BDNF Cancer Research Results

BDNF, brain-derived neurotrophic factor: Click to Expand ⟱
Source:
Type:
Brain-Derived Neurotrophic Factor (BDNF) is a key neurotrophin (a type of growth factor) involved in brain health, and its role in Alzheimer’s Disease (AD) has been extensively studied.
-AD patients often have lower BDNF levels in key brain regions, such as the hippocampus and cortex.
-This reduction correlates with cognitive decline and brain atrophy.
-BDNF normally protects neurons from Aβ toxicity
-Exercise and cognitive training have been shown to boost BDNF levels and may slow cognitive decline.
- natural compounds (like curcumin or flavonoids) may also upregulate BDNF.
Scientific Papers found: Click to Expand⟱
3795- CUR,    Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence
- Review, AD, NA
*antiOx↑, *Inflam↓, *AntiAge↑, *AMPK↑, *SIRT1↑, *NF-kB↓, *mTOR↓, *NLRP3↓, *NADPH↓, *ROS↓, *COX2↓, *MCP1/CCL2↓, *IL1β↓, *IL17↓, *IL23↓, *TNF-α↓, *MPO↓, *IL10↑, *lipid-P↓, *SOD↑, *Aβ↓, *p‑tau↓, *GSK‐3β↓, *CDK5↓, *TXNIP↓, *NRF2↑, *NQO1↑, *HO-1↑, *OS↑, *memory↑, *BDNF↑, *neuroP↑, *BACE↓, *AChE↓, *LDL↓,
3797- CUR,    Curcumin reverses cognitive deficits through promoting neurogenesis and synapse plasticity via the upregulation of PSD95 and BDNF in mice
- in-vitro, NA, NA
*cognitive↑, *BDNF↑, *PSD95↑, *memory↑,
4333- Cyste,    Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription
- vitro+vivo, AD, NA
*NRF2↑, *ARE↑, *neuroP↑, *BDNF↑, *GSH↑,
4331- Cyste,    Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase
- in-vivo, HD, NA - NA, AD, NA
*BDNF↑, *neuroP↑, *TG2/TGase↓,
6259- Cyste,    Therapeutic Applications of Cysteamine and Cystamine in Neurodegenerative and Neuropsychiatric Diseases
- Review, AD, NA - Review, Park, NA
*ROS↓, *neuroP↑, *BDNF↑, *NRF2↑, *BBB↑, *HSPs↑, *GSH↑, *TG2/TGase↓, Aβ↓,
4178- DHA,    The salutary effects of DHA dietary supplementation on cognition, neuroplasticity, and membrane homeostasis after brain trauma
- in-vivo, NA, NA
*BDNF↑, *CREB↑, *cognitive↑, *SOD↑,
4177- DHA,    Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats
- in-vivo, NA, NA
*BDNF↑, *CREB↑, *ROS↓, *cognitive↑,
4256- dietMed,    Association between Mediterranean dietary pattern with sleep duration, sleep quality and brain derived neurotrophic factor (BDNF) in Iranian adults
- Study, Nor, NA
*Sleep↑, *BDNF↑,
4180- dietSTF,    Brain-derived neurotrophic factor, but not body weight, correlated with a reduction in depression scale scores in men with metabolic syndrome: a prospective weight-reduction study
- Human, Obesity, NA
*BDNF↑,
4159- dietSTF,  2DG,  CRMs,    Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms
- Review, AD, NA
*BDNF↑, *HSPs↑, *eff↑,
4252- EA,    Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression
- in-vivo, NA, NA
*BDNF↑, *p‑AKT1↑,
4253- EA,    The effects of Ellagic acid supplementation on neurotrophic, inflammation, and oxidative stress factors, and indoleamine 2, 3-dioxygenase gene expression in multiple sclerosis patients with mild to moderate depressive symptoms: A randomized, triple-blind, placebo-controlled trial
- Human, MS, NA - NA, IBD, NA
*Mood↑, *BDNF↑, *5HT↑, *antiOx↑, *Inflam↓, *AntiCan↑, *QoL↑, *neuroP↑, *cognitive↑, *memory↑, *Dose↝,
4254- EA,    Chronic administration of ellagic acid improved the cognition in middle-aged overweight men
- Human, Obesity, NA
*LDL↓, *HDL↑, *BDNF↑, *cognitive↑,
4255- EA,    Effects of nutritional interventions on BDNF concentrations in humans: a systematic review
- Review, NA, NA
*BDNF↑,
4152- EGCG,    Green tea catechins potentiate the neuritogenic action of brain-derived neurotrophic factor: role of 67-kDa laminin receptor and hydrogen peroxide
- in-vitro, AD, NA
*BDNF↑,
