Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
742- Bor,    In Vitro Effects of Boric Acid on Cell Cycle, Apoptosis, and miRNAs in Medullary Thyroid Cancer Cells
- in-vitro, Thyroid, NA
NOXA↑, APAF1↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, Bcl-xL↓, miR-21↓,
743- Bor,    Boric Acid (Boron) Attenuates AOM-Induced Colorectal Cancer in Rats by Augmentation of Apoptotic and Antioxidant Mechanisms
- in-vitro, CRC, NA
BAX↑, Bcl-2↓, GPx↑, SOD↑, Catalase↑, MDA↓, TNF-α↓, IL6↓, IL10↑,
744- Bor,    Borax affects cellular viability by inducing ER stress in hepatocellular carcinoma cells by targeting SLC12A5
- in-vitro, HCC, HepG2 - in-vitro, Nor, HL7702
TumCCA↑, SLC12A5↓, ATF6↑, CHOP/DDIT3↑, GRP78/BiP↑, Casp3↑, ER Stress↝, *toxicity↓, *eff↓,
745- Bor,    Investigation of cytotoxic antiproliferative and antiapoptotic effects of nanosized boron phosphate filled sodium alginate composite on glioblastoma cancer cells
- in-vitro, GBM, U87MG - in-vitro, Nor, L929 - in-vitro, GBM, T98G
TumCD↑, *toxicity↓,
746- Bor,    Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
- Review, NA, NA
eff↑, *toxicity↓, ROS↑, LAT↓, AntiCan↑, AR↓, PSMB5↓, IGF-1↓, PSA↓, TumVol↓, eff↑, Rho↓, Cdc42↓, Ca+2↓, eff↑,
747- Bor,    Growing Evidence for Human Health Benefits of Boron
- Review, NA, NA
TumCG↓, Risk↓,
748- Bor,    A Study on the Anticarcinogenic Effects of Calcium Fructoborate
- in-vitro, BC, MDA-MB-231
p‑ATM↑, p‑P53↑, Casp9↑, PARP↓, VEGF↓, Casp3↑,
749- Bor,    Comparative effects of boric acid and calcium fructoborate on breast cancer cells
P53↓, Bcl-2↓, Casp3↑, Apoptosis↑,
750- Bor,    Calcium fructoborate regulate colon cancer (Caco-2) cytotoxicity through modulation of apoptosis
- in-vitro, CRC, Caco-2
Bcl-2↓, BAX↑, Akt↓, p70S6↓, PTEN↑, TSC2↑,
751- Bor,  5-FU,    Cytotoxic and Apoptotic Effects of the Combination of Borax (Sodium Tetraborate) and 5-Fluorouracil on DLD-1 Human Colorectal Adenocarcinoma Cell Line
- in-vitro, CRC, DLD1
Apoptosis↑,
752- Bor,    The Potential Role of Boron in the Modulation of Gut Microbiota Composition: An In Vivo Pilot Study
GutMicro↑,
753- Bor,    Boron Intake and decreased risk of mortality in kidney transplant recipients
OS↑,
707- Bor,    Cytotoxic and apoptotic effects of boron compounds on leukemia cell line
- in-vitro, AML, HL-60
Apoptosis↑,
755- Bor,    https://aacrjournals.org/cancerres/article/67/9_Supplement/4220/535557/Boric-acid-induces-apoptosis-in-both-prostate-and
- in-vitro, Pca, DU145 - in-vitro, PC, PC3
TumCG↓, Apoptosis↑,
756- Bor,    Evaluation of Boric Acid Treatment on microRNA‐127‐5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells
- in-vitro, BC, MCF7
COL1A1↓, Vim↓, miR-127-5p↑, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑,
757- Bor,    Phenylboronic acid is a more potent inhibitor than boric acid of key signaling networks involved in cancer cell migration
- in-vitro, Pca, DU145 - in-vitro, Nor, RWPE-1
Rho↓, Rac1↓, Cdc42↓, *eff↑,
758- Bor,    Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
- Human, NA, NA
*hs-CRP↓, *TNF-α↓, *SHBG↓, *DHT↑, *cortisol↑, *VitD↑, *BioAv↑, *Inflam↓,
759- Bor,    The nutritional and metabolic effects of boron in humans and animals
- in-vivo, NA, NA
DHT↑, VitD↑, HDL↓,
760- Bor,    Therapeutic Efficacy of Boric Acid Treatment on Brain Tissue and Cognitive Functions in Rats with Experimental Alzheimer’s Disease
- in-vivo, AD, NA
*memory↑, *ROS↓, *GSH↑, *Aβ↓, *Inflam↓, *MMP↑, *lipid-P↓, *Ca+2↓, *cognitive↑, *TOS↓,
761- Bor,    Prevalence of Prostate Cancer in High Boron-Exposed Population: A Community-Based Study
- Study, BPH, NA
other↓,
762- Bor,    Mechanism of boric acid cytotoxicity in breast cancer cell lines
- in-vitro, BC, MCF7 - in-vitro, BC, ZR-75-1
TumCG↓,
763- Bor,    Investigation of The Apoptotic and Antiproliferative Effects of Boron on CCL-233 Human Colon Cancer Cells
- in-vitro, Colon, CCl233
TumCP↓, PARP↓, VEGF↓,
764- Bor,    Effect of Tumor Microenvironment on Selective Uptake of Boric Acid in HepG2 Human Hepatoma Cells
- in-vitro, Liver, HepG2
BioAv↑,
765- Bor,    High concentrations of boric acid induce autophagy in cancer cell lines
p62↓, LC3II↑, TumAuto↑,
766- Bor,    In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration
- in-vitro, Liver, HepG2
TumCCA↑, DNAdam↑, Apoptosis↑,
767- Bor,    Boric acid induces cytoplasmic stress granule formation, eIF2α phosphorylation, and ATF4 in prostate DU-145 cells
- in-vitro, Pca, DU145
ER Stress↑, eIF2α↑, GRP78/BiP↑, ATF4↑,
768- Bor,    In vitro and in vivo antitumour effects of phenylboronic acid against mouse mammary adenocarcinoma 4T1 and squamous carcinoma SCCVII cells
- in-vitro, BC, 4T1
TumCP↓,
706- Bor,    Boron supplementation inhibits the growth and local expression of IGF-1 in human prostate adenocarcinoma (LNCaP) tumors in nude mice
- in-vivo, Pca, LNCaP
TumVol↓, IGF-1↓, PSA↓,
737- Bor,    Boric Acid Activation of eIF2α and Nrf2 Is PERK Dependent: a Mechanism that Explains How Boron Prevents DNA Damage and Enhances Antioxidant Statu
- in-vitro, Pca, DU145
Risk↓, p‑eIF2α↑, ATF4↑, GADD34↑,
738- Bor,    Borax induces ferroptosis of glioblastoma by targeting HSPA5/NRF2/GPx4/GSH pathways
- in-vitro, GBM, U251 - in-vitro, GBM, A172 - in-vitro, Nor, SVGp12
TumCP↓, GPx4↓, GSH↓, HSP70/HSPA5↓, NRF2↓, MDA↑, Casp3↑, Casp7↑, Ferroptosis↑, selectivity↑,
708- Bor,    Boron containing compounds as protease inhibitors
PSA↓,
709- Bor,    Cellular changes in boric acid-treated DU-145 prostate cancer cells
- in-vitro, Pca, DU145
Cyc↓, MAPK↓, TumCMig↓, LAMP2↓, p‑ERK⇅, TumCM/A↑,
710- Bor,    Boric acid inhibits stored Ca2+ release in DU-145 prostate cancer cells
