uPA Cancer Research Results

uPA, Urokinase plasminogen activator: Click to Expand ⟱
Source:
Type:
uPA (urokinase plasminogen activator) is a serine protease that plays a crucial role in the conversion of plasminogen to plasmin, an enzyme responsible for degrading various components of the extracellular matrix (ECM). This activity is central to processes such as tissue remodeling, cell migration, and angiogenesis. In the context of cancer, uPA facilitates tumor invasion and metastasis by promoting ECM degradation, while its interaction with its receptor (uPAR) and inhibitors (such as PAI-1) forms a regulatory axis that is frequently dysregulated in malignancies.

Patients with higher pretreatment serum uPA (≥1 ng/ml) had significantly shorter OS.

Elevated uPA expression has been observed in a broad range of cancers, including breast, colorectal, lung, and prostate cancers. These high levels are often indicative of increased proteolytic activity within the tumor microenvironment.
Tumors with aggressive behavior often exhibit upregulation of uPA, along with its receptor uPAR. This upregulation enhances plasmin generation and leads to an environment conducive to invasion and metastasis.

Elevated uPA levels in tumor tissues have been strongly associated with poor clinical outcomes. High uPA expression is correlated with increased risk of metastasis, higher likelihood of recurrence, and reduced overall survival in several cancer types.
Scientific Papers found: Click to Expand⟱
85- QC,    Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3)
- in-vitro, Pca, PC3
uPA↓, uPAR↓, EGFR↓, NRAS↓, Jun↓, NF-kB↓, β-catenin/ZEB1↓, p38↑, MAPK↑, cJun↓, cFos↓, Raf↓, TumCI↓, TumCMig↓,
2988- RES,    The Antimetastatic Effects of Resveratrol on Hepatocellular Carcinoma through the Downregulation of a Metastasis-Associated Protease by SP-1 Modulation
- in-vitro, HCC, HUH7
TumCMig↓, TumCI↓, uPA↓, Sp1/3/4↓,
3288- SIL,    Silymarin in cancer therapy: Mechanisms of action, protective roles in chemotherapy-induced toxicity, and nanoformulations
- Review, Var, NA
Inflam↓, lipid-P↓, TumMeta↓, angioG↓, chemoP↑, EMT↓, HDAC↓, HATs↑, MMPs↓, uPA↓, PI3K↓, Akt↓, VEGF↓, CD31/PECAM-1↓, Hif1a↓, VEGFR2/KDR/Flk1↓, Raf↓, MEK↓, ERK↓, BIM↓, BAX↑, Bcl-2↓, Bcl-xL↓, Casp↑, MAPK↓, P53↑, LC3II↑, mTOR↓, YAP/TEAD↓, *BioAv↓, MMP↓, Cyt‑c↑, PCNA↓, cMyc↓, cycD1/CCND1↓, β-catenin/ZEB1↓, survivin↓, APAF1↑, Casp3↑, MDSCs↓, IL10↓, IL2↑, IFN-γ↑, hepatoP↑, cardioP↑, GSH↑, neuroP↑,
3282- SIL,    Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions
- Review, Var, NA
hepatoP↑, AntiCan↑, TumCMig↓, Hif1a↓, selectivity↑, toxicity∅, *antiOx↑, *Inflam↓, TumCCA↑, P21↑, CDK4↓, NF-kB↓, ERK↓, PSA↓, TumCG↓, p27/CDKN1B↑, COX2/PTGS2↓, IL1↓, VEGF↓, IGFBP3↑, AR↓, STAT3↓, Telomerase↓, Cyt‑c↑, Casp↑, eff↝, HDAC↓, HATs↑, Zeb1↓, E-cadherin↑, miR-203↑, NHE1↓, MMP2↓, MMP9↓, PGE2↓, Vim↓, Wnt↓, angioG↓, VEGF↓, *TIMP1↓, EMT↓, TGF-β↓, CD44↓, EGFR↓, PDGF↓, *IL8↓, SREBP1/SREBF1↓, MMP↓, ATP↓, uPA↓, PD-L1↓, NOTCH↓, *SIRT1↑, SIRT1↓, CA↓, Ca+2↑, chemoP↑, cardioP↑, Dose↝, Half-Life↝, BioAv↓, BioAv↓, BioAv↓, toxicity↝, Half-Life↓, ROS↓, FAK↓,
3332- SIL,    Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2
- in-vitro, Lung, A549
*antiOx↑, *hepatoP↑, MMP2↓, uPA↓, TIMP2↑,
2197- SK,    Shikonin derivatives for cancer prevention and therapy
- Review, Var, NA
ROS↑, Ca+2↑, BAX↑, Bcl-2↓, MMP9↓, NF-kB↓, PKM2↓, Hif1a↓, NRF2↓, P53↑, DNMT1↓, MDR1↓, COX2/PTGS2↓, VEGF↓, EMT↓, MMP7↓, MMP13↓, uPA↓, RIP1↑, RIP3↑, Casp3↑, Casp7↑, Casp9↑, P21↓, DFF45↓, TRAIL↑, PTEN↑, mTOR↓, AR↓, FAK↓, Src↓, Myc↓, RadioS↑,

Showing Research Papers: 51 to 56 of 56
Prev Page 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 56

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Ceru↓, 1,   GPx4↓, 2,   GSH↓, 1,   GSH↑, 2,   GSR↑, 1,   GSTs↓, 1,   H2O2↑, 1,   HO-1↑, 5,   Iron↑, 1,   lipid-P↓, 2,   lipid-P↑, 3,   MDA↓, 1,   MDA↑, 1,   NQO1↑, 1,   NRF2↓, 4,   NRF2↑, 6,   p‑NRF2↓, 1,   ROS↓, 10,   ROS↑, 32,   i-ROS↑, 1,   mt-ROS↑, 1,   SOD↓, 1,   SOD↑, 1,   Trx1↓, 1,   TrxR↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   CDC2↓, 4,   CDC25↓, 8,   EGF↓, 3,   mitResp↓, 1,   MKK7↓, 1,   mtDam↑, 2,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   ACC↑, 2,   AMPK↑, 6,   ATP↓, 2,   mt-ATP↓, 1,   GlucoseCon↓, 1,   GlutMet↓, 1,   Glycolysis↓, 5,   GSK‐3β↓, 1,   GSK‐3β↑, 2,   HK2↓, 1,   lactateProd↓, 2,   LDHA↓, 2,   NADPH↓, 1,   NADPH↑, 2,   PCK1↓, 1,   PDK1 / PDPK1↓, 2,   PDK3↑, 1,   PKM2↓, 2,   SIRT1↓, 1,   SREBP1/SREBF1↓, 1,   TCA↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 2,   APAF1↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 13,   ASK1↑, 1,   BAD↑, 4,   Bak↑, 3,   BAX↑, 20,   BAX⇅, 1,   Bax:Bcl2↑, 2,   Bcl-2↓, 19,   Bcl-xL↓, 8,   BID↑, 2,   BIM↓, 1,   BIM↑, 5,   Casp↑, 6,   cl‑Casp↑, 1,   Casp12↑, 1,   Casp2↑, 1,   Casp3↓, 4,   Casp3↑, 19,   cl‑Casp3↑, 3,   Casp6↑, 1,   Casp7↑, 2,   Casp8↑, 10,   cl‑Casp8↑, 1,   Casp9↑, 18,   cl‑Casp9↑, 3,   cFLIP↓, 1,   Cyt‑c↑, 26,   Diablo↑, 7,   DR5↑, 8,   Endon↑, 1,   FADD↑, 1,   Fas↑, 6,   FasL↑, 3,   FasL⇅, 1,   Ferroptosis↑, 2,   HEY1↓, 1,   IAP1↓, 2,   IAP2/BIRC3↓, 2,   iNOS↓, 3,   Mcl-1↓, 7,   MDM2↓, 3,   MDM2↑, 1,   MOMP↑, 1,   p38↓, 3,   p38↑, 8,   p‑p38↓, 1,   PUMA↓, 1,   RIP1↑, 1,   RIP3↑, 1,   survivin↓, 9,   TRAIL↑, 2,   TRAILR↑, 2,   TumCD↑, 1,   XIAP↓, 5,   YAP/TEAD↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 26,   p‑Akt↓, 3,   CK2↓, 1,   cMET↓, 1,   EGFR↓, 15,   p‑EGFR↓, 1,   ERK↓, 14,   ERK↑, 1,   p‑ERK↓, 3,   FGFR1↓, 1,   HER2/EBBR2↓, 4,   HGF/c-Met↓, 1,   IGFR↓, 1,   IKKα↓, 2,   p‑IKKα↓, 1,   JAK1↓, 1,   JAK2↓, 2,   JNK↓, 3,   JNK↑, 6,   MAPK↓, 11,   MAPK↑, 5,   MEK↓, 4,   p‑MEK↓, 1,   mTOR↓, 17,   p‑mTOR↓, 2,   mTORC2↓, 3,   NRAS↓, 1,   p70S6↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 21,   PKCδ↓, 5,   PTEN↑, 11,   Raf↓, 5,   RAS↓, 6,   RET↓, 1,   p‑S6K↓, 1,   Sp1/3/4↓, 2,   Src↓, 1,   STAT3↓, 12,   p‑STAT3↓, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↓, 1,   ATF4↑, 4,   cJun↓, 8,   cJun↑, 1,   cMyc↓, 9,   DNMT1↓, 1,   DNMTs↓, 3,   EZH2↓, 1,   FOXM1↓, 2,   FOXO↑, 1,   FOXO1↑, 1,   FOXO3↓, 1,   FOXO3↑, 4,   FOXO4↑, 1,   H3↑, 1,   p‑H3↓, 1,   ac‑H3↑, 1,   ac‑H4↑, 1,   HATs↓, 1,   HATs↑, 2,   HDAC↓, 6,   HDAC1↓, 1,   HDAC3↓, 1,   HES1↓, 1,   miR-203↑, 1,   miR-21↓, 1,   miR-21↑, 1,   miR-34a↑, 1,   MTA2↓, 1,   Myc↓, 2,   n-MYC↓, 1,   OCT4↓, 1,   other↓, 1,   other↝, 1,   SOX2↓, 3,   SOX4↓, 1,   TCF-4↓, 2,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 6,   eIF2α↓, 1,   ER Stress↓, 1,   ER Stress↑, 9,   GRP78/BiP↑, 6,   HSF1↓, 1,   HSP27↓, 2,   HSP70/HSPA5↓, 5,   HSP90↓, 2,   HSPs↓, 1,   IRE1↑, 3,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   Beclin-1/ATG6↑, 5,   LC3B-II↑, 2,   LC3II↑, 4,   LC3s↑, 1,   p62↓, 2,   TumAuto↓, 1,   TumAuto↑, 5,  

DNA Damage & Repair(tgid=10) ⓘ

ATM?, 1,   ATM↑, 2,   DFF45↓, 1,   DNAdam↑, 8,   p16↑, 2,   P53↑, 17,   PARP↓, 1,   PARP↑, 3,   cl‑PARP↑, 10,   PARP1↑, 1,   PCNA↓, 8,   Telomerase↓, 5,   TOP1↓, 2,   TOP2↓, 3,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 5,   CDK2↓, 15,   CDK2↑, 1,   CDK4↓, 18,   CDK6↓, 6,   CDKN1C/p57↓, 1,   CHK1↓, 1,   CHK1↑, 1,   Chk2↓, 1,   Chk2↑, 1,   cycA1/CCNA1↓, 3,   CycB/CCNB1↓, 5,   cycD1/CCND1↓, 17,   CycD3↓, 1,   cycE/CCNE↓, 8,   E2Fs↓, 1,   Ki-67↓, 4,   P21↓, 1,   P21↑, 11,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 8,   pRB↑, 1,   p‑pRB↓, 1,   RB1↑, 1,   p‑RB1↓, 1,   Securin↓, 2,   TumCCA↓, 2,   TumCCA↑, 23,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 2,   CD24↓, 1,   cFos↓, 7,   CSCs↓, 8,   Diff↓, 1,   FGF↓, 1,   Gli↓, 1,   Gli1↓, 1,   HH↓, 1,   IGF-1↓, 1,   IGFBP3↑, 2,   JAG1↓, 1,   Jun↓, 1,   Ki-67↓, 4,   Let-7↑, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 5,   NOTCH1↓, 3,   NOTCH1↑, 1,   Shh↓, 2,   Smo↓, 1,   TumCG↓, 6,   TumCP↓, 16,   Wnt↓, 16,   ZFX↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AP-1↓, 7,   AXL↓, 1,   CA↓, 1,   Ca+2↑, 11,   CAFs/TAFs↓, 1,   CCN2/CTGF↓, 1,   Cdc42↑, 1,   E-cadherin↓, 2,   E-cadherin↑, 13,   EMT↓, 21,   EMT↑, 1,   FAK↓, 9,   p‑FAK↓, 1,   Fibronectin↓, 3,   MET↓, 1,   MMP-10↓, 1,   MMP1↓, 4,   MMP13↓, 3,   MMP2↓, 33,   MMP3↓, 3,   MMP7↓, 9,   MMP9↓, 40,   MMP9↑, 1,   MMPs↓, 8,   N-cadherin↓, 7,   PAI-1/SERPINE1↓, 1,   PDGF↓, 5,   Rho↓, 4,   ROCK1↓, 2,   ROCK1↑, 1,   Slug↓, 3,   Snail?, 1,   Snail↓, 7,   TET1↓, 1,   TGF-β↓, 7,   TIMP1↓, 2,   TIMP1↑, 1,   TIMP2↓, 2,   TIMP2↑, 5,   TSP-1↑, 2,   TumCA↓, 2,   TumCI↓, 14,   TumCMig↓, 18,   TumMeta↓, 11,   TumMeta↑, 1,   Twist↓, 5,   uPA↓, 53,   uPA↝, 1,   uPAR↓, 6,   Vim↓, 12,   Zeb1↓, 4,   ZEB2↓, 1,   β-catenin/ZEB1↓, 