eff Cancer Research Results

eff, efficacy: Click to Expand ⟱
Source:
Type:
Power to enhance an anti cancer effect
Scientific Papers found: Click to Expand⟱
1992- PTL,    Parthenolide induces ROS-dependent cell death in human gastric cancer cell
- in-vitro, BC, MGC803
TumCCA↑, Casp↑, Apoptosis↑, Necroptosis↑, RIP1↓, RIP3↑, MLKL↑, ROS↑, eff↓,
5032- PTS,    Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism
- in-vivo, Melanoma, NA
TumCG↓, NRF2↓, GR↓, BBB↑, ACTH↓, eff↑,
4703- PTS,  RES,    Pterostilbene and resveratrol: Exploring their protective mechanisms against skin photoaging - A scoping review
- in-vivo, Nor, NA
*AntiAge↑, *eff↑, *Inflam↓, *AntiCan↑, *ROS↓, *Catalase↑, *GSR↑, *HO-1↑, *NAD↑, *NQO1↑, *SOD↑, *NRF2↑,
4690- PTS,  immuno,    Pterostilbene: Mechanisms of its action as oncostatic agent in cell models and in vivo studies
- Review, Var, NA
eff↑, Half-Life↑, TumCG↓, TumMeta↓, angioG↓, CSCs↓, Apoptosis↑, Synergy↑, CD44↓, CD24↓,
4689- PTS,    Pterostilbene Suppresses both Cancer Cells and Cancer Stem-Like Cells in Cervical Cancer with Superior Bioavailability to Resveratrol
- in-vitro, Cerv, HeLa
eff↑, TumCCA↑, ROS↑, MMP2↓, MMP9↓, CSCs↓, CD133↓, OCT4↓, SOX2↓, Nanog↓, STAT3↓, BioAv↑, TumCI↓, ROS↑, Apoptosis↑,
8606- PumpSO,  Tamsu,    Pumpkin seed oil (Cucurbita pepo) versus tamsulosin for benign prostatic hyperplasia symptom relief: a single-blind randomized clinical trial
- Trial, BPH, NA
*Dose?, *toxicity↓, *eff↓, *IPSS↝, *other↝, *UFR?, *5-AR↓, *Inflam↓,
2340- QC,    Oral Squamous Cell Carcinoma Cells with Acquired Resistance to Erlotinib Are Sensitive to Anti-Cancer Effect of Quercetin via Pyruvate Kinase M2 (PKM2)
- in-vitro, OS, NA
TumCG↓, GlucoseCon↓, TumCI↓, GLUT1↓, PKM2↓, LDHA↓, Glycolysis↓, lactateProd↓, HK2↓, eff↑,
2341- QC,    Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
MMP2↓, MMP9↓, VEGF↓, Glycolysis↓, lactateProd↓, PKM2↓, GLUT1↓, LDHA↓, TumAuto↑, Akt↓, mTOR↓, TumMeta↓, MMP3↓, eff↓, GlucoseCon↓, lactateProd↓, TumAuto↑, LC3B-II↑,
3343- QC,    Quercetin, a Flavonoid with Great Pharmacological Capacity
- Review, Var, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *angioG↓, *Inflam↓, *BioAv↓, *Half-Life↑, *GSH↑, *SOD↑, *Catalase↑, *Nrf1↑, *BP↓, *cardioP↑, *IL10↓, *TNF-α↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroP↑, *Pain↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL17↓, *MCP1/CCL2↓, PKCδ↓, ERK↓, BAX↓, cMyc↓, KRAS↓, ROS↓, selectivity↑, tumCV↓, Apoptosis↑, TumCCA↑, ChemoSen↑, P-gp/ABCB1↓, Synergy↑, Synergy↑, Synergy↑, Synergy↑, CycB/CCNB1↓, CDK1↓, CDK4↓, CDK2↓, TOP2↓, Cyt‑c↑, cl‑PARP↑, MMP↓, HSP70/HSPA5↓, HSP90↓, MDM2↓, RAS↓, eff↑,
3611- QC,    Quercetin and vitamin C supplementation: effects on lipid profile and muscle damage in male athletes
- Trial, Nor, NA
*eff↝, *LDH↓,
4686- QC,    Quercetin suppresses endometrial cancer stem cells via ERα-mediated inhibition of STAT3 signaling
- in-vitro, EC, EMN8 - in-vitro, EC, EMN21
CSCs↓, ALDH1A1↓, cMyc↓, Nanog↓, OCT4↓, STAT3↓, JAK2↓, STAT3↓, eff↑,
5030- QC,    Quercetin-derived microbial metabolite DOPAC potentiates CD8+ T cell anti-tumor immunity via NRF2-mediated mitophagy
- in-vivo, Nor, NA
*MitoP↑, *NRF2↑, Synergy↑, *eff↓, *GutMicro↑,
41- QC,    Quercetin induces mitochondrial-derived apoptosis via reactive oxygen species-mediated ERK activation in HL-60 leukemia cells and xenograft
- vitro+vivo, AML, HL-60
Casp8↑, Casp9↑, Casp3↑, ROS↑, ERK↑, cl‑PARP↑, MMP↓, eff↓,
50- QC,    Anticancer effect and mechanism of polymer micelle-encapsulated quercetin on ovarian cancer
- vitro+vivo, Ovarian, A2780S
Casp3↑, Casp9↑, Mcl-1↓, Bcl-2↓, BAX↑, angioG↓, TumCG↓, Apoptosis↑, p‑p44↓, Akt↓, TumCP↓, eff↑,
75- QC,  ENZ,    Quercetin targets hnRNPA1 to overcome enzalutamide resistance in prostate cancer cells
- in-vitro, Pca, HEK293 - in-vitro, NA, 22Rv1 - in-vitro, NA, C4-2B
hnRNPA1↓, PSA↓, NKX3.1↓, FKBP5↓, UBE2C↓, AR-FL↓, AR-V7↑, AR↓, eff↑, TumVol↓, BioAv↓,
77- QC,  EGCG,    The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition
- in-vitro, Pca, CD44+ - in-vitro, NA, CD133+ - in-vitro, NA, PC3 - in-vitro, NA, LNCaP
Casp3↑, Casp7↑, Bcl-2↓, survivin↓, XIAP↓, EMT↓, Vim↓, Slug↓, Snail↓, β-catenin/ZEB1↓, LEF1↓, TCF↓, eff↑, CSCs↓, TumCG↓, tumCV↓,
6056- RES,  SeNPs,    A comparative study of resveratrol and resveratrol-functional selenium nanoparticles: Inhibiting amyloid β aggregation and reactive oxygen species formation properties
- Study, AD, NA
*antiOx↑, *eff↑, *ROS↓, *Apoptosis↓, *Aβ↓,
1511- RES,  Chemo,    Combination therapy in combating cancer
- Review, Var, NA
eff↑, *NRF2↑, *GSH↑, *ROS↓, chemoPv↑, ChemoSideEff↓,
2567- RES,    Neuroprotective Effects of Resveratrol in Ischemic Brain Injury
- Review, Stroke, NA
*eff↑, *neuroP↑, *antiOx↑, *Inflam↓, *cardioP↑, *AntiAg↑,
2566- RES,    A comprehensive review on the neuroprotective potential of resveratrol in ischemic stroke
- Review, Stroke, NA
*neuroP↑, *NRF2↑, *SIRT1↑, *PGC-1α↑, *FOXO↑, *HO-1↑, *NQO1↑, *ROS↓, *BP↓, *BioAv↓, *Half-Life↝, *AMPK↑, *GSK‐3β↓, *eff↑, *AntiAg↑, *BBB↓, *Inflam↓, *MPO↓, *TLR4↓, *NF-kB↓, *p65↓, *MMP9↓, *TNF-α↓, *IL1β↓, *PPARγ↑, *MMP↑, *ATP↑, *Cyt‑c∅, *mt-lipid-P↓, *H2O2↓, *HSP70/HSPA5↝, *Mets↝, *eff↑, *eff↑, *motorD↑, *MDA↓, *NADH:NAD↑, eff↑, eff↑,
2442- RES,    High absorption but very low bioavailability of oral resveratrol in humans
- in-vitro, Nor, NA
BioAv↝, Half-Life↝, BioAv↓, eff↝,
2441- RES,    Anti-Cancer Properties of Resveratrol: A Focus on Its Impact on Mitochondrial Functions
- Review, Var, NA
*toxicity↓, *BioAv↝, *Dose↝, *hepatoP↑, *neuroP↑, *AntiAg↑, *COX2/PTGS2↓, *antiOx↑, *ROS↓, *ROS↑, PI3K↓, Akt↓, NF-kB↓, Wnt↓, β-catenin/ZEB1↓, NRF2↑, GPx↑, HO-1↑, BioEnh?, PTEN↑, ChemoSen↑, eff↑, mt-ROS↑, Warburg↓, Glycolysis↓, GlucoseCon↓, GLUT1↓, lactateProd↓, HK2↓, EGFR↓, cMyc↓, ROS↝, MMPs↓, MMP7↓, survivin↓, TumCP↓, TumCMig↓, TumCI↓,
