cardioP Cancer Research Results

cardioP, cardioProtective: Click to Expand ⟱
Source:
Type:
CardioProtective


Scientific Papers found: Click to Expand⟱
4769- CoQ10,    CoQ10 Is Key for Cellular Energy and Cancer Support
- Review, Var, NA
Risk↓, TumCG↓, angioG↓, TumCD↑, *toxicity↓, *BioAv↑, MMPs↓, Inflam↓, chemoP↑, cardioP↑, *ROS↓, *toxicity↝, Dose?,
5780- CRMs,  HCAs,  RES,  Sper,  ASA  Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential
- Review, Var, NA
*OS↑, *AntiAge↑, *cardioP↑, *neuroP↑, AntiCan↑, *TNF-α↓, *Weight↓, *BP↓, *Inflam↓, *Insulin↓, *ROS↓, *AMPK↑, *mTOR↓, *SIRT1↑, CRM↑,
6181- Cro,    Crocetin: A Systematic Review
- Review, Var, NA - Review, AD, NA
cardioP↑, hepatoP↑, *neuroP↑, AntiCan↑, *AntiDiabetic↑, *memory↑, *BioAv↓, *ROS↓, Apoptosis↑, *lipid-P↓, *SOD↑, SOD↓, ERα/ESR1↓, HDAC2↓, TumCCA↑, Bax:Bcl2↑, IL6↓, IL8↓, Shh↓, COX2↑, *GSK‐3β↓, *ERK↓, *tau↓, *ROS↓, *GSTs↑, *Catalase↑, *SOD↑, *BioAv↑,
6315- Cro,    Functional Mechanisms of Dietary Crocin Protection in Cardiovascular Models under Oxidative Stress
- in-vivo, NA, NA
*cardioP↑, *Inflam↓, *antiOx↑, *ROS↓, *AntiCan↑, *memory↑, *NF-kB↓, *TLR1↓, *NRF2↑, *HO-1↑, *lipid-P↓, *DNAdam↓, PTEN↓, MMP↓,
6300- Cro,    Interaction of saffron and its constituents with Nrf2 signaling pathway: A review
- Review, Nor, NA - Review, Arthritis, NA
*antiOx↑, *Inflam↓, *AntiTum↑, *hepatoP↑, *cardioP↑, *neuroP↑, *NRF2↑, *NF-kB↓, *iNOS↓, *COX2↓, *IL6↓, *IL10↓, *IL1β↓, *TNF-α↓, *HO-1↑, ROS↑, NQO1↑, NRF2↑, HO-1↑, NQO2↑, LDHA↓, ATP↓, *hepatoP↑, *SOD↑, *Catalase↑, *GPx↑, *NRF2↑, *ROS↓, *cardioP↑, *ER Stress↓, *GRP78/BiP↓, *CHOP↓, *Apoptosis↓, *miR-34a↓, *SIRT1↑, chemoP↑,
6532- CRV,  doxoR,    R-(-)-carvone Attenuated Doxorubicin Induced Cardiotoxicity In Vivo and Potentiated Its Anticancer Toxicity In Vitro
- in-vivo, BC, MCF7 - in-vivo, Nor, H9c2
tumCV↓, ChemoSen↑, cardioP↑, *Catalase↑,
6201- Cuc,    Cucurbitacin B and Its Derivatives: A Review of Progress in Biological Activities
- Review, Var, NA - Review, AD, NA
*toxicity↑, *antiOx↑, *Inflam↓, *NLRP3↓, *NF-kB↓, *neuroP↑, *memory↑, *GABA↑, *cardioP↑, AntiTum↑, p‑FAK↓, ROS↑, TumMeta↑, TumCP↓, Apoptosis↑, P53↑, P21↑, TumCCA↑, p27↑, CDK4↓, CDK2↓, cycD1/CCND1↓, cycE/CCNE↓, STAT3↓, ChemoSen↑, MMP2↓, MMP9↓, VEGF↓, TumCMig↓, angioG↓, NOTCH↓, EMT↓, toxicity↑, BioAv↑, EPR↑,
6207- CUR,    Enhancing the Bioavailability and Bioactivity of Curcumin for Disease Prevention and Treatment
- Review, Var, NA - Review, AD, NA
*AntiCan↑, *Obesity↓, *Inflam↓, *lipid-P↓, *BioAv↓, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *mt-SOD↑, *MDA↓, *BBB↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroG↑, *memory↑, cardioP↑,
6214- CUR,    Curcumin Nanoparticles-related Non-invasive Tumor Therapy, and Cardiotoxicity Relieve
