Aβ Cancer Research Results

Aβ, Aβ aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (Aβ): In Alzheimer’s disease, Aβ peptides tend to misfold and aggregate into oligomers and fibrils.
Scientific Papers found: Click to Expand⟱
3782- FA,    Ferulic acid ameliorates bisphenol A (BPA)-induced Alzheimer’s disease-like pathology through Akt-ERK crosstalk pathway in male rats
- in-vivo, AD, NA
*cognitive↑, *ERK↓, *p‑Akt↓, *AChE↓, *BACE↓, *neuroP↑, *ROS↓, *MDA↓, *GSH↑, *GSSG↓, *p‑tau↓, *lipid-P↓, *Aβ↓,
3779- FA,    A review on ferulic acid and analogs based scaffolds for the management of Alzheimer’s disease
- Review, AD, NA
*antiOx↑, *neuroP↑, *Aβ↓, *Inflam↓, *COX2↓, *Casp↓, *NOS2↓, *HO-1↑, *AChE∅, *BChE∅, *memory↑,
3778- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer’s Disease: A Narrative Review
- Review, AD, NA
*neuroP↑, *Aβ↓, *antiOx↑, *Inflam↓, *ROS↓, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK?, *hepatoP↑, *TLR4↓, *PPARγ↑, *NRF2↑, *Fenton↓, *IronCh↑, *MDA↓, *HO-1↑, *Bil↑, *GCLC↑, *GCLM↑, *NQO1↑, *GutMicro↑, *SOD↑, *Ca+2↓, *lipid-P↓, *PGE2↓,
3710- FA,    Therapeutic Potential of Ferulic Acid in Alzheimer's Disease
- Review, AD, NA
*antiOx↑, *AntiCan↑, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *Aβ↓, *ROS↓, *AChE↓,
3711- FA,    A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease
- Review, AD, NA
*antiOx↑, *neuroP↑, *Aβ↓, *Inflam↓, *AChE↓, *IronCh↑,
3712- FA,    Ferulic Acid: A Hope for Alzheimer’s Disease Therapy from Plants
- Review, AD, NA
*antiOx↑, *Inflam↓, *ROS↓, *Aβ↓, *HO-1↑, *HSP70/HSPA5↑, *ERK↑, *Akt↑, *iNOS↓, *COX2↓, *cardioP↑, *memory↑, *IL2↓, *cognitive↑, *APP↓, *SOD↑, *Catalase↑, *Akt↑, *BioAv↑,
3713- FA,    Protective Effect of Ferulic Acid on Acetylcholinesterase and Amyloid Beta Peptide Plaque Formation in Alzheimer’s Disease: An In Vitro Study
- Review, AD, NA
*AChE↓, *antiOx↑, *neuroP↑, *Aβ↓, *MMP↓, *XO↓, *SOD↑, *lipid-P↑, *ROS↓,
3714- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK↓, *p38↓, *JNK↓, *IL6↓, *IL8↓, *hepatoP↑, *RenoP↑, *Catalase↑, *PPARγ↑, *ROS↓, *Fenton↓, *IronCh↑, *SOD↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ARE↑, *Bil↑, *radioP↑, *GCLC↑, *GCLM↑, *NQO1↑, *Half-Life↝, *GutMicro↑, *Aβ↓, *BDNF↑, *Ca+2↓, *lipid-P↓, *PGE2↓, *cognitive↑, *ChAT↑, *memory↑, *Dose↝, *toxicity↓,
3715- FA,  CUR,  PS,    The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice
- in-vivo, AD, NA
*cognitive↑, *IL1β↓, *Ach↑, *Aβ↓, *p‑tau↓, *BDNF↑, *APP↓,
3717- FA,    Neuroprotective Properties of Ferulic Acid in Preclinical Models of Alzheimer's Disease: A Systematic Literature Review
- Review, AD, NA
*toxicity↓, *BBB↑, *Aβ↓, *antiOx↑, *Inflam↓, *neuroP↑,
2861- FIS,    The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
- Review, Nor, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *Aβ↓, *12LOX↓, *COX2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑, *BDNF↑,
4107- FLS,  Ex,    Combined effects of aerobic exercise and 40-Hz light flicker exposure on early cognitive impairments in Alzheimer's disease of 3×Tg mice
- in-vivo, AD, NA
*Aβ↓, *cognitive↑, *Inflam↓, *eff↑,
4018- FulvicA,  Fe,    Inhibitory Impacts of Fulvic Acid-Coated Iron Oxide Nanoparticles on the Amyloid Fibril Aggregations
