Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
5715- BF,    Bufalin for an innovative therapeutic approach against cancer
- Review, Var, NA
selectivity↑, TumCP↓, TumCCA↓, TumCD↑, Apoptosis↑, TumAuto↑, TumMeta↓, TumCMig↓, TumCI↓, angioG↓, CSCs↓,
5597- Bical,    Bicalutamide: clinical pharmacokinetics and metabolism
- Review, Pca, NA
Dose↝, BioAv↑, Half-Life↑, CYP3A4↓, PSA↓,
2502- Bical,    Complete Response of Metastatic Androgen Receptor–Positive Breast Cancer to Bicalutamide: Case Report and Review of the Literature
- Case Report, BC, NA
Dose↝, Remission↑,
5621- Bif,  immuno,    Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
TumCG↓, GutMicro↑,
5622- Bif,    Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice
- in-vivo, Var, NA
eff↑, Imm↑, IFN-γ↑,
5623- Bif,    Bifidobacterium breve predicts the efficacy of anti-PD-1 immunotherapy combined with chemotherapy in Chinese NSCLC patients
- Study, NSCLC, NA
GutMicro↑, OS↑, eff↑,
5625- Bif,  immuno,    The gut microbiome and cancer response to immune checkpoint inhibitors
- Review, Var, NA
eff↑, eff↓,
5626- Bif,    Bifidobacterium in anticancer immunochemotherapy: friend or foe?
- Review, Var, NA
*Inflam↓, *Treg lymp↑, *IL10?, Imm↑, eff↑,
5627- Bif,    Efficacy and Safety of Probiotics as Adjunctive Therapy in Cancer Treatment: A Comprehensive Systematic Review and Meta-Analysis
- Review, Var, NA
Diar↓,
5628- Bif,  immuno,    Bifidobacterium modulation of tumor immunotherapy and its mechanism
- Review, Var, NA
Imm↑, Risk↓, GutMicro↑, AntiTum↑, OS↑, selectivity↑, eff↑,
5629- Bif,  ProBio,    Gut microbiota shapes cancer immunotherapy responses
- Review, Var, NA
eff↑, DCells↑, CD8+↑, eff↑, AntiTum↑, other↑, selectivity↑, GutMicro↑,
1250- Bif,    Oral administration of Bifidobacterium breve promotes antitumor efficacy via dendritic cells-derived interleukin 12
- in-vitro, SCC, NA
TumCG↓, Apoptosis↑, CCL20↑, IL12↑,
5688- BJ,    Brucea Javanica Oil Emulsion Injection inhibits proliferation of pancreatic cancer via regulating apoptosis-related genes
- vitro+vivo, PC, MIA PaCa-2
TumCG↓, TumCI↓, TumCCA↑, Apoptosis↑, BAX↑, cl‑Casp3↑, Bcl-2↓, MMP2↓, BACE↓, TOP2↓,
5686- BJ,  BRU,    A review of Brucea javanica: metabolites, pharmacology and clinical application
- Review, Var, NA
AntiTum↑, other↝, ChemoSen↑, QoL↑, chemoP↑, *Inflam↓, NF-kB↓, TumCP↓, TumCI↓, TumMeta↓, Hif1a↓, NRF2↓, STAT3↓, COX2↓, Casp3↑, Casp9↑, ROS↑, EGFR↓, NRF2↑,
5687- BJ,    Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways
- vitro+vivo, AML, U937
Apoptosis↑, Casp8↑, TumCCA↑, cl‑PARP↑, eff↝, TumCG↓, necrosis↑, Fas↑, TumCCA↑, selectivity↑,
5689- BJ,    Brucea javanica oil inhibited the proliferation, migration, and invasion of oral squamous carcinoma by regulated the MTFR2 pathway
- vitro+vivo, Oral, CAL27
TumCP↓, TumCMig↓, TumCI↓, SOD2↓, H2O2↓, OXPHOS↑, Glycolysis↓, ROS↑, RadioS↑, Hif1a↓, TumCG↓,
5690- BJ,  BRU,    Brusatol: A potential sensitizing agent for cancer therapy from Brucea javanica
- Review, Var, NA
NRF2↓, TumCG↓, ChemoSen↑, ROS↑, NF-kB↓, Akt↓, mTOR↓, TumCCA↑, Apoptosis↑, PARP↑, Casp↑, P53↓, Bcl-2↓, PI3K↓, JAK2↓, EMT↓, p27↑, ROCK1↓, MMP2↓, MMP9↓, NRF2↓, AntiTum↑, HO-1↓, NQO1↓, VEGF↓, MRP1/ABCC1↓, RadioS↑, PhotoS↑, toxicity↝,
5692- BJ,    Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells
- vitro+vivo, AML, NA
Apoptosis↑, Akt↓, P53↑, FOXO1↑, GSK‐3β↑, TumVol↓, QoL↑, BBB↑, OS↑, Dose↝, MMP↓, ROS↑, XIAP↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, TumCCA↑,
5483- BM,    The Role of Bacopa monnieri in Alzheimer’s Disease: Mechanisms and Potential Clinical Use—A Review
- Review, AD, NA
*cognitive↑, *neuroP↑, *PI3K↑, *Akt↑, *GSK‐3β↓, *tau↓, *ROS↓, *MMP3↓, *Casp1↓, *Casp3↓, *NF-kB↓, *TNF-α↓, *IL6↓,
5478- BM,    A systematic review of the safety and efficacy on cognitive function of herbal and nutritional medicines in older adults with and without subjective cognitive impairment
- Review, AD, NA
*cognitive∅,
5479- BM,    Importance of high-quality evidence regarding the use of Bacopa monnieri in dementia
- Review, AD, NA
other↝,
5480- BM,    Inhibition of Human Cytochrome P450 Enzymes by Bacopa monnieri Standardized Extract and Constituents
- Human, Nor, NA
P450↓, CYP3A4↓, CYP2C9↓,
5481- BM,    Therapeutic potential of Bacopa monnieri extracts against hepatocellular carcinoma through in-vitro and computational studies
- in-vitro, HCC, HepG2
tumCV↓, Apoptosis↑, TumCP↓, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, lipid-P↓,
5482- BM,    Bacopa monnieri protects SH-SY5Y cells against tert-Butyl hydroperoxide-induced cell death via the ERK and PI3K pathways
- in-vitro, Nor, NA
*neuroP↑, *ERK↑, *Akt↑, *MAPK↑, *PI3K↑, *Inflam↓, antiOx↑,
5484- BM,    The Neurocognitive Effects of Bacopa monnieri and Cognitive Training on Markers of Brain Microstructure in Healthy Older Adults
- in-vivo, AD, NA
*memory↓, *other?,
