cognitive Cancer Research Results

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Scientific Papers found: Click to Expand⟱
3697- BM,    Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies
- Review, AD, NA
*ROS↓, *cognitive↑, *memory↑, *BBB↑, *P-gp↓, *CYP3A2↓,
3692- BM,    Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *Aβ↓, *cognitive↑,
3691- BM,    Effects of a Standardized Bacopa monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly: A Randomized, Double-Blind, Placebo-Controlled Trial
- Study, Nor, NA
*cognitive↑, *memory↑, *BP∅,
3690- BM,    Neurocognitive Effect of Nootropic Drug Brahmi (Bacopa monnieri) in Alzheimer's Disease
- Review, AD, NA
*ROS↓, *5LO↓, *lipid-P↓, *GPx↑, *IronCh↑, *neuroP↑, *AChE↓, *memory↑, *toxicity↓, *SOD↑, *Catalase↑, *cognitive↑, *ChAT↑, *Ach↑, *BP↓,
5663- BNL,    Osthole/borneol thermosensitive gel via intranasal administration enhances intracerebral bioavailability to improve cognitive impairment in APP/PS1 transgenic mice
- in-vivo, AD, NA
*ZO-1↓, *cl‑Casp3↓, *Bax:Bcl2↓, *MDA↓, *Apoptosis↓, *Aβ↓, *BACE↓, *cognitive↑, *BioAv↑, memory↑, P-gp↓, BioEnh↑,
3518- Bor,    Boron Report
- Review, Var, NA - Review, AD, NA
Risk↓, serineP↓, PSA↓, TumVol↓, IGF-1↓, *Mag↑, *Calcium↑, *VitD↑, *COX2↓, *5LO↓, *PGE2↓, *NF-kB↓, *cognitive↑,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
760- Bor,    Therapeutic Efficacy of Boric Acid Treatment on Brain Tissue and Cognitive Functions in Rats with Experimental Alzheimer’s Disease
- in-vivo, AD, NA
*memory↑, *ROS↓, *GSH↑, *Aβ↓, *Inflam↓, *MMP↑, *lipid-P↓, *Ca+2↓, *cognitive↑, *TOS↓,
2775- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
ROS↑, ER Stress↑, TumCG↓, Apoptosis↑, Inflam↓, ChemoSen↑, Casp↑, ERK↓, cl‑PARP↑, AR↓, cycD1/CCND1↓, VEGFR2↓, CXCR4↓, radioP↑, NF-kB↓, VEGF↓, P21↑, Wnt↓, β-catenin/ZEB1↓, Cyt‑c↑, MMP2↓, MMP1↓, MMP9↓, PI3K↓, MAPK↓, JNK↑, *5LO↓, *NRF2↑, *HO-1↑, *MDA↓, *SOD↑, *hepatoP↑, *ALAT↓, *AST↓, *LDH↑, *CRP↓, *COX2↓, *GSH↑, *ROS↓, *Imm↑, *Dose↝, *eff↑, *neuroP↑, *cognitive↑, *IL6↓, *TNF-α↓,
2768- Bos,    Boswellic acids as promising agents for the management of brain diseases
- Review, Var, NA - Review, AD, NA - Review, Park, NA
*neuroP↑, *ROS↓, *cognitive↓, TumCP↓, TumCMig↓, TumMeta↓, angioG↓, Apoptosis↑, *Inflam↓, IL1↓, IL2↓, IL4↓, IL6↓, TNF-α↓, P53↑, Akt↓, NF-kB↓, DNAdam↑, Casp↑, COX2↓, MMP9↓, CXCR4↓, VEGF↓, *SOD↑, *Catalase↑, *GPx↑, *NRF2↑,
2772- Bos,    Mechanistic role of boswellic acids in Alzheimer’s disease: Emphasis on anti-inflammatory properties
- Review, AD, NA
*neuroP↑, *Inflam↓, *AChE↓, *Choline↑, *NRF2↑, *NF-kB↑, *BBB↑, *BioAv↑, *Half-Life↓, *Dose↝, *PGE2↓, *ROS↓, *cognitive↑, *antiOx↑, 5LO↓, *TNF-α↓, *IL6↓, *HO-1↑,
6553- BSB,    Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms
- Review, Nor, NA
*ROS↓, *Inflam↓, *Inf↓, *neuroP↑, *RNS↓, *MDA↓, *GSH↑, *MPO↓, *SOD↑, *Catalase↑, *Bcl-2↑, *BAX↓, *P53↓, *APAF1↓, *Casp3↓, *Casp9↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2↓, *ERK↓, *JNK↓, *NF-kB↓, *p38↓, *cognitive↑, *BChE↓,
5756- CA,    Experimental Evidence of Caffeic Acid’s Neuroprotective Activity in Alzheimer’s Disease: In Vitro, In Vivo, and Delivery-Based Insights
- vitro+vivo, AD, NA
*neuroP↑, *antiOx↑, *Inflam↓, *AChE↓, *BChE↓, *cognitive↑, *ROS↓, *Aβ↓, *tau↓, eff↑,
3791- CA,    Caffeic Acid and Diseases—Mechanisms of Action
- Review, AD, NA
*memory↑, *cognitive↑, *p‑tau↓, *ROS↓, *Inflam↓, *NF-kB↓, *Casp3↓, *lipid-P↓, *AChE↓, *BChE↓, *GSK‐3β↓, *5LO↓, *BDNF↓, VEGF↓, HSP70/HSPA5↓,
4265- CA,    Potential applications of nanomedicine for treating Parkinson's disease
- Review, Park, NA
*NRF2↑, *ARE↑, *neuroP↑, *motorD↑, *cognitive↑, *SOD↑, *GSR↑, *NGF↑, *BDNF↑,
4267- Caff,    Caffeine‐mediated BDNF release regulates long‐term synaptic plasticity through activation of IRS2 signaling
- in-vivo, NA, NA
*cognitive↑, *memory↑, *Mood↑, *BDNF↑, *TrkB↑,
4161- Caff,    Chronic caffeine prevents changes in inhibitory avoidance memory and hippocampal BDNF immunocontent in middle-aged rats
- in-vivo, AD, NA
*BDNF↑, *cognitive↑, *memory↑,
5860- CAP,    Beneficial Effects of Capsaicin in Disorders of the Central Nervous System
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *memory↑, *Pain↓, *TRPV1↑, *Aβ↓, *tau↓, *cognitive↑, *Risk↓, *motorD↓, *ROS↓, *TNF-α↓, *IL1β↓, *eff↑, *Risk↓,
3854- CAP,    Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice
- in-vivo, AD, NA
*Aβ↓, *cognitive↑, *APP↓, *MMP-10↝, *p‑tau↓, *Inflam↓, *neuroP↑, *Risk↓, *TNF-α↓, *IFN-γ↓, *IL6↓, *PPARα↑,
3855- CAP,    Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice
- in-vivo, AD, NA
*Risk↓, *Aβ↓, *p‑tau↓, *Inflam↓, *neuroP↑, *cognitive↑, *ADAM10↑, *PPARα↑,
5908- CAR,    Carvacrol improves neurological function by inhibiting TRPM7-mediated BBB disruption and hemorrhage after TBI
- in-vivo, Nor, NA
*TRPM7↓, *BBB↑, *motorD↑, *cognitive↑, *Dose↝, MMPs↓,
5927- CAR,    Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer’s and Parkinson’s Diseases
- Review, AD, NA - Review, Park, NA
*memory↑, *cognitive↑, *ROS↓, *Inflam↓, *motorD↑, *toxicity↓, *TRPV3↑, *other↓, *antiOx↑, *LDL↓, *COX2↓, *PPARα↑, *NO↓, *AChE↓, *eff↑, *SOD↑, *Catalase↑, *neuroP↑, *BioAv↝, *BBB↑, *BioAv↑,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, asthmatic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *eff↑, *BChE↓, *CRP↓,
5925- CAR,    Neuroprotective effects of carvacrol against Alzheimer’s disease and other neurodegenerative diseases: A review
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AChE↓, *BBB↑, *cardioP↑, *neuroP↑, *memory↑, *TAC↑, *ROS↓, *lipid-P↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *cognitive↑, *IL1β↓, *COX2↓, *TNF-α↓, *TLR4↓, *BDNF↑, *PKCδ↑, *5LO↓, *TRPM7↓, *GSH↑, *other↑, *Ferroptosis↓, *GPx4↑,
