TumCD Cancer Research Results

TumCD, Tumor Cell Death: Click to Expand ⟱
Source:
Type:
Tumor Cell Death
Scientific Papers found: Click to Expand⟱
5944- Cela,    HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way
- in-vitro, AML, U937
TumCP↓, TumCCA↑, TumCD↑, HSP90↓, HSP70/HSPA5↑, cycD1/CCND1↓, CDK4↓, CDK6↓, ATPase↓,
6645- Cen,    Can Asiatic Acid from Centella asiatica Be a Potential Remedy in Cancer Therapy?—A Review
- Review, Var, NA
TumCD↑, TumCG↓, TumMeta↓, PI3K↓, Akt↓, mTOR↓, P70S6K↓, STAT3↓, N-cadherin↓, β-catenin/ZEB1↓, CLDN1↓, Vim↓, TumAuto↑, *BioAv↓, Casp3↑, ROS↑, MMP15↓, MMP↓, eff↑, *toxicity↓,
7183- CHA,    The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells
- in-vitro, AML, HL-60 - in-vitro, AML, KG-1 - in-vitro, lymphoma, U937
TumCD↓, SUV39H↓, CD11b↑, Diff↑, H3K9↓, eff↑,
7165- CHA,    The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase
- in-vitro, Cerv, HeLa
ROS↑, TumCD↑, TrxR1↓, other↝, GSR↓, Trx↓, eff↓,
5991- Chit,    Chitosan-Based Nanoencapsulated Essential Oils: Potential Leads against Breast Cancer Cells in Preclinical Studies
- Review, BC, NA
*other↝, *BioAv↓, eff↑, toxicity↓, eff↑, TumCD↑, Half-Life↑, selectivity↑, EPR↑, ROS↑, Apoptosis↑, eff↑,
6075- CHL,  docx,    The effect of the combination therapy with chlorophyllin, a glutathione transferase P1-1 inhibitor, and docetaxel on triple-negative breast cancer invasion and metastasis in vivo/in vitro
- vitro+vivo, BC, 4T1
TumCMig↓, eff↑, TumMeta↓, TumCCA↑, Trx↓, ROS↓, TumCD↑, GSTP1/GSTπ↓,
6131- CHr,  Bor,  Z,    Fabrication of phenyl boronic acid modified pH-responsive zinc oxide nanoparticles as targeted delivery of chrysin on human A549 cells
- in-vitro, Lung, A549
*BioAv↑, ROS↑, TumCD↑, TumCCA↑, MMP2↓, TumMeta↓, TumCI↓, GSH↓, eff↑,
6139- CHr,    Chrysin and its nanoformulations in cancer therapy: A systematic review of their radiosensitizing, phototherapy-enhancing potentials
- Review, Var, NA
RadioS↑, PhotoS↑, ROS↑, DNAdam↑, TumCCA↑, TumCD↑, selectivity↑, *ROS↓, *Inflam↓, *DNAdam↓, *antiOx↑, *lipid-P↓, *BioAv↑, eff↑, GSH↓, Catalase↓, ALAT↓, Ca+2↓, MDA↑,
2791- CHr,    Chrysin attenuates progression of ovarian cancer cells by regulating signaling cascades and mitochondrial dysfunction
- in-vitro, Ovarian, OV90
TumCP↓, TumCD↑, ROS↑, Ca+2↑, MMP↓, MAPK↑, PI3K↑, p‑Akt↑, PCNA↓, p‑p70S6↑, p‑ERK↑, p38↑, JNK↑, DNAdam↑, TumCCA↑, chemoP↑,
4761- CoQ10,    Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancer
- in-vitro, PC, NA - in-vivo, PC, NA
*ETC↝, ROS↑, *antiOx↑, ROS↑, OCR↓, MMP↓, TumCD↑, TumCG↓, other↝,
4769- CoQ10,    CoQ10 Is Key for Cellular Energy and Cancer Support
- Review, Var, NA