14,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 20,   CD31/PECAM-1↓, 2,   eNOS↓, 1,   Hif1a↓, 12,   NO↓, 1,   NO↑, 1,   VEGF↓, 30,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 8,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   CLDN2↓, 1,   EPR↑, 1,   GLUT1↓, 3,   MMP↓, 19,   NHE1↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD4+↓, 1,   CD44↓, 3,   COX2/PTGS2↓, 25,   CXCc↓, 1,   CXCL12↓, 1,   CXCR2↓, 1,   CXCR4↓, 4,   DR4↑, 2,   ICAM-1↓, 2,   IFN-γ↑, 1,   IL1↓, 2,   IL10↓, 3,   IL18↓, 1,   IL1β↓, 3,   IL2↑, 2,   IL4↓, 1,   IL6↓, 8,   IL8↓, 4,   Inflam↓, 5,   IRAK1↓, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 4,   MDSCs↓, 1,   NF-kB↓, 38,   NF-kB↑, 1,   NLRP3↓, 1,   p65↓, 3,   PD-L1↓, 2,   PGE2↓, 9,   PSA↓, 3,   RAGE↓, 1,   RANTES?, 1,   TCF↓, 1,   TCF↑, 1,   TLR4↓, 1,   TNF-α↓, 5,   TNF-α↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AhR↓, 1,   AR↓, 4,   CYP19↓, 1,   ER-α36↓, 1,   cl‑PPARα↓, 1,   PPARγ↓, 1,   PPARγ↑, 1,   RANKL↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 10,   BioAv↑, 7,   BioAv↝, 3,   BioEnh↑, 1,   ChemoSen↑, 13,   Dose?, 1,   Dose↓, 1,   Dose↑, 2,   Dose↝, 5,   eff↓, 1,   eff↑, 7,   eff↝, 4,   Half-Life↓, 5,   Half-Life↝, 4,   MDR1↓, 1,   P-gp/ABCB1↓, 1,   RadioS↑, 6,   selectivity↑, 7,   Synergy↑, 21,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 4,   CRP↓, 1,   E6↓, 2,   E7↓, 2,   EGFR↓, 15,   p‑EGFR↓, 1,   EZH2↓, 1,   Ferritin↓, 1,   FOXM1↓, 2,   HER2/EBBR2↓, 4,   IL6↓, 8,   LDH↑, 1,   Myc↓, 2,   PD-L1↓, 2,   PSA↓, 3,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 5,   antiD↑, 1,   AntiTum↑, 2,   cachexia↓, 1,   cardioP↑, 3,   chemoP↑, 4,   chemoPv↑, 5,   hepatoP↑, 3,   neuroP↑, 2,   radioP↑, 1,   RenoP↑, 4,   toxicity↑, 1,   toxicity↝, 2,   toxicity∅, 1,   TumVol↓, 1,   Wound Healing↓, 1,  
Total Targets: 452

