cardioP Cancer Research Results

cardioP, cardioProtective: Click to Expand ⟱
Source:
Type:
CardioProtective


Scientific Papers found: Click to Expand⟱
3712- FA,    Ferulic Acid: A Hope for Alzheimer’s Disease Therapy from Plants
- Review, AD, NA
*antiOx↑, *Inflam↓, *ROS↓, *Aβ↓, *HO-1↑, *HSP70/HSPA5↑, *ERK↑, *Akt↑, *iNOS↓, *COX2↓, *cardioP↑, *memory↑, *IL2↓, *cognitive↑, *APP↓, *SOD↑, *Catalase↑, *Akt↑, *BioAv↑,
2846- FIS,    Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity
- in-vitro, Nor, NA
*cardioP↑, *ROS↓, *Casp↓, *DNAdam↓,
2828- FIS,    Fisetin, a Potent Anticancer Flavonol Exhibiting Cytotoxic Activity against Neoplastic Malignant Cells and Cancerous Conditions: A Scoping, Comprehensive Review
- Review, Var, NA
*neuroP↑, *antiOx↑, *Inflam↓, RenoP↑, COX2↓, Wnt↓, EGFR↓, NF-kB↓, Casp3↑, Ca+2↑, Casp8↑, TumCCA↑, CDK1↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, *P53↓, *P21↓, *p16↓, mTORC1↓, mTORC2↓, P53↑, P21↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, CDK4↓, BAX↑, Bcl-2↓, PCNA↓, HER2/EBBR2↓, Cyt‑c↑, MMP↓, cl‑Casp9↑, MMP2↓, MMP9↓, cl‑PARP↑, uPA↓, DR4↑, DR5↑, ROS↓, AIF↑, CDC25↓, Dose↑, CHOP↑, ROS↑, cMyc↓, cardioP↑,
2525- H2,    Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis
- in-vivo, NA, NA
OS↓, cardioP↑, *AST↓, ALAT↓, *ROS↓, *MDA↓, *hepatoP↑, *Inflam↓, chemoP↑,
2516- H2,    Hydrogen Gas in Cancer Treatment
- Review, Var, NA
*Half-Life↓, *ROS↓, *selectivity↑, *SOD↑, *HO-1↑, *NRF2↑, *chemoP↑, *radioP↑, ROS↑, *Inflam↓, eff↑, *TNF-α↓, *IL6↓, *cl‑Casp8↑, *Bax:Bcl2↓, *Apoptosis↓, *cardioP↑, *hepatoP↑, *RenoP↑, *chemoP↑, eff↝, chemoP↑, radioP↑, eff↑, TumCG↓, Ki-67↓, VEGF↓, selectivity↑,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
2868- HNK,    Honokiol: A review of its pharmacological potential and therapeutic insights
- Review, Var, NA - Review, Sepsis, NA
*P-gp↓, *ROS↓, *TNF-α↓, *IL10↓, *IL6↓, eIF2α↑, CHOP↑, GRP78/BiP↑, BAX↑, cl‑Casp9↑, p‑PERK↑, ER Stress↑, Apoptosis↑, MMPs↓, cFLIP↓, CXCR4↓, Twist↓, HDAC↓, BMPs↑, p‑STAT3↓, mTOR↓, EGFR↓, NF-kB↓, Shh↓, VEGF↓, tumCV↓, TumCMig↓, TumCI↓, ERK↓, Akt↓, Bcl-2↓, Nestin↓, CD133↓, p‑cMET↑, RAS↑, chemoP↑, *NRF2↑, *NADPH↓, *p‑Rac1↓, *ROS↓, *IKKα↑, *NF-kB↓, *COX2↓, *PGE2↓, *Casp3↓, *hepatoP↑, *antiOx↑, *GSH↑, *Catalase↑, *RenoP↑, *ALP↓, *AST↓, *ALAT↓, *neuroP↑, *cardioP↑, *HO-1↑, *Inflam↓,
2901- HNK,  doxoR,    Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts
- in-vivo, Nor, NA
*mitResp↑, *PPARγ↑, *Inflam↓, *ROS↓, *cardioP↑, *SOD2↑, *LDH↓,
2889- HNK,  doxoR,    Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice
- in-vivo, Nor, NA
*SIRT3↑, chemoP↑, *cardioP↑, mtDam↑, ROS↑, *ROS↓, *MMP↑,
2893- HNK,  doxoR,    Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts
- in-vivo, Nor, NA
*mitResp↑, *PPARγ↑, *cardioP↑, *SIRT3↑, *ROS↓, *GSH↑, *SOD2↑,
2894- HNK,    Pharmacological features, health benefits and clinical implications of honokiol
- Review, Var, NA - Review, AD, NA
*BioAv↓, *neuroP↑, *BBB↑, *ROS↓, *Keap1↑, *NRF2↑, *Casp3↓, *SIRT3↑, *Rho↓, *ERK↓, *NF-kB↓, angioG↓, RAS↓, PI3K↓, Akt↓, mTOR↓, *memory↑, *Aβ↓, *PPARγ↑, *PGC-1α↑, NF-kB↓, Hif1a↓, VEGF↓, HO-1↓, FOXM1↓, p27↑, P21↑, CDK2↓, CDK4↓, CDK6↓, cycD1/CCND1↓, Twist↓, MMP2↓, Rho↑, ROCK1↑, TumCMig↓, cFLIP↓, BMPs↑, OCR↑, ECAR↓, *AntiAg↑, *cardioP↑, *antiOx↑, *ROS↓, P-gp↓,