Risk↓, TumCG↓, angioG↓, TumCD↑, *toxicity↓, *BioAv↑, MMPs↓, Inflam↓, chemoP↑, cardioP↑, *ROS↓, *toxicity↝, Dose?,
6524- CRV,    d-Carvone inhibits the JAK/STAT3 signaling pathway and induced the apoptotic cell death in the human gastric cancer AGS cells
- in-vitro, GC, AGS
ROS↑, MMP↝, JAK↓, STAT3↓, TumCD↑,
1596- Cu,  CDT,    Unveiling the promising anticancer effect of copper-based compounds: a comprehensive review
- Review, NA, NA
TumCD↑, Apoptosis↓, ROS↑, angioG↑, Cupro↑, Paraptosis↑, eff↑, eff↓, selectivity↑, DNAdam↑, eff↑, eff↑, eff↑, eff↑, Fenton↑, H2O2↑, eff↑, eff↑, eff↑, RadioS↑, ChemoSen↑, eff↑, *toxicity↝, other↑, eff↑,
6214- CUR,    Curcumin Nanoparticles-related Non-invasive Tumor Therapy, and Cardiotoxicity Relieve
TumCD↓, TumCI↓, *Inflam↓, *antiOx↓, *AntiTum↓, NF-kB↓, COX2↓, Casp9↓, ROS↑, BioAv↑, RadioS↑, ChemoSen↑, Imm↑, PhotoS↑, sonoS↑, 5LO↓, iNOS↓, IL2↓, TNF-α↓, Casp9↑, Casp3↑, Bcl-2↓, BAX↑, Apoptosis↑, ER Stress↑, cycD1/CCND1↓, CDK2↓, CycB/CCNB1↓, TumCCA↑, MMPs↓, *radioP↑, chemoP↑, hepatoP↑, cardioP↑, eff↑, PhotoS↑, eff↑, ROS↑, GSH↓,
6218- CUR,    Exploring the Thioredoxin System as a Therapeutic Target in Cancer: Mechanisms and Implications
- Review, Var, NA
NF-kB↓, TrxR↓, ROS↑, TumMeta↓, TumCD↑, RadioS↑, BioAv↝, BioAv↑,
474- CUR,    Modification of radiosensitivity by Curcumin in human pancreatic cancer cell lines
- in-vitro, PC, PANC1 - in-vitro, PC, MIA PaCa-2
TumCD↑, Apoptosis↑, DNAdam↑, γH2AX↑, TumCCA↑,
6672- Deg,    Deguelin, an Akt inhibitor, down-regulates NF-κB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice
- vitro+vivo, CRC, COLO205 - in-vitro, CRC, HCT116
Akt↑, AntiTum↑, IL8↓, p‑IKKα↓, NF-kB↓, TumCD↑, Apoptosis↑, cFLIP↓, Bcl-2↓, Bcl-xL↓, TumVol↓,
6696- DFC,  MET,    Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma
- in-vitro, GBM, GBM
compI↓, Glycolysis↓, OCR↓, Glycolysis↑, lactateProd↓, eff↑, TumCP↓, TumCMig↓, TumCD∅,
6665- DFE,    Cytotoxic Effect of Phoenix dactylifera (Iraqi Date) Leaves and Fruits Extracts against Breast Cancers Cell Lines
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, CAL51 - in-vitro, BC, MCF7
TumCD↑, eff↓, selectivity↑, AntiCan↑, TumCP↓, MMP↓, cl‑Casp3↑, cl‑PARP↑,
6668- DFE,  AgNPs,    Saponin-Derived Silver Nanoparticles from Phoenix dactylifera (Ajwa Dates) Exhibit Broad-Spectrum Bioactivities Combating Bacterial Infections
- in-vitro, Lung, A549
*AntiBio↑, antiOx↑, TumCD↑, ROS↑, DNAdam↑, *Catalase↑, *GPx↑, *SOD↑, *ROS↓,
4456- DFE,    Induction of apoptosis and cell cycle arrest by ethyl acetate fraction of Phoenix dactylifera L. (Ajwa dates) in prostate cancer cells
- in-vitro, Pca, PC3
TumCD↑, MMP↓, mt-ROS↑, Apoptosis↑, TumCCA↑,
