| 1230- | CA, | Caff, | Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 | - | Human, | NA, | NA |
| 1207- | CA, | PacT, | Caffeine inhibits the anticancer activity of paclitaxel via down-regulation of α-tubulin acetylation |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Cerv, | HeLa |
| 1651- | CA, | PBG, | Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer |
| - | Review, | Var, | NA |
| 1652- | CA, | Caffeic Acid and Diseases—Mechanisms of Action |
| - | Review, | Var, | NA |
| - | in-vitro, | Cerv, | SiHa |
| 1646- | CA, | Caffeic acid: a brief overview of its presence, metabolism, and bioactivity |
| - | Review, | Nor, | NA |
| 1650- | CA, | Adjuvant Properties of Caffeic Acid in Cancer Treatment |
| - | Review, | Var, | NA |
| 1297- | CA, | Caffeic Acid Phenethyl Ester (CAPE) Induced Apoptosis in Serous Ovarian Cancer OV7 Cells by Deregulation of BCL2/BAX Genes |
| - | in-vitro, | Ovarian, | OV7 |
| 5752- | CA, | Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma |
| - | Review, | HCC, | NA |
| 5756- | CA, | Experimental Evidence of Caffeic Acid’s Neuroprotective Activity in Alzheimer’s Disease: In Vitro, In Vivo, and Delivery-Based Insights |
| - | vitro+vivo, | AD, | NA |
| 5755- | CA, | Caffeic Acid as a Promising Natural Feed Additive: Advancing Sustainable Aquaculture |
| - | Review, | Nor, | NA |
| 5753- | CA, | QC, | MEL, | Effects of Caffeic Acid and Quercetin on In Vitro Permeability, Metabolism and In Vivo Pharmacokinetics of Melatonin in Rats: Potential for Herb-Drug Interaction |
| - | in-vivo, | Colon, | Caco-2 |
| 5751- | CA, | Potential Therapeutic Implications of Caffeic Acid in Cancer Signaling: Past, Present, and Future |
| - | Review, | Var, | NA |
| 5750- | CA, | Exploration of the anticancer properties of Caffeic Acid in malignant mesothelioma cells |
| - | in-vitro, | MM, | NA |
| 5748- | CA, | Prooxidant DNA breakage induced by caffeic acid in human peripheral lymphocytes: involvement of endogenous copper and a putative mechanism for anticancer properties |
| - | in-vitro, | Var, | NA |
| 5747- | CA, | Caffeic Acid Enhances Anticancer Drug-induced Apoptosis in Acid-adapted HCT116 Colon Cancer Cells |
| - | in-vitro, | CRC, | NA |
| 5746- | CA, | Caffeic acid hinders the proliferation and migration through inhibition of IL-6 mediated JAK-STAT-3 signaling axis in human prostate cancer |
| - | in-vitro, | Pca, | PC3 | - | in-vitro, | Pca, | LNCaP |
| 5749- | CA, | Z, | Rad, | Antitumor and Radiosensitizing Effects of Zinc Oxide-Caffeic Acid Nanoparticles against Solid Ehrlich Carcinoma in Female Mice |
| - | vitro+vivo, | BC, | MCF-7 | - | NA, | Liver, | HepG2 |
| 5877- | CA, | Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells |
| - | in-vitro, | CRC, | HCT116 |
| - | vitro+vivo, | Stroke, | PC12 |
| 5865- | CA, | Absorption, distribution and elimination of carnosic acid, a natural antioxidant from Rosmarinus officinalis, in rats |
| - | in-vivo, | Nor, | NA |
| 5866- | CA, | Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Colon, | SW480 | - | in-vitro, | Colon, | HT29 |
| 5867- | CA, | Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines |
| - | in-vitro, | Pca, | DU145 | - | in-vitro, | Liver, | Hep3B | - | in-vitro, | AML, | K562 | - | in-vitro, | Pca, | PC3 | - | in-vitro, | BC, | MDA-MB-231 |
| 5868- | CA, | Carnosic acid inhibits the proliferation and migration capacity of human colorectal cancer cells |
| - | in-vitro, | Colon, | Caco-2 | - | in-vitro, | Colon, | HT29 | - | in-vitro, | CRC, | LoVo |
| 5869- | CA, | Carnosic Acid Induces Antiproliferation and Anti-Metastatic Property of Esophageal Cancer Cells via MAPK Signaling Pathways |
| - | in-vitro, | ESCC, | KYSE150 |
| 5870- | CA, | Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen‐Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells |
| - | vitro+vivo, | BC, | T47D | - | in-vitro, | BC, | MCF-7 |
| 5871- | CA, | Carnosic Acid Attenuates an Early Increase in ROS Levels during Adipocyte Differentiation by Suppressing Translation of Nox4 and Inducing Translation of Antioxidant Enzymes |
| - | in-vitro, | Nor, | NA |
| 5876- | CA, | Carnosic acid, a rosemary phenolic compound, induces apoptosis through reactive oxygen species-mediated p38 activation in human neuroblastoma IMR-32 cells |
| - | in-vitro, | neuroblastoma, | NA |
| 5875- | CA, | Carnosic acid prevents dextran sulfate sodium-induced acute colitis associated with the regulation of the Keap1/Nrf2 pathway |
| - | in-vivo, | IBD, | NA |
| 5874- | CA, | Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen-Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells |
| - | vitro+vivo, | BC, | T47D | - | in-vitro, | BC, | MCF10 |
| 5774- | CA, | CAPE, | Caffeic Acid Versus Caffeic Acid Phenethyl Ester in the Treatment of Breast Cancer MCF-7 Cells: Migration Rate Inhibition |
| - | NA, | BC, | MCF-7 |
| 5872- | CA, | Nrf2/ARE-Mediated Antioxidant Actions of Pro-Electrophilic Drugs |
| - | Review, | Nor, | NA |
| 5873- | CA, | Carnosic acid serves as a dual Nrf2 activator and PTEN/AKT suppressor to inhibit traumatic heterotopic ossification |
| - | vitro+vivo, | Nor, | NA |
| 5924- | CA, | Carnosic acid impedes cell growth and enhances anticancer effects of carmustine and lomustine in melanoma |
| - | vitro+vivo, | Melanoma, | B16-F10 |
| 5923- | CA, | RosA, | Rosemary as a Potential Source of Natural Antioxidants and Anticancer Agents: A Molecular Docking Study |
| - | Review, | Var, | NA |
| 4268- | Caff, | Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects |
| - | Study, | NA, | NA |
| 4267- | Caff, | Caffeine‐mediated BDNF release regulates long‐term synaptic plasticity through activation of IRS2 signaling |
| - | in-vivo, | NA, | NA |
| 1206- | Caff, | Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices |
| - | in-vitro, | NA, | NA | - | ex-vivo, | NA, | NA |
| 1205- | Caff, | immuno, | Caffeine-enhanced anti-tumor activity of anti-PD1 monoclonal antibody |
| - | in-vivo, | Melanoma, | B16-F10 |
| 1653- | Caff, | Higher Caffeinated Coffee Intake Is Associated with Reduced Malignant Melanoma Risk: A Meta-Analysis Study |
| - | Review, | Melanoma, | NA |
| 4161- | Caff, | Chronic caffeine prevents changes in inhibitory avoidance memory and hippocampal BDNF immunocontent in middle-aged rats |
| - | in-vivo, | AD, | NA |
| 5778- | Calc, | VitD3, | Colorectal cancer risk and dietary intake of calcium, vitamin D, and dairy products: a meta-analysis of 26,335 cases from 60 observational studies |
| - | Study, | CRC, | NA |
| 5777- | Calc, | Calcium intake and colorectal cancer risk: dose-response meta-analysis of prospective observational studies |
| - | Study, | CRC, | NA |
| 5775- | Calc, | Calcium Intake and Risk of Colorectal Cancer in the NIH-AARP Diet and Health Study |
| - | Study, | CRC, | NA |
| 5776- | Calc, | Calcium |
| - | Review, | Var, | NA |
| 5779- | Calc, | Calcium supplementation for the prevention of colorectal adenomas: A systematic review and meta-analysis of randomized controlled trials |
| - | Study, | CRC, | NA |
| 5842- | CAP, | Capsaicin: Current Understanding of Its Mechanisms and Therapy of Pain and Other Pre-Clinical and Clinical Uses |
| - | Review, | Nor, | NA | - | Review, | Diabetic, | NA |
| 5841- | CAP, | The red pepper’s spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ |
| - | in-vitro, | HCC, | HepG2 |
| 5840- | CAP, | Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory network |
| - | Review, | Var, | NA |
| 5839- | CAP, | Capsaicin: beyond TRPV1 |
| - | Review, | Var, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid