TumCMig Cancer Research Results

TumCMig, Tumor cell migration: Click to Expand ⟱
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Tumor cell migration is a critical process in cancer progression and metastasis, which is the spread of cancer cells from the primary tumor to distant sites in the body.
Scientific Papers found: Click to Expand⟱
5868- CA,    Carnosic acid inhibits the proliferation and migration capacity of human colorectal cancer cells
- in-vitro, Colon, Caco-2 - in-vitro, Colon, HT29 - in-vitro, CRC, LoVo
Apoptosis↑, TumCMig↓, uPA↓, MMPs↓, COX2↓, TumCA↓, MMP9↓, MMP2↓, chemoPv↑,
5869- CA,    Carnosic Acid Induces Antiproliferation and Anti-Metastatic Property of Esophageal Cancer Cells via MAPK Signaling Pathways
- in-vitro, ESCC, KYSE150
TumCP↓, Apoptosis↓, TumCMig↓, TumCCA↑, DNAdam↑, MAPK↓, γH2AX↑, TumMeta↓, TumCI↓, P21↑, ROS↑, EMT↓, ChemoSen↑,
5774- CA,  CAPE,    Caffeic Acid Versus Caffeic Acid Phenethyl Ester in the Treatment of Breast Cancer MCF-7 Cells: Migration Rate Inhibition
- NA, BC, MCF-7
TumCMig↓, Wound Healing↑, eff↑, tumCV↓,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
5849- CAP,    The Impact of TRPV1 on Cancer Pathogenesis and Therapy: A Systematic Review
- Review, Var, NA
TRPV1↑, Ca+2↑, TumCD↑, TumCCA↑, Apoptosis↑, P53↑, Fas↑, PI3K↑, AR↑, STAT3↓, ROS↑, MMP↓, ATP↓, CHOP↑, TumCMig↓, Twist↓, Snail↓, MMP2↓, MMP9↓, E-cadherin↑,
5845- CAP,    Unveiling the Molecular Mechanisms Driving the Capsaicin-Induced Immunomodulatory Effects on PD-L1 Expression in Bladder and Renal Cancer Cell Lines
- in-vivo, RCC, A498 - in-vitro, RCC, T24/HTB-9 - NA, Bladder, 5637
TRPV1↑, TumCP↓, Casp↑, Apoptosis↑, SIRT1↓, MMP2↓, MMP9↓, TumCMig↓, TumCCA↑, ROS↑, DNAdam↑, PD-L1↑, eff↓,
5204- CAP,    Low-concentration capsaicin promotes colorectal cancer metastasis by triggering ROS production and modulating Akt/mTOR and STAT-3 pathways
- in-vitro, Colon, SW480 - in-vitro, Colon, CT26
TumCP↓, TumCMig↑, TumCI↑, EMT↑, MMP2↓, MMP9↑, STAT3↑, TumMeta↑, ROS↑,
5203- CAP,    Capsaicin Promotes Apoptosis and Inhibits Cell Migration via the Tumor Necrosis Factor-Alpha (TNFα) and Nuclear Factor Kappa B (NFκB) Signaling Pathway in Oral Cancer Cells
- in-vitro, OS, KB
tumCV↓, TNF-α↓, NF-kB↓, selectivity↑, Apoptosis↑, TumCMig↓,
5202- CAP,    Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways
- vitro+vivo, Bladder, 5637 - in-vitro, Bladder, T24/HTB-9
antiOx↑, Inflam↓, AntiCan↓, TRPV1↑, TumCP↓, TumCCA↑, ROS↑, FOXO3↑, TumCMig↓,
1263- CAP,    Capsaicin inhibits the migration and invasion via the AMPK/NF-κB signaling pathway in esophagus sequamous cell carcinoma by decreasing matrix metalloproteinase-9 expression
- in-vitro, ESCC, Eca109