6819- EMD,    Recent advances in the therapeutic potential of emodin for human health
- Review, Nor, NA
AntiCan↑, *AntiDiabetic↑, *neuroP↑, *Inflam↓, *antiOx↑, *BioAv↓, *BioAv↑, *SOD↑, *GPx↑, *GSH↑, *NRF2↑, *ROS↓, *lipid-P↓, *Cyt‑c↓, *BAX↓, *Bcl-2↓, *iNOS↓, *NO↓, *IL6↓, *IL10↓, *IL17↓, *IFN-γ↓, *NF-kB↓, *LC3II↓, *Akt↓, *Beclin-1↓, *AMPK↓, *TNF-α↓, *PGE2↓, *Apoptosis↓, *Casp3↓, *Casp9↓, *P53↓, *P21↓, *NAD↓, *ATP↓, *CHOP/DDIT3↓, *GADD34↓, *ATF4↓, tumCV↓, Apoptosis↑, TumCG↓, TumCI↓, TumMeta↓, CSCs↓, NOTCH1↓, STAT3↓, eff↑, miR-34a↓, *neuroP↑, *BDNF↓, *hepatoP↑, *ALAT↓, *AST↓, TG/TAG↓, ROS↑, Slug↓, EMT↓, Glycolysis↓, ChemoSen↑, P-gp↓, Ki-67↓, PCNA↓, ER Stress↑, TRIB3↑, NF-kB↑, TumMeta↑, *Imm↓, *toxicity↝,
6378- Eug,    Effects of Eugenol on the Central Nervous System: Its Possible Application to Treatment of Alzheimer's Disease, Depression, and Parkinson's Disease
- Review, AD, NA
*other↑, *Aβ↓, *BDNF↑, *MAOA↑, *toxicity↓, *Ca+2↓, *antiOx↑, *ROS↓, *lipid-P↓, *neuroP↑, *PGE2↓, *COX2↓, *5LO↓,
6377- Eug,    Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review
- Review, Var, NA - Review, AD, NA
*Inflam↓, *Bacteria↓, ChemoSen↑, *selectivity↑, ROS⇅, TumCG↓, MMP↓, antiOx⇅, *antiOx↑, *BBB↑, *neuroP↑, *BDNF↑, *Aβ↓, *Ca+2↓, *5LO↓, *MAOA↓, other↑,
4140- Ex,    Experimental and clinical evidence of physical exercise on BDNF and cognitive function: A comprehensive review from molecular basis to therapy
- Review, AD, NA
*BDNF↑, *cognitive↑,
4174- Ex,    Exercise-Mediated Neurogenesis in the Hippocampus via BDNF
- Review, NA, NA
*neuroP↑, *cognitive↑, *memory↑, *BDNF↑, *neuroG↑,
4155- Ex,    Prior regular exercise reverses the decreased effects of sleep deprivation on brain-derived neurotrophic factor levels in the hippocampus of ovariectomized female rats
- in-vivo, AD, NA
*BDNF↑,
4139- Ex,    Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases
- Review, AD, NA
*BDNF↑, *eff↑, *eff↑, *cognitive↑, *memory↑, *BrainVol↑, *TrkB↑, *GABA↑,
4141- Ex,    Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis
- Review, AD, NA
*BDNF↑, *other↑, *eff↑,
4142- Ex,    Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease
- Review, AD, NA
*BDNF↑, *cognitive↑,
4143- Ex,    Brain-Derived Neurotrophic Factor: A Connecting Link Between Nutrition, Lifestyle, and Alzheimer’s Disease
- Review, AD, NA
*BDNF↑, *eff↑, *other↓, *eff↑,
4144- Ex,    Exploring the impact of exercise-induced BDNF on neuroplasticity in neurodegenerative and neuropsychiatric conditions
- Review, AD, NA
*BDNF↑, *memory↑, *neuroP↑, *cognitive↑,
4145- Ex,    Effects of different physical activities on brain-derived neurotrophic factor: A systematic review and bayesian network meta-analysis
- Review, AD, NA
*BDNF↑, *eff↑,
3714- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK↓, *p38↓, *JNK↓, *IL6↓, *IL8↓, *hepatoP↑, *RenoP↑, *Catalase↑, *PPARγ↑, *ROS↓, *Fenton↓, *IronCh↑, *SOD↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ARE↑, *Bil↑, *radioP↑, *GCLC↑, *GCLM↑, *NQO1↑, *Half-Life↝, *GutMicro↑, *Aβ↓, *BDNF↑, *Ca+2↓, *lipid-P↓, *PGE2↓, *cognitive↑, *ChAT↑, *memory↑, *Dose↝, *toxicity↓,
3715- FA,  CUR,  PS,    The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice
- in-vivo, AD, NA
*cognitive↑, *IL1β↓, *Ach↑, *Aβ↓, *p‑tau↓, *BDNF↑, *APP↓,
4249- FA,    Folic acid supplementation during pregnancy prevents cognitive impairments and BDNF imbalance in the hippocampus of the offspring after neonatal hypoxia-ischemia
- in-vivo, NA, NA
*BDNF↑, *memory↑, *neuroP↑,
4251- FA,    Antidepressant-Like Effect of Ferulic Acid via Promotion of Energy Metabolism Activity
- in-vivo, NA, NA
*BDNF↑, *ATP↑, *Mood↑,
2861- FIS,    The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
- Review, Nor, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *Aβ↓, *12LOX↓, *COX2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑, *BDNF↑,
4250- Flav,    Dietary Flavonoids Interaction with CREB-BDNF Pathway: An 
Unconventional Approach for Comprehensive Management of Epilepsy
- Review, NA, NA
*ERK↑, *BDNF↑, *CREB↑,
6981- Form,    Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1↑, *p62↑, *COX2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, eff↑, *toxicity↓, *BioAv↑, *BioAv↑, *eff↑,
7040- GA,    Effects of gallic acid on acrylamide-induced endoplasmic reticulum stress, neuroinflammation and neuronal apoptosis in rats
- Trial, AD, NA
*SOD↑, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TNF-α↓, *IL1β↓, *BAX↓, *Casp3↓, *BDNF↑, *NRF2↑, *HO-1↑,
4248- Gala,    Meta-analysis of randomized controlled trials of galantamine in schizophrenia: significant cognitive enhancement
- Review, NA, NA
*BDNF↑, *cognitive↑,
4245- GBE,    Standardized extract of Ginkgo biloba enhances memory persistence over time
- in-vivo, AD, NA
*memory↑, *BDNF↑, *CREB↓, *BDNF↑,
4244- GBE,    Effects of Six-Week Ginkgo biloba Supplementation on Aerobic Performance, Blood Pro/Antioxidant Balance, and Serum Brain-Derived Neurotrophic Factor in Physically Active Men
- Human, Nor, NA
*BDNF∅,
7278- GGB,    Ginkgolide B: mechanisms of neurobiological effects, prospects for use in the therapy of Alzheimer's disease
- Review, AD, NA
*neuroP↑, *Aβ↓, *BDNF↑, *cognitive↑, *memory↑,
7270- GGB,    Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25-35 partly via up-regulation of brain-derived neurotrophic factor
- NA, AD, NA
*BDNF↑, *Apoptosis↓, *neuroP↑,
7217- GGB,    Role of Ginkgolides in the Inflammatory Immune Response of Neurological Diseases: A Review of Current Literatures
- Review, AD, NA
*eff↑, *AntiAg↑, *Apoptosis↓, *antiOx↑, *Inflam↓, *MAPK↓, *NF-kB↓, *PAF↓, *TLR1↓, *MyD88↓, *BDNF↑, *ROS↓, *PARP↓, *Cyt‑c↓,
4246- GI,    Ginger oil-loaded transdermal adhesive patch treats post-traumatic stress disorder
- in-vivo, NA, NA
*BDNF↑, *Inflam↓,
4247- GI,    6-Shogaol from Dried Ginger Protects against Intestinal Ischemia/Reperfusion by Inhibiting Cell Apoptosis via the BDNF/TrkB/PI3K/AKT Pathway
- vitro+vivo, NA, NA
*BDNF↑, *TrkB↑, *PI3K↑, *Akt↑, *Apoptosis↓, *Inflam↓, *antiOx↑,
4003- Gins,    Neuroprotective Potentials of Panax Ginseng Against Alzheimer's Disease: A Review of Preclinical and Clinical Evidences
- Review, adrenal, NA
*neuroP↑, *Inflam↓, *ROS↓, *BACE↓, *PPARγ↑, *Aβ↓, *p‑tau↓, *NF-kB↓, *IL1β↓, *IL6↓, *TNF-α↓, *ROS↓, *CREB↓, *BDNF↑, *memory↑,
4242- Gins,    Ginseng Extract G115 Attenuates Ethanol-Induced Depression in Mice by Increasing Brain BDNF Levels
- in-vivo, NA, NA
*BDNF↑, *Mood↑, *neuroP↑,
4243- Gins,    Effects of Ginseng on Neurological Disorders
- Review, Stroke, NA - Review, AD, NA - Review, Park, NA
*BDNF↑, *TrkB↑, *neuroP↑, *VEGF↑, *p‑tau↓, *memory↑,
3768- H2,    Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial
- Trial, AD, NA
*ROS↓, *NO↓, *BACE↓, *BDNF↑, *VEGF↑, *p‑tau↓, *MCP1/CCL2↓, *IL6↓, *cognitive↑, *toxicity∅,
3774- H2,    The role of hydrogen in Alzheimer’s disease
- Review, AD, NA
*Inflam↓, *antiOx↑, *NLRP3↓, *memory↑, *Aβ↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *p‑p38↓, *JNK↓, *ROS↓, *cognitive↑, *ER(estro)↑, *BDNF↑,
3776- H2,    The role of hydrogen in Alzheimer's disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *NLRP3↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *ROS↓, *BDNF↑,
3766- H2,    The role of hydrogen in Alzheimer′s disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *AMPK↑, *SIRT1↑, *FOXO↑, *mtDam↓, *neuroP↑, *ROS↓, *p38↓, *cognitive↑, *BDNF↑, *memory↑, *lipid-P↓, *IL6↓, *TNF-α↓, *JNK↓, *NF-kB↓, *NLRP3↓,

Showing Research Papers: 51 to 100 of 202
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 202

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx⇅, 1,   GSTs↑, 1,   HO-1↑, 1,   NRF2↑, 1,   ROS↑, 2,   ROS⇅, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Glycolysis↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,   Casp3↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,   Mcl-1↓, 1,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↓, 1,   PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   mitA↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CSCs↓, 1,   EMT↓, 1,   ERK↓, 1,   GSK‐3β↑, 1,   miR-34a↓, 1,   NOTCH1↓, 1,   STAT3↓, 1,   TumCG↓, 2,  

Migration(tgid=13) ⓘ

BACH1↓, 1,   Ki-67↓, 1,   LAMs↓, 1,   Slug↓, 1,   TRIB3↑, 1,   TumCI↓, 1,   TumCP↓, 1,   TumMeta↓, 1,   TumMeta↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

EGFR↓, 1,   Hif1a↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 1,   IL1β↓, 1,   NF-kB↓, 2,   NF-kB↑, 1,   PD-1↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 2,   ChemoSen↑, 3,   eff↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   Ki-67↓, 1,   TG/TAG↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   cognitive↑, 1,   NP/CIPN↓, 1,  
Total Targets: 60

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

PAF↓, 1,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 12,   ARE↑, 2,   Bil↑, 1,   Catalase↑, 4,   Fenton↓, 1,   GCLC↑, 1,   GCLM↑, 1,   GPx↑, 3,   GSH↑, 6,   HDL↑, 1,   HO-1↓, 1,   HO-1↑, 3,   Keap1↝, 1,   lipid-P↓, 7,   MDA↓, 3,   MPO↓, 1,   NQO1↑, 2,   NRF2↑, 7,   ROS↓, 15,   mt-ROS?, 1,   SOD↑, 6,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↓, 1,   ATP↓, 1,   ATP↑, 2,   Insulin↑, 1,   MMP↑, 1,   mtDam↓, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   p‑AKT1↑, 1,   ALAT↓, 2,   AMPK↓, 1,   AMPK↑, 4,   CREB↓, 2,   CREB↑, 3,   glucose↓, 1,   LDL↓, 2,   NAD↓, 1,   NADPH↓, 1,   PPARγ↑, 2,   SIRT1↑, 4,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↓, 4,   BAX↓, 2,   Bcl-2↓, 1,   Casp3↓, 3,   Casp9↓, 1,   Cyt‑c↓, 2,   GADD34↓, 1,   iNOS↓, 2,   JNK↓, 3,   MAPK↓, 1,   p‑MAPK↓, 1,   p38↓, 2,   p‑p38↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   other↓, 1,   other↑, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   HSPs↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1↓, 1,   Beclin-1↑, 1,   LC3II↓, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↓, 1,   PARP↓, 1,   PARP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   FOXO↑, 1,   FOXO3↑, 2,   GSK‐3β↓, 1,   mTOR↓, 1,   neuroG↑, 1,   PI3K↓, 1,   PI3K↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 2,   AntiAg↑, 1,   APP↓, 1,   Ca+2↓, 3,   CDK5↓, 1,   TG2/TGase↓, 2,   TXNIP↓, 1,   VCAM-1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↓, 1,   NO↓, 2,   NO↑, 1,   VEGF↑, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 4,   COX2↑, 1,   ICAM-1↓, 1,   IFN-γ↓, 1,   IL10↓, 1,   IL10↑, 1,   IL17↓, 2,   IL18↓, 1,   IL1β↓, 6,   IL23↓, 1,   IL6↓, 6,   IL6↑, 1,   IL8↓, 1,   Imm↓, 1,   Inflam↓, 14,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 2,   MyD88↓, 1,   NF-kB↓, 7,   PGE2↓, 3,   TLR1↓, 1,   TNF-α↓, 8,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 2,   AChE↓, 2,   BDNF↓, 1,   BDNF↑, 49,   BDNF∅, 1,   BrainVol↑, 1,   ChAT↑, 1,   GABA↑, 1,   MAOA↓, 1,   MAOA↑, 1,   NGF↑, 1,   PSD95↑, 1,   p‑tau↓, 6,   TrkB↑, 3,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 9,   BACE↓, 3,   NLRP3↓, 5,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER(estro)↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 3,   Dose↝, 2,   eff↑, 10,   Half-Life↝, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 2,   Bil↑, 1,   GutMicro↑, 2,   IL6↓, 6,   IL6↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 1,   AntiDiabetic↑, 2,   antiPs↑, 1,   chemoP↑, 1,   cognitive↑, 18,   hepatoP↑, 3,   memory↑, 15,   Mood↑, 3,   neuroP↑, 21,   Obesity↓, 1,   OS↑, 1,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 1,   Sleep↑, 1,   toxicity↓, 4,   toxicity↑, 1,   toxicity↝, 1,   toxicity∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   Bacteria↓, 2,  
Total Targets: 168

Scientific Paper Hit Count for: BDNF, brain-derived neurotrophic factor
11 Exercise
10 Hydrogen Gas
9 Magnetic Fields
6 Curcumin
6 Lycopene
6 Silymarin (Milk Thistle) silibinin
6 Vitamin D3
5 Apigenin (mainly Parsley)
5 Sulforaphane (mainly Broccoli)
5 Zinc
4 Ellagic acid
4 Ginseng
4 Honokiol
4 Huperzine A/Huperzia serrata
4 Lutein
4 Resveratrol
3 Carnosic acid
3 Caffeine
3 Cysteamine
3 Ferulic acid
3 Ginkgolide B
3 Naringin
3 Piperine
3 Urolithin
2 flavonoids
2 Aromatherapy
2 Baicalin
2 Berberine
2 Boron
2 Boswellia (frankincense)
2 Centella asiatica / Gotu kola → asiaticoside
2 Choline
2 Folic Acid, Vit B9
2 Chrysin
2 Cichoric acid / Chicoric acid
2 Coenzyme Q10
2 Crocetin
2 Docosahexaenoic Acid
2 diet Short Term Fasting
2 Eugenol
2 Ginkgo biloba
2 Ginger/6-Shogaol/Gingerol
2 Luteolin
2 Zeaxanthin
2 Magnesium
2 Phenylbutyrate
2 Propolis -bee glue
2 Quercetin
2 Sesame seeds and Oil
2 Taurine
2 Thymoquinone
2 Ursolic acid
1 Anthocyanins
1 Alpha-Lipoic-Acid
1 Acetyl-l-carnitine
1 alpha Linolenic acid
1 Artemisinin
1 Astaxanthin
1 Baicalein
1 Beta-Caryophyllene
1 Betulinic acid
1 Bacopa monnieri
1 Caffeic acid
1 Capsaicin
1 Carvacrol
1 Carnosine
1 chitosan
1 Vitamin B12
1 Vitamin B2,Riboflavin
1 Echinacea
1 Cinnamon
1 dietMediterranean
1 2-DeoxyGlucose
1 Calorie Restriction Mimetics
1 EGCG (Epigallocatechin Gallate)
1 Emodin
1 Phosphatidylserine
1 Fisetin
1 Formononetin
1 Gallic acid
1 Galantamine
1 Lecithin
1 Magnolol
1 Magnetic Field Rotating
1 Moringa oleifera
1 Methylsulfonylmethane
1 Mushroom Lion’s Mane
1 nicotinamide adenine dinucleotide
1 probiotics
1 Pterostilbene
1 Salvia officinalis
1 Rosmarinic acid
1 Selenium
1 Shikonin
1 Selenite (Sodium)
1 Safflower yellow
1 Turmerones
1 Vitamin B6,pyridoxine
1 Vitamin E
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1356  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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