TumCG Cancer Research Results

TumCG, Tumor cell growth: Click to Expand ⟱
Source:
Type:
Normal cells grow and divide in a regulated manner through the cell cycle, which consists of phases (G1, S, G2, and M).
Cancer cells often bypass these regulatory mechanisms, leading to uncontrolled proliferation. This can result from mutations in genes that control the cell cycle, such as oncogenes (which promote cell division) and tumor suppressor genes (which inhibit cell division).
Scientific Papers found: Click to Expand⟱
5543- BBM,    Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo
- in-vivo, Lung, B16-F10 - vitro+vivo, Lung, A549 - in-vitro, BC, MDA-MB-231
BioAv↓, Half-Life↓, eff↑, TumMeta↓, TumCP↓, TumCG↓, Apoptosis↑, TumCCA↑, MMP2↓, MMP9↓, VEGF↓, Bcl-2↓, eff↑, EPR↑,
5555- BBM,    Berbamine inhibits cell proliferation and invasion by increasing FTO expression in renal cell carcinoma cells
- vitro+vivo, RCC, NA
TumCP↓, TumCMig↓, TumCI↓, TumCG↓, toxicity↓, FTO↑,
5549- BBM,    Synergistic Anticancer Effect of a Combination of Berbamine and Arcyriaflavin A against Glioblastoma Stem-like Cells
- in-vitro, GBM, NA
eff?, tumCV↓, TumCG↓, ROS↑, P53↑, CSCs↓, CD133↓, ALDH1A1↓, Nanog↓, SOX2↓, OCT4↓, CDK1↓, CaMKII ↓, STAT3↓, Akt↓, ERK↓,
1397- BBR,  Chemo,    Effects of Coptis extract combined with chemotherapeutic agents on ROS production, multidrug resistance, and cell growth in A549 human lung cancer cells
- in-vitro, Lung, A549
TumCG↓, ROS↑, MDR1↓,
1392- BBR,    Based on network pharmacology and experimental validation, berberine can inhibit the progression of gastric cancer by modulating oxidative stress
- in-vitro, GC, AGS - in-vitro, GC, MKN45
TumCG↓, TumCMig↓, ROS↑, MDA↑, SOD↓, NRF2↓, HO-1↓, Hif1a↓, EMT↓, Snail↓, Vim↓,
1387- BBR,    Antitumor Activity of Berberine by Activating Autophagy and Apoptosis in CAL-62 and BHT-101 Anaplastic Thyroid Carcinoma Cell Lines
- in-vitro, Thyroid, CAL-62
TumCG↓, Apoptosis↑, LC3B↑, ROS↑, PI3K↓, Akt↓, mTOR↓,
1375- BBR,    13-[CH2CO-Cys-(Bzl)-OBzl]-Berberine: Exploring The Correlation Of Anti-Tumor Efficacy With ROS And Apoptosis Protein
- in-vitro, CRC, HCT8 - in-vivo, NA, NA
ROS↑, TumCP↓, XIAP↓, TumCG↓, *toxicity↓,
2335- BBR,    Chemoproteomics reveals berberine directly binds to PKM2 to inhibit the progression of colorectal cancer
- in-vitro, CRC, HT29 - in-vitro, CRC, HCT116 - in-vivo, NA, NA
PKM2↓, Glycolysis↓, p‑STAT3↓, Bcl-2↓, cycD1/CCND1↓, TumCG↓, Ki-67↓, lactateProd↓, glucose↓,
2692- BBR,    Berberine affects osteosarcoma via downregulating the caspase-1/IL-1β signaling axis
- in-vitro, OS, MG63 - in-vitro, OS, SaOS2 - in-vivo, NA, NA
Casp1↓, IL1β↓, TumCG↓, Dose↝, Apoptosis↑, Inflam↓,
2702- BBR,    The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1
- in-vitro, Lung, A549 - in-vitro, Lung, H1975
