N-cadherin Cancer Research Results

N-cadherin, N-cadherin: Click to Expand ⟱
Source:
Type:
Also known as Cadherin2 (CDH2).
N-cadherin is a type of cell adhesion molecule that plays a crucial role in the development and maintenance of tissue structure. In the context of cancer, N-cadherin has been implicated in the progression and metastasis of various types of tumors.
N-cadherin expression is increased in various types of cancer.
Normally, N-cadherin is expressed in mesenchymal cells, such as fibroblasts and smooth muscle cells. However, in cancer cells, N-cadherin expression is often upregulated, which can contribute to the epithelial-to-mesenchymal transition (EMT). EMT is a process by which epithelial cells acquire a more mesenchymal phenotype, which is characterized by increased motility, invasiveness, and resistance to apoptosis.
The expression of N-cadherin in cancer cells is closely associated with tumorigenesis and metastasis. Additionally, the soluble N-cadherin level in the serum of cancer patients is much higher than that in the serum of healthy patients, revealing a positive relation with poor prognosis.
Scientific Papers found: Click to Expand⟱
2048- PB,    Sodium Phenylbutyrate Inhibits Tumor Growth and the Epithelial-Mesenchymal Transition of Oral Squamous Cell Carcinoma In Vitro and In Vivo
- in-vitro, OS, CAL27 - in-vitro, Oral, HSC3 - in-vitro, OS, SCC4 - in-vivo, NA, NA
*NH3↓, *HDAC↓, *ER Stress↓, Apoptosis?, Bcl-2↓, cl‑Casp3↑, TGF-β↑, N-cadherin↓, E-cadherin↑, TumVol↓, ChemoSen↑,
4926- PEITC,    PEITC inhibits the invasion and migration of colorectal cancer cells by blocking TGF-β-induced EMT
- in-vitro, CRC, SW48
TumCI↓, TumCMig↓, EMT↓, Smad1↓, AntiCan↑, Snail↓, Slug↓, Zeb1↓, ZEB2↓, TGF-β1↓, Synergy↑, E-cadherin↑, N-cadherin↓, Vim↓,
9012- Phyco,    Phycocyanin from Arthrospira platensis as Potential Anti-Cancer Drug: Review of In Vitro and In Vivo Studies
- Review, Var, NA
*Ingr↝, *antiOx↑, *Inflam↓, Imm↑, AntiCan↑, *toxicity↓, *Dose↝, *GutMicro↑, *IBI↑, Apoptosis↑, TumCCA↑, DNArepair↓, ROS↑, Cyt‑c↑, BAX↑, cl‑PARP1↑, CellShr↑, TumCMig↓, COX2/PTGS2↓, E-cadherin↑, MMP2↓, MMP9↓, HIF-1↓, angioG↓, MCP1/CCL2↓, MIP-1β↑, Ca+2↑, Cal9↑, Wnt↓, β-catenin/ZEB1↓, PPARα↑, PPARγ↑, eff↝, Half-Life↓, Synergy↑, ChemoSen↑, chemoP↑, EMT↓, N-cadherin↓, E-cadherin↑, TumCMig↓, TumCI↓, selectivity↑,
1131- PI,    Piperlongumine‑loaded nanoparticles inhibit the growth, migration and invasion and epithelial‑to‑mesenchymal transition of triple‑negative breast cancer cells
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549
TumCG↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, Slug↓, N-cadherin↓, β-catenin/ZEB1↓, SMAD3↓, E-cadherin↑, EMT↓,
2948- PL,    The promising potential of piperlongumine as an emerging therapeutics for cancer
- Review, Var, NA
tumCV↓, TumCP↓, TumCI↓, angioG↓, EMT↓, TumMeta↓, *hepatoP↑, *lipid-P↓, *GSH↑, cardioP↑, CycB/CCNB1↓, cycD1/CCND1↓, CDK2↓, CDK1↓, CDK4↓, CDK6↓, PCNA↓, Akt↓, mTOR↓, Glycolysis↓, NF-kB↓, IKKα↓, JAK1↓, JAK2↓, STAT3↓, ERK↓, cFos↓, Slug↓, E-cadherin↑, TOP2↓, P53↑, P21↑, Bcl-2↓, BAX↑, Casp3↑, Casp7↑, Casp8↑, p‑HER2/EBBR2↓, HO-1↑, NRF2↑, BIM↑, p‑FOXO3↓, Sp1/3/4↓, cMyc↓, EGFR↓, survivin↓, cMET↓, NQO1↑, SOD2↑, TrxR↓, MDM2↓, p‑eIF2α↑, ATF4↑, CHOP/DDIT3↑, MDA↑, Ki-67↓, MMP9↓, Twist↓, SOX2↓, Nanog↓, OCT4↓, N-cadherin↓, Vim↓, Snail↓, TumW↓, TumCG↓, HK2↓, RB1↓, IL6↓, IL8↓, SOD1↑, RadioS↑, ChemoSen↑, toxicity↓, Sp1/3/4↓, GSH↓, SOD↑,
2952- PL,    Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization
- in-vitro, Bladder, T24/HTB-9 - in-vivo, Bladder, NA
TumCP↓, TumCCA↑, TumCMig↓, TumCI↓, ROS↑, Slug↓, β-catenin/ZEB1↓, Zeb1↓, N-cadherin↓, F-actin↓, GSH↓, EMT↓, CLDN1↓, ZO-1↓,
3368- QC,    The potential anti-cancer effects of quercetin on blood, prostate and lung cancers: An update
- Review, Var, NA
*Inflam↓, *antiOx↑, *AntiCan↑, Casp3↓, p‑Akt↓, p‑mTOR↓, p‑ERK↓, β-catenin/ZEB1↓, Hif1a↓, AntiAg↓, VEGFR2/KDR/Flk1↓, EMT↓, EGFR↓, MMP2↓, MMP↓, TumMeta↓, MMPs↓, Akt↓, Snail↓, N-cadherin↓, Vim↓, E-cadherin↑, STAT3↓, TGF-β↓, ROS↓, P53↑, BAX↑, PKCδ↓, PI3K↓, COX2/PTGS2↓, cFLIP↓, cycD1/CCND1↓, cMyc↓, IL6↓, IL10↓, Cyt‑c↑, TumCCA↑, DNMTs↓, HDAC↓, ac‑H3↑, ac‑H4↑, Diablo↑, Casp3↑, Casp9↑, PARP1↑, Synergy↑, PTEN↑, VEGF↓, NO↓, iNOS↓, ChemoSen↑, Synergy↑, Synergy↑, Synergy↑, uPA↓, CXCR4↓, CXCL12↓, CLDN2↓, CDK6↓, MMP9↓, TSP-1↑, Ki-67↓, PCNA↓, ROS↑, ER Stress↑,
95- QC,    Quercetin, a natural dietary flavonoid, acts as a chemopreventive agent
- in-vitro, Pca, PC3
p‑ERK↓, p‑STAT3↓, p‑Akt↓, N-cadherin↓, Vim↓, cycD1/CCND1↓, Snail↓, Slug↓, Twist↓, PCNA↓, EGFR↓, chemoPv↑,
99- QC,    Quercetin Inhibits Epithelial-to-Mesenchymal Transition (EMT) Process and Promotes Apoptosis in Prostate Cancer via Downregulating lncRNA MALAT1
- in-vitro, Pca, PC3
EMT↓, E-cadherin↑, N-cadherin↓, Ki-67↓, PI3K/Akt↓, MALAT1↓, TumCG↓,
80- QC,    Quercetin reverses EGF-induced epithelial to mesenchymal transition and invasiveness in prostate cancer (PC-3) cell line via EGFR/PI3K/Akt pathway
- in-vitro, Pca, PC3
Vim↓, ERK↓, Snail↓, Slug↓, Twist↓, EGFR↓, p‑Akt↓, EGFR↓, N-cadherin↓, TumMeta↓, EMT↓,
7150- RES,    Modulation of the PI3K/Akt signaling pathway by resveratrol in cancer: molecular mechanisms and therapeutic opportunity
- Review, Var, NA
AntiTum↑, PI3K↓, Akt↓, *AntiAge↑, *SIRT1↑, *lipid-P↓, *ROS↓, *BioAv↓, *NRF2↑, *HO-1↑, SOD↑, HDAC1↓, PTEN↑, P53↑, TumCCA↑, TumCI↓, TumMeta↓, EMT↓, MMPs↓, MMP9↓, angioG↓, VEGF↓, EGFR↓, FGF21↓, HIF-1↓, *neuroP↑, *cardioP↑, BMPs↑, ROS↑, Vim↓, N-cadherin↓, MMP3↓, MMP13↓, E-cadherin↑, Ki-67↓,
101- RES,    Resveratrol inhibits the hedgehog signaling pathway and epithelial-mesenchymal transition and suppresses gastric cancer invasion and metastasis
- in-vitro, GC, SGC-7901
HH↓, Gli1↓, EMT↓, Snail↓, N-cadherin↓, E-cadherin↑, TumCI↓, TumMeta↓,
105- RES,  QC,    The Effect of Resveratrol and Quercetin on Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem Cell
- in-vitro, Pca, PANC1
N-cadherin↓, TNF-α↓, ACTA2↓, EMT↓, CD133↓, CSCs↓,
1047- RES,    Resveratrol induces PD-L1 expression through snail-driven activation of Wnt pathway in lung cancer cells
- in-vitro, Lung, H1299 - in-vitro, Lung, A549 - in-vitro, Lung, H460
PD-L1↑, Snail↑, E-cadherin↓, N-cadherin↑, Fibronectin↑, Vim↑, Axin2↓,
3078- RES,    The Effects of Resveratrol on Prostate Cancer through Targeting the Tumor Microenvironment
- Review, Pca, NA
*ROS↓, ROS↑, DNAdam↑, Apoptosis↑, Hif1a↑, Casp3↑, Casp9↑, Cyt‑c↑, Dose↝, MMPs↓, MMP2↓, MMP9↓, EMT↓, E-cadherin↑, N-cadherin↓, AR↓,
4663- RES,    Exploring resveratrol’s inhibitory potential on lung cancer stem cells: a scoping review of mechanistic pathways across cancer models
- Review, Var, NA
*antiOx↑, *Inflam↓, *chemoPv↑, CSCs↓, Wnt↓, β-catenin/ZEB1↓, NOTCH↓, PI3K↓, Akt↓, mTOR↓, GSK‐3β↝, Snail↓, HH↓, p‑GSK‐3β↓, N-cadherin↓, EMT↓, CD133↓, CD44↓, ALDH1A1↓, OCT4↓, SOX4↓, Shh↓, Smo↓, Gli1↓, GLI2↓,
1748- RosA,    The Role of Rosmarinic Acid in Cancer Prevention and Therapy: Mechanisms of Antioxidant and Anticancer Activity
- Review, Var, NA
AntiCan↑, *BioAv↝, *CardioT↓, *Iron↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *NRF2↑, MARK4↓, MMP9↓, TumCCA↑, Bcl-2↓, BAX↑, Apoptosis↑, E-cadherin↑, N-cadherin↓, Vim↓, Gli1↓, HDAC2↓, Warburg↓, Hif1a↓, miR-155↓, p‑PI3K↑, ROS↑, *IronCh↑,
1745- RosA,    Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications
- Review, Var, NA - Review, AD, NA