3087- RES,    Resveratrol cytotoxicity is energy-dependent
- Review, Var, NA
OXPHOS↓, eff↝, Synergy↑,
3055- RES,    Resveratrol and Tumor Microenvironment: Mechanistic Basis and Therapeutic Targets
- Review, Var, NA
BioAv↓, BioAv↓, Dose↑, eff↑, eff↑, Dose↑, BioAv↑, ROS↑, MMP↓, P21↑, p27/CDKN1B↑, TumCCA↑, ChemoSen↑, COX2/PTGS2↓, 5LO↓, VEGF↓, IL1↓, IL6↓, IL8↓, AR↓, PSA↓, MAPK↓, Hif1a↓, Glycolysis↓, miR-21↓, PTEN↑, Half-Life↝, *IGF-1↓, *IGFBP3↑, Half-Life↓,
4666- RES,    Structural modification of resveratrol analogue exhibits anticancer activity against lung cancer stem cells via suppression of Akt signaling pathway
- in-vitro, Lung, H23 - in-vitro, Lung, H292 - in-vitro, Lung, A549
CSCs↓, eff↑, Akt↓, GSK‐3β↑, SOX2↓, cMyc↓, TumCCA↑, ROS↑, Apoptosis↑,
4662- RES,    A Promising Resveratrol Analogue Suppresses CSCs in Non-Small-Cell Lung Cancer via Inhibition of the ErbB2 Signaling Pathway
- in-vitro, NSCLC, A549 - in-vitro, NSCLC, H460
CSCs↓, CD133↓, OCT4↓, β-catenin/ZEB1↓, HER2/EBBR2↓, TumCP↓, PI3K↓, Akt↓, ALDH1A1↓, eff↑,
6811- RF,    Continuous Exposure to 1.7 GHz LTE Electromagnetic Fields Increases Intracellular Reactive Oxygen Species to Decrease Human Cell Proliferation and Induce Senescence
- in-vitro, Liver, HUH7 - in-vitro, Liver, Hep3B - in-vitro, Cerv, HeLa - in-vitro, neuroblastoma, SH-SY5Y - in-vitro, Nor, IMR90
TumCP↓, eff↑, ROS↑, eff↓,
6809- RF,    Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields
- in-vitro, GBM, U251
TumCP↓, Dose↝, eff↑, other↝, Dose↝, Dose↝, other↝, VGCC↑, Ca+2↑,
6808- RF,    Safety and Efficacy of amplitude-modulated radiofrequency electromagnetic fields in advanced hepatocellular carcinoma
- Trial, HCC, NA
OS↑, *toxicity↓, Dose↝, TumCG↓, Dose↝, Dose↝, Dose↝, eff↑,
3461- RF,    Electromagnetic Field Stimulation Therapy for Alzheimer’s Disease
- Review, AD, NA
*Aβ↓, *HSF1↑, *ROS↓, *Inflam↓, *cognitive↑, *memory↑, *eff↑,
3490- RF,    Multidimensional insights into the repeated electromagnetic field stimulation and biosystems interaction in aging and age-related diseases
- Review, AD, NA - Review, Park, NA
*OS↑, *memory↑, *cognitive↑, *memory↑, *Aβ↓, *eff↑, *HSF1↑, *HSP70/HSPA5↑,
4357- RF,    Targeted treatment of cancer with radiofrequency electromagnetic fields amplitude-modulated at tumor-specific frequencies
- Review, Var, NA
other↝, Dose↝, AntiTum↑, Ca+2↝, eff↝,
7149- Rhe,    Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells
- in-vitro, PC, NA
TumCCA↑, Casp↑, mt-Apoptosis↑, PI3K↓, Akt↓, ChemoSen↑, ROS↑, eff↓,
1749- RosA,    Rosmarinic Acid and Related Dietary Supplements: Potential Applications in the Prevention and Treatment of Cancer
- Review, Var, NA
antiOx↑, eff↑, *toxicity↝, *BioAv↑, *ROS↓, SOD↑, Catalase↑, GPx↑, lipid-P↓, P450↓, chemoP↑, hepatoP↑, ChemoSen↑,
1742- RosA,    Rosmarinic acid, a natural polyphenol, has a potential pro-oxidant risk via NADH-mediated oxidative DNA damage
- Analysis, Var, NA
ROS↑, Synergy↑, Synergy↑, eff↑, eff↑, eff↓, Dose↝, Dose↝,
1743- RosA,    New insights into the competition between antioxidant activities and pro-oxidant risks of rosmarinic acid
- Analysis, Var, NA
ROS↑, Fenton↑, eff↑, antiOx↑, Iron↓, ROS↑,
1744- RosA,    Therapeutic Applications of Rosmarinic Acid in Cancer-Chemotherapy-Associated Resistance and Toxicity
- Review, Var, NA
chemoR↓, ChemoSideEff↓, RadioS↑, ROS↓, ChemoSen↑, BioAv↑, Half-Life↝, antiOx↑, ROS↑, Fenton↑, DNAdam↑, Apoptosis↑, CSCs↓, HH↓, Bax:Bcl2↑, MDR1↓, P-gp/ABCB1↓, Synergy↑, eff↑, FOXO4↑, *eff↑, *ROS↓, *JNK↓, *ERK↓, *GSH↑, *H2O2↑, *MDA↓, *SOD↑, *HO-1↑, *CardioT↓, selectivity↑,
3021- RosA,    Rosmarinic acid ameliorates septic-associated mortality and lung injury in mice via GRP78/IRE1α/JNK pathway
- in-vivo, Sepsis, NA
*eff↑, *SOD↑, *MDA↓, *GRP78/BiP↓, *IRE1↓, *JNK↓, *Sepsis↓,
3005- RosA,    Nanoformulated rosemary extract impact on oral cancer: in vitro study
- in-vitro, Laryn, HEp2
TumCCA↑, ROS↑, Bcl-2↓, BAX↑, Casp3↑, P53↑, necrosis↑, eff↑, BioAv↑,
3002- RosA,    Anticancer Effects of Rosemary (Rosmarinus officinalis L.) Extract and Rosemary Extract Polyphenols
- Review, Var, NA
TumCG↓, TumCP↓, TumCCA↑, ChemoSen↑, NRF2↑, PERK↑, SESN2↑, HO-1↑, cl‑Casp3↑, ROS↑, UPR↑, ER Stress↑, CHOP/DDIT3↑, HER2/EBBR2↓, ER-α36↓, PSA↓, BAX↑, AR↓, P-gp/ABCB1↓, Cyt‑c↑, HSP70/HSPA5↑, eff↑, p‑Akt↓, p‑mTOR↓, p‑P70S6K↓, cl‑PARP↑, Synergy↑,
3034- RosA,  RES,  Ba,    The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells
- in-vitro, BC, MCF7
DNMTs↓, eff↑, eff↝,
7379- RS,    Blood pressure-lowering efficacy of reserpine for primary hypertension
- Review, Nor, NA
*BP↓, *Dose↓, eff↑,
7375- RS,    Regulation of hippo signaling mediated apoptosis by Rauvolfia tetraphylla in triple-negative breast cancer
- in-vitro, BC, MDA-MB-231
eff↝, TumCCA↑, TumCMig↓, ROS↑, BAX↑, Mst1↑, Bcl-2↓, YAP/TEAD↓, LATS1↓,
4899- Sal,    Anticancer activity of salinomycin quaternary phosphonium salts
- in-vitro, Var, NA
eff↑, selectivity↑, CSCs↓, TumCCA↑, MMP↓, ROS↑, mitResp↑,
4900- Sal,    Anticancer Mechanisms of Salinomycin in Breast Cancer and Its Clinical Applications
- Review, BC, NA
CSCs↓, Apoptosis↑, TumAuto↑, necrosis↑, TumCP↓, TumCI↓, TumCMig↓, TumCG↓, TumMeta↓, eff↑, Bcl-2↓, cMyc↓, Snail↓, ALDH↓, Myc↓, AR↓, ROS↑, NF-kB↓, PTCH1↓, Smo↓, Gli1↓, GLI2↓, Wnt↓, mTOR↓, GSK‐3β↓, cycD1/CCND1↓, survivin↓, P21↑, p27/CDKN1B↑, CHOP/DDIT3↑, Ca+2↑, DNAdam↑, Hif1a↓, VEGF↓, angioG↓, MMP↓, ATP↓, p‑P53↑, γH2AX↑, ChemoSen↑,
4902- Sal,  OXA,    Salinomycin and oxaliplatin synergistically enhances cytotoxic effect on human colorectal cancer cells in vitro and in vivo
- vitro+vivo, CRC, NA
RadioS↑, ChemoSen↑, TumCP↓, Apoptosis↑, ROS↑, MMP↓, MAPK↑, eff↓, TumCG↓, TumCCA↑,