5485- BM,    Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis
- Review, AD, NA
*memory↑,
5486- BM,    Bacopaside I, acting as an aquaporin 1 inhibitor, ameliorates rheumatoid arthritis via suppressing aquaporin 1-mediated autophagy
- in-vivo, Arthritis, NA
*AQPs↓, TumCP↓, Apoptosis↑,
5473- BM,    Bacopa monnieri: Preclinical and Clinical Evidence of Neuroactive Effects, Safety of Use and the Search for Improved Bioavailability
- in-vivo, AD, NA - in-vivo, Park, NA
*neuroP↑, *toxicity∅, *AChE↓, *ROS↓, *antiOx↑, *lipid-P↓, *cognitive↑, *memory↑, *Dose↝, *BioAv↓, *TumCCA↑, *BBB↝,
5477- BM,    The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis.
- in-vitro, Var, NA
AQPs↓, tumCV↓, Apoptosis↑, TumCMig↓,
5474- BM,    Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation
*memory↑, *neuroP↑, *cognitive↑, *hepatoP↑, *antiOx↑, *AntiDiabetic↑, *fatigue↓, *GSK‐3β↓, *PI3K↑, *Akt↑, *tau↓, *ROS↓, *Inflam↓,
5475- BM,    The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis
- in-vitro, Colon, HT29 - in-vitro, Colon, SW48 - in-vitro, Colon, SW-620 - in-vitro, CRC, HCT116
AQPs↓, TumCG↓, TumCCA↓, Apoptosis↑, eff↝,
5476- BM,    In Vitro Synergistic Inhibition of HT-29 Proliferation and 2H-11 and HUVEC Tubulogenesis by Bacopaside I and II Is Associated with Ca2+ Flux and Loss of Plasma Membrane Integrity
- vitro+vivo, CRC, HT29
TumCD↑, TumCMig↓, Ca+2↑,
3694- BM,    Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials
- Review, AD, NA
*cognitive∅, *other↑,
3693- BM,    Bacopa monnieri prevents colchicine-induced dementia by anti-inflammatory action
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *BACE↓, *Inflam↓, *ROS↓, *antiOx↑,
3698- BM,    Bacopa monniera prevents from aluminium neurotoxicity in the cerebral cortex of rat brain
- in-vivo, AD, NA
*lipid-P↓, *ROS↓, *neuroP↑,
3695- BM,    Bacopa monnieri (L.) wettst. Extract protects against glutamate toxicity and increases the longevity of Caenorhabditis elegans
- in-vitro, AD, HT22
*OS↑, *mt-ROS↓, *ROS↓, *neuroP↑, *ER Stress↓,
3696- BM,    Discovery of Molecular Networks of Neuroprotection Conferred by Brahmi Extract in Aβ42-Induced Toxicity Model of Drosophila melanogaster Using a Quantitative Proteomic Approach
- in-vivo, NA, NA
*neuroP↑, *memory↑,
3697- BM,    Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies
- Review, AD, NA
*ROS↓, *cognitive↑, *memory↑, *BBB↑, *P-gp↓, *CYP3A2↓,
3692- BM,    Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *Aβ↓, *cognitive↑,
3691- BM,    Effects of a Standardized Bacopa monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly: A Randomized, Double-Blind, Placebo-Controlled Trial
- Study, Nor, NA
*cognitive↑, *memory↑, *BP∅,
3690- BM,    Neurocognitive Effect of Nootropic Drug Brahmi (Bacopa monnieri) in Alzheimer's Disease
- Review, AD, NA
*ROS↓, *5LO↓, *lipid-P↓, *GPx↑, *IronCh↑, *neuroP↑, *AChE↓, *memory↑, *toxicity↓, *SOD↑, *Catalase↑, *cognitive↑, *ChAT↑, *Ach↑, *BP↓,
4277- BM,    Reversion of BDNF, Akt and CREB in Hippocampus of Chronic Unpredictable Stress Induced Rats: Effects of Phytochemical, Bacopa Monnieri
- in-vivo, NA, NA
*BDNF↑, *p‑CREB↑,
5684- BML,    Bromelain mediates apoptosis in HeLa cells via ROS-independent pathway
- in-vitro, Cerv, HeLa
ROS↑, Apoptosis↑, P53↑, TumCMig↓,
5680- BML,    Anticancer properties of bromelain: State-of-the-art and recent trends
- Review, Var, NA
*Inflam↓, *Bacteria↓, *Pain↓, *Diar↓, *Wound Healing↑, ERK↓, JNK↓, XIAP↓, HSP27↓, β-catenin/ZEB1↓, HO-1↓, lipid-P↓, ACSL4↑, ROS↑, SOD↑, Catalase↓, GSH↓, MDA↓, Casp3↓, Casp9↑, DNAdam↑, Apoptosis↑, NF-kB↓, P53↑, MAPK↓, APAF1↑, Cyt‑c↓, CD44↓, Imm↑, ATG5↑, LC3I↑, Beclin-1↑, IL2↓, IL4↓, IFN-γ↓, COX2↓, iNOS↓, ChemoSen↑, RadioS↑, Dose↝, other↓,
5679- BML,    Bromelain proteinases modulate the cd44 expression on human molt-4/8 leukemia and sk-mel-28 melanoma-cells in-vitro
- in-vitro, Melanoma, SK-MEL-28
CD44↓,
5678- BML,    Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy
- in-vivo, CRC, NA
AntiCan↑, TumCG↓, ROS↑, Apoptosis↑, Endoglin↑, Casp3↑, Casp8↑, Casp9↑, ATG5↑, Beclin-1↑, p62↑, PARP↑,
5677- BML,    Bromelain inhibits nuclear factor kappa-B translocation, driving human epidermoid carcinoma A431 and melanoma A375 cells through G(2)/M arrest to apoptosis
- in-vitro, Melanoma, A431 - in-vitro, Melanoma, A375
TumCP↓, Inflam↓, Akt↓, NF-kB↓, COX2↓, GSH↓, ROS↑, MMP↓, TumCCA↑, Apoptosis↑, ChemoSen↑,
5676- BML,    Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake
- in-vivo, NA, NA
Half-Life↝, Dose↝, Dose↝,
5681- BML,    Supplementation Containing Bromelain on the Side Effects of Oncological Treatment: Systematic Review
- Review, Var, NA
Inflam↓, chemoP↑,
5682- BML,    A novel treatment of bromelain and acetylcysteine (BromAc) in patients with peritoneal mucinous tumours: A phase I first in man study
- Human, Var, NA
Dose↝, toxicity↝, eff↑,

