AntiDiabetic Cancer Research Results

AntiDiabetic, AntiDiabetic: Click to Expand ⟱
Source:
Type:
AntiDiabetic
Scientific Papers found: Click to Expand⟱
8205- LGE,    Citral: Bioactivity, Metabolism, Delivery Systems, and Food Preservation Applications
- Review, Nor, NA
*CompStab↓, *Bacteria↓, *antiOx↑, *Inflam↓, *AntiDiabetic↑, *AntiCan↑,
8200- LGE,    Chemical Properties and Therapeutic Potential of Citral, a Monoterpene Isolated from Lemongrass
- Review, Var, NA
*AntiBio↑, *antiOx↑, *AntiCan↑, *AntiDiabetic↑, *Inflam↓, Dose↝, BioAv↝,
8292- lign,    Anticancer potential of flaxseed lignans, their metabolites and synthetic counterparts in relation with molecular targets: current challenges and future perspectives
- Review, Var, NA
*BioAv↝, chemoPv↑, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, *AntiDiabetic↑, *antiOx↑, *AntiCan↑, *Inflam↓, *cardioP↑, TumCCA↑, PSA↓, miR-106b↓, IGF-1↓, ERK↓, Akt↓, Bcl-2↓, p‑FAK↓, radioP↑, P-gp/ABCB1↓, ChemoSen↑, MMP↓, ROS↑, BioAv↓, *toxicity↓, chemoP↑,
8295- lign,    Distribution, biosynthesis and therapeutic potential of lignans
- Review, Var, NA
*Ingr?, *BioAv↝, *antiOx↑, *AntiCan↑, *Inflam↓, *other?, Dose↝, AntiTum↑, pS2/TFF1↓, Bcl-2↓, IGF-1R↓, *radioP↑, *HO-1↑, GSTM1↑, NQO1↑, ChemoSen↑, *AntiDiabetic↑, *glucose↓, *GSH↑, *SOD↑, *MDA↓, *NO↓, *Bacteria↓, *AntiFungal↑,
8311- lign,    The Power of Lignans: Plant Compounds with Multifaceted Health-Promoting Effects
- Review, Nor, NA
*cardioP↑, *AntiDiabetic↑, *Obesity↓, *Bacteria↓, *AntiFungal↑, *AntiViral↑, *neuroP↑, *antiOx↑, *lipid-P↓, *memory↑, *CREB↑, *BDNF↑, *PSD95↑, *β-Amyloid↓, *TNF-α↓, *IL6↓, *IL10↓, *GutMicro↑, *Endoglin↑, *END↑, *cognitive↑, *Akt↓, *IκB↓, *NF-kB↓, *HO-1↑, *VEGF↑, *p‑eNOS↑, *GRP78/BiP↓, *PERK↓, *ATF4↓, *CHOP/DDIT3↓, *SREBP1/SREBF1↓, *ROS↓, TumVol↓,
8377- LT,    Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases
- Review, Asthma, NA
*PI3K↑, *Akt↑, *Inflam↓, *ROS↓, *BioAv↓, *RenoP↑, *cardioP↑, *neuroP↑, *antiAll↑, *AntiDiabetic↑, *hepatoP↑, *AntiThr↑, *toxicity↓, *IL10↓, *Sepsis↓, *TNF-α↓, *ROS↓, *GSH↑, *Catalase↑, *SOD↑, *MDA↓, *lipid-P↓, *IL4↓, *IL5↓, *PGE2↓, *PI3K↑, *Akt↑, *mTOR↑, *Beclin-1/ATG6↓, *Mucositis↓, *PLA2↓, STAT3↓, PD-L1↓, miR-34a↓, Casp3↑, Casp9↑, Bcl-2↓, BAX↑, Bax:Bcl2↑, Apoptosis↑, ROS↑, EMT↓, E-cadherin↓, DR5↑, LIMK1↓, Pain↓,
4788- Lyco,    Lycopene as a potential anticancer agent: Current evidence on synergism, drug delivery systems and epidemiology (Review)
- Review, Var, NA
AntiCan↑, ChemoSen↑, chemoP↑, Dose↝, BioAv↑, BioAv↑, BioAv↓, cardioP↑, AntiDiabetic↑, hepatoP↑, neuroP↑, MAPK↓, MMP2↓, MMP9↓, TIMP1↑, TIMP2↑,
4529- MAG,    Effectiveness of Magnolol, a Lignan from Magnolia Bark, in Diabetes, Its Complications and Comorbidities—A Review
- Review, Diabetic, NA
*AntiDiabetic↑, *glucose↓, *SOD↑, *Catalase↑, *ROS↓, *MDA↓, *GPx↑, *CYP2E1↓, *AGEs↓, *IL10↑, *neuroP↑, *GutMicro↑,
8556- Matr,    Matrine alleviates spatial learning and memory impairment in diabetic mice by inhibiting endoplasmic reticulum stress and through modulation of PK2/PKRs pathway
- in-vivo, AD, NA - in-vivo, Diabetic, NA
*AntiTum↑, *AntiDiabetic↑, *cardioP↑, *neuroP↑, *glucose↓, *Learn↑, *memory↑, *ER Stress↓, *GRP78/BiP↓, *CHOP/DDIT3↓, *ATF6↓, *Casp12↓, *PROK2↑, *PROKR1↑, *PROKR2↑,
5785- MET,    Metformin improves healthspan and lifespan in mice
- in-vivo, Nor, NA
*AntiDiabetic↑, *AntiAge↑, *toxicity⇅, *CRM↑, *Strength↑, *LDL↓, *AMPK↑, *TAC↑, *ROS↓, *Inflam↓, Risk↓, *cardioP↑, *ALAT↓, *NRF2↑, *SOD2↑, *TrxR1↑, *NQO1↑, *NQO2↑,
5795- MET,    Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes
- Review, AD, NA - Review, Park, NA - Review, Diabetic, NA
*AntiDiabetic↑, *AMPK↑, *glyC↓, *ROS↓, *cardioP↑, *neuroP↑, *Half-Life↝, *toxicity↝, *BioAv↑, *glucose↓, *AGEs↓, AntiCan↑, Risk↓, TumCP↓, Apoptosis↑, TumCCA↑, cycD1/CCND1↓, pRB↓, p27/CDKN1B↓, mTOR↓, Casp↑, ROS↑, MMP↓, ChemoSen↑, *hepatoP↑, *CRM↑, *Insulin↓,
5800- MET,    Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect
- Review, Var, NA
ChemoSen↑, RadioS↑, Imm↑, *AntiDiabetic↑, *AMPK↑, TumCP↓, hepatoP↑, ATP↓, AMP↑, glucoNG↓, ROS↑, compI↓, DNAdam↑, CSCs↓, NP/CIPN↓, chemoP↑, toxicity↓, Trx↓, Synergy↑, cycD1/CCND1↓, CDK4↓, CDK6↓, cycE/CCNE↓, CDK2↓,
9159- MG, MIC-1,    A Comprehensive Review of Germination Impact on Moringa Seeds and Sprouts: Physiological and Biochemical Changes, Bioactive Compounds, Health Benefits, and Food Applications
- Review, Nor, NA
*eff↑, *Ingr↝, *antiOx↑, *Inflam↓, *AntiDiabetic↑, *hepatoP↑, *ROS↓, *other↑,
8912- MO,    Anticancer effect of Moringa oleifera in oral squamous cell carcinoma: a systematic review
- Review, Oral, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *chemoPv↑, *Ingr↝, *AntiDiabetic↑, *hepatoP↑, *Bacteria↓, *AntiFungal↑, Apoptosis↑, ROS↑, DNAdam↑, Casp3↑, TumCCA↑, ROS↓, chemoP↑,
8913- MO,    Moringa oleifera Lamk. as a Promising Adjunct Therapeutic Candidate: A Narrative Review of Human Studies and Published Case Reports
- Review, Var, NA
*Imm↑, *antiOx↑, *AntiDiabetic↑, *Ingr↝, *Ingr↝, *TAC↑, *IL6↓, *Sleep↑,
8922- MP,    A Comprehensive Review of the Therapeutic Potential of Mucuna Pruriens
- Review, Park, NA
*Inflam↓, *AntiBio↑, *neuroP?, *Ingr↝, *Ingr↝, *AntiDiabetic↑, *hepatoP↑, *Imm↑, *Dose?, *neuroP↑, *glucose↓,
8919- MP,    Antineoplastic Effects of Mucuna pruriens Against Human Colorectal Adenocarcinoma
- in-vitro, CRC, COLO205
*AntiDiabetic↑, *antiOx↑, *antiNeop↑, antiOx↑, Dose↝, Apoptosis↑, TumCCA?,
8942- MushCha,    Therapeutic properties of Inonotus obliquus (Chaga mushroom): A review
- Review, Nor, NA
*Inflam↓, *antiOx↑, *AntiCan↑, *AntiDiabetic↑, *Obesity↓, *hepatoP↑, *RenoP↑, *fatigue↓, *Bacteria↓, *AntiViral↑, *toxicity↓, Ingr↝,
8960- mushLions,    Recent Advances in Erinacine A: Preparation, Biological Activities, and Biosynthetic Pathway