1863- dietFMD,  Chemo,    Effect of fasting on cancer: A narrative review of scientific evidence
- Review, Var, NA
eff↑, ChemoSideEff↓, ChemoSen↑, Insulin↓, HDAC↓, IGF-1↓, STAT5↓, BG↓, MAPK↓, HO-1↓, ATG3↑, Beclin-1↑, p62↑, SIRT1↑, LAMP2↑, OXPHOS↑, ROS↑, P53↑, DNAdam↑, TumCD↑, ATP↑, Treg lymp↓, M2 MC↓, CD8+↑, Glycolysis↓, GutMicro↑, GutMicro↑, Warburg↓, Dose↝,
1847- dietFMD,  VitC,    Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers
- in-vitro, PC, PANC1
TumCG↓, ChemoSen↑, eff↑, HO-1↓, Ferritin↓, Iron↑, ROS↑, TumCD↑, IGF-1↓, eff↓, eff↓,
6345- DRE,    Human clinical trials on for cancer killing dandelion extract
- Review, AML, NA
TumCD↑,
6318- DRE,    Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways
- vitro+vivo, CRC, HCT116 - NA, Nor, NCM460
TumCD↑, Apoptosis↑, Casp8↑, selectivity↑, TumCMig↓, selectivity↑, Dose↝, toxicity↓, TumCG↓, MMP↓, mt-ROS↑, *ROS↓, BID↑, Bcl-2↓, PARP↓, NF-kB↑, *NF-kB↓, Casp1↑, *Casp1↓, COX2↑, OXPHOS↓, ETC↓,
6354- DRE,    Taraxacum officinale L. in leukemia and lymphoma: current knowledge and prospects for horticulture
- Review, AML, NA
ROS↑, mt-Apoptosis↑, TumCCA↑, PI3K↓, Akt↓, STAT3↓, Dose↝, *hepatoP↑, Casp8↑, mtDam↑, TumCD↑, selectivity↑, DNAdam↑, BAX↑, P53↑, Bcl-2↓, CSCs↓, *toxicity↓, tumCV↓, Imm↑, FAK↓, mTOR↓, ChemoSen↑, eff↝, eff↑,
6367- DRE,    Antioxidant and antimicrobial activities of Dandelion root extract (Taraxacum officinale) and its cytotoxic effect on MDA-MB-231 breast cancer cells
- in-vitro, BC, MDA-MB-231
TumCD↑, *antiOx↑, *ROS↓, tumCV↓, Apoptosis↑, ROS↑, TumCCA↑, MOMP↑, ROS↑,
6364- DRE,    Dandelion Root Extract Sensitizes Leukemia Cells to VP-16 Induced Cell Death
- in-vitro, CLL, NA
TumCP↓, MMP↓, ROS↑, TumCD↑, ChemoSen↑, chemoP↑, QoL↑,
6744- DSF,    Disulfiram modulated ROS-MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, T47D
TumCD↑, ChemoSen↑, BAX↑, Apoptosis↑, CSCs↓, ROS↑, eff↝, JNK↑, p38↑, NF-kB↓,
4915- DSF,  Cu,    Disulfiram: A novel repurposed drug for cancer therapy
- Review, Var, NA
ROS↑, TumCD↑, NF-kB↓, CSCs↓, ChemoSen↑, RadioS↑, eff↑, selectivity↑, Proteasome?,
5008- DSF,  Cu,    Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis
- in-vitro, HCC, NA
selectivity↑, TumCD↑, TumCMig↓, TumCI↓, angioG↓, mtDam↑, Iron↑, lipid-P↑, Ferroptosis↑, NF-kB↑, p‑p62↑, Keap1↓, eff↑, eff↓, ChemoSen↑,
5009- DSF,  Cu,    Activation of Oxidative Stress and Down-Regulation of Nuclear Factor Erythroid 2-Related Factor May Be Responsible for Disulfiram/Copper Complex Induced Apoptosis in Lymphoid Malignancy Cell Lines
- vitro+vivo, lymphoma, NA
AntiTum↑, ROS↑, JNK↑, NRF2↓, eff↓, TumCD↑,
5006- DSF,  Cu,    Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition
- vitro+vivo, lymphoma, NA
TumCD↑, TumCP↑, Apoptosis↑, NRF2↓, ROS↑, p‑JNK↑, p65↓, eff↓, NF-kB↓,
6608- Ech,  CBC,    The pro-apoptosis effects of Echinacea purpurea and Cannabis sativa extracts in human lung cancer cells through caspase-dependent pathway
- in-vitro, Lung, A549
tumCV↓, Apoptosis↑, TumCCA↑, ROS↑, Casp3↑, TumCD↑,
3208- EGCG,    Induction of Endoplasmic Reticulum Stress Pathway by Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Activation of PERK/p-eIF2α/ATF4 and IRE1α
- in-vitro, Colon, HT29 - in-vitro, Nor, 3T3
TumCD↓, ER Stress↑, GRP78/BiP↑, PERK↑, eIF2α↑, ATF4↑, IRE1↑, Apoptosis↑, Casp3↑, Casp7↑, Wnt↓, β-catenin/ZEB1↓, *toxicity∅, UPR↑,
5931- EGCG,  BTZ,    EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism
- in-vitro, Pca, PC3
TumAuto↑, CHOP/DDIT3↓, TumCD↓, eff↓,
6834- EMD,    Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9
- in-vitro, Cerv, HeLa
AntiCan↑, TumCP↓, Apoptosis↑, Casp3↑, Casp9↑, cl‑PARP↑, TumCD↑, DNAdam↑,
5223- EMD,    Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways
- in-vitro, CRC, DLD1 - in-vitro, Nor, CCD841
tumCV↓, Apoptosis↑, selectivity↑, Casp↑, Bcl-2↓, MMP↓, TumCD↑, MAPK↓, JNK↓, PI3K↓, Akt↓, NF-kB↓, STAT↓, Diff↓, P53↑, PARP↓,
5256- EP,    Pulsed electric fields: a sharp sword in the battle against cancers
- Review, Var, NA
BioAv↑, TumCD↑, MMP↓, Apoptosis↑, TumCCA↑, Imm↑, RadioS↑, ChemoSen↑,
5489- EP,    Electroporation and cell killing by milli- to nanosecond pulses and avoiding neuromuscular stimulation in cancer ablation
- in-vitro, Colon, NA
eff↑, TumCD↑, MusCon↓, Temp↓, eff↑, eff↓, eff↑, eff∅, other↑,
5491- EP,    Nano-pulse stimulation™ therapy (NPS™) is superior to cryoablation in clearing murine melanoma tumors
- in-vivo, Melanoma, B16-F10
TumCD↑, eff↑, MusCon↓, CellMemb↑, ER Stress↑, other↝,
5493- EP,    Schottky nanodiodes array enabled triboelectric nanosecond pulse generator for ultralow-cost tumor therapy
- Review, Var, NA
other↝, other↝, Ca+2↑, TumCD↑, Imm↑, TumCG↓, other↓,
5494- EP,    An Overview of Subnanosecond Pulsed Electric Field Biological Effects: Toward Contactless Technologies for Cancer Treatment
- Review, Var, NA
other↝, ROS↑, Temp∅, CellMemb↑, Ca+2↑, Apoptosis↑, TumCD↑, MMP↓, necrosis↑, TumVol↓, Remission↑,
5519- EP,    Nanosecond Pulsed Electric Fields (nsPEFs) for Precision Intracellular Oncotherapy: Recent Advances and Emerging Directions
- Review, Var, NA
MMP↓, Ca+2↑, eff↑, ER Stress↑, selectivity↑, CSCs↓, CD44↓, CD133↓, ROS↑, Imm↑, DNAdam↑, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp9↑, TumCD↑, Fas↑, UPR↑, Dose↝, Dose↝, Dose↓, Dose↑, HMGB1↓, eff↑, EPR↑, ChemoSen↑, ETC↝, *AntiAge↑, *Hif1a↑, *SIRT1↑,