3876- Carno,  Ex,    Swimming exercise versus L-carnosine supplementation for Alzheimer’s dementia in rats: implication of circulating and hippocampal FNDC5/irisin
- in-vivo, AD, NA
*cognitive↑, *neuroP↑,
3879- Carno,    Daily Carnosine and Anserine Supplementation Alters Verbal Episodic Memory and Resting State Network Connectivity in Healthy Elderly Adults
- Human, AD, NA
*memory↑, *cognitive↑,
3873- Carno,    Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice
- in-vivo, AD, NA
*ROS↓, *IronCh↑, *Aβ↓, *AntiAge↑, *lipid-P↓, *cognitive↑, *memory∅,
3880- Carno,    EFFECT OF ANSERINE/CARNOSINE SUPPLEMENTATION ON THE PREVENTION OF ALZHEIMER'S DISEASE IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT
- Trial, AD, NA
*cognitive↑, *other↑,
3881- Carno,    The Therapeutic Potential of Carnosine/Anserine Supplementation against Cognitive Decline: A Systematic Review with Meta-Analysis
- Review, AD, NA
*cognitive↑,
6638- Cen,    Prolonged Treatment with Centella asiatica Improves Memory, Reduces Amyloid-β Pathology, and Activates NRF2-Regulated Antioxidant Response Pathway in 5xFAD Mice
- in-vivo, AD, NA
*memory↑, *Aβ↓, *NRF2↑, *toxicity↓, *neuroP↑, *ROS↓, *mtDam↓, *cognitive↑, NQO1↑, HO-1↑,
6635- Cen,    Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers
- Trial, Nor, NA
*BioAv↝, *eff↑, *Choline↑, *memory↑, *cognitive↑, *neuroP↑, *BioAv↑,
6636- Cen,    Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial
- Trial, AD, NA
*cognitive↑, *NRF2↑, *Dose↝, *memory↑, *ROS↓, *mitResp↑, *neuroP↑, *Half-Life↝, *Half-Life↝, *Half-Life↝,
6637- Cen,    Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis
- Review, AD, NA
*cognitive∅, *Mood↑, *Anger↓, *Wound Healing↑, *Dose↝,
6639- Cen,    Centella asiatica Alters Metabolic Pathways Associated With Alzheimer’s Disease in the 5xFAD Mouse Model of ß-Amyloid Accumulation
- in-vivo, AD, NA
*cognitive↑, *mtDam↓, *ROS↓, *NAD↑, *BDNF↑, *memory↑,
6662- Cen,    Assessment report on Centella asiatica (L.) Urban, herba
- Review, Nor, NA
*cognitive↑, *Inflam↓, *AntiBio↑, *Imm↑, *antiOx↑, *Wound Healing↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSTs↑, *MDA↓, *lipid-P↓, *ROS↓, *memory↑, *GABA↑, *antiPs↑, *BioAv↝,
6659- Cen,    cognitive_impairment_MCI_and_other_common_age-related_clinical_problems">Effect of Centella asiatica on mild cognitive impairment (MCI) and other common age-related clinical problems
- Trial, AD, NA
*Dose↝, *cognitive↑, *Sleep↑,
6655- Cen,    Centella asiatica improves cognitive function and alters the hippocampal metabolome of aged Tg2576 and wild-type mice
- in-vivo, AD, NA
*cognitive↑, *Dose↝, *memory↑, *AChE∅, *mtDam↓, *antiOx↑,
6649- Cen,    Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action
- in-vivo, AD, NA
*eff↑, *memory↑, *NO↓, *cognitive↑, *AChE∅,
6650- Cen,    Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review
- Review, AD, NA
