| Source: HalifaxProj(inhibit) |
| Type: |
| Interleukin-6 (IL-6) is a cytokine that plays a significant role in inflammation and the immune response. It is produced by various cell types, including T cells, B cells, macrophages, and fibroblasts. IL-6 can promote tumor cell proliferation and survival. Many cancer cells produce IL-6, which can create an autocrine loop that supports their growth. IL-6 is a high-value inflammatory biomarker in cancer, reporting cytokine burden, catabolic stress, and STAT3-linked survival signaling. While not tumor-specific, elevated and rising IL-6 strongly predicts poor prognosis and limited treatment tolerance, making it an important system-state indicator alongside CRP and ferritin. |
| 3708- | dietSTF, | Fasting as a Therapy in Neurological Disease |
| 1607- | EA, | Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions |
| - | Review, | GC, | NA |
| 1620- | EA, | Rad, | Radiosensitizing effect of ellagic acid on growth of Hepatocellular carcinoma cells: an in vitro study |
| - | in-vitro, | Liver, | HepG2 |
| 27- | EA, | Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice |
| - | in-vivo, | PC, | PANC1 |
| - | in-vitro, | GBM, | U87MG |
| 1503- | EGCG, | Epigenetic targets of bioactive dietary components for cancer prevention and therapy |
| - | Review, | NA, | NA |
| 3227- | EGCG, | Epigallocatechin-3-gallate treatment to promote neuroprotection and functional recovery after nervous system injury |
| - | NA, | Nor, | NA |
| 3225- | EGCG, | Epigallocatechin‐3‐Gallate Ameliorates Diabetic Kidney Disease by Inhibiting the TXNIP/NLRP3/IL‐1β Signaling Pathway |
| - | in-vitro, | Nor, | NA | - | in-vivo, | Nor, | NA |
| 3233- | EGCG, | Epigallocatechin gallate inhibits HeLa cells by modulation of epigenetics and signaling pathways |
| - | in-vitro, | Cerv, | HeLa |
| 3201- | EGCG, | Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential |
| - | Review, | NA, | NA |
| 3594- | EGCG, | Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cells |
| - | in-vitro, | AD, | HMC1 |
| 5487- | EP, | High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas |
| - | in-vivo, | GBM, | NA |
| 5055- | Ex, | Why exercise has a crucial role in cancer prevention, risk reduction and improved outcomes |
| - | Review, | Var, | NA |
| 3714- | FA, | Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review |
| - | Review, | AD, | NA |
| 2861- | FIS, | The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress |
| - | Review, | Nor, | NA | - | Review, | Stroke, | NA | - | Review, | Park, | NA |
| 2841- | FIS, | Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver Cancer |
| - | in-vitro, | Nor, | RAW264.7 | - | in-vitro, | Liver, | HepG2 | - | in-vitro, | Liver, | Hep3B | - | in-vitro, | Liver, | HUH7 |
| 2843- | FIS, | Fisetin and Quercetin: Promising Flavonoids with Chemopreventive Potential |
| - | Review, | Var, | NA |
| 805- | GAR, | Cisplatin, | PacT, | Garcinol Exhibits Anti-Neoplastic Effects by Targeting Diverse Oncogenic Factors in Tumor Cells |
| - | Review, | NA, | NA |
| 4003- | Gins, | Neuroprotective Potentials of Panax Ginseng Against Alzheimer's Disease: A Review of Preclinical and Clinical Evidences |
| - | Review, | adrenal, | NA |
| 4511- | GLA, | Gamma-Linolenic Acid (GLA) Protects against Ionizing Radiation-Induced Damage: An In Vitro and In Vivo Study |
| - | vitro+vivo, | Nor, | RAW264.7 |
| 4346- | H2, | Medical Application of Hydrogen in Hematological Diseases |
| - | Review, | NA, | NA |
| 4307- | H2, | Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models |
| - | in-vivo, | AD, | NA |
| 2521- | H2, | Oxyhydrogen Gas: A Promising Therapeutic Approach for Lung, Breast and Colorectal Cancer |
| - | Review, | CRC, | NA | - | Review, | Lung, | NA | - | Review, | BC, | NA |
| 2516- | H2, | Hydrogen Gas in Cancer Treatment |
| - | Review, | Var, | NA |
| 2514- | H2, | Hydrogen: A Novel Option in Human Disease Treatment |
| - | Review, | NA, | NA |
| 2503- | H2, | Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report |
| - | Case Report, | Lung, | NA |
| 2530- | H2, | Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases |
| - | Case Report, | PSA, | NA |
| 3768- | H2, | Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial |
| - | Trial, | AD, | NA |
| 3770- | H2, | Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 3772- | H2, | Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis |
| - | in-vivo, | AD, | NA |
| 3773- | H2, | Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases |
| - | Review, | Park, | NA |
| 3787- | H2, | Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis |
| - | Review, | AD, | NA |
| 3766- | H2, | The role of hydrogen in Alzheimer′s disease |
| - | Review, | AD, | NA |
| 1637- | HCA, | OLST, | Orlistat and Hydroxycitrate Ameliorate Colon Cancer in Rats: The Impact of Inflammatory Mediators |
| - | in-vivo, | Colon, | NA |
| 2871- | HNK, | Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling |
| - | in-vivo, | Nor, | NA |
| 2868- | HNK, | Honokiol: A review of its pharmacological potential and therapeutic insights |
| - | Review, | Var, | NA | - | Review, | Sepsis, | NA |
| 2885- | HNK, | Honokiol: a novel natural agent for cancer prevention and therapy |
| 5119- | JG, | Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice |
| - | in-vivo, | Nor, | NA |
| 4007- | K+, | The increased potassium intake improves cognitive performance and attenuates histopathological markers in a model of Alzheimer's disease |
| - | in-vivo, | AD, | NA |
| 4292- | LT, | Luteolin for neurodegenerative diseases: a review |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | MS, | NA | - | Review, | Stroke, | NA |
| 2921- | LT, | Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies |
| - | Review, | Nor, | NA |
| 2911- | LT, | Luteolin targets MKK4 to attenuate particulate matter-induced MMP-1 and inflammation in human keratinocytes |
| - | in-vitro, | Nor, | HaCaT |
| 2919- | LT, | Luteolin as a potential therapeutic candidate for lung cancer: Emerging preclinical evidence |
| - | Review, | Var, | NA |
| 2916- | LT, | Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies |
| - | Review, | Var, | NA | - | Review, | AD, | NA | - | Review, | Park, | NA |
| 3531- | Lyco, | Lycopene attenuates the inflammation and apoptosis in aristolochic acid nephropathy by targeting the Nrf2 antioxidant system |
| - | in-vivo, | Nor, | NA |
| 3528- | Lyco, | The Importance of Antioxidant Activity for the Health-Promoting Effect of Lycopene |
| - | Review, | Nor, | NA | - | Review, | AD, | NA | - | Review, | Park, | NA |
| 3264- | Lyco, | Pharmacological potentials of lycopene against aging and aging‐related disorders: A review |
| - | Review, | Var, | NA | - | Review, | AD, | NA | - | Review, | Stroke, | NA |
| 3277- | Lyco, | Recent trends and advances in the epidemiology, synergism, and delivery system of lycopene as an anti-cancer agent |
| - | Review, | Var, | NA |
| 3278- | Lyco, | Anti-inflammatory effect of lycopene in SW480 human colorectal cancer cells |
| - | in-vitro, | Colon, | SW480 |
| 1708- | Lyco, | The Anti-Cancer Activity of Lycopene: A Systematic Review of Human and Animal Studies |
| - | Review, | Var, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:158 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid