Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
4623- Bor,    Proteomic insights into the anti-cancer mechanisms of boron-based compounds in prostate cancer
- Review, Pca, NA
AntiCan↑,
4622- Bor,    Boron Level in the Prostate of the Normal Human: A Systematic Review
- Review, BPH, NA
Dose↝,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
697- Bor,    Boron-containing compounds as preventive and chemotherapeutic agents for cancer
- Review, NA, NA
serineP↓, NADHdeh↓, Apoptosis↑,
698- Bor,    Boron deprivation decreases liver S-adenosylmethionine and spermidine and increases plasma homocysteine and cysteine in rats
- in-vitro, NA, NA
SAM-e↑,
699- Bor,    Boric Acid Alleviates Gastric Ulcer by Regulating Oxidative Stress and Inflammation-Related Multiple Signaling Pathways
- in-vivo, NA, NA
*ROS↓, *MDA↓, *TNF-α↓, *IL6↓, *JAK2↓, *STAT3↓, *AMPK↑, *Sema3A/PlexinA1↑,
700- Bor,    Diadenosine phosphates and S-adenosylmethionine: novel boron binding biomolecules detected by capillary electrophoresis
- Analysis, NA, NA
SAM-e↝,
701- Bor,    Dietary boron intake and prostate cancer risk
- Analysis, NA, NA
Risk↓,
702- Bor,  GEN,  SeMet,  Rad,    Evaluation of ecological and in vitro effects of boron on prostate cancer risk (United States)
- Analysis, NA, NA
Risk↓, TumCMig↓, Bcl-2↓,
703- Bor,    Boron intake and prostate cancer risk
- Analysis, NA, NA
Risk∅,
704- Bor,    Inhibition of the enzymatic activity of prostate-specific antigen by boric acid and 3-nitrophenyl boronic acid
- in-vitro, Pca, NA
PSA↓,
705- Bor,    Boric acid inhibits human prostate cancer cell proliferation
- in-vitro, Pca, DU145 - in-vitro, Pca, LNCaP
TumCP↓,
754- Bor,  HRT,    Dietary Boron and Hormone Replacement Therapy as Risk Factors for Lung Cancer in Women
- Analysis, NA, NA
Risk↓,
739- Bor,    Borax regulates iron chaperone- and autophagy-mediated ferroptosis pathway in glioblastoma cells
- in-vitro, GBM, U87MG - in-vitro, Nor, HMC3
TumCG↓, TumCP↓, TumCCA↑, PCBP1↓, GSH↓, GPx4↓, Beclin-1↑, MDA↑, ACSL4↑, Casp3↑, Casp7↑, Ferroptosis↑, *toxicity↓,
740- Bor,    Anti-cancer effect of boron derivatives on small-cell lung cancer
- in-vitro, Lung, DMS114 - in-vitro, Nor, MRC-5
Apoptosis↑, TumCCA↑, P53↑, Casp3↑, *toxicity↓,
741- Bor,    Boron Derivatives Inhibit the Proliferation of Breast Cancer Cells and Affect Tumor-Specific T Cell Activity In Vitro by Distinct Mechanisms
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
MOB1↓, PD-L1↑, p‑YAP/TEAD↝, IFN-γ↓, sFasL↑, Perforin↓, GranA↓, GranB↓, GNLY↓, PD-1↑,
742- Bor,    In Vitro Effects of Boric Acid on Cell Cycle, Apoptosis, and miRNAs in Medullary Thyroid Cancer Cells
- in-vitro, Thyroid, NA
NOXA↑, APAF1↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, Bcl-xL↓, miR-21↓,