5004- Sal,    Targeting Telomerase Enhances Cytotoxicity of Salinomycin in Cancer Cells
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
eff↑, AntiCan↑, CSCs↑, Wnt↓, β-catenin/ZEB1↓, Diff↑, ROS↑, toxicity↝, selectivity↝, eff↑,
5003- Sal,    Salinomycin, as an autophagy modulator-- a new avenue to anticancer: a review
- Review, Var, NA
CSCs↓, TumAuto↑, selectivity↑, DNAdam↑, TumCCA↑, P-gp/ABCB1↓, Wnt↓, β-catenin/ZEB1↓, RadioS↑, ChemoSen↑, Shh↓, eff↓, ROS↑, AMPK↑, JNK↑, ER Stress↑,
5000- Sal,    Salinomycin kills cancer stem cells by sequestering iron in lysosomes
- vitro+vivo, BC, NA
CSCsMark↓, eff↑, Ferroptosis↑, ROS↑,
4908- Sal,    Salinomycin triggers prostate cancer cell apoptosis by inducing oxidative and endoplasmic reticulum stress via suppressing Nrf2 signaling
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145
tumCV↓, ROS↑, lipid-P↑, UPR↑, ER Stress↑, NRF2↓, NADPH↓, HO-1↓, SOD↓, Catalase↓, GPx↓, eff↓, TumCP↓,

Showing Research Papers: 1151 to 1200 of 1416
Prev Page 24 of 29 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1416

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 21,   ARE/EpRE↑, 1,   Catalase↓, 12,   Catalase↑, 4,   Catalase∅, 1,   Copper↓, 1,   CoQ10↑, 1,   cystine↓, 1,   DJ-1↓, 1,   ENOX2↓, 2,   ENOX2↑, 1,   Fenton↑, 16,   GCLM↓, 1,   GPx↓, 8,   GPx↑, 5,   GPx1↓, 1,   GPx1↑, 1,   GPx4↓, 16,   GSH↓, 74,   GSH↑, 3,   GSH↝, 1,   GSH∅, 1,   i-GSH∅, 1,   mt-GSH↓, 1,   GSH/GSSG↓, 12,   GSR↓, 3,   GSSG↓, 1,   ox-GSSG↑, 1,   GSTs↓, 2,   GSTs↑, 2,   GSTs∅, 1,   H2O2?, 1,   H2O2↑, 17,   e-H2O2↓, 1,   i-H2O2↑, 1,   i-H2O2∅, 1,   mt-H2O2↑, 1,   HO-1↓, 8,   HO-1↑, 14,   HO-2↓, 1,   HO-2↑, 1,   hyperG↓, 1,   Iron↓, 1,   Iron↑, 11,   Iron↝, 2,   i-Iron↑, 2,   c-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 4,   lipid-P↑, 40,   MDA↓, 3,   MDA↑, 11,   MPO↓, 1,   NADH↑, 1,   NADHdeh?, 1,   NADPH/NADP+↓, 1,   NQO1↓, 2,   NQO1↑, 1,   Nrf1↑, 2,   NRF2↓, 17,   NRF2↑, 20,   NRF2↝, 3,   p‑NRF2↑, 1,   Prx↓, 1,   Prx3↑, 1,   Prx4↑, 1,   Prx6↑, 2,   PrxII↓, 1,   PYCR1↓, 1,   RNS↑, 2,   ROS?, 5,   ROS↓, 23,   ROS↑, 554,   ROS⇅, 7,   ROS↝, 5,   ROS∅, 1,   i-ROS↓, 1,   i-ROS↑, 6,   mt-ROS↑, 18,   RPM↑, 1,   SOD↓, 18,   SOD↑, 6,   mt-SOD↑, 1,   SOD1↓, 3,   SOD1↑, 2,   SOD2↓, 5,   SOD2↑, 4,   TAC↓, 3,   Thiols↓, 3,   i-Thiols↓, 1,   Trx↓, 6,   Trx↑, 1,   Trx1↓, 1,   ox-Trx1↑, 1,   Trx2↓, 1,   TrxR↓, 30,   TrxR↑, 1,   TrxR1↓, 10,   TrxR1↑, 1,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 6,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 5,   Ferritin↑, 1,   FTH1↓, 3,   IronCh↑, 4,   IRP1↑, 1,   Mets↑, 1,   NCOA4↑, 2,   Tf↓, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   CDC2↓, 3,   CDC25↓, 9,   CDC25↑, 2,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   compIII↑, 1,   EGF↓, 1,   ETC↓, 10,   ETC↝, 1,   HSP60/HSPD1↑, 1,   Insulin↓, 4,   MCU↓, 1,   mitResp↓, 8,   mitResp↑, 2,   MKK7↓, 1,   mtDam↑, 45,   OCR↓, 13,   OCR↑, 3,   mt-OCR↓, 1,   OXPHOS↓, 9,   OXPHOS↑, 6,   OXPHOS⇅, 1,   OXPHOS↝, 3,   mt-OXPHOS↑, 2,   PDH↓, 4,   PDH↑, 1,   p‑PDH↓, 1,   PGC-1α↑, 4,   PINK1↑, 4,   SDH↓, 3,   SIRT3↓, 1,   SIRT3↑, 1,   TrxR2↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 3,   5LO↓, 4,   ACC↓, 2,   ACC↑, 1,   p‑ACC↑, 1,   ACLY↓, 7,   p‑ACLY↓, 1,   ACSL4↑, 2,   adiP↑, 2,   ADO↓, 1,   ALAT↓, 2,   ALAT∅, 1,   ALDOA↓, 2,   AMP↑, 1,   AMPK↑, 25,   AMPK↝, 1,   p‑AMPK↑, 3,   ATP↓, 43,   ATP↑, 1,   ATP∅, 1,   i-ATP↓, 1,   i-ATP↑, 1,   Buty↑, 2,   CAIX/CA9↓, 2,   citrate↓, 1,   CPT1A↓, 1,   CRM↑, 1,   CRM↝, 1,   ECAR↓, 6,   ECAR↝, 1,   ENO1↓, 3,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 3,   FASN↑, 2,   FBPase↑, 1,   GAPDH↓, 3,   GLS↓, 1,   glucoNG↑, 1,   glucose↓, 2,   glucose↑, 1,   glucose∅, 1,   GlucoseCon↓, 15,   GlucoseCon↑, 2,   GlucoseCon∅, 1,   glut↓, 1,   glyC↓, 1,   Glycolysis↓, 51,   Glycolysis↑, 3,   Glycolysis↝, 1,   GSK‐3β↓, 10,   GSK‐3β↑, 4,   p‑GSK‐3β↓, 4,   p‑GSK‐3β↑, 1,   Histones↑, 1,   HK1↓, 1,   HK2?, 1,   HK2↓, 24,   HK2↑, 1,   HK2∅, 1,   HMG-CoA↓, 3,   KeyT↑, 1,   lactateProd↓, 26,   lactateProd↑, 4,   lactateProd∅, 1,   e-lactateProd↓, 1,   LDHA↓, 12,   LDHA↑, 1,   LDHA∅, 1,   LDL↓, 4,   lipidLev↓, 1,   lipidLev↑, 1,   lipoGen↓, 1,   MCT4↓, 1,   NAD↓, 2,   NADPH↓, 8,   NADPH↑, 1,   NH3↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 9,   PDKs↓, 4,   PFK↓, 6,   PFK1↓, 2,   PFK2?, 1,   PFK2↓, 1,   PFKP↓, 2,   PGK1↓, 2,   PGM1↓, 1,   PGM1∅, 1,   PKM2↓, 20,   p‑PKM2↓, 1,   polyA↓, 1,   PPP↓, 2,   PPP↑, 1,   Pyruv↓, 1,   SCD1↓, 3,   SCFAs↑, 2,   SIRT1↓, 9,   SIRT1↑, 6,   SREBP1/SREBF1↓, 2,   SREBP2↓, 1,   TCA?, 1,   TCA↓, 2,   TCA↑, 2,   TCA↝, 1,   TS↓, 3,   UGDH↓, 2,   Warburg↓, 11,   Warburg↑, 1,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 18,   APAF1↑, 5,   Apoptosis?, 1,   Apoptosis↓, 12,   Apoptosis↑, 357,   mt-Apoptosis↑, 6,   ASC↓, 1,   ASK1↑, 2,   p‑ASK1↑, 1,   aSmase↑, 1,   BAD↓, 1,   BAD↑, 10,   Bak↓, 1,   Bak↑, 11,   BAX↓, 6,   BAX↑, 145,   Bax:Bcl2↑, 38,   Bcl-2↓, 155,   Bcl-2↑, 4,   Bcl-2∅, 1,   Bcl-xL↓, 38,   Bcl-xL↑, 3,   BID↓, 1,   BID↑, 7,   p‑BID↓, 1,   cl‑BID↑, 2,   BIM↑, 7,   BNIP3?, 2,   BNIP3↑, 1,   BNIP3↝, 1,   Casp↓, 1,   Casp↑, 55,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp12?, 1,   Casp12↑, 2,   pro‑Casp12↓, 1,   Casp2↑, 3,   Casp3↓, 4,   Casp3↑, 176,   cl‑Casp3↑, 51,   cl‑Casp3∅, 1,   proCasp3↓, 3,   proCasp3↑, 3,   CASP4↑, 1,   Casp6↑, 1,   Casp7↑, 20,   cl‑Casp7↑, 5,   Casp8↓, 2,   Casp8↑, 41,   Casp8∅, 2,   cl‑Casp8↑, 4,   proCasp8↑, 2,   Casp9↓, 1,   Casp9↑, 105,   cl‑Casp9↓, 1,   cl‑Casp9↑, 20,   proCasp9↓, 1,   proCasp9↑, 2,   cFLIP↓, 5,   Cupro↑, 3,   Cyt‑c↓, 1,   Cyt‑c↑, 121,   Cyt‑c↝, 1,   Diablo↑, 5,   DIDO1/DIO-1↑, 1,   DR5↑, 23,   Endon↑, 1,   