- in-vivo, AD, NA
*Inflam↓, *Aβ↓,
3723- Gb,    Can We Use Ginkgo biloba Extract to Treat Alzheimer’s Disease? Lessons from Preclinical and Clinical Studies
- Review, AD, NA
*memory↑, *antiOx↑, *Casp3↓, *APP↓, *AChE↓, *Aβ↓, *5HT↑, *SOD↓, *MDA↓, *NO↓, *GSH↑, *Bcl-2↑, *BAX↑, *TNF-α↓, *IL1β↑, *iNOS↓, *IL10↓, *p‑tau↓, *ROS↓, *MAOB↓, *cognitive↑, *neuroP↑, *Apoptosis↓,
3721- Gb,    Ginkgo biloba Extract in Alzheimer’s Disease: From Action Mechanisms to Medical Practice
- Review, AD, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSR↑, *MMP↑, *Inflam↓, *Aβ↓, *memory↑, *Dose↝, *BBB↑, *neuroP↑,
4004- Gins,    Effects of fermented ginseng on memory impairment and β-amyloid reduction in Alzheimer’s disease experimental models
- in-vivo, AD, NA
*memory↑, *Aβ↓,
4003- Gins,    Neuroprotective Potentials of Panax Ginseng Against Alzheimer's Disease: A Review of Preclinical and Clinical Evidences
- Review, adrenal, NA
*neuroP↑, *Inflam↓, *ROS↓, *BACE↓, *PPARγ↑, *Aβ↓, *p‑tau↓, *NF-kB↓, *IL1β↓, *IL6↓, *TNF-α↓, *ROS↓, *CREB↓, *BDNF↑, *memory↑,
3829- Gins,    Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease
- Review, AD, NA
*cognitive↑, *neuroP↑, *Aβ↓, *tau↓, *PI3K↑, *Akt↑, *memory↑,
4302- Gins,    Panax ginseng: A modulator of amyloid, tau pathology, and cognitive function in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *Aβ↓, *p‑tau↓, *cognitive↑, *eff↑, *PKA↑, *CREB↑, *BACE↓, *ADAM10↑, *MAPK↑, *ERK↑, *PI3K↑, *Akt↑, *NRF2↑, *PPARγ↓, *IDE↑, *APP↓, *PP2A↑, *memory↑,
3772- H2,    Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *Inflam↓, *ROS↓, *GutMicro↑, *TNF-α↓, *IL6↓, *IL1β↓, *IL10↓, *Catalase↑, *GSH↑,
3774- H2,    The role of hydrogen in Alzheimer’s disease
- Review, AD, NA
*Inflam↓, *antiOx↑, *NLRP3↓, *memory↑, *Aβ↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *p‑p38↓, *JNK↓, *ROS↓, *cognitive↑, *ER(estro)↑, *BDNF↑,
3764- H2,    Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model
- in-vivo, AD, NA
*memory↑, *Aβ↓, *p‑tau↓, *BAX↓, *ROS↓, *NO↓, *Ca+2↓, *MDA↓, *Catalase↓, *GPx↓, *TNF-α↓, *Bcl-2↑, *VEGF↑, *Inflam↓, *cognitive↑,
3767- H2,    The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges
- Review, AD, NA
*Inflam↓, *neuroP↑, *toxicity↓, *antiOx↑, *ROS↓, *NLRP3↓, *IL1β↓, *mtDam↓, *ATP↑, *AMPK↑, *FOXO3↑, *SOD1↑, *Catalase↑, *NRF2↑, *NO↓, *MDA↓, *lipid-P↓, *memory↑, *ER(estro)↓, *BDNF↑, *cognitive↑, *APP↓, *BACE↓, *Aβ↓, *BP∅, *BBB↑,
4307- H2,    Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models
- in-vivo, AD, NA
*cognitive↑, *Inflam↓, *ROS↓, *neuroP↑, *memory↑, *BBB↑, *BDNF↑, *TNF-α↓, *Catalase↑, *IL6↓, *Aβ↓, *GABA↓, *Dose↝,
3769- H2S,    Research progress of hydrogen sulfide in Alzheimer's disease from laboratory to hospital: a narrative review
- Review, AD, NA
*APP↓, *Apoptosis↓, *Inflam↓, *antiOx↑, *BP↓, *NLRP3↓, *ROS↓, *Aβ↓, *ER Stress↓,
2869- HNK,    Nature's neuroprotector: Honokiol and its promise for Alzheimer's and Parkinson's
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *motorD↑, *Aβ↓, *p‑tau↓, *cognitive↑, *memory↑, *ERK↑, *p‑Akt↑, *PPARγ↑, *PGC-1α↑, *MMP↑, *mt-ROS↓, *SIRT3↑, *IL1β↓, *TNF-α↓, *GRP78/BiP↓, *CHOP↓, *NF-kB↓, *GSK‐3β↓, *β-catenin/ZEB1↑, *Ca+2↓, *AChE↓, *SOD↑, *Catalase↑, *GPx↑,