2926- LT,    Luteolin ameliorates rat myocardial ischemia-reperfusion injury through peroxiredoxin II activation: LUT's cardioprotection through PRX II
- in-vitro, Nor, H9c2
*cardioP↑, *PrxII↑,
2916- LT,    Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies
- Review, Var, NA - Review, AD, NA - Review, Park, NA
proCasp9↓, CDC2↓, CycB/CCNB1↓, Casp9↑, Casp3↑, Cyt‑c↑, cycA1/CCNA1↑, CDK2↓, APAF1↑, TumCCA↑, P53↑, BAX↑, VEGF↓, Bcl-2↓, Apoptosis↑, p‑Akt↓, p‑EGFR↓, p‑ERK↓, p‑STAT3↓, cardioP↑, Catalase↓, SOD↓, *BioAv↓, *antiOx↑, *ROS↓, *NO↓, *GSTs↑, *GSR↑, *SOD↑, *Catalase↑, *lipid-P↓, PI3K↓, Akt↓, CDK2↓, BNIP3↑, hTERT/TERT↓, DR5↑, Beclin-1↑, TNF-α↓, NF-kB↓, IL1↓, IL6↓, EMT↓, FAK↓, E-cadherin↑, MDM2↓, NOTCH↓, MAPK↑, Vim↓, N-cadherin↓, Snail↓, MMP2↓, Twist↓, MMP9↓, ROS↑, MMP↓, *AChE↓, *MMP↑, *Aβ↓, *neuroP↑, Trx1↑, ROS↓, *NRF2↑, NRF2↓, *BBB↑, ChemoSen↑, GutMicro↑,
3528- Lyco,    The Importance of Antioxidant Activity for the Health-Promoting Effect of Lycopene
- Review, Nor, NA - Review, AD, NA - Review, Park, NA
*antiOx↑, *ROS↓, *BioAv↝, *Half-Life↑, *BioAv↓, *BioAv↑, *cardioP↑, *neuroP↑, *H2O2↓, *VitC↑, *VitE↑, *GPx↑, *GSH↑, *MPO↓, *GSTs↓, *SOD↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL10↑, *MAPK↓, *Akt↓, *COX2↓, *TNF-α↓, *TGF-β1↑, *NO↓, *GSR↑, *NRF2↑, *HO-1↑, *TAC↑, *Inflam↓, *BBB↑, *neuroP↑, *memory↑,
3268- Lyco,    Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
- Review, AD, NA
*BioAv↓, *AntiCan↑, *ROCK1↓, *Ki-67↓, *ICAM-1↓, *cardioP↑, *antiOx↑, *NQO1↑, *HO-1↑, *TNF-α↓, *IL22↓, *NRF2↑, *NF-kB↓, *MDA↓, *Catalase↑, *SOD↑, *GSH↑, *cognitive↑, *tau↓, *hepatoP↑, *MMP2↑, *AST↓, *ALAT↓, *P450↑, *DNAdam↓, *ROS↓, *neuroP↑, *memory↑, *Ca+2↓, *Dose↝, *Dose↑, *Dose↝, *toxicity∅, PGE2↓, CDK2↓, CDK4↓, STAT3↓, NOX↓, NOX4↓, ROS↓, *SREBP1↓, *FASN↓, *ACC↓,
3264- Lyco,    Pharmacological potentials of lycopene against aging and aging‐related disorders: A review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *GSTs↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *iNOS↓, *NO↓, *TAC↑, *NOX4↓, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *IL1β↓, *TNF-α↓, *TLR2↓, *TLR4↓, *VCAM-1↓, *ICAM-1↓, *STAT3↓, *NF-kB↓, *ERK↓, *BP↓, ROS↓, PGE2↓, cardioP↑, *neuroP↑, *creat↓, *RenoP↑, *CRM↑,
3263- Lyco,    Lycopene protects against myocardial ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening
- in-vitro, Nor, H9c2 - in-vitro, Stroke, NA
*Apoptosis↓, *MMP↑, *Cyt‑c↓, *APAF1↓, *cl‑Casp9↓, *cl‑Casp3↓, *Bcl-2↑, *BAX↓, cardioP↑,
3261- Lyco,    Lycopene and Vascular Health
- Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiAg↑, *cardioP↑, *SOD↑, *Catalase↑, *ROS↓, *mtDam↓, *cardioP↑, *NF-kB↓, *NO↓, *COX2↓, *LDL↓, *eff↑, *ER Stress↓, *BioAv↑, *eff↑, *MMPs↓, *COX2↓, *RAGE↓,
3281- Lyco,  Chemo,    Lycopene Supplementation for Patients Under Cancer Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Review, Var, NA
eff↑, cardioP↑, eff?, PSA↓, RenoP↑,
4784- Lyco,    Protective effects of lycopene in cancer, cardiovascular, and neurodegenerative diseases: An update on epidemiological and mechanistic perspectives
