,   MOMP↑, 1,   Myc↑, 1,   necrosis↑, 2,   Pyro↑, 2,   TumCD↓, 1,   TumCD↑, 6,  

Kinase & Signal Transduction

CaMKII ↑, 1,  

Transcription & Epigenetics

BowelM↑, 1,   ChrMod↑, 1,   other↓, 1,   other↑, 3,   other↝, 5,   other∅, 1,   PhotoS↑, 2,   sonoS↑, 1,   tumCV↓, 4,  

Protein Folding & ER Stress

ER Stress↑, 6,   UPR↑, 1,  

Autophagy & Lysosomes

Beclin-1↓, 1,   TumAuto↑, 3,  

DNA Damage & Repair

DNAdam↑, 7,   DNArepair↑, 1,   DNMTs↓, 1,   P53↑, 3,  

Cell Cycle & Senescence

CDK2↓, 2,   CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   TumCCA↑, 12,  

Proliferation, Differentiation & Cell State

ALDH↓, 1,   CD133↓, 1,   CD44↓, 1,   CSCs↓, 5,   Diff↑, 1,   EMT↓, 2,   ERK↓, 2,   FOXO↑, 1,   GH↓, 1,   HDAC↓, 1,   IGF-1↓, 2,   IGFBP1↑, 1,   mTOR↓, 2,   p‑mTOR↓, 1,   mTORC1↓, 1,   PI3K↓, 2,   STAT3↓, 4,   TumCG↓, 8,   Wnt↓, 2,  

Migration

5LO↓, 1,   AP-1↓, 1,   Ca+2↑, 5,   FAK↓, 1,   MMP2↓, 3,   MMP9↓, 4,   MMP9↑, 1,   MMPs↓, 2,   Na+↑, 1,   TIMP1↑, 1,   TumCI↓, 4,   TumCMig↓, 5,   TumCP↓, 9,   TumMeta↓, 15,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature

angioG↓, 6,   angioG↑, 1,   EPR↑, 3,   Hif1a↓, 2,   TAMS↑, 1,   VEGF↓, 2,  

Barriers & Transport

CellMemb↑, 3,   GLUT1↓, 1,   Na+↑, 1,   P-gp↓, 2,  

Immune & Inflammatory Signaling

CD4+↑, 1,   COX2↓, 3,   DCells↑, 1,   HMGB1↓, 1,   IFN-γ↓, 1,   IL17↑, 1,   IL1β↑, 1,   IL2↓, 1,   IL2↑, 1,   IL6↓, 1,   IL6↑, 1,   Imm↑, 33,   Inflam↓, 2,   NF-kB↓, 5,   NK cell↑, 3,   PD-L1↓, 1,   PD-L1↑, 1,   TNF-α↓, 1,   TNF-α↑, 1,  

Cellular Microenvironment

pH↑, 4,   e-pH↑, 2,  

Hormonal & Nuclear Receptors

CDK6↓, 1,  

Drug Metabolism & Resistance

BioAv↑, 6,   BioAv↝, 1,   ChemoSen↑, 14,   DDS↑, 3,   Dose?, 1,   Dose↓, 1,   Dose↑, 3,   Dose↝, 7,   eff↓, 2,   eff↑, 27,   eff↝, 3,   Half-Life↑, 3,   RadioS↑, 7,   selectivity↑, 10,  

Clinical Biomarkers

ALAT↓, 2,   AST↓, 1,   BMD↑, 1,   GutMicro↑, 1,   IL6↓, 1,   IL6↑, 1,   Myc↑, 1,   PD-L1↓, 1,   PD-L1↑, 1,  

Functional Outcomes

AntiCan↑, 6,   AntiTum↑, 5,   Appetite↑, 1,   breath↑, 1,   cardioP↑, 1,   chemoP↑, 6,   chemoPv↑, 1,   ChemoSideEff↓, 1,   hepatoP↑, 3,   neuroP↑, 1,   NP/CIPN↓, 1,   OS↑, 2,   OS⇅, 1,   Pain↓, 2,   QoL↑, 2,   radioP↑, 2,   Risk↓, 5,   Sleep↑, 1,   Strength↑, 2,   toxicity↓, 4,   toxicity↝, 2,   TumVol↓, 2,   Weight↑, 1,  