*BioAv↝, *BioAv↝, *MDA↓, *GSH↑, *SOD↑, *AChE↓, *memory↑, *Ki-67↑, *Catalase↑, *PI3K↑, *BDNF↑, *NGF↑, *ROS↓, *NRF2↑, *HO-1↑, *NQO1↑, *ATP↑, *OCR↑, *TNF-α↓, *PP2A↑, *GSK‐3β↓, *Bcl-2↑, *TrkB↑, *NOTCH1↑, *SOX2↑, *Nestin↑, *MDA↓, *MAOA↓, *MAOB↓, *GPx↑, *cognitive↑, *ROS↓, *neuroP↑, *glucose↓, *ALAT↓, *AST↓, *PFK↓, *Weight↓, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *cardioP↑, *GutMicro↑, *Sepsis↓, *BioAv↑,
6646- Cen,    Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke
- Trial, Stroke, NA
*eff↑, *memory↑, *cognitive↑, *AST∅, *ALAT∅, *AChE↓, *toxicity↓,
6018- CGA,    Chlorogenic acid: a review on its mechanisms of anti-inflammation, disease treatment, and related delivery systems
- Review, Var, NA - Review, RCC, NA
*BioAv↓, *Inflam↓, *TNF-α↓, *NO↓, *COX2↓, *PGE2↓, *NF-kB↓, *IL6↓, *IL1β↓, *TLR2↓, *MAPK↓, *NRF2↓, *HO-1↑, *NQO1↑, *cardioP↑, *neuroP↑, *SOD↑, *GSH↑, *ROS↓, *LDH↓, *MDA↓, *cognitive↑, *eff↑,
6017- CGA,    Therapeutic Potential of Chlorogenic Acid in Chemoresistance and Chemoprotection in Cancer Treatment
- Review, Var, NA
AntiCan↑, *chemoP↑, TNF-α↓, COX2↓, IL6↓, eff↑, PD-L1↓, *cognitive↓, *Aβ↓, *TAC↑, *SOD↑, *eff↑, *eff↑, ChemoSen↑, tumCV↓, Apoptosis↑, ERK↓, chemoP↑, *GPx↑, *GSTs↑, *GSH↑, *SOD↑, *Catalase↑, *ROS↓, *lipid-P↓, *MDA↓, *Casp3↓, *HO-1↓, cardioP↑, radioP↑,
6038- CGA,    Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices
- in-vivo, AD, NA - in-vivo, Stroke, NA
*eff↑, *other↓, *Risk↓, *cognitive↑, *neuroP↑, *antiOx↑,
6039- CGA,    Impact of coffee-derived chlorogenic acid on cognition: a systematic review and meta-analysis
- Review, AD, NA
*cognitive↑, *cognitive∅,
6040- CGA,    Protective effect of chlorogenic acid on cognitive impairment in rats with early Alzheimer's disease via Wnt signaling pathway
- in-vivo, AD, NA
*neuroP↑, *Dose↝, *GSK‐3β↓, *tau↓, *β-catenin/ZEB1↑, *Wnt↑, *memory↑, *cognitive↑, *NRF2↑, *ROS↓,
6041- CGA,    Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study
- Trial, AD, NA
*Dose↝, *memory↑, *Risk↓, *cognitive↑, *Aβ↓, *antiOx↓, *motorD↑,
6036- CGA,    Effect of Chlorogenic Acids on Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Trial
- Trial, Nor, NA
*motorD↑, *cognitive↑, *eff↑,
6035- CGA,    Effect of Chlorogenic Acids on Cognitive Function in Mild Cognitive Impairment: A Randomized Controlled Crossover Trial
- Trial, Nor, NA
*Dose↝, *cognitive↑, *Risk↓, *AChE↓, *ROS↓,
6034- CGA,    Effect and mechanism of chlorogenic acid on cognitive dysfunction in mice by lipopolysaccharide-induced neuroinflammation
- in-vivo, AD, NA
*cognitive↑, *TNF-α↓, *antiOx↑, *Inflam↓, *neuroP↑, *BBB↑, *eff↑, *memory↑, *AKT1↓, *MMP9↓, *MAPK↓,
6001- Chit,    Recent advances in engineering chitosan-based nanoplatforms in biotherapeutic multi-delivery for multi-targeted disease treatments: Promises and outlooks
- Review, Var, HepG2 - Review, AD, NA
TumVol↓, toxicity↓, Half-Life↑, eff↑, selectivity↑, Dose↝, *BDNF↑, *NRF2↑, *ROS↓, *neuroP↑, *memory↑, *cognitive↑, *Obesity↓,

