| Source: |
| Type: type of cell death |
| Situation in which a cell actively pursues a course toward death upon receiving certain stimuli. Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die. |
| 4973- | Nimb, | Nimbolide Exhibits Potent Anticancer Activity Through ROS-Mediated ER Stress and DNA Damage in Human Non-small Cell Lung Cancer Cells |
| - | in-vitro, | NSCLC, | A549 |
| 4970- | Nimb, | Insights into Nimbolide molecular crosstalk and its anticancer properties |
| - | Review, | Var, | NA |
| 4971- | Nimb, | Nimbolide, a Neem Limonoid, Is a Promising Candidate for the Anticancer Drug Arsenal |
| - | Review, | Var, | NA |
| 4972- | Nimb, | Chemopreventive and therapeutic effects of nimbolide in cancer: The underlying mechanisms |
| - | Review, | Var, | NA |
| 4974- | Nimb, | Nimbolide Induces ROS-Regulated Apoptosis and Inhibits Cell Migration in Osteosarcoma |
| - | in-vitro, | OS, | NA |
| 4975- | Nimb, | Nimbolide Induces Cell Apoptosis via Mediating ER Stress-Regulated Apoptotic Signaling in Human Oral Squamous Cell Carcinoma |
| - | in-vitro, | Oral, | NA |
| 4976- | Nimb, | Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition |
| - | vitro+vivo, | PC, | NA |
| 4977- | Nimb, | Nimbolide Inhibits SOD2 to Control Pancreatic Ductal Adenocarcinoma Growth and Metastasis |
| - | vitro+vivo, | PC, | AsPC-1 | - | in-vitro, | PC, | PANC1 |
| 4629- | OLE, | Oleuropein exhibits anticancer effects by inducing apoptosis and inhibiting cell motility in MCF7 and MDA-MB231 breast cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 | - | NA, | NA, | MCF7 |
| 4643- | OLE, | HT, | Use of Oleuropein and Hydroxytyrosol for Cancer Prevention and Treatment: Considerations about How Bioavailability and Metabolism Impact Their Adoption in Clinical Routine |
| - | Review, | Var, | NA |
| 4649- | OLEC, | Anticancer molecular mechanisms of oleocanthal |
| - | Review, | Var, | NA |
| 4648- | OLEC, | The Effect of Dietary Intervention With High-Oleocanthal and Oleacein Olive Oil in Patients With Early-Stage Chronic Lymphocytic Leukemia: A Pilot Randomized Trial |
| - | Trial, | CLL, | NA |
| 1226- | OLST, | Knockdown of PGM1 enhances anticancer effects of orlistat in gastric cancer under glucose deprivation |
| - | vitro+vivo, | GC, | NA |
| 8425- | OM, | Anti-metastatic and anti-tumor growth effects of Origanum majorana on highly metastatic human breast cancer cells: inhibition of NFκB signaling and reduction of nitric oxide production |
| - | vitro+vivo, | BC, | MDA-MB-231 |
| 8427- | OM, | Mitotic arrest and apoptosis in breast cancer cells induced by Origanum majorana extract: upregulation of TNF-α and downregulation of survivin and mutant p53 |
| - | in-vitro, | BC, | MDA-MB-231 |
| 8449- | OM, | Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties |
| - | in-vitro, | BC, | MDA-MB-231 |
| 8450- | OM, | Can Origanum be a hope for cancer treatment? A review on the potential of Origanum species in preventing and treating cancers |
| - | Review, | Var, | NA |
| 8452- | OM, | Sweet Marjoram: A Review of Ethnopharmacology, Phytochemistry, and Biological Activities |
| - | Review, | Nor, | NA |
| 1812- | Oxy, | Hyperbaric oxygen suppressed tumor progression through the improvement of tumor hypoxia and induction of tumor apoptosis in A549-cell-transferred lung cancer |
| - | in-vitro, | Lung, | A549 | - | in-vivo, | Lung, | NA | - | in-vitro, | NA, | BEAS-2B |
| 2396- | PACs, | PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma |
| - | in-vitro, | HCC, | HCCLM3 | - | in-vitro, | HCC, | SMMC-7721 cell | - | in-vitro, | HCC, | Bel-7402 | - | in-vitro, | HCC, | HUH7 | - | in-vitro, | HCC, | HepG2 | - | in-vitro, | Nor, | L02 |
| 9046- | PatchO, | Patchouli alcohol suppresses castration-resistant prostate cancer progression by inhibiting NF-κB signal pathways |
| - | in-vitro, | Pca, | DU145 | - | in-vitro, | Pca, | PC3 |
| 9047- | PatchO, | Patchouli alcohol, an essential oil of Pogostemon cablin, exhibits anti-tumorigenic activity in human colorectal cancer cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Colon, | SW480 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | PC, | Bxpc-3 | - | in-vitro, | Pca, | PC3 | - | in-vitro, | Nor, | HUVECs |
| 9049- | PatchO, | Inhibitory effects of patchouli alcohol on hepatocellular carcinoma growth through accumulation of oxidative stress and inactivation of androgen receptor signaling |
| - | vitro+vivo, | HCC, | HepG2 | - | in-vivo, | Liver, | HUH7 |
