Mcl-1 Cancer Research Results

Mcl-1, myeloid cell leukemia 1: Click to Expand ⟱
Source: HalifaxProj(inhibit)
Type:
A member of the Bcl-2 family of proteins, which play a crucial role in regulating apoptosis, or programmed cell death. In cancer, Mcl-1 is often overexpressed, contributing to the development and progression of various types of tumors.
Mcl-1 is often overexpressed in several cancers, including hematological malignancies (like leukemia and lymphoma) and solid tumors (such as breast, lung, and prostate cancers).
Mcl-1 inhibits apoptosis by binding to pro-apoptotic proteins, preventing them from triggering the cell death pathway.


Scientific Papers found: Click to Expand⟱
1155- Fuc,    The anti-cancer effects of fucoidan: a review of both in vivo and in vitro investigations
- Review, Var, NA
*toxicity↓, Casp3↑, Casp7↑, Casp8↑, Casp9↑, VEGF↓, angioG↓, PI3K↓, Akt↓, PARP↑, Bak↑, BID↑, Fas↑, Mcl-1↓, survivin↓, XIAP↓, ERK↓, EMT↓, EM↑, IM↓, Snail↓, Slug↓, Twist↓,
5205- Gallo,    Evaluation of the anti-tumor effects of lactate dehydrogenase inhibitor galloflavin in endometrial cancer cells
- in-vitro, Endo, ISH
LDH↓, TumCG↓, LDHA↓, Apoptosis↑, cl‑Casp3↑, Mcl-1↓, Bcl-2↓, TumCCA↑, ROS↑, mt-DNAdam↑, GlucoseCon↓, ATP↓, PDH↑, Pyruv↑, Glycolysis↓, TCA↑, cMyc↓, E-cadherin↑, Slug↓,
7065- GamB,    Gambogic acid: A review of its pharmacological mechanisms against cancer
- Review, Var, NA
AntiTum↑, Apoptosis↑, TumCCA↑, angioG↓, Hif1a↓, VEGF↓, MMPs↓, TumMeta↓, NF-kB↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, P-gp/ABCB1↓, Shh↓, Pyro↑, Casp3↑, GSDME↑, ChemoSen↑, RadioS↑, BioAv↓, Bcl-2↓, Mcl-1↓, BAX↑, Half-Life↓, ROS↑, miR-21↓, MMP2↓, MMP9↓,
7059- GamB,    Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells
- in-vitro, CRC, HCT15
TumCP↓, Apoptosis↑, JNK↑, TumCCA↑, cycD1/CCND1↓, P53↑, Casp3↑, Casp8↑, Casp9↑, cl‑PARP↑, MMP↓, Cyt‑c↑, Bcl-2↓, Bcl-xL↓, Mcl-1↓, XIAP↓, survivin↓,
7067- GamB,    Gambogic Acid and Its Role in Chronic Diseases
- Review, Var, NA
*NF-kB↓, PI3K↓, Akt↓, STAT3↓, STAT5↓, IL6↓, COX2/PTGS2↓, iNOS↓, MMPs↓, Src↓, PKA↓, CXCR4↑, VEGF↓, Bcl-2↓, Bcl-xL↓, IAP1↓, Mcl-1↓, survivin↓, cycD1/CCND1↓, HSP90↓, HSP70/HSPA5↓, MAPK↓, HATs↓, HDAC↓, FAK↓, ROS↑, MMP7↓, MMP9↓, α-tubulin↑, cl‑PARP↑, TNF-α↓, BID↑, BAD↑, Cyt‑c↑, Casp3↑, Casp9↑, *AntiArt↑, *antiPs↑,
7086- GAR,    Garcinol: An emerging epigenetic modifier with versatile anticancer properties
- Review, Var, NA
AntiCan↑, TumCG↓, TumMeta↓, toxicity↓, Apoptosis↑, angioG↓, *BioAv↝, HATs↓, p300↓, CBP↓, PI3K↓, Akt↓, NF-kB↓, STAT↓, mTOR↓, DFF45↓, survivin↓, N-cadherin↓, Twist↓, MMP2↓, MMP3↓, MMP9↓, Mcl-1↓, EZH2↓, NOTCH↓, CXCR4↓, PGE2↓, VEGF↓, mPGES-1↓, CycB/CCNB1↓, CDK2↓, CDK4/6↓, iNOS↓, COX2/PTGS2↓, IL1↓, TNF-α↓, PARP↑, Bcl-2↓, CompStab↝,
816- GAR,    Garcinol downregulates Notch1 signaling via modulating miR-200c and suppresses oncogenic properties of PANC-1 cancer stem-like cells
- in-vitro, PC, PANC1
Mcl-1↓, EZH2↓, ABCG2↓, Gli1↓, NOTCH1↓, miR-200c↑,
826- GAR,    Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo
- vitro+vivo, HCC, HepG2 - vitro+vivo, Liver, HUH7
STAT3↓, TumCP↓, cycD1/CCND1↓, Bcl-2↓, Bcl-xL↓, Mcl-1↓, survivin↓, VEGF↓, TumCCA↑, TumVol↓,
7319- Gos,    BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides
- in-vitro, PC, NA
eff↑, Ca+2↑, BAX↑, Bcl-2↓, Bcl-xL↓, Mcl-1↓, RadioS↑,
7320- Gos,    AT-101 Enhances the Antitumor Activity of Lenalidomide in Patients with Multiple Myeloma
- Trial, Melanoma, NA
Bcl-2↓, Mcl-1↓, Apoptosis↑, Synergy↑, toxicity↝, ORR↑,
7318- Gos,    -(-)Gossypol promotes the apoptosis of bladder cancer cells in vitro
- in-vitro, Bladder, NA
ChemoSen↑, Bcl-2↓, Mcl-1↓, BIM↑, PUMA↑,
7317- Gos,    A phase II study of AT-101 (gossypol) in chemotherapy-sensitive recurrent extensive stage small cell lung cancer (ES-SCLC)
- Trial, Lung, NA
Bcl-2↓, Bcl-xL↓, Mcl-1↓, NOXA↑, PUMA↑, Dose↝, eff↓,