2894- HNK,    Pharmacological features, health benefits and clinical implications of honokiol
- Review, Var, NA - Review, AD, NA
*BioAv↓, *neuroP↑, *BBB↑, *ROS↓, *Keap1↑, *NRF2↑, *Casp3↓, *SIRT3↑, *Rho↓, *ERK↓, *NF-kB↓, angioG↓, RAS↓, PI3K↓, Akt↓, mTOR↓, *memory↑, *Aβ↓, *PPARγ↑, *PGC-1α↑, NF-kB↓, Hif1a↓, VEGF↓, HO-1↓, FOXM1↓, p27↑, P21↑, CDK2↓, CDK4↓, CDK6↓, cycD1/CCND1↓, Twist↓, MMP2↓, Rho↑, ROCK1↑, TumCMig↓, cFLIP↓, BMPs↑, OCR↑, ECAR↓, *AntiAg↑, *cardioP↑, *antiOx↑, *ROS↓, P-gp↓,
4238- HNK,    Neuropharmacological potential of honokiol and its derivatives from Chinese herb Magnolia species: understandings from therapeutic viewpoint
- Review, AD, NA - NA, Park, NA
*BDNF↑, *hepatoP↑, *ALAT↓, *AST↓, *TNF-α↓, *SIRT3↑, *Aβ↓, *Apoptosis↓, *ROS↓, *MMP↑, *Ca+2↓, *Casp3↓, *Ach↑, *PPARγ↑, *PGC-1α↑, *motorD↑, *TNF-α↓, *IL1β↓,
2916- LT,    Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies
- Review, Var, NA - Review, AD, NA - Review, Park, NA
proCasp9↓, CDC2↓, CycB/CCNB1↓, Casp9↑, Casp3↑, Cyt‑c↑, cycA1/CCNA1↑, CDK2↓, APAF1↑, TumCCA↑, P53↑, BAX↑, VEGF↓, Bcl-2↓, Apoptosis↑, p‑Akt↓, p‑EGFR↓, p‑ERK↓, p‑STAT3↓, cardioP↑, Catalase↓, SOD↓, *BioAv↓, *antiOx↑, *ROS↓, *NO↓, *GSTs↑, *GSR↑, *SOD↑, *Catalase↑, *lipid-P↓, PI3K↓, Akt↓, CDK2↓, BNIP3↑, hTERT/TERT↓, DR5↑, Beclin-1↑, TNF-α↓, NF-kB↓, IL1↓, IL6↓, EMT↓, FAK↓, E-cadherin↑, MDM2↓, NOTCH↓, MAPK↑, Vim↓, N-cadherin↓, Snail↓, MMP2↓, Twist↓, MMP9↓, ROS↑, MMP↓, *AChE↓, *MMP↑, *Aβ↓, *neuroP↑, Trx1↑, ROS↓, *NRF2↑, NRF2↓, *BBB↑, ChemoSen↑, GutMicro↑,
4295- LT,    Luteolin Reduces Alzheimer’s Disease Pathologies Induced by Traumatic Brain Injury
- in-vivo, AD, NA
*Aβ↓, *GSK‐3β↓, *p‑tau↓, *BBB↑,
4292- LT,    Luteolin for neurodegenerative diseases: a review
- Review, AD, NA - Review, Park, NA - Review, MS, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↝, *BBB↑, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL33↓, *NF-kB↓, *BACE↓, *ROS↓, *SOD↑, *HO-1↑, *NRF2↑, *Casp3↓, *Casp9↑, *Bax:Bcl2↓, *UPR↑, *GRP78/BiP↑, *Aβ↓, *GSK‐3β↓, *tau↓, *CREB↑, *ATP↑, *cognitive↑, *BloodF↑, *BDNF↑, *TrkB↑, *memory↑, *PPARγ↑, *eff↑,
3977- Lut,  Zeax,    Dietary carotenoids related to risk of incident Alzheimer dementia (AD) and brain AD neuropathology: a community-based cohort of older adults
- Trial, AD, NA
*Aβ↓, *cognitive↑, *Mood↑,
3532- Lyco,    Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer’s disease
- in-vitro, AD, NA
*ROS↓, *PI3K↑, *Akt↑, *NRF2↑, *antiOx↑, *Aβ↓, *Apoptosis↓, *neuroP↑,
3900- MCT,    Coconut (Cocos nucifera) Ethanolic Leaf Extract Reduces Amyloid-β (1-42) Aggregation and Paralysis Prevalence in Transgenic Caenorhabditis elegans Independently of Free Radical Scavenging and Acetylcholinesterase Inhibition
- in-vitro, AD, NA
*ROS↑, *AChE↓, *Aβ↓,
3898- MCT,    Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer's disease
- Review, AD, NA
*neuroP↑, *cognitive↑, *Aβ↓, *Inflam↓, *ROS↓,
4106- MF,    Cognitive Decline: Current Intervention Strategies and Integrative Therapeutic Approaches for Alzheimer's Disease
- Review, AD, NA
*cognitive↑, *memory↑, *Aβ↓, *neuroP↑,
4118- MF,    Effects of transcranial magnetic stimulation on neurobiological changes in Alzheimer's disease