6794- EPA,    EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: role of ROS accumulation, caspase-8 activation, and autophagy induction
- in-vitro, BC, NA - vitro+vivo, PC, MIA PaCa-2
ROS↑, Casp8↑, Apoptosis↑, ROS↑, TumCG↓, TumCD↑, eff↑,
6576- EU,    Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53
- in-vitro, HCC, HepG2
TumCD↑, selectivity↑, Apoptosis↓, ChrMod↑, DNAdam↑, P53↑, BAX↑, Bcl-2↓, Cyt‑c↑, eff↑, TumCCA↑,
6584- EU,    Eurycoma longifolia: an overview on the pharmacological properties for the treatment of common cancer
- Review, Var, NA
*AntiAge↑, *Inflam↓, *antiOx↑, TumCD↑, Bcl-2↓, cl‑Casp7↑, cl‑PARP↑, BAX↑, P53↑, tumCV↓, selectivity↑, *testos↑, *PSA∅,
6586- EU,    Unfermented Freeze-Dried Leaf Extract of Tongkat Ali (Eurycoma longifolia Jack.) Induced Cytotoxicity and Apoptosis in MDA-MB-231 and MCF-7 Breast Cancer Cell Lines
TumCD↑, DNAdam↑, TumCCA↑, Cyt‑c↑, Casp3↑,
6389- Eug,    Molecular Insights into the Management of Eugenol's Anticancer Action Against Colon Cancer: A Detailed Review
- Review, Colon, NA
Apoptosis↓, TumCCA↓, Inflam↓, TumMeta↓, BioAv↑, eff↓, Half-Life↓, *ROS↓, *RNS↓, *SOD↓, *Catalase↑, *GSTs↑, *MAOA↓, *neuroP↑, *DNAdam↓, Apoptosis↑, ROS↑, selectivity↑, MMP↓, Cyt‑c↓, Casp3↑, Casp9↑, TumCD↑, BAX↑, BAD↑, APAF1↑, Bcl-2↓, Bcl-xL↓, P53↑, cl‑PARP↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, CDK2↓, CDK4↓, P21↑, p27↑, NF-kB↓, COX2↓, PGE2↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, MMPs↓, EMT↓, Snail↓, Slug↓, Zeb1↓, E-cadherin↑, ChemoSen↑,
6339- Eug,    Induction of apoptosis by eugenol in human breast cancer cells
- in-vitro, BC, NA
TumCG↓, TumCP↓, TumCD↑, GSH↓, lipid-P↑,

Showing Research Papers: 51 to 100 of 174
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 174

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

H3K9↓, 1,   SUV39H↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↓, 1,   compI↓, 1,   Fenton↑, 1,   Ferroptosis↑, 1,   GSH↓, 4,   GSR↓, 1,   GSTP1/GSTπ↓, 1,   H2O2↑, 1,   HO-1↓, 2,   Iron↑, 2,   Keap1↓, 1,   lipid-P↑, 2,   MDA↑, 1,   NRF2↓, 2,   OXPHOS↓, 1,   OXPHOS↑, 1,   ROS↓, 1,   ROS↑, 30,   mt-ROS↑, 2,   Trx↓, 2,   TrxR↓, 1,   TrxR1↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   ETC↓, 1,   ETC↝, 1,   Insulin↓, 1,   MMP↓, 12,   MMP↝, 1,   mtDam↑, 2,   OCR↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   Glycolysis↓, 2,   Glycolysis↑, 1,   lactateProd↓, 1,   SIRT1↑, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 4,   Akt↑, 1,   p‑Akt↑, 1,   APAF1↑, 1,   Apoptosis↓, 3,   Apoptosis↑, 17,   mt-Apoptosis↑, 1,   BAD↑, 1,   BAX↑, 6,   Bcl-2↓, 8,   Bcl-xL↓, 2,   BID↑, 1,   Casp↑, 1,   Casp1↑, 1,   Casp3↑, 