7316- Gos,  PacT,  carbop,  Chemo,    A phase I study of AT-101, a BH3 mimetic, in combination with paclitaxel and carboplatin in solid tumors
- Trial, Var, NA
Bcl-2↓, Bcl-xL↓, Mcl-1↓, Dose↝, toxicity↝,
7312- Gos,    A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum
- vitro+vivo, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145
eff↑, TumAuto↑, TumCG↓, Bcl-2↓, Bcl-xL↓, Mcl-1↓, Apoptosis↑, eff↑,
7309- Gos,    Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa
- vitro+vivo, Pca, PC3
Bcl-2↓, Bcl-xL↓, Mcl-1↓, TumCG↓, Apoptosis↓, ChemoSen↑,
7370- HibSad,    Hibiscus sabdariffa leaf induces apoptosis of human prostate cancer cells in vitro and in vivo
- vitro+vivo, Pca, LNCaP - in-vitro, Pca, PC3 - in-vitro, Pca, DU145
eff↑, Dose↝, Bcl-2↓, Mcl-1↓, BAX↑, Cyt‑c↑, FasL↑, eff↑, TumW↓, TumVol↓, other↝,
7350- HibSad,    Hibiscus polyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathway
- in-vitro, GC, AGS
TumCD↑, DNAdam↑, P53↑, Bcl-2↓, Mcl-1↓, Cyt‑c↑, FasL↑, Fas↑, p38↑, BAX↑, Dose↝, TumCCA↑,
2881- HNK,    Honokiol Suppressed Pancreatic Cancer Progression via miR-101/Mcl-1 Axis
- in-vitro, PC, PANC1
tumCV↓, Casp3↑, Apoptosis↑, TumCCA↑, TumCI↓, Mcl-1↓, EMT↓,
2864- HNK,    Honokiol: A Review of Its Anticancer Potential and Mechanisms
- Review, Var, NA
TumCCA↑, CDK2↓, EMT↓, MMPs↓, AMPK↑, TumCI↓, TumCMig↓, TumMeta↓, VEGFR2/KDR/Flk1↓, *antiOx↑, *Inflam↓, *BBB↑, *neuroP↑, *ROS↓, Dose↝, selectivity↑, Casp3↑, Casp9↑, NOTCH1↓, cycD1/CCND1↓, cMyc↓, P21?, DR5↑, cl‑PARP↑, P53↑, Mcl-1↑, p65↓, NF-kB↓, ROS↑, JNK↑, NRF2↑, cJun↑, EF-1α↓, MAPK↓, PI3K↓, mTORC1↓, CSCs↓, OCT4↓, Nanog↓, SOX4↓, STAT3↓, CDK4↓, p‑RB1↓, PGE2↓, COX2/PTGS2↓, β-catenin/ZEB1↑, IKKα↓, HDAC↓, HATs↑, H3↑, H4↑, LC3II↑, c-Raf↓, SIRT3↑, Hif1a↓, ER Stress↑, GRP78/BiP↑, cl‑CHOP/DDIT3↑, MMP↓, PCNA↓, Zeb1↓, NOTCH3↓, CD133↓, Nestin↓, ATG5↑, ATG7↑, survivin↓, ChemoSen↑, SOX2↓, OS↑, P-gp/ABCB1↓, Half-Life↓, Half-Life↝, Synergy↑, BioAv↓,
4640- HT,    The anti-cancer potential of hydroxytyrosol
- Review, Var, NA
selectivity↑, MMP↓, Cyt‑c↑, Casp9↑, Casp3↑, Bcl-2↓, BAX↑, MPT↑, Fas↑, PI3K↓, Akt↓, mTOR↓, Mcl-1↓, survivin↓, STAT3↓, EMT↓, TumCI↓, angioG↓, E-cadherin↑, N-cadherin↓, Snail↓, Twist↓, MMPs↓, MMP2↓, MMP9↓, VEGF↓, VEGFR2/KDR/Flk1↓, Hif1a↓, CSCs↓, CD44↓, Wnt↓, β-catenin/ZEB1↓,
7772- IBC,    Isobavachalcone inhibits acute myeloid leukemia: Potential role for ROS-dependent mitochondrial apoptosis and differentiation
- vitro+vivo, AML, NA
Apoptosis↑, Diff↑, tumCV↓, TumCP↓, MMP↓, BAX↑, Bcl-2↓, Bcl-xL↓, Mcl-1↓, Cyt‑c↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, p‑MEK↑, p‑ERK↑, ROS↑, eff↓,
7853- isoO,    Natural flavonoid isoorientin and its anticancer mechanisms: a systematic review
- Review, Var, NA
Apoptosis↑, TumCCA↑, MAPK?, PI3K↓, Akt↓, AMPK?, NF-kB?, Wnt↓, β-catenin/ZEB1↓, Bcl-2↓, Mcl-1↓, BAX↑, Cyt‑c↑, Casp↑, TumCP↓, TumMeta↓,
7894- IVT,    Isovitexin Inhibits Stemness and Induces Apoptosis in Hepatocellular Carcinoma SK-Hep-1 Spheroids by Upregulating miR-34a Expression
- in-vitro, HCC, SK-HEP-1
CD44↓, CSCs↓, ABCG2↓, ALDH1A1↓, Nanog↓, miR-34a↑, BAX↑, Bcl-2↓, Mcl-1↓, Apoptosis↑,
8090- KAE,    A systematic review of anti-cancer roles and mechanisms of kaempferol as a natural compound
- Review, Nor, NA
*cardioP↑, *AntiCan↑, *Inflam↓, *neuroP↑, *BioAv↓, selectivity?, p‑Akt↓, p‑cycD1/CCND1↓, p‑CDK4↓, p‑BID↓, p‑Mcl-1↓, p‑BRCA1↑, ATM↑, P53↑, P21↑, p38↑, BAX↑, BID↑, MMP↓, Casp3↑, Casp7↑, Casp9↑, AIF↑, ER Stress↑, TumMeta↓, ERK↓, AP-1↓, JNK↓, p38↓, GLUT1↓, GlucoseCon↓, MMP9↓, CYP1A1↓, ChemoSen↑, OCT4↓, Nanog↓, P-gp/ABCB1↓, ALDH1A1↓, TumCCA↑, DNAdam↑, γH2AX↑, COX2/PTGS2↓, i-ROS↓, Ca+2↓, eff↑, DR5↑, ChemoSen↑, Akt↓, PI3K↓, ROS↑, EMT↓, survivin↓,
8253- LCA,    Licochalcone A, a natural chalconoid isolated from Glycyrrhiza inflata root, induces apoptosis via Sp1 and Sp1 regulatory proteins in oral squamous cell carcinoma
- in-vitro, SCC, HSC4
*AntiTum↑, *angioG↓, *AntiP↑, *antiOx↑, *Bacteria↓, *Inflam↓, tumCV↓, Sp1/3/4↓, p27/CDKN1B↑, P21↑, cycD1/CCND1↓, Mcl-1↓, survivin↓, Apoptosis↑,
8196- LGE,    Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents
- in-vitro, Lung, NA
Bcl-xL↓, Mcl-1↓, TumCP↓, STAT3↑, TumCP?,
8401- LT,    Multi-Faceted Role of Luteolin in Cancer Metastasis: EMT, Angiogenesis, ECM Degradation and Apoptosis
- Review, Var, NA
EMT↓, N-cadherin↓, Vim↓, VEGF↓, VEGFR1↓, MMPs↓, Telomerase↓, NF-kB↓, cMyc↓, Bax:Bcl2↑, Casp3↑, PI3K↓, Akt↓, FOXO3↑, P21↑, p27/CDKN1B↑, cl‑PARP↑, Cyt‑c↑, NOTCH↓, HES1↓, ROS↑, SOD↓, miR-34b-5p↑, Hif1a↓, P21↓, survivin↓, Mcl-1?, Bcl-xL↓, MDM2↓, MMP2↓, MMP9↓, MMP3↓, MMP16↓, miR-384↑, NRF2↓, HO-1↓, angioG↓,
2924- LT,    Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1
- in-vitro, GC, NA - in-vivo, NA, NA
p‑STAT3↓, STAT3↓, Mcl-1↓, survivin↓, Bcl-xL↓, HSP90↓,
2912- LT,    Luteolin: a flavonoid with a multifaceted anticancer potential
- Review, Var, NA
ROS↑, TumCCA↑, TumCP↓, angioG↓, ER Stress↑, mtDam↑, PERK↑, ATF4↑, eIF2α↑, cl‑Casp12↑, EMT↓, E-cadherin↑, N-cadherin↓, Vim↓, *neuroP↑, NF-kB↓, PI3K↓, Akt↑, XIAP↓, MMP↓, Ca+2↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, Cyt‑c↑, IronCh↑, SOD↓, *ROS↓, *LDHA↑, *SOD↑, *GSH↑, *BioAv↓, Telomerase↓, cMyc↓, hTERT/TERT↓, DR5↑, Fas↑, FADD↑, BAD↑, BOK↑, BID↑, NAIP↓, Mcl-1↓, CDK2↓, CDK4↓, MAPK↓, AKT1↓, Akt2↓, *Beclin-1/ATG6↓, Hif1a↓, LC3II↑, Beclin-1/ATG6↑,
2533- M-Blu,  PDT,    Methylene blue-mediated photodynamic therapy enhances apoptosis in lung cancer cells
- in-vitro, Lung, A549
MMP↓, p‑MAPK↑, ROS↑, cl‑PARP↑, Bcl-2↓, Mcl-1↓, eff↓,
4514- MAG,    Magnolol and its semi-synthetic derivatives: a comprehensive review of anti-cancer mechanisms, pharmacokinetics, and future therapeutic potential
- Review, Var, NA
AntiCan↑, TumCP↓, TumCCA↑, TumMeta↓, angioG↓, NF-kB↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, BioAv↓, *antiOx↑, *Inflam↓, *AntiAg↑, ChemoSen↑, cycD1/CCND1↓, CycB/CCNB1↓, cycE/CCNE↓, CDK2↓, CDK4↓, p27/CDKN1B↑, P21↑, P53↑, PTEN↓, XIAP↓, Mcl-1↓, Casp3↑, Casp9↑, MMP9↑,
4353- MF,  Chemo,    Pulsed Electromagnetic Field Enhances Doxorubicin-induced Reduction in the Viability of MCF-7 Breast Cancer Cells
- in-vitro, BC, MCF7
TumCCA↑, Apoptosis↑, ChemoSen↑, TumCCA↑, Casp↝, p‑CDK2↓, cycE/CCNE↓, Fas↑, BAX↑, survivin↓, Mcl-1↓, cl‑PARP↑, cl‑Casp7↑, cl‑Casp8↑, cl‑Casp9↑,
9074- MGF,    Mangiferin prevents the growth of gastric carcinoma by blocking the PI3K-Akt signalling pathway
- in-vitro, GC, SGC-7901 - in-vitro, GC, BGC-823
TumCP↓, Dose?, Bcl-2↓, Bcl-xL↓, Mcl-1↓, BAX↑, BAD?, cl‑Casp3↑, cl‑Casp9↑, p‑PI3K↓, p‑Akt↓, p‑mTOR↓, toxicity↓,
8675- MLT,    Melatonin combined with antineoplastic drugs or natural products for cancer treatment: An update
- Review, Var, NA
ChemoSen↑, TumCP↓, TumCMig↓, CSCs↓, MDR1↓, chemoP?, IL1β↓, IL6↓, IL8↓, TNF-α↓, COX2/PTGS2↓, iNOS↓, Bcl-2↓, Mcl-1↓, IAP1↓, survivin↓, PCNA↓, Ki-67↓, CC(CDKs/cyclins)↓, TumCMig↓, TumCI↓, Fibronectin↓, Vim↓, N-cadherin↓, MMP2↓, MMP9↓, Synergy↑, Synergy↑, OCT4↓, Nanog↓, ERCC1↓, P-gp/ABCB1↓, EMT↓, Synergy↑, ChemoSen↑,
8893- MOR,    Flavonoid morin inhibits proliferation and induces apoptosis of melanoma cells by regulating reactive oxygen species, Sp1 and Mcl-1
- in-vitro, Melanoma, NA
ROS↑, Apoptosis↑, Sp1/3/4↓, Mcl-1↓, Bcl-2↓, Casp3↑, BAX↑, PUMA↑,
8859- MOR,    Morin inhibits STAT3 tyrosine 705 phosphorylation in tumor cells through activation of protein tyrosine phosphatase SHP1
- in-vitro, Melanoma, U266 - in-vitro, BC, MCF7 - in-vitro, SCC, SCC4 - in-vitro, BC, MCF-10AT
STAT3↓, Src↓, JAK1↓, JAK2↓, PIAS-3↑, ChemoSen↑, SHP1↑, XIAP↓, cFLIP↓, Mcl-1↓, survivin↓, Bcl-2↓, Bcl-xL↓, IAP2/BIRC3↓, Casp8↑, Casp9↑, Casp3↑, cl‑PARP↑, selectivity↑,
930- MushShi,    Active Hexose Correlated Compound (AHCC) Inhibits the Proliferation of Ovarian Cancer Cells by Suppressing Signal Transducer and Activator of Transcription 3 (STAT3) Activation
- in-vitro, Ovarian, NA
p‑STAT3↓, PTPN6↑, cycD1/CCND1↓, Bcl-2↓, Mcl-1↓, survivin↓, VEGF↓,
1807- NarG,    A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies
- Review, Var, NA
AntiTum↑, TumCP↓, tumCV↓, TumCCA↑, Mcl-1↓, RAS↓, e-Raf↓, VEGF↓, AntiAg↑, MMP2↓, MMP9↓, TIMP2↑, TIMP1↑, p38↓, Wnt↓, β-catenin/ZEB1↑, Casp↑, P53↑, BAX↑, COX2/PTGS2↓, GLO-I↓, CYP1A1↑, lipid-P↓, p‑Akt↓, p‑mTOR↓, VCAM-1↓, P-gp/ABCB1↓, survivin↓, Bcl-2↓, ROS↑, ROS↑, MAPK↑, STAT3↓, chemoP↑,
6492- Nimb,    Review on Molecular and Chemopreventive Potential of Nimbolide in Cancer
- Review, Var, NA
Apoptosis↑, TumCCA↑, TumCP↓, TumCI↓, angioG↓, TumMeta↓, PTEN↑, NF-kB↓, Wnt↓, β-catenin/ZEB1↓, IKKα↓, CXCR2↓, CXCR4↓, Bcl-2↓, COX2/PTGS2↓, MMP9↓, VEGF↓, TIMP2↑, chemoPv↑, ROS↑, DR4↑, P53↑, BAX↑, Casp3↑, Casp8↑, Casp9↑, cl‑PARP↑, Mcl-1↓, XIAP↓, survivin↓, FasL↑, FADD↑, EGFR↓, MMPs↓,
6493- Nimb,    Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment
- in-vivo, CRC, HCT116 - vitro+vivo, CRC, HT29
TumCP↓, Apoptosis↑, NF-kB↓, IKKα↓, Bcl-2↓, Bcl-xL↓, survivin↓, Mcl-1↓, cMyc↓, cycD1/CCND1↓, MMP9↓, CXCR4↓, ICAM-1↓, VEGF↓, angioG↓, TumCG↓,
4627- OLE,    Oleuropein regulates ubiquitination-mediated Mcl-1 turnover and exhibits antitumor activity
- in-vitro, Oral, NA
tumCV↓, Mcl-1↓, TumCG↓, toxicity∅, RadioS↑, AntiTum↑,
9046- PatchO,    Patchouli alcohol suppresses castration-resistant prostate cancer progression by inhibiting NF-κB signal pathways
- in-vitro, Pca, DU145 - in-vitro, Pca, PC3
TumCMig↓, TumCI↓, TumCP↓, Apoptosis↑, MMP↓, cl‑Casp3↑, cl‑PARP↑, BAX↑, Bcl-2↓, Ki-67↓, Mcl-1↓, NF-kB↓, p65↓, MMP2↓, MMP7↓, MMP9↓, VEGF↓, TumCG↓, Dose↝,
4953- PEITC,    PEITC: a natural compound effective in killing primary leukemia cells and overcoming drug resistance
- in-vitro, CLL, NA
ROS↑, GSH↓, TumCD↓, eff↓, Mcl-1↓, Casp3↑,
4918- PEITC,    Nutritional Sources and Anticancer Potential of Phenethyl Isothiocyanate: Molecular Mechanisms and Therapeutic Insights
- Review, Var, NA
Apoptosis↑, TumCP↓, angioG↓, TumMeta↓, NF-kB↓, Akt↓, MAPK↓, *BioAv↓, ROS↑, lipid-P↑, AIF↑, Cyt‑c↑, DR4↑, DR5↑, TumCCA↑, JAK↓, STAT3↓, MMP2↓, MMP9↓, PKCδ↓, Hif1a↓, JNK↓, Mcl-1↓, COX2/PTGS2↓, MMP↓, Casp3↑, ChemoSen↑, *BioAv↓, Half-Life↓,
5184- PEITC,    Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways
- vitro+vivo, AML, U937
Casp3↑, Casp9↑, Casp8↑, cl‑PARP↑, Apoptosis↑, Mcl-1↓, Akt↓, JNK↑, eff↑,
2950- PL,    Overview of piperlongumine analogues and their therapeutic potential
- Review, Var, NA
AntiAg↑, neuroP↑, Inflam↓, NO↓, PGE2↓, MMP3↓, MMP13↓, TumCMig↓, TumCI↓, p38↑, JNK↑, NF-kB↑, ROS↑, FOXM1↓, TrxR1↓, GSH↓, Trx↓, cMyc↓, Casp3↑, Bcl-2↓, Mcl-1↓, STAT3↓, AR↓, DNAdam↑,
3378- QC,    CK2 and PI3K are direct molecular targets of quercetin in chronic lymphocytic leukaemia
- in-vitro, AML, NA
CK2↓, PI3K↓, TumCD↑, Akt↓, Mcl-1↓, PTEN↑,
50- QC,    Anticancer effect and mechanism of polymer micelle-encapsulated quercetin on ovarian cancer
- vitro+vivo, Ovarian, A2780S
Casp3↑, Casp9↑, Mcl-1↓, Bcl-2↓, BAX↑, angioG↓, TumCG↓, Apoptosis↑, p‑p44↓, Akt↓, TumCP↓, eff↑,
76- QC,    Multifaceted preventive effects of single agent quercetin on a human prostate adenocarcinoma cell line (PC-3): implications for nutritional transcriptomics and multi-target therapy
- in-vitro, Pca, PC3
aSmase↝, Diablo↑, Fas↓, Hsc70↓, Hif1a↓, Mcl-1↓, HSP90↓, FLT4↓, EphB4↓, DNA-PK↓, PARP1↓, ATM↓, XIAP↝, PLC↓, GnT-V↝, heparanase↝, NM23↑, CSR1↑, SPP1↓, DNMT1↓, HDAC4↓, CXCR4↓, β-catenin/ZEB1↓, FBXW7↝, AMACR↓, cycD1/CCND1↓, IGF-1R↓, IMPDH1↓, IMPDH2↓, HEC1↓, NHE1↓, NOS2↓,
881- RES,    Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein
- in-vitro, BC, MDA-MB-231 - in-vitro, PC, PANC1 - in-vitro, Pca, DU145
TumCCA↑, cycD1/CCND1↓, Bcl-xL↓, Mcl-1↓, other↓,

Showing Research Papers: 51 to 100 of 110
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 110

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   frataxin↑, 1,   GSH↓, 5,   GSR↑, 1,   GSTs↓, 1,   HO-1↓, 3,   HO-1↑, 4,   HO-2↓, 1,   Keap1↓, 1,   lipid-P↓, 2,   lipid-P↑, 5,   NQO1↑, 1,   NRF2↓, 4,   NRF2↑, 5,   PAO↑, 1,   Prx6↑, 1,   ROS↓, 3,   ROS↑, 51,   ROS⇅, 3,   i-ROS↓, 1,   SOD↓, 2,   Trx↓, 1,   ox-Trx1↑, 1,   TrxR↓, 1,   TrxR1↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 4,   CDC25↓, 2,   EGF↓, 1,   MCU↓, 1,   mitResp↓, 2,   mtDam↑, 3,   OCR↓, 1,   OXPHOS↓, 2,   mt-OXPHOS↓, 2,   PDH↓, 3,   PDH↑, 1,   PINK1↑, 1,   SDH↓, 1,   SIRT3↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 2,   5LO↓, 1,   ACC↑, 3,   ACLY↓, 2,   ALAT↓, 2,   AMACR↓, 1,   AMPK?, 1,   AMPK↑, 7,   ATP↓, 6,   citrate↓, 1,   CPT1A↓, 1,   ECAR↝, 1,   ENO1↓, 1,   FASN↑, 2,   FBPase↑, 2,   GAPDH↓, 2,   GLO-I↓, 1,   glucoNG↑, 2,   GlucoseCon↓, 4,   GlutaM↓, 1,   Glycolysis↓, 8,   GSK‐3β↓, 3,   GSK‐3β↑, 3,   HK2↓, 5,   lactateProd↓, 2,   LDHA↓, 3,   LDL↓, 1,   NADPH↓, 1,   NADPH↑, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 2,   PFK↓, 1,   PFK1↓, 2,   PFK2?, 1,   PFK2↓, 2,   PKM2↓, 2,   Pyruv↑, 1,   SIRT1↓, 1,   SIRT1↑, 1,   SSAT↑, 1,   TCA↓, 3,   TCA↑, 2,   β-oxidation↓, 2,  