TumCG↓, MAPK↓, FOXO3↑, TumCCA↑, TumCMig↓, TumCI↓, Sp1/3/4↓, PDK1↓, DNMT1↓, eff↑,
2708- BBR,    Berberine decelerates glucose metabolism via suppression of mTOR‑dependent HIF‑1α protein synthesis in colon cancer cells
- in-vitro, CRC, HCT116
TumCG↓, GlucoseCon↓, GLUT1↓, LDHA↓, HK2↓, Hif1a↓, mTOR↓, Glycolysis↓,
2712- BBR,    Suppression of colon cancer growth by berberine mediated by the intestinal microbiota and the suppression of DNA methyltransferases (DNMTs)
- in-vitro, Colon, HT29 - in-vivo, NA, NA
TumCG↓, GutMicro↑, other↝, IL10↓, cMyc↓, DNMT1↓, DNMTs↓,
1030- BBR,    Berberine diminishes cancer cell PD-L1 expression and facilitates antitumor immunity via inhibiting the deubiquitination activity of CSN5
- in-vitro, Lung, H460
PD-L1↓, TumCG↓, Ki-67↓, cl‑Casp3↑,
1010- BBR,    Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells
- vitro+vivo, CRC, NA
β-catenin/ZEB1↓, TumCG↓,
7- BBR,    Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth
- vitro+vivo, MB, LS174T
HH↓, Gli1∅, PTCH1↓, Smo↓, TumCG↓,
5548- BBR,    Berbamine induces SMMC-7721 cell apoptosis via upregulating p53, downregulating survivin expression and activating mitochondria signaling pathway
- in-vitro, HCC, SMMC-7721 cell
TumCG↓, Apoptosis↑, Cyt‑c↑, BAX↑, P53↑, Bcl-2↓, survivin↓,
5177- BBR,    Berberine induces apoptosis in human HSC-3 oral cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway
- in-vitro, Oral, HMC3
TumCCA↑, Apoptosis↑, TumCG↓, Casp3↑, TumCCA↑, ROS↑, Ca+2↑, MMP↓, ER Stress↑, Cyt‑c↑,
1031- BCA,    Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer
- vitro+vivo, CRC, HCT116 - vitro+vivo, CRC, SW-620
PD-L1↓, TumCG↓, Zeb1↓, E-cadherin↑, N-cadherin↓, EMT↓,
5636- BCA,    Biochanin A Induces S Phase Arrest and Apoptosis in Lung Cancer Cells
- vitro+vivo, Lung, A549
tumCV↓, TumCCA↑, Apoptosis↑, MMP↓, TumCG↓, P21↑, Casp3↑, Bcl-2↑,
6518- BCP,    beta-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models
- vitro+vivo, CRC, HCT116
angioG↓, VEGF↓, TumVol↓, HSPD1 / HSP60↓, HTRA↓, survivin↓, XIAP↓, P21↑, TumCP↓, TumCMig↓, TumCG↓, Dose↝,
6513- BCP,    β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through down-modulation of NF-κB-regulated gene products
Apoptosis↑, TumCG↓, TumMeta↓, STAT3↓, PI3K↓, Akt↓, mTOR↓, ChemoSen↑, IAP1↓, IAP2↓, Bcl-2↓, Bcl-xL↓, survivin↓, COX2↓, cycD1/CCND1↓, cMyc↓, TumCI↓, MMP9↓, ICAM-1↓, angioG↓, VEGF↓, NF-kB↓,
6496- BCP,    β-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models
- vitro+vivo, CRC, HCT116 - in-vitro, Nor, HUVECs
angioG↓, VEGF↓, TumVol↓, Apoptosis↑, HSPD1 / HSP60↓, HTRA↓, survivin↓, XIAP↓, P21↑, *toxicity↓, *neuroP↑, *ROS↓, *COX2↓, *Inflam↓, *cardioP↑, AntiCan↑, ChemoSen↑, ROS↑, MMP↑, Bax:Bcl2↑, TumCG↓,
6497- BCP,  Cisplatin,    Beta-Caryophyllene Enhances the Anti-Tumor Activity of Cisplatin in Lung Cancer Cell Lines through Regulating Cell Cycle and Apoptosis Signaling Molecules
