Ach Cancer Research Results

Ach, Acetylcholine: Click to Expand ⟱
Source:
Type:
Acetylcholine (ACh) 
↓ Acetylcholine (ACh) levels in AD patients


Scientific Papers found: Click to Expand⟱
4324- VitB5,    Substantively Lowered Levels of Pantothenic Acid (Vitamin B5) in Several Regions of the Human Brain in Parkinson’s Disease Dementia
- Study, AD, NA - Study, Park, NA
*Risk↓, *other↝, *other↝, *Ach↑, *Aβ↑, *other?,
4323- VitB5,    Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer's disease
- Study, AD, NA
*Risk↓, *Acetyl-CoA↑, *Ach↑, *neuroP↑,
4188- VitK2,    Vitamin K2 protects against aluminium chloride-mediated neurodegeneration
- in-vivo, AD, NA
*BDNF↑, *Aβ↓, *cognitive↑, *Ach↑, *Inflam↓,

Showing Research Papers: 51 to 53 of 53
Prev Page 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 53

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

OXPHOS↓, 1,   PDH↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 2,   FDG↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   EGFR↓, 1,   mTOR↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

TumCI↓, 1,   TumCMig↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

EGR4↓, 1,   VEGF↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

Ach↓, 1,   AChE↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 1,   Half-Life↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,  
Total Targets: 22

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

3-NT↓, 1,   4-HNE↓, 1,   antiOx↑, 18,   Catalase↑, 6,   GPx↑, 9,   GSH↑, 11,   H2O2↓, 1,   HO-1↑, 4,   HO-2↓, 1,   lipid-P↓, 9,   MDA↓, 5,   MDA↑, 1,   Nrf1↑, 1,   NRF2↑, 10,   ROS↓, 30,   ROS↑, 1,   SOD↑, 13,   SOD2↑, 1,   TAC↑, 3,   TBARS↓, 1,   Thiols↑, 2,   VitC↑, 1,   VitE↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↑, 1,   IronCh↑, 6,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

mtDam↓, 1,   PDH↑, 1,   PGC-1α↓, 1,   PGC-1α↑, 3,   SIRT3↑, 1,   TFAM↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 2,   Acetyl-CoA↑, 4,   ALAT↓, 2,   ATP↑, 3,   cAMP↑, 1,   DHA↑, 1,   GlucoseCon↑, 5,   GSK‐3β↓, 3,   LDL↓, 2,   PDKs↓, 1,   SIRT1↑, 4,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 3,   BAD↓, 1,   BAX↓, 3,   Bcl-2↑, 4,   Casp3↓, 5,   cl‑Casp3↓, 1,   Casp9↓, 1,   iNOS↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↑, 4,   p‑Akt↓, 2,   p‑Akt↑, 1,   CREB↑, 1,   p‑CREB↑, 2,   MAPK↓, 2,   mTOR↓, 1,   mTOR↑, 1,   p‑mTOR↑, 1,   PI3K↑, 4,   PTEN↓, 1,   PTP1B↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 1,   other?, 4,   other↓, 2,   other↝, 10,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,   GRP78/BiP↓, 1,   HSP90↓, 1,   HSPs↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

Ki-67↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

cFos↑, 1,   Choline↑, 1,   EP2↑, 1,   Ki-67↓, 1,  

Migration(tgid=13) ⓘ

ATPase↑, 1,   Ca+2?, 1,   Ca+2↓, 4,   MMP-10↓, 1,   MMP1↓, 1,   MMP9↓, 1,   TGF-β1↑, 1,   TIMP1↑, 1,   TIMP2↑, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↑, 1,   NO↓, 1,   VCAM-1↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 9,   BBB↝, 1,   GLUT3↑, 1,   GLUT4↑, 1,   MMP↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2?, 1,   COX2/PTGS2↓, 4,   IL1↓, 1,   IL10↑, 1,   IL1β↓, 11,   IL2↓, 1,   IL6↓, 8,   INF-γ↓, 1,   Inflam↓, 25,   NeuroI↓, 3,   NF-kB↓, 7,   NLRP3↓, 1,   PGE2↓, 2,   RAGE↓, 1,   TLR1↓, 1,   TLR4↓, 1,   TNF-α↓, 13,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 6,   Ach?, 1,   Ach↑, 51,   AChE↓, 24,   BChE↓, 3,   BDNF↑, 12,   ChAT↑, 13,   GABA↑, 2,   MAOA↓, 2,   MAOA↝, 1,   NGF↑, 2,   PSD95↑, 1,   RELN↑, 1,   SNAP25↑, 1,   TrkB↑, 2,   TrkB↝, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   APP↓, 4,   Aβ↓, 22,   Aβ↑, 1,   Aβ42↓, 3,   BACE/β-secretase↓, 2,   PSEN1/PS1↓, 1,   tau↓, 6,   p‑tau↓, 7,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

PPARγ↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 4,   BioAv↝, 4,   BioEnh↑, 1,   Dose↑, 2,   Dose↝, 5,   eff↓, 1,   eff↑, 6,   Half-Life↓, 3,   Synergy↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALB↑, 1,   AST↓, 2,   BP↓, 2,   Ferritin↑, 1,   Hcy/homoC↓, 1,   HemoG↑, 1,   IL6↓, 8,   LDH↓, 1,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 1,   cardioP↑, 1,   cognitive↑, 34,   hepatoP↑, 3,   Learn↑, 1,   memory↑, 29,   Mood↑, 1,   motorD↑, 1,   neuroP↑, 30,   Obesity↓, 1,   Pain↓, 1,   Risk↓, 3,   Sleep↑, 4,   Stress↓, 1,   Stroke↓, 1,   toxicity↓, 2,   Weight↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,  
Total Targets: 178

Scientific Paper Hit Count for: Ach, Acetylcholine
7 Alpha-Lipoic-Acid
4 Choline
4 Vitamin B5,Pantothenic Acid
3 Crocetin
3 Curcumin
3 Phosphatidylserine
3 Thymoquinone
2 Apigenin (mainly Parsley)
2 Gamma-aminobutyric acid
2 Lactoferrin/Talactoferrin
2 Moringa oleifera
1 5-Hydroxytryptophan
1 Aromatherapy
1 Ashwagandha(Withaferin A)
1 Bacopa monnieri
1 Boswellia (frankincense)
1 Citicoline, CDP-Choline
1 Galantamine
1 EGCG (Epigallocatechin Gallate)
1 Ferulic acid
1 Folic Acid, Vit B9
1 Honokiol
1 Huperzine A/Huperzia serrata
1 isoquercitrin
1 L-Theanine
1 Licochalcone A
1 Lycopene
1 Magnetic Field Rotating
1 Magnetic Fields
1 Melatonin
1 alpha Linolenic acid
1 Quercetin
1 Sinapic acid
1 Mung Bean Sprouts
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1347  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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