- Review, AD, NA
*cognitive↑, *BDNF↑, *neuroP↑, *memory↑, *ROS↓, *antiOx↑, *Aβ↓, *eff↑,
4119- MF,    Therapeutic potential and mechanisms of repetitive transcranial magnetic stimulation in Alzheimer’s disease: a literature review
- Review, AD, NA
*cognitive↑, *memory↑, *motorD↑, *eff↑, *eff↑, *Dose↝, *Dose↝, *Dose↝, *BDNF↑, *Aβ↓, *eff↑,
3740- MF,    Gamma rhythm low field magnetic stimulation alleviates neuropathologic changes and rescues memory and cognitive impairments in a mouse model of Alzheimer's disease
- in-vivo, AD, NA
*cognitive↑, *Dose↝, *Aβ↓, *PSD95↑,
3739- MF,    Early intervention using long-term rhythmic pulsed magnetic stimulation alleviates cognitive decline in a 5xFAD mouse model of Alzheimer's disease
- in-vivo, AD, NA
*memory↑, *cognitive↑, *Aβ↓, *FGF↑,
3735- MF,    Examining the effects of extremely low-frequency magnetic fields on cognitive functions and functional brain markers in aged mice
- in-vivo, AD, NA
*APP∅, *Aβ∅, *Inflam∅, *memory∅,
3725- MF,    Short-term effects of extremely low frequency electromagnetic fields exposure on Alzheimer's disease in rats
- in-vivo, AD, NA
*Weight∅, *memory∅, *cognitive∅, *Aβ∅,
3488- MFrot,  MF,    Rotating magnetic field improves cognitive and memory impairments in APP/PS1 mice by activating autophagy and inhibiting the PI3K/AKT/mTOR signaling pathway
- in-vivo, AD, NA
*cognitive↑, *memory↑, *neuroP↑, *Aβ↓, *PI3K↓, *Akt↓, *mTOR↓,
3489- MFrot,  MF,    Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer's disease mice.
- in-vivo, AD, NA
*Aβ↓, *motorD↑, *cognitive↑, *memory↑, *ROS↓,
3745- MFrot,  MF,    The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *5HT↑, *cFos↑, *Aβ↓, *memory↑, *BDNF↑, *Ach↑, *AChE↓, *cognitive↑, *BDNF↑, *NGF↑, *β-catenin/ZEB1↑, *p‑Akt↓, *mTOR↓, *MMP1↓, *MMP9↓, *MMP-10↓, *TIMP1↑, *TIMP2↑,
212- MFrot,  MF,    Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer’s disease mice
- in-vivo, AD, SH-SY5Y
*β-Amyloid↓, *cognitive↑, *motorD↑, *ROS↓, *memory↑, *Aβ?,
204- MFrot,  MF,    Rotating magnetic field improved cognitive and memory impairments in a sporadic ad model of mice by regulating microglial polarization
- in-vivo, AD, NA
*NF-kB↓, *MAPK↓, *TLR4↓, *memory↑, *cognitive↑, *TGF-β1↑, *ARG↑, *IL4↑, *IL10↑, *IL6↓, *IL1↓, *TNF-α↓, *iNOS↓, *ROS↓, *NO↓, *MyD88↓, *p‑IKKα↓, *p‑IκB↓, *p‑p65↓, *p‑JNK↓, *p‑p38↓, *ERK↓, *neuroP↑, *Aβ↓,
3834- Moringa,    Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *Aβ↓, *BACE↓, *cal2↓, *p‑tau↓, *ROS↓, *SOD↑, *MDA↓, *cognitive↑, *memory↑,
3835- Moringa,    Moringa Oleifera Alleviates Aβ Burden and Improves Synaptic Plasticity and Cognitive Impairments in APP/PS1 Mice
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *AChE↓, *neuroP↑, *Mood↑, *cognitive↑, *memory↑, *Aβ↓, *BACE↓, *AEP↓, *IDE↑, *NEP↑, *LRP1↑, *PSD95↑, *STEP↓, *APP↓,
3848- MSM,    Modulatory effect of methylsulfonylmethane against BPA/γ-radiation induced neurodegenerative alterations in rats: Influence of TREM-2/DAP-12/Syk pathway
- in-vitro, AD, NA
*ROS↓, *Inflam↓, *neuroP↑, *ER(estro)↑, *NRF2↑, *HO-1↑, *Trx1↑, *TXNIP↓, *MDA↓, *NOX↓, *GSH↑, *GPx↑, *SOD↑, *Catalase↑, *BDNF↑, *AChE↓, *p‑tau↓, *Aβ↓,