- Review, Diabetic, NA - Review, CardioV, NA
*antiOx↑, *IL8↓, *IL6↓, *IL1↓, *NF-kB↓, Inflam↓, cycD1/CCND1↓, MMP2↓, MMP9↓, Bcl-2↓, NF-kB↓, *Nrf1↑, *antiOx↑, *BDNF↑, *neuroP↑, *cardioP↑, ROS↑, Dose↝,
4788- Lyco,    Lycopene as a potential anticancer agent: Current evidence on synergism, drug delivery systems and epidemiology (Review)
- Review, Var, NA
AntiCan↑, ChemoSen↑, chemoP↑, Dose↝, BioAv↑, BioAv↑, BioAv↓, cardioP↑, AntiDiabetic↑, hepatoP↑, neuroP↑, MAPK↓, MMP2↓, MMP9↓, TIMP1↑, TIMP2↑,
4801- Lyco,    Lycopene in the Prevention of Cardiovascular Diseases
- Review, CardioV, NA
*BioAv↝, *cardioP↑, *BioAv↑, *BioAv↑, *antiOx↑, *ROS↓, *ARE↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *COX2↓, *Inflam↓, *IL1β↓, *IL6↓, *IL8↑, *TNF-α↓, *NF-kB↓, *BP↓,
4796- Lyco,    The Anti-proliferation Effects of Lycopene on Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, Nor, MCF10
TumCG↓, selectivity↑, *BioAv↑, *antiOx↑, *ROS↓, Risk↓, *cardioP↑,
4528- MAG,    Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update
- Review, Nor, NA
*Inflam↑, *cardioP↑, *angioG↓, *antiOx↑, *neuroP↑, *Bacteria↓, AntiTum↑, TumCG↓, TumCMig↓, TumCI↓, Apoptosis↑, E-cadherin↑, NF-kB↓, TumCCA↑, cycD1/CCND1↓, PCNA↓, Ki-67↓, MMP2↓, MMP7↓, MMP9↓, TumCG↓, Casp3↑, NF-kB↓, Akt↓, mTOR↓, LDH↓, Ca+2↑, eff↑, *toxicity↓, *BioAv↝, *PGE2↓, *TLR2↓, *TLR4↓, *MAPK↓, *PPARγ↓,
5252- MAG,    Insights on the Multifunctional Activities of Magnolol
- Review, Var, NA
BioAv↓, *Inflam↓, *Bacteria↓, *antiOx↑, *neuroP↑, *cardioP↑, CYP1A1↓, *PPARγ↑, *NF-kB↓, *COX2↓, *iNOS↓, *ROS↓, Apoptosis↑, TumCCA↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, P21↑, TumCG↓, TumCMig↓, TumCI↓, Ki-67↓, PCNA↓, MMP2↓, MMP9↓, MMP7↓, DNAdam↑, MMP↓, TumCP↓, selectivity↑, PI3K↓, Akt↓, H2O2↓, Hif1a↓, *BDNF↑, *NRF2↑, *AChE↑,
4705- MEL,    Melatonin: beyond circadian regulation - exploring its diverse physiological roles and therapeutic potential
- Review, Nor, NA
*CLOCK↝, *BMD↑, *cardioP↑, *neuroP↑, *Sleep↑,
5785- MET,    Metformin improves healthspan and lifespan in mice
- in-vivo, Nor, NA
*AntiDiabetic↑, *AntiAge↑, *toxicity⇅, *CRM↑, *Strength↑, *LDL↓, *AMPK↑, *TAC↑, *ROS↓, *Inflam↓, Risk↓, *cardioP↑, *ALAT↓, *NRF2↑, *SOD2↑, *TrxR1↑, *NQO1↑, *NQO2↑,
5795- MET,    Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes
- Review, AD, NA - Review, Park, NA - Review, Diabetic, NA
*AntiDiabetic↑, *AMPK↑, *glyC↓, *ROS↓, *cardioP↑, *neuroP↑, *Half-Life↝, *toxicity↝, *BioAv↑, *glucose↓, *AGEs↓, AntiCan↑, Risk↓, TumCP↓, Apoptosis↑, TumCCA↑, cycD1/CCND1↓, pRB↓, p27↓, mTOR↓, Casp↑, ROS↑, MMP↓, ChemoSen↑, *hepatoP↑, *CRM↑, *Insulin↓,
4112- MF,    Novel protective effects of pulsed electromagnetic field ischemia/reperfusion injury rats
- in-vivo, Stroke, NA
*cardioP↑, *Bcl-2↑, *BAX↓, *ROS↓,
3467- MF,    Pulsed Magnetic Field Induces Angiogenesis and Improves Cardiac Function of Surgically Induced Infarcted Myocardium in Sprague-Dawley Rats
- in-vivo, Nor, NA
*angioG↑, *cardioP↑,
3482- MF,    Pulsed Electromagnetic Fields Increase Angiogenesis and Improve Cardiac Function After Myocardial Ischemia in Mice