TumCD↓, TumCI↓, *Inflam↓, *antiOx↓, *AntiTum↓, NF-kB↓, COX2↓, Casp9↓, ROS↑, BioAv↑, RadioS↑, ChemoSen↑, Imm↑, PhotoS↑, sonoS↑, 5LO↓, iNOS↓, IL2↓, TNF-α↓, Casp9↑, Casp3↑, Bcl-2↓, BAX↑, Apoptosis↑, ER Stress↑, cycD1/CCND1↓, CDK2↓, CycB/CCNB1↓, TumCCA↑, MMPs↓, *radioP↑, chemoP↑, hepatoP↑, cardioP↑, eff↑, PhotoS↑, eff↑, ROS↑, GSH↓,
6215- CUR,    Curcumin: biochemistry, pharmacology, advanced drug delivery systems, and its epigenetic role in combating cancer
- Review, Var, NA
*antiOx↑, *Inflam↓, *BioAv↓, NF-kB↓, PI3K↓, Akt↓, Wnt↓, β-catenin/ZEB1↓, DNMTs↓, TumCI↓, TumMeta↓, *BioAv↑, *BioAv↑, angioG↓, VEGF↓, MMPs↓, *ROS↓, *SOD↑, *Catalase↑, *GSTs↑, *HO-1↑, *NRF2↑, mTOR↓, GSK‐3β↓, FOXO1↓, *radioP↑, *IL1↓, *IL6↓, *TNF-α↓, HATs↓, HDAC↓, ROS↑, ROS↑, MMP↓, Casp↑, Cyt‑c↑, COX1↓, COX2↓, PGE2↓, *cytoP450↓, ChemoSen↑, cardioP↑, eff↑,
6421- CUR,    Curcumin simultaneously improves mitochondrial dynamics and myocardial cell bioenergy after sepsis via the SIRT1-DRP1/PGC-1α pathway
- in-vivo, Nor, NA
*SIRT1↓, *PGC-1α↑, *NRF2↑, *DRP1/DNM1L↓, *Sepsis↓, *OS↑, *cardioP↑,
2818- CUR,    Novel Insight to Neuroprotective Potential of Curcumin: A Mechanistic Review of Possible Involvement of Mitochondrial Biogenesis and PI3/Akt/ GSK3 or PI3/Akt/CREB/BDNF Signaling Pathways
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *Apoptosis↓, *cognitive↑, *cardioP↑, other↑, *COX2↓, *IL1β↓, *TNF-α↓, NF-kB↓, *PGE2↓, *iNOS↓, *NO↓, *IL2↓, *IL4↓, *IL6↓, *INF-γ↓, *GSK‐3β↓, *STAT↓, *GSH↑, *MDA↓, *lipid-P↓, *SOD↑, *GPx↑, *Catalase↑, *GSR↓, *LDH↓, *H2O2↓, *Casp3↓, *Casp9↓, *NRF2↑, *AIF↓, *ATP↑,
6702- DFC,    Diclofenac
- Review, Nor, NA
*Inflam↓, *COX1↓, *COX2↓, *PGE2↓, *TXA2↓, *BioAv↑, *Dose↝, *cardioP↓,
6698- DFC,    Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts
- in-vivo, Nor, NA
*cardioP↓, *ROS↑, MMP↓, compIII↓,
6687- DFC,    Diclofenac-containing medicines - referral
- Review, Nor, NA
*Pain↓, *Inflam↓, *AntiArt↑, *cardioP↓,
6663- DFE,    Nutraceuticals of Phoenix dactylifera L.: Physicochemistry, Nutritional Value and Therapeutic Potential
- Review, Nor, NA - Review, AD, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *AntiDiabetic↑, *AntiCan↑, *AntiArt↑, *neuroP↑, *hepatoP↑, *GastroP↑, *other↝, *cardioP↑, *cognitive↑, *ROS↓, *memory↑, *other↝, *SOD↑, *Catalase↑, *GSH↑, *GA↑, *Catechins↑, *FA↑, *QC↑, Api↑, *CA↑, *Imm↑, *Phen↑, *IL1β↓, *TGF-β↓, *COX1↓, *COX2↓, TumCP↓, Casp3↑, TumMeta↓, *GutMicro↑,
6719- DHCA,    Anticancer potential of dihydrocaffeic acid: a chlorogenic acid metabolite
- in-vitro, BC, MCF7 - in-vitro, Pca, PC3 - in-vitro, Liver, HepG2 - in-vitro, CRC, HCT116 - in-vitro, Nor, HDFa
*antiOx↑, *cardioP↑, *neuroP↑, selectivity↑, selectivity↓, TumCCA↑, ROS↑, mtDam↑,
6710- dietF,    The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on fermented foods
- Review, Nor, NA
*other↝, *toxicity↓, *toxicity↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *Imm↑,
6717- dietF,    Fermented foods consumption, all-cause, and cause-specific mortality: a meta-analysis of prospective cohort studies