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *NGF↑, *other↝, *antiOx↑, *Inflam↓, *antiCG↑, *Bacteria↓, *hyperG↝, *AntiDiabetic↑, *AntiCan↑, *neuroG↑, *cognitive↑, *Stroke↓, *IL1β↓, *IL6↓, *TNF-α↓, *RNS↓, *iNOS↓, *MAPK↓, *CHOP/DDIT3↓, TumCD↓, ROS↑, TumCP↓, TumCI↓, ROCK1↓, LIMK2↓, Cofilin↓, PI3K↓, mTOR↓, P70S6K↓, TumCMig↓, TumMeta↓, TGF-β↓, MMP9↓, *AntiAge↑, *RIP1↓, *cl‑Casp8↓, *cl‑Casp3↓, *NRF2↑, *HO-1↑, *SOD1↑,
6775- Neem,  Nimb,    Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment
- Review, Nor, NA
*antiOx↑, P53↑, PTEN↑, NF-kB↓, PI3K↓, Akt↓, Bcl-2↓, VEGF↓, *Inflam↓, *COX2/PTGS2↓, *5LO↝, *Wound Healing↑, *Imm↑, *hepatoP↑, *AntiDiabetic↑, *neuroP↑, *AntiViral↑, *Bacteria↑, *AntiBio↑, *AntiFungal↑, cMyc↓, BAX↓, IAP1↓, IAP2/BIRC3↓, Bcl-xL↓, survivin↓, XIAP↓, angioG↓,
6486- Nimb,    Nimbolide: promising agent for prevention and treatment of chronic diseases
- Review, Var, NA - Review, AD, NA
*other↝, *Inflam↓, AntiCan↑, *Bacteria↓, *AntiViral↑, *neuroP↑, *hepatoP↑, *ROS?, *NRF2↑, *HO-1↑, *TLR4↓, *NF-kB↓, *AChE↓, *Aβ↓, *GSK‐3β↓, *LDL↓, *DNAdam↓, *lipid-P↓, *antiOx↑, *SOD1↑, *GSH↑, *IL6↓, *IL1β↓, *STAT3↓, *GPx↑, *Catalase↑, *MDA↓, *AntiDiabetic↑, *HDL↓, *MCP1/CCL2↓, *VEGF↓, *MMP9↓, *GutMicro↑, TumCP↓, TumCCA↑, TumCMig↓, NF-kB↓, ROS↑, PI3K↓, Akt↓, mTOR↓, ERK↓, EMT↓, TumMeta↓, ChemoSen↑, eff↑, selectivity↑, CDK4↓, CDK6↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, MMP2↓, Sp1/3/4↓, AP-1↓, P21↑, *AntiArt↑, *IL23↓, *IL17↓, *IFN-γ↓, *HSP70/HSPA5↓,
8434- OM,    Traditional use, phytochemistry, toxicology, and pharmacology of Origanum majorana L
- Review, Var, NA
*Bacteria↓, *AntiFungal↑, *antiOx↑, *AntiP↑, *AntiDiabetic↑, *AntiCan↑, *RenoP↑, *Inflam↓, *Analgesic↑, *antiPy↑, *antiM↑, *Ingr↝, *Ingr↝, *creat↓, *Urea↓, *uricA↓, *BUN↓, *ALAT↓, *AST↓, *ALP↓, *Catalase↑, *SOD↑, *GSTA1↑,
8986- PCorn,    Health Benefits of Purple Corn (Zea mays L.) Phenolic Compounds
- Review, Nor, NA
antiOx↑, Inflam↓, AntiCan↑, angioG↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑,
8987- PCorn,    A comprehensive review on purple corn kernels: phytochemical composition, bioactivity, bioaccessibility, health benefits, and industry applications
- Review, Nor, NA
*Ingr↑, *GutMicro↑, *AntiDiabetic↑, *cardioP↑, *antiOx↑, *Inflam↓, *AntiCan↑, *neuroP↑, *Imm↝,
4968- PSO,    Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer
- in-vitro, Cerv, NA
*Inflam↓, *antiOx↑, *neuroP↑, *AntiDiabetic↑, *Bacteria↓, AntiTum↑, CSCs↓, ROS↑, TumAuto↑, Apoptosis↑, ChemoSen↑, RadioS↑, BioAv↓, *cardioP↑, *ROS↓, *LDH↓, TumCP↓, TRAIL⇅, TumCMig↓, EMT↓, NF-kB↓, P53↑, Casp3↑, NOTCH↓, CSCs↓, angioG↓, VEGF↓, Ki-67↓, CD31/PECAM-1↓, TRAILR↑, MMP↓, BioAv↓, BioAv↑,
3335- QC,    Recent advances on the improvement of quercetin bioavailability
- Review, Nor, NA
*BioAv↓, *antiOx↑, *antiAll↑, *AntiDiabetic↑,
4827- QC,  CUR,    Synthetic Pathways and the Therapeutic Potential of Quercetin and Curcumin
- Review, Var, NA