8,   cl‑Casp3↑, 1,   Casp7↑, 1,   cl‑Casp7↑, 1,   Casp8↑, 3,   Casp9↓, 1,   Casp9↑, 5,   cFLIP↓, 1,   Cupro↑, 1,   Cyt‑c↓, 1,   Cyt‑c↑, 3,   Fas↑, 1,   Ferroptosis↑, 1,   iNOS↓, 1,   JNK↓, 1,   JNK↑, 3,   p‑JNK↑, 1,   MAPK↓, 3,   MAPK↑, 1,   MOMP↑, 2,   necrosis↑, 1,   p27↑, 1,   p38↑, 2,   Paraptosis↑, 1,   Proteasome?, 1,   TumCD↓, 4,   TumCD↑, 45,   TumCD∅, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

p‑p70S6↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ChrMod↑, 1,   other↓, 1,   other↑, 2,   other↝, 6,   PhotoS↑, 3,   sonoS↑, 1,   tumCV↓, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   eIF2α↑, 1,   ER Stress↑, 4,   GRP78/BiP↑, 1,   HSP70/HSPA5↑, 1,   HSP90↓, 1,   IRE1↑, 1,   PERK↑, 1,   UPR↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↑, 1,   Beclin-1↑, 1,   LAMP2↑, 1,   p62↑, 1,   p‑p62↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 11,   P53↑, 6,   PARP↓, 2,   cl‑PARP↑, 4,   PCNA↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 2,   CDK4↓, 2,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 3,   P21↑, 1,   TumCCA↓, 1,   TumCCA↑, 15,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   CD44↓, 1,   CSCs↓, 4,   Diff↓, 1,   Diff↑, 1,   EMT↓, 1,   p‑ERK↑, 1,   HDAC↓, 1,   IGF-1↓, 2,   mTOR↓, 3,   P70S6K↓, 1,   PI3K↓, 4,   PI3K↑, 1,   STAT↓, 1,   STAT3↓, 3,   STAT5↓, 1,   TumCG↓, 8,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   ATPase↓, 1,   Ca+2↓, 1,   Ca+2↑, 4,   CD11b↑, 1,   CLDN1↓, 1,   E-cadherin↑, 1,   FAK↓, 1,   MMP15↓, 1,   MMP2↓, 1,   MMPs↓, 3,   N-cadherin↓, 1,   Slug↓, 1,   Snail↓, 1,   Treg lymp↓, 1,   TumCI↓, 3,   TumCMig↓, 4,   TumCP↓, 7,   TumCP↑, 1,   TumMeta↓, 5,   Vim↓, 1,   Zeb1↓, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 1,   ATF4↑, 1,   EPR↑, 2,  

Barriers & Transport(tgid=15) ⓘ

CellMemb↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 2,   COX2↑, 1,   HMGB1↓, 1,   p‑IKKα↓, 1,   IL2↓, 1,   IL8↓, 1,   Imm↑, 5,   Inflam↓, 2,   JAK↓, 1,   M2 MC↓, 1,   NF-kB↓, 8,   NF-kB↑, 2,   p65↓, 1,   PGE2↓, 1,   TNF-α↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

Temp↓, 1,   Temp∅, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 4,   BioAv↝, 1,   ChemoSen↑, 12,   Dose?, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 5,   eff↓, 11,   eff↑, 34,   eff↝, 2,   eff∅, 1,   Half-Life↓, 1,   Half-Life↑, 1,   RadioS↑, 6,   selectivity↑, 14,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   BG↓, 1,   Ferritin↓, 1,   GutMicro↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiTum↑, 2,   cardioP↑, 2,   chemoP↑, 4,   ChemoSideEff↓, 1,   hepatoP↑, 1,   MusCon↓, 2,   QoL↑, 1,   Remission↑, 1,   Risk↓, 1,   toxicity↓, 2,   TumVol↓, 2,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 1,  