TumCMig↓, TumCI↓, MMP9↓, p‑AMPK↑, SIRT1↑, NF-kB↓, p‑IκB↑,
1264- CAP,    Capsaicin modulates proliferation, migration, and activation of hepatic stellate cells
- in-vitro, HCC, NA
TumCP↓, TumCMig↓, TumCCA↑, MMP∅, MMP2↓, MMP9↓, α-SMA↓, COL1A1↓, COL3A1↓, TIMP1↓,
1518- CAP,    Capsaicin-mediated tNOX (ENOX2) up-regulation enhances cell proliferation and migration in vitro and in vivo
- in-vitro, CRC, HCT116
ENOX2↑, TumCP↑, TumCMig↑, Dose?, eff↑,
1517- CAP,    Capsaicin Inhibits Multiple Bladder Cancer Cell Phenotypes by Inhibiting Tumor-Associated NADH Oxidase (tNOX) and Sirtuin1 (SIRT1)
- in-vitro, Bladder, TSGH8301 - in-vitro, CRC, T24/HTB-9
ENOX2↓, TumCCA↑, ERK↓, p‑FAK↓, p‑pax↓, TumCMig↓, EMT↓, SIRT1↓, Dose∅, ROS↑, MMP↓, Bcl-2↓, Bak↑, cl‑PARP↑, Casp3↑, SIRT1↓, ac‑P53↑, BIM↑, p‑RB1↓, cycD1/CCND1↓, Dose∅, β-catenin/ZEB1↓, N-cadherin↓, E-cadherin↑,
5885- CAR,    Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
TRPM7↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, toxicity↓, *Inflam↓, AntiDiabetic↑, cardioP↑, neuroP↑, selectivity↑, Apoptosis↑, p‑Cofilin↑, F-actin↓, PI3K↓, Akt↓, MEK↓, MAPK↓,
5895- CAR,    Carvacrol as a Therapeutic Candidate in Breast Cancer: Insights into Subtype-Specific Cellular Modulation
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
TumCG↓, TumCMig↓, Apoptosis↑, Bax:Bcl2↑, ROS↓, CD44↓, CSCs↓,
5894- CAR,    Targeting Gastrointestinal Cancers with Carvacrol: Mechanistic Insights and Therapeutic Potential
- Review, Var, NA
AntiCan↑, Apoptosis↑, Inflam↓, angioG↓, TumMeta↓, selectivity↑, BioAv↑, ChemoSen↑, Dose↝, TumCP↓, hepatoP↑, Casp3↑, Casp9↑, Bcl-2↓, ROS↑, GSH↓, BAX↑, Casp7↑, Casp8↑, Cyt‑c↑, Fas↑, FADD↑, P53↑, Bcl-2↓, TumMeta↓, TumCMig↓, TumCI↓, E-cadherin↑, TIMP2↑, TIMP3↑, N-cadherin↓, ZEB2↓, *lipid-P↓, *AST↓, *ALAT↓, *ALP↓, *LDH↓, *SOD↑, *Catalase↑, *GPx↑, *GSR↑, selectivity↑, cl‑PARP↑, ERK↓, p38↑, OS↑, AFP↓, COX2↓, VEGF↓, PCNA↓, Ki-67↓, TNF-α↓, BioAv↓,
5890- CAR,    Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways
- Review, Var, NA
selectivity↑, TumCG↓, *Inflam↓, *antiOx↑, TumCCA↑, TumCMig↓, TumCI↓, angioG↓,
5912- CAR,    Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation migration and invasion
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
TRPM7↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, p‑Cofilin↑, RAS↓, MEK↓, MAPK↓, PI3K↓, Akt↓,
1103- CBD,    Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway
- vitro+vivo, NA, NA
Apoptosis↑, TumCP↓, TumCMig↓, TumMeta↓, EMT↓, E-cadherin↑, N-cadherin↓, Snail↓, Vim↓, Hif1a↓, Wnt/(β-catenin)↓, AXIN1↑, TumVol↓, TumW↓,
5954- CEL,    The molecular mechanisms of celecoxib in tumor development
- Review, Var, NA
