EMT Cancer Research Results

EMT, Epithelial-Mesenchymal Transition: Click to Expand ⟱
Source:
Type:
Biological process in which epithelial cells lose their cell polarity and cell-cell adhesion properties and gain mesenchymal traits, such as increased motility and invasiveness. This process is pivotal during embryogenesis and wound healing. Hh signaling pathway is able to regulate the EMT. Snail, E-cadherin and N-cadherin, key components of EMT; EMT-related factors, E-cadherin, N-cadherin, vimentin; The hallmark of EMT is the upregulation of N-cadherin followed by the downregulation of E-cadherin.
EMT is regulated by various signaling pathways, including TGF-β, Wnt, Notch, and Hedgehog pathways. Transcription factors such as Snail, Slug, Twist, and ZEB play critical roles in repressing epithelial markers (like E-cadherin) and promoting mesenchymal markers (like N-cadherin and vimentin).
EMT is associated with increased tumor aggressiveness, enhanced migratory and invasive capabilities, and resistance to apoptosis.
Scientific Papers found: Click to Expand⟱
11- CUR,    Curcumin inhibits hypoxia-induced epithelial‑mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway
- in-vitro, PC, PANC1
HH↓, Shh↓, Smo↓, Gli1↓, N-cadherin↓, E-cadherin↑, Vim↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, chemoPv↑,
2688- CUR,    Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs
- Review, Var, NA - Review, AD, NA
*ROS↓, *SOD↑, p16↑, JAK2↓, STAT3↓, CXCL12↓, IL6↓, MMP2↓, MMP9↓, TGF-β↓, α-SMA↓, LAMs↓, DNAdam↑, *memory↑, *cognitive↑, *Inflam↓, *antiOx↑, *NO↑, *MDA↓, *ROS↓, DNMT1↓, ROS↑, Casp3↑, Apoptosis↑, miR-21↓, LC3II↓, ChemoSen↑, NF-kB↓, CSCs↓, Nanog↓, OCT4↓, SOX2↓, Synergy↑, Sp1/3/4↓, miR-27a-3p↓, ZBTB10↑, SOX9?, ChemoSen↑, VEGF↓, XIAP↓, Bcl-2↓, cycD1/CCND1↓, BioAv↑, Hif1a↓, EMT↓, BioAv↓, PTEN↑, VEGF↓, Akt↑, EZH2↓, NOTCH1↓, TP53↑, NQO1↑, HO-1↑,
2974- CUR,    Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29 - in-vitro, CRC, HCT15 - in-vitro, CRC, COLO205 - in-vitro, CRC, SW-620 - in-vivo, NA, NA
TumCMig↓, TumCI↓, TumCG↓, TumMeta↓, Sp1/3/4↓, HDAC4↓, FAK↓, CD24↓, E-cadherin↑, EMT↓, TumCP↓, NF-kB↓, AP-1↝, STAT3↓, P53?, β-catenin/ZEB1↓, NOTCH1↝, Hif1a↝, PPARα↝, Rho↓, MMP2↓, MMP9↓,
16- Cyc,  RES,    Resveratrol inhibits the hedgehog signaling pathway and epithelial-mesenchymal transition and suppresses gastric cancer invasion and metastasis
- in-vitro, GC, SGC-7901
HH↓, Gli1↓, EMT↓, N-cadherin↓, E-cadherin↑, Snail↓, TumCI↓, TumMeta↓,
6245- Cyc,    Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid Cancers
- vitro+vivo, PC, NA
HH↓, Snail↓, E-cadherin↑, EMT↓, TumCI↓, ChemoSen↑, TumMeta↓, ALDH↓, eff↑,
6248- Cyc,    The Hedgehog Inhibitor Cyclopamine Reduces β-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells
- in-vitro, CRC, NA
HH↓, Apoptosis↑, Slug↓, Snail↓, Twist↓, EMT↓, β-catenin/ZEB1↓, E-cadherin↑, TumCI↓,
4901- DCA,  Sal,    Dichloroacetate and Salinomycin as Therapeutic Agents in Cancer
- Review, NSCLC, NA
Glycolysis↓, OXPHOS↑, PDKs↓, ROS↑, Apoptosis↑, GlucoseCon↓, lactateProd↓, RadioS↑, TumAuto↑, mTOR↓, LC3s↓, p62↑, TumCG↓, OS↑, toxicity↝, ChemoSen↑, Synergy↑, Synergy↑, Ferritin↓, CSCs↓, EMT↓, ROS↑, Cyt‑c↑, Casp3↑, ER Stress↑, selectivity↑, Synergy↑, TumCG↓,
6676- Deg,    Deguelin’s Anticancer Bioactivity: Challenges and Opportunities in Medicinal Chemistry
- Review, Var, NA
TumCP↓, Apoptosis↑, NF-kB↓, Wnt↓, TumCCA↑, TumMeta↑, antiOx↑, Inflam↓, angioG↓, Half-Life↑, MMP2↓, MMP9↓, Casp9↑, Casp3↑, EMT↓, PTEN↑, ChemoSen↑, toxicity↑, *BBB↑,
19- Deg,    Deguelin inhibits proliferation and migration of human pancreatic cancer cells in vitro targeting hedgehog pathway
- in-vitro, PC, Bxpc-3 - in-vitro, PC, PANC1
HH↓, Gli1↓, PTCH1↓, Sufu↓, MMP2↓, MMP9↓, PI3K/Akt↓, HIF-1↓, VEGF↓, IKKα↓, NF-kB↓, EMT↓, AMPK↑, mTOR↓, survivin↓, TumCG↓, Apoptosis↑, TumCMig↓, TumCI↓,
1109- DHA,    DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells
- in-vitro, BC, NA
GREM1↓, TumCMig↓, p‑ERK↓, EMT↓,
8843- DIM,    3,3′-diindolylmethane induces ferroptosis and inhibits proliferation in non-small-cell lung cancer through the AHR/NRF2/GPX4 axis
- in-vitro, NSCLC, NA
tumCV↓, Apoptosis↑, TumCCA↑, TumCMig↓, TumCI↓, EMT↓, Ferroptosis↑, Iron↑, ROS↑, MDA↑, GSH↓, AhR↓, NRF2↓, GPx4↓, MMP↓, eff↓,
8852- DIM,    3,3'-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway
- in-vitro, ESCC, TE1 - in-vitro, ESCC, KYSE-30
AhR↓, TumCMig↓, TumCI↓, β-catenin/ZEB1↓, Vim↓, Slug↓, CLDN1↑, COX2/PTGS2↓, PGE2↓, ROCK1↓, ROCK1↓, EMT↓,
8851- DIM,    3,3’-Diindolylmethane and its derivatives: nature-inspired strategies tackling drug resistant tumors by regulation of signal transduction, transcription factors and microRNAs
- Review, Var, NA
Apoptosis↑, NF-kB↓, Akt↓, Wnt↓, PI3K↓, mTOR↓, PSA↓, Let-7↓, miR-34a↓, EZH2↓, NOTCH1↓, AR↓, E-cadherin↑, Zeb1↓, Vim↓, Slug↓, EMT↓, MTA2↓, NF-kB↓, IRAK1↓, EGFR↓, SOX4↓, FOXM1↓, p27/CDKN1B↓, AhR↓, EZH2↓, Wnt↓, PUMA↓, AEG1↑, ROS↑, PPARα↑, CycB/CCNB1↑,
8841- DIM,    3,3'-Diindolylmethane Suppresses the Growth of Hepatocellular Carcinoma by Regulating Its Invasion, Migration, and ER Stress-Mediated Mitochondrial Apoptosis
- in-vitro, Liver, Hep3B - in-vitro, Liver, HUH7
TumCG↓, TumCP↓, TumCMig↓, TumCI↓, Casp↑, EMT↓, UPR↓, Ca+2↑, ROS↑, MMP↓, ER Stress↑, CHOP/DDIT3↑, GRP78/BiP↑, IRE1↑, PERK↑, PDI↑, MMP2↓, MMP9↓, N-cadherin↓, Vim↓, Slug↓, Snail↓, chemoPv↑,
6348- DRE,    New prospects in oncotherapy: bioactive compounds from Taraxacum officinale
- Review, Var, NA
Ingr↝, TumCP↓, toxicity↓, *AntiDiabetic↑, *antiOx↑, *hepatoP↑, *diuretic↑, *Inflam↓, *neuroP↑, *Imm↑, eff↑, Apoptosis↑, tumCV↓, selectivity↑, TumCMig↓, EMT↓, MMP2↓, MMP9↓, Wnt↓, β-catenin/ZEB1↓, PI3K↓, Akt↓, JNK↓, ERK↓,
6360- DRE,    Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma
- in-vitro, ESCC, KYSE450 - in-vitro, ESCC, Eca109
TumCG↓, TumCP↓, TumCMig↓, TumCI↓, angioG↓, Apoptosis↑, PI3K↓, Akt↓, p‑Akt↓, survivin↓, Bax:Bcl2↑, Casp3↑, Casp9↑, MMP2↓, MMP9↓, VEGF↓, EMT↓, Synergy↑, DNAdam↑, p‑STAT3↑, ChemoSen↑,
4914- DSF,  immuno,    Disulfiram and cancer immunotherapy: Advanced nano-delivery systems and potential therapeutic strategies
- Review, Var, NA
AntiTum↑, eff↑, ALDH↓, Dose↝, RadioS↑, angioG↓, TumMeta↓, BioAv↝, ROS↑, DNAdam↑, P-gp/ABCB1↓, CSCs↓, EMT↓, Imm↑, SOD↓, MAPK↓, NF-kB↓, ChemoSen↑, Synergy↑, toxicity↝, BioAv↑, *Inflam↓, Sepsis↓,
5012- DSF,  Cu,    Advancing Cancer Therapy with Copper/Disulfiram Nanomedicines and Drug Delivery Systems
- Review, Var, NA
ROS↑, ALDH↓, TumCP↓, CSCs↓, angioG↓, TumMeta↓, DNAdam↑, Proteasome↓, SOD1↓, GSR↓, ox-GSSG↑, GSH/GSSG↓, MMP↓, Akt↓, cycD1/CCND1↓, NF-kB↓, CSCs↓, MAPK↓, angioG↓, DrugR↓, EMT↓, Vim↓, BioAv↑, eff↑,
1607- EA,    Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions
- Review, GC, NA
STAT3↓, TumCP↓, Apoptosis↑, NF-kB↓, EMT↓, RadioS↑, antiOx↑, COX1↓, COX2/PTGS2↓, cMyc↓, Snail↓, Twist↓, MMP2↓, P90RSK↓, CDK8↓, PI3K↓, Akt↓, TumCCA↑, Casp8↑, PCNA↓, TGF-β↓, Shh↓, NOTCH↓, IL6↓, ALAT↓, ALP↓, AST↓, VEGF↓, P21↑, *toxicity∅, *Inflam↓, *cardioP↑, *neuroP↑, *hepatoP↑, ROS↑, *NRF2↓, *GSH↑,
1621- EA,    The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art
- Review, Var, NA
AntiCan↑, Apoptosis↑, TumCP↓, TumMeta↓, TumCI↓, TumAuto↑, VEGFR2/KDR/Flk1↓, MAPK↓, PI3K↓, Akt↓, PD-1↓, NOTCH↓, PCNA↓, Ki-67↓, cycD1/CCND1↓, CDK2↑, CDK6↓, Bcl-2↓, cl‑PARP↑, BAX↑, Casp3↑, DR4↑, DR5↑, Snail↓, MMP2↓, MMP9↓, TGF-β↑, PKCδ↓, β-catenin/ZEB1↓, SIRT1↓, HO-1↓, ROS↑, CHOP/DDIT3↑, Cyt‑c↑, MMP↓, OCR↓, AMPK↑, Hif1a↓, NF-kB↓, E-cadherin↑, Vim↓, EMT↓, LC3II↑, CIP2A↓, GLUT1↓, PDH↝, MAD↓, LDH↓, GSTs↑, NOTCH↓, survivin↓, XIAP↓, ER Stress↑, ChemoSideEff↓, ChemoSen↑,
7193- EGb 761,  5-FU,    Ginkgo biloba extract 761 enhances 5-fluorouracil chemosensitivity in colorectal cancer cells through regulation of high mobility group-box 3 expression
- in-vitro, CRC, SW480 - in-vitro, CRC, SW-620
*antiOx↑, AntiCan↑, ChemoSen↑, selectivity↑, EMT↓, E-cadherin↑, Vim↓, HMGB1↓, other↝, chemoPv↑,
6784- EGCG,    Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *cardioP↑, *neuroP↑, *GutMicro↑, *AntiBio↑, *ROS↓, *TNF-α↓, *IL6↓, TumCP↓, *LDL↓, *NO↓, *Obesity↓, *p‑tau↓, *Aβ↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *NLRP3↓, *mTOR↓, TumCCA↑, NRF2↓, Apoptosis↑, SIRT1↓, miR-25-5p↓, PARP↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, EMT↓, TumCI↓, TumCMig↓, TGF-β↓, Smad1↓, STAT3↓, VEGF↓, angioG↓, Imm↑, EGFR↓, *GutMicro↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *BioAv↑, *Synergy↑, *BioAv↑, Synergy↑, ChemoSen↑, *toxicity↝,
4680- EGCG,    The Potential of Epigallocatechin Gallate in Targeting Cancer Stem Cells: A Comprehensive Review
- Review, Var, NA
CSCs↓, EMT↓, TumMeta↓, RadioS↑, ChemoSen↑, CompStab↓,
4682- EGCG,    Human cancer stem cells are a target for cancer prevention using (−)-epigallocatechin gallate
- Review, Var, NA
CSCs↓, EMT↓, ChemoSen↑, CD133↓, CD44↓, ALDH1A1↓, Nanog↓, OCT4↓, TumCP↓, Apoptosis↑, p‑GSK‐3β↓, GSK‐3β↑, β-catenin/ZEB1↓, cMyc↓, XIAP↓, Bcl-2↓, survivin↓, Vim↓, Slug↓, Snail↓,
4685- EGCG,    Epigallocathechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines
- in-vitro, NPC, TW01 - in-vitro, NPC, TW06
CSCs↓, EMT↓, TumCMig↓, TumCI↓, OCT4↓, Snail↓, Vim↓, E-cadherin↓, HSP70/HSPA5↓, HSP90↓, AntiTum↓,
22- EGCG,    Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
- in-vitro, PC, CD133+ - in-vitro, PC, CD44+ - in-vitro, PC, CD24+ - in-vitro, PC, ESA+
HH↓, Smo↓, PTCH1↓, PTCH2↓, Gli1↓, GLI2↓, Gli↓, Bcl-2↓, XIAP↓, Shh↓, survivin↓, Casp3↑, Casp7↑, CSCs↓, Nanog↓, cMyc↓, OCT4↓, EMT↓, Snail↓, Slug↓, Zeb1↓, TumCMig↓, TumCI↓, Synergy↑,
1072- EGCG,    Epigallocatechin gallate (EGCG) suppresses epithelial-Mesenchymal transition (EMT) and invasion in anaplastic thyroid carcinoma cells through blocking of TGF-β1/Smad signaling pathways
- in-vitro, Thyroid, 8505C
EMT↓, TumCI↓, TumCMig↓, TGF-β↓, p‑SMAD2↓, p‑SMAD3↓, SMAD4↓,
685- EGCG,  CUR,  SFN,  RES,  GEN  The “Big Five” Phytochemicals Targeting Cancer Stem Cells: Curcumin, EGCG, Sulforaphane, Resveratrol and Genistein
- Analysis, Var, NA
Bcl-2↓, survivin↓, XIAP↓, EMT↓, Apoptosis↑, Nanog↓, cMyc↓, OCT4↓, Snail↓, Slug↓, Zeb1↓, TCF↓,
6823- EMD,    Role of emodin to prevent gastrointestinal cancers: recent trends and future prospective
- Review, Var, NA
AntiCan↑, *antiOx↑, *chemoP↑, *Inflam↓, TumCP↓, TumMeta↓, TumCCA↑, MAPK↑, BAX↑, Casp↑, ROS↑, *BioAv↓, other↝, TumCI↓, EMT↓, TumCG↑, Apoptosis↑, TumCP↑, MMP2↓, Casp3↑, ChemoSen↑, PI3K↓, Akt↓, Cyt‑c↑, cl‑PARP↑, MMP↓, Warburg↓, HK2↓, PKM2↓, LDHA↓, mtDam↑, Apoptosis↑, N-cadherin↓, Vim↓, E-cadherin↑, eff↑, eff↑, eff↑, toxicity↝, toxicity↑,
6819- EMD,    Recent advances in the therapeutic potential of emodin for human health
- Review, Nor, NA
AntiCan↑, *AntiDiabetic↑, *neuroP↑, *Inflam↓, *antiOx↑, *BioAv↓, *BioAv↑, *SOD↑, *GPx↑, *GSH↑, *NRF2↑, *ROS↓, *lipid-P↓, *Cyt‑c↓, *BAX↓, *Bcl-2↓, *iNOS↓, *NO↓, *IL6↓, *IL10↓, *IL17↓, *IFN-γ↓, *NF-kB↓, *LC3II↓, *Akt↓, *Beclin-1/ATG6↓, *AMPK↓, *TNF-α↓, *PGE2↓, *Apoptosis↓, *Casp3↓, *Casp9↓, *P53↓, *P21↓, *NAD↓, *ATP↓, *CHOP/DDIT3↓, *GADD34↓, *ATF4↓, tumCV↓, Apoptosis↑, TumCG↓, TumCI↓, TumMeta↓, CSCs↓, NOTCH1↓, STAT3↓, Synergy↑, miR-34a↓, *neuroP↑, *BDNF↓, *hepatoP↑, *ALAT↓, *AST↓, TG/TAG↓, ROS↑, Slug↓, EMT↓, Glycolysis↓, ChemoSen↑, P-gp/ABCB1↓, Ki-67↓, PCNA↓, ER Stress↑, TRIB3↑, NF-kB↑, TumMeta↑, *Imm↓, *toxicity↝,
1322- EMD,    The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers
- Review, Var, NA
Apoptosis↑, TumCP↓, ROS↑, TumAuto↑, EMT↓, TGF-β↓, DNAdam↑, ER Stress↑, TumCCA↑, ATP↓, NF-kB↓, CYP1A1↑, STAC2↓, JAK↓, PI3K↓, Akt↓, MAPK↓, FASN↓, HER2/EBBR2↓, ChemoSen↑, Synergy↑, ChemoSen↑, angioG↓, VEGF↓, MMP2↓, eNOS↓, FOXD3↑, MMP9↓, TIMP1↑,
1247- EMD,    Emodin exerts antitumor effects in ovarian cancer cell lines by preventing the development of cancer stem cells via epithelial mesenchymal transition
- vitro+vivo, Ovarian, SKOV3 - in-vitro, Ovarian, A2780S
TumCP↓, TumCMig↓, TumCI↓, EMT↓, N-cadherin↓, Vim↓, E-cadherin↑, TumCG↓, CD133↓, OCT4↓, CSCs↓,
1246- EMD,    Emodin reduces Breast Cancer Lung Metastasis by suppressing Macrophage-induced Breast Cancer Cell Epithelial-mesenchymal transition and Cancer Stem Cell formation
- in-vivo, BC, NA
TGF-β↓, EMT↓, CSCs↓,
6580- EU,    Eurycomanone Blocks TGF-β1-Induced Epithelial-to-Mesenchymal Transition, Migration, and Invasion Pathways in Human Non-Small Cell Lung Cancer Cells by Targeting Smad and Non-Smad Signaling
- in-vitro, Lung, A549 - in-vitro, Lung, Calu-1
TumCMig↓, MMP2↓, EMT↓, E-cadherin↑, Akt↓, N-cadherin↓, TGF-β↓, Smad1↓,
6356- Eug,  Cin,    Investigating the Molecular Mechanisms of the Anticancer Effects of Eugenol and Cinnamaldehyde Against Colorectal Cancer (CRC) Cells In Vitro
- in-vitro, CRC, SW-620 - in-vitro, CRC, Caco-2 - in-vitro, Nor, NCM460
P21↑, ChemoSen↑, Casp3↑, IL4↓, IL8↓, ROS↑, NRF2↑, HO-1↑, EMT↓,
6390- Eug,    Molecular mechanisms of eugenol as an antitumour bioactive compound: A comprehensive review
- Review, Var, NA
TumCCA↑, angioG↓, TumMeta↓, tumCV↓, Casp3↑, Casp6↑, DFF45↑, PARP↑, ROS↑, Cyt‑c↑, MPT↑, *ROS↓, NF-kB↓, COX2/PTGS2↓, 5LO↓, EMT↓, Snail↓, E-cadherin↑, Vim↓, PI3K↓, Akt↓, mTORC2↓, TumAuto↑, FOXO3↓, Apoptosis↑, ChemoSen↑, RadioS↑, DNMT1↓, DNMT3A↓,
6391- Eug,  BCP,  5-FU,    Exploring Mechanism of Actions for Eugenol and Beta-Caryophyllene to Combat Colorectal Cancer Chemotherapy Using Network Pharmacology
- in-vitro, CRC, HCT116
Synergy↑, ChemoSen↑, HSP90↓, Dose↝, TumAuto↑, Apoptosis↑, PI3K↓, Akt↓, mTOR↓, JNK↓, p38↓, EMT↓,
6389- Eug,    Molecular Insights into the Management of Eugenol's Anticancer Action Against Colon Cancer: A Detailed Review
- Review, Colon, NA
Apoptosis↓, TumCCA↓, Inflam↓, TumMeta↓, BioAv↑, eff↓, Half-Life↓, *ROS↓, *RNS↓, *SOD↓, *Catalase↑, *GSTs↑, *MAOA↓, *neuroP↑, *DNAdam↓, Apoptosis↑, ROS↑, selectivity↑, MMP↓, Cyt‑c↓, Casp3↑, Casp9↑, TumCD↑, BAX↑, BAD↑, APAF1↑, Bcl-2↓, Bcl-xL↓, P53↑, cl‑PARP↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, CDK2↓, CDK4↓, P21↑, p27/CDKN1B↑, NF-kB↓, COX2/PTGS2↓, PGE2↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, MMPs↓, EMT↓, Snail↓, Slug↓, Zeb1↓, E-cadherin↑, ChemoSen↑, CompStab↑,
6330- Eug,    Molecular Mechanisms of Action of Eugenol in Cancer: Recent Trends and Advancement
- Review, Var, NA
TumCD↑, TumCCA↑, AntiCan↑, Apoptosis↑, angioG↓, TumCI↓, TumMeta↓, ChemoSen↑, ALDH↓, NF-kB↓, IL6↓, IL8↓, BAX↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, Bcl-2↓, MMP2↓, MMP9↓, EMT↓, N-cadherin↓, Snail↓, E-cadherin↑, SOX2↓, ROS↑, PCNA↓, MMP1↓, Cyt‑c↑, LDH↑, CSCs↓, OCT4↓, NOTCH1↓, EpCAM↓, CD44↓, HER2/EBBR2↓, VEGF↓, TIMP2↑, eff↑, Ca+2↑, TumVol↓, DNAdam↑, GSH↓, H2O2↑, lipid-P↑,