- Review, CardioV, NA
*Risk↓, *cardioP↑, *GutMicro↑, *OS↑, *BP↓,
6711- dietF,    Gut-microbiota-targeted diets modulate human immune status
- Trial, Nor, NA
*GutMicro↑, *Inflam↓, *Imm↑, *Obesity↓, *AntiDiabetic↑, *AntiCan↑, *cardioP↑, *IL6↓, *IL10↓, *IL12↓,
6716- dietF,    Current Research in Fermented Foods: Bridging Tradition and Science
- Review, Nor, NA
*GutMicro↑, *Inflam↓, *BP↓, *LDL↓, *HDL↑, *CRP↓, *IL6↓, *TNF-α↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *neuroP↑, *cognitive↑,
5071- dietSTF,    Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review
- Review, Var, NA - Review, AD, NA
Risk↓, TumCMig↓, IGF-1↓, TumAuto↑, Inflam↓, ChemoSen↑, Apoptosis↑, chemoP↑, *glucose↓, *AntiDiabetic↑, *cardioP↑, *LDL↓, *BP↓, *neuroP↑, *cognitive↑, *memory↑, *OS↑, *QoL↑, Imm↑, TumCG↓, ChemoSideEff↓, QoL↑,
4987- Dipy,  ATV,    Enhanced cardioprotection against ischemia-reperfusion injury with a dipyridamole and low-dose atorvastatin combination
- in-vivo, Nor, NA
*cardioP↑, *Akt↑, *eNOS↑,
6357- DRE,    New Perspectives on the Effect of Dandelion, Its Food Products and Other Preparations on the Cardiovascular System and Its Diseases
- Review, Nor, NA
*cardioP↑, *Dose↝, *Dose↝, *toxicity∅, *toxicity↓, *BP↓, *Inflam↓, *Bacteria↓, *Imm↑, *lipid-P↓, *AST↓, *ALAT↓, *AntiAg↑, *ROS↓, *AntiThr↑,
6801- EA,    A radiotherapeutic paradox: ellagic acid sensitizes tumors while attenuating radiation-induced myocardial injury
- vitro+vivo, BC, 4T1
TumCCA↑, CDK4↓, RadioS↑, TumCG↓, *radioP↑, *cardioP↑, *antiOx↑, *ROS↓, Dose↑, selectivity↑, BioAv↓,
1607- EA,    Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions
- Review, GC, NA
STAT3↓, TumCP↓, Apoptosis↑, NF-kB↓, EMT↓, RadioS↑, antiOx↑, COX1↓, COX2↓, cMyc↓, Snail↓, Twist↓, MMP2↓, P90RSK↓, CDK8↓, PI3K↓, Akt↓, TumCCA↑, Casp8↑, PCNA↓, TGF-β↓, Shh↓, NOTCH↓, IL6↓, ALAT↓, ALP↓, AST↓, VEGF↓, P21↑, *toxicity∅, *Inflam↓, *cardioP↑, *neuroP↑, *hepatoP↑, ROS↑, *NRF2↓, *GSH↑,
6777- EGCG,    Health Benefits and Chemical Composition of Matcha Green Tea: A Review
- Review, Nor, NA
*antiOx↑, *Inflam↓, AntiCan↑, Risk↓, TumCG↓, Apoptosis↑, *ROS↓, *cardioP↑, *Imm↑, *AntiViral↑, *cognitive↑,
6784- EGCG,    Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *cardioP↑, *neuroP↑, *GutMicro↑, *AntiBio↑, *ROS↓, *TNF-α↓, *IL6↓, TumCP↓, *LDL↓, *NO↓, *Obesity↓, *p‑tau↓, *Aβ↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *NLRP3↓, *mTOR↓, TumCCA↑, NRF2↓, Apoptosis↑, SIRT1↓, miR-25-5p↓, PARP↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, EMT↓, TumCI↓, TumCMig↓, TGF-β↓, Smad1↓, STAT3↓, VEGF↓, angioG↓, Imm↑, EGFR↓, *GutMicro↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *BioAv↑, *eff↑, *BioAv↑, eff↑, ChemoSen↑, *toxicity↝,
3231- EGCG,    Epigallocatechin-3-gallate restores mitochondrial homeostasis impairment by inhibiting HDAC1-mediated NRF1 histone deacetylation in cardiac hypertrophy
- in-vitro, Nor, NA
*HDAC↓, *cardioP↑, *Nrf1↑, *PGC-1α↓,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
3205- EGCG,    The Role of Epigallocatechin-3-Gallate in Autophagy and Endoplasmic Reticulum Stress (ERS)-Induced Apoptosis of Human Diseas
- Review, Var, NA - Review, AD, NA
Beclin-1↑, ROS↑, Apoptosis↑, ER Stress↑, *Inflam↓, *cardioP↑, *antiOx↑, *LDL↓, *NF-kB↓, *MPO↓, *glucose↓, *ROS↓, ATG5↑, LC3B↑, MMP↑, lactateProd↓, VEGF↓, Zeb1↑, Wnt↑, IGF-1R↑, Fas↑, Bak↑, BAD↑, TP53↓, Myc↓, Casp8↓, LC3II↑, NOTCH3↓, eff↑, p‑Akt↓, PARP↑, *Cyt‑c↓, *BAX↓, *memory↑, *neuroP↑, *Ca+2?, GRP78/BiP↑, CHOP↑, ATF4↑, Casp3↑, Casp8↑, UPR↑,
3211- EGCG,    Antioxidation Function of EGCG by Activating Nrf2/HO-1 Pathway in Mice with Coronary Heart Disease
- in-vivo, NA, NA
*cardioP↑, *VEGF↓, *MMP2↓, *SOD↑, *ROS↓, *HO-1↑, *NQO1↑, *NRF2↑,
2302- EGCG,    Flavonoids Targeting HIF-1: Implications on Cancer Metabolism
- Review, Var, NA
TumCP↓, Hif1a↓, LDHA↓, PFK↓, cardioP↑, Glycolysis↓, PKM2↓,
2563- EGCG,    Cardioprotective effect of epigallocatechin gallate in myocardial ischemia/reperfusion injury and myocardial infarction: a meta-analysis in preclinical animal studies
- Review, NA, NA
cardioP↑, ROS↑, AntiAg↑, eff↑, COX1↓,
5227- EMD,    Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy
- vitro+vivo, Nor, NA
*cardioP↑, HDAC↓, HDAC1↓, HDAC2↓, ac‑H3↑, Dose↝, BioAv↓,
6388- Eug,    Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review
- Review, Var, NA
Dose↝, AntiCan↑, *Inflam↓, *cardioP↑, *neuroP↑, angioG↓, TumMeta↓, *BioAv↑, *eff↑, *toxicity↝, antiNeop↑, TumCCA↑, Apoptosis↑, *antiOx↑, *lipid-P↓, *ROS↓, *SOD↑, *Catalase↑, *GSTs↑, *GPx↑, *iNOS↓, *COX2↓, *IL6↓, *TNF-α↓, *AntiArt↑, *Bacteria↓, TumAuto↑, PI3K↓, Akt↓, FOXO3↝, BAX↑, mTOR↓, NF-kB↓, P53↑, TumCG↓, CSCs↓, CD44↓, EpCAM↓, NOTCH1↓, OCT4↓, Bcl-2↓, PDK1↓, HER2/EBBR2↓, BAD↓, cycD1/CCND1↓, ROS↑, Casp3↑, selectivity↑, MMP2↓, MMP9↓, TIMP1↑, VEGF↓, VEGFR1↓, RECK↑, TIMP2↑, DNAdam↑, MMP↓, Thiols↓, PARP↑, *Pain↓, E2Fs↓, survivin↓,
6323- Eug,    Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
- Review, Var, NA - Review, Arthritis, NA
*AntiCan↑, *AntiDiabetic↑, *cardioP↑, *toxicity↝, *GutMicro↑, *neuroP↑, *BioAv⇅, *BioAv↝, *antiOx↑, *Inflam↑, *AntiArt↑, *TNF-α↓, *IL6↓, *IL10↓, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TAC↑, TumCMig↓, TumCI↓, Akt↑, FOXO3↑, Casp3↑, Casp9↑, P21↑, angioG↓, TumCI↓, Apoptosis↑, NF-kB↓, eff↑, eff↑, ChemoSen↑, NA↑, Casp3↑, Casp9↑, *AntiDiabetic↑, *glucose↓, *ROS↓, *Inflam↓, *MDA↓, *GSH↑, *BioAv↑,
3710- FA,    Therapeutic Potential of Ferulic Acid in Alzheimer's Disease
- Review, AD, NA
*antiOx↑, *AntiCan↑, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *Aβ↓, *ROS↓, *AChE↓,
3712- FA,    Ferulic Acid: A Hope for Alzheimer’s Disease Therapy from Plants
- Review, AD, NA
*antiOx↑, *Inflam↓, *ROS↓, *Aβ↓, *HO-1↑, *HSP70/HSPA5↑, *ERK↑, *Akt↑, *iNOS↓, *COX2↓, *cardioP↑, *memory↑, *IL2↓, *cognitive↑, *APP↓, *SOD↑, *Catalase↑, *Akt↑, *BioAv↑,
2846- FIS,    Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity
- in-vitro, Nor, NA
*cardioP↑, *ROS↓, *Casp↓, *DNAdam↓,
2828- FIS,    Fisetin, a Potent Anticancer Flavonol Exhibiting Cytotoxic Activity against Neoplastic Malignant Cells and Cancerous Conditions: A Scoping, Comprehensive Review
- Review, Var, NA
*neuroP↑, *antiOx↑, *Inflam↓, RenoP↑, COX2↓, Wnt↓, EGFR↓, NF-kB↓, Casp3↑, Ca+2↑, Casp8↑, TumCCA↑, CDK1↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, *P53↓, *P21↓, *p16↓, mTORC1↓, mTORC2↓, P53↑, P21↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, CDK4↓, BAX↑, Bcl-2↓, PCNA↓, HER2/EBBR2↓, Cyt‑c↑, MMP↓, cl‑Casp9↑, MMP2↓, MMP9↓, cl‑PARP↑, uPA↓, DR4↑, DR5↑, ROS↓, AIF↑, CDC25↓, Dose↑, CHOP↑, ROS↑, cMyc↓, cardioP↑,
2525- H2,    Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis
- in-vivo, NA, NA
OS↓, cardioP↑, *AST↓, ALAT↓, *ROS↓, *MDA↓, *hepatoP↑, *Inflam↓, chemoP↑,
2516- H2,    Hydrogen Gas in Cancer Treatment
- Review, Var, NA
*Half-Life↓, *ROS↓, *selectivity↑, *SOD↑, *HO-1↑, *NRF2↑, *chemoP↑, *radioP↑, ROS↑, *Inflam↓, eff↑, *TNF-α↓, *IL6↓, *cl‑Casp8↑, *Bax:Bcl2↓, *Apoptosis↓, *cardioP↑, *hepatoP↑, *RenoP↑, *chemoP↑, eff↝, chemoP↑, radioP↑, eff↑, TumCG↓, Ki-67↓, VEGF↓, selectivity↑,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
2868- HNK,    Honokiol: A review of its pharmacological potential and therapeutic insights
- Review, Var, NA - Review, Sepsis, NA
*P-gp↓, *ROS↓, *TNF-α↓, *IL10↓, *IL6↓, eIF2α↑, CHOP↑, GRP78/BiP↑, BAX↑, cl‑Casp9↑, p‑PERK↑, ER Stress↑, Apoptosis↑, MMPs↓, cFLIP↓, CXCR4↓, Twist↓, HDAC↓, BMPs↑, p‑STAT3↓, mTOR↓, EGFR↓, NF-kB↓, Shh↓, VEGF↓, tumCV↓, TumCMig↓, TumCI↓, ERK↓, Akt↓, Bcl-2↓, Nestin↓, CD133↓, p‑cMET↑, RAS↑, chemoP↑, *NRF2↑, *NADPH↓, *p‑Rac1↓, *ROS↓, *IKKα↑, *NF-kB↓, *COX2↓, *PGE2↓, *Casp3↓, *hepatoP↑, *antiOx↑, *GSH↑, *Catalase↑, *RenoP↑, *ALP↓, *AST↓, *ALAT↓, *neuroP↑, *cardioP↑, *HO-1↑, *Inflam↓,
2901- HNK,  doxoR,    Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts
- in-vivo, Nor, NA
*mitResp↑, *PPARγ↑, *Inflam↓, *ROS↓, *cardioP↑, *SOD2↑, *LDH↓,
2889- HNK,  doxoR,    Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice
- in-vivo, Nor, NA
*SIRT3↑, chemoP↑, *cardioP↑, mtDam↑, ROS↑, *ROS↓, *MMP↑,
2893- HNK,  doxoR,    Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts
- in-vivo, Nor, NA
*mitResp↑, *PPARγ↑, *cardioP↑, *SIRT3↑, *ROS↓, *GSH↑, *SOD2↑,
2894- HNK,    Pharmacological features, health benefits and clinical implications of honokiol
- Review, Var, NA - Review, AD, NA
*BioAv↓, *neuroP↑, *BBB↑, *ROS↓, *Keap1↑, *NRF2↑, *Casp3↓, *SIRT3↑, *Rho↓, *ERK↓, *NF-kB↓, angioG↓, RAS↓, PI3K↓, Akt↓, mTOR↓, *memory↑, *Aβ↓, *PPARγ↑, *PGC-1α↑, NF-kB↓, Hif1a↓, VEGF↓, HO-1↓, FOXM1↓, p27↑, P21↑, CDK2↓, CDK4↓, CDK6↓, cycD1/CCND1↓, Twist↓, MMP2↓, Rho↑, ROCK1↑, TumCMig↓, cFLIP↓, BMPs↑, OCR↑, ECAR↓, *AntiAg↑, *cardioP↑, *antiOx↑, *ROS↓, P-gp↓,
2926- LT,    Luteolin ameliorates rat myocardial ischemia-reperfusion injury through peroxiredoxin II activation: LUT's cardioprotection through PRX II
- in-vitro, Nor, H9c2
*cardioP↑, *PrxII↑,

Showing Research Papers: 101 to 150 of 240
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 240

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   GSH↓, 1,   HO-1↓, 1,   HO-1↑, 1,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↓, 1,   ROS↑, 14,   SOD↓, 1,   Thiols↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   ATP↓, 1,   CDC25↓, 1,   compIII↓, 1,   MMP↓, 5,   MMP↑, 1,   mtDam↑, 2,   OCR↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   cMyc↓, 2,   CRM↑, 1,   ECAR↓, 1,   GlutMet↓, 1,   Glycolysis↓, 1,   lactateProd↓, 1,   LDHA↓, 2,   PDK1↓, 1,   PFK↓, 1,   PKM2↓, 1,   SIRT1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 6,   Akt↑, 1,   p‑Akt↓, 1,   Apoptosis↑, 11,   BAD↓, 1,   BAD↑, 1,   Bak↑, 2,   BAX↑, 5,   Bax:Bcl2↑, 1,   Bcl-2↓, 5,   Bcl-xL↓, 1,   Casp↑, 1,   Casp3↑, 9,   Casp8↓, 1,   Casp8↑, 3,   Casp9↓, 1,   Casp9↑, 4,   cl‑Casp9↑, 2,   cFLIP↓, 2,   Cyt‑c↑, 3,   DR4↑, 1,   DR5↑, 1,   Fas↑, 1,   HGF/c-Met↓, 1,   iNOS↓, 1,   MAPK↓, 2,   Myc↓, 1,   p27↑, 2,   survivin↓, 1,   Telomerase↓, 1,   TumCD↓, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 2,   miR-25-5p↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ac‑H3↑, 1,   HATs↓, 1,   other↑, 1,   PhotoS↑, 2,   sonoS↑, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP↑, 3,   eIF2α↑, 1,   ER Stress↑, 4,   GRP78/BiP↑, 2,   NQO2↑, 1,   p‑PERK↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1↑, 1,   LC3B↑, 1,   LC3II↑, 1,   TumAuto↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   DNMTs↓, 2,   P53↑, 4,   PARP↑, 4,   cl‑PARP↑, 1,   PCNA↓, 2,   TP53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 4,   CDK4↓, 4,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 5,   cycE/CCNE↓, 1,   E2Fs↓, 1,   P21↑, 5,   TumCCA↑, 9,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   CD44↓, 1,   CDK8↓, 1,   p‑cMET↑, 1,   CSCs↓, 1,   EMT↓, 3,   EpCAM↓, 1,   ERK↓, 1,   FOXM1↓, 1,   FOXO1↓, 1,   FOXO3↑, 1,   FOXO3↝, 1,   GSK‐3β↓, 1,   HDAC↓, 4,   HDAC1↓, 1,   HDAC2↓, 2,   IGF-1↓, 1,   IGF-1R↑, 1,   mTOR↓, 5,   mTORC1↓, 1,   mTORC2↓, 1,   Nestin↓, 1,   NOTCH↓, 2,   NOTCH1↓, 1,   NOTCH3↓, 1,   OCT4↓, 1,   P90RSK↓, 1,   PI3K↓, 5,   PTEN↓, 1,   PTEN↑, 1,   RAS↓, 1,   RAS↑, 1,   Shh↓, 3,   STAT3↓, 3,   p‑STAT3↓, 1,   TumCG↓, 7,   Wnt↓, 2,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↑, 1,   Ca+2↑, 1,   p‑FAK↓, 1,   Ki-67↓, 1,   MMP2↓, 5,   MMP9↓, 4,   MMPs↓, 5,   RECK↑, 1,   Rho↑, 1,   ROCK1↑, 1,   Smad1↓, 1,   Snail↓, 1,   TGF-β↓, 2,   TIMP1↑, 2,   TIMP2↑, 1,   TumCI↓, 6,   TumCMig↓, 6,   TumCP↓, 6,   TumMeta↓, 3,   TumMeta↑, 1,   Twist↓, 3,   uPA↓, 2,   VEGFR1↓, 1,   Zeb1↑, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 7,   ATF4↑, 1,   EGFR↓, 3,   EPR↑, 1,   Hif1a↓, 3,   VEGF↓, 9,  

Barriers & Transport(tgid=15) ⓘ

P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 3,   COX2↓, 4,   COX2↑, 1,   CXCR4↓, 1,   IL2↓, 1,   IL6↓, 2,   IL8↓, 1,   Imm↑, 3,   Inflam↓, 2,   NF-kB↓, 9,   PGE2↓, 1,   TNF-α↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 1,   ERα/ESR1↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 2,   ChemoSen↑, 8,   Dose?, 1,   Dose↑, 2,   Dose↝, 2,   eff↑, 10,   eff↝, 1,   RadioS↑, 3,   selectivity↓, 1,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALP↓, 1,   AST↓, 1,   BMPs↑, 2,   EGFR↓, 3,   ERα/ESR1↓, 1,   FOXM1↓, 1,   HER2/EBBR2↓, 2,   IL6↓, 2,   Ki-67↓, 1,   Myc↓, 1,   TP53↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 4,   antiNeop↑, 1,   AntiTum↑, 1,   cardioP↑, 10,   chemoP↑, 9,   ChemoSideEff↓, 1,   hepatoP↑, 2,   OS↓, 1,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 3,   toxicity↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,  
Total Targets: 223

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 4,   AntiBio↑, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 18,   Catalase↑, 12,   GPx↑, 5,   GPx1↑, 1,   GSH↑, 7,   GSR↓, 1,   GSTs↑, 3,   H2O2↓, 1,   HDL↑, 1,   HO-1↑, 8,   Keap1↑, 1,   lipid-P↓, 6,   MDA↓, 6,   MPO↓, 1,   NQO1↑, 1,   Nrf1↑, 1,   NRF2↓, 1,   NRF2↑, 13,   PrxII↑, 1,   RNS↓, 1,   ROS↓, 32,   ROS↑, 1,   mt-ROS↓, 1,   SIRT3↑, 4,   SOD↑, 11,   mt-SOD↑, 1,   SOD1↑, 1,   SOD2↑, 3,   TAC↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↓, 1,   ATP↑, 1,   DRP1/DNM1L↓, 1,   Insulin↓, 1,   mitResp↑, 2,   MMP↑, 1,   PGC-1α↓, 1,   PGC-1α↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   AMPK↑, 1,   cytoP450↓, 1,   glucose↓, 3,   LDH↓, 2,   LDL↓, 5,   NADPH↓, 2,   PPARγ↑, 3,   SIRT1↓, 1,   SIRT1↑, 3,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 3,   Apoptosis↓, 3,   BAX↓, 1,   Bax:Bcl2↓, 1,   Casp↓, 1,   Casp3↓, 3,   cl‑Casp8↑, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   iNOS↓, 5,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   other↓, 2,   other↝, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   HSP70/HSPA5↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   p16↓, 1,   P53↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

E2Fs↑, 1,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 2,   ERK↑, 1,   FOXO3↑, 1,   GSK‐3β↓, 3,   HDAC↓, 1,   IGF-1R↓, 1,   miR-34a↓, 1,   mTOR↓, 3,   neuroG↑, 1,   PTEN↓, 1,   STAT↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 3,   AP-1↓, 1,   APP↓, 1,   Ca+2?, 1,   MMP2↓, 2,   p‑Rac1↓, 1,   Rho↓, 1,   TGF-β↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