Showing Research Papers: 101 to 150 of 264
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 264

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↓, 1,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↓, 1,   ROS↑, 1,   SOD↓, 1,   Trx1↑, 1,  

Mitochondria & Bioenergetics ⓘ

CDC2↓, 1,   MMP↓, 1,   OCR↑, 1,  

Core Metabolism/Glycolysis ⓘ

ECAR↓, 1,  

Cell Death ⓘ

Akt↓, 2,   p‑Akt↓, 1,   APAF1↑, 1,   Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,   Casp9↑, 1,   proCasp9↓, 1,   cFLIP↓, 1,   Cyt‑c↑, 1,   DR5↑, 1,   hTERT/TERT↓, 1,   MAPK↑, 1,   MDM2↓, 1,   p27↑, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,   BNIP3↑, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 3,   CDK4↓, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,   p‑ERK↓, 1,   FOXM1↓, 1,   mTOR↓, 1,   NOTCH↓, 1,   PI3K↓, 2,   RAS↓, 1,   p‑STAT3↓, 1,  

Migration ⓘ

E-cadherin↑, 1,   FAK↓, 1,   MMP2↓, 2,   MMP9↓, 1,   N-cadherin↓, 1,   Rho↑, 1,   ROCK1↑, 1,   Snail↓, 1,   TumCMig↓, 1,   Twist↓, 2,   Vim↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   p‑EGFR↓, 1,   Hif1a↓, 1,   VEGF↓, 2,  