- in-vitro, NA, NA
*cardioP↑, *VEGF↑, *VEGFR2↑, *Hif1a↑, *FGF↑, *ITGB1↑, *angioG↑,
3837- Moringa,    Moringa oleifera: A Tree of Life as a Promising Medicinal Plant for Neurodegenerative Diseases
- Review, AD, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *AntiTum↑, *hepatoP↑, *cardioP↑, *neuroP↑,
2933- NAD,    Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns
- Review, Nor, NA - NA, AD, NA - NA, Diabetic, NA - NA, Stroke, NA - NA, LiverDam, NA - NA, Park, NA
*mtDam↓, *BioAv↝, *BioAv↑, *OS↑, *eff↑, *eff↑, *cognitive↑, *DNAdam↓, *SIRT1↑, *cardioP↑, *ROS↓, *Dose↝, *BioAv↑, *hepatoP↑, *eff↑, *BG↓, *creat↓,
1798- NarG,    Naringenin: A potential flavonoid phytochemical for cancer therapy
- Review, NA, NA
*Inflam↓, *antiOx↓, neuroP↑, hepatoP↑, AntiCan↑, Apoptosis↑, TumCCA↑, angioG↓, ROS↝, SOD↑, TGF-β↓, Treg lymp↓, IL1β↓, *BioAv↝, ChemoSen↑, cardioP↑,
2042- PB,    Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury
- in-vitro, Nor, NA
*HDAC↓, *toxicity↓, *LDH↓, *SOD2↑, *ROS↓, *cardioP↑, *antiOx↑,
3252- PBG,    Propolis Extract and Its Bioactive Compounds—From Traditional to Modern Extraction Technologies
- Review, NA, NA
*Inflam↓, *TNF-α↓, *NF-kB↓, *MAPK↓, *ERK↓, *antiOx↑, *NRF2↑, *cardioP↑, *Glycolysis↑, *Ca+2↓, *HO-1↑, *NRF2↑, *neuroP↑,
5216- PI,  doxoR,    Piperine enhances doxorubicin sensitivity in triple-negative breast cancer by targeting the PI3K/Akt/mTOR pathway and cancer stem cells
- vitro+vivo, BC, MDA-MB-231
ChemoSen↑, necrosis↑, PTEN↓, PI3K↓, p‑Akt↓, mTOR↓, ALDH↓, TumVol↓, OS↑, cardioP↑, cl‑PARP↑,
3587- PI,    Piperine: A review of its biological effects
- Review, Park, NA - Review, AD, NA
*hepatoP↑, *Inflam↓, *neuroP↑, *antiOx↑, *angioG↑, *cardioP↑, *BioAv↑, *P450↓, *eff↑, *BioAv↑, E-cadherin↓, ER(estro)↓, MMP2↓, MMP9↓, VEGF↓, cMyc↓, BAX↑, P53↑, TumCG↓, OS↑, *cognitive↑, *GSK‐3β↓, *GSH↑, *Casp3↓, *Casp9↓, *Cyt‑c↓, *lipid-P↓, *motorD↑, *AChE↓, *memory↑, *cardioP↑, *ROS↓, *PPARγ↑, *ALAT↓, *AST↓, *ALP↓, *AMPK↑, *5HT↑, *SIRT1↑, *eff↑,
2948- PL,    The promising potential of piperlongumine as an emerging therapeutics for cancer
- Review, Var, NA
tumCV↓, TumCP↓, TumCI↓, angioG↓, EMT↓, TumMeta↓, *hepatoP↑, *lipid-P↓, *GSH↑, cardioP↑, CycB/CCNB1↓, cycD1/CCND1↓, CDK2↓, CDK1↓, CDK4↓, CDK6↓, PCNA↓, Akt↓, mTOR↓, Glycolysis↓, NF-kB↓, IKKα↓, JAK1↓, JAK2↓, STAT3↓, ERK↓, cFos↓, Slug↓, E-cadherin↑, TOP2↓, P53↑, P21↑, Bcl-2↓, BAX↑, Casp3↑, Casp7↑, Casp8↑, p‑HER2/EBBR2↓, HO-1↑, NRF2↑, BIM↑, p‑FOXO3↓, Sp1/3/4↓, cMyc↓, EGFR↓, survivin↓, cMET↓, NQO1↑, SOD2↑, TrxR↓, MDM2↓, p‑eIF2α↑, ATF4↑, CHOP↑, MDA↑, Ki-67↓, MMP9↓, Twist↓, SOX2↓, Nanog↓, OCT4↓, N-cadherin↓, Vim↓, Snail↓, TumW↓, TumCG↓, HK2↓, RB1↓, IL6↓, IL8↓, SOD1↑, RadioS↑, ChemoSen↑, toxicity↓, Sp1/3/4↓, GSH↓, SOD↑,
4968- PSO,    Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer
- in-vitro, Cerv, NA
*Inflam↓, *antiOx↑, *neuroP↑, *AntiDiabetic↑, *Bacteria↓, AntiTum↑, CSCs↓, ROS↑, TumAuto↑, Apoptosis↑, ChemoSen↑, RadioS↑, BioAv↓, *cardioP↑, *ROS↓, *LDH↓, TumCP↓, TRAIL⇅, TumCMig↓, EMT↓, NF-kB↓, P53↑, Casp3↑, NOTCH↓, CSCs↓, angioG↓, VEGF↓, Ki-67↓, CD31↓, TRAILR↑, MMP↓, BioAv↓, BioAv↑,