*AntiCan↑, *Inflam↓, *Bacteria↓, *AntiDiabetic↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *NRF2↑, *Trx↑, *IronCh↑, *MDA↑, cycD1/CCND1↓, PI3K↓, Casp3↑, BAX↑, ChemoSen↑, ROS↑, Synergy↑, MMP↓, Cyt‑c↑, Akt↓, ERK↓,
7954- RT,    Rutin : therapeutic potential and recent advances in drug delivery
- Review, Nor, NA - Review, IBD, NA
*antiOx↑, *antiAll↑, *Inflam↓, *AntiTum↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *AntiArt↑, *PLA2↓, *chemoP↑, *ROS↓, *Casp3↓, *TNF-α↓, *NF-kB↓, *cardioP↑, *Stroke↓, *TG/TAG↓, *FFA/NEFA↓, *LDL↓, *HDL↑, *AntiDiabetic↑, *MPO↓, *NF-kB↓, *BioAv↓, *BioAv↝,
4603- SeNPs,    Therapeutic applications of selenium nanoparticles
- Review, Var, NA
AntiCan↑, Imm↑, *AntiDiabetic↑, *antiOx↑, *Inflam↓, ROS↑, ER Stress↑, DNAdam↑, *toxicity↓, *eff↑, *BioAv↑, selectivity↑, TumCCA↑, Risk↓, *lipid-P↓, *TNF-α↓, *CRP↓, TumMeta↓, angioG↓, selectivity↑, Synergy↑, *Synergy↑,
4457- SeNPs,    Selenium nanoparticles: a review on synthesis and biomedical applications
- Review, Var, NA - NA, Diabetic, NA
*BioAv↑, *toxicity↓, *eff↑, chemoPv↑, *Inflam↓, antiOx↑, *selenoP↑, *ROS↓, *Dose↝, AntiCan↑, *Bacteria↓, eff↑, DNAdam↑, selectivity↑, *AntiDiabetic↑,
5904- TV,    Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Obesity, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2/PTGS2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,
5018- UA,    Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies
- Review, Var, NA
Inflam↓, TumCCA↑, chemoPv↑, TumMeta↓, antiOx↑, AntiViral↑, AntiDiabetic↑,
5021- UA,    Anticancer effect of ursolic acid via mitochondria-dependent pathways
- Review, Var, NA
Inflam↓, TNF-α↓, IL6↓, IL17↓, NF-kB↓, COX2/PTGS2↓, *AntiDiabetic↑, *hepatoP↑, ALAT↓, AST↓, TumCP↓, Apoptosis↑, TumCCA↑, TumAuto↑, tumCV↓, TumCMig↓, Glycolysis↓, ATP↓, lactateProd↓, HK2↓, PKA↓, COX2/PTGS2↓, mtDam↑, Casp3↑, Casp8↑, Casp9↑, Akt↓, ROS↑, MMP↓, P53↑,
7887- VT,  IVT,    Dietary Flavonoids Vitexin and Isovitexin: New Insights into Their Functional Roles in Human Health and Disease Prevention
- Review, AD, NA - Review, Var, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *Bacteria↓, *neuroP↑, *Obesity↓, *cardioP↑, *ROS↓, *MMP↑, *ATP↑, *MFN2↑, *DRP1/DNM1L↓, *FOXO3↑, *NRF2↑, *Ferroptosis↓, *GPx4↑, TumCP↓, HMGB1↓, PI3K↓, Akt↓, Hif1a↓, CDK1↓, CycB/CCNB1↓, TumCCA↑, Apoptosis↑, P53↑, NF-kB↓, ERK↓, p‑PI3K↓, miR-34a↑, Apoptosis↑, CSCs?, *MAPK↓, *HO-1↑, *hepatoP↑, *AMPK↑, *Akt↑, *GSK‐3β↑, *chemoP↑, *Casp3↓, *IRes↝, *GlucoseCon↑, ChemoSen↑, *GSH↑, *SOD↑, *ATF2↑, *GPx↑, *GSTs↑, *AntiAge↑, *Stroke↓, *AChE↓, *ACE/ACE1↓, *ACE2↓, *GutMicro↑, *MPO↓, *H+/K+-ATPase↓, *AntiDiabetic↑, *GLUT4↑, *Obesity↓, *HH↓, *RenoP↑, *BioAv↓, *BioAv↝, *BioAv↑,
9151- WN,    Antioxidant and Anti-Inflammatory Properties of Walnut Constituents: Focus on Personalized Cancer Prevention and the Microbiome
- Review, Var, NA - Review, Col, NA
Ingr↝, GutMicro↑, Inflam↓, Imm↑, *cardioP↑, *AntiDiabetic↑, *AntiAge↑, Risk↓, Ingr↝, RANTES↓, eff↑, IL10↓, TumW↓, Risk↓, Risk↓,

