Aβ Cancer Research Results

Aβ, Aβ aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (Aβ): In Alzheimer’s disease, Aβ peptides tend to misfold and aggregate into oligomers and fibrils.
Scientific Papers found: Click to Expand⟱
3872- Carno,    Carnosine Protects Macrophages against the Toxicity of Aβ1-42 Oligomers by Decreasing Oxidative Stress
- in-vitro, AD, NA
*antiOx↑, *Inflam↓, *Aβ↓, *neuroP↑, *ROS↓, *NO↓,
3869- Carno,    Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *IronCh↑, *AntiAge↑, *antiOx↑, *Inflam↓, *neuroP↑, *lipid-P↓, *toxicity↓, *NOX4↓, *SOD↑, *HNE↓, *IL6↓, *TNF-α↓, *IL1β↓, *Sepsis↓, *eff↑, *GABA↝, *Aβ↓, Glycolysis↓, AntiTum↑, p‑Akt↓, TumCCA↑, angioG↓, VEGFR2↓, NF-kB↓,
5952- Cela,    Celastrol attenuates Alzheimer’s disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress
- in-vivo, AD, NA
*memory↑, *Inflam↓, *ROS↓, *ER Stress↓, *neuroP↑, *Dose↝, *MDA↓, *SOD↑, *Catalase↑, *Aβ↓, BACE↓, LRP1↑, RAGE↓,
6017- CGA,    Therapeutic Potential of Chlorogenic Acid in Chemoresistance and Chemoprotection in Cancer Treatment
- Review, Var, NA
AntiCan↑, *chemoP↑, TNF-α↓, COX2↓, IL6↓, eff↑, PD-L1↓, *cognitive↓, *Aβ↓, *TAC↑, *SOD↑, *eff↑, *eff↑, ChemoSen↑, tumCV↓, Apoptosis↑, ERK↓, chemoP↑, *GPx↑, *GSTs↑, *GSH↑, *SOD↑, *Catalase↑, *ROS↓, *lipid-P↓, *MDA↓, *Casp3↓, *HO-1↓, cardioP↑, radioP↑,
6002- CGA,    Chlorogenic Acid: A Systematic Review on the Biological Functions, Mechanistic Actions, and Therapeutic Potentials
- Review, Var, NA - Review, Diabetic, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *Inflam↓, *antiOx↑, *cardioP↑, *NRF2↑, *AMPK↑, *SOD↑, *Catalase↑, *GSH↑, *GPx↑, *ROS↓, *TNF-α↓, *IL6↓, *NF-kB↓, *COX2↓, *glucose↓, *TRPC1↓, *Ca+2↓, *HO-1↑, *NF-kB↓, *PPARα↝, *Hif1a↓, *JNK↓, *BP↓, *AntiDiabetic↑, *hepatoP↑, *TLR4↓, *NRF2↑, *Casp↓, *neuroP↑, *Aβ↓, *LDH↓, *MDA↓, *memory↑, *AChE↓, *eff↑, EMT↝, N-cadherin↓, E-cadherin↑, TumCCA↑, ROS↑, p‑P53↑, HO-1↑, NRF2↑, ChemoSen↑, mtDam↑, Casp3↑, Casp9↑, PARP↑, Bax:Bcl2↑, TumCG↓, cycD1/CCND1↓, cMyc↓, CDK2↓, mitResp↓, Glycolysis↓, Hif1a↓, PCNA↓, p‑GSK‐3β↓, VEGF↓, PI3K↓, Akt↓, mTOR↓, OS↑,
6041- CGA,    Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study
- Trial, AD, NA
*Dose↝, *memory↑, *Risk↓, *cognitive↑, *Aβ↓, *antiOx↓, *motorD↑,
6043- CGA,  SeNPs,    Enhanced Effect of Combining Chlorogenic Acid on Selenium Nanoparticles in Inhibiting Amyloid β Aggregation and Reactive Oxygen Species Formation In Vitro
- in-vitro, AD, NA
*ROS↓, *Aβ↓, *BioAv↝, *BioAv↑, *Dose↝, *ROS↓, *H2O2↓, *toxicity↓,