TumCP↓, TumCMig↓, TumCI↓, COX2↓, p‑NF-kB↓, Akt↓, MMP2↓, MMP9↓, Apoptosis↑, mitResp↑, ER Stress↑, TumAuto↑, ChemoSen↑, Inflam↓, PGE2↓, chemoPv↑, toxicity↓, Risk↓, PI3K↓, RadioS↑, TumCMig↓, TumCI↓, cJun↓, Sp1/3/4↓, ROS↑, MMP↓, MPT↑, Ca+2↑, Glycolysis↓, ATP↓, CSCs↓, Wnt/(β-catenin)↓, EMT↓, toxicity↝,
1105- CEL,    Celecoxib inhibits the epithelial-to-mesenchymal transition in bladder cancer via the miRNA-145/TGFBR2/Smad3 axis
- in-vitro, BC, NA
COX2↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, miR-145↑, TGF-β↓, SMAD3↓,
5940- Cela,    Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway
- in-vivo, Pca, PC3
Dose↝, TumVol↓, TumW↓, angioG↓, VEGF↓, TumCMig↓, TumCP↓, TumCI↓, Akt↓, mTOR↓, P70S6K↓,
5941- Cela,    Celastrol inhibits migration and invasion through blocking the NF-κB pathway in ovarian cancer cells
- in-vitro, Ovarian, SKOV3 - in-vitro, Ovarian, OVCAR-3
TumCMig↓, TumCI↓, NF-kB↓, p65↓, MMP9↓, eff↑, AntiTum↑, Inflam↓, AntiDiabetic↑,
6006- CGA,    Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF-κB signaling pathway
- in-vitro, BC, NA
NF-kB↓, AntiTum↑, Apoptosis↑, TumCMig↓, TumCI↓, EMT↓,
6010- CGA,    The Biological Activity Mechanism of Chlorogenic Acid and Its Applications in Food Industry: A Review
- Review, Nor, NA
*antiOx↑, *hepatoP↑, *RenoP↑, AntiTum↑, *glucose↝, *Inflam↓, *neuroP↑, *ROS↓, *Keap1↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *MDA↓, *p‑ERK↑, *GRP78/BiP↑, *CHOP↑, *GRP94↑, *Casp3↓, *Casp9↓, *HGF/c-Met↑, *TNF-α↓, *TLR4↓, *MAPK↓, *IL1β↓, *iNOS↓, TCA↓, Glycolysis↓, Bcl-2↓, BAX↑, MAPK↑, JNK↑, CSCs↓, Nanog↓, SOX2↓, CD44↓, OCT4↓, P53↑, P21↑, *SOD1↑, *AGEs↓, *GLUT2↑, *HDL↑, *Fas↓, *HMG-CoA↓, *NF-kB↓, *HO-1↓, *COX2↓, *TLR4↓, *BioAv↑, *BioAv↝, TumCP↓, TumCMig↓, TumCI↓,
6014- CGA,    Exploring the Pharmacological Potential of Chlorogenic acid as an Anti-Cancer Agent and a Call for Advance Research
- Review, Var, NA
AntiCan↑, *hepatoP↑, *Bacteria↓, *antiOx↓, *AntiDiabetic↑, Apoptosis↓, TumCG↓, angioG↓, TumCI↓, TumCMig↓, ROS↝, Inflam↝,
6012- CGA,    Chlorogenic Acid as a Potential Therapeutic Agent for Cholangiocarcinoma
- in-vitro, CCA, HCC9810
TumCP↓, TumCMig↓, TumCI↓, EMT↓, Apoptosis↑, TumCCA↑, AKR1B10↓, Akt↓, mtDam↑, BAX↑, Casp9↑, Casp3↑, Bcl-2↓,
6030- CGA,    Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF‑κB signaling pathway
- vitro+vivo, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-453 - in-vitro, Nor, MCF10
NF-kB↓, AntiTum↑, tumCV↓, TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, EMT↓, TumCG↓, OS↑, TumMeta↓, CD4+↑, CD8+↑, Imm↑,
1106- CGA,    Chlorogenic Acid Inhibits Epithelial-Mesenchymal Transition and Invasion of Breast Cancer by Down-Regulating LRP6
- vitro+vivo, BC, MCF-7