Barriers & Transport ⓘ

P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL1↓, 1,   IL1β↓, 1,   IL6↓, 1,   NF-kB↓, 3,   TNF-α↓, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↝, 1,   ChemoSen↑, 1,  

Clinical Biomarkers ⓘ

BMPs↑, 1,   p‑EGFR↓, 1,   FOXM1↓, 1,   GutMicro↑, 1,   hTERT/TERT↓, 1,   IL6↓, 1,  

Functional Outcomes ⓘ

cardioP↑, 1,   cognitive↑, 1,  
Total Targets: 80

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 21,   ARE↑, 1,   Bil↑, 2,   Catalase↓, 1,   Catalase↑, 10,   Fenton↓, 2,   GCLC↑, 2,   GCLM↑, 2,   GPx↓, 1,   GPx↑, 2,   GSH↑, 5,   GSR↑, 2,   GSSG↓, 1,   GSTs↑, 1,   HO-1↑, 6,   Keap1↑, 1,   lipid-P↓, 7,   lipid-P↑, 1,   MDA↓, 8,   NQO1↑, 2,   NRF2↑, 9,   ROS↓, 31,   ROS↑, 1,   mt-ROS↓, 1,   SIRT3↑, 3,   SOD↓, 1,   SOD↑, 11,   SOD1↑, 1,   Trx1↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 3,  

Mitochondria & Bioenergetics ⓘ

ATP↑, 2,   MMP↓, 1,   MMP↑, 4,   mtDam↓, 1,   PGC-1α↑, 3,  

Core Metabolism/Glycolysis ⓘ

12LOX↓, 1,   ALAT↓, 1,   AMPK↑, 2,   CREB↓, 1,   CREB↑, 2,   PPARγ↓, 1,   PPARγ↑, 7,   SIRT1↑, 1,  

Cell Death ⓘ

Akt↓, 1,   Akt↑, 5,   p‑Akt↓, 2,   p‑Akt↑, 1,   Apoptosis↓, 4,   BAX↓, 1,   BAX↑, 1,   Bax:Bcl2↓, 1,   Bcl-2↑, 2,   Casp↓, 1,   Casp3↓, 4,   Casp9↑, 1,   iNOS↓, 5,   JNK↓, 2,   p‑JNK↓, 1,   MAPK↓, 1,   MAPK↑, 1,   p‑MAPK?, 1,   p‑MAPK↓, 1,   p38↓, 1,   p‑p38↓, 2,  

Transcription & Epigenetics ⓘ

Ach↑, 3,  

Protein Folding & ER Stress ⓘ

CHOP↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↑, 1,   UPR↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

cFos↑, 1,   ERK↓, 3,   ERK↑, 3,   FGF↑, 1,   FOXO3↑, 2,   GSK‐3β↓, 3,   mTOR↓, 2,   PI3K↓, 1,   PI3K↑, 3,  

Migration ⓘ

AntiAg↑, 1,   APP↓, 7,   APP∅, 1,   ARG↑, 1,   Ca+2↓, 5,   cal2↓, 1,   LRP1↑, 1,   MMP-10↓, 1,   MMP1↓, 1,   MMP9↓, 1,   PKA↑, 1,   Rho↓, 1,   TGF-β1↑, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TXNIP↓, 1,   VCAM-1↓, 2,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature ⓘ

NO↓, 5,   NO↑, 1,   VEGF↑, 1,  

Barriers & Transport ⓘ

BBB↑, 9,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 5,   ICAM-1↓, 2,   p‑IKKα↓, 1,   IL1↓, 1,   IL10↓, 2,   IL10↑, 1,   IL1β↓, 9,   IL1β↑, 1,   IL2↓, 1,   IL33↓, 1,   IL4↑, 1,   IL6↓, 6,   IL6↑, 1,   IL8↓, 2,   Inflam↓, 25,   Inflam∅, 1,   p‑IκB↓, 1,   MyD88↓, 1,   NF-kB↓, 7,   p‑p65↓, 1,   PGE2↓, 2,   TLR4↓, 2,   TNF-α↓, 13,  