Cell Death(tgid=5) ⓘ

AIF↑, 5,   APAF1↑, 2,   Apoptosis↓, 2,   Apoptosis↑, 36,   aSmase↝, 1,   BAD?, 1,   BAD↓, 2,   BAD↑, 5,   Bak↑, 5,   BAX↑, 39,   BAX⇅, 1,   Bax:Bcl2↑, 2,   Bcl-2↓, 63,   Bcl-2↑, 1,   cl‑Bcl-2↓, 1,   Bcl-xL↓, 33,   Bcl-xL↑, 1,   BID↓, 1,   BID↑, 7,   p‑BID↓, 1,   cl‑BID↑, 1,   BIM↑, 7,   BNIP3↑, 1,   BOK↑, 2,   Casp↑, 4,   Casp↝, 1,   cl‑Casp12↑, 1,   Casp2↑, 4,   Casp3↓, 1,   Casp3↑, 57,   cl‑Casp3↑, 8,   Casp7↑, 5,   cl‑Casp7↑, 1,   Casp8↑, 13,   cl‑Casp8↑, 3,   proCasp8↑, 2,   pro‑Casp8↑, 1,   Casp9↑, 37,   cl‑Casp9↑, 6,   cFLIP↓, 2,   CSR1↑, 1,   Cyt‑c↑, 28,   Diablo↑, 6,   DR5↑, 13,   FADD↑, 5,   Fas↓, 1,   Fas↑, 12,   FasL↑, 5,   Ferroptosis↑, 1,   GSDME↑, 1,   HEY1↓, 1,   IAP1↓, 4,   IAP2/BIRC3↓, 2,   IAP2/BIRC3↑, 1,   iNOS↓, 7,   Mcl-1?, 1,   Mcl-1↓, 106,   Mcl-1↑, 2,   p‑Mcl-1↓, 1,   cl‑Mcl-1↑, 1,   MDM2↓, 3,   MDM2↑, 1,   MOMP↓, 1,   NAIP↓, 2,   NOXA↑, 3,   p38↓, 3,   p38↑, 8,   p‑p38↓, 1,   p‑p38↑, 1,   PUMA↑, 4,   Pyro↑, 2,   survivin↓, 36,   TRAIL↑, 3,   TumCD↓, 1,   TumCD↑, 5,   XIAP↓, 19,   XIAP↝, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 38,   Akt↑, 4,   p‑Akt↓, 12,   AKT1↓, 1,   Akt2↓, 1,   CK2↓, 2,   cMET↓, 1,   cSrc↓, 1,   EF-1α↓, 1,   EGFR↓, 12,   EphB4↓, 1,   ERK↓, 11,   p‑ERK↓, 5,   p‑ERK↑, 1,   FLT4↓, 1,   HER2/EBBR2↓, 3,   IGF-1R↓, 4,   IKKα↓, 3,   IκB↓, 1,   IκB↑, 1,   p‑IκB↓, 1,   JAK↓, 2,   JAK1↓, 2,   JAK2↓, 7,   JNK↓, 3,   JNK↑, 10,   p‑JNK↓, 1,   p‑JNK↑, 1,   MAPK?, 1,   MAPK↓, 7,   MAPK↑, 4,   p‑MAPK↑, 1,   MEK↓, 3,   p‑MEK↑, 1,   mTOR↓, 19,   p‑mTOR↓, 5,   p‑p42↓, 1,   P70S6K↓, 1,   p‑P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 27,   p‑PI3K↓, 2,   PI3K/Akt↓, 1,   PIAS-3↑, 2,   PKA↓, 1,   PKCδ↓, 3,   PTEN↓, 1,   PTEN↑, 8,   PTPN6↑, 1,   Raf↓, 1,   e-Raf↓, 1,   c-Raf↓, 1,   RAS↓, 2,   RTK-RAS↓, 1,   SHP1↑, 2,   Sp1/3/4↓, 4,   Src↓, 4,   Src↑, 1,   STAT↓, 1,   STAT3↓, 25,   STAT3↑, 1,   p‑STAT3↓, 4,   STAT5↓, 1,   STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 2,   ATF4↓, 1,   ATF4↑, 4,   CBP↓, 1,   cJun↓, 3,   cJun↑, 1,   cMyc↓, 10,   DNMT1↓, 3,   DNMT3A↓, 1,   DNMTs↓, 1,   EZH2↓, 2,   FOXM1↓, 2,   FOXO↑, 2,   FOXO3↑, 3,   H3↑, 2,   H4↑, 1,   HATs↓, 3,   HATs↑, 1,   HDAC↓, 5,   HDAC1↓, 1,   HDAC10↑, 1,   HDAC4↓, 1,   HES1↓, 1,   miR-200c↑, 1,   miR-205↑, 1,   miR-21↓, 2,   miR-29b↓, 1,   miR-34a↑, 2,   miR-34b-5p↑, 1,   miR-384↑, 1,   Myc↓, 3,   OCT4↓, 3,   other↓, 2,   other↝, 2,   SOX2↓, 1,   SOX4↓, 1,   SPP1↓, 1,   SUV39H↓, 1,   TCF-4↓, 1,   tumCV↓, 14,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↑, 5,   cl‑CHOP/DDIT3↑, 1,   eIF2α↓, 1,   eIF2α↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 11,   GRP78/BiP↑, 4,   Hsc70↓, 1,   HSF1↓, 1,   HSP27↓, 1,   HSP27↝, 1,   HSP70/HSPA5↓, 4,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 