Showing Research Papers: 101 to 150 of 515
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 515

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

HO-1↑, 1,   NQO1↑, 1,   ROS↑, 1,  

Cell Death(tgid=5)

Akt↓, 1,   Apoptosis↑, 4,   Casp↑, 2,   Cyt‑c↑, 1,   JNK↑, 1,   MAPK↓, 1,  

Transcription & Epigenetics(tgid=7)

tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8)

ER Stress↑, 1,   HSP70/HSPA5↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 1,   P53↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11)

Cyc↓, 1,   cycD1/CCND1↓, 1,   P21↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

ERK↓, 2,   HDAC↓, 1,   IGF-1↓, 2,   PI3K↓, 1,   TumCG↓, 1,   Wnt↓, 1,  

Migration(tgid=13)

5LO↓, 1,   MMP1↓, 1,   MMP2↓, 1,   MMP9↓, 2,   MMPs↓, 1,   serineP↓, 1,   TumCMig↓, 2,   TumCP↓, 1,   TumMeta↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 2,   HIF-1↓, 1,   VEGF↓, 3,   VEGFR2↓, 1,  

Barriers & Transport(tgid=15)

P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2↓, 2,   CXCR4↓, 2,   IL1↓, 1,   IL2↓, 1,   IL4↓, 1,   IL6↓, 2,   Inflam↓, 1,   NF-kB↓, 2,   PD-L1↓, 1,   PGE2↓, 1,   PSA↓, 2,   TNF-α↓, 2,  

Hormonal & Nuclear Receptors(tgid=20)

AR↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioEnh↑, 1,   ChemoSen↑, 2,   Dose↝, 1,   eff↑, 3,   Half-Life↑, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22)

AR↓, 1,   IL6↓, 2,   PD-L1↓, 1,   PSA↓, 2,  

Functional Outcomes(tgid=23)

AntiCan↑, 2,   cardioP↑, 1,   chemoP↑, 1,   memory↑, 1,   radioP↑, 2,   Risk↓, 2,   toxicity↓, 1,   TumVol↓, 3,  
Total Targets: 70

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

AntiBio↑, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↓, 1,   antiOx↑, 9,   ARE↑, 1,   Catalase↑, 9,   Ferroptosis↓, 1,   GPx↑, 6,   GPx4↑, 1,   GSH↑, 7,   GSR↑, 1,   GSTs↑, 2,   HO-1↓, 1,   HO-1↑, 4,   lipid-P↓, 7,   MDA↓, 9,   MPO↓, 1,   NQO1↑, 2,   NRF2↓, 1,   NRF2↑, 11,   RNS↓, 1,   ROS↓, 25,   SAM-e↑, 1,   SOD↑, 13,   TAC↑, 2,   TOS↓, 1,  

Metal & Cofactor Biology(tgid=2)

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3)

ATP↑, 2,   ATP↝, 1,   mitResp↑, 1,   MMP↑, 1,   mtDam↓, 3,   OCR↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

