Ferroptosis Cancer Research Results

Ferroptosis, Ferroptosis: Click to Expand ⟱
Source:
Type: type of cell death
Type of programmed cell death dependent on iron.
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides to lethal levels. It is distinct from other forms of cell death, such as apoptosis, necrosis, and autophagy. The process of ferroptosis is heavily dependent on iron metabolism and reactive oxygen species (ROS).
The accumulation of lipid peroxides is a hallmark of ferroptosis. This can occur when the antioxidant defenses, such as glutathione and selenoproteins, are overwhelmed or inhibited. Many cancer cells upregulate GPX4 to evade ferroptosis, making it a potential target for therapy. It has been described that GPX4, xCT and ACSL-4 are the main targets in the regulation of ferroptosis.
Scientific Papers found: Click to Expand⟱
7871- isoO,  Cisplatin,    Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway
- vitro+vivo, Lung, NA
ChemoSen↑, i-Iron↑, i-MDA↑, *i-ROS↑, GSH↓, Ferroptosis↑, NRF2↓, GPx4↓, SIRT6↓,
7812- ISQ,    Isoquercitrin promotes ferroptosis and oxidative stress in nasopharyngeal carcinoma via the AMPK/NF-κB pathway
- vitro+vivo, NPC, CNE1 - in-vitro, NPC, HNE1
tumCV↓, TumCP↓, ROS↑, lipid-P↑, NF-kB↓, MAPK↓, IL1β↓, TumCG↓, lipid-P↓, Ferroptosis↓, eff↓,
7810- ISQ,    Isoquercitrin Inhibits Lung Cancer Cell Growth Through Triggering Pyroptosis and Ferroptosis
- vitro+vivo, Lung, A549 - in-vitro, Nor, BEAS-2B
tumCV↓, selectivity↑, Apoptosis↑, NLRP3↑, Pyro↑, Ferroptosis↑, ROS↑, eff↓, Dose↝, TumCG↓,
9230- ITCs,  AITC,  BITC,  PEITC,  SFN  Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death
- Review, Var, NA
Ferroptosis↑, Ingr↝, GSH↓, ROS↑, lipid-P↑, MDA↑, GPx4↓, Iron↑, xCT/SLC7A11↓,
5099- JG,    Juglone induces ferroptosis in glioblastoma cells by inhibiting the Nrf2-GPX4 axis through the phosphorylation of p38MAPK
- vitro+vivo, GBM, LN229 - vitro+vivo, GBM, T98G
Ferroptosis↑, p‑MAPK↑, NRF2↓, GPx4↓, TumPF↓, Apoptosis↑, ROS↑, GSH↓, lipid-P↑, Ki-67↓, TumCG↓,
1921- JG,    Juglone induces ferroptotic effect on hepatocellular carcinoma and pan-cancer via the FOSL1-HMOX1 axis
- in-vitro, PC, NA - vitro+vivo, PC, NA
TumCG↓, Ferroptosis↑, ROS↑, Iron↑, lipid-P↑, MDA↑, GSH↓, FOSL1↑, HO-1↑,
8071- KAE,    Cellular reprogramming and signaling control by kaempferol in colorectal cancer
- Review, CRC, NA
*toxicity↓, Risk↓, MMPs↓, VEGF↓, VEGFR1↓, Wnt↓, β-catenin/ZEB1↑, PI3K↓, Akt↓, mTOR↓, ChemoSen↑, *BioAv↓, TumCCA↑, Apoptosis↑, Hif1a↓, ROS↑, TumCMig↓, TumMeta↓, PKM2↓, Glycolysis↓, DNAdam↑, HO-1↑, Ferroptosis↑, eff↑, Dose↝, BioAv↑,
8073- KAE,    Kaempferol inhibits oxidative stress-induced ferroptosis via the ROS/P38MAPK pathway to delay intervertebral disc degeneration: a combinatorial study of cell, animal, and transcriptomic evidence
- Review, Nor, NA
*Inflam↓, *antiOx↑, *ROS↓, *MAPK↓, *Ferroptosis↓,
8054- KAE,    Kaempferol Improves Alzheimer's Disease by Inhibiting Neuronal Ferroptosis via Activating GPX4/AKR1C3 Signaling Pathway
- vitro+vivo, AD, NA
*AKR1B10↝, *MDA↓, *ROS↓, *GSH↑, *SOD↑, *GPx4↑, *NQO1↑, *xCT/SLC7A11↑, *NRF2↑, *HO-1↑, *cognitive↑, *Aβ↓, *p‑tau↓, *Ferroptosis↓, *AKR1C3/17β-HSD5/PGF Synthase↑, *AKR1B1/ALR2↑,
8055- KAE,    Molecular Mechanisms of the Anticancer Activity of the Flavonoid Kaempferol: A Comprehensive Review
- Review, Var, NA
antiNeop↑, *toxicity↓, TumCCA↑, ROS↑, ER Stress↑, TumAuto↑, Pyro↑, Ferroptosis↑, angioG↓, Imm↝, Synergy↑, ChemoSen↑, MPT↑, MMP↓, mtDam↑, Cyt‑c↑, Bax:Bcl2↑, Fas↑, DR4↑, DR5↑, JNK↑, ERK↑, CHOP/DDIT3↑, ER Stress↑, UPR↑, Ca+2↑, PI3K↓, Akt↓, mTOR↓, AMPK↑, *Ferroptosis↓, *antiOx↑, *NRF2↑, *GPx4↑, *ROS↓, *MDA↓, *i-Iron↓, *xCT/SLC7A11↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓, EMT↓, STAT3↓, M2 MC↓, MCP1/CCL2↓, MMP9↓, MMP2↓, TIMP2↓, ChemoSen↑, PKM2↑, Glycolysis↓, CSCs↓, SOX4↓, OCT4↓, CD44↓, Nanog↓, MDR1↓, *GutMicro↑,
8112- LA,    Metabolomics and proteomics reveal the inhibitory effect of Lactobacillus crispatus on cervical cancer
- in-vitro, Cerv, SiHa
HO-1↝, ACSL4↝, Ferroptosis↑, T-cadherin↑, ROS↑, lipid-P↑,
8260- LCA,    Licochalcone A Induces Ferroptosis in Hepatocellular Carcinoma via Reactive Oxygen Species Activated by the SLC7A11/GPX4 Pathway
- vitro+vivo, Liver, HepG2 - in-vitro, Liver, HUH7
tumCV↑, xCT/SLC7A11↓, Ferroptosis↑, GPx4↑, ROS↑, TumCP↓, TumCD↑, Iron↑,
8214- LCA,    Licochalcone A decreases cancer cell proliferation and enhances ferroptosis in acute myeloid leukemia through suppressing the IGF2BP3/MDM2 cascade
- vitro+vivo, AML, U937
TumCP↓, Ferroptosis↑, IGF2BP3/IMP3/KOC↓, MDM2↓,
8225- LCA,  Cisplatin,    Licochalcone A protects against cisplatin-induced acute kidney injury via the modulation of Nrf2/Keap1-mediated ferroptosis and apoptosis
- in-vivo, Nor, NA
*RenoP↑, *Urea↓, *BUN↓, *creat↓, *Apoptosis↓, *Ferroptosis↓, *Iron↓, *ROS↓, *lipid-P↓, *mtDam↓, *NRF2↑,
8135- LF,    Lactoferrin-A Regulator of Iron Homeostasis and Its Implications in Cancer
- Review, Var, NA - Review, AD, NA
IronCh↑, ROS↓, Imm↑, Inflam↓, *BBB↑, Iron↝, *Fenton↓, *ROS↓, *TAC↑, *SOD↑, *GPx↑, *GSH↑, *TBARS↓, *PTEN↓, *tau↓, *MAPK↓, *Aβ42↓, *Apoptosis↓, *Casp3↓, *Akt↑, *GutMicro↑, *Sepsis↓, *anemia↓, *IL6↓, *FPN↑, *TfR1/CD71↑, *Ferritin↓, *HemoG↑, *RBC↑, *eff↑, *BioAv↓, *BioAv↑, *BioAv↝, *ChemoSen↑, *BioAv↑, Ferroptosis↑,
8139- LF,    Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis
- vitro+vivo, Pca, NA
Ferroptosis↓, AR↝, Iron↝, Ferritin↑, P53↓, eff↝, other↝, AntiTum↓,
8375- LT,    Luteolin, a flavone ingredient: Anticancer mechanisms, combined medication strategy, pharmacokinetics, clinical trials, and pharmaceutical researches
- Review, Var, NA
TumCP↓, TumCI↓, Apoptosis↑, TumCCA↑, Inflam↓, Ferroptosis↑, Pyro↑, ChemoSen↑, chemoP↑, *BioAv↓, OATPs↓,
8379- LT,    Luteolin and neuroinflammation: a multi-target therapeutic strategy for central nervous system disorders
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*neuroP↑, *Inflam↓, *ROS↓, *Apoptosis↓, *BioAv↓, *BBB∅, Ferroptosis↑, ROS↑, Iron↑, lipid-P↑, MDA↑, GSH↓, GPx4↓, *Aβ↓, *memory↑, *neuroG↑, *NRF2↑, *NLRP3↓, *ROS↓, JAK2↓, STAT3↓, PD-L1↓, Perforin↝, GranB/GZMB↝, hepatoP↑, *Learn↑, *TNF-α↓, *IL1β↓, *IL6↓, *NO↓, *COX2/PTGS2↓, *iNOS↓, *ER Stress↓, *GRP78/BiP↓, *IRE1↓, *cognitive↑, *BAX↓, *Bcl-2↓, *Casp3↓, *PSD95↑, *SNAP25↑, *JNK↓, *eff↑, *mtDam↓, *MMP↑, *Stroke↓, *TJ↑, *MMP9↓, *BBB∅, *NeuroI↓,
8370- LT,    Luteolin Induces GPX4-dependent Ferroptosis and Enhances Immune Activation in Colon Cancer
- vitro+vivo, Colon, NA
TumCP↓, ROS↑, Iron↑, lipid-P↑, MDA↑, GSH↓, GPx4↓, Ferroptosis↑, pol-M1↑, CD8+↑, Imm↑,
8384- LT,    Current situation and research progress of luteolin in the treatment of gastrointestinal malignant tumors
- Review, GC, NA
Apoptosis↑, TumAuto↑, TumCCA↑, EMT↓, *ROS↓, *antiOx↑, ROS↑, P53↑, LC3II↑, Beclin-1/ATG6↑, p‑MAP2K1/MEK1↓, p‑ERK↓, BAX↑, cl‑Casp3↑, Bcl-2↓, p‑MAPK↓, DNArepair↓, HMGB1↓, XRCC1↓, ERCC3↑, CycB/CCNB1↓, CDC2↓, p‑CHK1↑, TumCCA↑, TumCP?, Wnt↓, β-catenin/ZEB1↓, miR-384↑, PTN↓, MMP2↓, MMP3↓, MMP9↓, MMP16↓, Ferroptosis↑, GPx4↓, Synergy↑, Ki-67↓, GSH↓, ChemoSen↑, TumCP↓, TumCMig↓, TumCI↓, PI3K↓, Akt↓, mTOR↓, NF-kB↓, NOTCH↓, miR-139-5p↑, miR-34a↑, miR-422a↑, miR-107↑, miR-21↓, miR-155↓, miR-224↓, miR-340↓, E-cadherin↑, N-cadherin↓, Vim↓, HK1↓, FOXO1↓, compI↓, compIII↓, compV↓, ETC↓, BioAv↝,
8389- LT,    Luteolin-Manganese Nanozyme Induces Apoptosis and Ferroptosis for Enhanced Cancer Therapy
- in-vitro, Var, NA
ROS↑, Apoptosis↑, cl‑Casp3↑, cl‑Casp9↑, Ferroptosis↑, NRF2↓, GPx4↓, IronCh↑,
1275- LT,    Mechanism of luteolin induces ferroptosis in nasopharyngeal carcinoma cells
- in-vitro, Laryn, NA
Ferroptosis↑, MDA↑, Iron↑, SOD↓, GSH↓, GPx4↓, SOX4↓, GDF15↓,
8541- Matr,    Matrine induces ferroptosis and suppresses colorectal cancer through targeting the STAT3/SLC7A11 pathway
- in-vivo, CRC, NA
TumCP↓, necrosis↑, Ferroptosis↑, TumCD↑, lipid-P↑, MDA↑, GSH↓, xCT/SLC7A11↓, P53↑, p‑STAT3↓,
8535- Matr,    Matrine induces ferroptosis in cervical cancer through activation of piezo1 channel
- in-vitro, Cerv, NA
TumCG↓, *toxicity↓, Ferroptosis↑, GPx4↓, lipid-P↑, Iron↓, ROS↑, Piezo1↑,
8529- Matr,    Matrine targets β-catenin and blocks the formation of β-catenin/TCF7L2 complex to promote ferroptosis and inhibit metastasis in triple-negative breast cancer
- in-vitro, BC, NA
β-catenin/ZEB1↓, Wnt↓, TCF7/TCF1↓, GPx4↝, Ferroptosis↑, EMT↓,
8549- Matr,    Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis
- in-vitro, Var, NA
toxicity↑, *hepatoP↓, *SOD↓, *GSH↓, *MDA↑, *ROS↑, *lipid-P↑, *Iron↝, *Ferroptosis↑, *FTH1↓, *NRF2↓, *xCT/SLC7A11↓, *GPx4↓, *HO-1↓, *toxicity↝,
8547- Matr,    Matrine in cancer therapy: antitumor mechanisms and nano-delivery strategies
- Review, Var, NA
*Ingr↝, *AntiTum↑, Apoptosis↑, TumAuto↑, Ferroptosis↑, TumCP↓, TumCMig↓, TumCI↓, JPT1/HN1↓, Erlin1↑, LINC01116↓, miR-592↑, ERK↓, JAK↓, STAT3↓, miR-182-5p↓, PI3K↓, Akt↓, Wnt↓, β-catenin/ZEB1↓, Sharpin↓, ROS↓, AMPK↑, mTOR↓, Snail↓, Vim↓, N-cadherin↓, MMP2↓, MMP9↓, E-cadherin↑, PTEN↑, miR-10b-5p↓, GPx4↓, lipid-P↑, Iron↑, Piezo1↑,
8546- Matr,    Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice
- in-vivo, Stroke, NA
*Dose?, *Stroke↓, *BBB↝, *TJ↑, *ZO-1↑, *OCLN↑, *CLDN4↑, *HMGB1↓, *RAGE↓, *JNK↓, *p38↓, *ERK↓, *NF-kB↓, *IL1β↓, *IL6↓, *TNF-α↓, *BAX↓, *Bcl-2↑, *Apoptosis↓, *Iron↓, *ACSL4↓, *GPx4↑, *Ferroptosis↓, *neuroP↑, *Inflam↓, *antiOx↑,
8545- Matr,    Matrine enhances RLS3-induced ferroptosis at non-toxic doses in acute myeloid leukemia cells with MLL rearrangement
- in-vitro, AML, MV411 - in-vitro, ALL, MOLM-13
Ferroptosis↑, Synergy↑, i-Iron↑, ROS↑, MMP↓, GSH↓, xCT/SLC7A11↓, GPx4↓, P53↑,
8625- MCT,    Medium-Chain Fatty Acids Selectively Sensitize Cancer Cells to Ferroptosis by Inducing CD36 and ACSL4
- in-vitro, lymphoma, U937 - in-vitro, Lung, A549
Ferroptosis↑, ACSL4↑, CD36/FAT↑,
8483- MF,    Magnetic Fields in Cancer Therapy: Mechanistic Insights, Signaling Pathways, and Evidence from Clinical and In Vitro Studies
- Review, Var, NA
Apoptosis↑, TumCP↓, Ferroptosis↑, TumCMig↓, EMT↓, ROS↝, ChemoSen↑, RadioS↑, Telomerase↓, selectivity↑, ROS↑, DNAdam↑, Casp↑, Ca+2↑, MMP↓, lysoMP↑, lipid-P↑, NA↑, other↑, ChemoSen↑, P53↑,
8489- MF,    Pulsed electromagnetic fields induce ferroptosis in osteosarcoma cells and promote osteogenic differentiation
- in-vitro, OS, U2OS - in-vitro, OS, MG63
TumCP↓, TumCMig↓, Ferroptosis↑, GPx4↓, xCT/SLC7A11↓, BMD↑, selectivity↑, Dose↝, TumCG↓, Dose↝, OS↑, ROS↑, MDA↑, Iron↑, ChemoSen↑, TOP2↑, radioP↑,
8482- MFrot,    Polyhedral magnetic nanoparticles induce apoptosis in gastric cancer stem cells and suppressing tumor growth through magnetic force generation
- vitro+vivo, GC, NA
*Apoptosis↑, *Ferroptosis↑, *Dose?, *CellMemb↑, *tumCV↓, *TumCG↓,
8479- MFrot,  doxoR,    Dual-targeting by rotating magnetic field-driven superparamagnetic bionic nanorobots for enhanced triple-negative breast cancer therapy
- vitro+vivo, BC, 4T1
Dose?, EPR↑, BioEnh↑, GSH↓, GPx4↓, Iron↑, ROS↑, lipid-P↑, Ferroptosis↑, TumVol↓, Fenton↑,
582- MNPs,  immuno,  VitC,    Magnetic field boosted ferroptosis-like cell death and responsive MRI using hybrid vesicles for cancer immunotherapy
- in-vitro, Pca, TRAMP-C1 - in-vivo, NA, NA
Fenton↑, Ferroptosis↑, ROS↑, TumCG↓, Iron↑, GPx4↓,
8873- MOR,  Zeo,    Targeting Ferroptosis/Nrf2 Pathway Ameliorates AlCl3-Induced Alzheimer's Disease in Rats: Neuroprotective Effect of Morin Hydrate, Zeolite Clinoptilolite, and Physical Plus Mental Activities
- in-vivo, AD, NA
*neuroP↑, *p‑tau↓, *antiOx↑, *Ferroptosis↓, *NRF2↑, *Learn↑, *memory↑, *AChE↓, *HO-1?, *SOD↑, *TAC↑, *GPx4↑, *Synergy↑, *TLR4↓, *BAX↓, *Bcl-2↑, *BDNF↑, *Wnt↑, *β-catenin/ZEB1↑, *APP↓, *BACE/β-secretase↓,
8882- MOR,  Cisplatin,    Morin hydrate protects against cisplatin-induced testicular toxicity by modulating ferroptosis and steroidogenesis genes' expression and upregulating Nrf2/Heme oxygenase-1
- in-vivo, Nor, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose?, *SOD↑, *GPx↑, *NRF2↑, *HO-1↑, *MDA↓, *other↑, *Ferroptosis↓, *Iron↓, *ROS↓, *other↓, ChemoSen↑, *chemoP↑, *selectivity↑,
1273- Myr,    Myricetin Induces Ferroptosis and Inhibits Gastric Cancer Progression by Targeting NOX4
- vitro+vivo, GC, NA
Ferroptosis↑, MDA↑, Iron↑, GSH↓, NOX4↑, NRF2↓, GPx4↓,
2937- NAD,    High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1-AMPK-ACC Pathway
- in-vitro, Lung, A549
SIRT1↑, Dose↝, TumCP⇅, Ferroptosis↑, lipid-P↑, AMPK↑, ACC↑,
1225- OLST,    Orlistat Induces Ferroptosis in Pancreatic Neuroendocrine Tumors by Inactivating the MAPK Pathway
- vitro+vivo, PC, NA
TumCMig↓, TumCI↓, Ferroptosis↑, MAPK↓,
9044- PatchO,    Patchouli oil and its main component patchouli alcohol inhibit colorectal cancer by activating ectopic olfactory receptor
- vitro+vivo, CRC, HCT116
OS↑, TumCG↓, Inflam↓, AMPK↑, Ferroptosis↑, OR13G1?, CaMKII ?, TumPF↓, TumCMig↓, Tumccf↓,
2054- PB,    Sodium butyrate induces ferroptosis in endometrial cancer cells via the RBM3/SLC7A11 axis
- in-vitro, EC, ISH - in-vitro, EC, HEC1B
Ferroptosis↑, xCT/SLC7A11↓, RBM3↑, HDAC↓, ROS↑,
4925- PEITC,    PEITC triggers multiple forms of cell death by GSH-iron-ROS regulation in K7M2 murine osteosarcoma cells
- in-vitro, OS, NA
tumCV↓, TumCP↓, TumCCA↑, GSH↓, ROS↑, Ferroptosis↑, Apoptosis↑, TumAuto↑, MAPK↑, TumCG↓, Dose⇅,
4927- PEITC,    Targeting ferroptosis in osteosarcoma
- Review, OS, NA
AntiCan↑, BioAv↑, Ferroptosis↑, TfR1/CD71↑, Iron↑, ROS↑, MDA↑, lipid-P↑, GPx4↓,
2958- PL,    Natural product piperlongumine inhibits proliferation of oral squamous carcinoma cells by inducing ferroptosis and inhibiting intracellular antioxidant capacity
- in-vitro, Oral, HSC3
TumCP↓, lipid-P↑, ROS↑, DNMT1↑, FTH1↓, GPx4↓, eff↓, GSH↓, Ferroptosis↑, MDA↓,
2956- PL,    Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis
- in-vitro, PC, NA
ROS↑, Ferroptosis↓, GSH↓, GPx↓, cl‑PARP∅, cl‑Casp3∅, eff↑, eff↑,
2954- PL,    The metabolites from traditional Chinese medicine targeting ferroptosis for cancer therapy
- Review, Var, NA
NRF2↑, ROS↑, ER Stress↑, MAPK↑, CHOP/DDIT3↑, selectivity↑, Keap1↝, HO-1↑, Ferroptosis↑,
4965- PSO,  Cisplatin,    The synergistic antitumor effects of psoralidin and cisplatin in gastric cancer by inducing ACSL4-mediated ferroptosis
- vitro+vivo, GC, HGC27 - vitro+vivo, GC, MKN45
TumCP↓, TumCMig↓, TumCI↓, TumCG↓, *toxicity↓, Synergy↑, Ferroptosis↑, ACSL4↑, GPx4↓, ChemoSen↑, chemoP↑, AntiTum↑, Sepsis↓,
5026- QC,    Quercetin induces ferroptosis in gastric cancer cells by targeting SLC1A5 and regulating the p-Camk2/p-DRP1 and NRF2/GPX4 Axes
- in-vitro, GC, NA
SLC1A5↓, ROS↑, Iron↓, NRF2↓, GPx4↓, Ferroptosis↑,
1489- RES,    Molecular mechanisms of resveratrol as chemo and radiosensitizer in cancer
- Review, Var, NA
RadioS↑, ChemoSen↑, *BioAv↓, *BioAv↑, Ferroptosis↑, lipid-P↑, xCT/SLC7A11↓, GPx4↓, *BioAv↑, COX2/PTGS2↓, cycD1/CCND1↓, FasL↓, FOXP3↓, HLA↑, p‑NF-kB↓, BAX↑, Bcl-2↓, MALAT1↓,

Showing Research Papers: 101 to 150 of 186
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 186

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↑, 1,   antiOx↓, 2,   antiOx↑, 1,   Catalase↓, 1,   Fenton↑, 9,   GCLC↑, 1,   GCLM↑, 1,   GPx↓, 6,   GPx4↓, 74,   GPx4↑, 3,   GPx4↝, 1,   GPx4∅, 1,   GSH↓, 55,   GSH↑, 1,   GSH↝, 1,   i-GSH↓, 1,   GSH/GSSG↓, 6,   GSR↓, 1,   H2O2↑, 2,   HO-1↓, 5,   HO-1↑, 13,   HO-1↝, 1,   Iron↓, 2,   Iron↑, 49,   Iron↝, 3,   i-Iron↓, 1,   i-Iron↑, 9,   c-Iron↑, 1,   Keap1↓, 3,   Keap1↑, 2,   Keap1↝, 1,   lipid-P↓, 1,   lipid-P↑, 58,   MDA↓, 2,   MDA↑, 32,   i-MDA↑, 2,   NADH↓, 1,   NADPH/NADP+↓, 1,   NFE2L2↑, 1,   NOX4↑, 1,   NRF2↓, 23,   NRF2↑, 12,   NRF2↝, 1,   RNS↑, 1,   ROS↓, 2,   ROS↑, 113,   ROS↝, 1,   mt-ROS↑, 1,   selenoP↑, 1,   SOD↓, 4,   SOD1↑, 1,   TBARS↑, 1,   Trx↓, 1,   TrxR↓, 2,   TrxR1↓, 1,   xCT/SLC7A11↓, 22,   xCT/SLC7A11↑, 1,   xCT/SLC7A11∅, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 4,   Ferritin↑, 2,   FPN↝, 1,   FTH1↓, 6,   FTH1↑, 1,   FTL↑, 2,   IronCh↑, 2,   LIP↑, 1,   Mets↑, 1,   NCOA4↑, 4,   NCOA4↝, 1,   STEAP3↑, 1,   Tf↓, 1,   Tf↑, 3,   TfR1/CD71↓, 1,   TfR1/CD71↑, 1,   TfR1/CD71↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

BCR-ABL↓, 1,   CDC2↓, 1,   CDC25↝, 1,   compI↓, 1,   compIII↓, 1,   compV↓, 1,   ETC↓, 3,   MCU↓, 1,   Mortalin↓, 1,   mtDam↑, 9,   OXPHOS↓, 3,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↑, 1,   ACSL4↑, 7,   ACSL4↝, 1,   ACSL4∅, 1,   ACSL5↑, 2,   ALDOA↓, 1,   AMPK↑, 11,   p‑AMPK↑, 1,   ATP↓, 8,   ENO1↓, 1,   FAO↑, 1,   FASN↓, 1,   G6PD↓, 1,   GLS↓, 1,   GlucoseCon↓, 3,   Glycolysis↓, 7,   GSK‐3β↓, 2,   ac‑Histones↑, 1,   HK1↓, 1,   HK2↓, 4,   HMG-CoA↓, 1,   lactateProd↓, 4,   lactateProd↑, 1,   LDHA↓, 2,   MCT4↓, 1,   NADPH↓, 2,   PDK1 / PDPK1↓, 1,   PFKP↓, 1,   PKM2↓, 3,   PKM2↑, 1,   Pyruv↓, 1,   SAT1↑, 1,   SCD1↓, 2,   SIRT1↓, 1,   SIRT1↑, 2,   SLC1A5↓, 1,   SREBP2↓, 1,   TCA↓, 1,   Warburg↓, 2,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 2,   Apoptosis↑, 40,   BAX↑, 10,   Bax:Bcl2↑, 1,   Bcl-2↓, 9,   BIM↑, 2,   BNIP3↑, 1,   Casp↑, 8,   Casp3↑, 6,   cl‑Casp3↑, 7,   cl‑Casp3∅, 1,   Casp7↑, 2,   Casp8↑, 1,   Casp9↑, 3,   cl‑Casp9↑, 2,   Cupro↑, 1,   Cyt‑c↑, 7,   DR5↑, 2,   Fas↑, 1,   FasL↓, 1,   Ferroptosis↓, 5,   Ferroptosis↑, 147,   GranB/GZMB↝, 1,   iNOS↓, 1,   Mcl-1↓, 1,   MDM2↓, 2,   MOMP↑, 2,   necrosis↑, 2,   NOXA↑, 1,   oncosis↑, 1,   p38↑, 3,   Paraptosis↑, 1,   Perforin↝, 1,   Pyro↑, 4,   survivin↓, 4,   TumCD↓, 1,   TumCD↑, 5,   YAP/TEAD↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 20,   p‑Akt↓, 2,   Akt2↓, 1,   AMPKα↑, 1,   CaMKII ?, 1,   CaMKII ↓, 1,   cMET↓, 2,   EGFR↓, 2,   ERK↓, 5,   ERK↑, 2,   p‑ERK↓, 1,   IκB↑, 1,   JAK↓, 2,   JAK2↓, 1,   JNK↓, 1,   JNK↑, 3,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 5,   MAPK↑, 5,   p‑MAPK↓, 1,   p‑MAPK↑, 1,   mTOR↓, 15,   mTOR↑, 3,   p‑mTOR↓, 1,   OR13G1?, 1,   P70S6K↑, 1,   PI3K↓, 14,   p‑PI3K↓, 2,   PTEN↑, 3,   RET↓, 1,   Sp1/3/4↓, 1,   STAT3↓, 10,   STAT3↑, 1,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↑, 3,   ATFs↑, 1,   cMyc↓, 4,   DLEU1↓, 1,   DNMT1↓, 1,   DNMT1↑, 1,   DNMTs↓, 1,   FOXO1↓, 1,   FOXO3↑, 1,   HDAC↓, 2,   HDAC1↓, 1,   IGF2BP3/IMP3/KOC↓, 1,   JPT1/HN1↓, 1,   LINC01116↓, 1,   miR-107↑, 1,   miR-10b-5p↓, 1,   miR-139-5p↑, 1,   miR-155↓, 1,   miR-182-5p↓, 1,   miR-21↓, 2,   miR-224↓, 1,   miR-340↓, 1,   miR-34a↑, 2,   miR-384↑, 1,   miR-422a↑, 1,   miR-592↑, 1,   OCT4↓, 2,   other?, 1,   other↓, 2,   other↑, 3,   other↝, 4,   SOX2↓, 1,   SOX4↓, 2,   tumCV↓, 16,   tumCV↑, 1,   USF1↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 5,   eIF2α↓, 1,   eIF2α↑, 1,   ER Stress↑, 10,   Erlin1↑, 1,   GRP78/BiP↓, 1,   GRP78/BiP↑, 2,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 2,   HSP90↓, 4,   OTUB2↓, 1,   PERK↑, 2,   UPR↑, 3,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   ATG7↑, 1,   autolysosome↑, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 3,   p‑Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↑, 1,   LC3II↑, 3,   LC3s↑, 1,   lysoMP↑, 1,   p62↓, 3,   p62↑, 2,   p‑p62↑, 1,   TumAuto↑, 21,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   p‑ATM↑, 1,   p‑ATR↑, 1,   DNAdam↑, 8,   DNArepair↓, 1,   ERCC3↑, 1,   m-FAM72A↓, 1,   HR↓, 1,   p16↑, 2,   P53↓, 2,   P53↑, 13,   PARP↑, 2,   cl‑PARP↑, 3,   cl‑PARP∅, 1,   PCNA↓, 1,   RAD51↓, 1,   SIRT6↓, 1,   Telomerase↓, 1,   TOP2↑, 1,   TP53↑, 1,   XRCC1↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 4,   CDK1↑, 1,   CDK1↝, 1,   CDK2↓, 1,   CDK2↑, 1,   CDK4↓, 2,   CDK4↑, 1,   CDK4/6↓, 1,   CDK6↑, 1,   CDK7↓, 1,   CHK1↝, 1,   p‑CHK1↑, 2,   p‑Chk2↑, 1,   CycB/CCNB1↓, 3,   CycB/CCNB1↑, 1,   CycB/CCNB1↝, 1,   cycD1/CCND1↓, 5,   cycE/CCNE↑, 1,   cycE1↓, 1,   Ki-67↓, 6,   mitA↑, 1,   P21↑, 2,   p27/CDKN1B↑, 2,   TumCCA↑, 35,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Axin2↑, 1,   CD133↓, 1,   cMYB↓, 1,   CSCs?, 1,   CSCs↓, 6,   CSCs↑, 1,   CSCsMark↓, 1,   Diff↑, 1,   FOSL1↑, 1,   GDF15↓, 1,   Ki-67↓, 6,   mTORC1↓, 1,   Nanog↓, 3,   NOTCH↓, 3,   NOTCH1↓, 2,   Piezo1↑, 2,   TumCG↓, 33,   TumCP?, 1,   TumCP↓, 46,   TumCP↑, 4,   TumCP⇅, 1,   Wnt↓, 10,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

annexin II↓, 1,   AP-1↓, 2,   ASAP2↓, 1,   BACH1↑, 1,   Ca+2↓, 2,   Ca+2↑, 4,   E-cadherin↑, 4,   EMT↓, 14,   ITGB1↑, 1,   MALAT1↓, 1,   MMP16↓, 1,   MMP2↓, 5,   MMP3↓, 1,   MMP9↓, 6,   MMPs↓, 3,   MUC1-C↓, 1,   N-cadherin↓, 4,   NCAM↑, 1,   PCBP1↓, 1,   ROCK1↓, 1,   Sharpin↓, 1,   SMAD2↓, 1,   SMAD3↓, 1,   Snail↓, 1,   T-cadherin↑, 1,   TET1↑, 1,   TGF-β↓, 1,   TGF-β1↓, 1,   THBS1↓, 1,   TIMP2↓, 1,   TIMP2↑, 1,   TumCI↓, 21,   TumCI↑, 1,   TumCMig↓, 19,   TumCMig↑, 1,   TumMeta↓, 10,   TumMeta↑, 1,   TumPF↓, 2,   uPA↓, 3,   Vim↓, 5,   β-catenin/ZEB1↓, 8,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 12,   angioG↑, 1,   ECM/TCF↓, 1,   EGR1↓, 1,   Hif1a↓, 13,   Hif1a↑, 1,   NO↓, 2,   REL↑, 1,   VEGF↓, 10,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

CD36/FAT↑, 1,   EPR↑, 1,   GLUT1↓, 3,   GLUT4↓, 2,   MMP↓, 16,   MPT↑, 2,   OATPs↓, 1,   SLC12A5↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD44↓, 3,   CD8+↑, 1,   COX2/PTGS2↓, 5,   CXCR4↓, 1,   DR4↑, 1,   Eos↑, 1,   FOXP3↓, 1,   HLA↑, 1,   HMGB1↓, 3,   IL1↓, 2,   IL12↑, 1,   IL1β↓, 2,   IL2↓, 1,   IL2↑, 1,   IL6↓, 1,   IL8↓, 1,   Imm↑, 7,   Imm↝, 1,   Inflam↓, 3,   LRIG1↑, 1,   pol-M1↑, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 1,   MCT1↓, 1,   MIP2↓, 1,   Neut↑, 1,   NF-kB↓, 15,   NF-kB↑, 1,   p‑NF-kB↓, 1,   NK cell↑, 1,   NLRP3↑, 1,   PD-L1↓, 4,   PGE2↓, 1,   TCF7/TCF1↓, 1,   TLR1↑, 1,   TNF-α↓, 2,   TNF-α↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

PTN↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AR↓, 1,   AR↝, 1,   CYP24A1↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 8,   BioAv↑, 4,   BioAv↝, 4,   BioEnh↑, 1,   ChemoSen↑, 46,   CompStab↓, 1,   CYP3A4↓, 1,   DDS↑, 1,   Dose?, 1,   Dose↑, 2,   Dose⇅, 1,   Dose↝, 12,   Dose∅, 1,   eff↓, 17,   eff↑, 24,   eff↝, 2,   Half-Life↓, 4,   MDR1↓, 3,   P-gp/ABCB1↓, 1,   RadioS↑, 7,   RadioS↝, 1,   selectivity↑, 13,   Synergy↑, 19,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   AR↝, 1,   BMD↑, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 2,   Ferritin↓, 4,   Ferritin↑, 2,   IL6↓, 1,   LDH↓, 1,   PD-L1↓, 4,   RBM3↑, 1,   TP53↑, 1,   Tumccf↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↓, 1,   AntiCan↑, 10,   antiCG↓, 1,   antiNeop↑, 1,   AntiTum↓, 1,   AntiTum↑, 5,   chemoP↑, 4,   hepatoP↑, 1,   OS↑, 3,   QoL↑, 1,   radioP↑, 2,   Risk↓, 2,   toxicity↓, 3,   toxicity↑, 2,   toxicity↝, 1,   TumVol↓, 7,   TumW↓, 4,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   GutMicro↑, 1,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 2,  
Total Targets: 495

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 2,   antiOx↓, 1,   antiOx↑, 14,   Catalase↑, 5,   Fenton↓, 1,   GPx↑, 4,   GPx4↓, 2,   GPx4↑, 15,   GPx4∅, 1,   GSH↓, 2,   GSH↑, 10,   GSR↓, 1,   GSTs↓, 1,   GSTs↑, 1,   HO-1?, 1,   HO-1↓, 2,   HO-1↑, 9,   HO-1↝, 1,   HO-1∅, 1,   Iron↓, 4,   Iron↝, 1,   i-Iron↓, 3,   lipid-P↓, 8,   lipid-P↑, 3,   MDA↓, 9,   MDA↑, 1,   MPO↓, 1,   NQO1↑, 1,   NRF2↓, 2,   NRF2↑, 21,   NRF2∅, 1,   ROS↓, 22,   ROS↑, 2,   ROS∅, 1,   i-ROS↑, 1,   mt-ROS↓, 1,   SOD↓, 1,   SOD↑, 12,   TAC↑, 3,   TBARS↓, 1,   xCT/SLC7A11↓, 1,   xCT/SLC7A11↑, 5,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   FTH1↓, 1,   FTH1↑, 1,   IronCh↑, 3,   NCOA4↝, 1,   TfR1/CD71↓, 2,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

DRP1/DNM1L↓, 1,   MFN2↑, 1,   mtDam↓, 4,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   5LO↓, 1,   ACSL4↓, 5,   ACSL4∅, 1,   ALAT↓, 1,   AMPK↑, 2,   p‑AMPK↑, 1,   ATP↑, 2,   FAO↓, 1,   GlucoseCon↑, 1,   GSK‐3β↑, 1,   NADPH↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 8,   Apoptosis↑, 1,   BAX↓, 4,   BAX↑, 1,   Bcl-2↓, 2,   Bcl-2↑, 2,   Casp3↓, 4,   Casp3↑, 1,   Cyt‑c↓, 1,   Fas↓, 1,   Ferroptosis↓, 32,   Ferroptosis↑, 4,   iNOS↓, 2,   p38↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 2,   ERK↓, 1,   JNK↓, 4,   MAPK↓, 4,   mTOR↓, 1,   PI3K↓, 1,   PKCδ↑, 1,   PTEN↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF2↑, 1,   ATF4↓, 1,   DNMT1↓, 1,   DNMTs↓, 1,   FOXO3↑, 1,   KLF4↑, 1,   other↓, 2,   other↑, 2,   other↝, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 2,   GRP78/BiP↓, 3,   IRE1↓, 2,   PERK↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3B↑, 1,   MitoP↑, 1,   p62↓, 2,   p62↑, 1,   PARK2↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

HH↓, 1,   neuroG↑, 1,   TumCG↓, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   Cartilage↑, 1,   MMP9↓, 1,   NFAT↓, 1,   ROCK1↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