6,   IRE1↑, 2,   PERK↑, 2,   UPR↑, 2,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   ATG7↑, 2,   Beclin-1/ATG6↑, 4,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 3,   p62↓, 1,   PARK2↑, 1,   TumAuto↑, 3,   TumAuto⇅, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↓, 1,   ATM↑, 1,   p‑BRCA1↑, 1,   DFF45↓, 1,   DNA-PK↓, 1,   DNAdam↓, 1,   DNAdam↑, 8,   mt-DNAdam↑, 1,   DNArepair↓, 1,   ERCC1↓, 2,   ERCC4/XPF↓, 1,   hTERT/TERT↓, 2,   Ku70/XRCC6↓, 1,   MGMT↓, 1,   p16↑, 3,   P53?, 1,   P53↓, 2,   P53↑, 21,   PARP↓, 1,   PARP↑, 8,   PARP↝, 1,   cl‑PARP↑, 29,   PARP1↓, 1,   PCNA↓, 5,   SIRT6↑, 1,   Telomerase↓, 4,   TOP1↓, 3,   TOP2↓, 1,   TP53↑, 1,   UHRF1↓, 1,   γH2AX↑, 2,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 4,   CDK2↓, 14,   p‑CDK2↓, 1,   CDK4↓, 14,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 9,   CDK8↓, 1,   CHK1↓, 1,   Chk2↓, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 3,   CycB/CCNB1↓, 7,   cycD1/CCND1↓, 29,   p‑cycD1/CCND1↓, 1,   CycD3↓, 1,   cycE/CCNE↓, 10,   cycE1↓, 1,   E2Fs↓, 1,   Ki-67↓, 8,   mitA↑, 1,   P21?, 1,   P21↓, 2,   P21↑, 12,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 8,   pRB↑, 1,   p‑RB1↓, 3,   Securin↓, 1,   TumCCA↑, 37,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH1A1↓, 2,   CD133↓, 1,   cFos↓, 3,   CSCs↓, 7,   Diff↑, 1,   FBXW7↝, 1,   Gli1↓, 1,   HH↓, 1,   IGF-1↓, 2,   p‑IGF-1↓, 1,   IGFBP1↑, 1,   Ki-67↓, 8,   mTORC1↓, 1,   Nanog↓, 4,   Nestin↓, 1,   NOTCH↓, 7,   NOTCH1↓, 2,   NOTCH1↑, 1,   NOTCH3↓, 1,   p300↓, 1,   Shh↓, 1,   p‑STAT1↓, 1,   TumCG↓, 17,   TumCP?, 1,   TumCP↓, 29,   tyrosinase↓, 1,   Wnt?, 1,   Wnt↓, 13,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 2,   AP-1↓, 6,   AXL↓, 1,   BACH1↓, 1,   Ca+2↓, 3,   Ca+2↑, 6,   Ca+2↝, 1,   CAFs/TAFs↓, 1,   DLC1↑, 1,   E-cadherin↓, 1,   E-cadherin↑, 8,   EM↑, 1,   EMT↓, 18,   FAK↓, 6,   p‑FAK↓, 1,   Fibronectin↓, 4,   GLI2↓, 1,   GnT-V↝, 1,   heparanase↝, 1,   ITGA5↓, 1,   ITGB1↓, 1,   ITGB3↓, 1,   LAMs↓, 1,   MET↓, 1,   MMP-10↓, 1,   MMP1↓, 2,   MMP13↓, 1,   MMP16↓, 1,   MMP2↓, 22,   MMP3↓, 5,   MMP7↓, 6,   MMP9↓, 29,   MMP9↑, 1,   MMPs↓, 11,   MUC4↓, 1,   N-cadherin↓, 10,   NM23↑, 1,   p‑p44↓, 2,   PDGF↓, 1,   Rac1↓, 1,   Slug↓, 6,   p‑SMAD2↓, 1,   SMAD3↓, 2,   p‑SMAD3↓, 1,   SMAD4↓, 1,   p‑SMAD4↓, 1,   Snail?, 1,   Snail↓, 11,   TET1↑, 1,   TGF-β↓, 5,   TIMP1↑, 1,   TIMP2↑, 3,   TumCA↑, 1,   TumCI↓, 12,   TumCMig↓, 10,   TumMeta↓, 16,   Twist↓, 10,   uPA↓, 7,   Vim↓, 12,   Zeb1↓, 5,   ZEB2↓, 1,   α-tubulin↓, 1,   α-tubulin↑, 1,   β-catenin/ZEB1↓, 14,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 30,   Endoglin↑, 1,   eNOS↓, 1,   HIF-1↓, 2,   Hif1a↓, 20,   NO↓, 2,   VCAM-1↓, 1,   VEGF↓, 31,   VEGF↑, 1,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 6,  