AKT1↓, 1,   ALAT↓, 2,   ALAT∅, 1,   CYP3A2↓, 1,   glucose↓, 1,   LDH↓, 1,   LDH↑, 1,   LDL↓, 1,   NAD↑, 1,   NAD↝, 1,   PFK↓, 1,   PPARα↑, 3,  

Cell Death(tgid=5)

APAF1↓, 1,   Apoptosis↓, 1,   BAX↓, 1,   Bax:Bcl2↓, 1,   Bcl-2↑, 2,   Casp3↓, 3,   cl‑Casp3↓, 1,   Casp9↓, 1,   Ferroptosis↓, 1,   iNOS↓, 1,   JNK↓, 1,   MAPK↓, 2,   p38↓, 1,   TRPV1↑, 1,  

Kinase & Signal Transduction(tgid=6)

TRPV3↑, 2,  

Transcription & Epigenetics(tgid=7)

Ach↑, 1,   other↓, 2,   other↑, 2,   other↝, 1,  

DNA Damage & Repair(tgid=10)

P53↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

Choline↑, 2,   ERK↓, 1,   GSK‐3β↓, 3,   Nestin↑, 1,   NOTCH1↑, 1,   PI3K↑, 1,   SOX2↑, 1,   TRPM7↓, 2,   Wnt↑, 1,  

Migration(tgid=13)

5LO↓, 6,   AntiAg↑, 1,   APP↓, 1,   Ca+2↓, 1,   Ca+2↑, 1,   Ca+2↝, 1,   Ki-67↑, 1,   MMP-10↝, 1,   MMP9↓, 1,   PKCδ↑, 1,   serineP↓, 1,   ZO-1↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14)

NO↓, 3,  

Barriers & Transport(tgid=15)

BBB↑, 6,   GastroP↑, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2↓, 7,   CRP↓, 2,   IFN-γ↓, 1,   IL1β↓, 4,   IL6↓, 5,   Imm↑, 2,   Inflam↓, 17,   NF-kB↓, 4,   NF-kB↑, 1,   PGE2↓, 3,   TLR2↓, 1,   TLR4↓, 1,   TNF-α↓, 10,   VitD↑, 2,  

Synaptic & Neurotransmission(tgid=18)

AChE↓, 10,   AChE∅, 2,   ADAM10↑, 1,   BChE↓, 4,   BDNF↓, 1,   BDNF↑, 7,   ChAT↑, 1,   GABA↑, 1,   MAOA↓, 1,   NGF↑, 2,   tau↓, 3,   p‑tau↓, 3,   TrkB↑, 2,  

Protein Aggregation(tgid=19)

Aβ↓, 11,   BACE↓, 1,   MAOB↓, 1,   PP2A↑, 1,  

Hormonal & Nuclear Receptors(tgid=20)

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,   BioAv↑, 6,   BioAv↝, 5,   Dose↑, 1,   Dose↝, 11,   eff↑, 14,   Half-Life↓, 1,   Half-Life↝, 3,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22)

ALAT↓, 2,   ALAT∅, 1,   AST↓, 2,   AST∅, 1,   BMD↑, 1,   BMPs↑, 1,   BP↓, 1,   BP∅, 1,   Calcium↑, 2,   CRP↓, 2,   GutMicro↑, 1,   hs-CRP↓, 1,   IL6↓, 5,   Ki-67↑, 1,   LDH↓, 1,   LDH↑, 1,   Mag↑, 2,   VitD↑, 2,  

Functional Outcomes(tgid=23)

Anger↓, 1,   AntiAge↑, 1,   AntiDiabetic↑, 1,   antiPs↑, 1,   cardioP↑, 5,   chemoP↑, 2,   chemoPv↑, 2,   ChemoSideEff↓, 1,   cognitive↓, 2,   cognitive↑, 47,   cognitive∅, 2,   hepatoP↑, 2,   memory↑, 25,   memory∅, 1,   Mood↑, 2,   motorD↓, 1,   motorD↑, 5,   neuroP↑, 25,   Obesity↓, 2,   Pain↓, 2,   Risk↓, 8,   Sleep↑, 1,   toxicity↓, 5,   Weight↓, 1,   Wound Healing↑, 3,  