Total Targets: 214

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 4,   Catalase↑, 2,   GPx↑, 1,   GSTs↑, 1,   lipid-P↓, 1,   RNS↓, 1,   ROS↓, 6,   SOD↓, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ETC↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Casp1↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 3,   NF-kB↓, 1,   PSA∅, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

MAOA↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

PSA∅, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiTum↓, 1,   hepatoP↑, 1,   neuroP↑, 1,   radioP↑, 1,   toxicity↓, 3,   toxicity↝, 2,   toxicity∅, 1,  
Total Targets: 33

Scientific Paper Hit Count for: TumCD, Tumor Cell Death
23 Silver-NanoParticles
12 Magnetic Fields
9 Vitamin C (Ascorbic Acid)
8 Magnetic Field Rotating
6 Electrical Pulses
6 Selenite (Sodium)
5 Curcumin
5 Copper and Cu NanoParticles
5 Dandelion Root
5 Disulfiram
5 Phenethyl isothiocyanate
4 Chemotherapy
4 Eugenol
4 Quercetin
4 VitK3,menadione
3 Rosmarinic acid
3 Astaxanthin
3 Melatonin
3 Metformin
3 Chrysin
3 Date Fruit Extract
3 Eurycomanone
3 Fisetin
3 salinomycin
2 3-bromopyruvate
2 Radiotherapy/Radiation
2 Apigenin (mainly Parsley)
2 Ashwagandha(Withaferin A)
2 Berberine
2 Betulinic acid
2 Boron
2 α-Bisabolol / Chamomile oil
2 Caffeic acid
2 chaetocin
2 Coenzyme Q10
2 diet FMD Fasting Mimicking Diet
2 EGCG (Epigallocatechin Gallate)
2 Emodin
2 Fenbendazole
2 Ginkgetin
2 Phenylbutyrate
2 Selenium
1 1,8-Cineole
1 2-DeoxyGlucose
1 Auranofin
1 Gold NanoParticles
1 Hyperthermia
1 Anethole/trans-Anethole
1 Anti-oxidants
1 Aloe anthraquinones
1 Baicalein
1 Photodynamic Therapy
1 Bufalin/Huachansu
1 Bacopa monnieri
1 Carnosic acid
1 Capsaicin
1 Celastrol
1 Centella asiatica / Gotu kola → asiaticoside
1 chitosan
1 Chlorophyllin
1 Docetaxel
1 Zinc
1 Carvone
1 chemodynamic therapy
1 Deguelin
1 Diclofenac
1 Echinacea
1 Cannabichromene
1 Bortezomib
1 eicosapentaenoic acid
1 ferumoxytol
1 Formononetin
1 Galloflavin
1 Ginkgo biloba
1 Hydrogen Gas
1 Honokiol
1 Laetrile B17 Amygdalin
1 Linalool
1 Luteolin
1 Methylene blue
1 SonoDynamic Therapy UltraSound
1 Caffeine
1 methotrexate
1 Nimbolide
1 Propyl gallate
1 Piperlongumine
1 Resveratrol
1 Pterostilbene
1 Perilla
1 Selenium NanoParticles
1 Sulforaphane (mainly Broccoli)
1 Silymarin (Milk Thistle) silibinin
1 Shikonin
1 Spermidine
1 Thymoquinone
1 Urolithin
1 Magnesium
1 Whole Body Vibration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:619  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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