Barriers & Transport(tgid=15) ⓘ

CLDN1↓, 1,   GLUT1↓, 3,   MMP↓, 20,   MMP↑, 1,   MPT↑, 2,   NHE1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD44↓, 2,   COX1↓, 1,   COX2/PTGS2↓, 22,   COX2/PTGS2↑, 1,   CXCL1↓, 1,   CXCR2↓, 1,   CXCR4↓, 7,   CXCR4↑, 1,   DR4↑, 3,   ICAM-1↓, 1,   IL1↓, 2,   IL10↓, 2,   IL12↓, 1,   IL1β↓, 4,   IL2↑, 1,   IL4↓, 1,   IL6↓, 9,   IL8↓, 1,   Inflam↓, 8,   M2 MC↓, 1,   mPGES-1↓, 1,   NF-kB?, 1,   NF-kB↓, 32,   NF-kB↑, 2,   NLRP3↑, 1,   p65↓, 4,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 1,   PGE2↓, 9,   SOCS-3↑, 1,   SOCS1↑, 1,   T-Cell↝, 1,   TCF↑, 1,   TLR4↓, 1,   TLR4↝, 1,   TNF-α↓, 8,   TNF-α↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

IM↓, 1,   PLC↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 5,   ER-α36↓, 1,   PPARα↓, 1,   cl‑PPARα↓, 1,   PPARγ↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 2,   BioAv↓, 9,   BioAv↑, 6,   BioAv↝, 1,   ChemoSen↑, 35,   CompStab↑, 1,   CompStab↝, 1,   CYP1A1↓, 1,   CYP1A1↑, 1,   CYP1B1↑, 1,   Dose?, 2,   Dose↓, 1,   Dose↑, 1,   Dose↝, 12,   Dose∅, 2,   eff↓, 9,   eff↑, 27,   Half-Life↓, 3,   Half-Life↝, 3,   MDR1↓, 1,   NAT↓, 1,   P-gp/ABCB1↓, 5,   RadioS↑, 9,   selectivity?, 1,   selectivity↑, 12,   Synergy↑, 29,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALP↓, 2,   AR↓, 5,   AST↓, 1,   p‑BRCA1↑, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 12,   EZH2↓, 2,   FOXM1↓, 2,   HEC1↓, 1,   HER2/EBBR2↓, 3,   hTERT/TERT↓, 2,   IL6↓, 9,   LDH↓, 3,   Myc↓, 3,   NOS2↓, 1,   PD-L1↓, 1,   TP53↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiTum↑, 3,   cardioP↑, 1,   chemoP?, 1,   chemoP↑, 4,   chemoPv↑, 6,   hepatoP↑, 1,   IMPDH1↓, 1,   IMPDH2↓, 1,   neuroP↑, 2,   NP/CIPN↓, 1,   ORR↑, 1,   OS↑, 1,   radioP↑, 2,   RenoP↑, 2,   toxicity↓, 5,   toxicity↝, 3,   toxicity∅, 1,   TumVol↓, 6,   TumW↓, 4,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,  
Total Targets: 581

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 9,   Catalase↑, 1,   GPx↑, 1,   GSH↑, 2,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   Keap1↝, 1,   MDA↓, 1,   NRF2↑, 2,   Prx↑, 1,   ROS↓, 9,   mt-ROS?, 1,   SOD↑, 1,   SOD2↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↑, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   ATP↑, 1,   glucose↓, 1,   LDHA↑, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Casp3?, 1,   Casp3↓, 1,   iNOS↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

PI3K↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

PARP1↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   MMP9↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   VCAM-1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   MMP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   COX2/PTGS2↑, 1,   IL18↓, 1,   IL1β↓, 1,   IL6↓, 1,   Inflam↓, 6,   Inflam↑, 1,   pol-M2 MC↑, 1,   NF-kB↓, 4,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 1,   BDNF↑, 1,   NGF↑, 1,  

Protein Aggregation(tgid=19) ⓘ

p‑tau↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 8,   BioAv↑, 2,   BioAv↝, 3,   Half-Life↝, 1,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 2,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

antiAll↑, 2,   AntiArt↑, 1,   AntiCan↑, 2,   AntiDiabetic↑, 2,   antiPs↑, 2,   AntiTum↑, 1,   cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 1,   hepatoP↑, 4,   memory↑, 1,   neuroP↑, 8,   Obesity↓, 1,   Stroke↓, 1,   toxicity↓, 4,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 2,   AntiP↑, 1,   AntiViral↑, 2,   Bacteria↓, 2,   GutMicro↑, 1,  
Total Targets: 81

Scientific Paper Hit Count for: Mcl-1, myeloid cell leukemia 1
7 Gossypol/AT-101
6 Citric Acid
6 Fisetin
4 Curcumin
3 Artemisinin
3 Baicalein
3 Chemotherapy
3 Emodin
3 Gambogic Acid
3 Garcinol
3 Luteolin
3 Phenethyl isothiocyanate
3 Quercetin
3 Silymarin (Milk Thistle) silibinin
2 3-bromopyruvate
2 Alpha-Lipoic-Acid
2 Apigenin (mainly Parsley)
2 Cisplatin
2 chaetocin
2 Chrysin
2 Formononetin
2 Hibiscus sabdariffa
2 Honokiol
2 Morin
2 Nimbolide
2 Resveratrol
2 Thymoquinone
1 Silver-NanoParticles
1 Allyl isothiocyanate
1 Sorafenib (brand name Nexavar)
1 Ashwagandha(Withaferin A)
1 Berberine
1 Betulinic acid
1 Bufalin/Huachansu
1 Cat’s Claw
1 Celastrol
1 immunotherapy
1 Cucurbitacin
1 Docetaxel
1 methylseleninic acid
1 CUSP9
1 Electrical Pulses
1 Ellagic acid
1 EGCG (Epigallocatechin Gallate)
1 Ferulic acid
1 Fucoidan
1 Galloflavin
1 Paclitaxel/Taxol
1 carboplatin
1 HydroxyTyrosol
1 Isobavachalcone
1 isoorientin
1 Isovitexin
1 Kaempferol
1 Licochalcone A
1 Lemongrass Extract/Citral
1 Methylene blue
1 Photodynamic Therapy
1 Magnolol
1 Magnetic Fields
1 Mangiferin
1 Melatonin
1 Mushroom Shiitake, AHCC
1 Naringin
1 Oleuropein
1 Patchouli Oil (Pogostemon cablin)
1 Piperlongumine
1 Rauwolfia serpentina/Indian Snakeroot
1 Sulforaphane (mainly Broccoli)
1 Shikonin
1 Aflavin-3,3′-digallate
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:182  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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