3930- PTS,    A Review of Pterostilbene Antioxidant Activity and Disease Modification
- Review, Var, NA - Review, adrenal, NA - Review, Stroke, NA
*BioAv↑, *antiOx↑, *neuroP↑, *Inflam↓, *ROS↓, *H2O2↓, *GSH↑, *GPx↑, *GSR↑, *SOD↑, TumCG↓, PTEN↑, HGF/c-Met↓, PI3K↓, Akt↓, NF-kB↓, TumMeta↓, MMP2↓, MMP9↓, Ki-67↓, Casp3↑, MMP↓, H2O2↑, ROS↑, ChemoSen↑, *cardioP↑, *CDK2↓, *CDK4↓, *cycE/CCNE↓, *cycD1/CCND1↓, *RB1↓, *PCNA↓, *CREB↑, *GABA↑, *memory↑, *IGF-1↑, *ERK↑, TIMP1↑, BAX↑, Cyt‑c↑, Diablo↑, SOD2↑,
3924- PTS,    Effect of resveratrol and pterostilbene on aging and longevity
- Review, AD, NA - Review, Stroke, NA
*antiOx↓, *ROS↑, *SOD↑, *GSH↑, *NRF2↑, *MDA↓, *HNE↓, *Inflam↓, *MAPK↓, *IL6↓, *TNF-α↓, *HO-1↑, *cardioP↑, *neuroP↑, *CRM↑, *NLRP3↓,
2303- QC,  doxoR,    Quercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1α in tumor and normal cells
- in-vitro, BC, 4T1 - in-vivo, NA, NA
cardioP↑, hepatoP↑, TumCG↓, OS↑, ChemoSen↑, chemoP↑, Hif1a↓, *Hif1a↑, selectivity↑, TumVol↓, OS↑,
98- QC,    Quercetin postconditioning attenuates myocardial ischemia/reperfusion injury in rats through the PI3K/Akt pathway
- in-vivo, Stroke, NA
*Bcl-2↑, *BAX↓, *Bax:Bcl2↓, *cardioP↑, *Akt↑, *PI3K↑, *LDH↓,
5025- QC,    New perspectives on the therapeutic potential of quercetin in non-communicable diseases: Targeting Nrf2 to counteract oxidative stress and inflammation
- Review, Nor, NA
*antiOx↑, *Inflam↓, *NRF2↓, *ROS↓, *cardioP↑, *HO-1↑, *Catalase↑, *GPx↑, *NQO1↑, *SIRT1↑,
3534- QC,  Lyco,    Synergistic protection of quercetin and lycopene against oxidative stress via SIRT1-Nox4-ROS axis in HUVEC cells
- in-vitro, Nor, HUVECs
*ROS↓, *NOX4↓, *Inflam↓, *NF-kB↓, *p65↓, *SIRT1↑, *cardioP↑, *IL6↓, *COX2↓,
3601- QC,    Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid
- Review, Var, NA - Review, AD, NA
*Inflam↓, *cardioP↑, AntiCan↑, AntiTum↑, *neuroP↑, *cognitive↑, *ROS↓, *BP↓, *LDL↓,
3354- QC,    Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine
- Review, Var, NA
*ROS↓, *IronCh↓, *lipid-P↓, *GSH↑, *NRF2↑, TumCCA↑, ER Stress↑, P53↑, CDK2↓, cycA1/CCNA1↓, CycB/CCNB1↓, cycE/CCNE↓, cycD1/CCND1↓, PCNA↓, P21↑, p27↑, PI3K↓, Akt↓, mTOR↓, STAT3↓, cFLIP↓, cMyc↓, survivin↓, DR5↓, *Inflam↓, *IL6↓, *IL8↓, COX2↓, 5LO↓, *cardioP↑, *FASN↓, *AntiAg↑, *MDA↓,
3353- QC,    Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells
- in-vitro, Oral, KON - in-vitro, Nor, MRC-5
tumCV↓, selectivity↑, TumCCA↑, TumCMig↓, TumCI↓, Apoptosis↑, TumMeta↓, Bcl-2↓, BAX↑, TIMP1↑, MMP2↓, MMP9↓, *Inflam↓, *neuroP↑, *cardioP↑, p38↓, MAPK↓, Twist↓, P21↓, cycD1/CCND1↓, Casp3↑, Casp9↑, p‑Akt↓, p‑ERK↓, CD44↓, CD24↓, ChemoSen↑, MMP↓, Cyt‑c↑, AIF↑, ROS↑, Ca+2↑, Hif1a↓, VEGF↓,
3347- QC,    Recent Advances in Potential Health Benefits of Quercetin
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *Inflam↓, TumCP↓, Apoptosis↑, *cardioP↑, *BP↓, TumMeta↓, MDR1↓, NADPH↓, ChemoSen↑, MMPs↓, TIMP2↑, *NLRP3↓, *IFN-γ↑, *COX2↓, *NF-kB↓, *MAPK↓, *CRP↓, *IL6↓, *TNF-α↓, *IL1β↓, *TLR4↑, *PKCδ↓, *AP-1↓, *ICAM-1↓, *NRF2↑, *HO-1↑, *lipid-P↓, *neuroP↑, *eff↑, *memory↑, *cognitive↑, *AChE↓, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑,