743- Bor,    Boric Acid (Boron) Attenuates AOM-Induced Colorectal Cancer in Rats by Augmentation of Apoptotic and Antioxidant Mechanisms
- in-vitro, CRC, NA
BAX↑, Bcl-2↓, GPx↑, SOD↑, Catalase↑, MDA↓, TNF-α↓, IL6↓, IL10↑,
744- Bor,    Borax affects cellular viability by inducing ER stress in hepatocellular carcinoma cells by targeting SLC12A5
- in-vitro, HCC, HepG2 - in-vitro, Nor, HL7702
TumCCA↑, SLC12A5↓, ATF6↑, CHOP↑, GRP78/BiP↑, Casp3↑, ER Stress↝, *toxicity↓, *eff↓,
745- Bor,    Investigation of cytotoxic antiproliferative and antiapoptotic effects of nanosized boron phosphate filled sodium alginate composite on glioblastoma cancer cells
- in-vitro, GBM, U87MG - in-vitro, Nor, L929 - in-vitro, GBM, T98G
TumCD↑, *toxicity↓,
746- Bor,    Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
- Review, NA, NA
eff↑, *toxicity↓, ROS↑, LAT↓, AntiCan↑, AR↓, PSMB5↓, IGF-1↓, PSA↓, TumVol↓, eff↑, Rho↓, Cdc42↓, Ca+2↓, eff↑,
747- Bor,    Growing Evidence for Human Health Benefits of Boron
- Review, NA, NA
TumCG↓, Risk↓,
748- Bor,    A Study on the Anticarcinogenic Effects of Calcium Fructoborate
- in-vitro, BC, MDA-MB-231
p‑ATM↑, p‑P53↑, Casp9↑, PARP↓, VEGF↓, Casp3↑,
749- Bor,    Comparative effects of boric acid and calcium fructoborate on breast cancer cells
P53↓, Bcl-2↓, Casp3↑, Apoptosis↑,
750- Bor,    Calcium fructoborate regulate colon cancer (Caco-2) cytotoxicity through modulation of apoptosis
- in-vitro, CRC, Caco-2
Bcl-2↓, BAX↑, Akt↓, p70S6↓, PTEN↑, TSC2↑,
751- Bor,  5-FU,    Cytotoxic and Apoptotic Effects of the Combination of Borax (Sodium Tetraborate) and 5-Fluorouracil on DLD-1 Human Colorectal Adenocarcinoma Cell Line
- in-vitro, CRC, DLD1
Apoptosis↑,
752- Bor,    The Potential Role of Boron in the Modulation of Gut Microbiota Composition: An In Vivo Pilot Study
GutMicro↑,
753- Bor,    Boron Intake and decreased risk of mortality in kidney transplant recipients
OS↑,
707- Bor,    Cytotoxic and apoptotic effects of boron compounds on leukemia cell line
- in-vitro, AML, HL-60
Apoptosis↑,
755- Bor,    https://aacrjournals.org/cancerres/article/67/9_Supplement/4220/535557/Boric-acid-induces-apoptosis-in-both-prostate-and
- in-vitro, Pca, DU145 - in-vitro, PC, PC3
TumCG↓, Apoptosis↑,
756- Bor,    Evaluation of Boric Acid Treatment on microRNA‐127‐5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells
- in-vitro, BC, MCF-7
COL1A1↓, Vim↓, miR-127-5p↑, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑,
757- Bor,    Phenylboronic acid is a more potent inhibitor than boric acid of key signaling networks involved in cancer cell migration
- in-vitro, Pca, DU145 - in-vitro, Nor, RWPE-1
Rho↓, Rac1↓, Cdc42↓, *eff↑,
758- Bor,    Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
- Human, NA, NA
*hs-CRP↓, *TNF-α↓, *SHBG↓, *DHT↑, *cortisol↑, *VitD↑, *BioAv↑, *Inflam↓,
759- Bor,    The nutritional and metabolic effects of boron in humans and animals
- in-vivo, NA, NA
DHT↑, VitD↑, HDL↓,
760- Bor,    Therapeutic Efficacy of Boric Acid Treatment on Brain Tissue and Cognitive Functions in Rats with Experimental Alzheimer’s Disease
- in-vivo, AD, NA
*memory↑, *ROS↓, *GSH↑, *Aβ↓, *Inflam↓, *MMP↑, *lipid-P↓, *Ca+2↓, *cognitive↑, *TOS↓,
761- Bor,    Prevalence of Prostate Cancer in High Boron-Exposed Population: A Community-Based Study
- Study, BPH, NA
other↓,
762- Bor,    Mechanism of boric acid cytotoxicity in breast cancer cell lines
- in-vitro, BC, MCF-7 - in-vitro, BC, ZR-75-1
TumCG↓,
763- Bor,    Investigation of The Apoptotic and Antiproliferative Effects of Boron on CCL-233 Human Colon Cancer Cells
- in-vitro, Colon, CCl233
TumCP↓, PARP↓, VEGF↓,
764- Bor,    Effect of Tumor Microenvironment on Selective Uptake of Boric Acid in HepG2 Human Hepatoma Cells
- in-vitro, Liver, HepG2
BioAv↑,
765- Bor,    High concentrations of boric acid induce autophagy in cancer cell lines
p62↓, LC3II↑, TumAuto↑,
766- Bor,    In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration
- in-vitro, Liver, HepG2
TumCCA↑, DNAdam↑, Apoptosis↑,
767- Bor,    Boric acid induces cytoplasmic stress granule formation, eIF2α phosphorylation, and ATF4 in prostate DU-145 cells
- in-vitro, Pca, DU145
ER Stress↑, eIF2α↑, GRP78/BiP↑, ATF4↑,
768- Bor,    In vitro and in vivo antitumour effects of phenylboronic acid against mouse mammary adenocarcinoma 4T1 and squamous carcinoma SCCVII cells
- in-vitro, BC, 4T1
TumCP↓,
706- Bor,    Boron supplementation inhibits the growth and local expression of IGF-1 in human prostate adenocarcinoma (LNCaP) tumors in nude mice
- in-vivo, Pca, LNCaP
TumVol↓, IGF-1↓, PSA↓,
737- Bor,    Boric Acid Activation of eIF2α and Nrf2 Is PERK Dependent: a Mechanism that Explains How Boron Prevents DNA Damage and Enhances Antioxidant Statu
- in-vitro, Pca, DU145
Risk↓, p‑eIF2α↑, ATF4↑, GADD34↑,
738- Bor,    Borax induces ferroptosis of glioblastoma by targeting HSPA5/NRF2/GPx4/GSH pathways
- in-vitro, GBM, U251 - in-vitro, GBM, A172 - in-vitro, Nor, SVGp12
TumCP↓, GPx4↓, GSH↓, HSP70/HSPA5↓, NRF2↓, MDA↑, Casp3↑, Casp7↑, Ferroptosis↑, selectivity↑,
708- Bor,    Boron containing compounds as protease inhibitors
PSA↓,
709- Bor,    Cellular changes in boric acid-treated DU-145 prostate cancer cells
- in-vitro, Pca, DU145
Cyc↓, MAPK↓, TumCMig↓, LAMP2↓, p‑ERK⇅, TumCM/A↑,
710- Bor,    Boric acid inhibits stored Ca2+ release in DU-145 prostate cancer cells
- in-vitro, Pca, DU145
NAD↓, TumCP↓, CD38↑, Ca+2↓,
711- Bor,    Receptor Activated Ca2+ Release Is Inhibited by Boric Acid in Prostate Cancer Cells
- in-vitro, Pca, DU145
Ca+2↓,

Showing Research Papers: 1601 to 1650 of 6604
Prev Page 33 of 133 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6604

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↑, 1,   Ferroptosis↑, 2,   GPx↑, 1,   GPx4↓, 2,   GSH↓, 2,   HDL↓, 1,   MDA↓, 1,   MDA↑, 2,   NADHdeh↓, 1,   NRF2↓, 1,   ROS↑, 1,   SAM-e↑, 1,   SAM-e↝, 1,   SOD↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACSL4↑, 1,   LAT↓, 1,   NAD↓, 1,   PSMB5↓, 1,   TumCM/A↑, 1,  

Cell Death ⓘ

Akt↓, 1,   APAF1↑, 1,   Apoptosis↑, 8,   BAX↑, 3,   Bcl-2↓, 5,   Bcl-xL↓, 1,   Casp3↑, 7,   Casp7↑, 2,   Casp9↑, 2,   Ferroptosis↑, 2,   GADD34↑, 1,   GranA↓, 1,   GranB↓, 1,   MAPK↓, 1,   miR-127-5p↑, 1,   NOXA↑, 1,   Perforin↓, 1,   sFasL↑, 1,   TumCD↑, 1,   p‑YAP/TEAD↝, 1,  

Kinase & Signal Transduction ⓘ

p70S6↓, 1,   TSC2↑, 1,  

Transcription & Epigenetics ⓘ

miR-21↓, 1,   other↓, 1,  

Protein Folding & ER Stress ⓘ

ATF6↑, 1,   CHOP↑, 1,   eIF2α↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 1,   ER Stress↝, 1,   GRP78/BiP↑, 2,   HSP70/HSPA5↓, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,   LAMP2↓, 1,   LC3II↑, 1,   p62↓, 1,   TumAuto↑, 1,  

DNA Damage & Repair ⓘ

p‑ATM↑, 1,   DNAdam↑, 1,   P53↓, 1,   P53↑, 1,   p‑P53↑, 1,   PARP↓, 2,  

Cell Cycle & Senescence ⓘ

Cyc↓, 2,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State ⓘ

p‑ERK⇅, 1,   HDAC↓, 1,   IGF-1↓, 3,   PTEN↑, 1,   TumCG↓, 4,  

Migration ⓘ

Ca+2↓, 3,   CD38↑, 1,   Cdc42↓, 2,   CDH1↑, 1,   COL1A1↓, 1,   ITGA5↑, 1,   ITGB1↑, 1,   LAMA5↑, 1,   MOB1↓, 1,   PCBP1↓, 1,   Rac1↓, 1,   Rho↓, 2,   serineP↓, 1,   Snail↑, 1,   TumCMig↓, 3,   TumCP↓, 6,   Vim↓, 1,   Zeb1↑, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   ATF4↑, 2,   HIF-1↓, 1,   VEGF↓, 2,  

Barriers & Transport ⓘ

SLC12A5↓, 1,  

Immune & Inflammatory Signaling ⓘ

GNLY↓, 1,   IFN-γ↓, 1,   IL10↑, 1,   IL6↓, 1,   PD-1↑, 1,   PD-L1↑, 1,   PSA↓, 5,   TNF-α↓, 1,   VitD↑, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 1,   DHT↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   Dose↝, 1,   eff↑, 3,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

AR↓, 1,   GutMicro↑, 1,   IL6↓, 1,   PD-L1↑, 1,   PSA↓, 5,   VitD↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 3,   OS↑, 1,   Risk↓, 6,   Risk∅, 1,   TumVol↓, 3,  
Total Targets: 118

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

Catalase↑, 1,   GPx↑, 1,   GSH↑, 1,   lipid-P↓, 1,   MDA↓, 1,   ROS↓, 2,   SAM-e↑, 1,   SOD↑, 1,   TOS↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↝, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 1,   NAD↝, 1,  

Proliferation, Differentiation & Cell State ⓘ

STAT3↓, 1,  

Migration ⓘ

Ca+2↓, 1,   Ca+2↝, 1,   Sema3A/PlexinA1↑, 1,   serineP↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL6↓, 1,   Inflam↓, 3,   JAK2↓, 1,   TNF-α↓, 3,   VitD↑, 2,  

Protein Aggregation ⓘ

Aβ↓, 1,  

Hormonal & Nuclear Receptors ⓘ

cortisol↑, 1,   DHT↑, 1,   SHBG↓, 1,   testos↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   Dose↑, 1,   Dose↝, 1,   eff↓, 1,   eff↑, 2,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

BMD↑, 1,   BMPs↑, 1,   Calcium↑, 1,   hs-CRP↓, 2,   IL6↓, 1,   Mag↑, 1,   VitD↑, 2,  

Functional Outcomes ⓘ

chemoP↑, 1,   chemoPv↑, 1,   ChemoSideEff↓, 1,   cognitive↑, 2,   memory↑, 2,   neuroP↑, 1,   Risk↓, 1,   toxicity↓, 5,  
Total Targets: 49

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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