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 15,   ARE↑, 1,   Catalase↑, 2,   GPx↑, 2,   GSH↑, 4,   GSTs↑, 1,   HO-1↑, 3,   MDA↓, 1,   NQO1↑, 1,   NRF2↑, 8,   Prx↑, 1,   RNS↓, 1,   ROS↓, 10,   SOD↑, 1,   SOD1↑, 1,   SOD2↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   FABP4↓, 1,   SIRT1↑, 1,   SREBF2⇅, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 2,   Casp3?, 1,   iNOS↓, 2,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 3,   p‑Akt↑, 1,   AMPKα↑, 1,   p‑CREB↑, 1,   ERK↑, 2,   IGF-1R↓, 1,   JAK↓, 1,   mTOR↑, 1,   PDGFR-BB↓, 1,   PI3K↑, 1,   PKCδ↓, 1,   STAT3↑, 1,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   p‑cMyc↑, 1,   HDAC↑, 1,   HOTAIR↑, 1,   other↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   p16↓, 1,   P53↓, 2,   Telomerase↓, 1,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

E2Fs↑, 1,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 2,   AntiAg↑, 2,   AP-1↓, 1,   MMP2↓, 2,   Rac1↑, 1,   TGF-β1↓, 1,   TIMP1↓, 1,   TIMP2↑, 1,   uPA↓, 1,   uPA↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   memfluid↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   IL10↑, 1,   IL1β↓, 1,   IL4↑, 1,   IL6↓, 3,   IL8↓, 2,   Imm↑, 1,   Imm↝, 1,   Inflam↓, 14,   MCP1/CCL2↓, 1,   NF-kB↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BChE↓, 1,   BDNF↑, 1,   MAOA↓, 1,   MAOB↓, 1,   TrkB↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

PPARγ↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 7,   BioAv↑, 1,   BioAv↝, 3,   ChemoSen↑, 1,   CYP1A1↑, 1,   CYP1A2↑, 1,   Dose↝, 1,   eff↑, 1,   Half-Life↝, 2,   Synergy↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

p‑BRCA1↑, 1,   IL6↓, 3,   TMAO↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 2,   AntiCan↑, 2,   AntiTum↑, 1,   cardioP↑, 2,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 1,   hepatoP↓, 1,   hepatoP↑, 6,   memory↑, 1,   neuroP↑, 7,   Obesity↓, 1,   Pain↓, 1,   radioP↑, 1,   Stroke↓, 2,   toxicity↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 2,   Bacteria↓, 2,   Diar↓, 1,   GutMicro↑, 1,  
Total Targets: 120

Scientific Paper Hit Count for: uPA, Urokinase plasminogen activator
14 Fisetin
4 Diindolylmethane
4 Quercetin
3 Artemisinin
3 Ashwagandha(Withaferin A)
3 EGCG (Epigallocatechin Gallate)
3 Silymarin (Milk Thistle) silibinin
2 Baicalein
2 Berberine
2 Indole-3-carbinol
2 Nimbolide
1 Apigenin (mainly Parsley)
1 Carnosic acid
1 Chrysin
1 Propolis -bee glue
1 Curcumin
1 Shilajit/Fulvic Acid
1 Garcinol
1 Ginkgolic acids
1 Genistein (soy isoflavone)
1 Hibiscus sabdariffa
1 Lycopene
1 Magnolol
1 Matrine
1 Morin
1 Naringin
1 Phenethyl isothiocyanate
1 Kaempferol
1 Resveratrol
1 Shikonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:428  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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