Showing Research Papers: 101 to 150 of 202
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 202

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↓, 1,   CYP1A1↓, 1,   GSH↓, 1,   H2O2↓, 1,   H2O2↑, 1,   HO-1↓, 1,   HO-1↑, 1,   MDA↑, 1,   NOX4↓, 1,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↓, 4,   ROS↑, 9,   ROS↝, 1,   SOD↓, 1,   SOD↑, 2,   SOD1↑, 1,   SOD2↑, 2,   Trx1↑, 1,   TrxR↓, 1,  

Mitochondria & Bioenergetics ⓘ

AIF↑, 2,   CDC2↓, 1,   CDC25↓, 1,   MMP↓, 7,   mtDam↑, 1,   OCR↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   cMyc↓, 4,   ECAR↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   LDH↓, 1,   NADPH↓, 1,  

Cell Death ⓘ

Akt↓, 9,   p‑Akt↓, 3,   APAF1↑, 1,   Apoptosis↑, 9,   BAX↑, 7,   Bcl-2↓, 6,   BIM↑, 1,   Casp↑, 1,   Casp3↑, 7,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 2,   cl‑Casp9↑, 2,   proCasp9↓, 1,   cFLIP↓, 3,   Cyt‑c↑, 4,   Diablo↑, 1,   DR4↑, 1,   DR5↓, 1,   DR5↑, 2,   HGF/c-Met↓, 1,   hTERT/TERT↓, 1,   MAPK↓, 3,   MAPK↑, 1,   MDM2↓, 2,   necrosis↑, 1,   p27↓, 1,   p27↑, 2,   p38↓, 1,   survivin↓, 2,   TRAIL⇅, 1,   TRAILR↑, 1,  

Kinase & Signal Transduction ⓘ

HER2/EBBR2↓, 1,   p‑HER2/EBBR2↓, 1,   Sp1/3/4↓, 2,  

Transcription & Epigenetics ⓘ

pRB↓, 1,   tumCV↓, 3,  

Protein Folding & ER Stress ⓘ

CHOP↑, 3,   eIF2α↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 2,   GRP78/BiP↑, 1,   p‑PERK↑, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,   BNIP3↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   P53↑, 6,   cl‑PARP↑, 2,   PCNA↓, 5,  

Cell Cycle & Senescence ⓘ

CDK1↓, 2,   CDK2↓, 8,   CDK4↓, 4,   cycA1/CCNA1↓, 3,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 3,   cycD1/CCND1↓, 9,   cycE/CCNE↓, 1,   P21↓, 1,   P21↑, 5,   RB1↓, 1,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State ⓘ

ALDH↓, 1,   CD133↓, 1,   CD24↓, 1,   CD44↓, 1,   cFos↓, 1,   cMET↓, 1,   p‑cMET↑, 1,   CSCs↓, 2,   EMT↓, 3,   ERK↓, 2,   p‑ERK↓, 2,   FOXM1↓, 1,   p‑FOXO3↓, 1,   HDAC↓, 1,   mTOR↓, 8,   mTORC1↓, 1,   mTORC2↓, 1,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 2,   OCT4↓, 1,   PI3K↓, 7,   PTEN↓, 1,   PTEN↑, 1,   RAS↓, 1,   RAS↑, 1,   Shh↓, 1,   SOX2↓, 1,   STAT3↓, 3,   p‑STAT3↓, 2,   TOP2↓, 1,   TumCG↓, 10,   Wnt↓, 1,  

