Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
756- Bor,    Evaluation of Boric Acid Treatment on microRNA‐127‐5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells
- in-vitro, BC, MCF-7
COL1A1↓, Vim↓, miR-127-5p↑, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑,
757- Bor,    Phenylboronic acid is a more potent inhibitor than boric acid of key signaling networks involved in cancer cell migration
- in-vitro, Pca, DU145 - in-vitro, Nor, RWPE-1
Rho↓, Rac1↓, Cdc42↓, *eff↑,
758- Bor,    Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
- Human, NA, NA
*hs-CRP↓, *TNF-α↓, *SHBG↓, *DHT↑, *cortisol↑, *VitD↑, *BioAv↑, *Inflam↓,
759- Bor,    The nutritional and metabolic effects of boron in humans and animals
- in-vivo, NA, NA
DHT↑, VitD↑, HDL↓,
760- Bor,    Therapeutic Efficacy of Boric Acid Treatment on Brain Tissue and Cognitive Functions in Rats with Experimental Alzheimer’s Disease
- in-vivo, AD, NA
*memory↑, *ROS↓, *GSH↑, *Aβ↓, *Inflam↓, *MMP↑, *lipid-P↓, *Ca+2↓, *cognitive↑, *TOS↓,
761- Bor,    Prevalence of Prostate Cancer in High Boron-Exposed Population: A Community-Based Study
- Study, BPH, NA
other↓,
762- Bor,    Mechanism of boric acid cytotoxicity in breast cancer cell lines
- in-vitro, BC, MCF-7 - in-vitro, BC, ZR-75-1
TumCG↓,
763- Bor,    Investigation of The Apoptotic and Antiproliferative Effects of Boron on CCL-233 Human Colon Cancer Cells
- in-vitro, Colon, CCl233
TumCP↓, PARP↓, VEGF↓,
764- Bor,    Effect of Tumor Microenvironment on Selective Uptake of Boric Acid in HepG2 Human Hepatoma Cells
- in-vitro, Liver, HepG2
BioAv↑,
765- Bor,    High concentrations of boric acid induce autophagy in cancer cell lines
p62↓, LC3II↑, TumAuto↑,
766- Bor,    In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration
- in-vitro, Liver, HepG2
TumCCA↑, DNAdam↑, Apoptosis↑,
767- Bor,    Boric acid induces cytoplasmic stress granule formation, eIF2α phosphorylation, and ATF4 in prostate DU-145 cells
- in-vitro, Pca, DU145
ER Stress↑, eIF2α↑, GRP78/BiP↑, ATF4↑,
768- Bor,    In vitro and in vivo antitumour effects of phenylboronic acid against mouse mammary adenocarcinoma 4T1 and squamous carcinoma SCCVII cells
- in-vitro, BC, 4T1
TumCP↓,
706- Bor,    Boron supplementation inhibits the growth and local expression of IGF-1 in human prostate adenocarcinoma (LNCaP) tumors in nude mice
- in-vivo, Pca, LNCaP
TumVol↓, IGF-1↓, PSA↓,
737- Bor,    Boric Acid Activation of eIF2α and Nrf2 Is PERK Dependent: a Mechanism that Explains How Boron Prevents DNA Damage and Enhances Antioxidant Statu
- in-vitro, Pca, DU145
Risk↓, p‑eIF2α↑, ATF4↑, GADD34↑,
738- Bor,    Borax induces ferroptosis of glioblastoma by targeting HSPA5/NRF2/GPx4/GSH pathways
- in-vitro, GBM, U251 - in-vitro, GBM, A172 - in-vitro, Nor, SVGp12
TumCP↓, GPx4↓, GSH↓, HSP70/HSPA5↓, NRF2↓, MDA↑, Casp3↑, Casp7↑, Ferroptosis↑, selectivity↑,
708- Bor,    Boron containing compounds as protease inhibitors
PSA↓,