- in-vitro, Lung, NA
TumCG↓, TumCP↓, Apoptosis↑, toxicity↓, ChemoSen↑, P21↑, Bcl-xL↑, Bcl-2↓, EMT↓, E-cadherin↑, eff↑, MMP↓,
6501- BCP,    β-Caryophyllene promotes oxidative stress and apoptosis in KB cells through activation of mitochondrial-mediated pathway - An in-vitro and in-silico study
- in-vitro, Oral, KB
TumCG↓, Apoptosis↑, TumMeta↓, NF-kB↓, PI3K↓, Akt↓, ROS↑, MMP↓, DNAdam↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, PCNA↓, cycD1/CCND1↓, TNF-α↓, COX2↓, iNOS↓, IL6↓, VEGF↓,
5582- BetA,    Targeting mitochondrial apoptosis by betulinic acid in human cancers
- Review, Var, NA
Apoptosis↑, MMP↓, Cyt‑c↑, ROS↑, NF-kB↑, angioG↓, mtDam↑, TOP1↓, selectivity↑, ChemoSen↑, TumCG↓, chemoPv↑, RadioS↑,
5587- BetA,  Rad,    Effects of betulinic acid alone and in combination with irradiation in human melanoma cells
- in-vitro, Melanoma, NA
TumCG↓, RadioS↑, Apoptosis↑, selectivity↑,
2741- BetA,    Betulinic acid triggers apoptosis and inhibits migration and invasion of gastric cancer cells by impairing EMT progress
- in-vitro, GC, SNU16 - in-vitro, GC, NCI-N87 - in-vivo, NA, NA
TumCG↓, TumCMig↓, TumCI↓, N-cadherin↓, E-cadherin↑, EMT↓, Ki-67↓, MMP2↓,
2745- BetA,    Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors
- in-vitro, CRC, RKO - in-vitro, CRC, SW480 - in-vivo, NA, NA
Apoptosis↑, TumCG↓, Sp1/3/4↓, survivin↓, VEGF↓, p65↓, EGFR↓, cycD1/CCND1↓, ROS↑, MMP↓,
2746- BetA,    Betulinic acid induces apoptosis and inhibits metastasis of human colorectal cancer cells in vitro and in vivo
- in-vitro, CRC, HCT116 - in-vivo, CRC, NA
TumCG↓, BAX↑, Bcl-2↓, ROS↑, MMP↓, TIMP2↑, TumVol↓,
2756- BetA,    Betulinic acid inhibits growth of hepatoma cells through activating the NCOA4-mediated ferritinophagy pathway
- in-vitro, HCC, HUH7 - in-vitro, HCC, H1299
TumCP↓, ROS↑, antiOx↓, TumCG↓, TumCMig↓, NRF2↓, GPx4↓, HO-1↓, NCOA4↑, FTH1↓, Ferritin↑, Ferroptosis↑, GSH↓, MDA↓,
5729- BF,    Bufalin: a potential drug for regulating EGFR-TKIs resistance in lung cancer via the EGFR-PI3K/Akt-mTOR signaling
- in-vitro, Lung, NA
TumCCA↑, Apoptosis↑, TumCG↓, EGFR↓, PI3K↓, Akt↓, mTOR↓, P70S6K↓,
5725- BF,  TMZ,    Bufalin Induces Apoptosis and Improves the Sensitivity of Human Glioma Stem-Like Cells to Temozolamide
- in-vitro, GBM, NA
TumCG↓, TumCP↓, CSCs↓, cl‑Casp3↑, PARP↑, Telomerase↓, eff↑,
5726- BF,    Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain
- Review, neuroblastoma, SK-N-BE
Apoptosis↑, TumCP↓, TumCMig↓, MMP↓, ROS↑, ETC↓, Bcl-2↓, BAX↑, cl‑Casp3↑, cl‑PARP↑, eff↓, TumCG↓, Ki-67↓, PCNA↓,
1250- Bif,    Oral administration of Bifidobacterium breve promotes antitumor efficacy via dendritic cells-derived interleukin 12
- in-vitro, SCC, NA
TumCG↓, Apoptosis↑, CCL20↑, IL12↑,
5621- Bif,  immuno,    Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
TumCG↓, GutMicro↑,
5688- BJ,    Brucea Javanica Oil Emulsion Injection inhibits proliferation of pancreatic cancer via regulating apoptosis-related genes
- vitro+vivo, PC, MIA PaCa-2
TumCG↓, TumCI↓, TumCCA↑, Apoptosis↑, BAX↑, cl‑Casp3↑, Bcl-2↓, MMP2↓, BACE↓, TOP2↓,
5687- BJ,    Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways
- vitro+vivo, AML, U937
Apoptosis↑, Casp8↑, TumCCA↑, cl‑PARP↑, eff↝, TumCG↓, necrosis↑, Fas↑, TumCCA↑, selectivity↑,
5689- BJ,    Brucea javanica oil inhibited the proliferation, migration, and invasion of oral squamous carcinoma by regulated the MTFR2 pathway
- vitro+vivo, Oral, CAL27
TumCP↓, TumCMig↓, TumCI↓, SOD2↓, H2O2↓, OXPHOS↑, Glycolysis↓, ROS↑, RadioS↑, Hif1a↓, TumCG↓,
5690- BJ,  BRU,    Brusatol: A potential sensitizing agent for cancer therapy from Brucea javanica
- Review, Var, NA
NRF2↓, TumCG↓, ChemoSen↑, ROS↑, NF-kB↓, Akt↓, mTOR↓, TumCCA↑, Apoptosis↑, PARP↑, Casp↑, P53↓, Bcl-2↓, PI3K↓, JAK2↓, EMT↓, p27↑, ROCK1↓, MMP2↓, MMP9↓, NRF2↓, AntiTum↑, HO-1↓, NQO1↓, VEGF↓, MRP1/ABCC1↓, RadioS↑, PhotoS↑, toxicity↝,
5475- BM,    The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis
- in-vitro, Colon, HT29 - in-vitro, Colon, SW48 - in-vitro, Colon, SW-620 - in-vitro, CRC, HCT116
AQPs↓, TumCG↓, TumCCA↓, Apoptosis↑, eff↝,
5678- BML,    Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy
- in-vivo, CRC, NA
AntiCan↑, TumCG↓, ROS↑, Apoptosis↑, Endoglin↑, Casp3↑, Casp8↑, Casp9↑, ATG5↑, Beclin-1↑, p62↑, PARP↑,
5685- BML,    The Therapeutic Effects of Bromelain against Colorectal Cancer: A Systematic Review
- Review, CRC, NA
TumCG↓, TumMeta↓, ROS⇅, Bcl-2↓, Casp3↑, Casp7↑, Casp8↑, Casp9↑, P53↑,
739- Bor,    Borax regulates iron chaperone- and autophagy-mediated ferroptosis pathway in glioblastoma cells
- in-vitro, GBM, U87MG - in-vitro, Nor, HMC3
TumCG↓, TumCP↓, TumCCA↑, PCBP1↓, GSH↓, GPx4↓, Beclin-1↑, MDA↑, ACSL4↑, Casp3↑, Casp7↑, Ferroptosis↑, *toxicity↓,
747- Bor,    Growing Evidence for Human Health Benefits of Boron
- Review, NA, NA
TumCG↓, Risk↓,
755- Bor,    https://aacrjournals.org/cancerres/article/67/9_Supplement/4220/535557/Boric-acid-induces-apoptosis-in-both-prostate-and
- in-vitro, Pca, DU145 - in-vitro, PC, PC3
TumCG↓, Apoptosis↑,
762- Bor,    Mechanism of boric acid cytotoxicity in breast cancer cell lines
- in-vitro, BC, MCF7 - in-vitro, BC, ZR-75-1
TumCG↓,
716- Bor,    Sugar-borate esters--potential chemical agents in prostate cancer chemoprevention
TumCG↓, Apoptosis↑,
720- Bor,    High Concentrations of Boric Acid Trigger Concentration-Dependent Oxidative Stress, Apoptotic Pathways and Morphological Alterations in DU-145 Human Prostate Cancer Cell Line
- in-vitro, Pca, DU145
ROS↑, TumCG↓, Apoptosis↑,
729- Bor,    Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies
- in-vitro, GBM, U87MG - in-vivo, Nor, HaCaT
TOS↑, TumCG↓, MDA↑, SOD↑, Catalase↑, TAC↓, GSH↓, BRAF↑, MAPK↓, PTEN↓, Raf↓, *toxicity↓,
2775- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
ROS↑, ER Stress↑, TumCG↓, Apoptosis↑, Inflam↓, ChemoSen↑, Casp↑, ERK↓, cl‑PARP↑, AR↓, cycD1/CCND1↓, VEGFR2↓, CXCR4↓, radioP↑, NF-kB↓, VEGF↓, P21↑, Wnt↓, β-catenin/ZEB1↓, Cyt‑c↑, MMP2↓, MMP1↓, MMP9↓, PI3K↓, MAPK↓, JNK↑, *5LO↓, *NRF2↑, *HO-1↑, *MDA↓, *SOD↑, *hepatoP↑, *ALAT↓, *AST↓, *LDH↑, *CRP↓, *COX2↓, *GSH↑, *ROS↓, *Imm↑, *Dose↝, *eff↑, *neuroP↑, *cognitive↑, *IL6↓, *TNF-α↓,

Showing Research Papers: 101 to 150 of 697
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 697

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

HSPD1 / HSP60↓, 2,   HTRA↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   Catalase↑, 1,   Ferroptosis↑, 2,   GPx4↓, 2,   GSH↓, 3,   H2O2↓, 1,   HO-1↓, 3,   MDA↓, 1,   MDA↑, 3,   NQO1↓, 1,   NRF2↓, 4,   OXPHOS↑, 1,   ROS↑, 18,   ROS⇅, 1,   SOD↓, 1,   SOD↑, 1,   SOD2↓, 1,   TAC↓, 1,   TOS↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↑, 1,   FTH1↓, 1,   NCOA4↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ETC↓, 1,   MMP↓, 8,   MMP↑, 1,   mtDam↑, 1,   Raf↓, 1,   XIAP↓, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↑, 1,   cMyc↓, 2,   glucose↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 3,   HK2↓, 1,   lactateProd↓, 1,   LDHA↓, 1,   PDK1↓, 1,   PKM2↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 6,   Apoptosis↑, 25,   BAX↑, 5,   Bax:Bcl2↑, 1,   Bcl-2↓, 11,   Bcl-2↑, 1,   Bcl-xL↓, 1,   Bcl-xL↑, 1,   Casp↑, 2,   Casp1↓, 1,   Casp3↑, 6,   cl‑Casp3↑, 4,   Casp7↑, 2,   Casp8↑, 3,   Casp9↑, 3,   Cyt‑c↑, 4,   Fas↑, 1,   Ferroptosis↑, 2,   IAP1↓, 1,   IAP2↓, 1,   iNOS↓, 1,   JNK↑, 1,   MAPK↓, 3,   necrosis↑, 1,   p27↑, 1,   survivin↓, 5,   Telomerase↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

CaMKII ↓, 1,   Sp1/3/4↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,   PhotoS↑, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1↑, 2,   LC3B↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   DNMT1↓, 2,   DNMTs↓, 1,   P53↓, 1,   P53↑, 3,   PARP↑, 3,   cl‑PARP↑, 3,   PCNA↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   cycD1/CCND1↓, 5,   P21↑, 5,   TumCCA↓, 1,   TumCCA↑, 11,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH1A1↓, 1,   BRAF↑, 1,   CD133↓, 1,   CSCs↓, 2,   EMT↓, 5,   ERK↓, 2,   FOXO3↑, 1,   Gli1∅, 1,   HH↓, 1,   mTOR↓, 5,   Nanog↓, 1,   OCT4↓, 1,   P70S6K↓, 1,   PI3K↓, 6,   PTCH1↓, 1,   PTEN↓, 1,   Smo↓, 1,   SOX2↓, 1,   STAT3↓, 2,   p‑STAT3↓, 1,   TOP1↓, 1,   TOP2↓, 1,   TumCG↓, 50,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   E-cadherin↑, 3,   FTO↑, 1,   Ki-67↓, 4,   MMP1↓, 1,   MMP2↓, 5,   MMP9↓, 4,   N-cadherin↓, 2,   PCBP1↓, 1,   ROCK1↓, 1,   Snail↓, 1,   TIMP2↑, 1,   TumCI↓, 6,   TumCMig↓, 8,   TumCP↓, 10,   TumMeta↓, 4,   Vim↓, 1,   Zeb1↓, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   EGFR↓, 2,   Endoglin↑, 1,   EPR↑, 1,   Hif1a↓, 3,   VEGF↓, 8,   VEGFR2↓, 1,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   GLUT1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCL20↑, 1,   COX2↓, 2,   CXCR4↓, 1,   ICAM-1↓, 1,   IL10↓, 1,   IL12↑, 1,   IL1β↓, 1,   IL6↓, 1,   Inflam↓, 2,   JAK2↓, 1,   NF-kB↓, 4,   NF-kB↑, 1,   p65↓, 1,   PD-L1↓, 2,   TNF-α↓, 1,  

Protein Aggregation(tgid=19) ⓘ

BACE↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   ChemoSen↑, 6,   Dose↝, 2,   eff?, 1,   eff↓, 1,   eff↑, 5,   eff↝, 2,   Half-Life↓, 1,   MDR1↓, 1,   MRP1/ABCC1↓, 1,   RadioS↑, 4,   selectivity↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BRAF↑, 1,   EGFR↓, 2,   Ferritin↑, 1,   GutMicro↑, 2,   IL6↓, 1,   Ki-67↓, 4,   PD-L1↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiTum↑, 1,   chemoPv↑, 1,   radioP↑, 1,   Risk↓, 1,   toxicity↓, 2,   toxicity↝, 1,   TumVol↓, 3,  
Total Targets: 187

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSH↑, 1,   HO-1↑, 1,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 2,   SOD↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   LDH↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 2,   CRP↓, 1,   IL6↓, 1,   Imm↑, 1,   Inflam↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,   eff↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   CRP↓, 1,   IL6↓, 1,   LDH↑, 1,  

Functional Outcomes(tgid=23) ⓘ

cardioP↑, 1,   cognitive↑, 1,   hepatoP↑, 1,   neuroP↑, 2,   toxicity↓, 4,  
Total Targets: 27

Scientific Paper Hit Count for: TumCG, Tumor cell growth
29 Curcumin
25 Magnetic Fields
17 Phenethyl isothiocyanate
16 Quercetin
14 Berberine
14 EGCG (Epigallocatechin Gallate)
13 Silver-NanoParticles
13 Chemotherapy
13 Sulforaphane (mainly Broccoli)
13 Shikonin
12 Vitamin C (Ascorbic Acid)
12 Magnetic Field Rotating
12 Bicarbonate(Sodium)
11 Alpha-Lipoic-Acid
11 Baicalein
10 Capsaicin
10 Apigenin (mainly Parsley)
9 Cucurbitacin
9 Silymarin (Milk Thistle) silibinin
9 Dichloroacetate
9 Deguelin
9 Garcinol
8 Astragalus
8 Artemisinin
8 Resveratrol
8 salinomycin
8 diet FMD Fasting Mimicking Diet
8 Phenylbutyrate
8 Pterostilbene
8 Urolithin
7 Allicin (mainly Garlic)
7 HydroxyCitric Acid
7 Ashwagandha(Withaferin A)
7 immunotherapy
7 Boron
7 Boswellia (frankincense)
7 Crocetin
7 Gambogic Acid
6 Radiotherapy/Radiation
6 Metformin
6 Cisplatin
6 Betulinic acid
6 Chrysin
6 Coenzyme Q10
6 Gemcitabine (Gemzar)
6 diet Methionine-Restricted Diet
6 Sulfasalazine
6 Magnolol
6 Lycopene
6 Magnesium
6 Rosmarinic acid
6 α-Santalol/Sandalwood oil
5 chitosan
5 Melatonin
5 Berbamine
5 Beta-Caryophyllene
5 Centella asiatica / Gotu kola → asiaticoside
5 Citric Acid
5 Dandelion Root
5 Eugenol
5 Fisetin
5 Honokiol
5 Juglone
4 3-bromopyruvate
4 Astaxanthin
4 Atorvastatin
4 Dipyridamole
4 Brucea javanica
4 Butyrate
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Docosahexaenoic Acid
4 Disulfiram
4 Emodin
4 Luteolin
4 Nimbolide
4 Piperine
4 Piperlongumine
4 Selenite (Sodium)
4 Thymoquinone
4 Vitamin K2
4 VitK3,menadione
3 Caffeic acid
3 Diclofenac
3 doxorubicin
3 Paclitaxel
3 Baicalin
3 Bufalin/Huachansu
3 brusatol
3 Bruteridin(bergamot juice)
3 Carvacrol
3 Celastrol
3 Chlorogenic acid
3 Selenium NanoParticles
3 Copper and Cu NanoParticles
3 Photodynamic Therapy
3 tamoxifen
3 Ellagic acid
3 eicosapentaenoic acid
3 Genistein (soy isoflavone)
3 Geraniol
3 Graviola
3 Hydrogen Gas
3 Niclosamide (Niclocide)
3 Propyl gallate
3 Plumbagin
3 Terpinen-4-ol / Tea Tree Oil
3 Aflavin-3,3′-digallate
2 2-DeoxyGlucose
2 Auranofin
2 Fenbendazole
2 Andrographis
2 Anethole/trans-Anethole
2 Fennel Oil/Foeniculum vulgare
2 Ascorbyl Palmitate
2 Biochanin A
2 Bifidobacterium
2 Bromelain
2 α-Bisabolol / Chamomile oil
2 Carnosic acid
2 Cinnamon
2 Cyclopamine
2 Oxygen, Hyperbaric
2 diet Short Term Fasting
2 D-limonene
2 Gallic acid
2 Galloflavin
2 Hydroxycinnamic-acid
2 HydroxyTyrosol
2 Linalool
2 Methylene blue
2 Oroxylin-A
2 Oleuropein
2 Orlistat
2 Psoralidin
2 Hyperthermia
2 EMF
2 Oxaliplatin
2 Spermidine
2 Ursolic acid
2 Whole Body Vibration
1 1,8-Cineole
1 5-fluorouracil
1 Anzaroot, Astragalus fasciculifolius Bioss
1 octreotide
1 Acetyl-l-carnitine
1 DTS(dibenzyl trisulphide) from Anamu
1 Anti-oxidants
1 5-Aminolevulinic acid
1 Aloe anthraquinones
1 beta-glucans
1 temozolomide
1 Bacopa monnieri
1 Caffeine
1 urea
1 Cat’s Claw
1 Cannabidiol
1 Celecoxib
1 Chocolate
1 Calorie Restriction Mimetics
1 Carvone
1 Bicalutamide
1 CUSP9
1 Dichloroacetophenone(2,2-)
1 Dasatinib/Phyrago
1 Bortezomib
1 Date Fruit Extract
1 diet Ketogenic
1 diet Plant based
1 Aspirin
1 Zinc
1 Echinacea
1 Evodiamine
1 PXD, phenoxodiol
1 Sorafenib (brand name Nexavar)
1 Electrical Pulses
1 erastin
1 Eurycomanone
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Ginger/6-Shogaol/Gingerol
1 Glabrescione B
1 Grapeseed extract
1 Inositol
1 itraconazole
1 Ivermectin
1 Laetrile B17 Amygdalin
1 Licorice
1 mebendazole
1 metronomic chemo
1 Methylglyoxal
1 Mushroom Chaga
1 Naringin
1 Noscapine
1 Parthenolide
1 raloxifen
1 Salvia officinalis
1 Vorinostat
1 Selenium
1 irinotecan
1 Salvia miltiorrhiza
1 Saikosaponin B1 and D
1 Sutherlandioside D
1 cetuximab
1 Taurine
1 Tomatine
1 Tumor Treating Fields
1 Turmerones
1 Vitamin B1/Thiamine
1 Vitamin B5,Pantothenic Acid
1 Transarterial Chemoembolization
1 γ-Tocotrienol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:323  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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