Showing Research Papers: 101 to 135 of 135
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 135

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 6,   Catalase↓, 1,   Catalase↑, 1,   GSH↑, 1,   GSTs↑, 1,   H2O2↑, 1,   HO-1↑, 1,   lipid-P↓, 1,   lipid-P↑, 3,   MDA↑, 1,   NQO1↑, 1,   NRF2↑, 1,   ROS↓, 4,   ROS↑, 31,   ROS↝, 1,   i-ROS↑, 2,   SOD↓, 1,   SOD↑, 1,   Trx↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   mitResp↓, 1,   mtDam↑, 3,   mt-OXPHOS↓, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   AMP↑, 1,   ATP↓, 4,   FASN↓, 1,   glucoNG↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 5,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   p‑GSK‐3β↓, 2,   HK2↓, 1,   lactateProd↓, 1,   LDL↓, 1,   PDK1 / PDPK1↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 1,   APAF1↑, 1,   Apoptosis↓, 2,   Apoptosis↑, 39,   BAD↑, 1,   BAX↓, 1,   BAX↑, 15,   Bax:Bcl2↓, 1,   Bax:Bcl2↑, 6,   Bcl-2↓, 16,   Bcl-2↑, 1,   Bcl-xL↓, 2,   Casp↑, 2,   Casp1↑, 1,   Casp12↝, 1,   Casp3↑, 26,   cl‑Casp3↑, 3,   proCasp3↓, 1,   Casp7↑, 5,   cl‑Casp7↑, 1,   Casp8↑, 6,   Casp9↑, 16,   cl‑Casp9↑, 2,   Cyt‑c↑, 10,   DR5↑, 1,   Fas↑, 1,   IAP1↓, 2,   IAP2/BIRC3↓, 1,   iNOS↓, 1,   Mcl-1↓, 2,   MDM2↑, 1,   p‑MDM2↓, 1,   MOMP↑, 1,   p38↑, 1,   p‑p38↑, 1,   pS2/TFF1↓, 1,   PUMA↑, 1,   survivin↓, 2,   TRAIL⇅, 1,   TRAILR↑, 1,   TumCD↓, 1,   TumCD↑, 4,   XIAP↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 24,   Akt↑, 2,   p‑Akt↓, 3,   EGFR↓, 4,   ERK↓, 12,   ERK↑, 1,   p‑ERK↓, 2,   HER2/EBBR2↓, 1,   IGF-1R↓, 1,   IGFR↓, 1,   JAK↓, 1,   JAK1↑, 1,   JNK↓, 2,   JNK↑, 1,   p‑JNK↑, 1,   LIMK1↓, 1,   MAPK↓, 5,   MEK↓, 2,   mTOR↓, 10,   p‑mTOR↓, 1,   P70S6K↓, 1,   PI3K↓, 23,   p‑PI3K↓, 1,   PKA↓, 1,   PKCδ↓, 1,   PTEN↑, 2,   RAS↓, 2,   Sp1/3/4↓, 1,   STAT↓, 1,   STAT3↓, 6,   STK11/LKB1↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 1,   p‑cJun↑, 1,   cMyc↓, 4,   DNMT3B↓, 1,   FOXM1↓, 1,   FOXO3↑, 1,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 1,   miR-106b↓, 1,   miR-21↓, 1,   miR-34a↓, 2,   miR-34a↑, 1,   other↑, 1,   other↝, 2,   tumCV↓, 12,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 4,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↑, 2,   CTSB↓, 1,   CTSD↓, 1,   LC3II↑, 3,   MitoP↑, 1,   p62↓, 1,   PARK2↑, 1,   TumAuto↓, 1,   TumAuto↑, 7,  