FADD↑, 5,   Fap1↓, 1,   Fas↓, 2,   Fas↑, 15,   FasL↓, 1,   FasL↑, 13,   FasL⇅, 1,   Ferroptosis↓, 4,   Ferroptosis↑, 30,   GranB/GZMB↑, 1,   GranB/GZMB↝, 1,   GSDMD↑, 3,   GSDME↑, 1,   cl‑GSDME↑, 1,   GSDME-N↑, 2,   IAP1↓, 7,   IAP2/BIRC3↓, 3,   ICD↑, 5,   iNOS↓, 9,   iNOS↑, 1,   Mcl-1↓, 24,   p‑Mcl-1↓, 1,   cl‑Mcl-1↑, 1,   MDM2↓, 13,   MDM2↑, 1,   p‑MDM2↓, 1,   MLKL↑, 3,   p‑MLKL↓, 1,   MOMP↓, 2,   MOMP↑, 5,   Necroptosis↑, 7,   necrosis↑, 10,   NOXA↑, 6,   p38↓, 3,   p38↑, 25,   p‑p38↓, 1,   p‑p38↑, 12,   Paraptosis↑, 4,   Perforin↑, 1,   Perforin↝, 1,   PUMA↑, 7,   Pyro↑, 9,   RIP1↓, 2,   RIP1↑, 2,   RIP3↑, 3,   p‑RIP3↑, 2,   SK↓, 1,   survivin↓, 50,   TRAIL↑, 5,   TumCD↓, 4,   TumCD↑, 55,   TumCD∅, 2,   TUNEL↑, 1,   XIAP↓, 22,   YAP/TEAD↓, 7,   YAP/TEAD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 1,   Akt↓, 115,   Akt↑, 6,   p‑Akt↓, 37,   p‑Akt↑, 4,   AKT1↓, 2,   AMPKα↑, 4,   BRAF↓, 1,   CaMKII ↓, 2,   CaMKII ↑, 1,   CK2↓, 2,   cMET↓, 2,   CREB↑, 1,   cSrc↓, 1,   DDIT4↑, 1,   EGFR↓, 24,   EGFR↑, 2,   p‑EGFR↓, 1,   ERK↓, 32,   ERK↑, 12,   p‑ERK↓, 12,   p‑ERK↑, 8,   e-ERK↑, 1,   FOXD3↑, 1,   HCAR2↑, 1,   HER2/EBBR2↓, 8,   HGF/c-Met↓, 1,   Hippo↓, 2,   Hippo↝, 1,   IGF-1R↓, 2,   IGFR↓, 2,   IKKα↓, 7,   IKKα↑, 3,   p‑IKKα↓, 1,   IκB↑, 2,   p‑IκB↓, 2,   JAK↓, 2,   JAK1?, 1,   JAK1↓, 1,   p‑JAK1↓, 1,   JAK2↓, 8,   p‑JAK2↓, 5,   JNK↓, 6,   JNK↑, 33,   p‑JNK↑, 13,   LATS1↓, 1,   MAPK↓, 22,   MAPK↑, 16,   p‑MAPK↓, 1,   p‑MAPK↑, 6,   MEK↓, 2,   p‑MEK↓, 2,   p‑MEK↑, 1,   MKK4↓, 1,   MKP1↓, 1,   MKP2↓, 1,   Mst1↑, 1,   mTOR↓, 59,   mTOR↑, 3,   mTOR⇅, 1,   mTOR↝, 1,   p‑mTOR↓, 12,   mTORC2↓, 1,   mTORC2↑, 1,   p70S6↓, 2,   P70S6K↓, 2,   p‑P70S6K↓, 2,   p85S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 82,   PI3K↑, 5,   p‑PI3K↓, 4,   PI3K/Akt↓, 1,   PIK3CA↓, 1,   PIK3CA↑, 1,   PKA↓, 3,   PKA↑, 1,   PKCδ↓, 5,   PTEN↓, 1,   PTEN↑, 15,   p‑PTEN↓, 1,   Raf↓, 3,   RAS↓, 4,   p‑RSK↑, 1,   p‑S6K↓, 1,   Sp1/3/4↓, 7,   Src↓, 2,   p‑Src↓, 2,   STAT↓, 4,   STAT3↓, 54,   STAT3↑, 3,   STAT3⇅, 1,   STAT3↝, 1,   p‑STAT3↓, 15,   p‑STAT3↑, 2,   mt-STAT3↓, 1,   STAT6↓, 2,   p‑STAT6↓, 1,   p‑STK11/LKB1↑, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF3↑, 1,   ATF4↑, 10,   ATF4↝, 1,   CBP↓, 1,   ChrMod↑, 1,   cJun↓, 2,   cJun↑, 3,   p‑cJun↑, 1,   cMyc↓, 31,   cMyc↑, 1,   DNMT1↓, 4,   DNMT1↑, 1,   DNMT3A↓, 1,   DNMTs↓, 5,   EZH2↓, 1,   FOXO1↑, 2,   FOXO3↓, 2,   FOXO3↑, 5,   FOXO4↑, 2,   H3↓, 3,   p‑H3↓, 1,   p‑H3↑, 1,   ac‑H3↓, 1,   ac‑H3↑, 2,   H3K27ac∅, 1,   H4↓, 1,   ac‑H4↓, 1,   ac‑H4↑, 1,   HATs↓, 1,   HATs↑, 1,   HDAC↓, 26,   HDAC1↓, 4,   HDAC10↓, 1,   HDAC10↑, 1,   HDAC2↓, 1,   HDAC3↓, 2,   HDAC8↓, 2,   IRF1↑, 1,   KLF2↓, 1,   KLF5↓, 1,   miR-124-3p↓, 1,   miR-129-5p↑, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 1,   miR-155↓, 1,   miR-199↓, 1,   miR-200b↑, 1,   miR-200c↑, 1,   miR-203↑, 1,   miR-21↓, 1,   miR-218↑, 1,   miR-22↑, 1,   miR-29b↑, 1,   miR-30a-5p↑, 2,   miR-375↑, 1,   miR-490↑, 1,   Myc↓, 5,   n-MYC↓, 1,   NDRG1↑, 1,   OCT4↓, 10,   other?, 4,   other↓, 8,   other↑, 18,   other↝, 63,   other∅, 2,   PhotoS↑, 3,   SD↑, 1,   SETBP1↓, 1,   sonoS↑, 2,   SOX2↓, 7,   SOX4↑, 1,   SOX9↓, 1,   SUV39H↓, 3,   TCF-4↓, 1,   TFE3↑, 2,   tumCV?, 1,   tumCV↓, 113,   tumCV↑, 3,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 33,   e-CRT↑, 1,   EDEM↑, 1,   eIF2α↓, 1,   eIF2α↑, 6,   p‑eIF2α↓, 1,   p‑eIF2α↑, 8,   ER Stress↓, 2,   ER Stress↑, 80,   ER Stress↝, 1,   ERStress↑, 1,   GRP78/BiP?, 1,   GRP78/BiP↓, 5,   GRP78/BiP↑, 18,   HSF1↓, 1,   HSP27↓, 1,   HSP27↑, 1,   HSP70/HSPA5↓, 6,   HSP70/HSPA5↑, 4,   e-HSP70/HSPA5↑, 1,   HSP90↓, 13,   HSP90↑, 2,   e-HSP90↑, 2,   ac‑HSP90↑, 1,   HSPs↑, 2,   HSPs∅, 1,   IRE1↑, 4,   NPL4↓, 2,   PERK↑, 9,   p‑PERK↓, 1,   p‑PERK↑, 1,   Proteasome↓, 4,   PSMB5↓, 1,   UPR↓, 1,   UPR↑, 14,   mt-UPR↑, 1,   XBP-1↑, 6,   XBP-1↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

APA↑, 1,   ATG3↓, 1,   ATG5↑, 5,   ATG7↑, 1,   Beclin-1/ATG6↓, 2,   Beclin-1/ATG6↑, 14,   p‑Beclin-1/ATG6↑, 1,   LAMP1?, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 3,   LC3B↑, 3,   LC3B-II↑, 5,   LC3II↑, 19,   LC3s↑, 2,   lysoMP↓, 1,   lysoMP↑, 1,   MitoP↑, 3,   p62↓, 11,   p62↑, 6,   p‑p62↑, 1,   PARK2↑, 4,   SESN2↑, 3,   TFEB↑, 1,   TumAuto↓, 5,   TumAuto↑, 75,   TumAuto↝, 1,   mt-TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↓, 1,   ATM↑, 5,   ATR↑, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   BRCA2↓, 3,   DNA-PK↑, 2,   DNAdam↓, 5,   DNAdam↑, 97,   mt-DNAdam↑, 1,   DNArepair↓, 3,   hTERT/TERT↓, 7,   MDMX↓, 1,   NKX3.1↓, 2,   p16↑, 3,   P53↓, 6,   P53↑, 72,   P53↝, 3,   P53∅, 1,   p‑P53↑, 6,   p53 Wildtype↓, 1,   PARP↓, 6,   PARP↑, 16,   p‑PARP↑, 1,   cl‑PARP↑, 103,   cl‑PARP∅, 1,   proPARP↓, 1,   cl‑PARP1↑, 4,   PCNA↓, 12,   SIRT6↓, 2,   SIRT6↑, 1,   Telomerase↓, 16,   TOP1↓, 4,   TOP1↑, 1,   TOP1↝, 1,   TOP2↓, 2,   TOP2↑, 2,   TP53↓, 2,   TRF2↓, 1,   UHRF1↓, 1,   γH2AX↑, 12,   p‑γH2AX↑, 5,  

Cell Cycle & Senescence(tgid=11) ⓘ