1111- EVO,    Evodiamine exerts inhibitory roles in non‑small cell lung cancer cell A549 and its sub‑population of stem‑like cells
- in-vitro, Lung, A549
TumCP↓, TumCMig↓, TumCI↓, EMT↓,
1654- FA,    Molecular mechanism of ferulic acid and its derivatives in tumor progression
- Review, Var, NA
AntiCan↑, Inflam↓, RadioS↑, ROS↑, Apoptosis↑, TumCCA↑, TumCMig↑, TumCI↓, angioG↓, ChemoSen↑, ChemoSideEff↓, P53↑, cycD1/CCND1↓, CDK4↓, CDK6↓, TumW↓, miR-34a↑, Bcl-2↓, Casp3↑, BAX↑, β-catenin/ZEB1↓, cMyc↓, Bax:Bcl2↑, SOD↓, GSH↓, LDH↓, ERK↑, Synergy↑, JAK2↓, STAT6↓, NF-kB↓, PYCR1↓, PI3K↓, Akt↓, mTOR↓, Ki-67↓, VEGF↓, FGFR1↓, EMT↓, CAIX/CA9↓, LC3II↑, p62↑, PKM2↓, Glycolysis↓, *BioAv↓,
1656- FA,    Ferulic Acid: A Natural Phenol That Inhibits Neoplastic Events through Modulation of Oncogenic Signaling
- Review, Var, NA
tyrosinase↓, CK2↓, TumCP↓, TumCMig↓, FGF↓, FGFR1↓, PI3K↓, Akt↓, VEGF↓, FGFR1↓, FGFR2↓, PDGF↓, ALAT↓, AST↓, TumCCA↑, CDK2↓, CDK4↓, CDK6↓, BAX↓, Bcl-2↓, MMP2↓, MMP9↓, P53↑, PARP↑, PUMA↑, NOXA↑, Casp3↑, Casp9↑, TIMP1↑, lipid-P↑, mtDam↑, EMT↓, Vim↓, E-cadherin↓, p‑STAT3↓, COX2/PTGS2↓, CDC25↓, RadioS↑, ROS↑, DNAdam↑, γH2AX↑, PTEN↑, LC3II↓, Beclin-1/ATG6↓, SOD↓, Catalase↓, GPx↓, Fas↑, *BioAv↓, cMyc↓, Beclin-1/ATG6↑, LC3‑Ⅱ/LC3‑Ⅰ↓,
1112- FA,    Ferulic acid exerts antitumor activity and inhibits metastasis in breast cancer cells by regulating epithelial to mesenchymal transition
- in-vitro, BC, MDA-MB-231 - in-vivo, BC, NA
tumCV↓, Apoptosis↑, AntiTum↑, TumMeta↓, EMT↓, TumVol↓, TumW↓,
6915- FIS,  SRF,    Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma
- in-vitro, Melanoma, NA
EMT↓, TumCP↓, PI3K↓, Synergy↑, N-cadherin↓, Vim↓, Fibronectin↓, E-cadherin↑, Snail↓, Twist↓, Slug↓, Zeb1↓, MMP2↓, MMP9↓, TumCI↓, TumMeta↓, ChemoSen↑,
2845- FIS,    Fisetin: A bioactive phytochemical with potential for cancer prevention and pharmacotherapy
- Review, Var, NA
PI3K↓, Akt↓, mTOR↓, p38↓, *antiOx↑, *neuroP↑, Casp3↑, Bcl-2↓, Mcl-1↓, BAX↑, BIM↑, BAD↑, AMPK↑, ACC↑, DNAdam↑, MMP↓, Synergy↑, ROS↑, cl‑PARP↑, Cyt‑c↑, Diablo↑, P53↑, p65↓, Myc↓, HSP70/HSPA5↓, HSP27↓, COX2/PTGS2↓, Wnt↓, EGFR↓, NF-kB↓, TumCCA↑, CDK2↓, CDK4↓, cycD1/CCND1↓, cycA1/CCNA1↓, P21↑, MMP2↓, MMP9↓, TumMeta↓, MMP1↓, MMP3↓, MMP7↓, MET↓, N-cadherin↓, Vim↓, Snail↓, Fibronectin↓, E-cadherin↑, uPA↓, ChemoSen↑, EMT↓, Twist↓, Zeb1↓, cFos↓, cJun↓, EGF↓, angioG↓, VEGF↓, eNOS↓, *NRF2↑, HO-1↑, NRF2↓, GSTs↓, ATF4↓,
2824- FIS,    Fisetin in Cancer: Attributes, Developmental Aspects, and Nanotherapeutics
- Review, Var, NA
*antiOx↑, *Inflam↓, angioG↓, BioAv↓, BioAv↑, TumCP↓, TumCI↓, TumCMig↓, *neuroP↑, EMT↓, ROS↑, selectivity↑, EGFR↓, NF-kB↓, VEGF↓, MMP9↓, MMP↓, cl‑PARP↑, Casp7↑, Casp8↑, Casp9↑, *ROS↓, uPA↓, MMP1↓, Wnt↓, Akt↓, PI3K↓, ERK↓, Half-Life↝,
2825- FIS,    Exploring the molecular targets of dietary flavonoid fisetin in cancer
- Review, Var, NA
*Inflam↓, *antiOx↓, *ERK↑, *p‑cMyc↑, *NRF2↑, *GSH↑, *HO-1↑, mTOR↓, PI3K↓, Akt↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, CDK6↓, P21↑, p27/CDKN1B↑, JNK↑, MMP2↓, MMP9↓, uPA↓, NF-kB↓, cFos↓, cJun↓, E-cadherin↑, Vim↓, N-cadherin↓, EMT↓, MMP↓, Cyt‑c↑, Diablo↑, Casp↑, cl‑PARP↑, P53↑, COX2/PTGS2↓, PGE2↓, HSP70/HSPA5↓, HSP27↓, DNAdam↑, Casp3↑, Casp9↑, ROS↑, AMPK↑, NO↑, Ca+2↑, mTORC1↓, p70S6↓, ROS↓, ER Stress↑, IRE1↑, ATF4↑, GRP78/BiP↑, Synergy↑, Synergy↑, Synergy↑, RadioS↑, ChemoSen↑, Half-Life↝,
2829- FIS,    Fisetin: An anticancer perspective
- Review, Var, NA
TumCP↓, TumCI↓, TumCCA↑, TumCG↓, Apoptosis↑, cl‑PARP↑, PKCδ↓, ROS↓, ERK↓, NF-kB↓, survivin↓, ROS↑, PI3K↓, Akt↓, mTOR↓, MAPK↓, p38↓, HER2/EBBR2↓, EMT↓, PTEN↑, HO-1↑, NRF2↑, MMP2↓, MMP9↓, MMP↓, Casp8↑, Casp9↑, TRAILR↑, Cyt‑c↑, XIAP↓, P53↑, CDK2↓, CDK4↓, CDC25↓, CDC2↓, VEGF↓, DNAdam↑, TET1↓, CHOP/DDIT3↑, CD44↓, CD133↓, uPA↓, CSCs↓,
2830- FIS,    Biological effects and mechanisms of fisetin in cancer: a promising anti-cancer agent
- Review, Var, NA
TumCG↓, angioG↓, *ROS↓, TumCMig↓, VEGF↓, MAPK↑, NF-kB↓, PI3K↓, Akt↓, mTOR↓, NRF2↑, HO-1↑, ROS↓, Inflam↓, ER Stress↑, ROS↑, TumCP↓, ChemoSen↑, PTEN↑, P53↑, Casp3↑, Casp8↑, Casp9↑, COX2/PTGS2↓, Wnt↓, EGFR↓, Mcl-1↓, survivin↓, IAP1↓, IAP2/BIRC3↓, PGE2↓, β-catenin/ZEB1↓, DR5↑, MMP2↓, MMP9↓, FAK↓, uPA↓, EMT↓, ERK↓, JNK↑, p38↑, PKCδ↓, BioAv↓, BioAv↑, BioAv↑,
2839- FIS,    Dietary flavonoid fisetin for cancer prevention and treatment
- Review, Var, NA
DNAdam↑, ROS↑, Apoptosis↑, Bcl-2↓, BAX↑, cl‑Casp9↑, cl‑Casp3↑, Cyt‑c↑, lipid-P↓, TumCG↓, TumCA↓, TumCMig↓, TumCI↓, uPA↓, ERK↓, MMP9↓, NF-kB↓, cFos↓, cJun↓, AP-1↓, TumCCA↑, AR↓, mTORC1↓, mTORC2↓, TSC2↑, EGF↓, TGF-β↓, EMT↓, P-gp/ABCB1↓, PI3K↓, Akt↓, mTOR↓, Synergy↑, ROS↓, ER Stress↑, IRE1↑, ATF4↑, GRP78/BiP↑, ChemoSen↑, CDK2↓, CDK4↓, cycE/CCNE↓, cycD1/CCND1↓, P21↑, COX2/PTGS2↓, Wnt↓, EGFR↓, β-catenin/ZEB1↓, TCF-4↓, MMP7↓, RadioS↑, Synergy↑,

Showing Research Papers: 101 to 150 of 366
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 366

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,   NA?, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 7,   Catalase↓, 7,   ENOX2↓, 1,   Fenton↑, 1,   frataxin↑, 1,   GPx↓, 3,   GPx1↓, 1,   GPx4↓, 8,   GPx4↝, 1,   GSH↓, 21,   GSH↑, 4,   GSH/GSSG↓, 1,   GSR↓, 2,   GSR↑, 1,   ox-GSSG↑, 1,   GSTs↓, 2,   GSTs↑, 1,   H2O2↑, 1,   HO-1↓, 8,   HO-1↑, 13,   Iron↑, 3,   c-Iron↑, 1,   Keap1↑, 1,   lipid-P↓, 2,   lipid-P↑, 8,   MDA↓, 1,   MDA↑, 4,   NQO1?, 1,   NQO1↓, 3,   NQO1↑, 4,   NRF2↓, 20,   NRF2↑, 14,   NRF2↝, 1,   PYCR1↓, 1,   RNS↑, 1,   ROS?, 1,   ROS↓, 20,   ROS↑, 140,   ROS⇅, 4,   ROS↝, 2,   i-ROS↓, 1,   mt-ROS↑, 2,   selenoP↑, 1,   SOD↓, 11,   SOD↑, 3,   SOD1↓, 3,   SOD1↑, 1,   SOD2↓, 4,   SOD2↑, 2,   Trx↓, 1,   Trx1↑, 1,   TrxR↓, 2,   TrxR1↓, 1,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 2,   IronCh↑, 1,   STEAP3↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

BCR-ABL↓, 1,   CDC2↓, 6,   CDC25↓, 6,   compI↓, 1,   compIII↓, 1,   compV↓, 1,   EGF↓, 6,   ETC↓, 3,   Insulin↓, 1,   mitResp↓, 4,   mitResp↑, 1,   Mortalin↓, 1,   mtDam↑, 13,   OCR↓, 4,   OXPHOS↓, 1,   OXPHOS↑, 2,   mt-OXPHOS↓, 1,   PDH↝, 1,   SIRT3↓, 1,   SIRT3↑, 4,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   5LO↓, 2,   AApath↓, 1,   ACADS/SCAD↓, 1,   ACC↑, 1,   ACLY↓, 1,   p‑ACLY↓, 1,   ACSL4↑, 1,   ALAT↓, 4,   AMPK↓, 1,   AMPK↑, 22,   AMPK↝, 1,   p‑AMPK↑, 1,   ATP↓, 15,   mt-ATP↓, 1,   CAIX/CA9↓, 1,   ECAR↓, 1,   ENO1↓, 1,   FABP4↑, 1,   FASN↓, 2,   GAPDH↓, 1,   glucoNG↓, 1,   glucose↓, 1,   glucose↝, 1,   GlucoseCon↓, 9,   GlutMet↓, 1,   Glycolysis↓, 27,   GSK‐3β↓, 9,   GSK‐3β↑, 2,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 8,   HK1↓, 1,   HK2↓, 11,   HMG-CoA↓, 4,   IDH1↑, 1,   lactateProd↓, 9,   LDHA↓, 4,   LDL↓, 1,   lipoGen↓, 1,   NAD↓, 1,   NADPH↓, 4,   NADPH↑, 1,   O-Glc↓, 1,   PDK1 / PDPK1↓, 5,   p‑PDK1 / PDPK1↓, 2,   PDK3↑, 1,   PDKs↓, 1,   PFK↓, 1,   PFK1↓, 1,   PIP3↑, 1,   PKM2↓, 15,   PKM2↑, 1,   RARα↓, 1,   RARβ↑, 1,   RARγ↑, 1,   SIRT1↓, 10,   SIRT1↑, 4,   SIRT2↓, 1,   SREBP1/SREBF1↓, 2,   TCA↓, 1,   Warburg↓, 5,  

Cell Death(tgid=5) ⓘ

AIF↑, 5,   APAF1↑, 3,   Apoptosis↓, 6,   Apoptosis↑, 124,   mt-Apoptosis↑, 1,   ASC↓, 1,   ASC↑, 1,   BAD↓, 1,   BAD↑, 3,   Bak↑, 7,   BAX↓, 1,   BAX↑, 59,   BAX↝, 1,   Bax:Bcl2↑, 16,   Bcl-2↓, 69,   Bcl-2↑, 1,   Bcl-xL↓, 18,   Bcl-xL↑, 1,   BID↑, 4,   p‑BID↓, 1,   BIM↓, 1,   BIM↑, 6,   BNIP3↑, 2,   BOK↑, 1,   Casp↑, 17,   Casp1↓, 3,   Casp10↑, 1,   Casp12↑, 1,   cl‑Casp12↑, 2,   cl‑Casp12↝, 1,   Casp3↓, 3,   Casp3↑, 71,   cl‑Casp3↑, 16,   Casp6↑, 1,   Casp7↑, 15,   Casp8↑, 14,   cl‑Casp8↑, 2,   Casp9↓, 1,   Casp9↑, 45,   cl‑Casp9↑, 5,   proCasp9↓, 1,   cFLIP↓, 2,   Cyt‑c↓, 2,   Cyt‑c↑, 42,   mt-Cyt‑c↓, 1,   Diablo↑, 4,   DR5↑, 19,   Endon↑, 1,   FADD↑, 4,   Fas↓, 1,   Fas↑, 15,   FasL↓, 1,   FasL↑, 4,   Ferroptosis↑, 13,   GSDMD↑, 1,   HEY1↓, 1,   IAP1↓, 5,   IAP2/BIRC3↓, 1,   IAP2/BIRC3↑, 1,   iNOS↓, 5,   Mcl-1?, 1,   Mcl-1↓, 15,   Mcl-1↑, 1,   p‑Mcl-1↓, 1,   MDM2↓, 7,   MDM2↑, 2,   p‑MDM2↓, 1,   NAIP↓, 1,   Necroptosis↑, 1,   NOXA↑, 1,   p38↓, 5,   p38↑, 9,   p‑p38↓, 2,   p‑p38↑, 1,   PUMA↓, 1,   PUMA↑, 2,   Pyro↑, 2,   RIP1↑, 1,   RIP3↑, 1,   survivin↓, 32,   TNFR 1↑, 1,   TRAIL↑, 1,   TRAIL⇅, 1,   TRAILR↑, 3,   TumCD↓, 1,   TumCD↑, 5,   TUNEL↑, 1,   XIAP↓, 19,   YAP/TEAD↓, 4,   YAP/TEAD↝, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 109,   Akt↑, 4,   Akt↝, 1,   p‑Akt↓, 30,   AKT1↓, 2,   Akt2↓, 1,   CIP2A↓, 1,   CK2↓, 3,   cMET↓, 3,   cSrc↓, 1,   DDIT4↑, 1,   EF-1α↓, 1,   EGFR↓, 31,   EGFR↑, 1,   p‑EGFR↓, 1,   ERK↓, 28,   ERK↑, 7,   ERK↝, 1,   p‑ERK↓, 10,   ERK5↑, 1,   FGFR1↓, 4,   FGFR2↓, 1,   FOXD3↑, 1,   HER2/EBBR2↓, 7,   p‑HER2/EBBR2↓, 1,   HGF/c-Met↓, 1,   Hippo↑, 1,   Hippo↝, 1,   IGF-1R↓, 1,   IKKα↓, 7,   IKKα↑, 1,   p‑IKKα↓, 1,   IκB↓, 1,   p‑IκB↓, 1,   JAK↓, 3,   p‑JAK↓, 1,   JAK1↓, 2,   JAK1↑, 1,   JAK2↓, 6,   p‑JAK2↓, 3,   p‑JAK3↓, 1,   JNK↓, 5,   JNK↑, 12,   JNK↝, 1,   p‑JNK↓, 1,   p‑JNK↑, 1,   LIMK1↓, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 28,   MAPK↑, 9,   MAPK↝, 1,   p‑MAPK↓, 1,   MARK4↓, 1,   MEK↓, 4,   MKK4↓, 1,   mTOR↓, 63,   mTOR↝, 1,   p‑mTOR↓, 6,   mTORC2↓, 2,   p70S6↓, 1,   P70S6K↓, 2,   P90RSK↓, 2,   PDGFR-BB↓, 1,   PDGFRA↓, 1,   PI3K↓, 94,   PI3K↝, 1,   p‑PI3K↓, 7,   PI3K/Akt↓, 4,   PI3k/Akt/mTOR↓, 1,   PKA↓, 1,   PKCδ↓, 5,   PTEN↓, 2,   PTEN↑, 19,   Raf↓, 4,   c-Raf↓, 1,   RAS↓, 4,   RET↓, 1,   p‑S6K↓, 1,   SHP1↑, 1,   Sp1/3/4↓, 12,   Src↓, 3,   p‑Src↓, 1,   STAT↓, 2,   p‑STAT2↓, 1,   STAT3↓, 54,   STAT3↑, 1,   STAT3↝, 1,   p‑STAT3↓, 12,   p‑STAT3↑, 2,   STAT6↓, 1,   p‑STAT6↓, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↓, 1,   ATF4↑, 10,   p‑ATF4↝, 1,   CBP↓, 1,   cJun↓, 7,   cJun↑, 1,   cMyc↓, 29,   p‑cMyc↑, 1,   DNMT1↓, 8,   DNMT3A↓, 5,   DNMTs↓, 2,   EZH2↓, 6,   FOXM1↓, 3,   FOXO1↓, 3,   FOXO3↓, 2,   FOXO3↑, 4,   p‑FOXO3↓, 1,   FOXO4↓, 2,   H3↓, 2,   H3↑, 2,   ac‑H3↑, 2,   H3K27ac↓, 1,   H4↓, 1,   H4↑, 1,   ac‑H4↑, 1,   HATs↓, 2,   HATs↑, 3,   HDAC↓, 14,   HDAC1↓, 3,   HDAC10↓, 1,   HDAC2↓, 2,   HDAC3↓, 2,   HDAC4↓, 2,   HES1↓, 3,   HOTAIR↓, 1,   miR-107↑, 1,   miR-10a-5p↝, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 1,   miR-141↑, 1,   miR-145↑, 1,   miR-155↓, 1,   miR-155↝, 1,   miR-19b↓, 1,   miR-200b↑, 1,   miR-200c↑, 1,   miR-203↑, 1,   miR-205↑, 1,   miR-21↓, 4,   miR-21↑, 1,   miR-218↑, 1,   miR-224↓, 1,   miR-25-5p↓, 1,   miR-27a-3p↓, 1,   miR-29b↑, 1,   miR-301a-3p↓, 1,   miR-339-5p↝, 1,   miR-340↓, 1,   miR-34a↓, 3,   miR-34a↑, 4,   miR-34a↝, 1,   miR-34b-5p↑, 1,   miR-384↑, 2,   miR-422a↑, 1,   MTA2↓, 1,   Myc↓, 2,   n-MYC↓, 1,   NDRG1↑, 1,   OCT4↓, 18,   other↓, 3,   other↑, 4,   other↝, 6,   PAX2↓, 1,   PhotoS↑, 1,   SOX2↓, 9,   SOX4↓, 4,   SOX9?, 1,   SOX9↓, 1,   TCF-4↓, 2,   TFE3↑, 1,   tumCV↓, 31,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 16,   p‑CHOP/DDIT3↝, 1,   cl‑CHOP/DDIT3↑, 1,   eIF2α↓, 1,   eIF2α↑, 3,   p‑eIF2α↑, 4,   p‑eIF2α↝, 1,   ER Stress↑, 32,   GRP78/BiP↓, 2,   GRP78/BiP↑, 12,   HSF1↓, 1,   HSP27↓, 6,   HSP70/HSPA5↓, 5,   HSP70/HSPA5↑, 1,   HSP90↓, 11,   IRE1↑, 5,   PDI↑, 1,   PERK↑, 7,   p‑PERK↝, 1,   Proteasome↓, 1,   SERPINH1/HSP47↓, 1,   UPR↓, 1,   UPR↑, 3,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   ATG7↑, 1,   Beclin-1/ATG6↓, 2,   Beclin-1/ATG6↑, 9,   CTSB↓, 2,   CTSD↓, 2,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3B-II↑, 2,   LC3II↓, 2,   LC3II↑, 10,   LC3s↓, 1,   lysoMP↑, 1,   p62↓, 3,   p62↑, 2,   SESN2↑, 1,   TumAuto↑, 28,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 2,   BRCA1↑, 1,   BRCA1↝, 1,   p‑BRCA1↑, 1,   DFF45↓, 1,   DFF45↑, 2,   DNAdam↑, 33,   DNArepair↓, 1,   ERCC1↓, 1,   ERCC3↑, 1,   m-FAM72A↓, 1,   hTERT/TERT↓, 9,   MGMT↓, 1,   p16↑, 2,   P53?, 1,   P53↓, 1,   P53↑, 55,   P53↝, 1,   p‑P53↑, 1,   ac‑P53↑, 1,   p53 Wildtype↑, 1,   p53 Wildtype∅, 1,   PARP↓, 1,   PARP↑, 15,   cl‑PARP↑, 25,   PARP1↑, 2,   PCNA↓, 21,   PCNA↑, 1,   POLD1↓, 1,   SIRT6↓, 1,   Telomerase↓, 9,   TOP1?, 1,   TOP1↓, 6,   TOP2↓, 4,   TP53↑, 2,   TRF2↓, 1,   XRCC1↓, 1,   γH2AX↑, 7,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 9,   CDK1↑, 1,   CDK2↓, 25,   CDK2↑, 2,   CDK4↓, 29,   CDK4↑, 1,   p‑CDK4↓, 1,   CDK6↓, 10,   CDK6↑, 1,   CDK8↓, 1,   CDKN1C/p57↑, 1,   CHK1↓, 1,   p‑CHK1↑, 1,   Chk2↓, 1,   p‑Chk2↑, 1,   cycA1/CCNA1↓, 3,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 14,   CycB/CCNB1↑, 2,   cycD1/CCND1↓, 48,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   cycE/CCNE↓, 9,   E2Fs↓, 1,   Ki-67↓, 22,   MAD↓, 1,   P21?, 1,   P21↓, 3,   P21↑, 33,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 14,   pRB↓, 1,   p‑pRB↓, 2,   RB1↓, 1,   RB1↑, 2,   p‑RB1↓, 3,   TumCCA↓, 4,   TumCCA↑, 105,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 7,   ALDH1A1↓, 6,   AXIN1↓, 1,   AXIN1↑, 1,   BMI1↓, 1,   BMP2↓, 1,   BMPs↑, 1,   CD133↓, 15,   CD133↑, 1,   CD24↓, 1,   CD34↓, 1,   CDX2↓, 1,   CEBPB↓, 1,   cFos↓, 7,   cFos↑, 1,   cMYB↓, 1,   CSCs↓, 69,   CSCsMark↓, 2,   Diff↓, 2,   Diff↑, 1,   EIF4E↓, 1,   FGF↓, 2,   FGF↑, 1,   Gli↓, 1,   Gli1↓, 13,   GREM1↓, 1,   HH↓, 15,   HH↝, 1,   IGF-1↓, 1,   IGF-2↓, 1,   IGFBP3↓, 1,   IGFBP3↑, 2,   Ki-67↓, 22,   Let-7↓, 1,   Let-7↑, 2,   LRP6↓, 3,   p‑LRP6↓, 1,   MSCmark↓, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 17,   Nestin↓, 3,   NICD↓, 1,   NKD2↑, 1,   NOTCH↓, 18,   NOTCH↑, 1,   NOTCH1↓, 18,   NOTCH1↑, 3,   NOTCH1↝, 1,   NOTCH3↓, 3,   p300↓, 2,   Pirin↓, 1,   PTCH1↓, 4,   PTCH2↓, 1,   SFRP5↑, 1,   Shh↓, 13,   Smo↓, 6,   p‑STAT1↓, 1,   Sufu↓, 1,   TAZ↓, 1,   TOPflash↓, 1,   TumCG?, 2,   TumCG↓, 62,   TumCG↑, 2,   TumCP?, 1,   TumCP↓, 112,   TumCP↑, 3,   tyrosinase↓, 1,   WDR72↓, 1,   Wnt↓, 44,   Wnt/(β-catenin)↓, 7,  

Migration(tgid=13) ⓘ

ACTA2↓, 1,   AEG1↓, 2,   AEG1↑, 1,   annexin II↓, 1,   AntiAg↓, 1,   AntiAg↑, 1,   AP-1↓, 7,   AP-1↝, 1,   AXL↓, 2,   CA↓, 1,   Ca+2↓, 1,   Ca+2↑, 21,   Ca+2↝, 2,   i-Ca+2↑, 1,   CAFs/TAFs↓, 2,   cal2↑, 1,   Cdc42↓, 1,   Chl↑, 1,   Cofilin↓, 1,   COL1↓, 1,   COL1A1↓, 1,   COL3A1↓, 1,   CTNNB1↓, 1,   E-cadherin↓, 19,   E-cadherin↑, 123,   EM↑, 2,   EMT?, 1,   EMT↓, 349,   EMT↑, 7,   EMT↝, 2,   EpCAM↓, 1,   F-actin↓, 2,   F-actin↑, 1,   FAK↓, 16,   FAK↑, 1,   p‑FAK↓, 3,   fascin↓, 1,   Fibronectin↓, 11,   Galectin-9↓, 1,   GIT1↓, 1,   GLI2↓, 3,   IQGAP3↓, 1,   ITGA5↓, 2,   ITGA5↑, 1,   ITGB1↓, 7,   ITGB1↑, 1,   ITGB3↓, 1,   ITGB6↓, 1,   LAMA5↑, 1,   LAMs↓, 2,   LEF1↓, 4,   MALAT1↓, 4,   MET↓, 2,   MET↑, 1,   p‑MET↓, 2,   MMP-10↓, 2,   MMP1↓, 4,   MMP13↓, 3,   MMP16↓, 2,   MMP2↓, 97,   MMP2↝, 1,   MMP3↓, 6,   MMP7↓, 7,   MMP9↓, 99,   MMP9↑, 2,   MMP9↝, 1,   MMPs↓, 28,   MUC1↑, 1,   MUC4↓, 1,   N-cadherin↓, 87,   PAK1↓, 1,   p‑pax↓, 1,   PDGF↓, 5,   PIR↓, 1,   Rac1↓, 3,   RHBDD1↓, 1,   Rho↓, 6,   ROCK1↓, 9,   Slug?, 1,   Slug↓, 41,   Smad1↓, 4,   Smad1↝, 1,   SMAD2↓, 5,   p‑SMAD2↓, 10,   SMAD3↓, 7,   p‑SMAD3↓, 8,   SMAD4↓, 2,   Snail?, 2,   Snail↓, 75,   Snail↑, 2,   STAC2↓, 1,   TET1↓, 1,   TET1↑, 3,   TGF-β↓, 31,   TGF-β↑, 1,   TGF-β↝, 1,   TGF-β1↓, 3,   TIMP1↑, 6,   TIMP2↓, 2,   TIMP2↑, 2,   TRIB3↑, 2,   TSP-1↑, 4,   TumCA↓, 2,   TumCI↓, 128,   TumCI↑, 3,   TumCMig↓, 129,   TumCMig↑, 3,   TumMeta↓, 77,   TumMeta↑, 5,   Twist↓, 30,   Twist↑, 2,   Tyro3↓, 1,   uPA↓, 22,   uPAR↓, 2,   Vim?, 1,   Vim↓, 103,   Vim↑, 3,   Zeb1↓, 32,   Zeb1↑, 2,   ZEB2↓, 2,   ZEB2↑, 2,   α-SMA↓, 3,   α-SMA↑, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 65,   β-catenin/ZEB1↑, 2,   p‑β-catenin/ZEB1↓, 1,   cl‑β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 64,   angioG↑, 2,   CD31/PECAM-1↓, 3,   eNOS↓, 3,   HIF-1↓, 5,   Hif1a↓, 49,   Hif1a↑, 1,   Hif1a↝, 1,   NO↓, 1,   NO↑, 1,   NO↝, 1,   TXA2↓, 1,   VEGF↓, 76,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 14,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 4,   CLDN1↓, 6,   CLDN1↑, 1,   CLDN2↓, 1,   CLDN7↑, 1,   EPR↑, 1,   GLUT1↓, 6,   GLUT2↓, 1,   MMP↓, 62,   MMP↑, 1,   MPT↑, 4,   NHE1↓, 1,   TRPV2↑, 1,   ZO-1↓, 1,   ZO-1↑, 6,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD25+↓, 1,   CD4+↓, 2,   CD4+↑, 1,   CD44↓, 18,   CD8+↑, 4,   COX1↓, 2,   COX2/PTGS2↓, 47,   COX2/PTGS2↑, 1,   COX2/PTGS2↝, 1,   CXCL12↓, 4,   CXCL16↓, 1,   CXCR4↓, 10,   DR4↑, 3,   FOXP3↑, 1,   FoxP3+↓, 1,   HMGB1↓, 6,   ICAM-1↓, 2,   IFN-γ↓, 2,   IFN-γ↑, 2,   Igs↑, 1,   IL1↓, 4,   IL10↓, 4,   IL12↓, 1,   IL12↑, 1,   IL18↓, 2,   IL1β↓, 13,   IL2↓, 2,   IL2↑, 4,   IL4↓, 2,   IL6↓, 32,   IL6↑, 1,   IL8↓, 7,   Imm↑, 9,   Imm↝, 3,   Inflam↓, 22,   IRAK1↓, 1,   M2 MC↓, 2,   MCP1/CCL2↓, 4,   MCT1↓, 1,   MDSCs↓, 1,   NF-kB↓, 101,   NF-kB↑, 4,   NF-kB↝, 1,   p‑NF-kB↓, 2,   p‑NF-kB↑, 2,   NK cell↑, 3,   NLRP3↓, 3,   p50↓, 1,   p65↓, 6,   p65↑, 1,   p‑p65↓, 5,   PD-1↓, 4,   PD-L1↓, 9,   PD-L2↓, 1,   PGE2↓, 19,   PSA↓, 4,   RAGE↓, 1,   SOCS-3↓, 1,   T-Cell↑, 1,   TCF↓, 5,   TCF7/TCF1↓, 2,   Th1 response↑, 1,   TILs↑, 1,   TIM-3↓, 1,   TLR4↓, 3,   TNF-α↓, 23,   TNF-α↑, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GGT/CD224↓, 1,   IM↓, 1,   pH↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

MAOA↓, 1,   PTN↓, 1,  

Protein Aggregation(tgid=19) ⓘ

PSEN1/PS1↓, 1,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AhR↓, 2,   AR↓, 12,   ER-α36↓, 1,   ER-α36↝, 1,   FGF21↓, 1,   PPARα↓, 1,   PPARα↑, 2,   PPARα↝, 1,   PPARγ↓, 3,   PPARγ↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

AKR1B10↓, 1,   BioAv↓, 26,   BioAv↑, 26,   BioAv↝, 7,   ChemoSen↓, 1,   ChemoSen↑, 111,   ChemoSen⇅, 1,   CompStab↓, 2,   CompStab↑, 2,   CompStab↝, 1,   CYP1A1↓, 2,   CYP1A1↑, 2,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   CYP2E1↑, 1,   CYP3A4↓, 1,   Dose?, 1,   Dose↓, 3,   Dose↑, 4,   Dose↝, 19,   Dose∅, 6,   DrugR↓, 1,   eff↓, 15,   eff↑, 38,   eff↝, 6,   eff∅, 2,   GSTA1↓, 1,   GSTA1↑, 1,   Half-Life↓, 8,   Half-Life↑, 1,   Half-Life↝, 7,   Half-Life∅, 1,   MDR1↓, 7,   MRP1/ABCC1↓, 2,   MRP1/ABCC1↝, 1,   P-gp/ABCB1↓, 15,   P450↓, 4,   RadioS↑, 37,   selectivity?, 1,   selectivity↑, 38,   Synergy↑, 83,  

Clinical Biomarkers(tgid=22) ⓘ

AFP?, 1,   ALAT↓, 4,   ALB↑, 1,   ALP↓, 3,   AR↓, 12,   AST?, 1,   AST↓, 2,   BRCA1↑, 1,   BRCA1↝, 1,   p‑BRCA1↑, 1,   CA125↓, 1,   CEA↓, 1,   CRP↓, 2,   DBIL↓, 1,   E6↓, 3,   E7↓, 3,   EGFR↓, 31,   EGFR↑, 1,   p‑EGFR↓, 1,   EZH2↓, 6,   Ferritin↓, 2,   FOXM1↓, 3,   HER2/EBBR2↓, 7,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 9,   IBIL↓, 1,   IL6↓, 32,   IL6↑, 1,   IRes↓, 1,   LDH↓, 5,   LDH↑, 3,   Maspin↑, 1,   Myc↓, 2,   NOS2↓, 1,   NSE↓, 1,   PD-L1↓, 9,   PSA↓, 4,   RAGE↓, 1,   TBIL↓, 1,   TG/TAG↓, 1,   TP53↑, 2,   TRIB3↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 24,   antiNeop↑, 1,   AntiTum↓, 2,   AntiTum↑, 15,   cachexia↓, 2,   cardioP↑, 6,   chemoP?, 1,   chemoP↑, 11,   chemoPv↑, 10,   ChemoSideEff↓, 4,   fatigue↓, 1,   hepatoP↑, 6,   neuroP↑, 5,   OS↑, 12,   Pain↓, 1,   PFS↑, 1,   Pin1↓, 2,   QoL↑, 3,   radioP↑, 2,   RenoP↑, 4,   Risk↓, 6,   Symptoms∅, 1,   toxicity?, 1,   toxicity↓, 8,   toxicity↑, 4,   toxicity↝, 7,   toxicity∅, 2,   TumVol↓, 15,   TumW↓, 6,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   GutMicro↑, 2,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 2,  
Total Targets: 958