CD31/PECAM-1↑, 1,   NO↓, 2,   TXA2↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 5,   BBB↝, 1,   BBB∅, 2,   CellMemb↑, 1,   CLDN4↑, 1,   GLUT4↑, 1,   H+/K+-ATPase↓, 1,   MMP↑, 3,   OCLN↑, 1,   TJ↑, 2,   TRPM7↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 4,   HMGB1↓, 1,   IL17↓, 1,   IL1β↓, 5,   IL6↓, 5,   Inflam↓, 19,   NeuroI↓, 1,   NF-kB↓, 3,   NF-kB↑, 1,   NK cell↑, 1,   NLRP3↓, 2,   PGE2↓, 1,   RAGE↓, 1,   TLR4↓, 2,   TNF-α↓, 6,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 3,   BDNF↑, 2,   PSD95↑, 1,   SNAP25↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 1,   Aβ↓, 4,   Aβ42↓, 1,   BACE/β-secretase↓, 1,   tau↓, 1,   p‑tau↓, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   AKR1C3/17β-HSD5/PGF Synthase↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

AKR1B1/ALR2↑, 1,   AKR1B10↝, 1,   BioAv↓, 8,   BioAv↑, 8,   BioAv↝, 4,   ChemoSen↑, 1,   Dose?, 3,   eff↓, 1,   eff↑, 5,   selectivity↑, 1,   Synergy↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   anemia↓, 1,   AST↓, 1,   BloodF↑, 1,   BP↓, 1,   BUN↓, 2,   creat↓, 2,   CRP↓, 1,   Ferritin↓, 1,   Ferritin↑, 1,   HemoG↑, 1,   IL6↓, 5,   IRes↝, 1,   LDH↑, 1,   RAGE↓, 1,   RBC↑, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 1,   AntiDiabetic↑, 1,   AntiTum↑, 1,   cardioP↑, 7,   chemoP↑, 3,   cognitive↑, 5,   hepatoP↓, 1,   hepatoP↑, 3,   Learn↑, 2,   memory↑, 4,   motorD↑, 1,   neuroP↑, 10,   Obesity↓, 2,   radioP↑, 1,   RenoP↑, 6,   RenoP↝, 1,   Risk↓, 1,   Strength↑, 1,   Stroke↓, 4,   toxicity↓, 10,   toxicity↑, 1,   toxicity↝, 2,   toxicity∅, 1,   Weight∅, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   Bacteria↓, 1,   GutMicro↑, 3,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 222

Scientific Paper Hit Count for: Ferroptosis, Ferroptosis
19 Artemisinin
8 Matrine
8 Shikonin
8 Selenite (Sodium)
7 Luteolin
7 Cisplatin
7 erastin
7 Curcumin
4 Ashwagandha(Withaferin A)
4 Baicalein
4 Copper and Cu NanoParticles
4 Sulfasalazine
4 Honokiol
4 Kaempferol
3 doxorubicin
3 Boron
3 immunotherapy
3 Docosahexaenoic Acid
3 Isoliquiritigenin
3 Phenethyl isothiocyanate
3 Sulforaphane (mainly Broccoli)
3 Licochalcone A
3 Piperlongumine
3 Rosmarinic acid
3 salinomycin
2 Andrographis
2 Berberine
2 Betulinic acid
2 brusatol
2 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
2 Chlorogenic acid
2 Citric Acid
2 Coenzyme Q10
2 Disulfiram
2 Formononetin
2 Gambogic Acid
2 Ginkgo biloba
2 Ginkgetin
2 Hyperoside
2 isoquercitrin
2 Juglone
2 Lactoferrin/Talactoferrin
2 Magnetic Fields
2 Magnetic Field Rotating
2 Vitamin C (Ascorbic Acid)
2 Morin
1 3-bromopyruvate
1 cetuximab
1 Astragalus
1 Silver-NanoParticles
1 Allicin (mainly Garlic)
1 5-fluorouracil
1 Docetaxel
1 Astaxanthin
1 Radiotherapy/Radiation
1 Atorvastatin
1 Ras-selective lethal 3
1 Boswellia (frankincense)
1 Carvacrol
1 Celastrol
1 Vitamin K2
1 Crocetin
1 Cucurbitacin
1 diet Methionine-Restricted Diet
1 Diindolylmethane
1 Dipyridamole
1 EGCG (Epigallocatechin Gallate)
1 Fenbendazole
1 ferumoxytol
1 Gallic acid
1 Hydrogen Gas
1 HydroxyTyrosol
1 Isorhamnetin
1 isoorientin
1 Isothiocyanates
1 Allyl isothiocyanate
1 Benzyl isothiocyanate
1 Lactobacillus
1 MCT oil
1 magnetic nanoparticles
1 Zeolite
1 Myricetin
1 nicotinamide adenine dinucleotide
1 Orlistat
1 Patchouli Oil (Pogostemon cablin)
1 Phenylbutyrate
1 Psoralidin
1 Quercetin
1 Resveratrol
1 Selenium
1 Silymarin (Milk Thistle) silibinin
1 Salvia miltiorrhiza
1 Spermidine
1 Osimertinib
1 Adagrasib
1 Aflavin-3,3′-digallate
1 Urolithin
1 Vitexin
1 Isovitexin
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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