ANAPC2↑, 1,   AURKB↑, 1,   CDK1?, 1,   CDK1↓, 11,   p‑CDK1↓, 1,   p‑CDK1↑, 1,   CDK2↓, 20,   CDK4↓, 31,   CDK4↑, 3,   p‑CDK4↓, 1,   CDK6↓, 11,   CDK6↑, 5,   CDK8↓, 1,   CDKN2C/p18↑, 1,   cellSen↑, 1,   CHK1↓, 1,   Chk2↑, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 8,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 22,   CycB/CCNB1↑, 5,   cycD1/CCND1↓, 56,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   CycD3↓, 2,   CycD3↑, 1,   cycE/CCNE↓, 13,   cycE/CCNE↑, 1,   cycF↑, 1,   E2Fs↓, 1,   GADD45A↑, 2,   Ki-67↓, 26,   mitA↓, 1,   mitA↑, 1,   p19↑, 1,   P21↓, 3,   P21↑, 57,   p27/CDKN1B↑, 22,   PLK1↓, 1,   RB1↑, 2,   p‑RB1↓, 4,   TubPol↓, 1,   TumCCA?, 1,   TumCCA↓, 6,   TumCCA↑, 228,   UBE2C↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 9,   ALDH1A1↓, 4,   BMI1↓, 3,   CD133↓, 9,   CD24↓, 3,   CD34↓, 1,   cFos↓, 2,   cFos↑, 1,   cMYB↓, 1,   CSCs↓, 48,   CSCs↑, 2,   CSCsMark↓, 1,   Diff↓, 1,   Diff↑, 4,   FGF↓, 2,   Gli↓, 1,   Gli1↓, 6,   HH↓, 8,   HMGCR↓, 1,   IGF-1?, 1,   IGF-1↓, 18,   IGF-1↑, 1,   IGF-1↝, 1,   IGF-1∅, 1,   IGF-2↓, 1,   IGFBP1↓, 1,   IGFBP1↑, 3,   IGFBP3↑, 3,   Ki-67↓, 26,   Let-7↑, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 10,   Nestin↓, 1,   NOTCH↓, 4,   NOTCH↑, 1,   NOTCH1↓, 5,   NOTCH1↑, 1,   NOTCH3↓, 1,   p300↓, 1,   Piezo1↑, 1,   PTCH1↓, 2,   Shh↓, 4,   Smo↓, 4,   STAT1↓, 1,   TumCG?, 1,   TumCG↓, 161,   TumCG↑, 5,   TumCG↝, 2,   TumCG∅, 1,   TumCP↓, 211,   TumCP↑, 7,   TumCP∅, 3,   Wnt?, 1,   Wnt↓, 27,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

Alix/AIP‑1↓, 1,   AntiAg↑, 2,   AP-1↓, 7,   ATPase↓, 1,   ATPase↑, 1,   AXL↓, 3,   BACH1↑, 1,   CA↓, 1,   Ca+2↓, 8,   Ca+2↑, 45,   Ca+2↝, 5,   i-Ca+2?, 1,   i-Ca+2↓, 1,   i-Ca+2↑, 3,   CAFs/TAFs↓, 2,   Cdc42↓, 2,   Cdc42↑, 1,   Chl↑, 1,   Chl∅, 1,   CTNNB1↓, 1,   E-cadherin↓, 3,   E-cadherin↑, 25,   EMT↓, 44,   EMT↑, 1,   EpCAM↓, 1,   F-actin↓, 1,   FAK↓, 10,   p‑FAK↓, 2,   p‑FAK↑, 1,   FOSB↑, 1,   GLI2↓, 3,   hnRNPA1↓, 1,   ITGA1∅, 1,   ITGA5∅, 1,   ITGB1↓, 1,   ITGB1∅, 1,   ITGB3↓, 1,   ITGB3∅, 1,   ITGB4∅, 1,   KRAS↓, 2,   LEF1↓, 2,   LRP1↓, 1,   MALAT1↓, 1,   MET↓, 2,   p‑MET↓, 1,   MMP1↓, 6,   MMP13↓, 1,   MMP2↓, 52,   MMP2↑, 1,   MMP2∅, 1,   proMMP2↓, 1,   MMP3↓, 3,   MMP7↓, 4,   MMP9↓, 60,   MMP9↑, 2,   MMP9∅, 1,   MMPs↓, 20,   MTA1↓, 1,   MUC1↑, 1,   N-cadherin↓, 9,   N-cadherin↑, 1,   NEDD9↓, 1,   p‑p44↓, 1,   PAK1↓, 3,   PAK1↑, 1,   PDGF↓, 3,   Rac1↓, 1,   Rho↓, 5,   ROCK1↓, 2,   Slug↓, 4,   Smad1↓, 1,   SMAD3↓, 2,   Snail?, 1,   Snail↓, 16,   SPARC↑, 1,   TET1?, 1,   TET1↑, 2,   TGF-β↓, 5,   TGF-β1↓, 2,   TIMP1↓, 1,   TIMP1↑, 2,   TIMP2↓, 1,   TIMP2↑, 6,   TRIB3↑, 1,   TSC1↑, 1,   TSP-1↑, 2,   TumCA↓, 2,   TumCI?, 1,   TumCI↓, 62,   TumCI↑, 1,   TumCMig↓, 66,   TumCMig↑, 2,   TumMeta↓, 62,   TumMeta↑, 5,   TumPF↓, 1,   Twist↓, 10,   TXNIP↑, 1,   Tyro3↓, 1,   uPA↓, 9,   uPAR↓, 2,   Vim↓, 16,   Vim↑, 1,   Zeb1↓, 8,   ZEB2↓, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 39,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 91,   angioG↑, 4,   angioG∅, 1,   CD31/PECAM-1↓, 1,   EGR1↑, 1,   Endoglin↑, 1,   eNOS↑, 1,   HIF-1↓, 1,   Hif1a↓, 48,   Hif1a↑, 3,   Hypoxia↓, 1,   LOX1↓, 1,   NO↓, 1,   NO↑, 8,   PHDs↓, 1,   VCAM-1↓, 2,   VEGF↓, 65,   VEGFR1↓, 3,   VEGFR2/KDR/Flk1↓, 5,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 2,   BBB↑, 8,   BBB∅, 1,   CellMemb↓, 1,   CellMemb↑, 6,   CLDN1↓, 2,   CLDN1↑, 1,   CLDN2↓, 1,   CLDN2↑, 1,   CTR1↑, 1,   EPR↓, 1,   EPR↑, 19,   EPR↝, 1,   GLUT1↓, 15,   GLUT1↑, 1,   GLUT2↓, 1,   GLUT3↓, 2,   GLUT4↓, 3,   IBI↑, 2,   KCNH2/hERG↓, 1,   LAT↓, 1,   MMP?, 1,   MMP↓, 198,   MMP↑, 1,   MPT↑, 11,   NHE1↓, 2,   OATPs↓, 1,   OCLN↑, 1,   SLC12A5↓, 2,   SMCT1∅, 1,   sonoP↑, 2,   TJ↓, 1,   TJ↑, 1,   TRPM7↓, 2,   TRPV1↑, 5,   VGCC↑, 1,   VGSC↑, 1,   ZO-1↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD14↓, 1,   CD4+↓, 1,   CD4+↑, 2,   CD44↓, 12,   CD47↓, 1,   CD8+↑, 9,   cDC2↓, 4,   cGAS–STING↑, 1,   COX1↓, 2,   COX2/PTGS2↓, 48,   COX2/PTGS2↑, 5,   CR3↝, 1,   CXCR2↓, 1,   CXCR4↓, 11,   DCells↑, 1,   Dectin1↝, 1,   DR4↑, 6,   DR4∅, 1,   DR6↑, 1,   Eos↑, 1,   Gal1↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   e-HMGB1↑, 1,   ICAM-1↓, 3,   IFN-γ↓, 1,   IFN-γ↑, 5,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 3,   IL1↑, 2,   IL10↓, 3,   IL10↑, 2,   IL12↓, 1,   IL12↑, 1,   IL17↑, 1,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 12,   IL1β↑, 1,   IL2↓, 2,   IL2↑, 6,   IL4↓, 3,   IL6↓, 25,   IL6↑, 1,   IL7↓, 1,   IL8↓, 6,   IL8↑, 1,   Imm↑, 36,   Imm↝, 3,   Inflam↓, 33,   Inflam↑, 1,   IRAK4↓, 1,   pol-M1↑, 1,   pol-M1↝, 1,   M2 MC↓, 3,   pol-M2 MC↓, 1,   MCP1/CCL2↓, 3,   MIP2↓, 1,   Neut↓, 1,   NF-kB↓, 105,   NF-kB↑, 5,   p‑NF-kB↓, 1,   p‑NF-kB↑, 1,   NK cell↑, 15,   NLRP3↓, 2,   NLRP3↑, 3,   p50↓, 1,   p65↓, 7,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 12,   PD-L1↑, 4,   PDT+↓, 1,   PGE2↓, 13,   PSA↓, 13,   RANTES↓, 1,   SOCS1↑, 1,   T-Cell↑, 2,   T-Cell↝, 1,   TCF↓, 3,   TCF↝, 1,   TLR1↑, 1,   TLR2↓, 1,   TLR4↓, 5,   TNF-α↓, 19,   TNF-α↑, 2,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRAF1↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

ADAM17↓, 1,   GFAP↓, 1,   pH↑, 7,   pH↝, 2,   pH∅, 1,   e-pH↓, 1,   e-pH↑, 6,   i-pH↓, 1,   TAMS↑, 1,   Temp↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

6IL↑, 1,   ACTH↓, 1,   AR↓, 19,   AR↑, 1,   AR↝, 1,   AR-FL↓, 1,   AR-V7↑, 1,   CYP11A1↓, 1,   CYP19↓, 1,   CYP24A1↓, 1,   ER-α36↓, 1,   ER(estro)↓, 2,   Estro↝, 1,   FKBP5↓, 1,   GR↓, 1,   Leptin↓, 1,   PPARα↓, 1,   PPARγ↓, 1,   PPARγ↑, 3,   RANKL↓, 1,   SRC3↓, 1,   SXR↑, 1,   VDR↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCC2↓, 1,   BioAv↓, 49,   BioAv↑, 64,   BioAv↝, 12,   BioEnh?, 1,   BioEnh↑, 10,   CBR1↓, 1,   chemoR↓, 2,   ChemoSen?, 1,   ChemoSen↓, 6,   ChemoSen↑, 209,   ChemoSen↝, 1,   CompStab↓, 3,   CompStab↑, 4,   CompStab↝, 1,   CYP1A1↓, 2,   CYP1A1↑, 1,   DDS↑, 10,   Dose?, 16,   Dose↓, 8,   Dose↑, 22,   Dose⇅, 1,   Dose↝, 153,   Dose∅, 29,   DrugR↓, 1,   eff?, 5,   eff↓, 440,   eff↑, 816,   eff⇅, 4,   eff↝, 143,   eff∅, 26,   GSTA1↓, 2,   GSTZ1↓, 1,   GSTZ1↝, 1,   GSTZ1∅, 1,   Half-Life↓, 16,   Half-Life↑, 9,   Half-Life↝, 13,   Half-Life∅, 1,   MDR1↓, 6,   MRP↓, 2,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 21,   P-gp/ABCB1∅, 1,   P450↓, 2,   RadioS↓, 1,   RadioS↑, 81,   RadioS↝, 1,   RadioS∅, 1,   selectivity?, 2,   selectivity↓, 3,   selectivity↑, 199,   selectivity↝, 1,   selectivity∅, 2,   Synergy↑, 