E-cadherin↑, ZO-1↑, Zeb1↓, N-cadherin↓, Vim↓, Snail↓, Slug↓, MMP2↓, MMP9↓, TumCMig↓, TumCI↓, LRP6↓, p‑LRP6↓, β-catenin/ZEB1↓, TumVol↓, TumW↓,
4489- Chit,  SeNPs,    Inhibiting Metastasis and Improving Chemosensitivity via Chitosan-Coated Selenium Nanoparticles for Brain Cancer Therapy
- in-vitro, GBM, U87MG
TumCG↓, TumCMig↓, TumCI↓, ChemoSen↑, *BBB↑, eff↑, eff↑, eff↑, selectivity↑, MMP2↓, MMP9↓, EPR↑,
6075- CHL,  docx,    The effect of the combination therapy with chlorophyllin, a glutathione transferase P1-1 inhibitor, and docetaxel on triple-negative breast cancer invasion and metastasis in vivo/in vitro
- vitro+vivo, BC, 4T1
TumCMig↓, eff↑, TumMeta↓, TumCCA↑, Trx↓, ROS↓, TumCD↑, GSTP1/GSTπ↓,
6073- CHL,  GEM,    Chlorophyllin exerts synergistic anti-tumor effect with gemcitabine in pancreatic cancer by inducing cuproptosis
- in-vitro, PC, NA
ChemoSen↑, eff↑, AntiTum↑, TumCP↓, TumCI↓, TumCMig↓, Apoptosis↑, GSH↓, ROS↑, HSP70/HSPA5↑,
2590- CHr,    Chrysin suppresses proliferation, migration, and invasion in glioblastoma cell lines via mediating the ERK/Nrf2 signaling pathway
- in-vitro, GBM, T98G - in-vitro, GBM, U251 - in-vitro, GBM, U87MG
TumCP↓, TumCMig↓, TumCI↓, NRF2↓, HO-1↓, NADPH↓, ERK↓,
2784- CHr,    Chrysin targets aberrant molecular signatures and pathways in carcinogenesis (Review)
- Review, Var, NA
Apoptosis↑, TumCMig↓, *toxicity↝, ChemoSen↑, *BioAv↓, Dose↝, neuroP↑, *P450↓, *ROS↓, *HDL↑, *GSTs↑, *SOD↑, *Catalase↑, *MAPK↓, *NF-kB↓, *PTEN↑, *VEGF↑, ROS↑, MMP↓, Ca+2↑, selectivity↑, PCNA↓, Twist↓, EMT↓, CDKN1C↑, p‑STAT3↑, MMP2↓, MMP9↓, eff↑, cycD1/CCND1↓, hTERT/TERT↓, CLDN1↓, TumVol↓, OS↑, COX2↓, eff↑, CDK2↓, CDK4↓, selectivity↑, TumCCA↑, E-cadherin↑, HK2↓, HDAC↓,
3258- CHr,  PBG,    Chrysin Induced Cell Apoptosis and Inhibited Invasion Through Regulation of TET1 Expression in Gastric Cancer Cells
- in-vitro, GC, MKN45
TET1↑, Apoptosis↑, TumCI↓, TumCMig↓,
1584- Citrate,    Anticancer effects of high-dose extracellular citrate treatment in pancreatic cancer cells under different glucose concentrations
- in-vitro, PC, MIA PaCa-2 - in-vitro, PC, PANC1
tumCV↓, i-Ca+2↓, TumCMig↓, CD133↓, pH↑, eff↑, Ki-67↓, eff↑,
133- CUR,    Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis
- in-vitro, Pca, DU145 - in-vitro, Pca, PC3
miR-143↑, PDK1↓, FOXD3↑, TumCP↓, TumCMig↓, *Inflam↓, *antiOx↑, *chemoPv↑, RadioS↑, ChemoSen↑,
158- CUR,    Curcumin-targeting pericellular serine protease matriptase role in suppression of prostate cancer cell invasion, tumor growth, and metastasis
- vitro+vivo, Pca, LNCaP - in-vitro, Pca, PC3
MMP9↓, Matr↓, Inflam↓, antiOx↓, NF-kB↓, COX2↓, iNOS↓, TumCMig↓, TumCI↓,
11- CUR,    Curcumin inhibits hypoxia-induced epithelial‑mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway
- in-vitro, PC, PANC1
HH↓, Shh↓, Smo↓, Gli1↓, N-cadherin↓, E-cadherin↑, Vim↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, chemoPv↑,
9- CUR,    Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo
- vitro+vivo, MG, U87MG - vitro+vivo, MG, T98G
HH↓, Shh↓, Gli1↓, cycD1/CCND1↓, Bcl-2↓, FOXM1↓, Bax:Bcl2↑, TumCP↓, TumCMig↓, Apoptosis↑, TumVol↑, TumCCA↑, Casp3↑, OS↑,
476- CUR,    The effects of curcumin on proliferation, apoptosis, invasion, and NEDD4 expression in pancreatic cancer
- in-vitro, PC, PATU-8988 - in-vitro, PC, PANC1
TumCMig↓, TumCI↓, Apoptosis↑, NEDD9↓, p‑Akt↓, p‑mTOR↓, PTEN↑, p73↑, β-TRCP↑,
479- CUR,    Curcumin Has Anti-Proliferative and Pro-Apoptotic Effects on Tongue Cancer in vitro: A Study with Bioinformatics Analysis and in vitro Experiments
- in-vitro, Tong, CAL27
TumCP↓, TumCMig↓, Apoptosis↑, TumCCA↑, Bcl-2↓, BAX↑, cl‑Casp3↑,
461- CUR,    Curcumin inhibits prostate cancer progression by regulating the miR-30a-5p/PCLAF axis
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, miR-30a-5p↑, PCLAF↓, Bcl-2↓, Casp3↓, BAX↑, cl‑Casp3↑,
405- CUR,  5-FU,    Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
- vitro+vivo, CRC, HCT116
Apoptosis↑, TumCMig↓, NRF2↑, ROS↑, MET↑, miR-34a↑,
480- CUR,    Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells
- in-vitro, GBM, SNB19
TumCP↓, TumCMig↓, Apoptosis↑, TumCCA↑, NEDD9↓, NOTCH1↓, p‑Akt↓,
447- CUR,  OXA,    Curcumin reverses oxaliplatin resistance in human colorectal cancer via regulation of TGF-β/Smad2/3 signaling pathway
- vitro+vivo, CRC, HCT116
p‑p65↓, Bcl-2↓, Casp3↑, EMT↓, p‑SMAD2↓, p‑SMAD3↓, N-cadherin↓, TGF-β↓, E-cadherin↑, TumVol↓, TumCMig↓,
456- CUR,    Curcumin Promoted miR-34a Expression and Suppressed Proliferation of Gastric Cancer Cells
- vitro+vivo, GC, SGC-7901
miR-34a↑, TumCP↓, TumCMig↓, TumCI↓, TumCCA↑, Bcl-2↓, CDK4/6↓, cycD1/CCND1↓,
455- CUR,    Curcumin Affects Gastric Cancer Cell Migration, Invasion and Cytoskeletal Remodeling Through Gli1-β-Catenin
- in-vitro, GC, SGC-7901
Shh↓, Gli1↓, FOXM1↓, β-catenin/ZEB1↓, TumCMig↓, Apoptosis↑, TumCCA↑, Wnt↓, EMT↓, E-cadherin↑, Vim↓,
454- CUR,    Curcumin-Induced DNA Demethylation in Human Gastric Cancer Cells Is Mediated by the DNA-Damage Response Pathway
- in-vitro, GC, MGC803
TumCMig↓, TumCP↓, ROS↑, mtDam↑, DNAdam↑, Apoptosis↑, ATR↑, P21↑, p‑P53↑, GADD45A↑, p‑γH2AX↑,
451- CUR,    The effect of Curcumin on multi-level immune checkpoint blockade and T cell dysfunction in head and neck cancer
- vitro+vivo, HNSCC, SCC15 - vitro+vivo, HNSCC, SNU1076 - vitro+vivo, HNSCC, SNU1041
TumCMig↓, TumCG↓, PD-L1↓, PD-L2↓, Galectin-9↓, EMT↓, T-Cell↑, TILs↑, PD-1↓, TIM-3↓, CD4+↓, CD25+↓, FoxP3+↓, E-cadherin↑, CD8+↑, IFN-γ↑,

