BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.


Scientific Papers found: Click to Expand⟱
2605- Ba,  BA,    Potential therapeutic effects of baicalin and baicalein
- Review, Var, NA - Review, Stroke, NA - Review, IBD, NA - Review, Arthritis, NA - Review, AD, NA - Review, Park, NA
cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2/PTGS2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
2604- Ba,  BA,    Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats
- in-vivo, Nor, NA
*BioAv↝, *BioAv↝,
2597- Ba,    Baicalein – An Intriguing Therapeutic Phytochemical in Pancreatic Cancer
- Review, PC, NA
chemoP↑, ChemoSen↑, 12LOX?, Bcl-2↓, BAX↑, Mcl-1↓, ERK↓, Prx6↑, Dose↝, BioAv↓, eff↑,
2292- Ba,  BA,    Baicalin and baicalein in modulating tumor microenvironment for cancer treatment: A comprehensive review with future perspectives
- Review, Var, NA
AntiCan↑, *toxicity↓, BioAv↝, BioAv↓, *ROS↓, *TLR2↓, *NF-kB↓, *NRF2↑, *antiOx↑, *Inflam↓, HDAC1↓, HDAC8↓, Wnt↓, β-catenin/ZEB1↓, PD-L1↓, Sepsis↓, NF-kB↓, LOX1↓, COX2/PTGS2↓, VEGF↑, PI3K↓, Akt↓, mTOR↓, MMP2↓, MMP9↓, SIRT1↑, AMPK↑,
2290- Ba,    Research Progress of Scutellaria baicalensis in the Treatment of Gastrointestinal Cancer
- Review, GI, NA
p‑mTOR↓, p‑Akt↓, p‑IKKα↓, NF-kB↓, PI3K↓, Akt↓, ROCK1↓, GSK‐3β↓, CycB/CCNB1↓, cycD1/CCND1↓, cycA1/CCNA1↑, CDK4↓, P53↑, P21↑, TumCCA↑, MMP2↓, MMP9↓, EMT↓, Hif1a↓, Shh↓, PD-L1↓, STAT3↓, IL1β↓, IL2↓, IL6↓, PKM2↓, HDAC10↓, P-gp/ABCB1↓, Bcl-xL↓, eff↓, BioAv↓, BioAv↑,
5542- BBM,    Pharmacological profiling of a berbamine derivative for lymphoma treatment
- vitro+vivo, lymphoma, NA
CaMKII ↓, TumCG↓, cMyc↓, ROS↑, UPR↑, ER Stress↑, PERK↑, BioAv↑, toxicity↓,
5543- BBM,    Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo
- in-vivo, Lung, B16-F10 - vitro+vivo, Lung, A549 - in-vitro, BC, MDA-MB-231
BioAv↓, Half-Life↓, eff↑, TumMeta↓, TumCP↓, TumCG↓, Apoptosis↑, TumCCA↑, MMP2↓, MMP9↓, VEGF↓, Bcl-2↓, eff↑, EPR↑,
5550- BBM,  docx,  Chit,    Co-Delivery of Docetaxel and Berbamine by Chitosan/Sulfobutylether-β-Cyclodextrin Nanoparticles for Enhancing Bioavailability and Anticancer Activities
- in-vivo, Var, NA
eff↑, BioAv↑, Apoptosis↑, survivin↓,
2023- BBR,    Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor
- in-vitro, Colon, NA - in-vitro, Nor, YAMC
TumCD↑, *toxicity↓, selectivity↑, ROS↑, *ROS∅, MMP↓, *MMP∅, PARP↑, BioAv↝,
2022- BBR,  GoldNP,  Rad,    Berberine-loaded Janus gold mesoporous silica nanocarriers for chemo/radio/photothermal therapy of liver cancer and radiation-induced injury inhibition
- in-vitro, Liver, SMMC-7721 cell - in-vitro, Nor, HL7702
*toxicity↓, radioP↑, BioAv↑, AntiTum↑, selectivity↑, eff↑, chemoP↑,
2021- BBR,    Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways
- Review, Var, NA
*antiOx?, *Inflam↓, Apoptosis↑, TumCCA↑, BAX↑, Synergy↑, VEGF↓, PI3K↓, Akt↓, mTOR↓, Telomerase↓, β-catenin/ZEB1↓, Wnt↓, EGFR↓, AP-1↓, NF-kB↓, COX2/PTGS2↑, NRF2↓, RadioS↑, STAT3↓, ERK↓, AR↓, ROS↑, eff↑, selectivity↑, selectivity↑, BioAv↓, DNMT1↓, cMyc↓,
1405- BBR,  Chit,    Chitosan/alginate nanogel potentiate berberine uptake and enhance oxidative stress mediated apoptotic cell death in HepG2 cells
- in-vitro, Liver, HepG2
*BioAv↑, ROS↑, MMP↓, TumCP↓,
2678- BBR,    Berberine as a Potential Agent for the Treatment of Colorectal Cancer
- Review, CRC, NA
*Inflam↓, *antiOx↑, *cardioP↑, *neuroP↑, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDC2↓, AMPK↝, mTOR↝, Casp8↑, Casp9↑, Cyt‑c↑, TumCMig↓, TumCI↓, EMT↓, MMPs↓, E-cadherin↓, Telomerase↓, *toxicity↓, GRP78/BiP↓, EGFR↓, CDK4↓, COX2/PTGS2↓, PGE2↓, p‑JAK2↓, p‑STAT3↓, MMP2↓, MMP9↓, GutMicro↑, eff↝, *BioAv↓, BioAv↑,
2670- BBR,    Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases
- Review, Var, NA
*Inflam↓, *antiOx↑, *Ca+2↓, *BioAv↓, *BioAv↑, *BioAv↑, *angioG↑, *MAPK↓, *AMPK↓, *NF-kB↓, VEGF↓, PI3K↓, Akt↓, MMP2↓, Bcl-2↓, ERK↓,
2671- BBR,    Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I: A Mechanism for the Action of Berberine to Activate AMP-Activated Protein Kinase and Improve Insulin Action
- in-vivo, Diabetic, NA
*BioAv↓, *Half-Life↝, *OCR↓, *AMPK↑,
2672- BBR,    The anti-aging mechanism of Berberine associated with metabolic control
- Review, Var, NA
*BioAv↝, *BioAv↝, *BioAv↝, *Half-Life↓,
2673- BBR,    Therapeutic potential and recent delivery systems of berberine: A wonder molecule
- Review, Var, NA
*BioAv↓, *Half-Life↓, *neuroP↑, BBB↑, toxicity↓,
2674- BBR,    Berberine: A novel therapeutic strategy for cancer
- Review, Var, NA - Review, IBD, NA
Inflam↓, AntiCan↑, Apoptosis↑, TumAuto↑, TumCCA↑, TumMeta↓, TumCI↓, eff↑, eff↑, CD4+↓, TNF-α↓, IL1↓, BioAv↓, BioAv↓, other↓, AMPK↑, MAPK↓, NF-kB↓, IL6↓, MCP1/CCL2↓, PGE2↓, COX2/PTGS2↓, *ROS↓, *antiOx↑, *GPx↑, *Catalase↑, AntiTum↑, TumCP↓, angioG↓, Fas↑, FasL↑, ROS↑, ATM↑, P53↑, RB1↑, Casp9↑, Casp8↑, Casp3↓, BAX↑, Bcl-2↓, Bcl-xL↓, IAP1↓, XIAP↓, survivin↓, MMP2↓, MMP9↓, CycB/CCNB1↓, CDC25↓, CDC25↓, Cyt‑c↑, MMP↓, RenoP↑, mTOR↓, MDM2↓, LC3II↑, ERK↓, COX2/PTGS2↓, MMP3↓, TGF-β↓, EMT↑, ROCK1↓, FAK↓, RAS↓, Rho↓, NF-kB↓, uPA↓, MMP1↓, MMP13↓, ChemoSen↑,
6764- BBR,    Berberine as a therapeutic alkaloid against ESKAPE and multiple drug-resistant bacteria: a comprehensive review
- Review, Nor, NA
*AntiBio↑, *BioAv↓,
3678- BBR,    Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model
- Review, AD, NA
*APP↓, *PPARγ↑, *NF-kB↓, *Aβ↓, *cognitive↑, *antiOx↑, *Inflam↓, *Apoptosis↓, *BioAv↑, *BioAv↝, *BBB↑, *motorD↑, *NRF2↑, *HO-1↑, *ROS↓, *p‑Akt↑, *p‑ERK↑,
3680- BBR,    Network pharmacology reveals that Berberine may function against Alzheimer’s disease via the AKT signaling pathway
- in-vivo, AD, NA
*Akt↑, *neuroP↑, *p‑ERK↑, *Aβ↓, *Inflam↓, *ROS↓, *BioAv↑, *BBB↑, *Half-Life↝, *memory↑, *cognitive↑, *HSP90↑, *APP↓, *mTOR↓, *P70S6K↓, *CD31/PECAM-1↑, *VEGF↑, *N-cadherin↑, *Apoptosis↓,
5545- BBR,    Improving the oral bioavailability of berberine: A crystal engineering approach
- in-vivo, Nor, NA
BioAv↑,
5179- BBR,    Regulation of Cell Signaling Pathways by Berberine in Different Cancers: Searching for Missing Pieces of an Incomplete Jig-Saw Puzzle for an Effective Cancer Therapy
- Review, Var, NA
AMPK↑, Casp3↑, cl‑PARP↑, Mcl-1↓, cFLIP↓, β-catenin/ZEB1↓, Wnt↓, STAT3↓, mTOR↓, Hif1a↓, NF-kB↓, SIRT1↑, DNMT1↓, DNMT3A↓, miR-29b↓, IGFBP1↑, Synergy↑, chemoPv↑, BioAv↓,
5642- BCA,    Interactions between the flavonoid biochanin A and P-glycoprotein substrates in rats: in vitro and in vivo
- vitro+vivo, Nor, NA
P-gp/ABCB1↓, BioAv↓,
5640- BCA,    Improved effectiveness of biochanin A as a P-gp inhibitor in solid dispersion
- in-vitro, Nor, NA
*P-gp/ABCB1↓, BioAv↑, other↝, other↑,
5631- BCA,    Perspectives Regarding the Role of Biochanin A in Humans
- Review, Var, NA - Review, AD, NA
*BioAv↓, *Inflam↓, AntiCan↑, *neuroP↑, chemoPv↑, Dose↝, *SOD↑, *MDA↓, *BAX↓, *HSP70/HSPA5↑, *AntiDiabetic↑, *Insulin↑, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2/PTGS2↓, *MMP9↓, *ROS↓, *PGE2↓, *BACE/β-secretase↓, *BioAv↑, P-gp/ABCB1⇅,
5632- BCA,    Pharmacokinetics and bioavailability of the isoflavone biochanin A in rats
- in-vivo, Var, NA
chemoPv↑, *BioAv↓,
5633- BCA,    Mechanisms Behind the Pharmacological Application of Biochanin-A: A review
- Review, Var, NA - Review, AD, NA
*AntiDiabetic↑, *neuroP↑, *toxicity↓, *CYP19↓, p‑Akt↓, mTOR↓, TumCCA↑, P21↑, Casp3↑, Bcl-2↑, Apoptosis↑, E-cadherin↓, TumMeta↓, Synergy↑, GSK‐3β↓, β-catenin/ZEB1↓, RadioS↑, ROS↑, Casp1↑, MMP2↓, MMP9↓, EGFR↓, ChemoSen↑, PI3K↓, MMPs↓, Hif1a↓, VEGF↓, *ROS↓, *Obesity↓, *cardioP↑, *NRF2↑, *NF-kB↓, *Inflam↓, *lipid-P↓, *hepatoP↑, *AST↓, *ALP↓, *Bacteria↓, *neuroP↑, *SOD↑, *GPx↑, *AChE↓, *BACE/β-secretase↓, *memory↑, *BioAv↓,
5634- BCA,    Molecular Mechanisms of Biochanin A in AML Cells: Apoptosis Induction and Pathway-Specific Regulation in U937 and THP-1
- in-vitro, AML, U937 - in-vitro, AML, THP1
Apoptosis↑, Casp7↑, PARP1↑, Bcl-2↓, Myc↓, CHOP/DDIT3↑, P21↑, p62↑, TumCCA↑, TXNIP↑, ROS↑, *antiOx↑, *Inflam↓, *neuroP↑, AntiCan↑, TumCP↓, angioG↓, TumMeta↓, VEGF↓, MMPs↓, tumCV↓, DNAdam↑, CHOP/DDIT3↑, cMyc↓, BioAv↓, Half-Life↓, BioAv↑,
6515- BCP,  Xan,    Advancing Brain Health Naturally: β-Caryophyllene and Xanthohumol as Neuroprotective Agents
- Review, AD, NA
*neuroP↑, *BioAv↝, *CB2 / CNR2↑, *Inflam↓, *iNOS↓, *IL1β↓, *IL6↓, *TNF-α↓, *NF-kB↓, *COX1↓, *COX2/PTGS2↓, *PPARα↑, *PPARγ↑, *ROS↓, *tau↓, *NRF2↑, *HO-1↑, *AChE↓, *BChE↓, *BioAv↓,
6512- BCP,    Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells
- in-vitro, MM, NA
CB2 / CNR2↑, BAX↑, Bcl-2↓, Casp3↑, TumCP↓, Apoptosis↑, Akt↓, Wnt↓, β-catenin/ZEB1↓, TumCCA↑, Inflam↓, chemoPv↑, neuroP↑, *BioAv↝, CB2 / CNR2↑, tumCV↓,
6502- BCP,    Enhanced Oral Bioavailability of β-Caryophyllene in Healthy Subjects Using the VESIsorb® Formulation Technology, a Novel Self-Emulsifying Drug Delivery System (SEDDS)
- Study, Nor, NA
*BioAv↑, *BioAv↓, *BioAv↓, *eff↑,
6503- BCP,    The Potential Therapeutic Role of Beta-Caryophyllene as a Chemosensitizer and an Inhibitor of Angiogenesis in Cancer
- Review, Var, NA
ChemoSen↑, angioG↓, TumCI↓, TumMeta↓, ROS↑, *ROS↓, chemoP↑, CB2 / CNR2↑, Inflam↓, AntiTum↑, *BioAv↑, *BBB↑, Apoptosis↑, TumCP↑, TumCCA↑, RadioS↑, DNArepair↓, ROS↑, STAT3↓, *BioEnh↑, Pain↓, AntiBio↓, ROS↑, Dose↝, NF-kB↓, MAPK↓, TNF-α↓, IL1β↓, IL6↓, cl‑PARP↑, Casp↑, BAX↑, Bcl-2↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP2↓, p‑p38↓, p‑ERK↓, EPR↑, P-gp/ABCB1↓, MRP1/ABCC1↓, *NRF2↑, *antiOx↑,
5591- BetA,    Advances and challenges in betulinic acid therapeutics and delivery systems for breast cancer prevention and treatment
- Review, BC, NA
BioAv↓, BioAv↑, selectivity↑, eff↑, angioG↓, *antiOx↑, *Inflam↓, MMP↓, Bcl-2↓, BAX↑, Casp9↑, Casp3↑, GRP78/BiP?, ER Stress↑, PERK↑, CHOP/DDIT3↑, ChemoSen↑, SESN2↑, ROS↑, MOMP↓, MAPK↑, Cyt‑c↑, AIF↑, STAT3↓, FAK↓, TIMP2↑, TumCMig↓, TumCI↓, Sp1/3/4↓, TumCCA↑, DNAdam↑,
5589- BetA,    Advancements in Betulinic Acid-Loaded Nanoformulations for Enhanced Anti-Tumor Therapy
- Review, Var, NA
BioAv↓, toxicity↝, BioAv↑, Half-Life↑,
5588- BetA,    Therapeutic applications of betulinic acid nanoformulations
- Review, Var, NA
BioAv↓, Half-Life↓, BioAv↑, Half-Life↑,
2731- BetA,    Betulinic Acid for Glioblastoma Treatment: Reality, Challenges and Perspectives
- Review, GBM, NA - Review, Park, NA - Review, AD, NA
BBB↑, *GSH↑, *Catalase↑, *motorD↑, *neuroP↑, *cognitive↑, *ROS↓, *antiOx↑, *Inflam↓, MMP↓, STAT3↓, NF-kB↓, Sp1/3/4↓, TOP1↓, EMT↓, Hif1a↓, VEGF↓, ChemoSen↑, RadioS↑, BioAv↓,
2735- BetA,    Betulinic acid as apoptosis activator: Molecular mechanisms, mathematical modeling and chemical modifications
- Review, Var, NA
mt-Apoptosis↑, Casp↑, p38↑, MAPK↓, JNK↓, VEGF↓, AIF↑, Cyt‑c↑, ROS↑, Ca+2↑, ATP↓, NF-kB↓, ATF3↓, TOP1↓, VEGF↓, survivin↓, Sp1/3/4↓, MMP↓, ChemoSen↑, selectivity↑, BioAv↓, BioAv↑, BioAv↑, BioAv↑, BioAv↑,
2762- BetA,    Targeting Effect of Betulinic Acid Liposome Modified by Hyaluronic Acid on Hepatoma Cells In Vitro
- in-vitro, Liver, HepG2
ROCK1↓, RAS↓, *BioAv↓, BioAv↑,
2748- BetA,    Betulinic Acid: Recent Advances in Chemical Modifications, Effective Delivery, and Molecular Mechanisms of a Promising Anticancer Therapy
- Review, Var, NA
Bcl-2↓, MMP↓, Cyt‑c↑, Casp↑, Diablo↑, AIF↑, angioG↓, BioAv↓, NF-kB↓,
3989- betaCar,    Dietary factors that affect the bioavailability of carotenoids
- Review, Nor, NA
*BioAv↑, *BioAv↑,
5597- Bical,    Bicalutamide: clinical pharmacokinetics and metabolism
- Review, Pca, NA
Dose↝, BioAv↑, Half-Life↑, CYP3A4↓, PSA↓,
5473- BM,    Bacopa monnieri: Preclinical and Clinical Evidence of Neuroactive Effects, Safety of Use and the Search for Improved Bioavailability
- in-vivo, AD, NA - in-vivo, Park, NA
*neuroP↑, *toxicity∅, *AChE↓, *ROS↓, *antiOx↑, *lipid-P↓, *cognitive↑, *memory↑, *Dose↝, *BioAv↓, *TumCCA↑, *BBB↝,
5649- BNL,    Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood–brain barrier permeability
- Review, Nor, NA
*BBB↑, *other↑, *P-gp/ABCB1↓, *toxicity⇅, *BioAv⇅, *Dose↑, *ABC↓, *MRP1/ABCC1↓, *5HT↑, *GABA↑, *Synergy↑,
5654- BNL,    Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio
- in-vivo, Nor, NA
*BioAv↑, *Half-Life↝, other↝,
5655- BNL,    Comparative pharmacokinetic studies of borneol in mouse plasma and brain by different administrations
- in-vivo, Nor, NA
*BioAv↝, BioAv↓, BioAv↑,
5660- BNL,    Recent Progress on the Synergistic Antitumor Effect of a Borneol-Modified Nanocarrier Drug Delivery System
- Review, Var, NA
TumMeta↓, BBB↑, EPR↑, toxicity↓, BioAv↑, ChemoSen↑, eff↑, other↑, P-gp/ABCB1↓, MDR1↓, ROS↑, TumCCA↑, other↝, BioAv↓, DNAdam↑, BioEnh↑,
5663- BNL,    Osthole/borneol thermosensitive gel via intranasal administration enhances intracerebral bioavailability to improve cognitive impairment in APP/PS1 transgenic mice
- in-vivo, AD, NA
*ZO-1↓, *cl‑Casp3↓, *Bax:Bcl2↓, *MDA↓, *Apoptosis↓, *Aβ↓, *BACE/β-secretase↓, *cognitive↑, *BioAv↑, memory↑, P-gp/ABCB1↓, BioEnh↑,
5664- BNL,    Enhancing effect of natural borneol on the absorption of geniposide in rat via intranasal administration
- in-vivo, Nor, NA
*BioAv↑, eff↑,
5666- BNL,    Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider
- in-vivo, AD, NA
*BioAv↑, *eff↑, *Dose↝, *P-gp/ABCB1↓, *BBB↑, *NF-kB↓, *IL1β↓, *MMP9↓,

Showing Research Papers: 101 to 150 of 856
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 856

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 5,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 17,   ARE↓, 1,   Catalase↓, 7,   Catalase↑, 5,   Fenton↑, 4,   frataxin↑, 1,   GPx↓, 3,   GPx↑, 5,   GPx4↓, 11,   GPx4↑, 1,   GSH↓, 34,   GSH↑, 7,   GSH/GSSG↓, 1,   GSR↓, 2,   GSR↑, 1,   ox-GSSG↑, 1,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 4,   e-H2O2↓, 1,   i-H2O2∅, 1,   HO-1↓, 6,   HO-1↑, 10,   HO-2↓, 1,   Iron↑, 5,   Iron↝, 1,   i-Iron↑, 1,   c-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 8,   lipid-P↑, 15,   MDA↓, 3,   MDA↑, 5,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NOX4↑, 1,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 16,   NRF2↑, 23,   Prx↓, 1,   Prx4↑, 1,   Prx6↑, 1,   ox-PrxI↑, 1,   PrxII↓, 1,   PYCR1↓, 1,   ROS?, 1,   ROS↓, 28,   ROS↑, 235,   ROS⇅, 9,   ROS↝, 3,   i-ROS↓, 1,   i-ROS↑, 2,   mt-ROS↑, 1,   SOD↓, 9,   SOD↑, 8,   SOD1↓, 2,   SOD2↓, 4,   SOD2↑, 1,   Thiols↓, 2,   Trx↓, 2,   Trx1↑, 1,   TrxR↓, 8,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 5,   Tf↓, 1,   Tf↑, 1,   TfR1/CD71↑, 2,   Zn2+↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 2,   BCR-ABL↓, 1,   CDC2↓, 4,   CDC25↓, 5,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   compV↓, 1,   EGF↓, 2,   ETC↓, 3,   ETC↑, 1,   MFN2↑, 1,   mitResp↓, 2,   Mortalin↓, 1,   mtDam↓, 1,   mtDam↑, 15,   OCR↓, 2,   OCR↑, 3,   OXPHOS↓, 5,   OXPHOS↑, 3,   mt-OXPHOS↓, 2,   PDH↑, 2,   PGC-1α↑, 1,   PINK1↑, 1,   SDH↑, 1,   SIRT3↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 1,   5LO↓, 5,   ACLY↓, 2,   ACSL4↑, 1,   ALAT↓, 6,   ALAT↑, 1,   ALDOA↓, 1,   AMPK↑, 19,   AMPK↝, 1,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 18,   ATP↑, 1,   mt-ATP↓, 1,   CAIX/CA9↓, 1,   CAIX/CA9↑, 1,   CRM↝, 1,   ECAR↓, 3,   ECAR↝, 1,   ENO1↓, 2,   FASN↓, 5,   FDG↓, 1,   GAPDH↓, 2,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↓, 1,   GlucoseCon↓, 12,   GlutaM↓, 1,   GlutMet↓, 1,   Glycolysis↓, 36,   Glycolysis↝, 1,   GSK‐3β↓, 14,   GSK‐3β↑, 5,   p‑GSK‐3β↓, 1,   H2S↑, 1,   HK1↓, 1,   HK2↓, 18,   HMG-CoA↓, 1,   IDH1↓, 1,   lactateProd↓, 14,   lactateProd↑, 1,   LDHA↓, 3,   LDL↓, 4,   lipoGen↓, 1,   MCT4↓, 2,   NADH:NAD↓, 1,   NADPH↓, 4,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 8,   PDK3↑, 1,   PFK1↓, 1,   PKM2↓, 11,   SCD1↓, 1,   SIRT1↓, 8,   SIRT1↑, 8,   SIRT2↓, 1,   SIRT2↑, 1,   SREBP1/SREBF1↓, 1,   TCA↓, 2,   TCA↑, 1,   TCA↝, 1,   UGDH↓, 2,   Warburg↓, 11,  

Cell Death(tgid=5) ⓘ

AIF↑, 13,   APAF1↑, 4,   Apoptosis?, 1,   Apoptosis↓, 2,   Apoptosis↑, 190,   mt-Apoptosis↑, 2,   ASC↓, 1,   BAD↓, 2,   BAD↑, 4,   Bak↓, 1,   Bak↑, 6,   BAX↓, 3,   BAX↑, 84,   Bax:Bcl2↓, 1,   Bax:Bcl2↑, 20,   Bcl-2↓, 85,   Bcl-2↑, 4,   Bcl-xL↓, 20,   BID↓, 1,   BID↑, 3,   p‑BID↓, 1,   BIM↓, 1,   BIM↑, 4,   BNIP3↑, 1,   BNIP3↝, 1,   BOK↑, 1,   Casp↑, 39,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 3,   Casp12?, 1,   Casp12↑, 1,   cl‑Casp12↑, 1,   Casp3↓, 2,   Casp3↑, 101,   Casp3↝, 1,   cl‑Casp3↑, 13,   cl‑Casp3⇅, 1,   proCasp3↑, 1,   Casp6↑, 1,   Casp7↑, 14,   cl‑Casp7↑, 2,   Casp8↑, 23,   cl‑Casp8↑, 2,   proCasp8↑, 1,   pro‑Casp8↑, 1,   Casp9↓, 1,   Casp9↑, 61,   cl‑Casp9↑, 6,   proCasp9↓, 1,   cFLIP↓, 3,   Cyt‑c↓, 3,   Cyt‑c↑, 56,   Cyt‑c↝, 1,   Diablo↑, 3,   DR5↑, 19,   Endon↑, 1,   FADD↑, 5,   Fas↑, 11,   FasL↓, 1,   FasL↑, 6,   Ferroptosis↑, 20,   GranB/GZMB↓, 1,   GranB/GZMB↝, 1,   GSDME↑, 1,   IAP1↓, 4,   IAP2/BIRC3↓, 2,   IAP2/BIRC3↑, 1,   ICD↑, 1,   iNOS↓, 15,   Mcl-1↓, 18,   Mcl-1↑, 1,   p‑Mcl-1↓, 1,   MDM2↓, 8,   MDM2↑, 2,   p‑MDM2↓, 1,   MOMP↓, 1,   MOMP↑, 4,   NAIP↓, 1,   Necroptosis↑, 2,   necrosis↑, 4,   NOXA↑, 4,   p38↓, 2,   p38↑, 14,   p‑p38↓, 1,   p‑p38↑, 2,   Paraptosis↑, 1,   Perforin↝, 1,   pS2/TFF1↓, 1,   PUMA↓, 1,   PUMA↑, 5,   Pyro↑, 3,   RIP1↑, 1,   RIP3↑, 1,   survivin↓, 37,   TRAIL↑, 2,   TRAIL⇅, 1,   TRAILR↑, 1,   TumCD↓, 2,   TumCD↑, 17,   XIAP↓, 20,   XIAP↑, 1,   YAP/TEAD↓, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 2,   Akt↓, 126,   Akt↑, 6,   p‑Akt↓, 31,   AKT1↓, 3,   Akt2↓, 1,   AMPKα↑, 1,   BRAF↓, 1,   CaMKII ↓, 1,   CIP2A↓, 1,   CK2↓, 2,   cMET↓, 3,   cSrc↓, 2,   DDIT4↑, 1,   DYRK1B↓, 1,   EF-1α↓, 1,   EGFR↓, 30,   EGFR↑, 2,   p‑EGFR↓, 1,   ERK↓, 42,   ERK↑, 5,   p‑ERK↓, 12,   FGFR1↓, 3,   FGFR2↓, 1,   FOXD3↑, 1,   HER2/EBBR2↓, 7,   HGF/c-Met↓, 3,   Hippo↑, 1,   IGF-1R↓, 3,   IGF-2R↑, 1,   IKKα↓, 3,   p‑IKKα↓, 1,   IκB↓, 1,   IκB↑, 1,   JAK↓, 5,   JAK1↓, 3,   JAK1↑, 1,   JAK2↓, 9,   p‑JAK2↓, 1,   JNK↓, 6,   JNK↑, 16,   p‑JNK↑, 2,   LIMK1↓, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 32,   MAPK↑, 13,   MAPK↝, 2,   p‑MAPK↓, 1,   MARK4↓, 2,   MEK↓, 3,   mTOR↓, 70,   mTOR⇅, 1,   mTOR↝, 2,   p‑mTOR↓, 6,   p‑p70S6↓, 1,   P70S6K↓, 2,   p‑P70S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 98,   PI3K↑, 3,   PI3K↝, 1,   p‑PI3K↓, 4,   p‑PI3K↑, 1,   PKA↓, 2,   PKCδ↓, 7,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 33,   Raf↓, 3,   c-Raf↓, 1,   RAS↓, 11,   RET↓, 1,   SHP1↑, 1,   Sp1/3/4↓, 6,   Sp1/3/4↑, 1,   Src↓, 3,   p‑Src↓, 1,   STAT↓, 3,   STAT3↓, 65,   STAT3↑, 3,   p‑STAT3↓, 10,   p‑STAT3↑, 2,   STAT6↓, 3,   p‑STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↓, 1,   ATF4↑, 6,   ATF4↝, 1,   CBP↓, 2,   cJun↓, 3,   cJun↑, 1,   p‑cJun↑, 1,   cMyc↓, 34,   cMyc↑, 1,   p‑cMyc↑, 1,   DNMT1↓, 7,   DNMT3A↓, 2,   DNMTs↓, 7,   EZH2↓, 5,   FOXM1↓, 4,   FOXO1↓, 2,   FOXO1↑, 2,   FOXO3↓, 1,   FOXO3↑, 4,   FOXO3↝, 1,   FOXO4↑, 2,   H3↓, 2,   H3↑, 2,   ac‑H3↑, 1,   H4↓, 1,   H4↑, 2,   HATs↓, 4,   HATs↑, 4,   HDAC↓, 27,   HDAC1↓, 8,   HDAC10↓, 1,   HDAC2↓, 6,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC8↓, 2,   HES1↓, 1,   miR-106b↓, 2,   miR-107↑, 1,   miR-124-3p↓, 1,   miR-139-5p↑, 1,   miR-155↓, 2,   miR-19b↓, 2,   miR-200b↑, 1,   miR-203↑, 1,   miR-21↓, 7,   miR-218↑, 1,   miR-224↓, 1,   miR-25-5p↓, 1,   miR-27a-3p↓, 1,   miR-29b↓, 1,   miR-30a-5p↑, 1,   miR-339-5p↝, 1,   miR-340↓, 1,   miR-34a↓, 2,   miR-34a↑, 6,   miR-375↑, 1,   miR-384↑, 1,   miR-422a↑, 1,   miR-590-3p↑, 1,   MTA2↓, 1,   Myc↓, 5,   MYCN↓, 1,   OCT4↓, 9,   other↓, 2,   other↑, 8,   other↝, 40,   other∅, 1,   PhotoS↑, 3,   SD↑, 1,   sonoS↑, 1,   SOX2↓, 6,   SOX4↓, 2,   SOX4↑, 1,   SOX9?, 1,   tumCV?, 1,   tumCV↓, 24,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 15,   cl‑CHOP/DDIT3↑, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↓, 1,   eIF2α↑, 4,   p‑eIF2α↑, 2,   ER Stress↓, 1,   ER Stress↑, 34,   GRP78/BiP?, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 6,   GRP78/BiP↝, 1,   HSP27↝, 1,   HSP70/HSPA5↓, 2,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 12,   PERK↑, 8,   Proteasome↓, 1,   UPR↑, 6,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   ATG7↑, 2,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 8,   CTSK↓, 1,   LAMP1?, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B-II↑, 2,   LC3II↓, 2,   LC3II↑, 14,   p62↓, 5,   p62↑, 3,   PARK2↑, 1,   SESN2↑, 2,   TFEB↑, 1,   TumAuto↓, 2,   TumAuto↑, 38,   TumAuto⇅, 1,   TumAuto↝, 2,  

DNA Damage & Repair(tgid=10) ⓘ

APE1/APEX1↓, 1,   ATM?, 1,   ATM↑, 2,   BRCA1↓, 2,   p‑BRCA1↑, 1,   DFF45↓, 1,   DNAdam↓, 3,   DNAdam↑, 51,   DNAdamC↑, 1,   DNArepair↓, 3,   DNArepair↑, 1,   ERCC3↑, 1,   m-FAM72A↓, 1,   G9a↓, 1,   hTERT/TERT↓, 13,   MGMT↓, 2,   NKX3.1↓, 1,   p16↑, 2,   P53?, 1,   P53↓, 4,   P53↑, 72,   p‑P53↑, 1,   p53 Wildtype↓, 1,   p53 Wildtype↑, 1,   p53 Wildtype∅, 1,   p73↑, 1,   PARP↓, 1,   PARP↑, 19,   cl‑PARP↓, 2,   cl‑PARP↑, 49,   PARP1↑, 1,   PCNA↓, 17,   SIRT6↑, 1,   Telomerase↓, 16,   TOP1?, 1,   TOP1↓, 11,   TOP2↓, 6,   TOP2↑, 2,   TP53↑, 4,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↓, 1,   γH2AX↑, 3,   γH2AX↝, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 8,   CDK1↑, 5,   CDK2↓, 30,   CDK2↑, 1,   CDK4↓, 39,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 11,   CDK6↑, 1,   CDK7↓, 1,   CDK8↓, 1,   CDKN1C/p57↓, 1,   CDKN1C/p57↑, 1,   CHK1↓, 2,   p‑CHK1↑, 1,   Chk2↓, 2,   Cyc↓, 1,   cycA1/CCNA1↓, 3,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 21,   CycB/CCNB1↑, 4,   cycD1/CCND1↓, 54,   cycD1/CCND1↑, 2,   p‑cycD1/CCND1↓, 1,   CycD3↓, 1,   cycE/CCNE↓, 13,   E2Fs↓, 5,   E2Fs↑, 1,   Ki-67↓, 27,   mitA↑, 3,   p19↑, 1,   P21?, 1,   P21↓, 1,   P21↑, 42,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 16,   pRB↓, 1,   RB1↑, 1,   p‑RB1↓, 5,   Securin↓, 1,   TubPol↓, 1,   TumCCA↓, 6,   TumCCA↑, 169,   UBE2C↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 7,   ALDH1A1↓, 2,   ALDH1A3↓, 1,   Axin2↑, 1,   BMP7/OP1↓, 1,   BMPs↑, 2,   CD133↓, 3,   CD133↑, 1,   CD34↓, 1,   cFos↓, 4,   cFos↑, 1,   cMYB↓, 2,   CSCs?, 1,   CSCs↓, 43,   Diff↑, 2,   EIF4E↓, 1,   FGF↓, 3,   Gli↓, 2,   Gli1↓, 9,   HH↓, 10,   HH∅, 1,   HMGCR↓, 1,   IGF-1↓, 6,   IGFBP1↑, 1,   IGFBP3↑, 1,   JAG1↓, 1,   Ki-67↓, 27,   Let-7↑, 3,   LRP6↓, 1,   mTORC1↓, 5,   Nanog↓, 10,   Nestin↓, 2,   NICD↓, 1,   NOTCH↓, 16,   NOTCH1↓, 12,   NOTCH1↑, 4,   NOTCH3↓, 2,   p300↓, 2,   PTCH1↓, 1,   PTCH2↓, 1,   Shh↓, 8,   Smo↓, 3,   STAT1↓, 1,   TAZ↓, 1,   TumCG↓, 70,   TumCG↑, 3,   TumCP?, 1,   TumCP↓, 130,   TumCP↑, 5,   TumCP⇅, 1,   tyrosinase↓, 2,   Wnt↓, 41,   Wnt↝, 1,   Wnt/(β-catenin)↓, 2,   Zn2+↑, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   annexin II↓, 1,   AP-1↓, 10,   ASAP2↓, 1,   AXL↓, 1,   BACH1↓, 1,   CA↓, 1,   Ca+2↓, 3,   Ca+2↑, 18,   Ca+2↝, 2,   Cav1↓, 1,   Cdc42↓, 1,   Cdc42↑, 1,   CTNNB1↓, 1,   E-cadherin↓, 9,   E-cadherin↑, 30,   EMT↓, 64,   EMT↑, 1,   EpCAM↓, 2,   FAK↓, 11,   FAK↑, 1,   p‑FAK↓, 4,   fascin↓, 1,   Fibronectin↓, 1,   GLI2↓, 1,   hnRNPA1↓, 1,   ITGB1↓, 3,   ITGB3↓, 1,   ITGB6↓, 1,   KRAS↓, 2,   LAMs↓, 2,   MALAT1↓, 3,   MET↓, 1,   p‑MET↓, 1,   MMP-10↓, 1,   MMP1↓, 5,   MMP13↓, 4,   MMP15↓, 1,   MMP16↓, 1,   MMP2↓, 77,   MMP2↑, 1,   MMP3↓, 7,   MMP7↓, 9,   MMP9↓, 90,   MMP9↑, 4,   MMPs↓, 35,   MUC4↓, 2,   N-cadherin↓, 20,   PDGF↓, 5,   Rac1↓, 2,   RECK↑, 1,   Rho↓, 4,   Rho↑, 1,   ROCK1↓, 5,   ROCK1↑, 1,   Slug↓, 7,   Smad1↓, 1,   SMAD3↓, 1,   Snail↓, 12,   TET1?, 1,   TET1↑, 5,   TGF-β↓, 10,   TIMP1↓, 1,   TIMP1↑, 13,   TIMP2↑, 11,   TIMP3↑, 1,   TRIB3↑, 3,   TSC1↑, 1,   TumCA↓, 4,   TumCI↓, 69,   TumCMig↓, 55,   TumCMig↑, 1,   TumMeta?, 1,   TumMeta↓, 86,   TumMeta↑, 7,   TumPF↓, 1,   Twist↓, 14,   TXNIP↑, 1,   Tyro3↓, 1,   uPA↓, 14,   uPAR↓, 1,   Vim↓, 25,   Vim↑, 1,   Zeb1↓, 9,   ZEB2↓, 2,   α-SMA↓, 2,   α-SMA↑, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 44,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 117,   angioG↑, 2,   CD31/PECAM-1↓, 6,   EGR1↑, 1,   EGR4↓, 1,   Endoglin↑, 2,   HIF-1↓, 7,   Hif1a↓, 62,   Hif1a↝, 1,   LOX1↓, 2,   NO↓, 4,   NO↑, 1,   PGI2↓, 1,   VCAM-1↓, 3,   VEGF↓, 100,   VEGF↑, 1,   VEGFR1↓, 3,   VEGFR2/KDR/Flk1↓, 8,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 16,   CLDN1↓, 4,   CLDN1↑, 1,   CX43/GJA1↓, 1,   EPR↑, 16,   GLUT1↓, 8,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↓, 2,   IBI↑, 1,   MMP↓, 80,   MMP↑, 2,   MPT↑, 6,   NHE1↓, 2,   OATPs↓, 2,   OCLN↑, 1,   TJ↓, 1,   TJ↑, 1,   TRPV1↑, 3,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 3,   CD4+↓, 1,   CD4+↑, 1,   CD44↓, 9,   CD47↓, 1,   CD8+↑, 2,   p‑cDC2↓, 1,   COX1↓, 2,   COX1↑, 1,   COX2/PTGS2↓, 71,   COX2/PTGS2↑, 5,   CXCL12↓, 1,   CXCR4↓, 9,   Dectin1↝, 1,   DR4↑, 5,   FOXP3↓, 2,   FOXP3↑, 1,   Gal-3↓, 1,   GM-CSF↓, 1,   HCAR1↓, 1,   HLA↑, 1,   HLA-I/II↑, 1,   HMGB1↓, 2,   ICAM-1↓, 5,   IFN-γ↓, 1,   IFN-γ↑, 3,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 6,   IL1↑, 1,   IL10↓, 4,   IL10↑, 3,   IL12↓, 1,   IL12↑, 1,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 20,   IL1β↑, 1,   IL2↓, 4,   IL2↑, 7,   IL4↑, 1,   IL6↓, 38,   IL8↓, 10,   Imm↑, 18,   Imm↝, 2,   INF-γ↓, 1,   Inflam↓, 42,   IRAK1↓, 1,   LRIG1↑, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 3,   MCT1↓, 2,   MDSCs↓, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   mPGES-1↓, 1,   NAF1↓, 1,   NF-kB?, 1,   NF-kB↓, 141,   NF-kB↑, 4,   p‑NF-kB↓, 1,   p‑NF-kB↑, 2,   NK cell↑, 7,   NLRP3↓, 3,   NLRP3↑, 2,   NOD1↓, 1,   p65↓, 4,   p‑p65↓, 2,   PD-1↓, 3,   PD-1↝, 2,   PD-L1↓, 11,   PGE1↓, 1,   PGE2↓, 22,   PSA↓, 12,   SOCS-3↓, 1,   T-Cell↑, 1,   TCF↓, 1,   Th1 response↑, 1,   TLR4↓, 5,   TLR4↝, 1,   TNF-α↓, 37,   TNF-α↑, 5,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   Treg lymp↓, 3,  

Cellular Microenvironment(tgid=17) ⓘ

pH↓, 1,   pH↑, 1,   e-pH↑, 2,   i-pH↓, 1,   TAMS↓, 1,   TAMS↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   PTN↓, 1,   SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