ChemoSideEff↓, ChemoSen↑, antiOx↑, MMP2↓, MMP9↓, p‑AMPK↑, DNMTs↓, tumCV↓, COX2/PTGS2↓, E-cadherin↑, Vim↓, N-cadherin↓, EMT↓, Casp3↑, Casp9↓, ROS↓, GSH↑, ERK↓, Akt↓, ROS↓, NF-kB↓, p‑IκB↓, p50↓, p65↓, neuroP↑, Dose↝,
1132- RT,    Rutin Promotes Proliferation and Orchestrates Epithelial–Mesenchymal Transition and Angiogenesis in MCF-7 and MDA-MB-231 Breast Cancer Cells
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7
Vim↑, N-cadherin↑, E-cadherin↓, TumCP↑, TumCMig↑, tumCV↑, MKI67↑,
5127- Sal,    Salinomycin repressed the epithelial–mesenchymal transition of epithelial ovarian cancer cells via downregulating Wnt/β-catenin pathway
- in-vitro, Ovarian, NA
TumCI↓, E-cadherin↑, N-cadherin↓, Vim↓, Wnt↓, β-catenin/ZEB1↓, TumCP↓, TumCMig↓, EMT↓,
1136- SFN,    Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells
- in-vitro, Lung, NA - in-vivo, NA, NA
TumCMig↓, E-cadherin↑, ZO-1↑, N-cadherin↓, Snail↓, ERK5↑, EMT↓,
1726- SFN,    Sulforaphane: A Broccoli Bioactive Phytocompound with Cancer Preventive Potential
- Review, Var, NA
Dose↝, eff↝, IL1β↓, IL6↓, IL12↓, TNF-α↓, COX2/PTGS2↓, CXCR4↓, MPO↓, HSP70/HSPA5↓, HSP90↓, VCAM-1↓, IKKα↓, NF-kB↓, HO-1↑, Casp3↑, Casp7↑, Casp8↑, Casp9↑, cl‑PARP↑, Cyt‑c↑, Diablo↑, CHOP/DDIT3↑, survivin↓, XIAP↓, p38↑, Fas↑, PUMA↑, VEGF↓, Hif1a↓, Twist↓, Zeb1↓, Vim↓, MMP2↓, MMP9↓, E-cadherin↑, N-cadherin↓, Snail↓, CD44↓, cycD1/CCND1↓, cycA1/CCNA1↓, CycB/CCNB1↓, cycE/CCNE↓, CDK4↓, CDK6↓, p50↓, P53↑, P21↑, GSH↑, SOD↑, GSTs↑, mTOR↓, Akt↓, PI3K↓, β-catenin/ZEB1↓, IGF-1↓, cMyc↓, CSCs↓,
3301- SIL,    Critical review of therapeutic potential of silymarin in cancer: A bioactive polyphenolic flavonoid
- Review, Var, NA
Inflam↓, TumCCA↑, Apoptosis↓, TumMeta↓, TumCG↓, angioG↓, chemoP↑, radioP↑, p‑ERK↓, p‑p38↓, p‑JNK↓, P53↑, Bcl-2↓, Bcl-xL↓, TGF-β↓, MMP2↓, MMP9↓, E-cadherin↑, Wnt↓, Vim↓, VEGF↓, IL6↓, STAT3↓, *ROS↓, IL1β↓, PGE2↓, CDK1↓, CycB/CCNB1↓, survivin↓, Mcl-1↓, Casp3↑, Casp9↑, cMyc↓, COX2/PTGS2↓, Hif1a↓, CXCR4↓, CSCs↓, EMT↓, N-cadherin↓, PCNA↓, cycD1/CCND1↓, ROS↑, Synergy↑, Synergy↑, Synergy↑, HER2/EBBR2↓,
3296- SIL,    Silibinin induces oral cancer cell apoptosis and reactive oxygen species generation by activating the JNK/c-Jun pathway
- in-vitro, Oral, Ca9-22 - in-vivo, Oral, YD10B
TumCP↓, TumCCA↑, ROS↑, SOD1↓, SOD2↓, *JNK↑, toxicity?, TumCMig↓, TumCI↓, N-cadherin↓, Vim↓, E-cadherin↑, EMT↓, P53↑, cl‑Casp3↑, cl‑PARP↑, BAX↑, Bcl-2↓, SOD↓,
3048- SK,    Shikonin inhibits triple-negative breast cancer-cell metastasis by reversing the epithelial-to-mesenchymal transition via glycogen synthase kinase 3β-regulated suppression of β-catenin signaling
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, 4T1 - in-vitro, Nor, MCF12A - in-vivo, NA, NA
tumCV↓, selectivity↑, EMT↓, TumCMig↓, TumCI↓, E-cadherin↑, N-cadherin↓, Vim↓, Snail↓, β-catenin/ZEB1↓, GSK‐3β↑,
5080- SSE,    Sodium Selenite Regulates the Proliferation and Apoptosis of Gastric Cancer Cells by Suppressing the Expression of LncRNA HOXB-AS1
- in-vitro, GC, HGC27 - in-vitro, GC, NCI-N87
AntiTum↑, HOXB-AS1↓, TumCP↓, TumCI↓, Apoptosis↑, BAD↓, Bcl-2↓, cl‑Casp3↑, MMP2↓, E-cadherin↑, N-cadherin↓, ROS↑, NF-kB↓,
6436- T4O,    Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression
- in-vitro, Melanoma, A431
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, EMT↓, AntiTum↑, cal2↑, cl‑β-catenin/ZEB1↑, cl‑Casp12↑, Bcl-2↓, cycD1/CCND1↓, CDK2↓, BAX↑, TumCCA↑, selectivity↑, N-cadherin↓, E-cadherin↑, Ki-67↓, PCNA↑,
1137- Taur,    Taurine Attenuates Epithelial-Mesenchymal Transition-Related Genes in Human Prostate Cancer Cells
- in-vitro, Pca, NA
N-cadherin↓, Twist↓, Zeb1↓, Snail↓, Vim↓, E-cadherin↑,
1935- TQ,    Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis
- Review, OS, NA
Apoptosis↑, TumCCA↑, angioG↓, TumMeta↓, ROS↑, P53↑, Twist↓, E-cadherin↑, N-cadherin↓, NF-kB↓, IL8↓, XIAP↓, Bcl-2↓, STAT3↓, MAPK↓, PI3K↓, Akt↓, ERK↓, MMP2↓, MMP9↓, *ROS↓, HO-1↑, selectivity↑, TumCG↓,
3422- TQ,    Thymoquinone, as a Novel Therapeutic Candidate of Cancers
- Review, Var, NA
selectivity↑, P53↑, PTEN↑, NF-kB↓, PPARγ↓, cMyc↓, Casp↑, *BioAv↓, CompStab↝, Synergy↑, survivin↓, Bcl-xL↓, Bcl-2↓, Akt↓, BAX↑, cl‑PARP↑, CXCR4↓, MMP9↓, VEGFR2/KDR/Flk1↓, Ki-67↓, COX2/PTGS2↓, JAK2↓, cSrc↓, Apoptosis↑, p‑STAT3↓, cycD1/CCND1↓, Casp3↑, Casp7↑, Casp9↑, N-cadherin↓, Vim↓, Twist↓, E-cadherin↑, ChemoSen↑, Synergy↑, EMT↓, ROS↑, DNMT1↓, Synergy↑, EZH2↓, hepatoP↑, Zeb1↓, RadioS↑, HDAC↓, HDAC1↓, HDAC2↓, HDAC3↓, *NAD↑, *SIRT1↑, SIRT1↓, *Inflam↓, *CRP↓, *TNF-α↓, *IL6↓, *IL1β↓, *Synergy↑, *MDA↓, *NO↓, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, PI3K↓, mTOR↓,
3427- TQ,    Chemopreventive and Anticancer Effects of Thymoquinone: Cellular and Molecular Targets
- in-vitro, Var, NA
ROS⇅, Fas↑, DR5↑, TRAIL↑, Casp3↑, Casp8↑, Casp9↑, P53↑, mTOR↓, Bcl-2↓, BID↓, CXCR4↓, JNK↑, p38↑, MAPK↑, LC3II↑, ATG7↑, Beclin-1/ATG6↑, AMPK↑, PPARγ↑, eIF2α↓, P70S6K↓, VEGF↓, ERK↓, NF-kB↓, XIAP↓, survivin↓, p65↓, DLC1↑, FOXO↑, TET2↑, CYP1B1↑, UHRF1↓, DNMT1↓, HDAC1↓, IL2↑, IL1↓, IL6↓, IL10↓, IL12↓, TNF-α↓, iNOS↓, COX2/PTGS2↓, 5LO↓, AP-1↓, PI3K↓, Akt↓, cMET↓, VEGFR2/KDR/Flk1↓, CXCL1↓, ITGA5↓, Wnt↓, β-catenin/ZEB1↓, GSK‐3β↓, Myc↓, cycD1/CCND1↓, N-cadherin↓, Snail↓, Slug↓, Vim↓, Twist↓, Zeb1↓, MMP2↓, MMP7↓, MMP9↓, JAK2↓, STAT3↓, NOTCH↓, cycA1/CCNA1↓, CDK2↓, CDK4↓, CDK6↓, CDC2↓, CDC25↓, Mcl-1↓, E2Fs↓, p16↑, p27/CDKN1B↑, P21↑, ChemoSen↑,
3431- TQ,    PI3K-AKT Pathway Modulation by Thymoquinone Limits Tumor Growth and Glycolytic Metabolism in Colorectal Cancer
- in-vitro, CRC, HCT116 - in-vitro, CRC, SW48
Glycolysis↓, Warburg↓, HK2↓, ATP↓, NADPH↓, PI3K↓, Akt↓, TumCP↓, E-cadherin↑, N-cadherin↓, Hif1a↓, PKM2↓, GlucoseCon↓, lactateProd↓, EMT↓,
1139- UA,    Ursolic acid inhibits epithelial-mesenchymal transition by suppressing the expression of astrocyte-elevated gene-1 in human nonsmall cell lung cancer A549 cells
- in-vitro, Lung, A549
TumMeta↓, AEG1↓, E-cadherin↑, N-cadherin↓, Vim↓, EMT↓,
5022- UA,    Ursolic Acid’s Alluring Journey: One Triterpenoid vs. Cancer Hallmarks
- Review, Var, NA
TumCP↓, Apoptosis↑, angioG↑, TumMeta↓, BioAv↓, Hif1a↓, Glycolysis↓, mitResp↓, Akt↓, MAPK↓, ERK↓, mTOR↓, P53↑, P21↑, E2Fs↑, STAT3↓, MMP↓, NLRP3↓, iNOS↓, CHK1↓, Chk2↓, BRCA1↓, E-cadherin↑, N-cadherin↓, Casp↑, p62↓, LC3II↑, Vim↓, ROS↑, CSCs↓, DNAdam↑, GutMicro↑, VEGF↓,
4856- Uro,    Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro
- in-vitro, NPC, CNE1 - in-vitro, NPC, CNE2
Apoptosis↑, MMP↓, ROS↑, E-cadherin↑, BAX↑, cl‑Casp3↑, PARP↑, MMP2↓, MMP9↓, N-cadherin↓, Vim↓, Snail↓, eff↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓,
4838- Uro,    The Therapeutic Potential of Urolithin A for Cancer Treatment and Prevention
- Review, Var, NA
BioAv↑, Inflam↓, IL6↓, IL1β↓, NOS2↓, p53 Wildtype↑, MDM2↑, Snail↓, E-cadherin↑, N-cadherin↓, Vim↓, NF-kB↓, mTOR↓, p‑Akt↓, selectivity↑, EMT↓,
4844- Uro,    Urolithin A Inhibits Epithelial–Mesenchymal Transition in Lung Cancer Cells via P53-Mdm2-Snail Pathway
- in-vitro, Lung, A549 - in-vitro, Lung, H460
TumCMig↓, TumCI↓, EMT↓, Snail↓, MDM2↑, P53↑, E-cadherin↑, N-cadherin↓, Vim↓,
1820- VitK3,    Vitamin K3 (menadione) suppresses epithelial-mesenchymal-transition and Wnt signaling pathway in human colorectal cancer cells
- in-vitro, CRC, SW480 - in-vitro, CRC, SW-620
selectivity↑, TumCI↓, TumCMig↓, EMT↓, E-cadherin↑, ZO-1↑, N-cadherin↓, Vim↓, Zeb1↓, MMP2↓, MMP9↓, TOPflash↓, β-catenin/ZEB1↓, p300↓, cycD1/CCND1↓, TumCCA↑,