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 43,   Catalase↑, 18,   DPPH↓, 1,   GPx↓, 1,   GPx↑, 13,   GPx1↑, 1,   GPx4↑, 1,   GSH↑, 16,   GSR↑, 2,   GSTs↑, 7,   HDL↓, 1,   HDL↑, 1,   HO-1?, 1,   HO-1↑, 8,   i-Iron↓, 1,   Keap1↓, 1,   lipid-P↓, 11,   MDA↓, 13,   MDA↑, 1,   MPO↓, 2,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 20,   Prx↑, 1,   RNS↓, 1,   ROS?, 1,   ROS↓, 56,   SOD↓, 1,   SOD↑, 18,   SOD1↑, 2,   SOD2↑, 2,   TAC↑, 1,   TrxR↑, 1,   uricA↓, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   ALAT↓, 6,   AMPK↓, 1,   AMPK↑, 3,   ATP↓, 1,   DGAT1↓, 1,   FASN↓, 1,   glucose↓, 2,   GlucoseCon↑, 1,   GSK‐3β↓, 1,   LDHA↑, 1,   LDL↓, 2,   lipidLev↓, 1,   NAD↓, 1,   NAD↑, 1,   PKM2↓, 1,   PLA2↓, 1,   SIRT1↑, 4,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   BAX↓, 2,   Bcl-2↓, 1,   Casp↓, 1,   Casp3?, 1,   Casp3↓, 4,   Casp9↓, 2,   Cyt‑c↓, 2,   Ferroptosis↓, 1,   iNOS↓, 4,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   Akt↑, 4,   Akt↝, 1,   p‑Akt↓, 1,   ERK↑, 1,   p‑ERK↓, 1,   JNK↓, 1,   JNK↑, 1,   MAPK↓, 1,   mTOR↓, 1,   mTOR↑, 2,   p‑mTOR↓, 1,   p‑P70S6K↓, 1,   PI3K↓, 1,   PI3K↑, 4,   PTEN↑, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   ATF4↓, 1,   p‑cMyc↑, 1,   HDAC↓, 1,   HDAC3↓, 1,   other↝, 2,   RUNX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 1,   HSP70/HSPA5↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 4,   LC3II↓, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   P53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

GADD34↓, 1,   Ki-67↓, 1,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   Ki-67↓, 1,   tyrosinase↓, 1,  

Migration(tgid=13) ⓘ

Ca+2↓, 1,   COL1↓, 3,   COL1↑, 1,   COL3A1↓, 1,   E-cadherin↑, 4,   EMT↓, 7,   EMT↑, 2,   Fibronectin↓, 1,   MMP13↓, 2,   MMP2↓, 1,   MMP9↓, 2,   Smad7↑, 2,   Snail↑, 1,   TGF-β↓, 3,   TGF-β1↓, 1,   TIMP1↓, 1,   TregCell↑, 1,   Twist↑, 1,   Vim↓, 4,   Vim↑, 1,   α-SMA↓, 6,   β-catenin/ZEB1↓, 1,   β-catenin/ZEB1↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   Hif1a↓, 2,   NO↓, 4,   NO↑, 1,   VEGF↓, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   GLUT2↑, 1,   GLUT3↑, 1,   GLUT4↑, 1,   MMP↑, 3,   TRPC1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 10,   HMGB1↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 3,   IFN-γ↑, 1,   IL10↓, 3,   IL10↑, 1,   IL17↓, 3,   IL18↓, 1,   IL1β↓, 12,   IL2↓, 1,   IL2↑, 1,   IL23↓, 1,   IL4↓, 1,   IL4↑, 1,   IL5↓, 2,   IL6↓, 14,   IL8↓, 3,   Imm↓, 1,   Imm↑, 3,   Inflam?, 2,   Inflam↓, 43,   IRF3↓, 1,   LPS↓, 1,   MCP1/CCL2↓, 1,   MyD88↓, 1,   NF-kB↓, 17,   NLRP3↓, 2,   PGE2↓, 8,   RAGE↓, 1,   SOCS-3↓, 1,   TLR2↓, 1,   TLR4↓, 5,   TNF-α↓, 17,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 4,   BDNF↓, 1,   BDNF↑, 1,   GABA↑, 1,   MAOA↓, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   Aβ↓, 9,   BACE/β-secretase↓, 2,   p‑tau↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   BNP↓, 1,   PPARα↝, 1,   p‑PPARγ↓, 1,   TSHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 24,   BioAv↑, 8,   BioAv↝, 3,   CYP2E1↓, 1,   Dose↑, 1,   Dose↝, 3,   eff↑, 3,   GSTA1↑, 1,   Half-Life↝, 6,   Half-Life∅, 1,   P450↓, 1,   Synergy↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 6,   AST↓, 7,   BMD↑, 1,   BP↓, 1,   BUN↓, 1,   creat↓, 1,   CRP↓, 2,   IL6↓, 14,   LDH↓, 2,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   antiAll↑, 5,   AntiArt↑, 2,   AntiCan↑, 5,   AntiDiabetic↑, 10,   AntiTum↓, 1,   AntiTum↑, 1,   cardioP↑, 19,   chemoP↑, 2,   chemoPv↑, 5,   cognitive↑, 4,   diuretic↑, 1,   hepatoP↑, 19,   Learn↑, 1,   memory↑, 6,   motorD↑, 1,   Mucositis↓, 2,   neuroP↑, 34,   Obesity↓, 2,   PDE4↓, 1,   radioP↑, 2,   RenoP↑, 5,   Stroke↓, 2,   toxicity↓, 15,   toxicity↑, 1,   toxicity↝, 4,   toxicity∅, 2,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 2,   AntiFungal↑, 1,   AntiViral↑, 2,   Bacteria↓, 4,   GutMicro↑, 5,   GutMicro↝, 1,   Sepsis↓, 2,  
Total Targets: 244

Scientific Paper Hit Count for: EMT, Epithelial-Mesenchymal Transition
19 Curcumin
17 Resveratrol
16 Quercetin
13 Honokiol
13 Luteolin
10 Sulforaphane (mainly Broccoli)
9 Ashwagandha(Withaferin A)
9 EGCG (Epigallocatechin Gallate)
9 Fisetin
9 Thymoquinone
7 Kaempferol
6 Astragalus
6 Berberine
6 Matrine
6 Metformin
6 Piperine
6 Rosmarinic acid
5 Apigenin (mainly Parsley)
5 Betulinic acid
5 Chrysin
5 Emodin
5 Eugenol
5 Silymarin (Milk Thistle) silibinin
4 Alpha-Lipoic-Acid
4 Baicalein
4 Propolis -bee glue
4 Chlorogenic acid
4 Diindolylmethane
4 Inositol
4 Morin
4 Pterostilbene
4 Shikonin
3 Artemisinin
3 Atorvastatin
3 5-fluorouracil
3 Cyclopamine
3 salinomycin
3 Genistein (soy isoflavone)
3 Ferulic acid
3 Fucoidan
3 Garcinol
3 HydroxyTyrosol
3 Lycopene
3 Magnolol
3 Melatonin
3 Nimbolide
3 Piperlongumine
3 Urolithin
2 Anethole/trans-Anethole
2 Cisplatin
2 Astaxanthin
2 Beta-Caryophyllene
2 brusatol
2 Capsaicin
2 Cannabidiol
2 Celecoxib
2 Centella asiatica / Gotu kola → asiaticoside
2 Crocetin
2 Radiotherapy/Radiation
2 Deguelin
2 Dandelion Root
2 Disulfiram
2 Ellagic acid
2 Sorafenib (brand name Nexavar)
2 Paclitaxel/Taxol
2 Ginkgetin
2 Grapeseed extract
2 phytic acid, Inositol hexakisphosphate
2 Isoliquiritigenin
2 isoflavones
2 isoorientin
2 isoquercitrin
2 Ivermectin
2 Juglone
2 Licorice
2 Lactoferrin/Talactoferrin
2 Naringin
2 Phenethyl isothiocyanate
2 Vitamin C (Ascorbic Acid)
2 Vitamin D3
2 VitK3,menadione
1 1,8-Cineole
1 Anthocyanins
1 Silver-NanoParticles
1 Allicin (mainly Garlic)
1 alpha Linolenic acid
1 DTS(dibenzyl trisulphide) from Anamu
1 Aspirin
1 Baicalin
1 Berbamine
1 Biochanin A
1 Brucea javanica
1 Boron
1 Carnosic acid
1 Caffeic acid
1 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
1 Cucurbitacin
1 Oxaliplatin
1 Dichloroacetate
1 Docosahexaenoic Acid
1 immunotherapy
1 Copper and Cu NanoParticles
1 Ginkgo biloba-EGb 761
1 Eurycomanone
1 Cinnamon
1 Evodiamine
1 Shilajit/Fulvic Acid
1 Gallic acid
1 Ginkgolide B
1 Proanthocyanidins
1 Hydrogen Gas
1 Chemotherapy
1 Hydroxycinnamic-acid
1 Hyperoside
1 Isovitexin
1 methotrexate
1 Lutein
1 mebendazole
1 MCT, metronomic chemo
1 Magnetic Fields
1 Lemon Balm/Melissa officinalis
1 Myricetin
1 Niclosamide (Niclocide)
1 Oleocanthal
1 Plumbagin
1 Psoralidin
1 Sanguinarine
1 α-Santalol/Sandalwood oil
1 Selenium
1 Selenate
1 Gemcitabine (Gemzar)
1 Selenite (Sodium)
1 statins
1 Citric Acid
1 Terpinen-4-ol / Tea Tree Oil
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vitamin K2
1 Vitexin
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:96  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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