2/16-OHE1↑, 1,   2/16-OHE1↝, 1,   AhR↓, 1,   AhR↓, 1,   AR↓, 17,   AR↝, 2,   AR-FL↓, 1,   AR-V7↑, 1,   COMT↓, 2,   CYP17A1↓, 1,   CYP19↓, 2,   ENL↑, 1,   ER(estro)↓, 2,   ERα/ESR1↓, 1,   Estro↝, 1,   FGF21↓, 1,   FKBP5↓, 1,   PPARα↓, 2,   PPARγ↓, 1,   PPARγ↑, 3,   RANKL↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 175,   BioAv↑, 235,   BioAv⇅, 2,   BioAv↝, 74,   BioEnh?, 1,   BioEnh↑, 7,   CBR1↓, 1,   chemoR↓, 2,   ChemoSen?, 1,   ChemoSen↓, 2,   ChemoSen↑, 197,   ChemoSen⇅, 2,   CompStab?, 1,   CompStab↓, 7,   CompStab↑, 7,   CompStab↝, 3,   CYP1A1↓, 6,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP1A2↑, 2,   CYP2A3/CYP2A6↓, 1,   CYP2C9↓, 1,   CYP2E1↑, 1,   CYP3A2↓, 1,   CYP3A4↓, 4,   DDS↑, 10,   Dose?, 4,   Dose↓, 4,   Dose↑, 16,   Dose↝, 90,   Dose∅, 11,   DrugR↓, 1,   eff?, 1,   eff↓, 28,   eff↑, 129,   eff⇅, 1,   eff↝, 13,   eff∅, 3,   GSTA1↑, 2,   GSTM1↑, 1,   GSTZ1↓, 1,   GSTZ1↝, 1,   Half-Life↓, 33,   Half-Life↑, 12,   Half-Life↝, 36,   Half-Life∅, 5,   MDR1↓, 10,   MRP↓, 1,   MRP1/ABCC1↓, 5,   MRP1/ABCC1↑, 1,   MRP1/ABCC1↝, 1,   P-gp/ABCB1↓, 22,   P-gp/ABCB1↑, 3,   P-gp/ABCB1⇅, 1,   P450↓, 4,   RadioS?, 1,   RadioS↑, 69,   RadioS↝, 1,   selectivity?, 1,   selectivity↑, 86,   selectivity↝, 1,   selectivity∅, 1,   Synergy↑, 111,   Synergy↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 6,   ALAT↑, 1,   ALP↓, 2,   AR↓, 17,   AR↝, 2,   ascitic↓, 1,   AST↓, 4,   AST↑, 1,   BMD↑, 1,   BP↓, 2,   BRAF↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CEA↓, 2,   CEC↝, 1,   CRP↓, 2,   E6↓, 2,   E7↓, 2,   EGFR↓, 30,   EGFR↑, 2,   p‑EGFR↓, 1,   ERα/ESR1↓, 1,   EZH2↓, 5,   Ferritin↓, 1,   FOXM1↓, 4,   HER2/EBBR2↓, 7,   hTERT/TERT↓, 13,   IL6↓, 38,   KRAS↓, 2,   LDH↓, 5,   LDH↑, 1,   LDH↝, 1,   Myc↓, 5,   NOS2↓, 1,   NOS2↑, 1,   NSE↓, 1,   PD-L1↓, 11,   PSA↓, 12,   TF-Ag↓, 1,   TG/TAG↓, 1,   TP53↑, 4,   TRIB3↑, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiArt↑, 1,   AntiCan↓, 3,   AntiCan↑, 79,   AntiCan∅, 1,   antiD↑, 1,   AntiDiabetic↑, 1,   antiNeop↑, 3,   antiPs↑, 1,   AntiTum↑, 29,   cachexia↓, 3,   cardioP↑, 22,   CardioT↓, 1,   CardioT↑, 1,   chemoP↑, 41,   chemoPv↑, 22,   ChemoSideEff↓, 7,   cognitive?, 1,   cognitive↑, 4,   fatigue↓, 2,   hepatoP↓, 3,   hepatoP↑, 14,   memory↑, 4,   Mucositis↓, 1,   neuroP↑, 13,   NP/CIPN↓, 3,   NP/CIPN↑, 1,   Obesity↓, 1,   ORR↑, 1,   OS↑, 18,   OS↝, 1,   OS∅, 1,   Pain↓, 5,   PFS↓, 1,   PFS↑, 1,   PFS∅, 1,   QoL↑, 5,   QoL↝, 1,   radioP↑, 10,   Remission↑, 2,   RenoP↑, 5,   Risk↓, 29,   Risk↑, 1,   Sleep↑, 1,   toxicity↓, 38,   toxicity↑, 8,   toxicity⇅, 2,   toxicity↝, 21,   toxicity∅, 4,   TumVol↓, 20,   TumW↓, 7,   Weight↑, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiViral↑, 1,   Bacteria↓, 1,   Dectin1↝, 1,   GutMicro↑, 11,   GutMicro↝, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 2,   Ingr↝, 2,  
Total Targets: 1036

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 1,   antiOx?, 1,   antiOx↓, 16,   antiOx↑, 188,   ARE↑, 4,   ARE↝, 1,   Catalase↓, 1,   Catalase↑, 67,   Fenton↓, 2,   GPx↓, 1,   GPx↑, 53,   GPx1↑, 2,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 65,   GSR↑, 9,   GSTs↓, 3,   GSTs↑, 17,   H2O2↓, 7,   H2O2↑, 1,   H2O2∅, 2,   HDL↑, 5,   HDL∅, 1,   HNE↓, 1,   HO-1↓, 2,   HO-1↑, 46,   HO-2↓, 1,   Iron↓, 1,   Keap1↓, 2,   Keap1↑, 2,   Keap1↝, 1,   lipid-P↓, 57,   mt-lipid-P↓, 1,   MDA↓, 51,   MPO↓, 10,   NADH↓, 1,   NOX↓, 1,   NQO1↑, 10,   NQO1↝, 1,   NQO1∅, 1,   Nrf1↑, 2,   NRF2?, 1,   NRF2↓, 3,   NRF2↑, 74,   NRF2⇅, 1,   NRF2↝, 1,   Prx↑, 1,   RNS↓, 5,   ROS?, 1,   ROS↓, 222,   ROS↑, 4,   ROS⇅, 4,   ROS∅, 2,   mt-ROS?, 1,   selenoP↑, 4,   SOD↓, 5,   SOD↑, 96,   mt-SOD↑, 1,   SOD1↑, 5,   SOD2↑, 3,   TAC↑, 7,   TBARS↓, 2,   Thiols↑, 1,   Trx↑, 2,   Trx1↑, 1,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 5,   VitE↑, 4,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   IronCh↑, 13,   IronCh↝, 1,   Mets↝, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 2,   compII↑, 2,   compIII↑, 2,   compIV↑, 1,   DRP1/DNM1L↓, 1,   ETC↑, 1,   Insulin↓, 2,   Insulin↑, 4,   Insulin↝, 1,   MFN2↑, 1,   mtDam↓, 4,   OCR↓, 1,   OCR↑, 2,   OXPHOS↑, 1,   PGC-1α↑, 4,   PGC-1α↝, 1,   PINK1↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   15-LOX/ALOX15↓, 1,   5LO↓, 5,   ACC↓, 1,   Acetyl-CoA↑, 1,   adiP↑, 1,   ALAT↓, 18,   ALAT∅, 2,   AMPK↓, 2,   AMPK↑, 16,   AMPK↝, 1,   ATP↓, 1,   ATP↑, 11,   Buty↑, 1,   cAMP↑, 2,   CRM↑, 1,   cytoP450↓, 1,   DHODH↓, 1,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 1,   FFA/NEFA↓, 1,   G6PD↑, 1,   glucose↓, 8,   glucose↝, 4,   GlucoseCon↑, 5,   GlutMet↑, 1,   glyC↓, 1,   Glycolysis↓, 1,   GSK‐3β↓, 13,   GSK‐3β↑, 3,   p‑GSK‐3β↑, 1,   H2S↑, 1,   HMG-CoA↓, 2,   LDHA↑, 1,   LDL↓, 15,   lipidLev↓, 6,   lipoGen↓, 1,   NAD↓, 1,   NAD↑, 2,   NADH:NAD↑, 1,   NADPH↓, 3,   NADPH↑, 4,   PDK1 / PDPK1↓, 1,   PFK↓, 1,   PLA2↓, 2,   SCFAs↑, 1,   SIRT1↑, 21,   SIRT1↝, 1,   SIRT2↑, 1,   SREBF2↓, 1,   SREBF2⇅, 1,   SREBP1/SREBF1↓, 1,   SREBP1/SREBF1↑, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Apoptosis↓, 15,   ASC↓, 1,   BAX↓, 11,   Bax:Bcl2↓, 2,   Bcl-2↓, 3,   Bcl-2↑, 9,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 24,   cl‑Casp3↓, 1,   Casp6↓, 1,   Casp8↓, 1,   Casp9↓, 11,   Casp9↑, 1,   Cyt‑c↓, 5,   Cyt‑c∅, 1,   Fas↓, 1,   Ferroptosis↓, 2,   GranB/GZMB↓, 1,   iNOS↓, 27,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 3,   Pyro↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 5,   Akt↑, 19,   Akt↝, 1,   p‑Akt↓, 1,   p‑Akt↑, 3,   Akt2↓, 1,   AMPKα↑, 1,   CREB↑, 4,   p‑CREB↑, 1,   ERK↓, 6,   ERK↑, 5,   p‑ERK↑, 3,   HGF/c-Met↑, 1,   IGF-1R↓, 1,   IKKα↓, 2,   JAK↓, 2,   JAK2↓, 1,   JAK2↑, 1,   JNK↓, 7,   p‑JNK↓, 3,   MAPK↓, 17,   MAPK↑, 2,   MAPK↝, 2,   mTOR↓, 3,   mTOR↑, 5,   mTOR↝, 1,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 5,   PI3K↑, 10,   PI3K↝, 1,   PKCδ↓, 2,   PKCδ↑, 2,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 1,   STAT↓, 2,   STAT3↓, 3,   STAT3↑, 3,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ac-histone H3↑, 1,   AntiThr↑, 7,   ATF2↑, 1,   ATF4↓, 3,   DNMT1↓, 1,   FOXO↑, 1,   FOXO3↑, 1,   H3↑, 1,   H4↑, 1,   HATs↓, 1,   HDAC↓, 3,   HDAC↑, 2,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 2,   HOTAIR↑, 1,   other?, 3,   other↓, 10,   other↑, 23,   other↝, 41,   PhotoS↑, 1,   SOX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 4,   CHOP/DDIT3↑, 1,   eIF2α↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 7,   GRP78/BiP↓, 4,   GRP78/BiP↑, 2,   GRP94↑, 1,   HSP70/HSPA5↑, 3,   HSP70/HSPA5↝, 1,   HSP90↑, 1,   HSPs↑, 2,   IRE1↓, 1,   PERK↓, 1,   UPR↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 5,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↓, 2,   LC3II↑, 1,   MitoP↓, 1,   p62↑, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   DNAdam↓, 13,   DNArepair↑, 3,   P53↓, 3,   PARP1↓, 1,   PCNA↓, 2,   Telomerase↓, 1,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   E2Fs↑, 1,   GADD34↓, 1,   Ki-67↓, 2,   Ki-67↑, 1,   P21↓, 1,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,   Choline↑, 2,   Diff↝, 1,   FGF↑, 1,   GH↑, 1,   HH↓, 1,   HMGCR↓, 1,   IGF-1↓, 1,   IGF-1↑, 1,   IGFBP3↑, 1,   Ki-67↓, 2,   Ki-67↑, 1,   Nestin↑, 1,   neuroG↑, 8,   NOTCH1↑, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 3,   AntiAg↑, 25,   AP-1↓, 7,   BACH1↓, 1,   Ca+2↓, 3,   Ca+2↑, 2,   Ca+2↝, 1,   Cartilage↑, 2,   COL1↓, 3,   Fibrosis↓, 1,   LRP1↑, 1,   MLC2/MYL9↝, 1,   MMP13↓, 2,   MMP2↓, 2,   MMP2↑, 2,   MMP3↓, 1,   MMP9↓, 10,   MMPs↓, 4,   MUC1↑, 1,   N-cadherin↑, 1,   Rho↓, 1,   ROCK1↓, 1,   p‑SMAD2↓, 2,   p‑SMAD3↓, 1,   p‑SMAD3↑, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 5,   TGF-β↑, 2,   TGF-β1↓, 2,   TGF-β1↑, 1,   TIMP1↓, 1,   TregCell↑, 1,   TXNIP↓, 1,   uPA↑, 1,   α-SMA↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 3,   CD31/PECAM-1↑, 1,   E-sel↓, 1,   NO↓, 20,   NO↑, 3,   TXA2↓, 2,   VCAM-1↓, 8,   VEGF↓, 2,   VEGF↑, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↓, 7,   BBB↑, 53,   BBB↝, 3,   BBB∅, 3,   EPR↑, 1,   GastroP↑, 6,   GLUT2↑, 2,   GLUT3↑, 1,   GLUT4↑, 3,   H+/K+-ATPase↓, 1,   IBI↑, 5,   memfluid↑, 2,   MMP↓, 1,   MMP↑, 16,   MMP∅, 1,   MUC19↓, 1,   MUC2↓, 1,   OCLN↓, 1,   OCLN↝, 1,   TJ↑, 3,   TRPA1↑, 1,   TRPV1↑, 2,   TRPV3↑, 2,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   CB2 / CNR2↑, 1,   CD4+↑, 2,   CD8+↑, 1,   COX1↓, 9,   COX2/PTGS2↓, 57,   COX2/PTGS2↑, 1,   CXCR4↓, 1,   HMGB1↓, 2,   ICAM-1↓, 5,   IFN-γ↓, 5,   IFN-γ↑, 1,   IL1↓, 5,   IL10↓, 5,   IL10↑, 6,   IL12↓, 2,   IL17↓, 4,   IL18↓, 3,   IL1α∅, 1,   IL1β↓, 47,   IL1β∅, 1,   IL2↓, 5,   IL22↓, 1,   IL33↓, 1,   IL4↓, 5,   IL4↑, 1,   IL5↓, 2,   IL6↓, 55,   IL6↑, 3,   IL8↓, 12,   IL8↑, 1,   IL8∅, 1,   Imm↓, 2,   Imm↑, 20,   Imm⇅, 1,   Imm↝, 2,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 216,   Inflam↑, 6,   IRF3↓, 1,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 5,   MCP1/CCL2↑, 1,   MCP1/CCL2∅, 1,   MCT1↓, 1,   MIP‑1α/CCL3↓, 1,   MyD88↓, 1,   NeuroI↓, 3,   NF-kB↓, 77,   NF-kB↑, 3,   p‑NF-kB↓, 1,   NLRP3↓, 14,   NLRP3↑, 2,   p65↓, 2,   PGE2↓, 19,   RAGE↓, 3,   RANTES↓, 1,   TLR2↓, 4,   TLR3↓, 1,   TLR4↓, 9,   TLR4↑, 1,   TNF-α↓, 79,   TNF-α↑, 2,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 6,   Ach↑, 6,   AChE↓, 30,   AChE↑, 2,   ADAM10↑, 3,   BChE↓, 9,   BDNF↓, 1,   BDNF↑, 19,   ChAT↑, 6,   GABA↑, 5,   MAOA↓, 6,   MAOA↝, 1,   MAOB↓, 2,   monoA↑, 1,   NGF↑, 6,   PSD95↑, 4,   SNAP25↑, 2,   TPH1↓, 1,   TrkB↑, 4,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 7,   APOE4↓, 1,   APP↓, 6,   cl‑APP↑, 1,   Aβ↓, 54,   Aβ42↓, 4,   BACE/β-secretase↓, 15,   PSEN1/PS1↑, 1,   tau↓, 16,   p‑tau↓, 7,   XO↓, 1,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   cortisol↑, 1,   CYP19↓, 2,   DHT↑, 1,   GLP-1R↑, 1,   GR↑, 1,   PPARα↑, 4,   PPARγ↓, 3,   PPARγ↑, 8,   p‑PPARγ↓, 1,   SHBG↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv?, 2,   BioAv↓, 210,   BioAv↑, 352,   BioAv⇅, 4,   BioAv↝, 171,   BioAv∅, 3,   BioEnh↑, 6,   ChemoSen↑, 4,   CompStab↓, 1,   CompStab↑, 10,   CompStab↝, 3,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 2,   CYP3A2↓, 1,   DDS↑, 1,   Dose?, 4,   Dose↑, 9,   Dose⇅, 2,   Dose↝, 117,   Dose∅, 4,   eff↓, 5,   eff↑, 58,   eff↝, 7,   GSTA1↓, 1,   GSTA1↑, 1,   Half-Life?, 2,   Half-Life↓, 34,   Half-Life↑, 19,   Half-Life↝, 58,   Half-Life∅, 6,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 7,   P450↓, 3,   P450↑, 2,   P450↝, 1,   Synergy↑, 34,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 18,   ALAT∅, 2,   ALB↑, 1,   ALP↓, 4,   anemia↓, 1,   AST↓, 20,   AST∅, 2,   BG↓, 2,   BloodF↑, 7,   BMD↑, 5,   BP↓, 17,   BP↝, 1,   p‑BRCA1↑, 1,   creat↓, 3,   CRP↓, 8,   Ferritin↓, 1,   Ferritin↑, 1,   HemoG↑, 1,   HOMA↓, 1,   hs-CRP↓, 3,   IL6↓, 55,   IL6↑, 3,   IRes↓, 1,   IRes↑, 2,   IRes↝, 1,   LDH↓, 6,   NOS2↓, 2,   RAGE↓, 3,   RBC↑, 1,   TC↓, 2,   TG/TAG↓, 2,   TMAO↓, 1,   Urea↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 5,   AntiAge↑, 12,   antiAll↑, 19,   AntiArt↑, 8,   AntiCan↓, 1,   AntiCan↑, 35,   antiCG↝, 1,   AntiDiabetic↓, 2,   AntiDiabetic↑, 48,   AntiMyl↑, 1,   antiPs↑, 4,   AntiTum↓, 2,   AntiTum↑, 6,   Appetite↓, 1,   cardioP↓, 2,   cardioP↑, 95,   cardioP⇅, 1,   CardioT↓, 2,   chemoP↑, 15,   chemoPv↑, 13,   cognitive↓, 2,   cognitive↑, 76,   cognitive↝, 1,   cognitive∅, 2,   cough?, 1,   diuretic↑, 3,   hepatoP↓, 3,   hepatoP↑, 67,   Learn↑, 5,   memory↓, 1,   memory↑, 60,   motorD↓, 1,   motorD↑, 10,   Mucositis↓, 2,   neuroP↓, 2,   neuroP↑, 168,   neuroP↝, 1,   Obesity↓, 26,   OS↑, 4,   Pain↓, 11,   radioP↑, 9,   RenoP↓, 1,   RenoP↑, 20,   RenoP↝, 1,   Risk↓, 6,   Risk↑, 3,   Sleep↑, 2,   SoreThr?, 1,   Strength↑, 2,   Stroke↓, 16,   toxicity?, 2,   toxicity↓, 75,   toxicity↑, 13,   toxicity⇅, 1,   toxicity↝, 27,   toxicity∅, 12,   Weight↓, 4,   Weight↝, 1,   Wound Healing↑, 8,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 20,   AntiFungal↑, 7,   AntiP↑, 1,   AntiViral↑, 16,   Bacteria↓, 40,   Diar↓, 2,   GutMicro↑, 40,   GutMicro↝, 2,   Sepsis↓, 4,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,   Ingr↑, 5,   Ingr↝, 8,  
Total Targets: 622

Scientific Paper Hit Count for: BioAv, bioavailability
49 Curcumin
21 Sulforaphane (mainly Broccoli)
20 chitosan
20 Quercetin
20 EGCG (Epigallocatechin Gallate)
18 Baicalein
18 Chlorogenic acid
17 Resveratrol
15 Berberine
15 Selenium NanoParticles
15 Chrysin
15 Luteolin
15 Lycopene
14 Apigenin (mainly Parsley)
14 Pterostilbene
13 Kaempferol
12 Thymoquinone
11 Silymarin (Milk Thistle) silibinin
11 Honokiol
10 Alpha-Lipoic-Acid
10 Rosmarinic acid
10 Magnolol
9 Astaxanthin
9 borneol
9 Carvacrol
9 Morin
9 Urolithin
8 Broccoli
8 Capsaicin
8 Crocetin
8 Diindolylmethane
8 Emodin
8 Ferulic acid
8 Fucoidan
8 Piperlongumine
7 Allicin (mainly Garlic)
7 Artemisinin
7 Betulinic acid
7 Hydroxycinnamic-acid
7 Piperine
7 Fisetin
7 Flaxseed/Linseed
7 HydroxyTyrosol
7 Isoliquiritigenin
7 isoquercitrin
7 Phenethyl isothiocyanate
6 Silver-NanoParticles
6 Ashwagandha(Withaferin A)
6 Biochanin A
6 Rutin
6 Propolis -bee glue
6 Ellagic acid
6 Eugenol
5 beta-glucans
5 Baicalin
5 Boswellia (frankincense)
5 Thymol-Thymus vulgaris
5 Centella asiatica / Gotu kola → asiaticoside
5 Cucurbitacin
5 Formononetin
5 SDG/lignans
5 Gallic acid
5 Inositol
5 Naringin
5 Selenite (Sodium)
4 1,8-Cineole
4 5-Hydroxytryptophan
4 Beta-Caryophyllene
4 Boron
4 Caffeic acid
4 Melatonin
4 Celastrol
4 phytic acid, Inositol hexakisphosphate
4 Garcinol
4 Isovitexin
4 Lactoferrin/Talactoferrin
4 Matrine
4 Phenylbutyrate
4 Vitamin C (Ascorbic Acid)
4 Shikonin
4 Aflavin-3,3′-digallate
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Berbamine
3 Folic Acid, Vit B9
3 Chocolate
3 Cinnamon
3 Coenzyme Q10
3 Copper and Cu NanoParticles
3 Diclofenac
3 Indole-3-carbinol
3 Disulfiram
3 Fenbendazole
3 Gambogic Acid
3 Genistein (soy isoflavone)
3 Glabrescione B
3 Gossypol/AT-101
3 Grapeseed extract
3 Lapatinib
3 Licochalcone A
3 Licorice
3 Lecithin
3 Linalool
3 Lutein
3 Methylene blue
3 mebendazole
3 Metformin
3 Magnetic Fields
3 Niclosamide (Niclocide)
3 Selenium
3 Silicic Acid
3 Spermidine
3 Terpinen-4-ol / Tea Tree Oil
2 3-bromopyruvate
2 Auranofin
2 Astragalus
2 Citric Acid
2 Aspirin
2 Paclitaxel/Taxol
2 Atorvastatin
2 immunotherapy
2 doxorubicin
2 Docetaxel
2 Radiotherapy/Radiation
2 buckwheat sprouts
2 Butyrate
2 Cynanbungeigenin C (CBC) and D (CBD)
2 Chlorophyllin
2 Choline
2 Camptothecin
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Dasatinib/Phyrago
2 Dichloroacetate
2 Deguelin
2 D-limonene
2 Evodiamine
2 flavonoids
2 MCT oil
2 Shilajit/Fulvic Acid
2 Geraniol
2 Ginkgolide B
2 Ginkgetin
2 Hydrogen Gas
2 HydroxyCitric Acid
2 isoflavones
2 isoorientin
2 itraconazole
2 Ivermectin
2 Lapachol
2 Lemongrass Extract/Citral
2 Methyl salicylate / Sweet Birch oil
2 magnetic nanoparticles
2 Magnesium
2 Mushroom Lion’s Mane, Hericium erinaceus
2 nicotinamide adenine dinucleotide
2 Oleuropein
2 Turmerones
2 Ursolic acid
1 Aluminum
1 Anethole/trans-Anethole
1 Aromatherapy
1 Gemcitabine (Gemzar)
1 Aloe anthraquinones
1 xanthohumol
1 beta-carotene(VitA)
1 Bicalutamide
1 Bacopa monnieri
1 α-Bisabolol / Chamomile oil
1 Bullatacin
1 Carnosic acid
1 urea
1 capecitabine
1 Catechins
1 Cat’s Claw
1 Cannabidiol
1 Zinc
1 Citicoline, CDP-Choline
1 irinotecan
1 Polyphenols
1 Cyclopamine
1 Dichloroacetophenone(2,2-)
1 Dandelion Root
1 Echinacea
1 Ginkgo biloba-EGb 761
1 Electrical Pulses
1 Eurycomanone
1 Sesame seeds and Oil
1 Mung Bean Sprouts
1 tamoxifen
1 Gamma-aminobutyric acid
1 Ginkgo biloba
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Geldanamycin
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Arsenic trioxide
1 Graviola
1 Germacranolide sesquiterpene lactone
1 Hibiscus sabdariffa
1 Hyperthermia
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Isobavachalcone
1 iodine
1 Anthocyanins
1 L-Theanine
1 Modified Citrus Pectin
1 Bicarbonate(Sodium)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 Cisplatin
1 Psoralidin
1 Parthenolide
1 enzalutamide
1 Rauwolfia serpentina/Indian Snakeroot
1 salinomycin
1 Chemotherapy
1 Date Fruit Extract
1 cetuximab
1 Tomatine
1 Vitamin B3,Niacin
1 Vitamin D3
1 Vitamin E
1 Vitamin K2
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:792  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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