| Source: HalifaxProj(block) |
| Type: |
| An enzyme that produces nitric oxide (NO) in response to inflammatory stimuli. iNOS can promote tumor growth by enhancing blood flow and nutrient supply to tumors through vasodilation. It may also help cancer cells evade apoptosis (programmed cell death). Immune Activation: In some contexts, NO produced by iNOS can enhance the immune response against tumors, promoting the activation of immune cells that can target and destroy cancer cells. Inhibition of Tumor Growth: High levels of NO can induce cytotoxic effects on tumor cells, leading to reduced proliferation and increased apoptosis. |
| 3320- | SIL, | Neuroprotective Potential of Silymarin against CNS Disorders: Insight into the Pathways and Molecular Mechanisms of Action |
| - | Review, | AD, | NA |
| 3319- | SIL, | Silymarin and neurodegenerative diseases: Therapeutic potential and basic molecular mechanisms |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | Stroke, | NA |
| 3314- | SIL, | Silymarin: Unveiling its pharmacological spectrum and therapeutic potential in liver diseases—A comprehensive narrative review |
| - | Review, | NA, | NA |
| 3309- | SIL, | Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives |
| - | Review, | NA, | NA |
| 3310- | SIL, | Silymarin attenuates paraquat-induced lung injury via Nrf2-mediated pathway in vivo and in vitro |
| - | in-vitro, | Lung, | A549 |
| 3290- | SIL, | A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents |
| - | Analysis, | Var, | NA |
| 2220- | SK, | Shikonin Alleviates Gentamicin-Induced Renal Injury in Rats by Targeting Renal Endocytosis, SIRT1/Nrf2/HO-1, TLR-4/NF-κB/MAPK, and PI3K/Akt Cascades |
| - | in-vivo, | Nor, | NA |
| 2213- | SK, | Shikonin attenuates cerebral ischemia/reperfusion injury via inhibiting NOD2/RIP2/NF-κB-mediated microglia polarization and neuroinflammation |
| - | in-vivo, | Stroke, | NA |
| 3960- | Taur, | Versatile Triad Alliance: Bile Acid, Taurine and Microbiota |
| - | Review, | AD, | NA | - | Review, | Stroke, | NA |
| 5339- | TFdiG, | Pre-treated theaflavin-3,3′-digallate has a higher inhibitory effect on the HCT116 cell line |
| - | in-vitro, | CRC, | HCT116 |
| 5336- | TFdiG, | Theaflavin-3,3′-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways |
| - | in-vivo, | Nor, | NA |
| 4173- | TQ, | Thymoquinone Can Improve Neuronal Survival and Promote Neurogenesis in Rat Hippocampal Neurons |
| - | in-vivo, | NA, | NA |
| 3404- | TQ, | The Neuroprotective Effects of Thymoquinone: A Review |
| - | Review, | Var, | NA | - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | Stroke, | NA |
| 3427- | TQ, | Chemopreventive and Anticancer Effects of Thymoquinone: Cellular and Molecular Targets |
| 3429- | TQ, | Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells |
| - | in-vitro, | AML, | NA | - | in-vivo, | NA, | NA |
| 3559- | TQ, | Molecular signaling pathway targeted therapeutic potential of thymoquinone in Alzheimer’s disease |
| - | Review, | AD, | NA | - | Review, | Var, | NA |
| 3571- | TQ, | The Role of Thymoquinone in Inflammatory Response in Chronic Diseases |
| - | Review, | Var, | NA | - | Review, | Stroke, | NA |
| 2092- | TQ, | Dissecting the Potential Roles of Nigella sativa and Its Constituent Thymoquinone on the Prevention and on the Progression of Alzheimer's Disease |
| - | Review, | AD, | NA |
| 5022- | UA, | Ursolic Acid’s Alluring Journey: One Triterpenoid vs. Cancer Hallmarks |
| - | Review, | Var, | NA |
| 634- | VitC, | Intravenous ascorbic acid to prevent and treat cancer-associated sepsis? |
| - | Analysis, | NA, | NA |
| 2276- | VitK2, | Vitamin K2 (MK-7) Intercepts Keap-1/Nrf-2/HO-1 Pathway and Hinders Inflammatory/Apoptotic Signaling and Liver Aging in Naturally Aging Rat |
| - | in-vivo, | Nor, | NA |
| 2277- | VitK2, | Vitamin K2 suppresses rotenone-induced microglial activation in vitro |
| - | in-vitro, | Nor, | BV2 | - | NA, | AD, | NA | - | NA, | Park, | NA |
| - | in-vitro, | Nor, | RAW264.7 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:159 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid