| Source: |
| Type: type of cell death |
| Situation in which a cell actively pursues a course toward death upon receiving certain stimuli. Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die. |
| 8874- | MOR, | The anticarcinogenic and anticancer effects of the dietary flavonoid, morin: Current status, challenges, and future perspectives |
| - | Review, | Var, | NA |
| 8868- | MOR, | PacT, | Synergistic effect of morin and paclitaxel impedes cell proliferation through PI3K/AKT/STAT3 signaling axis inhibition in gastric cancer |
| - | in-vitro, | GC, | HGC27 |
| 8865- | MOR, | Morin impedes Yap nuclear translocation and fosters apoptosis through suppression of Wnt/β-catenin and NF-κB signaling in Mst1 overexpressed HepG2 cells |
| - | in-vitro, | Liver, | HepG2 |
| 8863- | MOR, | Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect |
| - | in-vitro, | Colon, | SW48 |
| 8862- | MOR, | The flavonoid morin from Moraceae induces apoptosis by modulation of Bcl-2 family members and Fas receptor in HCT 116 cells |
| - | in-vitro, | CRC, | HCT116 |
| 8893- | MOR, | Flavonoid morin inhibits proliferation and induces apoptosis of melanoma cells by regulating reactive oxygen species, Sp1 and Mcl-1 |
| - | in-vitro, | Melanoma, | NA |
| 8887- | MOR, | Morin hydrate ameliorates Di-2-ethylhexyl phthalate (DEHP) induced hepatotoxicity in a mouse model via TNF-α and NF-κβ signaling |
| - | in-vivo, | Nor, | NA |
| 8882- | MOR, | Cisplatin, | Morin hydrate protects against cisplatin-induced testicular toxicity by modulating ferroptosis and steroidogenesis genes' expression and upregulating Nrf2/Heme oxygenase-1 |
| - | in-vivo, | Nor, | NA |
| 8880- | MOR, | Morin, a Natural Flavonoid, Activates the PINK1/Parkin Pathway to Induce Mitophagy, Promote Apoptosis, and Suppress Cancer Stemness in Pancreatic Cancer |
| - | in-vitro, | PC, | NA |
| 8879- | MOR, | doxoR, | Synergistic Effects of Morin and Doxorubicin Overcome Chemoresistance in Ovarian Cancer: Preclinical Insights From in vitro and in vivo Models |
| - | vitro+vivo, | Ovarian, | OVCAR-3 | - | NA, | Melanoma, | A2780S |
| 8878- | MOR, | Investigating the Effects of Morin and Aminoimidazole Carboxamide Ribonucleotide on the AMPK/mTOR/ULK1 Signaling Pathway in Breast Cancer Cell Line (MCF-7) |
| - | in-vitro, | BC, | MCF7 |
| 8919- | MP, | Antineoplastic Effects of Mucuna pruriens Against Human Colorectal Adenocarcinoma |
| - | in-vitro, | CRC, | COLO205 |
| 8780- | MSM, | Methylsulfonylmethane Induces Cell Cycle Arrest and Apoptosis, and Suppresses the Stemness Potential of HT-29 Cells |
| - | in-vitro, | CRC, | HT-29 |
| 8775- | MSM, | Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells |
| - | Review, | Colon, | HCT116 |
| 8774- | MSM, | Methylsulfonylmethane Induces G1 Arrest and Mitochondrial Apoptosis in YD-38 Gingival Cancer Cells |
| - | in-vitro, | Oral, | YD-38 |
| 8773- | MSM, | Methylsulfonylmethane (organic sulfur) induces apoptosis and decreases invasiveness of prostate cancer cells |
| - | in-vitro, | Pca, | LNCaP | - | in-vitro, | Pca, | PC3 | - | in-vitro, | Pca, | DU145 |
| 8771- | MSM, | Methylsulfonylmethane induces caspase-dependent apoptosis in acute myeloid leukemia cell lines |
| - | in-vitro, | lymphoma, | U937 | - | in-vitro, | AML, | HL-60 |
| 8772- | MSM, | doxoR, | Methylsulfonylmethane sensitizes endometrial cancer cells to doxorubicin |
| - | in-vitro, | EC, | NA |
| 8766- | MSM, | Methylsulfonylmethane suppresses hepatic tumor development through activation of apoptosis |
| - | vitro+vivo, | Liver, | HepG2 | - | in-vitro, | Liver, | HUH7 |
| 3847- | MSM, | Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement |
| - | Review, | Arthritis, | NA |
| 8809- | MT/VAE, | Cisplatin, | Synergistic Effects of Mistletoe Lectin and Cisplatin on Triple-Negative Breast Cancer Cells: Insights from 2D and 3D In Vitro Models |
| - | in-vitro, | BC, | MDA-MB-231 |
| 8807- | MT/VAE, | Mistletoe Extracts Inhibit Progressive Growth of Prostate Cancer Cells |
| - | in-vitro, | Pca, | PC3 | - | in-vitro, | Pca, | DU145 | - | in-vitro, | GBM, | LNCaP |
| 8804- | MT/VAE, | Activation of caspase cascades in Korean mistletoe (Viscum album var. coloratum) lectin-II-induced apoptosis of human myeloleukemic U937 cells |