Infection & Microbiome

CD8+↑, 2,   Sepsis↓, 2,  
Total Targets: 213

Pathway results for Effect on Normal Cells:


NA, unassigned

AntiArt↑, 2,   diuretic↑, 3,  

Redox & Oxidative Stress

antiOx↓, 4,   antiOx↑, 12,   Catalase↑, 1,   GPx↑, 1,   GSH↑, 1,   GSR↑, 1,   HO-1↑, 1,   lipid-P↓, 5,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 6,   selenoP↑, 1,   SOD↑, 1,   TAC↑, 1,   TrxR↑, 1,  

Core Metabolism/Glycolysis

ALAT↓, 1,   AMPK↑, 2,   glucose↓, 1,   LDL↓, 1,   SIRT1↑, 1,  

Transcription & Epigenetics

AntiThr↑, 1,   other↓, 2,   other↑, 1,   other↝, 2,  

DNA Damage & Repair

DNAdam↓, 1,   P53↓, 1,  

Cell Cycle & Senescence

P21↓, 1,  

Proliferation, Differentiation & Cell State

EMT↓, 1,   mTOR↓, 1,  

Migration

5LO↓, 1,   AntiAg↑, 3,   TGF-β↓, 1,   β-Endo↑, 1,  

Angiogenesis & Vasculature

Hif1a↑, 1,  

Immune & Inflammatory Signaling

CRP↓, 1,   IL2↑, 1,   IL4↑, 1,   Imm↑, 17,   Inflam↓, 15,   NF-kB↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission

5HT↓, 1,   AChE↓, 1,   BChE↓, 1,  

Protein Aggregation

Aβ↓, 2,  

Drug Metabolism & Resistance

BioAv↓, 1,   BioAv↑, 4,   BioAv⇅, 1,   Dose↑, 1,   Dose↝, 3,   eff↑, 5,   Half-Life↓, 1,   P450↓, 1,  

Clinical Biomarkers

ALAT↓, 1,   AST↓, 1,   BMD↑, 1,   BP↓, 3,   CRP↓, 1,  

Functional Outcomes

AntiAge↑, 2,   AntiCan↑, 3,   AntiDiabetic↑, 12,   AntiTum↓, 1,   AntiTum↑, 2,   cardioP↑, 3,   chemoPv↑, 2,   cognitive↑, 2,   hepatoP↑, 6,   memory↑, 1,   neuroP↑, 4,   Obesity↓, 3,   OS↑, 2,   Pain↓, 2,   QoL↑, 1,   radioP↑, 2,   RenoP↑, 1,   Risk↓, 1,   toxicity?, 1,   toxicity↓, 6,   toxicity↝, 1,   toxicity∅, 1,   Wound Healing↑, 2,  

Infection & Microbiome

AntiFungal↑, 1,   Bacteria↓, 7,  
Total Targets: 85

Scientific Paper Hit Count for: Imm, immunostimulatory
13 beta-glucans
9 chitosan
6 immunotherapy
6 Dandelion Root
6 Electrical Pulses
6 Bicarbonate(Sodium)
5 Selenite (Sodium)
4 Astragalus
4 Curcumin
3 Bifidobacterium
2 Aloe anthraquinones
2 Butyrate
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Cat’s Claw
2 Chlorogenic acid
2 Carica papaya leaf extract
2 Cucurbitacin
2 diet Short Term Fasting
2 Disulfiram
2 Echinacea
2 doxorubicin
2 Magnetic Field Rotating
2 Magnetic Fields
2 Selenium
2 Selenium NanoParticles
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Anethole/trans-Anethole
1 Aspirin
1 Astaxanthin
1 Bevacizumab (brand Avastin)
1 Bromelain
1 Boswellia (frankincense)
1 Black phosphorus
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Caffeic acid
1 Capsaicin
1 Carvacrol
1 Chemotherapy
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Celastrol
1 Chlorophyllin
1 Chocolate
1 Carvone
1 diet FMD Fasting Mimicking Diet
1 D-limonene
1 Copper and Cu NanoParticles
1 Metformin
1 Peppermint
1 Piperine
1 Radiotherapy/Radiation
1 Thymol-Thymus vulgaris
1 Urolithin
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1332  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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