Migration ⓘ

5LO↓, 1,   Ca+2↑, 3,   CD31↓, 1,   E-cadherin↓, 1,   E-cadherin↑, 3,   FAK↓, 1,   Ki-67↓, 6,   MMP2↓, 10,   MMP7↓, 2,   MMP9↓, 10,   MMPs↓, 2,   N-cadherin↓, 2,   Rho↑, 1,   ROCK1↑, 1,   Slug↓, 1,   Snail↓, 2,   TGF-β↓, 1,   TIMP1↑, 3,   TIMP2↑, 2,   Treg lymp↓, 1,   TumCI↓, 5,   TumCMig↓, 6,   TumCP↓, 5,   TumMeta↓, 4,   Twist↓, 5,   uPA↓, 1,   Vim↓, 2,  

Angiogenesis & Vasculature ⓘ

angioG↓, 4,   ATF4↑, 1,   EGFR↓, 3,   p‑EGFR↓, 1,   Hif1a↓, 4,   VEGF↓, 7,  

Barriers & Transport ⓘ

P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 2,   CXCR4↓, 1,   IKKα↓, 1,   IL1↓, 1,   IL1β↓, 1,   IL6↓, 2,   IL8↓, 1,   Inflam↓, 1,   JAK1↓, 1,   JAK2↓, 1,   NF-kB↓, 10,   PGE2↓, 2,   PSA↓, 1,   TNF-α↓, 1,  

Cellular Microenvironment ⓘ

NOX↓, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 2,   ER(estro)↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 4,   BioAv↑, 3,   ChemoSen↑, 11,   Dose↑, 1,   Dose↝, 2,   eff?, 1,   eff↑, 4,   eff↝, 1,   MDR1↓, 1,   RadioS↑, 2,   selectivity↑, 5,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   BMPs↑, 2,   EGFR↓, 3,   p‑EGFR↓, 1,   FOXM1↓, 1,   GutMicro↑, 1,   HER2/EBBR2↓, 1,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 1,   IL6↓, 2,   Ki-67↓, 6,   LDH↓, 1,   PSA↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 4,   AntiDiabetic↑, 1,   AntiTum↑, 3,   cardioP↑, 11,   chemoP↑, 6,   hepatoP↑, 3,   neuroP↑, 2,   OS↓, 1,   OS↑, 4,   radioP↑, 1,   RenoP↑, 2,   Risk↓, 3,   toxicity↓, 1,   TumVol↓, 2,   TumW↓, 1,  
Total Targets: 219

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 2,   antiOx↑, 24,   ARE↑, 1,   Catalase↑, 9,   GPx↑, 4,   GPx1↑, 1,   GSH↑, 10,   GSR↑, 3,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 2,   HNE↓, 1,   HO-1↑, 11,   Keap1↑, 1,   lipid-P↓, 7,   MDA↓, 6,   MPO↓, 1,   NOX4↓, 2,   NQO1↑, 3,   Nrf1↑, 1,   NRF2↓, 1,   NRF2↑, 15,   PrxII↑, 1,   ROS↓, 33,   ROS↑, 1,   mt-ROS↓, 1,   SIRT3↑, 4,   SOD↑, 10,   SOD2↑, 4,   TAC↑, 3,   TrxR1↑, 1,   VitC↑, 1,   VitE↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↓, 1,  

Mitochondria & Bioenergetics ⓘ

Insulin↓, 1,   mitResp↑, 2,   MMP↑, 3,   mtDam↓, 2,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACC↓, 1,   ALAT↓, 4,   AMPK↑, 3,   CREB↑, 1,   CRM↑, 4,   FASN↓, 2,   glucose↓, 1,   glyC↓, 1,   Glycolysis↑, 1,   LDH↓, 4,   LDL↓, 4,   NADPH↓, 2,   PPARγ↓, 1,   PPARγ↑, 5,   SIRT1↑, 5,   SREBP1↓, 1,  

Cell Death ⓘ

Akt↓, 2,   Akt↑, 3,   APAF1↓, 1,   Apoptosis↓, 2,   BAX↓, 3,   Bax:Bcl2↓, 2,   Bcl-2↑, 3,   Casp↓, 1,   Casp3↓, 3,   cl‑Casp3↓, 1,   cl‑Casp8↑, 1,   Casp9↓, 1,   cl‑Casp9↓, 1,   Cyt‑c↓, 2,   iNOS↓, 3,   MAPK↓, 5,  

Transcription & Epigenetics ⓘ

other↓, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,   HSP70/HSPA5↑, 1,   NQO2↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 3,   p16↓, 1,   P53↓, 1,   PCNA↓, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   P21↓, 1,   RB1↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

CLOCK↝, 1,   ERK↓, 3,   ERK↑, 2,   FGF↑, 1,   FOXO3↑, 1,   GSK‐3β↓, 1,   HDAC↓, 1,   IGF-1↑, 1,   mTOR↓, 1,   PI3K↑, 1,   PTEN↓, 1,   STAT3↓, 1,  

Migration ⓘ

AntiAg↑, 4,   AP-1↓, 1,   APP↓, 1,   Ca+2↓, 2,   ITGB1↑, 1,   Ki-67↓, 1,   MMP2↑, 1,   MMPs↓, 1,   PKCδ↓, 1,   p‑Rac1↓, 1,   RAGE↓, 1,   Rho↓, 1,   ROCK1↓, 1,   TGF-β1↑, 1,   VCAM-1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   angioG↑, 3,   Hif1a↑, 2,   NO↓, 5,   VEGF↑, 1,   VEGFR2↑, 1,  

Barriers & Transport ⓘ

BBB↑, 3,   P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 9,   CRP↓, 1,   ICAM-1↓, 3,   IFN-γ↑, 1,   IKKα↑, 1,   IL1↓, 2,   IL10↓, 1,   IL10↑, 1,   IL1β↓, 5,   IL2↓, 1,   IL22↓, 1,   IL6↓, 11,   IL8↓, 3,   IL8↑, 1,   Inflam↓, 25,   Inflam↑, 1,   NF-kB↓, 12,   p65↓, 1,   PGE2↓, 2,   TLR2↓, 2,   TLR4↓, 3,   TLR4↑, 1,   TNF-α↓, 10,  

Synaptic & Neurotransmission ⓘ

5HT↑, 1,   AChE↓, 3,   AChE↑, 1,   BDNF↑, 2,   GABA↑, 1,   tau↓, 1,  

Protein Aggregation ⓘ

AGEs↓, 1,   Aβ↓, 3,   NLRP3↓, 3,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 4,   BioAv↑, 17,   BioAv↝, 5,   Dose↑, 1,   Dose↝, 3,   eff↑, 8,   Half-Life↓, 1,   Half-Life↑, 1,   Half-Life↝, 1,   P450↓, 1,   P450↑, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 4,   ALP↓, 2,   AST↓, 4,   BG↓, 1,   BMD↑, 1,   BP↓, 4,   creat↓, 2,   CRP↓, 1,   IL6↓, 11,   Ki-67↓, 1,   LDH↓, 4,   RAGE↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 1,   AntiCan↑, 1,   AntiDiabetic↑, 3,   AntiTum↑, 1,   cardioP↑, 41,   chemoP↑, 2,   cognitive↑, 7,   hepatoP↑, 9,   memory↑, 8,   motorD↑, 1,   neuroP↑, 23,   OS↑, 1,   radioP↑, 1,   RenoP↑, 3,   Sleep↑, 1,   Strength↑, 1,   toxicity↓, 2,   toxicity⇅, 1,   toxicity↝, 1,   toxicity∅, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 3,   Sepsis↓, 1,  
Total Targets: 198

Scientific Paper Hit Count for: cardioP, cardioProtective
11 doxorubicin
11 Lycopene
11 Quercetin
11 Thymoquinone
9 Allicin (mainly Garlic)
9 Resveratrol
8 Chlorogenic acid
7 Carvacrol
6 Baicalein
6 Berberine
6 EGCG (Epigallocatechin Gallate)
5 Alpha-Lipoic-Acid
5 Chrysin
5 Coenzyme Q10
5 Honokiol
4 Aspirin -acetylsalicylic acid
4 Atorvastatin
4 Chocolate
4 Sulforaphane (mainly Broccoli)
4 Silymarin (Milk Thistle) silibinin
3 Ashwagandha(Withaferin A)
3 Astaxanthin
3 Thymol-Thymus vulgaris
3 Choline
3 Cinnamon
3 Spermidine
3 Hydrogen Gas
3 Magnetic Fields
3 Rosmarinic acid
3 Urolithin
3 Vitamin K2
2 Baicalin
2 Capsaicin
2 Selenium
2 Chemotherapy
2 Ferulic acid
2 Fisetin
2 Luteolin
2 Magnolol
2 Metformin
2 Piperine
2 Pterostilbene
2 Shikonin
1 Anthocyanins
1 Astragalus
1 Apigenin (mainly Parsley)
1 Artemisinin
1 Aloe anthraquinones
1 Berbamine
1 Biochanin A
1 bempedoic acid
1 Betulinic acid
1 Boron
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Calorie Restriction Mimetics
1 Hydroxycinnamic-acid
1 Curcumin
1 diet Short Term Fasting
1 Dipyridamole
1 Ellagic acid
1 Emodin
1 Melatonin
1 Moringa oleifera
1 nicotinamide adenine dinucleotide
1 Naringin
1 Phenylbutyrate
1 Propolis -bee glue
1 Piperlongumine
1 Psoralidin
1 Rutin
1 Selenium NanoParticles
1 Shankhpushpi
1 Taurine
1 Ursolic acid
1 Vitamin B3,Niacin
1 Vitamin E
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1188  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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