Showing Research Papers: 1501 to 1550 of 7372
Prev Page 31 of 148 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7372

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↓, 1,   GSH↓, 2,   H2O2↓, 1,   HO-1↓, 2,   lipid-P↓, 2,   MDA↓, 1,   NQO1↓, 1,   NRF2↓, 3,   NRF2↑, 1,   OXPHOS↑, 1,   ROS↑, 8,   SOD↑, 1,   SOD2↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 2,   XIAP↓, 1,   XIAP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↑, 1,   CYP3A4↓, 2,   Glycolysis↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   APAF1↑, 1,   Apoptosis↑, 14,   BAX↑, 1,   Bcl-2↓, 2,   Casp↑, 1,   Casp3↓, 1,   Casp3↑, 3,   cl‑Casp3↑, 1,   Casp8↑, 3,   Casp9↑, 4,   Cyt‑c↓, 1,   Fas↑, 1,   iNOS↓, 1,   JNK↓, 1,   MAPK↓, 1,   necrosis↑, 1,   p27↑, 1,   TumCD↑, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↑, 1,   other↝, 2,   PhotoS↑, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP27↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   Beclin-1↑, 2,   LC3I↑, 1,   p62↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   P53↓, 1,   P53↑, 3,   PARP↑, 2,   cl‑PARP↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↓, 2,   TumCCA↑, 6,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD44↓, 2,   CSCs↓, 1,   EMT↓, 1,   ERK↓, 1,   FOXO1↑, 1,   GSK‐3β↑, 1,   mTOR↓, 1,   PI3K↓, 1,   STAT3↓, 1,   TOP2↓, 1,   TumCG↓, 8,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   MMP2↓, 3,   MMP9↓, 2,   ROCK1↓, 1,   TumCI↓, 5,   TumCMig↓, 6,   TumCP↓, 6,   TumMeta↓, 2,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   EGFR↓, 1,   Endoglin↑, 1,   Hif1a↓, 2,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 2,   BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCL20↑, 1,   COX2↓, 3,   DCells↑, 1,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL12↑, 1,   IL2↓, 1,   IL4↓, 1,   Imm↑, 4,   Inflam↓, 2,   JAK2↓, 1,   NF-kB↓, 4,   PSA↓, 1,  

Protein Aggregation(tgid=19) ⓘ

BACE↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   ChemoSen↑, 4,   CYP2C9↓, 1,   Dose↝, 7,   eff↓, 1,   eff↑, 8,   eff↝, 2,   Half-Life↑, 1,   Half-Life↝, 1,   MRP1/ABCC1↓, 1,   P450↓, 1,   RadioS↑, 3,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   GutMicro↑, 4,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 4,   chemoP↑, 2,   OS↑, 3,   QoL↑, 2,   Remission↑, 1,   Risk↓, 1,   toxicity↝, 2,   TumVol↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 1,   Diar↓, 1,  
Total Targets: 125

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   Catalase↑, 1,   GPx↑, 1,   lipid-P↓, 3,   ROS↓, 9,   mt-ROS↓, 1,   SOD↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

p‑CREB↑, 1,   CYP3A2↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 3,   Casp1↓, 1,   Casp3↓, 1,   MAPK↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   other?, 1,   other↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   GSK‐3β↓, 2,   PI3K↑, 3,  

Migration(tgid=13) ⓘ

5LO↓, 1,   MMP3↓, 1,   Treg lymp↑, 1,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   BBB↑, 1,   BBB↝, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL10?, 1,   IL6↓, 1,   Inflam↓, 7,   NF-kB↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 2,   BDNF↑, 1,   ChAT↑, 1,   tau↓, 2,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,   BACE↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   Dose↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BP↓, 1,   BP∅, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiDiabetic↑, 1,   cognitive↑, 8,   cognitive∅, 2,   fatigue↓, 1,   hepatoP↑, 1,   memory↓, 1,   memory↑, 7,   neuroP↑, 9,   OS↑, 1,   Pain↓, 1,   toxicity↓, 1,   toxicity∅, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   Diar↓, 1,  
Total Targets: 60

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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