BACE Cancer Research Results

BACE, β-site APP-cleaving enzyme: Click to Expand ⟱
Source:
Type:
BACE stands for β-site APP-cleaving enzyme, also known as β-secretase. It plays a central role in the pathogenesis of Alzheimer’s disease by initiating the production of amyloid-β (Aβ) peptides, the primary components of amyloid plaques found in the brains of individuals with AD.
-inhibiting BACE1 reduces Aβ production.
Scientific Papers found: Click to Expand⟱
4033- VitB3,    Can nicotinamide riboside protect against cognitive impairment?
- in-vivo, AD, NA
*memory↑, *DNAdam↓, *Inflam↓, *Apoptosis↓, *cognitive↑, *BACE↓, *Aβ↓, *BBB↑, *GutMicro↑, *eff↑,
3921- VitD3,  RES,    Vitamin D Combined with Resveratrol Prevents Cognitive Decline in SAMP8 Mice
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *BACE↓, *p‑tau↓, *p‑CREB↑, *p‑NF-kB↓, *neuroP↑,

Showing Research Papers: 51 to 52 of 52
Prev Page 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 52

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Core Metabolism/Glycolysis ⓘ

p‑CREB↑, 1,  

Cell Death ⓘ

Apoptosis↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,   p‑NF-kB↓, 1,  

Synaptic & Neurotransmission ⓘ

p‑tau↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 2,   BACE↓, 2,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  

Clinical Biomarkers ⓘ

GutMicro↑, 1,  

Functional Outcomes ⓘ

cognitive↑, 2,   memory↑, 1,   neuroP↑, 1,  
Total Targets: 14

Scientific Paper Hit Count for: BACE, β-site APP-cleaving enzyme
3 Berberine
3 Curcumin
3 Huperzine A/Huperzia serrata
3 Resveratrol
3 Urolithin
2 EGCG (Epigallocatechin Gallate)
2 Biochanin A
2 Ginseng
2 Hydrogen Gas
2 Moringa oleifera
2 Quercetin
2 Sulforaphane (mainly Broccoli)
2 Vitamin B3,Niacin
1 1,8-Cineole
1 Anthocyanins
1 Apigenin (mainly Parsley)
1 Aromatherapy
1 Ashwagandha(Withaferin A)
1 Astaxanthin
1 beta-carotene(VitA)
1 Brucea javanica
1 Bacopa monnieri
1 borneol
1 α-Bisabolol / Chamomile oil
1 Celastrol
1 Ellagic acid
1 Emodin
1 Ferulic acid
1 Luteolin
1 Lycopene
1 Magnetic Fields
1 Mushroom Lion’s Mane
1 EMF
1 Thymoquinone
1 Vitamin A, Retinoic Acid
1 Vitamin B1/Thiamine
1 Vitamin B12
1 Folic Acid, Vit B9
1 Vitamin D3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1349  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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