Infection & Microbiome(tgid=24)

Diar↓, 1,   Inf↓, 1,   Sepsis↓, 1,  
Total Targets: 177

Scientific Paper Hit Count for: cognitive, cognitive
23 Vitamin B12
22 Magnetic Fields
21 Folic Acid, Vit B9
19 Alpha-Lipoic-Acid
18 Hydrogen Gas
15 Curcumin
14 Vitamin B6,pyridoxine
13 beta-carotene(VitA)
12 Choline
12 Phosphatidylserine
12 Urolithin
11 Exercise
11 Centella asiatica / Gotu kola → asiaticoside
11 Thymoquinone
10 Bacopa monnieri
10 Crocetin
9 Chlorogenic acid
9 Vitamin E
9 Resveratrol
9 Lutein
9 Zeaxanthin
9 MCToil
9 Quercetin
9 Vitamin D3
8 Anthocyanins
8 Aromatherapy
8 Berberine
8 Selenium NanoParticles
7 Ashwagandha(Withaferin A)
7 Huperzine A/Huperzia serrata
7 Magnetic Field Rotating
7 Rosmarinic acid
7 Salvia officinalis
6 Allicin (mainly Garlic)
6 Ginseng
6 Mushroom Lion’s Mane
6 EMF
6 Sulforaphane (mainly Broccoli)
6 Silymarin (Milk Thistle) silibinin
6 Silicic Acid
5 5-Hydroxytryptophan
5 Vitamin C (Ascorbic Acid)
5 Vitamin B3,Niacin
5 Carvacrol
5 Carnosine
5 EGCG (Epigallocatechin Gallate)
5 Rutin
5 Taurine
5 Vitamin K2
4 Acetyl-l-carnitine
4 Aluminum
4 Docosahexaenoic Acid
4 Ferulic acid
4 Lycopene
4 Spermidine
4 Vitamin B1/Thiamine
3 flavonoids
3 Baicalein
3 Boron
3 Boswellia (frankincense)
3 Capsaicin
3 Chocolate
3 Cinnamon
3 Coenzyme Q10
3 Galantamine
3 diet Short Term Fasting
3 Shilajit/Fulvic Acid
3 Honokiol
3 Moringa oleifera
3 nicotinamide adenine dinucleotide
3 Piperine
3 Pterostilbene
3 Radio Frequency
2 Serotonin, 5-hydroxytryptamine
2 Apigenin (mainly Parsley)
2 Artemisinin
2 Betulinic acid
2 Caffeic acid
2 Carnosic acid
2 Caffeine
2 chitosan
2 Lecithin
2 Chrysin
2 Ellagic acid
2 Emodin
2 Flickering Light Stimulation
2 Potassium
2 Luteolin
2 Propolis -bee glue
2 Shikonin
2 Ursolic acid
1 dietMediterranean
1 alpha Linolenic acid
1 Baicalin
1 Beta-Caryophyllene
1 borneol
1 α-Bisabolol / Chamomile oil
1 Cichoric acid / Chicoric acid
1 Rivastigmine
1 Date Fruit Extract
1 diet Fermented Foods
1 diet Methionine-Restricted Diet
1 Eurycomanone
1 Fisetin
1 Ginkgo biloba
1 Methylene blue
1 Naringin
1 Phenylbutyrate
1 Piperlongumine
1 S-adenosyl-L-methionine
1 Selenium
1 Metformin
1 Sesame seeds and Oil
1 Shankhpushpi
1 Chemotherapy
1 Thymol-Thymus vulgaris
1 Vitamin A, Retinoic Acid
1 probiotics
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:557  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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