Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
3502- Bor,    Plasma boron concentrations in the general population: a cross-sectional analysis of cardio-metabolic and dietary correlates
- Review, NA, NA
*Half-Life↑, *VitD↑, *cardioP↑, *RenoP↓,
3503- Bor,    Chemical disposition of boron in animals and humans
- Review, NA, NA
*Half-Life↑, *other↑,
3504- Bor,    Boron Contents of German Mineral and Medicinal Waters and Their Bioavailability in Drosophila melanogaster and Humans
- Review, NA, NA
other↑, BioAv↑,
3505- Bor,    Mineral requirements for mitochondrial function: A connection to redox balance and cellular differentiation
- Review, NA, NA
*glucose↓, *creat↓, *SOD↑, *MMP↑, *ROS↓,
3506- Bor,    Boron Chemistry for Medical Applications
- Review, NA, NA
radioP↑, selectivity↑,
3507- Bor,    Boron inhibits apoptosis in hyperapoptosis condition: Acts by stabilizing the mitochondrial membrane and inhibiting matrix remodeling
*MMP↑, *Cyt‑c↓, *Apoptosis↓, *Casp3↓, *NO↓, *iNOS↓,
3508- Bor,    The Effect of Boron on the UPR in Prostate Cancer Cells is Biphasic
- in-vitro, Pca, LNCaP - in-vitro, Pca, DU145
ER Stress↑, GRP78/BiP↑, p‑eIF2α↑, UPR↑, eff↓,
3509- Bor,    Boron and Prostate Cancer a Model for Understanding Boron Biology
- NA, Pca, NA
Ca+2↓,
3510- Bor,    Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks
- in-vivo, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *Apoptosis↓, *NRF2↑, *HO-1↑, *MDA↓, *lipid-P↓, *GPx↓, *Catalase↑, *SOD↑, *ALAT↓, *AST↓, *ALP↓,
3511- Bor,    Boron
- Review, NA, NA
*memory↑, *motorD↑, *neuroP↑, Ca+2↓, ATF4↑, NRF2↑, *Inflam↓, *ROS↓,
3512- Bor,    Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake
- in-vitro, Pca, DU145
TumCP↓, eIF2α↑, ATF4↑, ATF6↑, GADD34↑, CHOP↓, GRP78/BiP↑, GRP94↑, Risk↓, *BMD↑, Ca+2↓, *Half-Life↝, IRE1∅, chemoP↑,
3513- Bor,    Boric Acid Activation of eIF2α and Nrf2 Is PERK Dependent: a Mechanism that Explains How Boron Prevents DNA Damage and Enhances Antioxidant Status
- in-vitro, Pca, DU145 - in-vitro, Nor, MEF
NRF2↑, selectivity↑, NQO1↑, GCLC↑, HO-1↑, TumCP↓,
3520- Bor,    Effect of boron element on photoaging in rats
- in-vivo, NA, NA
*hepatoP↑, *BMD↑, *COX2↓, *IL8↓, *NF-kB↓, *IL6↓, *TNF-α↓,
3521- Bor,    A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway
- in-vitro, Obesity, 3T3
*CEBPA↓, *PPARγ↓, *FASN↓, *SREBP1↓, *FABP4↓, *GLUT4↓, *β-catenin/ZEB1↑, *MMP2↓, *FGF↑, *Ca+2?,
3527- Bor,    The potential role of borophene as a radiosensitizer in boron neutron capture therapy (BNCT) and particle therapy (PT)
- NA, Var, NA
RadioS↑,
3525- Bor,    Synthesis of DNA-Boron Cluster Composites and Assembly into Functional Nanoparticles with Dual, Anti-EGFR, and Anti-c-MYC Oncogene Silencing Activity
- in-vitro, PC, PANC1
EGFR↓, cMyc↓,
3524- Bor,    Boric Acid Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice
*Inflam↓, *SOD↑, *MDA↓, *GRP78/BiP↓, *CHOP↓, *NRF2↑, *HO-1↑,
3523- Bor,    Design, Synthesis, and Biological Activity of Boronic Acid-Based Histone Deacetylase Inhibitors
- in-vitro, Var, NA
HDAC↓,
3522- Bor,    The Boron Advantage: The Evolution and Diversification of Boron’s Applications in Medicinal Chemistry
- Review, Var, NA
Hif1a↓, HDAC↓, *CXCR2↑, ROS↑,
3519- Bor,    Boron-Based Inhibitors of the NLRP3 Inflammasome
- Review, NA, NA
NLRP3↓,
3786- Bor,    New and potential boron-containing compounds for treatment of Alzheimer's disease and cancers
- Analysis, AD, NA - Analysis, Var, NA
*AChE↓, TumCP↓,
3785- Bor,    Discovery of boron-containing compounds as Aβ aggregation inhibitors and antioxidants for the treatment of Alzheimer's disease
- Analysis, AD, NA
*Aβ↓, *antiOx↑, *IronCh↑, *PDE4↓,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
697- Bor,    Boron-containing compounds as preventive and chemotherapeutic agents for cancer
- Review, NA, NA
serineP↓, NADHdeh↓, Apoptosis↑,
698- Bor,    Boron deprivation decreases liver S-adenosylmethionine and spermidine and increases plasma homocysteine and cysteine in rats
- in-vitro, NA, NA
SAM-e↑,
699- Bor,    Boric Acid Alleviates Gastric Ulcer by Regulating Oxidative Stress and Inflammation-Related Multiple Signaling Pathways
- in-vivo, NA, NA
*ROS↓, *MDA↓, *TNF-α↓, *IL6↓, *JAK2↓, *STAT3↓, *AMPK↑, *Sema3A/PlexinA1↑,
700- Bor,    Diadenosine phosphates and S-adenosylmethionine: novel boron binding biomolecules detected by capillary electrophoresis
- Analysis, NA, NA
SAM-e↝,
701- Bor,    Dietary boron intake and prostate cancer risk
- Analysis, NA, NA
Risk↓,
702- Bor,  GEN,  SeMet,  Rad,    Evaluation of ecological and in vitro effects of boron on prostate cancer risk (United States)
- Analysis, NA, NA
Risk↓, TumCMig↓, Bcl-2↓,
703- Bor,    Boron intake and prostate cancer risk
- Analysis, NA, NA
Risk∅,
704- Bor,    Inhibition of the enzymatic activity of prostate-specific antigen by boric acid and 3-nitrophenyl boronic acid
- in-vitro, Pca, NA
PSA↓,
705- Bor,    Boric acid inhibits human prostate cancer cell proliferation
- in-vitro, Pca, DU145 - in-vitro, Pca, LNCaP
TumCP↓,
754- Bor,  HRT,    Dietary Boron and Hormone Replacement Therapy as Risk Factors for Lung Cancer in Women
- Analysis, NA, NA
Risk↓,
739- Bor,    Borax regulates iron chaperone- and autophagy-mediated ferroptosis pathway in glioblastoma cells
- in-vitro, GBM, U87MG - in-vitro, Nor, HMC3
TumCG↓, TumCP↓, TumCCA↑, PCBP1↓, GSH↓, GPx4↓, Beclin-1↑, MDA↑, ACSL4↑, Casp3↑, Casp7↑, Ferroptosis↑, *toxicity↓,
740- Bor,    Anti-cancer effect of boron derivatives on small-cell lung cancer
- in-vitro, Lung, DMS114 - in-vitro, Nor, MRC-5
Apoptosis↑, TumCCA↑, P53↑, Casp3↑, *toxicity↓,
741- Bor,    Boron Derivatives Inhibit the Proliferation of Breast Cancer Cells and Affect Tumor-Specific T Cell Activity In Vitro by Distinct Mechanisms
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
MOB1↓, PD-L1↑, p‑YAP/TEAD↝, IFN-γ↓, sFasL↑, Perforin↓, GranA↓, GranB↓, GNLY↓, PD-1↑,
742- Bor,    In Vitro Effects of Boric Acid on Cell Cycle, Apoptosis, and miRNAs in Medullary Thyroid Cancer Cells
- in-vitro, Thyroid, NA
NOXA↑, APAF1↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, Bcl-xL↓, miR-21↓,
743- Bor,    Boric Acid (Boron) Attenuates AOM-Induced Colorectal Cancer in Rats by Augmentation of Apoptotic and Antioxidant Mechanisms
- in-vitro, CRC, NA
BAX↑, Bcl-2↓, GPx↑, SOD↑, Catalase↑, MDA↓, TNF-α↓, IL6↓, IL10↑,
744- Bor,    Borax affects cellular viability by inducing ER stress in hepatocellular carcinoma cells by targeting SLC12A5
- in-vitro, HCC, HepG2 - in-vitro, Nor, HL7702
TumCCA↑, SLC12A5↓, ATF6↑, CHOP↑, GRP78/BiP↑, Casp3↑, ER Stress↝, *toxicity↓, *eff↓,
745- Bor,    Investigation of cytotoxic antiproliferative and antiapoptotic effects of nanosized boron phosphate filled sodium alginate composite on glioblastoma cancer cells
- in-vitro, GBM, U87MG - in-vitro, Nor, L929 - in-vitro, GBM, T98G
TumCD↑, *toxicity↓,
746- Bor,    Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
- Review, NA, NA
eff↑, *toxicity↓, ROS↑, LAT↓, AntiCan↑, AR↓, PSMB5↓, IGF-1↓, PSA↓, TumVol↓, eff↑, Rho↓, Cdc42↓, Ca+2↓, eff↑,
747- Bor,    Growing Evidence for Human Health Benefits of Boron
- Review, NA, NA
TumCG↓, Risk↓,
748- Bor,    A Study on the Anticarcinogenic Effects of Calcium Fructoborate
- in-vitro, BC, MDA-MB-231
p‑ATM↑, p‑P53↑, Casp9↑, PARP↓, VEGF↓, Casp3↑,
749- Bor,    Comparative effects of boric acid and calcium fructoborate on breast cancer cells
P53↓, Bcl-2↓, Casp3↑, Apoptosis↑,
750- Bor,    Calcium fructoborate regulate colon cancer (Caco-2) cytotoxicity through modulation of apoptosis
- in-vitro, CRC, Caco-2
Bcl-2↓, BAX↑, Akt↓, p70S6↓, PTEN↑, TSC2↑,
751- Bor,  5-FU,    Cytotoxic and Apoptotic Effects of the Combination of Borax (Sodium Tetraborate) and 5-Fluorouracil on DLD-1 Human Colorectal Adenocarcinoma Cell Line
- in-vitro, CRC, DLD1
Apoptosis↑,
752- Bor,    The Potential Role of Boron in the Modulation of Gut Microbiota Composition: An In Vivo Pilot Study
GutMicro↑,
753- Bor,    Boron Intake and decreased risk of mortality in kidney transplant recipients
OS↑,
707- Bor,    Cytotoxic and apoptotic effects of boron compounds on leukemia cell line
- in-vitro, AML, HL-60
Apoptosis↑,
755- Bor,    https://aacrjournals.org/cancerres/article/67/9_Supplement/4220/535557/Boric-acid-induces-apoptosis-in-both-prostate-and
- in-vitro, Pca, DU145 - in-vitro, PC, PC3
TumCG↓, Apoptosis↑,

Showing Research Papers: 1501 to 1550 of 5804
Prev Page 31 of 117 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5804

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↑, 1,   Ferroptosis↑, 1,   GCLC↑, 1,   GPx↑, 1,   GPx4↓, 1,   GSH↓, 1,   HO-1↑, 1,   MDA↓, 1,   MDA↑, 1,   NADHdeh↓, 1,   NQO1↑, 1,   NRF2↑, 2,   ROS↑, 2,   SAM-e↑, 1,   SAM-e↝, 1,   SOD↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACSL4↑, 1,   cMyc↓, 1,   LAT↓, 1,   PSMB5↓, 1,  

Cell Death ⓘ

Akt↓, 1,   APAF1↑, 1,   Apoptosis↑, 7,   BAX↑, 3,   Bcl-2↓, 5,   Bcl-xL↓, 1,   Casp3↑, 6,   Casp7↑, 1,   Casp9↑, 2,   Ferroptosis↑, 1,   GADD34↑, 1,   GranA↓, 1,   GranB↓, 1,   NOXA↑, 1,   Perforin↓, 1,   sFasL↑, 1,   TumCD↑, 1,   p‑YAP/TEAD↝, 1,  

Kinase & Signal Transduction ⓘ

p70S6↓, 1,   TSC2↑, 1,  

Transcription & Epigenetics ⓘ

miR-21↓, 1,   other↑, 1,  

Protein Folding & ER Stress ⓘ

ATF6↑, 2,   CHOP↓, 1,   CHOP↑, 1,   eIF2α↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 1,   ER Stress↝, 1,   GRP78/BiP↑, 3,   GRP94↑, 1,   IRE1∅, 1,   UPR↑, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,  

DNA Damage & Repair ⓘ

p‑ATM↑, 1,   P53↓, 1,   P53↑, 1,   p‑P53↑, 1,   PARP↓, 1,  

Cell Cycle & Senescence ⓘ

Cyc↓, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State ⓘ

HDAC↓, 3,   IGF-1↓, 2,   PTEN↑, 1,   TumCG↓, 3,  

Migration ⓘ

Ca+2↓, 4,   Cdc42↓, 1,   MOB1↓, 1,   PCBP1↓, 1,   Rho↓, 1,   serineP↓, 1,   TumCMig↓, 2,   TumCP↓, 5,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   ATF4↑, 2,   EGFR↓, 1,   HIF-1↓, 1,   Hif1a↓, 1,   VEGF↓, 1,  

Barriers & Transport ⓘ

SLC12A5↓, 1,  

Immune & Inflammatory Signaling ⓘ

GNLY↓, 1,   IFN-γ↓, 1,   IL10↑, 1,   IL6↓, 1,   PD-1↑, 1,   PD-L1↑, 1,   PSA↓, 3,   TNF-α↓, 1,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   eff↓, 1,   eff↑, 3,   RadioS↑, 1,   selectivity↑, 2,  

Clinical Biomarkers ⓘ

AR↓, 1,   EGFR↓, 1,   GutMicro↑, 1,   IL6↓, 1,   PD-L1↑, 1,   PSA↓, 3,  

Functional Outcomes ⓘ

AntiCan↑, 2,   chemoP↑, 1,   OS↑, 1,   radioP↑, 1,   Risk↓, 6,   Risk∅, 1,   TumVol↓, 2,  
Total Targets: 108

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   Catalase↑, 2,   GPx↓, 1,   GPx↑, 1,   HO-1↑, 2,   lipid-P↓, 1,   MDA↓, 3,   NRF2↑, 2,   ROS↓, 4,   SAM-e↑, 1,   SOD↑, 4,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↝, 1,   MMP↑, 2,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   AMPK↑, 1,   FABP4↓, 1,   FASN↓, 1,   glucose↓, 1,   NAD↝, 1,   PPARγ↓, 1,   SREBP1↓, 1,  

Cell Death ⓘ

Apoptosis↓, 2,   Casp3↓, 1,   Cyt‑c↓, 1,   iNOS↓, 1,  

Transcription & Epigenetics ⓘ

other↑, 1,  

Protein Folding & ER Stress ⓘ

CHOP↓, 1,   GRP78/BiP↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

CEBPA↓, 1,   FGF↑, 1,   STAT3↓, 1,  

Migration ⓘ

Ca+2?, 1,   Ca+2↝, 1,   MMP2↓, 1,   Sema3A/PlexinA1↑, 1,   serineP↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Barriers & Transport ⓘ

GLUT4↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   CXCR2↑, 1,   IL6↓, 2,   IL8↓, 1,   Inflam↓, 3,   JAK2↓, 1,   NF-kB↓, 1,   TNF-α↓, 3,   VitD↑, 2,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,  

Hormonal & Nuclear Receptors ⓘ

testos↑, 1,  

Drug Metabolism & Resistance ⓘ

Dose↑, 1,   Dose↝, 1,   eff↓, 1,   eff↑, 1,   Half-Life↑, 2,   Half-Life↝, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   BMD↑, 3,   BMPs↑, 1,   Calcium↑, 1,   creat↓, 1,   hs-CRP↓, 1,   IL6↓, 2,   Mag↑, 1,   VitD↑, 2,  

Functional Outcomes ⓘ

cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   ChemoSideEff↓, 1,   cognitive↑, 1,   hepatoP↑, 1,   memory↑, 2,   motorD↑, 1,   neuroP↑, 2,   PDE4↓, 1,   RenoP↓, 1,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 5,  
Total Targets: 84

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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