6045- CGA,  SeNPs,    A Flower-like Brain Targeted Selenium Nanocluster Lowers the Chlorogenic Acid Dose for Ameliorating Cognitive Impairment in APP/PS1 Mice
- in-vivo, AD, NA
*neuroP↑, *BioAv↑, *GutMicro↑, *BBB↑, *Aβ↓, *glucose↝,
6023- CGA,    Pharmacological advances of the chlorogenic acids family: current insights and future research directions
- Review, AD, NA - Review, Park, NA - Review, IBD, NA
*Aβ↓, *neuroP↑, *cardioP↑, *GastroP↑, *RenoP↑, *hepatoP↑, *Obesity↓, *Bacteria↓, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *GutMicro↑, *IBI↑, *MCT1↓, *NF-kB↓, *DNMT1↓,
3701- Chol,    Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation
- in-vivo, AD, NA
*Ach↑, *Aβ↓, *memory↑, *APP↓, *eff↑, *neuroP↑, *Dose↑,
6135- CHr,    Chrysin as a Multifunctional Therapeutic Flavonoid: Emerging Insights in Pathogenesis Management: A Narrative Review
- Review, Var, NA - Review, AD, NA
Inflam↓, angioG↓, Apoptosis↑, TumAuto↑, TumCCA↑, BioAv↓, Half-Life↓, BioAv↓, *ROS↓, *hepatoP↑, *RenoP↑, TET1↑, MMP9↓, cMyc↓, Ki-67↓, CBR1↓, ROS↑, ChemoSen↑, Bax:Bcl2↑, PUMA↑, NOTCH1↑, *AntiDiabetic↑, *neuroP↑, *GABA↑, *DNAdam↓, *BDNF↑, *memory↑, *AGEs↓, *Aβ↓, *cardioP↑, *AntiArt↑, eff↑, eff↑, *eff↑, RadioS↑, eff↑, ChemoSen↑, eff↑,
6169- Cin,    Unlocking the Power of Cinnamon: A Detailed Review of Cinnamon Therapeutic Effects in Chronic Disease Management
- Review, Var, NA - Review, Diabetic, NA - Review, AD, NA - Review, IBD, NA
*neuroP↑, *AntiDiabetic↑, *tau↓, *Aβ↓, *antiOx↑, *Inflam↓, *ROS↓, *MDA↓, *GSH↓, *cardioP↑, *LDL↓, *HDL↑, *other↝, *TNF-α↓, *IL6↓, *MPO↓, *TLR4↓, *GutMicro↑, *lipid-P↓, *Wound Healing↑,
3889- Cin,    Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models
- in-vivo, AD, NA
*Aβ↓, *cognitive↑, *tau↓,
3888- Cin,    Cinnamon, a promising prospect towards Alzheimer's disease
- NA, AD, NA
*tau↓, *Aβ↓, *neuroP↑, *ROS↓, *Inflam↓, *cardioP↑, *antiOx↑, *cognitive↑, *BBB↑, *p‑GSK‐3β↑, *AChE↓,
3892- Cin,    Cinnamon from the selection of traditional applications to its novel effects on the inhibition of angiogenesis in cancer cells and prevention of Alzheimer's disease, and a series of functions such as antioxidant, anticholesterol, antidiabetes, antibacterial, antifungal, nematicidal, acaracidal, and repellent activities
- Review, AD, NA - Review, Var, NA
*antiOx↑, *Inflam↓, *cardioP↑, angioG↓, VEGF↓, *LDL↓, COX2↓, Hif1a↓, *Aβ↓, *tau↓, *toxicity↓,
3993- CoQ10,    Coenzyme Q10 Decreases Amyloid Pathology and Improves Behavior in a Transgenic Mouse Model of Alzheimer’s Disease
- Review, Park, NA - Review, AD, NA
*neuroP↑, *Aβ↓, *ROS↓, *cognitive↑, *antiOx↑,