Cellular Microenvironment ⓘ

NOX↓, 1,  

Synaptic & Neurotransmission ⓘ

5HT↑, 2,   AChE↓, 11,   AChE∅, 1,   ADAM10↑, 1,   BChE∅, 1,   BDNF↑, 14,   ChAT↑, 1,   GABA↓, 1,   NGF↑, 1,   PSD95↑, 2,   tau↓, 2,   p‑tau↓, 10,   TrkB↑, 1,  

Protein Aggregation ⓘ

AEP↓, 1,   Aβ?, 1,   Aβ↓, 47,   Aβ∅, 2,   BACE↓, 7,   IDE↑, 2,   MAOB↓, 1,   NEP↑, 1,   NLRP3↓, 5,   PP2A↑, 1,   XO↓, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors ⓘ

ER(estro)↓, 1,   ER(estro)↑, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 1,   BioAv↝, 1,   Dose↝, 7,   eff↑, 8,   Half-Life↝, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   AST↓, 1,   Bil↑, 2,   BloodF↑, 1,   BP↓, 1,   BP∅, 1,   GutMicro↑, 3,   IL6↓, 6,   IL6↑, 1,   NOS2↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   cardioP↑, 3,   cognitive↑, 29,   cognitive∅, 1,   hepatoP↑, 4,   memory↑, 27,   memory∅, 2,   Mood↑, 2,   motorD↑, 5,   neuroP↑, 30,   radioP↑, 1,   RenoP↑, 1,   STEP↓, 1,   toxicity↓, 3,   toxicity↑, 1,   Weight∅, 1,  
Total Targets: 185

Scientific Paper Hit Count for: Aβ, Aβ aggregation
19 Selenium NanoParticles
17 Curcumin
14 Resveratrol
14 Urolithin
12 Magnetic Fields
11 Ferulic acid
8 Berberine
8 EGCG (Epigallocatechin Gallate)
8 Chlorogenic acid
8 Thymoquinone
7 Alpha-Lipoic-Acid
7 Quercetin
7 Rosmarinic acid
6 EMF
5 Ashwagandha(Withaferin A)
5 Carnosine
5 Crocetin
5 Hydrogen Gas
5 Magnetic Field Rotating
5 Mushroom Lion’s Mane
5 Rutin
5 Sulforaphane (mainly Broccoli)
4 Apigenin (mainly Parsley)
4 Capsaicin
4 Cinnamon
4 Folic Acid, Vit B9
4 Ginseng
4 Silymarin (Milk Thistle) silibinin
4 Vitamin B1/Thiamine
3 beta-carotene(VitA)
3 Honokiol
3 Luteolin
3 Radio Frequency
3 Vitamin B3,Niacin
3 Vitamin B5,Pantothenic Acid
3 Vitamin K2
2 Aromatherapy
2 Huperzine A/Huperzia serrata
2 Bacopa monnieri
2 borneol
2 Boron
2 Boswellia (frankincense)
2 α-Bisabolol / Chamomile oil
2 Vitamin E
2 diet Short Term Fasting
2 D-limonene
2 Eugenol
2 Ginkgo biloba
2 MCToil
2 Moringa oleifera
2 chitosan
2 Taurine
2 Vitamin D3
1 1,8-Cineole
1 Anthocyanins
1 Astaxanthin
1 Caffeic acid
1 Carnosic acid
1 Celastrol
1 Choline
1 Chrysin
1 Coenzyme Q10
1 Rivastigmine
1 Galantamine
1 Cysteamine
1 Emodin
1 Phosphatidylserine
1 Fisetin
1 Flickering Light Stimulation
1 Exercise
1 Shilajit/Fulvic Acid
1 Iron
1 hydrogen sulfide
1 Lutein
1 Zeaxanthin
1 Lycopene
1 Methylsulfonylmethane
1 Nimbolide
1 Piperine
1 Piperlongumine
1 Salvia officinalis
1 S-adenosyl-L-methionine
1 Carvacrol
1 Sesame seeds and Oil
1 Silicic Acid
1 Spermidine
1 Ursolic acid
1 Vitamin A, Retinoic Acid
1 Vitamin B12
1 Vitamin B2,Riboflavin
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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