GutMicro Cancer Research Results

GutMicro, Gut Microbiota: Click to Expand ⟱
Source:
Type:
Gut microbiome may affect responses to numerous forms of cancer therapy.
The gut microbiota plays a multifaceted role in cancer biology, influencing tumor development, progression, and patient prognosis. Dysbiosis and specific microbial populations have been linked to various cancers, with implications for patient outcomes. While the relationship between gut microbiota and cancer prognosis is an active area of research, it holds promise for the development of microbiome-based biomarkers and therapeutic strategies in oncology.


Scientific Papers found: Click to Expand⟱
6022- CGA,    Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *BP↓, *Dose↝, *ROS↓, *Fas↓, *HMG-CoA↓, *GutMicro↑,
6016- CGA,    Coffee Chlorogenic Acids Incorporation for Bioactivity Enhancement of Foods: A Review
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
antiOx↑, *Bacteria↓, AntiCan↑, *Inflam↓, *cardioP↑, *AntiDiabetic↑, *GutMicro↑, *eff↑, *eff↑, *ROS↓, *IronCh↑, *neuroP↑, *AChE↓, *BChE↓, *chemoPv↑, *BioAv⇅,
6011- CGA,    Chlorogenic Acid’s Role in Metabolic Health: Mechanisms and Therapeutic Potential
- Review, Nor, NA
*BioAv↓, *antiOx↑, *Inflam↓, *Bacteria↓, *hepatoP↑, *cardioP↑, *neuroP↑, *ROS↓, *NF-kB↓, *NRF2↑, *Obesity↓, *GutMicro↑, *AntiAg↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *OCLN↓, *VEGF↓, BioAv↝,
6045- CGA,  SeNPs,    A Flower-like Brain Targeted Selenium Nanocluster Lowers the Chlorogenic Acid Dose for Ameliorating Cognitive Impairment in APP/PS1 Mice
- in-vivo, AD, NA
*neuroP↑, *BioAv↑, *GutMicro↑, *BBB↑, *Aβ↓, *glucose↝,
6023- CGA,    Pharmacological advances of the chlorogenic acids family: current insights and future research directions
- Review, AD, NA - Review, Park, NA - Review, IBD, NA
*Aβ↓, *neuroP↑, *cardioP↑, *GastroP↑, *RenoP↑, *hepatoP↑, *Obesity↓, *Bacteria↓, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *GutMicro↑, *IBI↑, *MCT1↓, *NF-kB↓, *DNMT1↓,
4487- Chit,  PreB,    Unravelling the Role of Chitin and Chitosan in Prebiotic Activity and Correlation With Cancer: A Narrative Review
- Review, NA, NA
*GutMicro↑, Apoptosis↑, BAX↑, Bcl-2↓, *Inflam↓, AntiTum↑,
6079- CHL,    Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice
- in-vivo, Nor, NA
*eff↑, *GutMicro↑, *NF-kB↓, *MMPs↑, *TIMP1↓, *Inflam↓, *Dysb↓,
6094- CHOC,    Impact of Cocoa Products Intake on Plasma and Urine Metabolites: A Review of Targeted and Non-Targeted Studies in Humans
- Human, Nor, NA
*GutMicro↑, *BP↓, *AntiAg↑,
6101- Chol,    Effect of Choline Forms and Gut Microbiota Composition on Trimethylamine-N-Oxide Response in Healthy Men
- Human, Nor, NA
*TMAO↑, *Dose↝, *GutMicro↝, *TMAO∅,
6145- Cin,    Cinnamaldehyde microcapsules enhance bioavailability and regulate intestinal flora in mice
- in-vivo, Nor, NA
BioAv↑, GutMicro↑,
6164- Cin,    Advances in pharmacological effects and mechanism of action of cinnamaldehyde
- Review, Var, NA - Review, PSA, NA
*glucose↑, *cardioP↑, *Inflam↓, *lipid-P↓, GutMicro↑, TumCP↓, Apoptosis↑, TumCI↓, TumCMig↓, BAX↑, P53↑, Bcl-2↓, IAP1↓, PI3K↓, Akt↓, *ROS↓, *NRF2↑, *NF-kB↓, NF-kB↑,
6169- Cin,    Unlocking the Power of Cinnamon: A Detailed Review of Cinnamon Therapeutic Effects in Chronic Disease Management
- Review, Var, NA - Review, Diabetic, NA - Review, AD, NA - Review, IBD, NA
*neuroP↑, *AntiDiabetic↑, *tau↓, *Aβ↓, *antiOx↑, *Inflam↓, *ROS↓, *MDA↓, *GSH↓, *cardioP↑, *LDL↓, *HDL↑, *other↝, *TNF-α↓, *IL6↓, *MPO↓, *TLR4↓, *GutMicro↑, *lipid-P↓, *Wound Healing↑,
3890- Cin,    The Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases
- Review, NA, NA
*cardioP↑, *Inflam↓, *ROS↓, *lipid-P↓, *AntiAg↑, *angioG↑, *GutMicro↑, *ER Stress↓,
5798- CRMs,    Caloric restriction mimetics improve gut microbiota: a promising neurotherapeutics approach for managing age-related neurodegenerative disorders
- Review, Nor, NA - Review, AD, NA
*GutMicro↑, *neuroP↑, *eff↑, *Dose↝, *AMPK↑, *SIRT1↑, *mTOR↓, *NRF2↑, *p‑tau↓,
6216- CUR,    Role of Turmeric and Curcumin in Prevention and Treatment of Chronic Diseases: Lessons Learned from Clinical Trials
- Review, Var, NA
TumCG↓, angioG↓, EMT↓, TumCI↓, TumMeta↓, *GutMicro↑, *BioAv↓, *HO-1↑, *ROS↓, *COX2↓, *iNOS↓, PKCδ↓, EGFR↓, NF-kB↓, cJun↓, cFos↓, cMyc↓, Akt↓, PI3K↓, CDK4↓, *TNF-α↓, *CRP↓, *IL6↓, MMP9↓, VEGF↓, JAK↓, STAT↓, IL1↓, IL2↓, IL6↓, IL8↓, IL12↓, MCP1↓, Apoptosis↑, ER Stress↑, 5LO↓, XO↓, *NRF2↑, *HO-1↑, *AChE↓, *neuroP↑, *glucose↓, *GLUT2↑, *GLUT3↑, *GLUT4↑, *GlucoseCon↑, *AMPK↑, *BMD↑, *MDA↓, *eff↑, eff↑, P53↑, BAX↑, DNAdam↑, Bcl-2↓, CSCs↓, ALDH↓, CD133↑,
6223- CUR,    Curcumin Rewires the Tumor Metabolic Landscape: Mechanisms and Clinical Prospects
- Review, Var, NA
Ferroptosis↑, GutMicro↑, Akt↓, mTOR↓, NF-kB↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, TumCP↓, TumCI↓, TumMeta↓, AMPK↑, P53↑, NRF2↑, TumCCA↑, Apoptosis↑, Casp↑, GPx4↓, DNMTs↓, HDAC↓, VEGF↓, Imm↑, NK cell↑, Warburg↓, Hif1a↓, HK2↓, PKM2↓, LDHA↓, GLUT1↓, MCT1↓, AMPK↑, FASN↓, SCD1↓, GLS↓, Apoptosis↑, ETC↓, MMP↓, ROS↑, lipid-P↑, ChemoSen↑, PDK1↓, Beclin-1↓, ATP↓, Glycolysis↓, GlucoseCon↓, lactateProd↑, MMPs↓, GSH↓, G6PD↓, OXPHOS↓, SREBP2↓, COX2↓, AP-1↓, NADH↓, NRF2↑, HO-1↑, Iron↑, MDA↑, *ROS↓, *Inflam↓,
4673- CUR,    Curcumin and colorectal cancer: An update and current perspective on this natural medicine
- Review, CRC, NA
AntiCan↑, GutMicro↝,
3794- CUR,    Curcumin hybrid molecules for the treatment of Alzheimer's disease: Structure and pharmacological activities
- Review, AD, NA
*GSK‐3β↓, *CDK5↓, *p‑tau↓, *IronCh↑, *ROS↓, *HO-1↑, *SOD↑, *Catalase↑, *GSH↑, *TNF-α↓, *IL6↓, *IL12↓, *NRF2↑, *PPARγ↑, *IL4↑, *AChE↓, *Dose↝, *GutMicro↑,
6666- DFE,    The impact of date palm fruits and their component polyphenols, on gut microbial ecology, bacterial metabolites and colon cancer cell proliferation
- in-vitro, Colon, Caco-2
*Fibre↑, *Poly↑, *other↝, *QC↑, *Api↑, *Myr↑, *LT↑, TumCP↓, *GutMicro↑, *Inflam↓, *antiOx↑,
6663- DFE,    Nutraceuticals of Phoenix dactylifera L.: Physicochemistry, Nutritional Value and Therapeutic Potential
- Review, Nor, NA - Review, AD, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *AntiDiabetic↑, *AntiCan↑, *AntiArt↑, *neuroP↑, *hepatoP↑, *GastroP↑, *other↝, *cardioP↑, *cognitive↑, *ROS↓, *memory↑, *other↝, *SOD↑, *Catalase↑, *GSH↑, *GA↑, *Catechins↑, *FA↑, *QC↑, Api↑, *CA↑, *Imm↑, *Phen↑, *IL1β↓, *TGF-β↓, *COX1↓, *COX2↓, TumCP↓, Casp3↑, TumMeta↓, *GutMicro↑,
6710- dietF,    The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on fermented foods
- Review, Nor, NA
*other↝, *toxicity↓, *toxicity↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *Imm↑,
6717- dietF,    Fermented foods consumption, all-cause, and cause-specific mortality: a meta-analysis of prospective cohort studies
- Review, CardioV, NA
*Risk↓, *cardioP↑, *GutMicro↑, *OS↑, *BP↓,
6711- dietF,    Gut-microbiota-targeted diets modulate human immune status
- Trial, Nor, NA
*GutMicro↑, *Inflam↓, *Imm↑, *Obesity↓, *AntiDiabetic↑, *AntiCan↑, *cardioP↑, *IL6↓, *IL10↓, *IL12↓,
6715- dietF,    Are Fermented Foods Effective against Inflammatory Diseases?
- Review, Nor, NA
*Imm↑, *GastroP↑, *Inflam↓, AntiCan↑, *AntiBio↑, *hepatoP↑, *CD4+↑, *IFN-γ↓, *IL17↓, *GutMicro↑, *antiOx↑, *AST↓, *ALAT↓, *HDL↑, *LDL↓, *ROS↓, *lipid-P↓, *Inflam↓, *Aβ↓,
6716- dietF,    Current Research in Fermented Foods: Bridging Tradition and Science
- Review, Nor, NA
*GutMicro↑, *Inflam↓, *BP↓, *LDL↓, *HDL↑, *CRP↓, *IL6↓, *TNF-α↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *neuroP↑, *cognitive↑,
1844- dietFMD,    Unlocking the Potential: Caloric Restriction, Caloric Restriction Mimetics, and Their Impact on Cancer Prevention and Treatment
- Review, NA, NA
Risk↓, AMPK↑, Akt↓, mTOR↓, SIRT1↑, Hif1a↓, NRF2↓, SOD↑, ROS↑, IGF-1↓, p‑Akt↓, PI3K↑, GutMicro↑, OS↑, eff↝, ROS↑, TumCCA↑, *DNArepair↑, DNAdam↑,
1856- dietFMD,  immuno,    Targeting the Gut Microbiome to Improve Immunotherapy Outcomes: A Review
- Review, Var, NA
GutMicro↑,
1863- dietFMD,  Chemo,    Effect of fasting on cancer: A narrative review of scientific evidence
- Review, Var, NA
eff↑, ChemoSideEff↓, ChemoSen↑, Insulin↓, HDAC↓, IGF-1↓, STAT5↓, BG↓, MAPK↓, HO-1↓, ATG3↑, Beclin-1↑, p62↑, SIRT1↑, LAMP2↑, OXPHOS↑, ROS↑, P53↑, DNAdam↑, TumCD↑, ATP↑, Treg lymp↓, M2 MC↓, CD8+↑, Glycolysis↓, GutMicro↑, GutMicro↑, Warburg↓, Dose↝,
1850- dietFMD,    Fasting-mimicking diet remodels gut microbiota and suppresses colorectal cancer progression
- in-vivo, CRC, NA
TumCP↑, angioG↓, CD8+↑, GutMicro↑, eff↑,
2272- dietMet,    Methionine restriction - Association with redox homeostasis and implications on aging and diseases
- Review, Nor, NA
*OS↑, *mt-ROS↓, *H2S↑, *FGF21↑, *cognitive↑, *GutMicro↑, *IGF-1↓, *mTOR↓, *GSH↑, *SOD↑, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *GLUT4↑, *Glycolysis↑, *HK2↑, *PFK↑, *PKM2↑, *GlucoseCon↑, *ATF4↑, *PPARα↑, GSH↓, GSTs↑, ROS↑, *neuroP↑,
1894- dietMet,    Long term methionine restriction: Influence on gut microbiome and metabolic characteristics
- in-vivo, Nor, NA
*GutMicro↓, *OS↑, Weight↓, BG↓,
6363- DRE,    Therapeutic Potential of Dandelion (Taraxacum officinale) Root Extract in Colon Cancer: A Comprehensive Review
- in-vitro, CRC, NA
Apoptosis↑, *Inflam↓, TLR4↓, NF-kB↓, *GutMicro↑, mtDam↑, *ROS↓, Casp1↑, TNF-α↑, Bcl-2↓, PARP↓, MMP↓, Cyt‑c↓, Casp3↑, TumVol↓, COX2↓, iNOS↓, ROS↑, selectivity↑, TumCMig↓, TumCI↓, ER Stress↑, PERK↑, eIF2α↑, ATF4↑, CHOP↑, TumCCA↑, cycD1/CCND1↓, P21↓, P53↑, BioAv↝, Half-Life↝,
6804- EA,    Ellagic acid metabolism by human gut microbiota: consistent observation of three urolithin phenotypes in intervention trials, independent of food source, age, and health status
- Human, Nor, NA
*other?, *Risk↓, *GutMicro↝,
6783- EGCG,    Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *Bacteria↓, *AntiBio↑, *BioAv↓, *GutMicro↑,
6784- EGCG,    Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *cardioP↑, *neuroP↑, *GutMicro↑, *AntiBio↑, *ROS↓, *TNF-α↓, *IL6↓, TumCP↓, *LDL↓, *NO↓, *Obesity↓, *p‑tau↓, *Aβ↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *NLRP3↓, *mTOR↓, TumCCA↑, NRF2↓, Apoptosis↑, SIRT1↓, miR-25-5p↓, PARP↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, EMT↓, TumCI↓, TumCMig↓, TGF-β↓, Smad1↓, STAT3↓, VEGF↓, angioG↓, Imm↑, EGFR↓, *GutMicro↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *BioAv↑, *eff↑, *BioAv↑, eff↑, ChemoSen↑, *toxicity↝,
6825- EMD,    Advances in the pharmacological effects and molecular mechanisms of emodin in the treatment of metabolic diseases
- Review, Nor, NA
*Inflam↓, *AntiTum↑, *Bacteria↓, *Imm↑, *glucose↓, *RenoP↑, *TLR4↓, *MyD88↓, *NLRP3↓, *NF-kB↓, *PI3K↓, *mTOR↓, *GSK‐3β↓, *Hif1a↓, *VEGF↓, *GutMicro↑, *Obesity↓, *AntiDiabetic↑, *AMPK↑, *PPARγ↑, *PPARγ↓, *toxicity↝, *hepatoP↑, *AST↓, *ALAT↓,
6323- Eug,    Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
- Review, Var, NA - Review, Arthritis, NA
*AntiCan↑, *AntiDiabetic↑, *cardioP↑, *toxicity↝, *GutMicro↑, *neuroP↑, *BioAv⇅, *BioAv↝, *antiOx↑, *Inflam↑, *AntiArt↑, *TNF-α↓, *IL6↓, *IL10↓, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TAC↑, TumCMig↓, TumCI↓, Akt↑, FOXO3↑, Casp3↑, Casp9↑, P21↑, angioG↓, TumCI↓, Apoptosis↑, NF-kB↓, eff↑, eff↑, ChemoSen↑, NA↑, Casp3↑, Casp9↑, *AntiDiabetic↑, *glucose↓, *ROS↓, *Inflam↓, *MDA↓, *GSH↑, *BioAv↑,
1038- F,  immuno,    Fucoidan enhances the anti-tumor effect of anti-PD-1 immunotherapy by regulating gut microbiota.
- in-vivo, BC, NA
GutMicro↑, T-Cell↑, Treg lymp↓,
3778- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer’s Disease: A Narrative Review
- Review, AD, NA
*neuroP↑, *Aβ↓, *antiOx↑, *Inflam↓, *ROS↓, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK?, *hepatoP↑, *TLR4↓, *PPARγ↑, *NRF2↑, *Fenton↓, *IronCh↑, *MDA↓, *HO-1↑, *Bil↑, *GCLC↑, *GCLM↑, *NQO1↑, *GutMicro↑, *SOD↑, *Ca+2↓, *lipid-P↓, *PGE2↓,
3714- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK↓, *p38↓, *JNK↓, *IL6↓, *IL8↓, *hepatoP↑, *RenoP↑, *Catalase↑, *PPARγ↑, *ROS↓, *Fenton↓, *IronCh↑, *SOD↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ARE↑, *Bil↑, *radioP↑, *GCLC↑, *GCLM↑, *NQO1↑, *Half-Life↝, *GutMicro↑, *Aβ↓, *BDNF↑, *Ca+2↓, *lipid-P↓, *PGE2↓, *cognitive↑, *ChAT↑, *memory↑, *Dose↝, *toxicity↓,
3716- FA,    Ferulic Acid as a Protective Antioxidant of Human Intestinal Epithelial Cells
- in-vitro, IBD, NA - in-vivo, NA, NA
*antiOx↑, *Inflam↓, *ER Stress↓, *other↑, *angioG↑, *Hif1a↑, *VEGF↑, *NO↓, *SIRT1↑, *PERK↓, *ATF4↓, *CHOP↓, *GutMicro↑,
4030- FulvicA,    Therapeutic Potential of Fulvic Acid in Chronic Inflammatory Diseases and Diabetes
- Review, NA, NA
*Inflam↓, TNF-α↓, *COX2↓, *PGE2↓, *ROS↓, *GutMicro↑, *BioEnh↑, *BioEnh↑, *SOD↑, *Catalase↑, *GPx↑,
1773- GA,    Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action
- Review, Var, NA
antiOx↑, AntiCan↑, Inflam↑, GutMicro↑, BioAv↝, BioAv↓, BioAv↑, TumMeta↓,
2523- H2,    Prospects of molecular hydrogen in cancer prevention and treatment
- Review, Var, NA
ROS↓, TumCP↓, TumMeta↓, AntiTum↑, GutMicro↑, Inflam↓, OS↑, radioP↑, selectivity↑, SOD↑, IL1β↑, IL8↑, TNF-α↑, neuroP↑,
2521- H2,    Oxyhydrogen Gas: A Promising Therapeutic Approach for Lung, Breast and Colorectal Cancer
- Review, CRC, NA - Review, Lung, NA - Review, BC, NA
Inflam↑, ROS↓, ChemoSen↑, p‑PI3K↓, p‑Akt↓, QoL↑, GutMicro↑, chemoP↑, radioP↑, *NRF2↑, *Catalase↑, *GPx↑, *HO-1↑, *SOD↑, *TNF-α↓, *IL4↓, *IL6↓, ChemoSen↑, Appetite↑, cognitive↑, Pain↓, Sleep↑, other?,
3772- H2,    Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *Inflam↓, *ROS↓, *GutMicro↑, *TNF-α↓, *IL6↓, *IL1β↓, *IL10↓, *Catalase↑, *GSH↑,
1791- LEC,    Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention
- Review, Nor, NA
*BioEnh↑, *antiOx↑, *BioEnh↑, *LDL↓, *HDL∅, *Obesity↓, eff↑, GutMicro↝,
1793- LEC,    Unmasking Sunflower Lecithin: Does Science Support the Claims?
- Review, NA, NA
BioEnh↑, memory↑, Inflam↓, GutMicro↑, antiOx↑,
2921- LT,    Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies
- Review, Nor, NA
*hepatoP↑, *AMPK↑, *SIRT1↑, *ROS↓, STAT3↓, TNF-α↓, NF-kB↓, *IL2↓, *IFN-γ↓, *GSH↑, *SREBP1↓, *ZO-1↑, *TLR4↓, BAX↑, Bcl-2↓, XIAP↓, Fas↑, Casp8↑, Beclin-1↑, *TXNIP↓, *Casp1↓, *IL1β↓, *IL18↓, *NLRP3↓, *MDA↓, *SOD↑, *NRF2↑, *ER Stress↓, *ALAT↓, *AST↓, *iNOS↓, *IL6↓, *HO-1↑, *NQO1↑, *PPARα↑, *ATF4↓, *CHOP↓, *Inflam↓, *antiOx↑, *GutMicro↑,
2916- LT,    Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies
- Review, Var, NA - Review, AD, NA - Review, Park, NA
proCasp9↓, CDC2↓, CycB/CCNB1↓, Casp9↑, Casp3↑, Cyt‑c↑, cycA1/CCNA1↑, CDK2↓, APAF1↑, TumCCA↑, P53↑, BAX↑, VEGF↓, Bcl-2↓, Apoptosis↑, p‑Akt↓, p‑EGFR↓, p‑ERK↓, p‑STAT3↓, cardioP↑, Catalase↓, SOD↓, *BioAv↓, *antiOx↑, *ROS↓, *NO↓, *GSTs↑, *GSR↑, *SOD↑, *Catalase↑, *lipid-P↓, PI3K↓, Akt↓, CDK2↓, BNIP3↑, hTERT/TERT↓, DR5↑, Beclin-1↑, TNF-α↓, NF-kB↓, IL1↓, IL6↓, EMT↓, FAK↓, E-cadherin↑, MDM2↓, NOTCH↓, MAPK↑, Vim↓, N-cadherin↓, Snail↓, MMP2↓, Twist↓, MMP9↓, ROS↑, MMP↓, *AChE↓, *MMP↑, *Aβ↓, *neuroP↑, Trx1↑, ROS↓, *NRF2↑, NRF2↓, *BBB↑, ChemoSen↑, GutMicro↑,

Showing Research Papers: 51 to 100 of 154
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 154

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   Catalase↓, 1,   Ferroptosis↑, 1,   GPx4↓, 1,   GSH↓, 2,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   Iron↑, 1,   lipid-P↑, 1,   MDA↑, 1,   NADH↓, 1,   NRF2↓, 3,   NRF2↑, 2,   OXPHOS↓, 1,   OXPHOS↑, 1,   ROS↓, 3,   ROS↑, 7,   SOD↓, 1,   SOD↑, 2,   Trx1↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   ATP↑, 1,   CDC2↓, 1,   ETC↓, 1,   Insulin↓, 1,   MMP↓, 3,   mtDam↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 3,   cMyc↓, 1,   FASN↓, 1,   G6PD↓, 1,   GLS↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 2,   HK2↓, 1,   lactateProd↑, 1,   LDHA↓, 1,   PDK1↓, 1,   PKM2↓, 1,   SCD1↓, 1,   SIRT1↓, 1,   SIRT1↑, 2,   SREBP2↓, 1,   Warburg↓, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 5,   Akt↑, 1,   p‑Akt↓, 3,   APAF1↑, 1,   Apoptosis↑, 9,   BAX↑, 5,   Bcl-2↓, 6,   Casp↑, 1,   Casp1↑, 1,   Casp3↑, 6,   Casp8↑, 1,   Casp9↑, 4,   proCasp9↓, 1,   Cyt‑c↓, 1,   Cyt‑c↑, 1,   DR5↑, 1,   Fas↑, 1,   Ferroptosis↑, 1,   hTERT/TERT↓, 1,   IAP1↓, 1,   iNOS↓, 1,   MAPK↓, 1,   MAPK↑, 1,   MCT1↓, 1,   MDM2↓, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

miR-25-5p↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 1,   other?, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP↑, 1,   eIF2α↑, 1,   ER Stress↑, 3,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↑, 1,   Beclin-1↓, 1,   Beclin-1↑, 3,   BNIP3↑, 1,   LAMP2↑, 1,   p62↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 3,   DNMTs↓, 1,   P53↑, 6,   PARP↓, 1,   PARP↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 2,   CDK4↓, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   P21↓, 1,   P21↑, 1,   TumCCA↑, 5,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   CD133↑, 1,   cFos↓, 1,   CSCs↓, 1,   EMT↓, 3,   p‑ERK↓, 1,   FOXO3↑, 1,   HDAC↓, 2,   IGF-1↓, 2,   mTOR↓, 2,   NOTCH↓, 1,   PI3K↓, 3,   PI3K↑, 1,   p‑PI3K↓, 1,   STAT↓, 1,   STAT3↓, 3,   p‑STAT3↓, 1,   STAT5↓, 1,   TumCG↓, 1,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AP-1↓, 1,   E-cadherin↑, 1,   FAK↓, 1,   MMP2↓, 1,   MMP9↓, 2,   MMPs↓, 1,   N-cadherin↓, 1,   PKCδ↓, 1,   Smad1↓, 1,   Snail↓, 1,   TGF-β↓, 1,   Treg lymp↓, 2,   TumCI↓, 7,   TumCMig↓, 4,   TumCP↓, 6,   TumCP↑, 1,   TumMeta↓, 5,   Twist↓, 1,   Vim↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   ATF4↑, 1,   EGFR↓, 2,   p‑EGFR↓, 1,   Hif1a↓, 2,   VEGF↓, 4,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 2,   IL1↓, 2,   IL12↓, 1,   IL1β↑, 1,   IL2↓, 1,   IL6↓, 2,   IL8↓, 1,   IL8↑, 1,   Imm↑, 2,   Inflam↓, 2,   Inflam↑, 2,   JAK↓, 1,   M2 MC↓, 1,   MCP1↓, 1,   NF-kB↓, 6,   NF-kB↑, 1,   NK cell↑, 1,   T-Cell↑, 1,   TLR4↓, 1,   TNF-α↓, 3,   TNF-α↑, 2,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 2,   BioAv↝, 3,   BioEnh↑, 1,   ChemoSen↑, 7,   Dose↝, 1,   eff↑, 7,   eff↝, 1,   Half-Life↝, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

BG↓, 2,   EGFR↓, 2,   p‑EGFR↓, 1,   GutMicro↑, 14,   GutMicro↝, 2,   hTERT/TERT↓, 1,   IL6↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 4,   AntiTum↑, 2,   Appetite↑, 1,   cardioP↑, 1,   chemoP↑, 1,   ChemoSideEff↓, 1,   cognitive↑, 1,   memory↑, 1,   neuroP↑, 1,   OS↑, 2,   Pain↓, 1,   QoL↑, 1,   radioP↑, 2,   Risk↓, 1,   Sleep↑, 1,   TumVol↓, 1,   Weight↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,  
Total Targets: 206

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 2,   AntiBio↑, 4,   Dysb↓, 1,   TMAO↑, 1,   TMAO∅, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 15,   ARE↑, 1,   Bil↑, 2,   Catalase↑, 9,   Fenton↓, 2,   GCLC↑, 2,   GCLM↑, 2,   GPx↑, 4,   GSH↓, 1,   GSH↑, 7,   GSR↑, 1,   GSTs↑, 1,   HDL↑, 3,   HDL∅, 1,   HO-1↑, 8,   lipid-P↓, 8,   MDA↓, 8,   MPO↓, 1,   NQO1↑, 4,   NRF2↑, 12,   ROS↓, 21,   mt-ROS↓, 1,   SOD↑, 10,   TAC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 4,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 3,   AMPK↑, 4,   FGF21↑, 1,   glucose↓, 3,   glucose↑, 1,   glucose↝, 1,   GlucoseCon↑, 2,   GLUT2↑, 1,   Glycolysis↑, 1,   H2S↑, 1,   HK2↑, 1,   HMG-CoA↓, 1,   LDL↓, 5,   PFK↑, 1,   PKM2↑, 1,   PPARα↑, 2,   PPARγ↓, 1,   PPARγ↑, 4,   SIRT1↑, 3,   SREBP1↓, 1,  

Cell Death(tgid=5) ⓘ

Casp1↓, 1,   Fas↓, 1,   iNOS↓, 4,   JNK↓, 1,   p‑MAPK?, 1,   p‑MAPK↓, 1,   MCT1↓, 1,   p38↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other?, 1,   other↑, 1,   other↝, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP↓, 2,   ER Stress↓, 3,   PERK↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNArepair↑, 1,   DNMT1↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↓, 2,   IGF-1↓, 1,   mTOR↓, 4,   PI3K↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 3,   Ca+2↓, 2,   CDK5↓, 1,   MMPs↑, 1,   TGF-β↓, 1,   TIMP1↓, 1,   TXNIP↓, 1,   VCAM-1↓, 2,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 2,   ATF4↓, 2,   ATF4↑, 1,   Hif1a↓, 1,   Hif1a↑, 1,   NO↓, 3,   VEGF↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   GastroP↑, 3,   GLUT3↑, 1,   GLUT4↑, 2,   IBI↑, 1,   OCLN↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX1↓, 1,   COX2↓, 5,   CRP↓, 2,   ICAM-1↓, 2,   IFN-γ↓, 2,   IL10↓, 3,   IL12↓, 2,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 5,   IL2↓, 1,   IL4↓, 1,   IL4↑, 1,   IL6↓, 11,   IL8↓, 1,   Imm↑, 5,   Inflam↓, 26,   Inflam↑, 1,   MyD88↓, 1,   NF-kB↓, 7,   PGE2↓, 3,   TLR4↓, 4,   TNF-α↓, 10,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 4,   BChE↓, 1,   BDNF↑, 1,   ChAT↑, 1,   tau↓, 1,   p‑tau↓, 3,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 9,   NLRP3↓, 6,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 5,   BioAv↑, 7,   BioAv⇅, 2,   BioAv↝, 1,   BioEnh↑, 4,   Dose↝, 5,   eff↑, 6,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   AST↓, 3,   Bil↑, 2,   BMD↑, 1,   BP↓, 4,   CRP↓, 2,   GutMicro↓, 1,   GutMicro↑, 34,   GutMicro↝, 2,   IL6↓, 11,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 5,   AntiDiabetic↑, 11,   AntiTum↑, 1,   cardioP↑, 14,   chemoPv↑, 1,   cognitive↑, 5,   hepatoP↑, 8,   memory↑, 2,   neuroP↑, 15,   Obesity↓, 9,   OS↑, 3,   radioP↑, 1,   RenoP↑, 3,   Risk↓, 2,   toxicity↓, 3,   toxicity↝, 3,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   Bacteria↓, 6,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   CA↑, 1,   Catechins↑, 1,   FA↑, 1,   Fibre↑, 1,   GA↑, 1,   LT↑, 1,   Myr↑, 1,   Phen↑, 1,   Poly↑, 1,   QC↑, 2,  
Total Targets: 174

Scientific Paper Hit Count for: GutMicro, Gut Microbiota
8 Butyrate
8 Selenium NanoParticles
7 immunotherapy
6 probiotics
6 Urolithin
5 Chlorogenic acid
5 Curcumin
5 diet Fermented Foods
4 Silver-NanoParticles
4 Akkermansia
4 Bifidobacterium
4 Cinnamon
4 diet FMD Fasting Mimicking Diet
4 Rosmarinic acid
4 Selenite (Sodium)
3 Allicin (mainly Garlic)
3 beta-glucans
3 Berberine
3 Capsaicin
3 Carvacrol
3 Ferulic acid
3 Hydrogen Gas
3 Pterostilbene
2 Anthocyanins
2 Astaxanthin
2 Baicalein
2 Vitamin B3,Niacin
2 chitosan
2 Date Fruit Extract
2 Chemotherapy
2 diet Methionine-Restricted Diet
2 EGCG (Epigallocatechin Gallate)
2 Lecithin
2 Luteolin
2 Naringin
2 Phenylbutyrate
2 Resveratrol
2 Sulforaphane (mainly Broccoli)
2 Silymarin (Milk Thistle) silibinin
2 Taurine
2 Thymol-Thymus vulgaris
1 1,8-Cineole
1 5-Hydroxytryptophan
1 Alpha-Lipoic-Acid
1 Aspirin
1 Atorvastatin
1 Aloe anthraquinones
1 Radiotherapy/Radiation
1 Baicalin
1 Boron
1 Boswellia (frankincense)
1 Bruteridin(bergamot juice)
1 Paclitaxel
1 Centella asiatica / Gotu kola → asiaticoside
1 Prebiotic
1 Chlorophyllin
1 Chocolate
1 Choline
1 Calorie Restriction Mimetics
1 Dandelion Root
1 Ellagic acid
1 Emodin
1 Eugenol
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Gallic acid
1 Lycopene
1 Magnolol
1 Magnetic Fields
1 nicotinamide adenine dinucleotide
1 Nimbolide
1 Oleocanthal
1 Quercetin
1 Shikonin
1 Spermidine
1 Aflavin-3,3′-digallate
1 Thyme
1 Turmerones
1 Ursolic acid
1 Vitamin D3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:350  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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