DNA Damage & Repair(tgid=10) ⓘ

BRCA1↓, 2,   BRCA2↓, 1,   DNAdam↑, 11,   hTERT/TERT↓, 1,   P53↓, 2,   P53↑, 9,   P53↝, 1,   p‑P53↑, 2,   PARP↑, 3,   cl‑PARP↑, 6,   PCNA↓, 4,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 4,   CDK2↓, 5,   CDK4↓, 6,   CDK6↓, 2,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 4,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 10,   cycE/CCNE↓, 3,   GADD45A↓, 1,   Ki-67↓, 5,   mitA↑, 1,   P21↑, 5,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 1,   pRB↓, 1,   TumCCA?, 1,   TumCCA↑, 34,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

cFos↓, 1,   CSCs?, 1,   CSCs↓, 5,   Diff↑, 1,   IGF-1↓, 4,   Ki-67↓, 5,   mTORC1↓, 1,   NOTCH↓, 3,   NOTCH1↓, 1,   NOTCH1↑, 1,   Shh↓, 1,   TumCG↓, 8,   TumCP↓, 25,   Wnt↓, 4,  

Migration(tgid=13) ⓘ

AP-1↓, 2,   BACH1↓, 1,   Ca+2↑, 2,   i-Ca+2↑, 1,   Cdc42↓, 1,   Cofilin↓, 1,   p‑Cofilin↑, 1,   E-cadherin↓, 3,   E-cadherin↑, 3,   EMT↓, 9,   EMT↝, 1,   F-actin↓, 1,   FAK↓, 1,   p‑FAK↓, 1,   LAMs↓, 1,   LIMK2↓, 1,   MMP1↓, 1,   MMP2↓, 17,   MMP9↓, 14,   MMP9↑, 1,   MMPs↓, 5,   N-cadherin↓, 3,   pax↓, 1,   PDGF↓, 1,   Rac1↓, 1,   Rho↓, 1,   Rho↝, 1,   ROCK1↓, 1,   Slug?, 1,   Slug↓, 1,   Snail?, 1,   TET1↑, 1,   TGF-β↓, 1,   TIMP1↑, 5,   TIMP2↓, 1,   TIMP2↑, 2,   TRIB3↑, 1,   TumCI↓, 11,   TumCMig↓, 15,   TumMeta↓, 12,   TumMeta↑, 3,   β-catenin/ZEB1↓, 7,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 17,   angioG↑, 1,   CD31/PECAM-1↓, 2,   HIF-1↓, 2,   Hif1a↓, 7,   VEGF↓, 10,   VEGFR2/KDR/Flk1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB∅, 1,   EPR↑, 1,   GLUT1↓, 1,   MMP↓, 17,   TRPM7↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

p‑cDC2↓, 1,   COX2/PTGS2↓, 6,   COX2/PTGS2↑, 1,   CXCR4↓, 2,   FOXP3↑, 1,   HMGB1↓, 1,   IL10↓, 1,   IL10↑, 1,   IL17↓, 1,   IL1β↓, 2,   IL1β↑, 1,   IL6↓, 4,   IL8↓, 1,   Imm↑, 5,   Imm↝, 1,   Inflam↓, 9,   Inflam↝, 1,   MCT1↓, 1,   MyD88↑, 1,   NF-kB↓, 16,   NF-kB↑, 1,   NK cell↑, 2,   p65↓, 1,   PD-1↓, 1,   PD-L1↓, 1,   PGE2↓, 1,   PSA↓, 1,   RANTES↓, 1,   SOCS-3↓, 1,   TLR4↑, 1,   TNF-α↓, 3,   TNF-α↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   ERα/ESR1↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 7,   BioAv↑, 8,   BioAv↝, 4,   CBR1↓, 1,   ChemoSen↑, 30,   CompStab↓, 1,   CompStab↑, 1,   CYP1A1↑, 1,   CYP3A4↓, 1,   DDS↑, 1,   Dose?, 1,   Dose↝, 8,   eff↓, 2,   eff↑, 16,   eff↝, 1,   GSTM1↑, 1,   Half-Life↓, 1,   Half-Life↑, 1,   MDR1↓, 1,   P-gp/ABCB1↓, 3,   P-gp/ABCB1⇅, 1,   RadioS↑, 6,   selectivity↑, 12,   Synergy↑, 17,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AR↓, 1,   AST↓, 1,   BRCA1↓, 2,   CIT↓, 1,   EGFR↓, 4,   ERα/ESR1↓, 1,   FOXM1↓, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 1,   IL6↓, 4,   LDH↓, 1,   PD-L1↓, 1,   PSA↓, 1,   TG/TAG↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 28,   AntiDiabetic↑, 5,   AntiTum↑, 11,   cardioP↑, 4,   chemoP↑, 8,   chemoPv↑, 7,   ChemoSideEff↓, 1,   fatigue↓, 1,   hepatoP↑, 4,   neuroP↑, 2,   NP/CIPN↓, 2,   Obesity↑, 1,   OS↑, 2,   Pain↓, 1,   QoL↑, 1,   radioP↑, 3,   RenoP↑, 1,   Risk↓, 11,   Risk↑, 1,   toxicity↓, 4,   toxicity↝, 1,   TumVol↓, 1,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 3,   Bacteria↓, 1,   GutMicro↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   Ingr?, 1,   Ingr↝, 6,  
Total Targets: 342

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 4,   antiOx↑, 76,   Catalase↑, 22,   Fenton↓, 1,   GPx↑, 18,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 24,   GSR↑, 2,   GSTs↑, 5,   H2O2↓, 1,   HDL↓, 1,   HDL↑, 7,   HDL∅, 1,   HO-1↓, 1,   HO-1↑, 11,   hyperG↝, 1,   Keap1↝, 1,   lipid-P↓, 18,   MDA↓, 22,   MDA↑, 1,   MPO↓, 4,   NADH↓, 1,   NQO1↑, 2,   NQO1↝, 1,   NRF2↑, 17,   RNS↓, 2,   ROS?, 1,   ROS↓, 63,   ROS↑, 1,   mt-ROS?, 1,   selenoP↑, 1,   SOD↑, 30,   SOD1↑, 2,   SOD2↑, 1,   TAC↑, 3,   Trx↑, 1,   TrxR1↑, 1,   uricA↓, 1,   VitC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,   IronCh↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