| - | in-vitro, | lymphoma, | U937 |
| 8936- | MushCha, | Inonotus obliquus polysaccharides induces apoptosis of lung cancer cells and alters energy metabolism via the LKB1/AMPK axis |
| - | vitro+vivo, | Lung, | LLC1 |
| 8937- | MushCha, | Effects of Inonotus obliquus Polysaccharides on Proliferation, Invasion, Migration, and Apoptosis of Osteosarcoma Cells |
| - | in-vitro, | OS, | MG63 | - | in-vitro, | OS, | U2OS |
| 8938- | MushCha, | Bioactivity-based analysis and chemical characterization of cytotoxic constituents from Chaga mushroom (Inonotus obliquus) that induce apoptosis in human lung adenocarcinoma cells |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H1299 | - | in-vitro, | Lung, | Calu-6 |
| 1182- | MushCha, | Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HT-29 | - | in-vitro, | CRC, | SW-620 | - | in-vitro, | CRC, | DLD1 |
| 8968- | mushLions, | Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells |
| - | in-vitro, | lymphoma, | U937 |
| 8951- | mushLions, | Apoptotic mechanisms of gastric cancer cells induced by isolated erinacine S through epigenetic histone H3 methylation of FasL and TRAIL |
| - | vitro+vivo, | GC, | NA |
| - | vitro+vivo, | CRC, | DLD1 |
| 8954- | mushLions, | Hericium erinaceus polysaccharide-protein HEG-5 inhibits SGC-7901 cell growth via cell cycle arrest and apoptosis |
| - | in-vitro, | GC, | SGC-7901 |
| 8961- | mushLions, | A Novel Erinacine S Derivative from Hericium erinaceus Overcomes Chemoresistance in Colorectal Cancer Cells by Enhancing TRAIL/TNFR1/DR5 Expression through Histone Acetylation |
| - | in-vivo, | CRC, | NA |
| 3809- | mushLions, | The Monkey Head Mushroom and Memory Enhancement in Alzheimer's Disease |
| - | Review, | AD, | NA |
| - | vitro+vivo, | CRC, | HCT116 | - | in-vitro, | CRC, | HT-29 |
| 9302- | MushMait, | Black Maitake mushroom (Grifola frondosa) extract exerts anti-cancer effects and enhances the efficacy of chemotherapeutic drugs in 2D and 3D models of triple-negative breast cancer |
| - | in-vitro, | BC, | MDA-MB-231 |
| 116- | Myrrh, | The Role of Myrrh Metabolites in Cancer, Inflammation, and Wound Healing: Prospects for a Multi-Targeted Drug Therapy |
| - | in-vitro, | AML, | HL-60 | - | in-vitro, | AML, | K562 | - | in-vitro, | BC, | KAIMRC1 |
| 2932- | NAD, | Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment |
| - | in-vitro, | Nor, | NA |
| 1797- | NarG, | Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting β-catenin signaling pathway |
| - | in-vitro, | BC, | MDA-MB-231 |
| 1798- | NarG, | Naringenin: A potential flavonoid phytochemical for cancer therapy |
| - | Review, | Var, | NA |
| 4225- | NarG, | Naringin treatment improves functional recovery by increasing BDNF and VEGF expression, inhibiting neuronal apoptosis after spinal cord injury |
| - | in-vivo, | AD, | NA |
| 5253- | NCL, | Niclosamide: Beyond an antihelminthic drug |
| - | Review, | Var, | NA |
| 1269- | NCL, | Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway |
| - | in-vitro, | Pca, | DU145 |
| 1271- | NCL, | Niclosamide inhibits ovarian carcinoma growth by interrupting cellular bioenergetics |
| - | vitro+vivo, | Ovarian, | SKOV3 |
| 6492- | Nimb, | Review on Molecular and Chemopreventive Potential of Nimbolide in Cancer |
| - | Review, | Var, | NA |
| 6490- | Nimb, | Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer |
| - | in-vitro, | Oral, | SCC4 |
| 6489- | Nimb, | Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model |
| - | in-vivo, | Pca, | DU145 | - | in-vivo, | Pca, | LNCaP |
| 6485- | Nimb, | Limonoids from neem (Azadirachta indica A. Juss.) are potential anticancer drug candidates |
| - | Review, | Var, | NA |
| 6487- | Nimb, | Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development |
| - | Review, | Var, | NA |
| 6493- | Nimb, | Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment |
| - | in-vivo, | CRC, | HCT116 | - | vitro+vivo, | CRC, | HT29 |
| 946- | Nimb, | Nimbolide retards T cell lymphoma progression by altering apoptosis, glucose metabolism, pH regulation, and ROS homeostasis |
| - | in-vivo, | Var, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:14 State#:% Dir#:%
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