Showing Research Papers: 101 to 138 of 138
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 138

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 3,   Catalase↓, 4,   Copper↑, 1,   ENOX2↓, 1,   GPx↓, 2,   GPx4↓, 3,   GSH↓, 10,   GSH↑, 2,   GSR↓, 1,   GSR↑, 1,   GSTs↓, 2,   GSTs↑, 1,   H2O2↑, 1,   HO-1↓, 4,   HO-1↑, 7,   Iron↑, 1,   lipid-P↑, 3,   MDA↑, 1,   MPO↓, 1,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 7,   NRF2↑, 6,   p‑NRF2↓, 1,   ROS↓, 8,   ROS↑, 50,   ROS⇅, 1,   ROS↝, 1,   i-ROS↑, 1,   mt-ROS↑, 2,   SOD↓, 7,   SOD↑, 3,   SOD1↓, 1,   SOD1↑, 1,   SOD2↓, 2,   SOD2↑, 1,   Trx1↑, 1,   TrxR↓, 2,   VitC↓, 1,   VitE↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 6,   CDC25↓, 2,   compI↓, 1,   compIII↓, 1,   compV↓, 1,   compV↓, 1,   EGF↓, 1,   ETC↓, 1,   Insulin↓, 1,   MFN2↓, 1,   mitResp↓, 4,   MKK7↓, 1,   mtDam↑, 7,   OCR↓, 2,   OXPHOS↓, 2,   PDH↓, 1,   PINK1↑, 2,   SIRT3↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   5LO↓, 1,   ACC↑, 2,   ACC-α↓, 1,   ACC1↓, 1,   ACLY↓, 2,   AMPK↑, 8,   p‑AMPK↑, 2,   ATP↓, 2,   CAIX/CA9↓, 1,   ECAR↓, 1,   ENO1↓, 1,   FASN↓, 3,   glucose↝, 1,   GlucoseCon↓, 2,   Glycolysis↓, 11,   GSK‐3β↓, 3,   GSK‐3β↑, 2,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 6,   HK1↓, 1,   HK2↓, 7,   lactateProd↓, 3,   LDHA↓, 4,   lipidLev↓, 1,   lipoGen↓, 2,   NADPH↓, 2,   NADPH↑, 1,   PDK1 / PDPK1↓, 2,   p‑PDK1 / PDPK1↓, 1,   PKM2↓, 4,   RARα↓, 1,   RARβ↑, 1,   RARγ↑, 1,   SIRT1↓, 4,   SIRT1↑, 1,   SREBP1/SREBF1↓, 2,   Warburg↓, 3,  

Cell Death(tgid=5) ⓘ

AIF↑, 1,   APAF1↑, 2,   Apoptosis?, 1,   Apoptosis↓, 1,   Apoptosis↑, 43,   ASC↓, 1,   ASK1↑, 1,   BAD↓, 1,   BAD↑, 4,   Bak↑, 2,   BAX↑, 32,   Bax:Bcl2↑, 3,   Bcl-2↓, 38,   Bcl-xL↓, 5,   BID↓, 1,   BID↑, 1,   BIM↑, 6,   BNIP3↑, 1,   BOK↑, 1,   Casp↑, 6,   Casp1↓, 1,   cl‑Casp12↑, 2,   cl‑Casp12↝, 1,   Casp3↓, 1,   Casp3↑, 35,   cl‑Casp3↑, 12,   Casp7↑, 5,   cl‑Casp7↑, 1,   Casp8↑, 8,   cl‑Casp8↑, 2,   Casp9↓, 1,   Casp9↑, 23,   p‑Casp9↑, 1,   cl‑Casp9↑, 5,   proCasp9↓, 1,   CellShr↑, 1,   cFLIP↓, 2,   Cyt‑c↑, 26,   mt-Cyt‑c↓, 1,   Diablo↑, 5,   DR5↑, 8,   FADD↑, 2,   Fas↑, 8,   FasL↑, 1,   Ferroptosis↑, 3,   GSDMD↑, 1,   HEY1↓, 1,   IAP1↓, 2,   iNOS↓, 7,   Mcl-1?, 1,   Mcl-1↓, 9,   MDM2↓, 4,   MDM2↑, 2,   p‑MDM2↓, 1,   NAIP↓, 1,   p38↓, 1,   p38↑, 4,   p‑p38↓, 2,   p‑p38↑, 1,   PUMA↑, 1,   Pyro↑, 1,   survivin↓, 11,   TRAIL↑, 2,   TumCD↑, 4,   XIAP↓, 7,   YAP/TEAD↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 46,   Akt↑, 1,   p‑Akt↓, 16,   AKT1↓, 3,   Akt2↓, 1,   cMET↓, 2,   cSrc↓, 1,   EGFR↓, 12,   EGFR↑, 1,   p‑EGFR↓, 1,   ERK↓, 12,   p‑ERK↓, 7,   ERK5↑, 1,   HER2/EBBR2↓, 2,   p‑HER2/EBBR2↓, 1,   HGF/c-Met↓, 1,   IKKα↓, 4,   IKKα↑, 1,   p‑IκB↓, 1,   JAK↓, 1,   p‑JAK↓, 1,   JAK1↓, 1,   JAK2↓, 3,   p‑JAK2↓, 1,   p‑JAK3↓, 1,   JNK↑, 4,   p‑JNK↓, 1,   p‑JNK↑, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 9,   MAPK↑, 4,   p‑MAPK↓, 1,   MARK4↓, 1,   MEK↓, 1,   MKK4↓, 1,   mTOR↓, 26,   mTOR↑, 1,   p‑mTOR↓, 6,   p70S6↓, 1,   P70S6K↓, 2,   PDGFR-BB↓, 1,   PDGFRA↓, 1,   PI3K↓, 38,   p‑PI3K↓, 3,   p‑PI3K↑, 1,   PI3K/Akt↓, 1,   PKCδ↓, 1,   PTEN↓, 2,   PTEN↑, 6,   RAS↓, 2,   SHP1↑, 1,   Sp1/3/4↓, 3,   p‑Src↓, 1,   STAT↓, 2,   p‑STAT2↓, 1,   STAT3↓, 20,   p‑STAT3↓, 5,   p‑STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↓, 1,   ATF4↑, 6,   p‑ATF4↝, 1,   CBP↓, 1,   cJun↓, 4,   cMyc↓, 13,   p‑cMyc↑, 1,   DNMT1↓, 3,   DNMT1↑, 1,   DNMT3A↓, 1,   DNMTs↓, 2,   EZH2↓, 3,   FOXO↑, 1,   FOXO1↓, 2,   FOXO3↓, 1,   FOXO3↑, 3,   p‑FOXO3↓, 1,   FOXO4↓, 1,   H19↓, 1,   H3↓, 1,   H3↑, 1,   ac‑H3↑, 1,   H4↓, 1,   ac‑H4↑, 1,   HATs↓, 1,   HDAC↓, 4,   HDAC1↓, 3,   HDAC2↓, 2,   HDAC3↓, 1,   HES1↓, 1,   HOXB-AS1↓, 1,   JPT1/HN1↓, 1,   LINC01116↓, 1,   miR-107↑, 1,   miR-10b-5p↓, 1,   miR-139-5p↑, 2,   miR-140↑, 1,   miR-155↓, 2,   miR-182-5p↓, 1,   miR-19b↓, 1,   miR-200c↑, 1,   miR-21↓, 2,   miR-224↓, 1,   miR-29b↓, 1,   miR-301a-3p↓, 1,   miR-339-5p↝, 1,   miR-340↓, 1,   miR-34a↑, 1,   miR-34b-5p↑, 1,   miR-384↑, 2,   miR-422a↑, 1,   miR-592↑, 1,   Myc↓, 2,   OCT4↓, 11,   other↓, 1,   other↑, 1,   other↝, 2,   PAX2↓, 1,   SOX2↓, 6,   SOX4↓, 1,   tumCV↓, 9,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 8,   p‑CHOP/DDIT3↝, 1,   eIF2α↓, 1,   eIF2α↑, 2,   p‑eIF2α↑, 3,   p‑eIF2α↝, 1,   ER Stress↑, 12,   Erlin1↑, 1,   GRP78/BiP↑, 3,   HSP27↓, 2,   HSP70/HSPA5↓, 4,   HSP90↓, 4,   IRE1↑, 3,   PDI↑, 1,   PERK↑, 5,   p‑PERK↝, 1,   UPR↓, 1,   UPR↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG7↑, 1,   Beclin-1/ATG6↑, 5,   CTSB↓, 1,   CTSD↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3A↑, 2,   LC3B↑, 1,   LC3B-II↑, 1,   LC3II↑, 6,   MitoP↑, 1,   p62↓, 4,   PARK2↑, 2,   TumAuto↑, 7,  

DNA Damage & Repair(tgid=10) ⓘ

BRCA1↓, 1,   DFF45↓, 1,   DNAdam↑, 11,   DNAdam⇅, 1,   DNArepair↓, 2,   ERCC1↓, 1,   ERCC3↑, 1,   hTERT/TERT↓, 5,   p16↑, 1,   P53↑, 23,   p‑P53↑, 1,   ac‑P53↑, 1,   p53 Wildtype↑, 1,   PARP↑, 6,   cl‑PARP↑, 17,   PARP1↑, 2,   cl‑PARP1↑, 1,   PCNA↓, 15,   PCNA↑, 1,   RAD51↓, 1,   Telomerase↓, 3,   TOP1↓, 1,   TOP2↓, 3,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↑, 4,   γH2AX↝, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 6,   CDK2↓, 15,   CDK2↑, 1,   CDK4↓, 12,   CDK4/6↓, 1,   CDK6↓, 5,   CHK1↓, 2,   p‑CHK1↑, 1,   Chk2↓, 2,   Cyc↓, 1,   cycA1/CCNA1↓, 4,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 10,   cycD1/CCND1↓, 21,   cycE/CCNE↓, 5,   E2Fs↓, 1,   E2Fs↑, 1,   Ki-67↓, 11,   MKI67↑, 1,   P21↓, 1,   P21↑, 13,   p27/CDKN1B↑, 5,   p‑pRB↓, 1,   RB1↓, 1,   p‑RB1↓, 2,   Securin↓, 2,   TAp63α↑, 1,   TumCCA↓, 2,   TumCCA↑, 42,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 2,   ALDH1A1↓, 2,   AXIN1↑, 1,   Axin2↓, 1,   BMI1↓, 2,   BMPs↑, 1,   CD133↓, 6,   CD34↓, 1,   CDX2↓, 1,   cFos↓, 4,   cFos↑, 1,   CSCs↓, 16,   CSCs↑, 1,   CSCsMark↓, 1,   Diff↑, 1,   EIF4E↓, 1,   Gli1↓, 6,   HH↓, 5,   IGF-1↓, 1,   Ki-67↓, 11,   Let-7↑, 1,   LRP6↓, 1,   p‑LRP6↓, 1,   mTORC1↓, 1,   Nanog↓, 6,   NICD↓, 1,   NOTCH↓, 9,   NOTCH1↓, 4,   NOTCH1↑, 1,   NOTCH3↓, 1,   p300↓, 2,   Piezo1↑, 1,   Pirin↓, 1,   Shh↓, 3,   Smo↓, 3,   p‑STAT1↓, 1,   TAZ↓, 1,   TOPflash↓, 1,   TumCG↓, 26,   TumCG↑, 2,   TumCP?, 1,   TumCP↓, 42,   TumCP↑, 4,   Wnt↓, 17,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