DRP1/DNM1L↓, 1,   Insulin↓, 2,   Insulin↑, 3,   MFN2↑, 1,   mtDam↓, 1,   OCR↑, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 3,   5LO↝, 1,   ALAT↓, 11,   AMPK↓, 1,   AMPK↑, 8,   ATP↓, 1,   ATP↑, 3,   CRM↑, 2,   DGAT1↓, 1,   FASN↓, 2,   FFA/NEFA↓, 2,   glucose↓, 15,   glucose↝, 1,   GlucoseCon↑, 1,   glyC↓, 1,   GSK‐3β↓, 6,   GSK‐3β↑, 1,   p‑GSK‐3β↑, 1,   HMG-CoA↓, 2,   LDL↓, 17,   lipidLev↓, 4,   NAD↓, 1,   PFK↓, 1,   PLA2↓, 2,   SIRT1↑, 1,   SIRT1↝, 1,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Apoptosis↓, 1,   BAX↓, 5,   Bcl-2↓, 1,   Bcl-2↑, 1,   Casp↓, 1,   Casp12↓, 1,   Casp3↓, 5,   Casp3↑, 1,   cl‑Casp3↓, 1,   cl‑Casp8↓, 1,   Casp9↓, 1,   Cyt‑c↓, 2,   Fas↓, 1,   Ferroptosis↓, 1,   iNOS↓, 3,   necrosis↓, 1,   Pyro↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   Akt↑, 4,   Akt2↓, 1,   CREB↑, 1,   ERK↓, 1,   IKKα↓, 1,   IκB↓, 1,   JAK↓, 1,   JAK2↓, 1,   JNK↓, 1,   MAPK↓, 4,   mTOR↓, 1,   mTOR↑, 1,   PI3K↓, 2,   PI3K↑, 4,   PP2A↑, 1,   PROKR1↑, 1,   PROKR2↑, 1,   PTP1B↓, 1,   RIP1↓, 1,   STAT↓, 1,   STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 6,   ATF2↑, 1,   ATF4↓, 2,   FOXO3↑, 1,   other?, 1,   other↓, 3,   other↑, 5,   other↝, 9,   RUNX2↑, 1,   SOX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   CHOP/DDIT3↓, 4,   ER Stress↓, 1,   GRP78/BiP↓, 2,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 2,   HSP90↓, 1,   NQO2↑, 1,   PERK↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 2,   Beclin-1/ATG6↑, 1,   LC3II↓, 1,   LC3II↑, 1,   MitoP↑, 1,   p62↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 5,   P53↓, 1,   PARP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

GADD34↓, 1,   Ki-67↑, 1,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   GH↑, 1,   HH↓, 1,   Ki-67↑, 1,   Nestin↑, 1,   neuroG↑, 1,   NOTCH1↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 10,   AP-1↓, 1,   Ca+2↓, 1,   COL1↑, 1,   MLC2/MYL9↝, 1,   MMP9↓, 3,   PROK2↑, 1,   TGF-β↓, 1,   TIMP1↓, 1,   Tyro3↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Endoglin↑, 1,   p‑eNOS↑, 1,   Hif1a↓, 2,   NO↓, 5,   NO↑, 1,   TXA2↓, 1,   VCAM-1↓, 3,   VEGF↓, 3,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 2,   GastroP↑, 5,   GLUT4↑, 1,   H+/K+-ATPase↓, 1,   MMP↑, 3,   OCLN↓, 1,   OCLN↝, 1,   TJ↑, 1,   TRPC1↓, 1,   TRPM7↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 3,   COX2/PTGS2↓, 12,   COX2/PTGS2↑, 1,   ICAM-1↓, 2,   IFN-γ↓, 3,   IL10↓, 5,   IL10↑, 2,   IL12↓, 1,   IL17↓, 2,   IL18↓, 1,   IL1β↓, 9,   IL23↓, 1,   IL4↓, 1,   IL5↓, 1,   IL6↓, 19,   IL8↓, 3,   Imm↓, 1,   Imm↑, 23,   Imm↝, 1,   Inflam↓, 85,   Inflam↑, 2,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 2,   MyD88↓, 1,   NF-kB↓, 23,   NLRP3↓, 5,   PGE2↓, 7,   PGE2↑, 1,   TLR4↓, 4,   TNF-α↓, 22,  