3624- Cro,    Crocus Sativus L. (Saffron) in Alzheimer's Disease Treatment: Bioactive Effects on Cognitive Impairment
- Review, AD, NA
*AChE↓, *memory↑, *cognitive↑, *MDA↑, *Thiols↑, *GPx↑, *antiOx↑, *ROS↓, *Casp3↓, *neuroP↑, *SOD↑, *Ach↑, *ChAT↑, *BBB↑, *Aβ↓, *tau↓, *cognitive↑, *Inflam↓,
3625- Cro,    Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and placebo-controlled trial
- Trial, AD, NA
*Aβ↓, *cognitive↑,
3627- Cro,    The effects of Crocus sativus (saffron) and its constituents on nervous system: A review
- Review, AD, NA - Review, Stroke, NA
*other↑, *monoA↑, *Aβ↓, *AChE↓, *cognitive↑, *neuroP↑, *lipid-P↓, *SOD↑, *ROS↓, *GPx↑, *MDA↓, *memory↑, *antiOx↑, *Inflam↓, *other↓, *ER Stress↓,
3628- Cro,  VitE,  CUR,    Vitamin E, Turmeric and Saffron in Treatment of Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *ROS↓, *lipid-P↓, *Aβ↓, *AChE↓, *cognitive↑, *Inflam↓,
3631- Cro,    Investigation of the neuroprotective effects of crocin via antioxidant activities in HT22 cells and in mice with Alzheimer's disease
- in-vitro, AD, HT22 - in-vivo, AD, NA
*ROS↓, *Ca+2↓, *BAX↓, *BAD↓, *Casp3↓, *cognitive↑, *memory↑, *Aβ↓, *GPx↑, *SOD↑, *ChAT↑, *Ach↑, *AChE↓, *ROS↓, *p‑Akt↑, *p‑mTOR↑, *neuroP↑,
6207- CUR,    Enhancing the Bioavailability and Bioactivity of Curcumin for Disease Prevention and Treatment
- Review, Var, NA - Review, AD, NA
*AntiCan↑, *Obesity↓, *Inflam↓, *lipid-P↓, *BioAv↓, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *mt-SOD↑, *MDA↓, *BBB↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroG↑, *memory↑, cardioP↑,
6208- CUR,    Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial
- Trial, Nor, NA
*memory↑, *Aβ↓, *tau↓,
6050- CUR,  SeNPs,    Efficacy of curcumin-selenium nanoemulsion in alleviating oxidative damage induced by aluminum chloride in a rat model of Alzheimer's disease
- in-vivo, AD, NA
*cognitive↑, *AChE↓, *Aβ↓, *P53↓, *tau↓, *NRF2↓, *TNF-α↓, *NO↑, *Catalase↑, *antiOx↑, *Inflam↓,
2816- CUR,    NEUROPROTECTIVE EFFECTS OF CURCUMIN
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *antiOx↑, *BioAv↓, *AP-1↓, *NF-kB↓, *HATs↓, *HDAC↑, Dose↑, *ROS↓, *cognitive↑, *Aβ↓,
3748- CUR,  RES,  Hup,  Riv,  Gala  Natural acetylcholinesterase inhibitors: A multi-targeted therapeutic potential in Alzheimer's disease
- Review, AD, NA
*AChE↓, *Inflam↓, *Aβ↓, *cognitive↑, *ROS↓,
3860- CUR,    Curcumin Ameliorates Memory Decline via Inhibiting BACE1 Expression and β-Amyloid Pathology in 5×FAD Transgenic Mice
- in-vivo, AD, NA
*Aβ↓, *BACE↓, *memory↑,
3793- CUR,    Curcumin Downregulates GSK3 and Cdk5 in Scopolamine-Induced Alzheimer’s Disease Rats Abrogating Aβ40/42 and Tau Hyperphosphorylation
- in-vivo, AD, NA
*Aβ↓, *p‑tau↓, *GSK‐3β↓, *CDK5↓, *memory↑,
3795- CUR,    Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence
- Review, AD, NA
*antiOx↑, *Inflam↓, *AntiAge↑, *AMPK↑, *SIRT1↑, *NF-kB↓, *mTOR↓, *NLRP3↓, *NADPH↓, *ROS↓, *COX2↓, *MCP1↓, *IL1β↓, *IL17↓, *IL23↓, *TNF-α↓, *MPO↓, *IL10↑, *lipid-P↓, *SOD↑, *Aβ↓, *p‑tau↓, *GSK‐3β↓, *CDK5↓, *TXNIP↓, *NRF2↑, *NQO1↑, *HO-1↑, *OS↑, *memory↑, *BDNF↑, *neuroP↑, *BACE↓, *AChE↓, *LDL↓,
3584- CUR,    Curcumin in Health and Diseases: Alzheimer’s Disease and Curcumin Analogues, Derivatives, and Hybrids
*AChE↓, *Inflam↓, *antiOx↑, *Aβ↓, *ROS↓,
3576- CUR,    Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer's Disease
- Review, AD, NA
*Inflam↓, *antiOx↑, *memory↑, *Aβ↓, *BBB↑, *cognitive↑, *tau↓, *LDL↓, *AChE↓, *IL1β↓, *IronCh↑, *neuroP↑, *BioAv↝, *PI3K↑, *Akt↑, *NRF2↑, *HO-1↑, *Ferritin↑, *HO-2↓, *ROS↓, *Ach↑, *GSH↑, *Bcl-2↑, *ChAT↑,
3575- CUR,    The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
- in-vivo, AD, NA
*antiOx↑, *ROS↓, *IL1β↓, *Aβ↓, *Inflam↓, *toxicity↓,
3574- CUR,    The effect of curcumin (turmeric) on Alzheimer's disease: An overview
- Review, AD, NA
*antiOx↑, *Inflam↓, *lipid-P↓, *cognitive↑, *memory↑, *Aβ↓, *COX2↓, *ROS↓, *AP-1↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *SOD↑, *GSH↑, *HO-1↑, *IronCh↑, *BioAv↓, *Half-Life↝, *Dose↝, *BBB↑, *BioAv↑, *toxicity∅, *eff↑,
6259- Cyste,    Therapeutic Applications of Cysteamine and Cystamine in Neurodegenerative and Neuropsychiatric Diseases
- Review, AD, NA - Review, Park, NA
*ROS↓, *neuroP↑, *BDNF↑, *NRF2↑, *BBB↑, *HSPs↑, *GSH↑, *TG2/TGase↓, Aβ↓,
3707- dietSTF,    Intermittent fasting protects against the deterioration of cognitive function, energy metabolism and dyslipidemia in Alzheimer’s disease-induced estrogen deficient rats
- in-vivo, AD, NA
*memory↑, *Aβ↓, *AST↓, *ALAT↓,
3709- dietSTF,    Intermittent Fasting Protects against Alzheimer’s Disease Possible through Restoring Aquaporin-4 Polarity
- in-vitro, AD, NA
*cognitive↑, *Aβ↓, *AQPs↓, *HDAC3↓,
6288- DL,    From Citrus to Clinic: Limonene’s Journey Through Preclinical Research, Clinical Trials, and Formulation Innovations
- Review, Var, NA - Review, AD, NA
other↑, DDS↑, *antiOx↑, *Inflam↓, *AntiDiabetic↑, *neuroP↑, *Imm↑, *Wound Healing↑, *other↑, *BioAv↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *DNAdam↓, *AntiDiabetic↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↓, *AChE↓, *BChE↓, *Aβ↓, *ROS↓, *toxicity?,
6281- DL,    Applications of Limonene in Neoplasms and Non-Neoplastic Diseases
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
*antiOx↑, AntiTum↑, *AntiDiabetic↑, *neuroP↑, *GastroP↑, *ROS↓, *toxicity↓, *BioAv↑, ChemoSen↑, BAX↑, P53↓, Bcl-2↓, iNOS↓, COX2↓, eff↑, ROS↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, TumCMig↓, *lipid-P↓, *GSH↑, *SOD↑, *GPx↑, *hepatoP↑, *glucose↓, *AGEs↓, *Obesity↓, *Aβ↓, *AChE↓,
6049- EGCG,  SeNPs,    Epigallocatechin-3-gallate (EGCG)-stabilized selenium nanoparticles coated with Tet-1 peptide to reduce amyloid-β aggregation and cytotoxicity
- Study, AD, PC12
*Aβ↓, *Dose↝, *BioAv↑, *ROS↓,
3232- EGCG,    (−)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer׳s disease model mice by upregulating neprilysin expression
- in-vivo, AD, NA
HDAC1↓, *HDAC1↓, *Aβ↓, *cognitive↑,
3237- EGCG,    (-)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer's disease model mice by upregulating neprilysin expression
- in-vivo, AD, NA
*HDAC↓, *Aβ↓, cognitive↑,
3591- EGCG,    Epigallocatechin-3-Gallate Provides Protection Against Alzheimer's Disease-Induced Learning and Memory Impairments in Rats
- in-vivo, AD, NA
*p‑tau↓, *BACE↓, *Aβ↓, *Ach↑, *AChE↓, *antiOx↑, *memory↑, *hepatoP↑, *ROS↓, *GPx↑, *SOD↑,
3593- EGCG,    Epigallocatechin Gallate (EGCG)
- Review, AD, NA
AntiTum↑, *Inflam↓, *neuroP↑, *Aβ↓, *BioAv↝, cognitive↑,
3830- EMD,    Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease
- Review, AD, NA
*neuroP↑, *Aβ↓, *p‑tau↓, *BACE↓,
6378- Eug,    Effects of Eugenol on the Central Nervous System: Its Possible Application to Treatment of Alzheimer's Disease, Depression, and Parkinson's Disease
- Review, AD, NA
*other↑, *Aβ↓, *BDNF↑, *MAOA↑, *toxicity↓, *Ca+2↓, *antiOx↑, *ROS↓, *lipid-P↓, *neuroP↑, *PGE2↓, *COX2↓, *5LO↓,
6377- Eug,    Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review
- Review, Var, NA - Review, AD, NA
*Inflam↓, *Bacteria↓, ChemoSen↑, *selectivity↑, ROS⇅, TumCG↓, MMP↓, antiOx⇅, *antiOx↑, *BBB↑, *neuroP↑, *BDNF↑, *Aβ↓, *Ca+2↓, *5LO↓, *MAOA↓, other↑,
4068- FA,    Hyperhomocysteinemia in Alzheimer's disease: the hen and the egg?
- in-vivo, AD, NA
*homoC↓, *Aβ↓,
4070- FA,    Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial
- Trial, AD, NA
*cognitive↑, *Aβ↓, *TNF-α↓, *Inflam↓,
4071- FA,    Folate and Alzheimer: when time matters
- Review, AD, NA
*cognitive↑, *ROS↓, *Ca+2↓, *p‑tau↓, *Aβ↓,
3783- FA,    Design, Synthesis, and Biological Evaluation of Ferulic Acid-Piperazine Derivatives Targeting Pathological Hallmarks of Alzheimer’s Disease
- NA, AD, NA
*ROS↓, *IronCh↑, *NLRP3↓, *Aβ↓, *AChE↓, *BChE↓, *antiOx↑, *BBB↑, *MMP↑, *memory↑, *SOD↑, *Catalase↑,