eNOS↑, 1,   NO↓, 3,   PDGFR-BB↓, 1,   TXA2↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 2,   GastroP↑, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 2,   COX2↓, 8,   CRP↓, 1,   IKKα↑, 1,   IL1↓, 1,   IL10↓, 4,   IL12↓, 1,   IL1β↓, 4,   IL2↓, 2,   IL4↓, 1,   IL6↓, 12,   IL8↓, 1,   Imm↑, 5,   INF-γ↓, 1,   Inflam↓, 29,   Inflam↑, 1,   JAK↓, 1,   NF-kB↓, 7,   PGE2↓, 3,   TLR1↓, 1,   TLR4↓, 1,   TNF-α↓, 12,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   GABA↑, 1,   tau↓, 2,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 5,   NLRP3↓, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 7,   BioAv↑, 16,   BioAv⇅, 1,   BioAv↝, 2,   Dose↝, 4,   eff↑, 2,   Half-Life↓, 1,   Half-Life↝, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALP↓, 1,   AST↓, 3,   BP↓, 5,   CRP↓, 1,   GutMicro↑, 9,   IL6↓, 12,   LDH↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 8,   AntiDiabetic↑, 8,   AntiTum↓, 1,   AntiTum↑, 1,   cardioP↓, 3,   cardioP↑, 38,   chemoP↑, 2,   cognitive↑, 7,   hepatoP↓, 1,   hepatoP↑, 8,   memory↑, 10,   neuroP↑, 20,   Obesity↓, 5,   OS↑, 4,   Pain↓, 2,   QoL↑, 1,   radioP↑, 4,   RenoP↑, 2,   Risk↓, 1,   toxicity↓, 4,   toxicity↑, 1,   toxicity↝, 4,   toxicity∅, 2,   Weight↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 2,   Bacteria↓, 3,   Sepsis↓, 2,  

Ingredients & Constituents(tgid=25) ⓘ

CA↑, 1,   Catechins↑, 1,   FA↑, 1,   GA↑, 1,   Phen↑, 1,   QC↑, 1,  
Total Targets: 180

Scientific Paper Hit Count for: cardioP, cardioProtective
13 doxorubicin
11 Lycopene
11 Quercetin
11 Thymoquinone
9 Allicin (mainly Garlic)
9 Resveratrol
8 Chlorogenic acid
8 EGCG (Epigallocatechin Gallate)
7 Carvacrol
7 Chrysin
6 Baicalein
6 Berberine
6 Cinnamon
5 Alpha-Lipoic-Acid
5 Coenzyme Q10
5 Curcumin
5 Honokiol
4 Aspirin
4 Atorvastatin
4 Centella asiatica / Gotu kola → asiaticoside
4 Chocolate
4 diet Fermented Foods
4 Sulforaphane (mainly Broccoli)
4 Silymarin (Milk Thistle) silibinin
3 Ashwagandha(Withaferin A)
3 Astaxanthin
3 Thymol-Thymus vulgaris
3 Choline
3 Spermidine
3 Crocetin
3 Diclofenac
3 Hydrogen Gas
3 Magnetic Fields
3 Rosmarinic acid
3 Urolithin
3 Vitamin K2
2 Baicalin
2 Beta-Caryophyllene
2 α-Bisabolol / Chamomile oil
2 Capsaicin
2 Hydroxycinnamic-acid
2 Selenium
2 Chemotherapy
2 Ellagic acid
2 Eugenol
2 Ferulic acid
2 Fisetin
2 Luteolin
2 Magnolol
2 Metformin
2 Piperine
2 Pterostilbene
2 Shikonin
1 1,8-Cineole
1 Anthocyanins
1 Astragalus
1 Apigenin (mainly Parsley)
1 Artemisinin
1 Aloe anthraquinones
1 Berbamine
1 Biochanin A
1 bempedoic acid
1 Betulinic acid
1 Boron
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Calorie Restriction Mimetics
1 Carvone
1 Cucurbitacin
1 Date Fruit Extract
1 Dihydrocaffeic Acid
1 diet Short Term Fasting
1 Dipyridamole
1 Dandelion Root
1 Emodin
1 Melatonin
1 Moringa oleifera
1 nicotinamide adenine dinucleotide
1 Naringin
1 Phenylbutyrate
1 Propolis -bee glue
1 Piperlongumine
1 Psoralidin
1 Rutin
1 Selenium NanoParticles
1 Shankhpushpi
1 Taurine
1 Ursolic acid
1 Vitamin B3,Niacin
1 Vitamin E
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1188  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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