709- Bor,    Cellular changes in boric acid-treated DU-145 prostate cancer cells
- in-vitro, Pca, DU145
Cyc↓, MAPK↓, TumCMig↓, LAMP2↓, p‑ERK⇅, TumCM/A↑,
710- Bor,    Boric acid inhibits stored Ca2+ release in DU-145 prostate cancer cells
- in-vitro, Pca, DU145
NAD↓, TumCP↓, CD38↑, Ca+2↓,
711- Bor,    Receptor Activated Ca2+ Release Is Inhibited by Boric Acid in Prostate Cancer Cells
- in-vitro, Pca, DU145
Ca+2↓,
712- Bor,    Boron concentrations in selected foods from borate-producing regions in Turkey
- Analysis, NA, NA
Risk↓,
713- Bor,    Effects of dietary boron on cervical cytopathology and on micronucleus frequency in exfoliated buccal cells
- Analysis, NA, NA
Risk↓,
714- Bor,    Dietary Boron and Hormone Replacement Therapy as Risk Factors for Lung Cancer in Women
- Analysis, NA, NA
Risk↓,
715- Bor,    Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1alpha inhibitors
- in-vitro, Pca, HeLa
Hif1a↓,
716- Bor,    Sugar-borate esters--potential chemical agents in prostate cancer chemoprevention
TumCG↓, Apoptosis↑,
717- Bor,  PacT,    Boric acid as a protector against paclitaxel genotoxicity
- in-vitro, NA, NA
ChemoSideEff↓,
718- Bor,    Boric Acid Exhibits Anticancer Properties in Human Endometrial Cancer Ishikawa Cells
- in-vitro, NA, NA
OSI↑, TNF-α↓, IL1↓, Casp3↑, Apoptosis↑, TOS↑,
719- Bor,    Boric Acid Affects Cell Proliferation, Apoptosis, and Oxidative Stress in ALL Cells
- in-vitro, Var, NA
Apoptosis↑, miR-21↓, TOS↓,
720- Bor,    High Concentrations of Boric Acid Trigger Concentration-Dependent Oxidative Stress, Apoptotic Pathways and Morphological Alterations in DU-145 Human Prostate Cancer Cell Line
- in-vitro, Pca, DU145
ROS↑, TumCG↓, Apoptosis↑,
721- Bor,    Polymers Based on Phenyl Boric Acid in Tumor-Targeted Therapy
- Analysis, NA, NA
SA↓,
723- Bor,    Boric acid suppresses cell proliferation by TNF signaling pathway mediated apoptosis in SW-480 human colon cancer line
- in-vitro, Colon, SW480
Apoptosis↑, TNF-α↝,
722- Bor,    Boric acid as a promising agent in the treatment of ovarian cancer: Molecular mechanisms
- in-vitro, Ovarian, MDAH-2774
TumCP↓, TumCI↓, TumCMig↓, Apoptosis↑, ROS↑, miR-21↓, miR-130a↓, Casp8∅, Casp10∅, cycD1/CCND1∅, CDK6∅, CDK4∅, FADD∅, DR4∅, DR5∅,
736- Bor,    Evaluation of Boric Acid Treatment on microRNA-127-5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells
- in-vitro, BC, MCF-7
miR-126↑, COL1A1↓, Vim↓, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑, miR-127-5p↑,
735- Bor,    Boric Acid Alters the Expression of DNA Double Break Repair Genes in MCF-7-Derived Breast Cancer Stem Cells
- in-vitro, BC, NA
BRCA1↑, BRCA2↑, ATM↓,
734- Bor,    Boric Acid Affects the Expression of DNA Double-Strand Break Repair Factors in A549 Cells and A549 Cancer Stem Cells: An In Vitro Study
- in-vitro, Lung, A549
ATM↓, Casp3↑, E-cadherin↑,
733- Bor,    The analysis of boric acid effect on epithelial-mesenchymal transition of CD133 + CD117 + lung cancer stem cells
- in-vitro, Lung, NA
Snail↑, ITGB1↑, ITGA5↑, COL1A1↓, LAMA5↑, MMP3↓, Vim↓, E-cadherin↑, EMT↓, Zeb1↑,
732- Bor,    Boron's neurophysiological effects and tumoricidal activity on glioblastoma cells with implications for clinical treatment
eff↑, IGF-1↝, Glycolysis↝,
731- Bor,    Protective Effect of Boric Acid Against Ochratoxin A-Induced Toxic Effects in Human Embryonal Kidney Cells (HEK293): A Study on Cytotoxic, Genotoxic, Oxidative, and Apoptotic Effects
- in-vitro, Nor, HEK293
*ROS↓,
729- Bor,    Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies
- in-vitro, GBM, U87MG - in-vivo, Nor, HaCaT
TOS↑, TumCG↓, MDA↑, SOD↑, Catalase↑, TAC↓, GSH↓, BRAF↑, MAPK↓, PTEN↓, Raf↓, *toxicity↓,
728- Bor,    Boric Acid and Borax Protect Human Lymphocytes from Oxidative Stress and Genotoxicity Induced by 3-Monochloropropane-1,2-diol
other↓,
727- Bor,  RSL3,  erastin,    Enhancement of ferroptosis by boric acid and its potential use as chemosensitizer in anticancer chemotherapy
- in-vitro, Liver, HepG2
ROS↑, GSH↓, TBARS↑, Ferroptosis↑, ChemoSen↑,
726- Bor,    Redox Mechanisms Underlying the Cytostatic Effects of Boric Acid on Cancer Cells—An Issue Still Open
- Review, NA, NA
NAD↝, SAM-e↝, PSA↓, IGF-1↓, Cyc↓, P21↓, p‑MEK↓, p‑ERK↓, ROS↑, SOD↓, Catalase↓, MDA↑, GSH↓, IL1↓, IL6↓, TNF-α↓, BRAF↝, MAPK↝, PTEN↝, PI3K/Akt↝, eIF2α↑, ATF4↑, ATF6↑, NRF2↑, BAX↑, BID↑, Casp3↑, Casp9↑, Bcl-2↓, Bcl-xL↓,
725- Bor,    Boric acid exert anti-cancer effect in poorly differentiated hepatocellular carcinoma cells via inhibition of AKT signaling pathway
- in-vitro, HCC, NA
tumCV↓, Apoptosis↑, TumAuto↑, p‑Akt↓,
724- Bor,    Does Boric Acid Inhibit Cell Proliferation on MCF-7 and MDA-MB-231 Cells in Monolayer and Spheroid Cultures by Using Apoptosis Pathways?
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF-7
Apoptosis↑, Casp3↝, Casp8↝, Casp9↝,
730- Bor,  Cisplatin,    The Effect of Boric Acid and Borax on Oxidative Stress, Inflammation, ER Stress and Apoptosis in Cisplatin Toxication and Nephrotoxicity Developing as a Result of Toxication
- in-vivo, NA, NA
*ROS↓, *Inflam↓, RenoP↑,
4272- Bor,    Neuroprotective properties of borax against aluminum hydroxide-induced neurotoxicity: Possible role of Nrf-2/BDNF/AChE pathways in fish brain
*NRF2↑, *ROS↓, *antiOx↑, *lipid-P↑, *Inflam↓, *DNAdam↓, *BDNF↑, *neuroP↑, *GSH↑,
4271- Bor,    Effects of Boron on Learning and Behavioral Disorders in Rat Autism Model Induced by Intracerebroventricular Propionic Acid
- in-vivo, NA, NA
*BDNF↝,
4620- Bor,  BTZ,    Boron Compounds in the Breast Cancer Cells Chemoprevention and Chemotherapy
- Review, Var, NA - Review, Arthritis, NA - Review, Pca, NA
Risk↓, *memory↑, *Dose↑, Risk↓, other↝, *testos↑, other↝, Risk↓, TumCP↓, Apoptosis↑, eff↑,
4619- Bor,    Using Boron Supplementation in Cancer Prevention and Treatment: A Review Article
- Review, Var, NA
Dose↝, Risk↓, *antiOx↓, *Inflam↓, ChemoSen↑, AntiCan↑, *PCNA↓, *ROS↓, other↝,
4621- Bor,    Boron
- Review, BPH, NA
*other↝, Risk↑, *Dose↑,

Showing Research Papers: 1551 to 1600 of 5806
Prev Page 32 of 117 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5806

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↓, 1,   Catalase↑, 1,   Ferroptosis↑, 2,   GPx4↓, 1,   GSH↓, 4,   HDL↓, 1,   MDA↑, 3,   NRF2↓, 1,   NRF2↑, 1,   OSI↑, 1,   ROS↑, 4,   SAM-e↝, 1,   SOD↓, 1,   SOD↑, 1,   TAC↓, 1,   TBARS↑, 1,   TOS↓, 1,   TOS↑, 2,  

Mitochondria & Bioenergetics ⓘ

p‑MEK↓, 1,   Raf↓, 1,  

Core Metabolism/Glycolysis ⓘ

Glycolysis↝, 1,   NAD↓, 1,   NAD↝, 1,   PI3K/Akt↝, 1,   TumCM/A↑, 1,  

Cell Death ⓘ

p‑Akt↓, 1,   Apoptosis↑, 10,   BAX↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   BID↑, 1,   Casp10∅, 1,   Casp3↑, 4,   Casp3↝, 1,   Casp7↑, 1,   Casp8↝, 1,   Casp8∅, 1,   Casp9↑, 1,   Casp9↝, 1,   DR4∅, 1,   DR5∅, 1,   FADD∅, 1,   Ferroptosis↑, 2,   GADD34↑, 1,   MAPK↓, 2,   MAPK↝, 1,   miR-127-5p↑, 2,  

Transcription & Epigenetics ⓘ

miR-21↓, 2,   other↓, 2,   other↝, 3,   tumCV↓, 1,  

Protein Folding & ER Stress ⓘ

ATF6↑, 1,   eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↓, 1,  

Autophagy & Lysosomes ⓘ

LAMP2↓, 1,   LC3II↑, 1,   p62↓, 1,   TumAuto↑, 2,  

DNA Damage & Repair ⓘ

ATM↓, 2,   BRCA1↑, 1,   BRCA2↑, 1,   DNAdam↑, 1,   PARP↓, 1,  

Cell Cycle & Senescence ⓘ

CDK4∅, 1,   Cyc↓, 2,   cycD1/CCND1∅, 1,   P21↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

BRAF↑, 1,   BRAF↝, 1,   EMT↓, 1,   p‑ERK↓, 1,   p‑ERK⇅, 1,   IGF-1↓, 2,   IGF-1↝, 1,   PTEN↓, 1,   PTEN↝, 1,   TumCG↓, 4,  

Migration ⓘ

Ca+2↓, 2,   CD38↑, 1,   Cdc42↓, 1,   CDH1↑, 2,   COL1A1↓, 3,   E-cadherin↑, 2,   ITGA5↑, 3,   ITGB1↑, 3,   LAMA5↑, 3,   miR-130a↓, 1,   MMP3↓, 1,   Rac1↓, 1,   Rho↓, 1,   SA↓, 1,   Snail↑, 3,   TumCI↓, 1,   TumCMig↓, 2,   TumCP↓, 6,   Vim↓, 3,   Zeb1↑, 3,  

Angiogenesis & Vasculature ⓘ

ATF4↑, 3,   Hif1a↓, 1,   miR-126↑, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL1↓, 2,   IL6↓, 1,   PSA↓, 3,   TNF-α↓, 2,   TNF-α↝, 1,   VitD↑, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6∅, 1,   DHT↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   ChemoSen↑, 2,   Dose↝, 1,   eff↑, 2,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

BRAF↑, 1,   BRAF↝, 1,   BRCA1↑, 1,   IL6↓, 1,   PSA↓, 3,   VitD↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   ChemoSideEff↓, 1,   RenoP↑, 1,   Risk↓, 8,   Risk↑, 1,   TumVol↓, 1,  
Total Targets: 130

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 1,   GSH↑, 2,   lipid-P↓, 1,   lipid-P↑, 1,   NRF2↑, 1,   ROS↓, 5,   TOS↓, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↑, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,   PCNA↓, 1,  

Migration ⓘ

Ca+2↓, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 5,   TNF-α↓, 1,   VitD↑, 1,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,   BDNF↝, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,  

Hormonal & Nuclear Receptors ⓘ

cortisol↑, 1,   DHT↑, 1,   SHBG↓, 1,   testos↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   Dose↑, 2,   eff↑, 1,  

Clinical Biomarkers ⓘ

hs-CRP↓, 1,   VitD↑, 1,  

Functional Outcomes ⓘ

cognitive↑, 1,   memory↑, 2,   neuroP↑, 1,   toxicity↓, 1,  
Total Targets: 32

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page