Showing Research Papers: 51 to 100 of 264
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 264

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

CBR1↓, 1,  

Redox & Oxidative Stress ⓘ

antiOx⇅, 1,   HO-1↑, 1,   NRF2↑, 1,   ROS↑, 3,   ROS⇅, 1,  

Mitochondria & Bioenergetics ⓘ

mitResp↓, 1,   MMP↓, 1,   mtDam↑, 1,  

Core Metabolism/Glycolysis ⓘ

cMyc↓, 2,   Glycolysis↓, 2,  

Cell Death ⓘ

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↑, 2,   BAX↑, 2,   Bax:Bcl2↑, 2,   Bcl-2↓, 2,   Casp3↑, 2,   Casp9↑, 2,   iNOS↓, 1,   PUMA↑, 1,  

Transcription & Epigenetics ⓘ

other↑, 2,   tumCV↓, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

DNA Damage & Repair ⓘ

P53↓, 1,   p‑P53↑, 1,   PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 2,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State ⓘ

EMT↝, 1,   ERK↓, 1,   p‑GSK‐3β↓, 1,   HDAC1↓, 1,   mTOR↓, 1,   NOTCH1↑, 1,   PI3K↓, 1,   TumCG↓, 2,  

Migration ⓘ

E-cadherin↑, 1,   Ki-67↓, 1,   LRP1↑, 1,   MMP9↓, 1,   N-cadherin↓, 1,   RAGE↓, 1,   TET1↑, 1,   TumCMig↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 3,   Hif1a↓, 2,   VEGF↓, 2,   VEGFR2↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 3,   IL6↓, 1,   Inflam↓, 1,   NF-kB↓, 1,   PD-L1↓, 1,   TNF-α↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,   BACE↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   ChemoSen↑, 6,   DDS↑, 1,   Dose↑, 1,   eff↑, 6,   Half-Life↓, 1,   RadioS↑, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,   Ki-67↓, 1,   PD-L1↓, 1,   RAGE↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   AntiTum↑, 3,   cardioP↑, 2,   chemoP↑, 1,   cognitive↑, 2,   OS↑, 1,   radioP↑, 1,  
Total Targets: 78

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

AntiArt↑, 1,  

Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 23,   Catalase↑, 6,   GPx↑, 7,   GSH↓, 1,   GSH↑, 7,   GSTs↑, 1,   H2O2↓, 1,   HDL↑, 1,   HNE↓, 1,   HO-1↓, 1,   HO-1↑, 4,   HO-2↓, 1,   lipid-P↓, 10,   MDA↓, 6,   MDA↑, 1,   MPO↓, 2,   NOX4↓, 1,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 5,   ROS↓, 34,   SOD↑, 14,   mt-SOD↑, 1,   TAC↑, 1,   Thiols↑, 1,  

Metal & Cofactor Biology ⓘ

Ferritin↑, 1,   IronCh↑, 4,  

Mitochondria & Bioenergetics ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   AMPK↑, 2,   glucose↓, 2,   glucose↝, 1,   homoC↓, 1,   LDH↓, 1,   LDL↓, 4,   NADPH↓, 1,   PPARα↝, 1,   SIRT1↑, 1,  

Cell Death ⓘ

Akt↑, 1,   p‑Akt↑, 1,   BAD↓, 1,   BAX↓, 1,   Bcl-2↑, 1,   Casp↓, 1,   Casp3↓, 3,   JNK↓, 1,   MCT1↓, 1,  

Transcription & Epigenetics ⓘ

Ach↑, 5,   HATs↓, 1,   other↓, 1,   other↑, 3,   other↝, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 2,   HSPs↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 2,   DNMT1↓, 1,   P53↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

GSK‐3β↓, 3,   p‑GSK‐3β↑, 1,   HDAC↓, 1,   HDAC↑, 1,   HDAC1↓, 1,   HDAC3↓, 1,   mTOR↓, 1,   p‑mTOR↑, 1,   neuroG↑, 1,   PI3K↑, 1,  

Migration ⓘ

5LO↓, 2,   AP-1↓, 2,   APP↓, 1,   Ca+2↓, 5,   CDK5↓, 2,   TG2/TGase↓, 1,   TRPC1↓, 1,   TXNIP↓, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↓, 1,   NO↓, 1,   NO↑, 1,  

Barriers & Transport ⓘ

AQPs↓, 1,   BBB↓, 1,   BBB↑, 8,   GastroP↑, 2,   IBI↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 4,   IL10↑, 1,   IL17↓, 1,   IL1β↓, 5,   IL23↓, 1,   IL6↓, 3,   Imm↑, 1,   Inflam↓, 23,   MCP1↓, 1,   NF-kB↓, 6,   PGE2↓, 1,   TLR4↓, 2,   TNF-α↓, 7,  