132,   Synergy∅, 1,   TET2↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AFP?, 1,   AFP↓, 3,   ALAT↓, 2,   ALAT∅, 1,   ALB∅, 1,   ALP↓, 2,   AR↓, 19,   AR↑, 1,   AR↝, 1,   ascitic↓, 1,   AST↓, 2,   AST∅, 1,   BG↓, 6,   BMD↑, 2,   BP↓, 1,   BRAF↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CA125↓, 1,   CA125∅, 1,   CA19-9↓, 1,   CEA↓, 3,   CRP↓, 2,   CRP∅, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 24,   EGFR↑, 2,   p‑EGFR↓, 1,   EZH2↓, 1,   Ferritin↓, 5,   Ferritin↑, 1,   Hcy/homoC↓, 4,   Hcy/homoC↝, 1,   HER2/EBBR2↓, 8,   HOMA↓, 1,   hTERT/TERT↓, 7,   IL6↓, 25,   IL6↑, 1,   KeyT↑, 1,   KRAS↓, 2,   LDH?, 1,   LDH↓, 8,   LDH↑, 4,   LDH↝, 1,   i-LDH↓, 1,   Myc↓, 5,   NOS2↑, 1,   NSE↓, 1,   PD-L1↓, 12,   PD-L1↑, 4,   PSA↓, 13,   TP53↓, 2,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiCan↓, 3,   AntiCan↑, 80,   AntiCan∅, 1,   AntiDiabetic↑, 1,   antiNeop↑, 4,   AntiTum↓, 3,   AntiTum↑, 34,   AntiTum⇅, 1,   cachexia↓, 2,   cardioP↑, 10,   CardioT↓, 1,   CardioT↑, 2,   CardioT↝, 1,   chemoP↑, 40,   chemoP↝, 1,   chemoPv↑, 19,   ChemoSideEff↓, 15,   cognitive↑, 5,   fatigue↓, 3,   hepatoP↓, 1,   hepatoP↑, 8,   memory↑, 2,   motorD↑, 1,   Mucositis↓, 1,   MusCon↓, 2,   neuroP↑, 7,   NKG2D↑, 1,   NP/CIPN↓, 1,   NP/CIPN↑, 2,   OS?, 2,   OS↑, 65,   OS↝, 1,   OS∅, 1,   PARP16↓, 1,   PFS?, 1,   PFS↑, 3,   QoL↑, 12,   QoL∅, 3,   radioP↑, 20,   radioP↝, 1,   Remission↑, 4,   RenoP↑, 4,   Risk↓, 35,   Risk↑, 1,   Risk∅, 4,   Sleep↑, 1,   Strength∅, 1,   toxicity↓, 51,   toxicity↑, 8,   toxicity⇅, 1,   toxicity↝, 25,   toxicity∅, 7,   TumVol↓, 58,   TumW↓, 29,   Weight↓, 1,   Weight↑, 7,   Weight∅, 5,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiP↑, 2,   Bacteria↓, 4,   Dectin1↝, 1,   GutMicro↑, 13,   GutMicro↝, 3,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 4,  
Total Targets: 1244

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 10,   antiOx↑, 99,   mt-antiOx↑, 1,   ARE↑, 2,   Bil↓, 1,   Catalase↓, 1,   Catalase↑, 37,   Copper↓, 1,   CoQ10↑, 1,   DPPH↓, 1,   Fenton↓, 3,   GPx↑, 26,   GPx1↑, 1,   GPx4↓, 1,   GPx4↑, 3,   GPx4∅, 1,   GSH↓, 3,   GSH↑, 48,   GSR↑, 4,   GSTs↑, 8,   H2O2↓, 5,   H2O2↑, 1,   HDL↓, 1,   HDL↑, 5,   HDL∅, 2,   HO-1?, 1,   HO-1↓, 1,   HO-1↑, 28,   HO-1↝, 1,   HO-1∅, 1,   hyperG↓, 1,   Iron↓, 3,   Keap1↓, 2,   Keap1↑, 1,   lipid-P↓, 33,   lipid-P↑, 1,   mt-lipid-P↓, 1,   MDA↓, 30,   MDA↑, 1,   MDA∅, 1,   MPO↓, 5,   MPO↑, 1,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 7,   Nrf1↑, 1,   NRF2↓, 4,   NRF2↑, 51,   NRF2⇅, 1,   NRF2∅, 1,   Prx↑, 1,   RNS↓, 5,   ROS?, 4,   ROS↓, 133,   ROS↑, 14,   ROS⇅, 3,   ROS↝, 1,   ROS∅, 7,   mt-ROS↓, 1,   mt-ROS↑, 2,   selenoP↑, 4,   SOD↓, 3,   SOD↑, 59,   SOD1↑, 2,   TAC↑, 7,   TBARS↓, 4,   Trx↑, 2,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 4,   VitE↓, 1,   VitE↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FPN↑, 1,   IronCh↑, 6,   IronCh↝, 1,   Mets↝, 1,   NCOA4↝, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   compII↑, 1,   compIII↓, 1,   compIII↑, 1,   DRP1/DNM1L↑, 1,   ETC↓, 1,   ETC↑, 1,   FIS1↓, 1,   FIS1↑, 1,   Insulin↓, 3,   Insulin↑, 1,   mitResp↑, 2,   mtDam↓, 6,   OCR↑, 1,   mt-OCR↑, 1,   OXPHOS↑, 1,   PGC-1α↑, 4,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12-HETE↓, 1,   12LOX↓, 3,   5-HETE↓, 1,   5LO↓, 3,   ACSL4∅, 1,   adiP↓, 1,   adiP↑, 2,   ALAT↓, 15,   ALAT∅, 1,   AMPK↓, 1,   AMPK↑, 6,   ATP↓, 3,   ATP↑, 9,   BHB↑, 1,   cAMP↑, 2,   DHA↑, 1,   ECAR↓, 1,   ECAR↑, 1,   Eic↓, 1,   mt-FAO↑, 1,   glucose↓, 4,   glucose↑, 1,   GlucoseCon↑, 4,   Glycolysis↓, 1,   GSK‐3β↓, 4,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   p‑GSK‐3β↑, 1,   KeyT↑, 4,   lactateProd↓, 1,   LDL↓, 14,   lipidLev↓, 1,   NAD↑, 1,   NADH:NAD↑, 1,   NADPH↓, 2,   NADPH↑, 3,   PKM2↓, 2,   SCD1↓, 1,   SIRT1↓, 1,   SIRT1↑, 8,   SIRT2↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 15,   Apoptosis∅, 2,   ASK1↓, 1,   BAX↓, 6,   BAX↑, 2,   Bax:Bcl2↓, 2,   Bcl-2↓, 2,   Bcl-2↑, 3,   Bcl-2∅, 1,   Bcl-xL↓, 1,   Bcl-xL↑, 1,   Casp12↓, 2,   Casp3↓, 16,   Casp3↑, 2,   Casp3∅, 1,   cl‑Casp3↓, 2,   cl‑Casp8↑, 1,   Casp9↓, 6,   Casp9↑, 1,   Cyt‑c↓, 5,   Cyt‑c↑, 3,   Cyt‑c∅, 3,   Ferroptosis↓, 4,   GranB/GZMB↓, 1,   HEY1↑, 1,   iNOS↓, 13,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 1,   p38↑, 2,   p‑p38↓, 1,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 7,   e-Akt↑, 1,   AKT1↓, 1,   Akt2↓, 1,   AMPKα↑, 1,   CREB↑, 1,   ERK↓, 1,   ERK↑, 4,   e-ERK↑, 1,   HCAR2↑, 1,   IKKα↓, 1,   IκB?, 1,   JAK2↑, 1,   JNK↓, 4,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 7,   MAPK↑, 6,   Mst1↓, 1,   mTOR↓, 5,   mTOR↑, 1,   mTOR↝, 1,   p‑mTOR↓, 1,   p‑mTOR↑, 1,   PI3K↓, 4,   PI3K↑, 4,   PKA↑, 2,   PKCδ?, 1,   PKCδ↓, 1,   PKCδ↑, 1,   PP2A↑, 1,   PTEN↓, 2,   RAS↓, 1,   STAT↓, 1,   STAT3↓, 3,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 4,   ATF4↓, 1,   FOXO↑, 1,   HDAC↓, 1,   other?, 4,   other↓, 9,   other↑, 27,   other↝, 44,   SOX9↑, 1,   tumCV↓, 1,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   cl‑eIF2α↑, 1,   ER Stress↓, 6,   ER Stress↑, 1,   GRP78/BiP↓, 4,   GRP78/BiP↑, 1,   HSF1↑, 2,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 2,   HSP70/HSPA5↝, 1,   HSPs↑, 3,   IRE1↓, 2,   p‑PERK↑, 1,   UPR↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