- in-vitro, Pca, DU145
NAD↓, TumCP↓, CD38↑, Ca+2↓,
711- Bor,    Receptor Activated Ca2+ Release Is Inhibited by Boric Acid in Prostate Cancer Cells
- in-vitro, Pca, DU145
Ca+2↓,
712- Bor,    Boron concentrations in selected foods from borate-producing regions in Turkey
- Analysis, NA, NA
Risk↓,
713- Bor,    Effects of dietary boron on cervical cytopathology and on micronucleus frequency in exfoliated buccal cells
- Analysis, NA, NA
Risk↓,
714- Bor,    Dietary Boron and Hormone Replacement Therapy as Risk Factors for Lung Cancer in Women
- Analysis, NA, NA
Risk↓,
715- Bor,    Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1alpha inhibitors
- in-vitro, Pca, HeLa
Hif1a↓,
716- Bor,    Sugar-borate esters--potential chemical agents in prostate cancer chemoprevention
TumCG↓, Apoptosis↑,
717- Bor,  PacT,    Boric acid as a protector against paclitaxel genotoxicity
- in-vitro, NA, NA
ChemoSideEff↓,
718- Bor,    Boric Acid Exhibits Anticancer Properties in Human Endometrial Cancer Ishikawa Cells
- in-vitro, NA, NA
OSI↑, TNF-α↓, IL1↓, Casp3↑, Apoptosis↑, TOS↑,
719- Bor,    Boric Acid Affects Cell Proliferation, Apoptosis, and Oxidative Stress in ALL Cells
- in-vitro, Var, NA
Apoptosis↑, miR-21↓, TOS↓,
720- Bor,    High Concentrations of Boric Acid Trigger Concentration-Dependent Oxidative Stress, Apoptotic Pathways and Morphological Alterations in DU-145 Human Prostate Cancer Cell Line
- in-vitro, Pca, DU145
ROS↑, TumCG↓, Apoptosis↑,
721- Bor,    Polymers Based on Phenyl Boric Acid in Tumor-Targeted Therapy
- Analysis, NA, NA
SA↓,
723- Bor,    Boric acid suppresses cell proliferation by TNF signaling pathway mediated apoptosis in SW-480 human colon cancer line
- in-vitro, Colon, SW480
Apoptosis↑, TNF-α↝,
722- Bor,    Boric acid as a promising agent in the treatment of ovarian cancer: Molecular mechanisms
- in-vitro, Ovarian, MDAH-2774
TumCP↓, TumCI↓, TumCMig↓, Apoptosis↑, ROS↑, miR-21↓, miR-130a↓, Casp8∅, Casp10∅, cycD1/CCND1∅, CDK6∅, CDK4∅, FADD∅, DR4∅, DR5∅,
736- Bor,    Evaluation of Boric Acid Treatment on microRNA-127-5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells
- in-vitro, BC, MCF7
miR-126↑, COL1A1↓, Vim↓, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑, miR-127-5p↑,
735- Bor,    Boric Acid Alters the Expression of DNA Double Break Repair Genes in MCF-7-Derived Breast Cancer Stem Cells
- in-vitro, BC, NA
BRCA1↑, BRCA2↑, ATM↓,
734- Bor,    Boric Acid Affects the Expression of DNA Double-Strand Break Repair Factors in A549 Cells and A549 Cancer Stem Cells: An In Vitro Study
- in-vitro, Lung, A549
ATM↓, Casp3↑, E-cadherin↑,
733- Bor,    The analysis of boric acid effect on epithelial-mesenchymal transition of CD133 + CD117 + lung cancer stem cells
- in-vitro, Lung, NA
Snail↑, ITGB1↑, ITGA5↑, COL1A1↓, LAMA5↑, MMP3↓, Vim↓, E-cadherin↑, EMT↓, Zeb1↑,

Showing Research Papers: 1601 to 1650 of 7372
Prev Page 33 of 148 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7372

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

Catalase↑, 1,   Ferroptosis↑, 1,   GPx↑, 1,   GPx4↓, 1,   GSH↓, 1,   HDL↓, 1,   MDA↓, 1,   MDA↑, 1,   NRF2↓, 1,   OSI↑, 1,   ROS↑, 3,   SOD↑, 1,   TOS↓, 1,   TOS↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

LAT↓, 1,   NAD↓, 1,   PSMB5↓, 1,   TumCM/A↑, 1,  

Cell Death(tgid=5)

Akt↓, 1,   APAF1↑, 1,   Apoptosis↑, 11,   BAX↑, 3,   Bcl-2↓, 4,   Bcl-xL↓, 1,   Casp10∅, 1,   Casp3↑, 7,   Casp7↑, 1,   Casp8∅, 1,   Casp9↑, 2,   DR4∅, 1,   DR5∅, 1,   FADD∅, 1,   Ferroptosis↑, 1,   GADD34↑, 1,   MAPK↓, 1,   miR-127-5p↑, 2,   NOXA↑, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6)

p70S6↓, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7)

miR-21↓, 3,   other↓, 1,  

Protein Folding & ER Stress(tgid=8)

ATF6↑, 1,   CHOP/DDIT3↑, 1,   eIF2α↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 1,   ER Stress↝, 1,   GRP78/BiP↑, 2,   HSP70/HSPA5↓, 1,  

Autophagy & Lysosomes(tgid=9)

LAMP2↓, 1,   LC3II↑, 1,   p62↓, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10)

ATM↓, 2,   p‑ATM↑, 1,   BRCA1↑, 1,   BRCA2↑, 1,   DNAdam↑, 1,   P53↓, 1,   p‑P53↑, 1,   PARP↓, 2,  

Cell Cycle & Senescence(tgid=11)

CDK4∅, 1,   Cyc↓, 1,   cycD1/CCND1∅, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12)

EMT↓, 1,   p‑ERK⇅, 1,   IGF-1↓, 2,   PTEN↑, 1,   TumCG↓, 5,  

Migration(tgid=13)

Ca+2↓, 3,   CD38↑, 1,   Cdc42↓, 2,   CDH1↑, 2,   COL1A1↓, 3,   E-cadherin↑, 2,   ITGA5↑, 3,   ITGB1↑, 3,   LAMA5↑, 3,   miR-130a↓, 1,   MMP3↓, 1,   Rac1↓, 1,   Rho↓, 2,   SA↓, 1,   Snail↑, 3,   TumCI↓, 1,   TumCMig↓, 2,   TumCP↓, 5,   Vim↓, 3,   Zeb1↑, 3,  

Angiogenesis & Vasculature(tgid=14)

ATF4↑, 2,   Hif1a↓, 1,   miR-126↑, 1,   VEGF↓, 2,  

Barriers & Transport(tgid=15)

SLC12A5↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

IL1↓, 1,   IL10↑, 1,   IL6↓, 1,   PSA↓, 3,   TNF-α↓, 2,   TNF-α↝, 1,   VitD↑, 1,  

Hormonal & Nuclear Receptors(tgid=20)

AR↓, 1,   CDK6∅, 1,   DHT↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   eff↑, 3,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22)

AR↓, 1,   BRCA1↑, 1,   GutMicro↑, 1,   IL6↓, 1,   PSA↓, 3,   VitD↑, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   ChemoSideEff↓, 1,   OS↑, 1,   Risk↓, 5,   TumVol↓, 2,  
Total Targets: 120

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

GSH↑, 1,   lipid-P↓, 1,   ROS↓, 1,   TOS↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

MMP↑, 1,  

Migration(tgid=13)

Ca+2↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 2,   TNF-α↓, 1,   VitD↑, 1,  

Protein Aggregation(tgid=19)

Aβ↓, 1,  

Hormonal & Nuclear Receptors(tgid=20)

cortisol↑, 1,   DHT↑, 1,   SHBG↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   eff↓, 1,   eff↑, 1,  

Clinical Biomarkers(tgid=22)

hs-CRP↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23)

cognitive↑, 1,   memory↑, 1,   toxicity↓, 3,  
Total Targets: 21

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

Home Page