Synaptic & Neurotransmission ⓘ

AChE↓, 15,   BChE↓, 2,   BDNF↑, 5,   ChAT↑, 3,   GABA↑, 1,   GABA↝, 1,   MAOA↓, 1,   MAOA↑, 1,   monoA↑, 1,   tau↓, 9,   p‑tau↓, 5,  

Protein Aggregation ⓘ

AGEs↓, 2,   Aβ↓, 49,   BACE↓, 4,   NLRP3↓, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 3,   BioAv↑, 14,   BioAv↝, 3,   Dose↑, 1,   Dose↝, 5,   eff↑, 7,   Half-Life↝, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   AST↓, 1,   BP↓, 1,   Ferritin↑, 1,   GutMicro↑, 3,   IL6↓, 3,   LDH↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 2,   AntiCan↑, 1,   AntiDiabetic↑, 6,   cardioP↑, 6,   chemoP↑, 1,   cognitive↓, 1,   cognitive↑, 19,   hepatoP↑, 5,   memory↑, 18,   motorD↑, 1,   neuroP↑, 25,   Obesity↓, 3,   OS↑, 1,   RenoP↑, 2,   Risk↓, 1,   toxicity?, 1,   toxicity↓, 6,   toxicity∅, 1,   Wound Healing↑, 2,  

Infection & Microbiome ⓘ

Bacteria↓, 2,   Sepsis↓, 1,  
Total Targets: 149

Scientific Paper Hit Count for: Aβ, Aβ aggregation
19 Selenium NanoParticles
17 Curcumin
14 Resveratrol
14 Urolithin
12 Magnetic Fields
11 Ferulic acid
8 Berberine
8 EGCG (Epigallocatechin Gallate)
8 Chlorogenic acid
8 Thymoquinone
7 Alpha-Lipoic-Acid
7 Quercetin
7 Rosmarinic acid
6 EMF
5 Ashwagandha(Withaferin A)
5 Carnosine
5 Crocetin
5 Hydrogen Gas
5 Magnetic Field Rotating
5 Mushroom Lion’s Mane
5 Rutin
5 Sulforaphane (mainly Broccoli)
4 Apigenin (mainly Parsley)
4 Capsaicin
4 Cinnamon
4 Folic Acid, Vit B9
4 Ginseng
4 Silymarin (Milk Thistle) silibinin
4 Vitamin B1/Thiamine
3 beta-carotene(VitA)
3 Honokiol
3 Luteolin
3 Radio Frequency
3 Vitamin B3,Niacin
3 Vitamin B5,Pantothenic Acid
3 Vitamin K2
2 Aromatherapy
2 Huperzine A/Huperzia serrata
2 Bacopa monnieri
2 borneol
2 Boron
2 Boswellia (frankincense)
2 α-Bisabolol / Chamomile oil
2 Vitamin E
2 diet Short Term Fasting
2 D-limonene
2 Eugenol
2 Ginkgo biloba
2 MCToil
2 Moringa oleifera
2 chitosan
2 Taurine
2 Vitamin D3
1 1,8-Cineole
1 Anthocyanins
1 Astaxanthin
1 Caffeic acid
1 Carnosic acid
1 Celastrol
1 Choline
1 Chrysin
1 Coenzyme Q10
1 Rivastigmine
1 Galantamine
1 Cysteamine
1 Emodin
1 Phosphatidylserine
1 Fisetin
1 Flickering Light Stimulation
1 Exercise
1 Shilajit/Fulvic Acid
1 Iron
1 hydrogen sulfide
1 Lutein
1 Zeaxanthin
1 Lycopene
1 Methylsulfonylmethane
1 Nimbolide
1 Piperine
1 Piperlongumine
1 Salvia officinalis
1 S-adenosyl-L-methionine
1 Carvacrol
1 Sesame seeds and Oil
1 Silicic Acid
1 Spermidine
1 Ursolic acid
1 Vitamin A, Retinoic Acid
1 Vitamin B12
1 Vitamin B2,Riboflavin
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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