CTSZ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   MitoP↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 13,   DNAdam↑, 2,   DNArepair↑, 3,   P53↑, 2,   PARP↓, 1,   γH2AX↓, 1,   p‑γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   E2Fs↑, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   Choline↑, 1,   Diff↑, 4,   Diff↝, 1,   FGF↑, 1,   IGF-1↓, 2,   IGFBP3↑, 1,   neuroG↑, 1,   NOTCH↑, 1,   TumCP↓, 2,   tyrosinase↓, 1,   Wnt↑, 2,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 12,   ARG1/2↑, 1,   Ca+2↓, 3,   Ca+2↑, 7,   Ca+2↝, 4,   cal2↓, 1,   Cartilage↑, 1,   COL1↓, 1,   COL2A1↑, 1,   E-cadherin↑, 1,   EMT↓, 2,   EMT↑, 1,   F-actin↑, 1,   FAK↑, 2,   MLC2/MYL9↝, 1,   MMP13↓, 1,   MMP2↓, 2,   MMP2↑, 2,   MMP9↓, 11,   MMP9↑, 2,   MMPs↓, 1,   MMPs↑, 1,   PAI-1/SERPINE1↓, 1,   SMAD3↓, 2,   Snail↑, 1,   TG2/TGase↓, 1,   TGF-β↓, 1,   TGF-β↑, 4,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   Twist↑, 1,   Vim↓, 1,   Vim↑, 1,   α-SMA↓, 1,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 2,   CD31/PECAM-1↑, 1,   eNOS↑, 1,   Hif1a↓, 2,   Hif1a↑, 2,   Hif1a∅, 1,   NO?, 1,   NO↓, 13,   NO↑, 4,   VCAM-1↓, 2,   VEGF↓, 2,   VEGF↑, 5,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 38,   BBB↝, 1,   BBB∅, 2,   CellMemb↑, 1,   CLDN1↓, 1,   CLDN1↑, 1,   CLDN1↝, 1,   EPR↑, 1,   GastroP↑, 5,   GLUT1↑, 2,   GLUT3↑, 1,   GLUT4↑, 1,   IBI↑, 1,   ketosis↑, 1,   MMP↓, 4,   MMP↑, 10,   MMP↝, 1,   MMP∅, 2,   MPT↑, 1,   OCLN↝, 1,   TJ↓, 1,   TJ↑, 2,   TRPV3↑, 1,   VGCC↑, 2,   VGCC⇅, 1,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 1,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD14↑, 1,   CD25+↑, 1,   CD4+↑, 3,   CD8+↑, 2,   COX1↓, 4,   COX2/PTGS2↓, 22,   CXCR4↓, 1,   Eos↓, 1,   FOXP3↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   IFN-γ↓, 3,   IFN-γ↑, 2,   IgE↓, 1,   IL1↓, 2,   IL10?, 1,   IL10↓, 2,   IL10↑, 9,   IL10∅, 1,   IL17↓, 7,   IL17∅, 1,   IL18↓, 1,   IL1α↓, 1,   IL1β↓, 26,   IL2↓, 2,   IL22↓, 1,   IL23↓, 1,   IL4↓, 1,   IL4↑, 3,   IL4∅, 1,   IL5↑, 1,   IL6↓, 33,   IL6↑, 4,   IL8↓, 3,   Imm↑, 18,   Imm⇅, 1,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 130,   Inflam↑, 2,   IRF3↓, 1,   LPS↓, 2,   M2 MC↑, 1,   MCP1/CCL2↓, 4,   MCP1/CCL2↑, 1,   MIP‑1α/CCL3↓, 1,   MyD88↓, 2,   NeuroI↓, 1,   NF-kB↓, 31,   NF-kB↑, 2,   NK cell↑, 1,   NLRP3↓, 5,   NLRP3↑, 1,   p65↓, 1,   PAF↓, 1,   PGE2↓, 9,   PSA↓, 1,   TLR1↓, 1,   TLR2↓, 2,   TLR4↓, 4,   TNF-α↓, 48,   TNF-α↑, 1,   Treg lymp↑, 1,   Treg lymp↝, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,   Temp↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 1,   5HT↓, 1,   5HT↑, 2,   Ach?, 1,   Ach↑, 6,   AChE↓, 24,   AChE∅, 2,   ADAM10↑, 1,   BChE↓, 9,   BDNF↑, 15,   BrainVol↑, 1,   BrainVol∅, 1,   ChAT↑, 1,   GABA↑, 3,   MAOA↓, 2,   NMDAR↑, 1,   PSD95↑, 1,   SNAP25↑, 1,   TrkB↑, 1,   β-Endo↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   APP↓, 4,   Aβ↓, 32,   Aβ42↓, 1,   BACE/β-secretase↓, 8,   IDE↑, 1,   tau↓, 4,   p‑tau↓, 8,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

BNP↓, 1,   GPER↑, 1,   GR↑, 2,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv?, 1,   BioAv↓, 36,   BioAv↑, 66,   BioAv⇅, 1,   BioAv↝, 24,   BioAv∅, 1,   BioEnh↑, 8,   ChemoSen↑, 1,   CompStab↓, 1,   CompStab↑, 5,   CompStab↝, 2,   CYP1A1↓, 1,   CYP2C19↓, 1,   CYP2C8↓, 1,   CYP2C9↓, 1,   CYP2D6↓, 1,   CYP2E1↓, 1,   CYP3A4↓, 2,   DDS↑, 1,   Dose?, 2,   Dose↓, 8,   Dose↑, 7,   Dose⇅, 1,   Dose↝, 93,   Dose∅, 2,   eff?, 2,   eff↓, 37,   eff↑, 264,   eff↝, 36,   eff∅, 2,   GSTA1↓, 2,   GSTA1↑, 1,   Half-Life↓, 5,   Half-Life↑, 7,   Half-Life⇅, 1,   Half-Life↝, 14,   Half-Life∅, 4,   P-gp/ABCB1↓, 3,   P450↓, 1,   selectivity↑, 2,   Synergy↑, 13,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 15,   ALAT∅, 1,   ALP↓, 4,   ALP↑, 1,   anemia↓, 1,   AST↓, 15,   AST∅, 1,   BG↓, 1,   Bil↓, 1,   BloodF↑, 3,   BMD↑, 7,   BP↓, 16,   BP∅, 1,   BUN↓, 3,   creat↓, 6,   CRP↓, 7,   Ferritin↓, 1,   FEV1↑, 2,   Hcy/homoC↓, 2,   HemoG↑, 1,   hs-CRP↓, 1,   IL6↓, 33,   IL6↑, 4,   KeyT↑, 4,   LDH↓, 6,   LDH↑, 1,   LDH∅, 1,   NLR↓, 1,   NOS2↓, 2,   PEF↑, 1,   PSA↓, 1,   PV↓, 1,   RBC↑, 1,   SpO2↑, 1,   TC↓, 1,   TMAO↑, 3,   TMAO⇅, 1,   UFR?, 1,   UFR↑, 1,   UR↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 5,   antiAll↑, 15,   antiAll∅, 1,   AntiArt↑, 7,   AntiCan↑, 11,   antiD↓, 1,   AntiDiabetic↑, 18,   antiPs↑, 1,   AntiTum↓, 1,   AntiTum↑, 3,   BOLD↑, 2,   Bone Healing↑, 1,   cachexia↓, 1,   cardioP↑, 37,   CardioT↓, 3,   chemoP↑, 10,   chemoPv↑, 5,   cognitive?, 1,   cognitive↓, 3,   cognitive↑, 71,   cognitive∅, 1,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 1,   hepatoP↑, 31,   IPSS↝, 1,   Learn↑, 1,   memory↓, 2,   memory↑, 41,   memory∅, 1,   Mood?, 1,   Mood↑, 5,   motorD↓, 1,   motorD↑, 13,   MusCon↓, 1,   Nausea↓, 1,   neuroP?, 1,   neuroP↑, 73,   Obesity↓, 8,   OS↓, 1,   OS↑, 5,   Pain↓, 9,   PDE4↓, 1,   QoL↑, 1,   radioP↑, 4,   RenoP↑, 15,   Risk↓, 8,   Risk↑, 2,   Sleep↑, 5,   Strength↑, 2,   Stress↓, 3,   Stroke↓, 8,   toxicity?, 3,   toxicity↓, 78,   toxicity↑, 7,   toxicity↝, 11,   toxicity∅, 27,   Vomit↓, 1,   Weight↓, 4,   Weight↑, 1,   Weight↝, 1,   Weight∅, 1,   Wound Healing↓, 1,   Wound Healing↑, 11,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 7,   AntiFungal↑, 4,   AntiP↓, 1,   AntiP↑, 2,   AntiViral↑, 13,   Bacteria↓, 26,   Diar↓, 1,   Dysb↓, 1,   GutMicro↑, 15,   GutMicro↝, 1,   Inf↓, 1,   Sepsis↓, 7,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 2,   Ingr↝, 5,   Phen↑, 1,  
Total Targets: 612

Scientific Paper Hit Count for: eff, efficacy
64 Silver-NanoParticles
59 Magnetic Fields
33 Sulforaphane (mainly Broccoli)
28 Thymoquinone
27 Curcumin
26 immunotherapy
26 Shikonin
25 Chemotherapy
25 Vitamin C (Ascorbic Acid)
23 chitosan
22 Selenite (Sodium)
21 Radiotherapy/Radiation
21 Baicalein
21 Selenium NanoParticles
20 Piperlongumine
19 Copper and Cu NanoParticles
19 EGCG (Epigallocatechin Gallate)
18 Artemisinin
17 Magnetic Field Rotating
16 Melatonin
16 Berberine
16 Exercise
15 Chlorogenic acid
14 Apigenin (mainly Parsley)
14 Luteolin
14 Phenylbutyrate
14 Caffeic acid
14 Capsaicin
14 Resveratrol
14 Quercetin
14 Gambogic Acid
13 Selenium
13 diet FMD Fasting Mimicking Diet
12 Gold NanoParticles
12 Citric Acid
12 Ashwagandha(Withaferin A)
12 Propolis -bee glue
12 Folic Acid, Vit B9
12 Dichloroacetate
12 Hydrogen Gas
11 3-bromopyruvate
11 Cisplatin
11 Betulinic acid
11 Ivermectin
11 Lycopene
11 Phenethyl isothiocyanate
10 Vitamin D3
10 Choline
10 diet Methionine-Restricted Diet
10 Disulfiram
10 Honokiol
9 Auranofin
9 Metformin
9 borneol
9 Electrical Pulses
9 Formononetin
9 Bicarbonate(Sodium)
8 Photodynamic Therapy
8 Fenbendazole
8 SonoDynamic Therapy UltraSound
8 chaetocin
8 doxorubicin
8 Fisetin
8 Hyperthermia
8 Plumbagin
8 Rosmarinic acid
7 Coenzyme Q10
7 Docetaxel
7 Boron
7 buckwheat sprouts
7 Ellagic acid
7 Chrysin
7 Dandelion Root
7 Juglone
7 VitK3,menadione
7 mebendazole
7 salinomycin
6 Alpha-Lipoic-Acid
6 beta-glucans
6 isoorientin
6 Carnosic acid
6 Celastrol
6 Vitamin B12
6 Chlorophyllin
6 Docosahexaenoic Acid
6 Eugenol
6 MCT oil
6 Flaxseed/Linseed
6 Ginger/6-Shogaol/Gingerol
6 isoquercitrin
6 MCT, metronomic chemo
6 Parthenolide
6 Vitamin K2
5 Astragalus
5 Akkermansia
5 Bevacizumab (brand Avastin)
5 Ascorbyl Palmitate
5 Lutein
5 Bifidobacterium
5 Boswellia (frankincense)
5 Piperine
5 Silymarin (Milk Thistle) silibinin
5 Cynaropicrin
5 Diclofenac
5 eicosapentaenoic acid
5 diet Plant based
5 Lemongrass Extract/Citral
5 Ginkgo biloba-EGb 761
5 Gossypol/AT-101
5 Isoliquiritigenin
5 Licochalcone A
5 Moringa oleifera
5 Nimbolide
5 Spermidine
5 Urolithin
4 chemodynamic therapy
4 EMF
4 Cynara scolymus/Globe Artichoke/Artichoke Extract
4 Allicin (mainly Garlic)
4 almonertinib
4 Berbamine
4 α-Bisabolol / Chamomile oil
4 Butyrate
4 capecitabine
4 Carvacrol
4 Cat’s Claw
4 Centella asiatica / Gotu kola → asiaticoside
4 CUSP9
4 diet Short Term Fasting
4 Echinacea
4 Kaempferol
4 phytic acid, Inositol hexakisphosphate
4 Fucoidan
4 Ginkgolide B
4 Ginseng
4 HydroxyCitric Acid
4 Magnolol
4 Isobavachalcone
4 Matrine
4 methylseleninic acid
4 Methylsulfonylmethane
4 Propyl gallate
4 Pterostilbene
4 Terpinen-4-ol / Tea Tree Oil
4 Whole Body Vibration
3 cetuximab
3 5-fluorouracil
3 Anthocyanins
3 Aspirin
3 Atorvastatin
3 Aloe anthraquinones
3 bempedoic acid
3 beta-carotene(VitA)
3 Zeaxanthin
3 Bortezomib
3 Bullatacin
3 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
3 Thymol-Thymus vulgaris
3 Cannabidiol
3 Chocolate
3 Cichoric acid / Chicoric acid
3 Crocetin
3 Cysteamine
3 erastin
3 Gallic acid
3 Gamma-aminobutyric acid
3 Ginkgo biloba
3 Lemon Balm/Melissa officinalis
3 Germanium Organic/Ge-132 / propagermanium (organogermanium)
3 Gemcitabine (Gemzar)
3 Hibiscus sabdariffa
3 HydroxyTyrosol
3 iodine
3 Inulin Prebiotic
3 isoflavones
3 Licorice
3 Lactoferrin/Talactoferrin
3 nicotinamide adenine dinucleotide
3 Radio Frequency
3 Sulfasalazine
3 Taurine
3 Vitamin B1/Thiamine
2 1,8-Cineole
2 2-DeoxyGlucose
2 Glucose
2 Zinc
2 Andrographis
2 Anti-oxidants
2 Vitamin A, Retinoic Acid
2 Aromatherapy
2 Astaxanthin
2 Arsenic trioxide
2 Baicalin
2 Huperzine A/Huperzia serrata
2 Beta-Caryophyllene
2 Bufalin/Huachansu
2 temozolomide
2 probiotics
2 brusatol
2 Vitexin
2 Isovitexin
2 Rutin
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Caffeine
2 Calcium
2 Celecoxib
2 Hydroxycinnamic-acid
2 Calorie Restriction Mimetics
2 Cyclopamine
2 Dichloroacetophenone(2,2-)
2 Deguelin
2 Date Fruit Extract
2 diet Ketogenic
2 Oxygen, Hyperbaric
2 D-limonene
2 statins
2 Emodin
2 Vitamin E
2 ferumoxytol
2 Paclitaxel/Taxol
2 SDG/lignans
2 tamoxifen
2 Garcinol
2 Geldanamycin
2 γ-linolenic acid (Borage Oil)
2 Grapeseed extract
2 Orlistat
2 hydroxychloroquine
2 Helleborus niger extracts – Christmas Rose
2 Hyperoside
2 itraconazole
2 Potassium
2 lambertianic acid
2 Lapachol
2 Methylene blue
2 Methyl Jasmonate
2 Magnesium
2 Mistletoe/Viscum album Extracts
2 Naringin
2 Marjoram (Origanum majorana)
2 Rauwolfia serpentina/Indian Snakeroot
2 Aflavin-3,3′-digallate
2 tetrathiomolybdate
2 Ursolic acid
1 5-Aminolevulinic acid
1 Anzaroot, Astragalus fasciculifolius Bioss
1 wortmannin
1 Resiquimod
1 Aidi injection
1 Acetyl-l-carnitine
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Amodiaquine
1 DTS(dibenzyl trisulphide) from Anamu
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Sorafenib (brand name Nexavar)
1 Trastuzumab
1 Biochanin A
1 Brucea javanica
1 Bacopa monnieri
1 Bromelain
1 Bruteridin(bergamot juice)
1 urea
1 Cannabichromene
1 Beta‐Lapachone
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 irinotecan
1 Carvone
1 Polyphenols
1 Black phosphorus
1 Cucurbitacin
1 gefitinib, erlotinib
1 Dasatinib/Phyrago
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 Dipyridamole
1 Protocatechuic acid
1 PXD, phenoxodiol
1 Eurycomanone
1 flavonoids
1 Flickering Light Stimulation
1 Flaxseed Oil
1 Galloflavin
1 verapamil
1 Salvia officinalis
1 Germanium inorganic
1 Geraniol
1 Germanium-Spirogermanium
1 Ginkgetin
1 Glabrescione B
1 Graviola
1 High-Ozonide Oil
1 Indole-3-carbinol
1 entinostat
1 Recombinant Methioninase
1 Lactobacillus
1 Laetrile B17 Amygdalin
1 Lapatinib
1 low dose naltrexone
1 Lecithin
1 Linalool
1 Mung Bean Sprouts
1 Modified Citrus Pectin
1 carboplatin
1 Methylglyoxal
1 magnetic nanoparticles
1 Mushroom Lion’s Mane
1 Mushroom Reishi
1 Myricetin
1 No Product/Mechanism Only
1 Oleocanthal
1 Peppermint
1 sericin
1 Phosphatidylserine
1 Pumpkin Seed Oil / Cucurbita pepo
1 Tamsulosin
1 enzalutamide
1 Rhein
1 Oxaliplatin
1 α-Santalol/Sandalwood oil
1 Scoulerine
1 polyethylene glycol
1 Iron
1 Squalene
1 Glutathione
1 Sutherlandioside D
1 Triphala
1 triptolide
1 Tumor Treating Fields
1 Turmerones
1 Vitamin B3,Niacin
1 Vitamin B5,Pantothenic Acid
1 Vitamin B6,pyridoxine
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page