Cellular Microenvironment(tgid=17) ⓘ

GGT/CD224↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 14,   BChE↓, 6,   BDNF↓, 1,   BDNF↑, 5,   GABA↑, 1,   MAOA↓, 2,   MAOB↓, 2,   NGF↑, 3,   PSD95↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 9,   Aβ↓, 7,   BACE/β-secretase↓, 3,   tau↓, 3,   p‑tau↓, 1,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   CYP19↓, 1,   END↑, 1,   Estro↓, 1,   PPARα↝, 1,   PPARγ↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 20,   BioAv↑, 26,   BioAv⇅, 2,   BioAv↝, 13,   CompStab↓, 1,   CompStab↝, 2,   CYP2E1↓, 2,   Dose?, 2,   Dose↑, 3,   Dose↝, 14,   eff↓, 1,   eff↑, 9,   eff↝, 1,   GSTA1↑, 1,   Half-Life↓, 2,   Half-Life↑, 1,   Half-Life↝, 4,   P450↓, 1,   Synergy↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 11,   ALP↓, 2,   AST↓, 12,   BG↓, 1,   BloodF↑, 1,   BMD↑, 1,   BP↓, 14,   BUN↓, 1,   creat↓, 1,   CRP↓, 6,   HOMA↓, 1,   hs-CRP↓, 3,   IL6↓, 19,   IRes↓, 1,   IRes↑, 1,   IRes↝, 1,   LDH↓, 4,   LDH↑, 1,   NOS2↓, 1,   TC↓, 2,   TG/TAG↓, 4,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 2,   AntiAge↑, 6,   antiAll↑, 11,   AntiArt↑, 9,   AntiCan↑, 32,   antiCG↑, 1,   AntiDiabetic↓, 4,   AntiDiabetic↑, 128,   antiM↑, 1,   antiNeop↑, 1,   antiPs↑, 2,   antiPy↑, 1,   AntiTum↓, 1,   AntiTum↑, 6,   Bone Healing↑, 1,   cardioP↑, 52,   chemoP↑, 5,   chemoPv↑, 5,   cognitive↑, 15,   cough?, 1,   diuretic↑, 4,   fatigue↓, 2,   hepatoP↑, 47,   Learn↑, 1,   memory↑, 14,   motorD↑, 1,   Mucositis↓, 1,   neuroP?, 2,   neuroP↓, 1,   neuroP↑, 59,   Obesity↓, 27,   OS↑, 2,   Pain↓, 2,   QoL↑, 2,   radioP↑, 1,   RenoP↑, 11,   Sleep↑, 2,   SoreThr?, 1,   Strength↑, 1,   Stroke↓, 9,   toxicity?, 1,   toxicity↓, 18,   toxicity↑, 1,   toxicity⇅, 1,   toxicity↝, 8,   toxicity∅, 2,   Weight↓, 2,   Wound Healing↑, 14,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 18,   AntiFungal↓, 1,   AntiFungal↑, 11,   AntiP↑, 2,   AntiViral↑, 14,   Bacteria↓, 39,   Bacteria↑, 1,   Diar↓, 1,   GutMicro↑, 24,   Sepsis↓, 2,  

Ingredients & Constituents(tgid=25) ⓘ

CA↑, 1,   Catechins↑, 1,   FA↑, 1,   GA↑, 1,   Ingr?, 2,   Ingr↑, 4,   Ingr↝, 18,   Phen↑, 1,   QC↑, 1,  
Total Targets: 352

Scientific Paper Hit Count for: AntiDiabetic, AntiDiabetic
8 Chlorogenic acid
5 Kaempferol
4 Dandelion Root
4 Emodin
4 Flaxseed/Linseed
3 Astaxanthin
3 Carvacrol
3 Centella asiatica / Gotu kola → asiaticoside
3 Cinnamon
3 diet Fermented Foods
3 Isoliquiritigenin
3 isoquercitrin
3 Isovitexin
3 SDG/lignans
3 Metformin
2 Silver-NanoParticles
2 Allicin (mainly Garlic)
2 Biochanin A
2 Rutin
2 Carica papaya leaf extract
2 D-limonene
2 Eugenol
2 Fisetin
2 flavonoids
2 Formononetin
2 Genistein (soy isoflavone)
2 Hibiscus sabdariffa
2 Vitexin
2 Lemongrass Extract/Citral
2 Moringa oleifera
2 Mucuna pruriens/Velvet Bean
2 Nimbolide
2 Purple Corn / Purple Maize
2 Quercetin
2 Selenium NanoParticles
2 Ursolic acid
1 Astragalus
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Anethole/trans-Anethole
1 Aloe anthraquinones
1 Bacopa monnieri
1 Boswellia (frankincense)
1 Black Rice, Oryza sativa
1 buckwheat sprouts
1 Capsaicin
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Celastrol
1 Chocolate
1 Chrysin
1 Hydroxycinnamic-acid
1 Crocetin
1 Carvone
1 Cucurbitacin
1 Date Fruit Extract
1 diet Short Term Fasting
1 Ferulic acid
1 Fennel Oil/Foeniculum vulgare
1 Fucoidan
1 Gallic acid
1 Gamma-aminobutyric acid
1 Geraniol
1 Graviola
1 Hydrogen Gas
1 High-Ozonide Oil
1 Inositol
1 Ivermectin
1 Licorice
1 Luteolin
1 Lycopene
1 Magnolol
1 Matrine
1 Moringin
1 Mushroom Chaga, Inonotus obliquus
1 Mushroom Lion’s Mane, Hericium erinaceus
1 Neem
1 Marjoram (Origanum majorana)
1 Psoralidin
1 Curcumin
1 Thymol-Thymus vulgaris
1 Walnut
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1385  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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