| 9052- | PatchO, | Regulatory Mechanism and Experimental Verification of Patchouli Alcohol on Gastric Cancer Cell Based on Network Pharmacology |
| - | in-vitro, | GC, | NCI-N87 | - | in-vitro, | GC, | HGC27 |
| 9055- | PatchO, | Patchouli oil ameliorates 5-fluorouracil-induced intestinal mucositis in rats via protecting intestinal barrier and regulating water transport |
| - | in-vivo, | Nor, | NA |
| 2070- | PB, | Phenylbutyrate-induced apoptosis is associated with inactivation of NF-kappaB IN HT-29 colon cancer cells |
| - | in-vitro, | CRC, | HT-29 |
| 2053- | PB, | 4-Phenyl butyric acid prevents glucocorticoid-induced osteoblast apoptosis by attenuating endoplasmic reticulum stress |
| - | in-vitro, | ostP, | 3T3 |
| 2069- | PB, | Toxic and metabolic effect of sodium butyrate on SAS tongue cancer cells: role of cell cycle deregulation and redox changes |
| - | in-vitro, | Tong, | NA |
| 2061- | PB, | Chemo, | Complementary effects of HDAC inhibitor 4-PB on gap junction communication and cellular export mechanisms support restoration of chemosensitivity of PDAC cells |
| - | in-vitro, | PC, | PANC1 | - | in-vitro, | PC, | COLO357 | - | in-vitro, | PC, | Bxpc-3 |
| 2078- | PB, | Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response |
| - | in-vitro, | CRC, | HCT116 |
| 2076- | PB, | Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HT29 |
| 2048- | PB, | Sodium Phenylbutyrate Inhibits Tumor Growth and the Epithelial-Mesenchymal Transition of Oral Squamous Cell Carcinoma In Vitro and In Vivo |
| - | in-vitro, | OS, | CAL27 | - | in-vitro, | Oral, | HSC3 | - | in-vitro, | OS, | SCC4 | - | in-vivo, | NA, | NA |
| 2046- | PB, | Sodium butyrate promotes apoptosis in breast cancer cells through reactive oxygen species (ROS) formation and mitochondrial impairment |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-468 | - | in-vitro, | Nor, | MCF10 |
| 2421- | PB, | Sodium butyrate inhibits aerobic glycolysis of hepatocellular carcinoma cells via the c‐myc/hexokinase 2 pathway |
| - | in-vitro, | HCC, | HCCLM3 | - | in-vivo, | NA, | NA | - | in-vitro, | HCC, | Bel-7402 | - | in-vitro, | HCC, | SMMC-7721 cell | - | in-vitro, | Nor, | L02 |
| 998- | PB, | Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect |
| - | in-vivo, | Var, | NA |
| 1672- | PBG, | The Potential Use of Propolis as an Adjunctive Therapy in Breast Cancers |
| - | Review, | BC, | NA |
| 1673- | PBG, | An Insight into Anticancer Effect of Propolis and Its Constituents: A Review of Molecular Mechanisms |
| - | Review, | Var, | NA |
| 1668- | PBG, | Propolis: A Detailed Insight of Its Anticancer Molecular Mechanisms |
| - | Review, | Var, | NA |
| 1675- | PBG, | Portuguese Propolis Antitumoral Activity in Melanoma Involves ROS Production and Induction of Apoptosis |
| - | in-vitro, | Melanoma, | A375 | - | in-vitro, | Melanoma, | WM983B |
| 1684- | PBG, | Antitumor Activity of Chinese Propolis in Human Breast Cancer MCF-7 and MDA-MB-231 Cells |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | Nor, | HUVECs |
| 1660- | PBG, | Emerging Adjuvant Therapy for Cancer: Propolis and its Constituents |
| - | Review, | Var, | NA |
| 1664- | PBG, | Anticancer Activity of Propolis and Its Compounds |
| - | Review, | Var, | NA |
| 1666- | PBG, | Molecular and Cellular Mechanisms of Propolis and Its Polyphenolic Compounds against Cancer |
| - | Review, | Var, | NA |
| 1667- | PBG, | Ethanolic extract of Brazilian green propolis sensitizes prostate cancer cells to TRAIL-induced apoptosis |
| - | in-vitro, | Pca, | LNCaP |
| 8983- | PCorn, | Purple corn color suppresses Ras protein level and inhibits 7,12‐dimethylbenz[a]anthracene‐induced mammary carcinogenesis in the rat |
| - | in-vivo, | BC, | NA |
| 8989- | PCorn, | Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats |
| - | in-vivo, | BPH, | NA |
| - | in-vitro, | Pca, | DU145 |
| 4946- | PEITC, | Phenethyl Isothiocyanate Inhibits Oxidative Phosphorylation to Trigger Reactive Oxygen Species-mediated Death of Human Prostate Cancer Cells |
| - | in-vitro, | Pca, | LNCaP | - | in-vitro, | Pca, | PC3 |
| 4947- | PEITC, | Phenethyl Isothiocyanate (PEITC) Inhibits the Growth of Human Oral Squamous Carcinoma HSC-3 Cells through G0/G1 Phase Arrest and Mitochondria-Mediated Apoptotic Cell Death |
| - | in-vitro, | Oral, | HSC3 |
| 4949- | PEITC, | Phenethyl Isothiocyanate Exposure Promotes Oxidative Stress and Suppresses Sp1 Transcription Factor in Cancer Stem Cells |
| - | in-vitro, | Cerv, | HeLa |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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