Showing Research Papers: 101 to 150 of 368
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 368

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

AKR1B10↓, 1,  

Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 1,   ENOX2↓, 1,   ENOX2↑, 1,   GSH↓, 2,   GSTP1/GSTπ↓, 1,   HO-1↓, 1,   NADH↓, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↓, 2,   ROS↑, 13,   ROS↝, 1,   Trx↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 2,   MEK↓, 2,   mitResp↑, 1,   MMP↓, 5,   MMP∅, 1,   MPT↑, 2,   mtDam↑, 2,  

Core Metabolism/Glycolysis ⓘ

p‑AMPK↑, 1,   Glycolysis↓, 2,   HK2↓, 1,   NADPH↓, 1,   PDK1↓, 1,   SIRT1↓, 4,   SIRT1↑, 1,   TCA↓, 1,  

Cell Death ⓘ

Akt↓, 5,   p‑Akt↓, 2,   Apoptosis↓, 2,   Apoptosis↑, 24,   Bak↑, 1,   BAX↑, 5,   Bax:Bcl2↑, 2,   Bcl-2↓, 10,   BIM↑, 1,   Casp↑, 2,   Casp3↓, 1,   Casp3↑, 5,   cl‑Casp3↑, 2,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 2,   Cyt‑c↑, 2,   FADD↑, 1,   Fas↑, 2,   hTERT/TERT↓, 1,   iNOS↓, 1,   JNK↑, 1,   MAPK↓, 3,   MAPK↑, 1,   p38↑, 2,   TRPV1↑, 3,   TumCD↑, 2,   β-TRCP↑, 1,  

Kinase & Signal Transduction ⓘ

FOXD3↑, 1,   Sp1/3/4↓, 1,  

Transcription & Epigenetics ⓘ

cJun↓, 1,   Matr↓, 1,   miR-143↑, 1,   miR-145↑, 1,   miR-30a-5p↑, 1,   tumCV↓, 6,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   ER Stress↑, 1,   HSP70/HSPA5↑, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

DNA Damage & Repair ⓘ

ATR↑, 1,   DNAdam↑, 3,   GADD45A↑, 1,   P53↑, 3,   p‑P53↑, 1,   ac‑P53↑, 1,   p73↑, 1,   cl‑PARP↑, 2,   PCLAF↓, 1,   PCNA↓, 2,   γH2AX↑, 1,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 4,   P21↑, 3,   p‑RB1↓, 1,   TumCCA↑, 15,  

Proliferation, Differentiation & Cell State ⓘ

AXIN1↑, 1,   CD133↓, 1,   CD44↓, 2,   CSCs↓, 3,   EMT↓, 13,   EMT↑, 1,   ERK↓, 3,   FOXM1↓, 2,   FOXO3↑, 1,   Gli1↓, 3,   HDAC↓, 1,   HH↓, 2,   LRP6↓, 1,   p‑LRP6↓, 1,   miR-34a↑, 2,   mTOR↓, 1,   p‑mTOR↓, 1,   Nanog↓, 1,   NOTCH1↓, 1,   OCT4↓, 1,   P70S6K↓, 1,   PI3K↓, 3,   PI3K↑, 1,   PTEN↑, 1,   RAS↓, 1,   Shh↓, 3,   Smo↓, 1,   SOX2↓, 1,   STAT3↓, 1,   STAT3↑, 1,   p‑STAT3↑, 1,   TOP1↓, 1,   TOP2↓, 1,   TRPM7↓, 2,   TumCG↓, 7,   Wnt↓, 1,   Wnt/(β-catenin)↓, 2,  

Migration ⓘ

Ca+2↑, 3,   i-Ca+2↓, 1,   CDK4/6↓, 1,   CDKN1C↑, 1,   CLDN1↓, 1,   p‑Cofilin↑, 2,   COL1A1↓, 1,   COL3A1↓, 1,   E-cadherin↑, 10,   F-actin↓, 1,   p‑FAK↓, 1,   Galectin-9↓, 1,   Ki-67↓, 2,   MET↑, 1,   MMP2↓, 11,   MMP9↓, 11,   MMP9↑, 1,   MMPs↓, 1,   N-cadherin↓, 6,   NEDD9↓, 2,   p‑pax↓, 1,   Slug↓, 1,   p‑SMAD2↓, 1,   SMAD3↓, 1,   p‑SMAD3↓, 1,   Snail↓, 3,   TET1↑, 1,   TGF-β↓, 2,   TIMP1↓, 1,   TIMP2↑, 1,   TIMP3↑, 1,   TRIB3↑, 1,   TumCA↓, 1,   TumCI↓, 26,   TumCI↑, 1,   TumCMig↓, 49,   TumCMig↑, 2,   TumCP↓, 23,   TumCP↑, 1,   TumMeta↓, 6,   TumMeta↑, 1,   Twist↓, 2,   uPA↓, 1,   Vim↓, 4,   Zeb1↓, 1,   ZEB2↓, 1,   ZO-1↑, 1,   α-SMA↓, 1,   β-catenin/ZEB1↓, 4,  

Angiogenesis & Vasculature ⓘ

angioG↓, 4,   EPR↑, 1,   Hif1a↓, 1,   VEGF↓, 2,  

Immune & Inflammatory Signaling ⓘ

CD25+↓, 1,   CD4+↓, 1,   CD4+↑, 1,   COX2↓, 6,   FoxP3+↓, 1,   IFN-γ↑, 1,   Imm↑, 1,   Inflam↓, 5,   Inflam↝, 1,   p‑IκB↑, 1,   NF-kB↓, 6,   p‑NF-kB↓, 1,   p65↓, 1,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 1,   PD-L1↑, 1,   PD-L2↓, 1,   PGE2↓, 1,   T-Cell↑, 1,   TILs↑, 1,   TNF-α↓, 2,  

Cellular Microenvironment ⓘ

pH↑, 1,   TIM-3↓, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 1,   ChemoSen↑, 7,   Dose?, 1,   Dose↝, 3,   Dose∅, 2,   eff↓, 1,   eff↑, 12,   RadioS↑, 2,   selectivity↑, 8,  

Clinical Biomarkers ⓘ

AFP↓, 1,   AR↑, 1,   FOXM1↓, 2,   hTERT/TERT↓, 1,   Ki-67↓, 2,   PD-L1↓, 1,   PD-L1↑, 1,   TRIB3↑, 1,  

Functional Outcomes ⓘ

AntiCan↓, 1,   AntiCan↑, 2,   AntiDiabetic↑, 2,   AntiTum↑, 5,   cardioP↑, 1,   chemoPv↑, 3,   hepatoP↑, 1,   neuroP↑, 2,   Obesity↓, 1,   OS↑, 4,   Risk↓, 1,   toxicity↓, 2,   toxicity↝, 1,   TumVol↓, 5,   TumVol↑, 1,   TumW↓, 3,   Wound Healing↑, 1,  

Infection & Microbiome ⓘ

CD8+↑, 2,  
Total Targets: 239

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 4,   Catalase↑, 3,   GPx↑, 2,   GSH↑, 1,   GSR↑, 1,   GSTs↑, 1,   HDL↑, 2,   HO-1↓, 1,   Keap1↓, 1,   lipid-P↓, 1,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 3,   SOD↑, 3,   SOD1↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   glucose↝, 1,   GLUT2↑, 1,   HMG-CoA↓, 1,   LDH↓, 1,  

Cell Death ⓘ

Casp3↓, 1,   Casp9↓, 1,   Fas↓, 1,   HGF/c-Met↑, 1,   iNOS↓, 1,   MAPK↓, 2,   TRPV1↑, 1,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   GRP78/BiP↑, 1,   GRP94↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

p‑ERK↑, 1,   PTEN↑, 1,  

Migration ⓘ

Ca+2↑, 1,  

Angiogenesis & Vasculature ⓘ

VEGF↑, 1,  

Barriers & Transport ⓘ

BBB↓, 1,   BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IL1β↓, 1,   Inflam↓, 5,   NF-kB↓, 2,   TLR4↓, 2,   TNF-α↓, 1,  

Protein Aggregation ⓘ

AGEs↓, 1,   Aβ↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 2,   Half-Life↓, 1,   P450↓, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   GutMicro↑, 1,   LDH↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 1,   cardioP↑, 1,   chemoPv↑, 1,   hepatoP↑, 2,   neuroP↑, 2,   RenoP↑, 1,   toxicity↝, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 64

Scientific Paper Hit Count for: TumCMig, Tumor cell migration
21 Curcumin
13 Quercetin
13 Shikonin
11 Berberine
10 Capsaicin
10 Honokiol
9 Silymarin (Milk Thistle) silibinin
8 Apigenin (mainly Parsley)
8 Resveratrol
8 EGCG (Epigallocatechin Gallate)
8 Betulinic acid
8 Magnolol
8 Magnetic Fields
8 Sulforaphane (mainly Broccoli)
7 Ashwagandha(Withaferin A)
7 Thymoquinone
7 Urolithin
6 Propolis -bee glue
6 Chlorogenic acid
6 Fisetin
6 Piperlongumine
6 Rosmarinic acid
5 Silver-NanoParticles
5 Alpha-Lipoic-Acid
5 Artemisinin
5 Baicalein
5 Carvacrol
5 Metformin
5 Phenethyl isothiocyanate
5 Piperine
4 Astragalus
4 Gemcitabine (Gemzar)
4 Astaxanthin
4 Boron
4 Luteolin
4 Pterostilbene
3 Radiotherapy/Radiation
3 Berbamine
3 Bacopa monnieri
3 brusatol
3 Caffeic acid
3 Chrysin
3 Deguelin
3 Ferulic acid
3 Garcinol
3 HydroxyTyrosol
3 Lycopene
3 salinomycin
3 Aflavin-3,3′-digallate
2 Allicin (mainly Garlic)
2 Andrographis
2 Arctigenin
2 Baicalin
2 Bufalin/Huachansu
2 Genistein (soy isoflavone)
2 Boswellia (frankincense)
2 Paclitaxel
2 Carnosic acid
2 Celecoxib
2 Celastrol
2 Chlorophyllin
2 Docetaxel
2 5-fluorouracil
2 Disulfiram
2 Copper and Cu NanoParticles
2 Ellagic acid
2 Emodin
2 Ginkgo biloba
2 Grapeseed extract
2 Juglone
2 Plumbagin
2 Magnetic Field Rotating
2 Nimbolide
2 Psoralidin
2 Cisplatin
2 Parthenolide
2 Ursolic acid
2 Vitamin C (Ascorbic Acid)
2 VitK3,menadione
1 Auranofin
1 Ajoene (compound of Garlic)
1 dibenzyl trisulphide(DTS) from Anamu
1 Aspirin -acetylsalicylic acid
1 Atorvastatin
1 Aloe anthraquinones
1 Biochanin A
1 Bevacizumab (brand Avastin)
1 Brucea javanica
1 Bromelain
1 selenomethionine
1 Bruteridin(bergamot juice)
1 Butyrate
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Cannabidiol
1 chitosan
1 Selenium NanoParticles
1 Citric Acid
1 Oxaliplatin
1 Docosahexaenoic Acid
1 diet Short Term Fasting
1 Evodiamine
1 erastin
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Gambogic Acid
1 Ginger/6-Shogaol/Gingerol
1 γ-linolenic acid (Borage Oil)
1 Graviola
1 Proanthocyanidins
1 Hydrogen Gas
1 HydroxyCitric Acid
1 Indole-3-carbinol
1 Licorice
1 Melatonin
1 doxorubicin
1 immunotherapy
1 Myricetin
1 Naringin
1 Niclosamide (Niclocide)
1 Oroxylin A
1 Orlistat
1 Propyl gallate
1 temozolomide
1 isoflavones
1 raloxifen
1 tamoxifen
1 Germacranolide
1 Rutin
1 Sanguinarine
1 Sulfasalazine
1 Selenite (Sodium)
1 Thymol-Thymus vulgaris
1 Arsenic trioxide
1 Zinc
1 β‐Elemene
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:326  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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