ACTA2↓, 1,   AEG1↓, 2,   AntiAg↓, 1,   AP-1↓, 2,   AXL↓, 1,   Ca+2↑, 11,   i-Ca+2↑, 1,   CAFs/TAFs↓, 1,   cal2↑, 1,   Cal9↑, 1,   Cdc42↓, 1,   Cofilin↓, 1,   DLC1↑, 1,   E-cadherin↓, 9,   E-cadherin↑, 103,   E-cadherin↝, 1,   EMT↓, 90,   EMT↑, 1,   EMT↝, 1,   EpCAM↓, 1,   F-actin↓, 1,   FAK↓, 2,   p‑FAK↓, 1,   fascin↓, 1,   Fibronectin↓, 7,   Fibronectin↑, 1,   GLI2↓, 1,   ITGA5↓, 1,   ITGB1↓, 1,   MALAT1↓, 1,   MET↓, 2,   MET↑, 1,   p‑MET↓, 1,   MMP1↓, 2,   MMP13↓, 1,   MMP15↓, 1,   MMP16↓, 2,   MMP2↓, 51,   MMP3↓, 6,   MMP7↓, 2,   MMP9↓, 51,   MMPs↓, 9,   N-cadherin?, 1,   N-cadherin↓, 130,   N-cadherin↑, 3,   N-cadherin↝, 1,   p‑pax↓, 1,   PIR↓, 1,   Rac1↓, 1,   Rho↓, 2,   ROCK1↓, 3,   Sharpin↓, 1,   Slug?, 1,   Slug↓, 16,   Smad1↓, 2,   p‑SMAD2↓, 5,   SMAD3↓, 1,   p‑SMAD3↓, 5,   Snail?, 1,   Snail↓, 49,   Snail↑, 1,   TET1↑, 1,   TGF-β↓, 5,   TGF-β↑, 1,   TGF-β1↓, 1,   TIMP1↓, 1,   TIMP1↑, 3,   TIMP2↓, 2,   TIMP2↑, 3,   TIMP3↑, 1,   TSP-1↑, 1,   TumCA↓, 1,   TumCI?, 2,   TumCI↓, 59,   TumCMig?, 1,   TumCMig↓, 57,   TumCMig↑, 1,   TumMeta↓, 31,   TumMeta↑, 1,   Twist↓, 19,   Tyro3↓, 1,   uPA↓, 8,   uPAR↓, 1,   Vim↓, 77,   Vim↑, 3,   Zeb1↓, 15,   ZEB2↓, 3,   α-SMA↓, 1,   β-catenin/ZEB1↓, 31,   cl‑β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 20,   angioG↑, 1,   CD31/PECAM-1↓, 2,   eNOS↓, 1,   HIF-1↓, 3,   Hif1a↓, 17,   Hif1a↑, 1,   NO↓, 1,   NO↑, 1,   NO↝, 1,   VCAM-1↓, 2,   VEGF↓, 30,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 6,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   CLDN1↓, 3,   CLDN2↓, 1,   CLDN7↑, 1,   MMP↓, 23,   MPT↑, 1,   ZO-1↓, 1,   ZO-1↑, 8,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD44↓, 8,   COX2/PTGS2↓, 19,   CXCL1↓, 1,   CXCL12↓, 1,   CXCR4↓, 7,   Eos↑, 1,   FOXP3↑, 1,   Gal-3↓, 1,   HMGB1↓, 2,   ICAM-1↓, 1,   IFN-γ↓, 1,   IL1↓, 3,   IL10↓, 2,   IL12↓, 2,   IL18↓, 1,   IL1β↓, 7,   IL2↑, 2,   IL6↓, 15,   IL8↓, 5,   Imm↑, 3,   Imm↝, 1,   Inflam↓, 5,   MCP1/CCL2↓, 1,   MIP-1β↑, 1,   mPGES-1↓, 1,   Neut↑, 1,   NF-kB↓, 32,   NF-kB↑, 1,   p‑NF-kB↓, 1,   p‑NF-kB↑, 1,   NK cell↑, 2,   NLRP3↓, 3,   p50↓, 2,   p65↓, 4,   p‑p65↓, 2,   PD-1↓, 1,   PD-L1↓, 2,   PD-L1↑, 1,   PGE2↓, 7,   PSA↓, 2,   TCF↑, 1,   TNF-α↓, 11,  

Synaptic & Neurotransmission(tgid=18) ⓘ

PTN↓, 1,  

Protein Aggregation(tgid=19) ⓘ

PSEN1/PS1↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 4,   ER-α36↓, 1,   FGF21↓, 1,   PPARα↑, 1,   PPARγ↓, 3,   PPARγ↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 6,   BioAv↑, 5,   BioAv↝, 1,   ChemoSen↓, 1,   ChemoSen↑, 34,   CompStab↝, 2,   CYP1A1↓, 1,   CYP1B1↑, 1,   Dose↑, 2,   Dose↝, 14,   Dose∅, 2,   eff↓, 4,   eff↑, 7,   eff↝, 2,   Half-Life↓, 1,   Half-Life↝, 1,   MDR1↓, 3,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 2,   RadioS↑, 10,   selectivity↑, 15,   Synergy↑, 34,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   AR↓, 4,   BRCA1↓, 1,   CEA↓, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 12,   EGFR↑, 1,   p‑EGFR↓, 1,   EZH2↓, 3,   HER2/EBBR2↓, 2,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 5,   IL6↓, 15,   LDH↓, 2,   LDH↑, 1,   Myc↓, 2,   NOS2↓, 1,   NSE↓, 1,   PD-L1↓, 2,   PD-L1↑, 1,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 9,   AntiTum↑, 8,   cachexia↓, 2,   cardioP↑, 2,   chemoP?, 1,   chemoP↑, 5,   chemoPv↑, 4,   ChemoSideEff↓, 1,   fatigue↓, 1,   hepatoP↑, 2,   neuroP↑, 2,   OS↑, 6,   Pin1↓, 1,   QoL↑, 1,   radioP↑, 2,   RenoP↑, 1,   toxicity?, 1,   toxicity↓, 4,   toxicity↑, 1,   toxicity↝, 2,   TumVol↓, 7,   TumW↓, 4,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 1,   AntiViral↑, 1,   Bacteria↓, 2,   GutMicro↑, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 652

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 17,   Catalase↑, 10,   GPx↑, 8,   GSH↑, 7,   GSR↑, 2,   GSTs↑, 3,   HO-1↑, 6,   Iron↓, 1,   lipid-P↓, 10,   MDA↓, 5,   NQO1↑, 1,   NRF2↑, 11,   Prx↑, 1,   ROS↓, 20,   SOD↑, 11,   SOD2↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↓, 1,   ALAT↓, 2,   AMPK↑, 2,   DGAT1↓, 1,   FASN↓, 1,   glucose↓, 1,   LDHA↑, 1,   lipidLev↓, 1,   NAD↑, 1,   NH3↓, 1,   SIRT1↑, 2,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 2,   BAX↓, 1,   Casp↓, 1,   Casp3?, 1,   Casp3↓, 2,   Cyt‑c↓, 1,   Ferroptosis↓, 1,   iNOS↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 2,   ERK↓, 1,   ERK↑, 1,   p‑ERK↑, 1,   IκB?, 1,   JNK↓, 1,   JNK↑, 1,   MAPK↓, 1,   mTOR↓, 1,   mTOR↑, 1,   P70S6K↓, 1,   PI3K↓, 1,   PI3K↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   p‑cMyc↑, 1,   HDAC↓, 1,   RUNX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,   HSP90↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 2,   p62↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   Diff↝, 1,  

Migration(tgid=13) ⓘ

Ca+2↓, 1,   Ca+2↝, 1,   cal2↓, 1,   COL1↑, 1,   E-cadherin↑, 1,   F-actin↓, 1,   N-cadherin↓, 1,   N-cadherin↑, 2,   Snail↓, 1,   TregCell↑, 1,   TumCMig↓, 1,   Vim↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   CD31/PECAM-1↑, 2,   Hif1a↓, 1,   NO↓, 2,   VEGF↑, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   IBI↑, 2,   MMP↑, 2,   TRPC1↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 4,   ICAM-1↓, 1,   IL10↓, 1,   IL10↑, 1,   IL18↓, 1,   IL1β↓, 4,   IL2↓, 1,   IL6↓, 6,   IL8↓, 1,   Inflam↓, 16,   NF-kB↓, 4,   NK cell↑, 1,   PGE2↓, 2,   RAGE↓, 1,   SOCS-3↓, 1,   TLR4↓, 1,   TNF-α↓, 8,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   AChE↓, 3,   MAOB↓, 1,   TPH1↓, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   APP↓, 1,   Aβ↓, 5,   BACE/β-secretase↓, 1,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   PPARα↝, 1,   p‑PPARγ↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 8,   BioAv↑, 3,   BioAv↝, 5,   CYP2E1↓, 1,   Dose↑, 1,   Dose↝, 1,   eff↑, 1,   Half-Life↓, 1,   Half-Life↝, 4,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALP↓, 1,   AST↓, 2,   BP↓, 1,   CRP↓, 1,   IL6↓, 6,   LDH↓, 2,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   antiAll↑, 4,   AntiArt↑, 1,   AntiCan↑, 2,   AntiDiabetic↑, 3,   AntiTum↑, 2,   cardioP↑, 5,   CardioT↓, 1,   chemoP↑, 1,   chemoPv↑, 3,   cognitive↑, 4,   hepatoP↑, 3,   Learn↑, 1,   memory↑, 3,   Mucositis↓, 1,   neuroP↑, 9,   Obesity↓, 1,   RenoP↑, 1,   Stroke↓, 2,   toxicity↓, 6,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 2,  
Total Targets: 152

Scientific Paper Hit Count for: N-cadherin, N-cadherin
8 Curcumin
8 Luteolin
7 Resveratrol
5 Berberine
5 Fisetin
5 Quercetin
4 Honokiol
4 Morin
4 Thymoquinone
3 Artemisinin
3 Baicalein
3 Inositol
3 phytic acid, Inositol hexakisphosphate
3 Isorhamnetin
3 Sulforaphane (mainly Broccoli)
3 Urolithin
2 Astragalus
2 Ashwagandha(Withaferin A)
2 Betulinic acid
2 Centella asiatica / Gotu kola → asiaticoside
2 Chlorogenic acid
2 Emodin
2 Grapeseed extract
2 Isoliquiritigenin
2 Juglone
2 Kaempferol
2 Matrine
2 Melatonin
2 Piperlongumine
2 Rosmarinic acid
2 Silymarin (Milk Thistle) silibinin
2 Ursolic acid
1 3-bromopyruvate
1 Allicin (mainly Garlic)
1 Cisplatin
1 Apigenin (mainly Parsley)
1 Astaxanthin
1 Baicalin
1 Biochanin A
1 Butyrate
1 Capsaicin
1 Carvacrol
1 Cannabidiol
1 Chrysin
1 Crocetin
1 Oxaliplatin
1 Cyclopamine
1 Diindolylmethane
1 Eurycomanone
1 Eugenol
1 Evodiamine
1 Sorafenib (brand name Nexavar)
1 Fucoidan
1 Garcinol
1 Ginkgolide B
1 Ginger/6-Shogaol/Gingerol
1 Ginkgetin
1 Proanthocyanidins
1 HydroxyTyrosol
1 capecitabine
1 Isothiocyanates
1 L-Theanine
1 Laetrile B17 Amygdalin
1 Licorice
1 Lycopene
1 Magnolol
1 Oroxylin-A
1 Phenylbutyrate
1 Phenethyl isothiocyanate
1 Phycocyanin
1 Piperine
1 Rutin
1 salinomycin
1 Shikonin
1 Selenite (Sodium)
1 Terpinen-4-ol / Tea Tree Oil
1 Taurine
1 VitK3,menadione
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:355  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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