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| Type: |
| Brain-Derived Neurotrophic Factor (BDNF) is a key neurotrophin (a type of growth factor) involved in brain health, and its role in Alzheimer’s Disease (AD) has been extensively studied. -AD patients often have lower BDNF levels in key brain regions, such as the hippocampus and cortex. -This reduction correlates with cognitive decline and brain atrophy. -BDNF normally protects neurons from Aβ toxicity -Exercise and cognitive training have been shown to boost BDNF levels and may slow cognitive decline. - natural compounds (like curcumin or flavonoids) may also upregulate BDNF. |
| 4159- | dietSTF, | 2DG, | CRMs, | Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms |
| - | Review, | AD, | NA |
| 4252- | EA, | Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression |
| - | in-vivo, | NA, | NA |
| - | Human, | MS, | NA | - | NA, | IBD, | NA |
| 4254- | EA, | Chronic administration of ellagic acid improved the cognition in middle-aged overweight men |
| - | Human, | Obesity, | NA |
| 4255- | EA, | Effects of nutritional interventions on BDNF concentrations in humans: a systematic review |
| - | Review, | NA, | NA |
| 4152- | EGCG, | Green tea catechins potentiate the neuritogenic action of brain-derived neurotrophic factor: role of 67-kDa laminin receptor and hydrogen peroxide |
| - | in-vitro, | AD, | NA |
| 4140- | Ex, | Experimental and clinical evidence of physical exercise on BDNF and cognitive function: A comprehensive review from molecular basis to therapy |
| - | Review, | AD, | NA |
| 4174- | Ex, | Exercise-Mediated Neurogenesis in the Hippocampus via BDNF |
| - | Review, | NA, | NA |
| 4155- | Ex, | Prior regular exercise reverses the decreased effects of sleep deprivation on brain-derived neurotrophic factor levels in the hippocampus of ovariectomized female rats |
| - | in-vivo, | AD, | NA |
| 4139- | Ex, | Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases |
| - | Review, | AD, | NA |
| 4141- | Ex, | Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis |
| - | Review, | AD, | NA |
| 4142- | Ex, | Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 4143- | Ex, | Brain-Derived Neurotrophic Factor: A Connecting Link Between Nutrition, Lifestyle, and Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 4144- | Ex, | Exploring the impact of exercise-induced BDNF on neuroplasticity in neurodegenerative and neuropsychiatric conditions |
| - | Review, | AD, | NA |
| 4145- | Ex, | Effects of different physical activities on brain-derived neurotrophic factor: A systematic review and bayesian network meta-analysis |
| - | Review, | AD, | NA |
| 4249- | FA, | Folic acid supplementation during pregnancy prevents cognitive impairments and BDNF imbalance in the hippocampus of the offspring after neonatal hypoxia-ischemia |
| - | in-vivo, | NA, | NA |
| 4251- | FA, | Antidepressant-Like Effect of Ferulic Acid via Promotion of Energy Metabolism Activity |
| - | in-vivo, | NA, | NA |
| 3714- | FA, | Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review |
| - | Review, | AD, | NA |
| 3715- | FA, | CUR, | PS, | The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice |
| - | in-vivo, | AD, | NA |
| 2861- | FIS, | The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress |
| - | Review, | Nor, | NA | - | Review, | Stroke, | NA | - | Review, | Park, | NA |
| 4250- | Flav, | Dietary Flavonoids Interaction with CREB-BDNF Pathway: An Unconventional Approach for Comprehensive Management of Epilepsy |
| - | Review, | NA, | NA |
| 4248- | Gala, | Meta-analysis of randomized controlled trials of galantamine in schizophrenia: significant cognitive enhancement |
| - | Review, | NA, | NA |
| 4245- | Gb, | Standardized extract of Ginkgo biloba enhances memory persistence over time |
| - | in-vivo, | NA, | NA |
| 4244- | Gb, | Effects of Six-Week Ginkgo biloba Supplementation on Aerobic Performance, Blood Pro/Antioxidant Balance, and Serum Brain-Derived Neurotrophic Factor in Physically Active Men |
| - | Human, | Nor, | NA |
| 4246- | GI, | Ginger oil-loaded transdermal adhesive patch treats post-traumatic stress disorder |
| - | in-vivo, | NA, | NA |
| 4247- | GI, | 6-Shogaol from Dried Ginger Protects against Intestinal Ischemia/Reperfusion by Inhibiting Cell Apoptosis via the BDNF/TrkB/PI3K/AKT Pathway |
| - | vitro+vivo, | NA, | NA |
| 4003- | Gins, | Neuroprotective Potentials of Panax Ginseng Against Alzheimer's Disease: A Review of Preclinical and Clinical Evidences |
| - | Review, | adrenal, | NA |
| 4242- | Gins, | Ginseng Extract G115 Attenuates Ethanol-Induced Depression in Mice by Increasing Brain BDNF Levels |
| - | in-vivo, | NA, | NA |
| 4243- | Gins, | Effects of Ginseng on Neurological Disorders |
| - | Review, | Stroke, | NA | - | Review, | AD, | NA | - | Review, | Park, | NA |
| 4237- | H2, | Hydrogen-Rich Saline Protects Against Spinal Cord Injury in Rats |
| - | in-vitro, | NA, | NA |
| 4236- | H2, | Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model |
| - | in-vivo, | Stroke, | NA |
| - | in-vivo, | Sepsis, | NA |
| 4234- | H2, | Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice |
| - | in-vivo, | Sepsis, | NA |
| 4307- | H2, | Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models |
| - | in-vivo, | AD, | NA |
| 3768- | H2, | Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial |
| - | Trial, | AD, | NA |
| 3774- | H2, | The role of hydrogen in Alzheimer’s disease |
| - | Review, | AD, | NA |
| 3776- | H2, | The role of hydrogen in Alzheimer's disease |
| - | Review, | AD, | NA |
| 3766- | H2, | The role of hydrogen in Alzheimer′s disease |
| - | Review, | AD, | NA |
| 3767- | H2, | The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges |
| - | Review, | AD, | NA |
| 4239- | HNK, | Honokiol reverses depressive-like behavior and decrease in brain BDNF levels induced by chronic corticosterone injections in mice |
| - | in-vivo, | NA, | NA |
| - | in-vivo, | NA, | NA |
| 4238- | HNK, | Neuropharmacological potential of honokiol and its derivatives from Chinese herb Magnolia species: understandings from therapeutic viewpoint |
| - | Review, | AD, | NA | - | NA, | Park, | NA |
| 4241- | HNK, | Effects of Honokiol on Neurological Injury and Cognitive Function in Mice with Intracerebral Hemorrhage by Regulating BDNF-TrkB-CREB Signaling Pathway |
| - | in-vivo, | Stroke, | NA |
| 4212- | Hup, | Huperzine A Alleviates Oxidative Glutamate Toxicity in Hippocampal HT22 Cells via Activating BDNF/TrkB-Dependent PI3K/Akt/mTOR Signaling Pathway |
| - | in-vitro, | Nor, | HT22 |
| 4213- | Hup, | Huperzine A-Liposomes Efficiently Improve Neural Injury in the Hippocampus of Mice with Chronic Intermittent Hypoxia |
| - | in-vivo, | NA, | NA |
| 4209- | Hup, | Huperzine A, reduces brain iron overload and alleviates cognitive deficit in mice exposed to chronic intermittent hypoxia |
| - | in-vivo, | NA, | NA |
| 4210- | Hup, | A Synopsis of Multitarget Potential Therapeutic Effects of Huperzine A in Diverse Pathologies–Emphasis on Alzheimer’s Disease Pathogenesis |
| - | Review, | AD, | NA |
| 4233- | LEC, | Lecithinized brain-derived neurotrophic factor promotes the differentiation of embryonic stem cells in vitro and in vivo |
| - | in-vitro, | Nor, | NA |
| 4293- | LT, | Regulatory Role of NF-κB on HDAC2 and Tau Hyperphosphorylation in Diabetic Encephalopathy and the Therapeutic Potential of Luteolin |
| - | in-vivo, | Diabetic, | NA |
| 4292- | LT, | Luteolin for neurodegenerative diseases: a review |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | MS, | NA | - | Review, | Stroke, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1356 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid