Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
6548- BSB,    Anticancer effects of α-Bisabolol in human non-small cell lung carcinoma cells are mediated via apoptosis induction, cell cycle arrest, inhibition of cell migration and invasion and upregulation of P13K/AKT signalling pathway
- in-vitro, NSCLC, A549
AntiCan↑, Dose↝, TumCCA↑, mt-Apoptosis↑, TumCMig↓, PI3K↓, Akt↓,
6551- BSB,    α-bisabolol β-d-fucopyranoside (ABFP) ameliorates scopolamine-induced memory deficits through cholinesterase inhibition and attenuation of oxidative stress in zebrafish (Danio rerio)
- in-vivo, AD, NA
*ROS↓, *AChE↓,
6550- BSB,    α-bisabolol β-D-fucopyranoside as a potential modulator of β-amyloid peptide induced neurotoxicity: An in vitro &in silico study
- in-vivo, AD, NA
*AChE↓, *antiOx↓, *neuroP↑,
6547- BSB,    Antitumor effects of a-bisabolol against pancreatic cancer
- vitro+vivo, PC, PANC1 - in-vitro, PC, MIA PaCa-2 - in-vitro, PC, KLM1 - in-vitro, PC, KP4 - in-vitro, Nor, ACBRI515
TumCP↓, selectivity↑, Apoptosis↑, Akt↓, EGR1↑, TumCG↓, Dose↝, PI3K↓, PDK1↓, mTORC2↑,
6542- BSB,    Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
- Review, Var, NA - Review, Park, NA - Review, AD, NA
AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL6↑, *MMP13↓,
6543- BSB,    alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells
- in-vitro, GBM, U87MG
tumCV↓, selectivity↑, TumCD↑, Apoptosis↑, MOMP↓, Cyt‑c↑, cl‑PARP↑,
6544- BSB,    Involvement of mitochondrial permeability transition pore opening in alpha-bisabolol induced apoptosis
- in-vitro, GBM, NA
*Inflam↓, *AntiBio↑, selectivity↑, Apoptosis↑, Casp3↑, cl‑PARP↑, MMP↓, Cyt‑c↑, MPT↑, ROS↑, eff↓, OCR↓, eff↑,
6545- BSB,    The antineoplastic agent α-bisabolol promotes cell death by inducing pores in mitochondria and lysosomes
MPT↑, Casp↑, TumAuto↑, Apoptosis↑, TumCD↑, Dose↝, MMP↓, ROS↑, mtDam↑,
6546- BSB,    α-Bisabolol Inhibits Invasiveness and Motility in Pancreatic Cancer Through KISS1R Activation
- in-vitro, PC, NA
Apoptosis↑, TumCI↓, KISS1↑,
6552- BSB,    Biochemical characterization of chamomile essential oil: Antioxidant, antibacterial, anticancer and neuroprotective activity and potential treatment for Alzheimer's disease
- in-vivo, AD, NA
*TNF-α↓, *Aβ↓, *Casp3↓, *Bcl-2↓, *neuroP↑, *antiOx↑, *Inflam↓, *AntiBio↑, *AChE↓, *BChE↓, Dose↝, Dose↝, Dose↝,
6553- BSB,    Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms
- Review, Nor, NA
*ROS↓, *Inflam↓, *Inf↓, *neuroP↑, *RNS↓, *MDA↓, *GSH↑, *MPO↓, *SOD↑, *Catalase↑, *Bcl-2↑, *BAX↓, *P53↓, *APAF1↓, *Casp3↓, *Casp9↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2↓, *ERK↓, *JNK↓, *NF-kB↓, *p38↓, *cognitive↑, *BChE↓,
6554- BSB,  doxoR,    α-Bisabolol: A Dietary Sesquiterpene that Attenuates Apoptotic and Nonapoptotic Cell Death Pathways by Regulating the Mitochondrial Biogenesis and Endoplasmic Reticulum Stress–Hippo Signaling Axis in Doxorubicin-Induced Acute Cardiotoxicity in Rats
- in-vivo, Nor, NA
*cardioP↑, *chemoP↑, *antiOx↑, *ROS↓, *toxicity↓, *DNAdam↓, *lipid-P↓, *ER Stress↓,
6555- BSB,    Cyclodextrin Conjugated α-Bisabolol Suppresses FAK Phosphorylation and Induces Apoptosis in Pancreatic Cancer
- vitro+vivo, PC, NA
TumCP↓, TumCI↓, p‑FAK↓, TumVol↓, Ki-67↓,
6556- BSB,    A Comprehensive Study of Therapeutic Applications of Chamomile
- Review, Nor, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiBio↑, *hepatoP↑, *AntiCan↑, *other↝, *toxicity↓, *Wound Healing↓, *Dose↝, *Dose↝, *eff↝, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *AST↓, *ALAT↓,
6557- BSB,    Alpha-bisabolol protects against neonatal asthma by suppressing airway inflammatory signaling
- in-vivo, Nor, NA
*ROS↓, *Inflam↓, *IL1β↓, *IL6↓, *IL8↓, *IL17↓, *CXCR4↓, *COX2↓, *TLR4↓, *NO↓, *MDA↓, *XO↓,
6558- BSB,    Involvement of mitochondrial permeability transition pore opening in α-bisabolol induced apoptosis
OCR↓, MPT↑, selectivity↑, ROS↑, eff↓, *ROS∅, cl‑PARP↑, MMP↓, eff↑,
6559- BSB,    Modulatory effect of α-Bisabolol on induced apoptosis via mitochondrial and NF-κB/Akt/PI3K Signaling pathways in MCF-7 breast cancer cells
- in-vitro, BC, MCF7
TumCG↓, TumCP↓, Apoptosis↓, ROS↑, Bcl-2↓, BAX↑, BAD↑, Casp3↑, Casp9↑, Cyt‑c↑, NF-kB↓, p‑PI3K↓, p‑Akt↓,
6560- BSB,  doxoR,    Α-Bisabolol, a Component of German Chamomile Tea Attenuates NLRP3 Inflammasome Mediated Pyroptosis, NF-ΚB/MAPK Signaling Activation and Apoptosis by Invoking NRF2 Mediated Antioxidant Defense Systems in Doxorubicin-Induced Liver Injury in Rats
- in-vivo, Nor, NA
*lipid-P↓, *antiOx↑, *Apoptosis↓, *Inflam↓,
5674- BTZ,    Bortezomib-induced unfolded protein response increases oncolytic HSV-1 replication resulting in synergistic, anti-tumor effects
- in-vivo, GBM, NA - in-vivo, HNSCC, NA
ER Stress↑, GRP78/BiP↑, CHOP/DDIT3↑, PERK↑, IRE1↑, UPR↑, HSP70/HSPA5↑, HSP90↑, eff↑,
5745- Buty,    Microbial Oncotarget: Bacterial-Produced Butyrate, Chemoprevention and Warburg Effect
- Review, Var, NA
selectivity↑, HDAC↓, TumCP↓, Apoptosis↑, Warburg↓, chemoPv↑,
5744- Buty,  PacT,    Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction
- in-vivo, Var, NA
chemoP↑, neuroP↑, Inflam↓, GutMicro↑, *ROS↓, Dose↝,
5743- Buty,    Regulation of Intestinal Butyrate Transporters by Oxidative and Inflammatory Status
- Review, Var, NA
*GutMicro↑, *other↑, *Inflam↓, *ROS↓, AntiCan↑, HCAR2↑, HDAC↓,
5742- Buty,    Butyrate: A Double-Edged Sword for Health?
- Review, Var, NA
HCAR2↑, Inflam↓, HDAC↓, *IFN-γ↓, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL10↑, *LTA/TNF-β↑, *NF-kB↓, *ROS↓, PPARγ↓, Weight↓,
5741- Buty,  Rad,    Microencapsulated Sodium Butyrate in the Prevention of Acute Radiotherapy Proctitis: Single-Center Prospective Study
- in-vivo, Pca, NA
Dose↝, radioP↑, Pain↓,
5740- Buty,    A Review of Nutritional Regulation of Intestinal Butyrate Synthesis: Interactions Between Dietary Polysaccharides and Proteins
- Review, RCC, NA
*eff↓, Dose↝, eff↑, HDAC↓, ac‑H3↓, ac‑H4↓, *HCAR2↑, *Inflam↓, *ROS↓, *NRF2↑, *GSH↑, *CLDN1↑, *ZO-1↑, IL1β↓, IL6↓, COX2↓, eff↝, eff↑, other↝,
5739- Buty,    Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)
- Review, Var, NA
GutMicro↑, *Inflam↓, *IL6↓, *TNF-α↓, *IL17↓, *IL10↑, *ROS↝, COX2↓, NLRP3↓, Imm↑, HDAC↓, TumCCA↑, Apoptosis↑, ROS↑, Casp↑, mtDam↑, Cyt‑c↑, eff↑, chemoP↑, ChemoSen↑, eff↑, RadioS↑, HCAR2↑,
5736- Buty,    Clinical and pharmacologic study of tributyrin: an oral butyrate prodrug
- Trial, Var, NA
Dose↝, BioAv↝, toxicity↓, OS↝,
5738- Buty,    Butyrate’s role in human health and the current progress towards its clinical application to treat gastrointestinal disease
- Review, Nor, NA
*GutMicro↑, *Risk↓,
5735- Buty,    Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease
- Study, Nor, NA
*Inflam↓, GutMicro↑, Imm↑,
5734- Buty,    Enhanced production of IL-18 in butyrate-treated intestinal epithelium by stimulation of the proximal promoter region
- vitro+vivo, Nor, NA
*IL18↑,
5733- Buty,  VitB3,    Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- in-vivo, CRC, NA
GutMicro↑, HCAR2↑, AntiCan↑, Inflam↓, IL18↑,
5732- Buty,    GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon
- Study, CRC, NA
HCAR2↑, other↓, Apoptosis↑, HDAC↓, Bcl-2↓, Bcl-xL↓, cycD1/CCND1↓, DR5↑, NF-kB↓, GutMicro↑, SLC12A5↝,
5731- Buty,    The Warburg Effect Dictates the Mechanism of Butyrate Mediated Histone Acetylation and Cell Proliferation
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29
HDAC↓, Warburg↓, TumCP⇅, HATs↑, BioAv↓, other↝, Risk↓,
5737- Buty,    Butyrate Suppresses the Proliferation of Colorectal Cancer Cells via Targeting Pyruvate Kinase M2 and Metabolic Reprogramming
- in-vitro, CRC, HCT116
HDAC↓, TumCP↓, PKM2↑, Warburg↓,
1080- Buty,    Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition
- in-vitro, CRC, HT-29
HDAC↓, TNF-α↓, COX2↓,
1032- Buty,    Gut microbiome-derived butyrate inhibits the immunosuppressive factors PD-L1 and IL-10 in tumor-associated macrophages in gastric cancer
- in-vivo, GC, AGS
GutMicro↑, PD-L1↓, IL10↓, TumCG↓,
2050- Buty,    The Role of Sodium Phenylbutyrate in Modifying the Methylome of Breast Cancer Cells
- in-vitro, BC, MCF7
eff↑, HDAC↓, TumCG↓,
2047- Buty,    Sodium butyrate inhibits migration and induces AMPK-mTOR pathway-dependent autophagy and ROS-mediated apoptosis via the miR-139-5p/Bmi-1 axis in human bladder cancer cells
- in-vitro, CRC, T24/HTB-9 - in-vitro, Nor, SV-HUC-1 - in-vitro, Bladder, 5637 - in-vivo, NA, NA
HDAC↓, AntiTum↑, TumCMig↓, AMPK↑, mTOR↑, TumAuto↑, ROS↑, miR-139-5p↑, BMI1↓, TumCI?, E-cadherin↑, N-cadherin↓, Vim↓, Snail↓, cl‑PARP↑, cl‑Casp3↑, BAX↑, Bcl-2↓, Bcl-xL↓, MMP↓, PINK1↑, PARK2↑, TumMeta↓, TumCG↓, LC3II↑, p62↓, eff↓,
1224- Buty,    Intratumor microbiome-derived butyrate promotes lung cancer metastasis
- in-vivo, Lung, NA
TumCG↑, H19↑, HDAC2↓,
1230- CA,  Caff,    Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - Human, NA, NA
TumVol↓, TumCG↓, ER(estro)↓, cycD1/CCND1↓, IGF-1R↓, p‑Akt↓,
1207- CA,  PacT,    Caffeine inhibits the anticancer activity of paclitaxel via down-regulation of α-tubulin acetylation
- in-vitro, Lung, A549 - in-vitro, Cerv, HeLa
TumCG↑, TumCMig↓, Apoptosis↓, ac‑α-tubulin↑,
1651- CA,  PBG,    Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer
- Review, Var, NA
Apoptosis↑, TumCCA↓, TumCMig↓, TumMeta↓, ChemoSen↑, eff↑, eff↑, eff↓, eff↝, Dose∅, AMPK↑, p62↓, LC3II↑, Ca+2↑, Bax:Bcl2↑, CDK4↑, CDK6↑, RB1↑, EMT↓, E-cadherin↑, Vim↓, β-catenin/ZEB1↓, NF-kB↓, angioG↑, VEGF↓, TSP-1↑, MMP9↓, MMP2↓, ChemoSen↑, eff↑, ROS↑, CSCs↓, Fas↑, P53↑, BAX↑, Casp↑, β-catenin/ZEB1↓, NDRG1↑, STAT3↓, MAPK↑, ERK↑, eff↑, eff↑, eff↑,
1652- CA,    Caffeic Acid and Diseases—Mechanisms of Action
- Review, Var, NA
Dose∅, ROS⇅, NF-kB↓, STAT3↓, VEGF↓, MMP9↓, HSP70/HSPA5↑, AST↝, ALAT↝, ALP↝, Hif1a↓, IL6↓, IGF-1R↓, P21↑, iNOS↓, ERK↓, Snail↓, BID↑, BAX↑, Casp3↑, Casp7↑, Casp9↑, cycD1/CCND1↓, Vim↓, β-catenin/ZEB1↓, COX2↓, ROS↑,
1640- CA,  MET,    Caffeic Acid Targets AMPK Signaling and Regulates Tricarboxylic Acid Cycle Anaplerosis while Metformin Downregulates HIF-1α-Induced Glycolytic Enzymes in Human Cervical Squamous Cell Carcinoma Lines
- in-vitro, Cerv, SiHa
GLS↓, NADPH↓, ROS↑, TumCD↑, AMPK↑, Hif1a↓, GLUT1↓, GLUT3↓, HK2↓, PFK↓, PKM2↓, LDH↓, cMyc↓, BAX↓, cycD1/CCND1↓, PDH↓, ROS↑, Apoptosis↑, eff↑, ACLY↓, FASN↓, Bcl-2↓, Glycolysis↓,
1646- CA,    Caffeic acid: a brief overview of its presence, metabolism, and bioactivity
- Review, Nor, NA
*BioAv↓, ROS⇅, selectivity↑, other∅, VEGF↓, MMP2↓, MMP9↓,
1650- CA,    Adjuvant Properties of Caffeic Acid in Cancer Treatment
- Review, Var, NA
ROS↑, antiOx↑, Inflam↓, AntiCan↑, NF-kB↓, STAT3↓, ERK↓, ChemoSen↑, RadioS↑, AMPK↑, eff↑, selectivity↑, COX2↓, Dose∅, PHDs↓, MMP9↓, MMP2↓, Dose∅, Dose∅, Ca+2↑, Dose?, MMP↓, RadioS↑,
1297- CA,    Caffeic Acid Phenethyl Ester (CAPE) Induced Apoptosis in Serous Ovarian Cancer OV7 Cells by Deregulation of BCL2/BAX Genes
- in-vitro, Ovarian, OV7
lysosome↓, Apoptosis↑, Bax:Bcl2↑,
3032- CA,    Carnosic Acid Induces Apoptosis Through Reactive Oxygen Species-mediated Endoplasmic Reticulum Stress Induction in Human Renal Carcinoma Caki Cells
- in-vitro, Kidney, Caki-1
cl‑PARP↑, ROS↑, ER Stress↑, ATF4↑, CHOP/DDIT3↑, selectivity↑,
2399- CA,  EA,    Polyphenol-rich diet mediates interplay between macrophage-neutrophil and gut microbiota to alleviate intestinal inflammation
- Review, Col, NA
eff↝, eff↑, Weight↑,
3758- CA,  RT,  CGA,    Polyphenols and inhibitory effects of crude and purified extracts from tomato varieties on the formation of advanced glycation end products and the activity of angiotensin-converting and acetylcholinesterase enzymes
- Analysis, AD, NA
*AChE↓, *eff↑,

Showing Research Papers: 1751 to 1800 of 7372
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7372

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   PARK2↑, 1,   ROS↑, 12,   ROS⇅, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 5,   MPT↑, 3,   mtDam↑, 2,   OCR↓, 2,   PINK1↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACLY↓, 1,   ALAT↝, 1,   AMPK↑, 4,   cMyc↓, 1,   FASN↓, 1,   GLS↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   LDH↓, 1,   NADPH↓, 1,   PDH↓, 1,   PDK1↓, 1,   PFK↓, 1,   PKM2↓, 1,   PKM2↑, 1,   PPARγ↓, 1,   Warburg↓, 3,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   p‑Akt↓, 2,   Apoptosis↓, 2,   Apoptosis↑, 12,   mt-Apoptosis↑, 1,   BAD↑, 1,   Bak↓, 1,   BAX↓, 1,   BAX↑, 5,   Bax:Bcl2↑, 2,   Bcl-2↓, 5,   Bcl-xL↓, 2,   BID↑, 2,   Casp↑, 3,   Casp3↑, 4,   cl‑Casp3↑, 1,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 3,   Cyt‑c↑, 5,   DR5↑, 1,   Fas↑, 2,   iNOS↓, 1,   MAPK↑, 1,   MOMP↓, 1,   TumCD↑, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 5,   HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

H19↑, 1,   ac‑H3↓, 1,   ac‑H4↓, 1,   HATs↑, 1,   KISS1↑, 1,   other↓, 1,   other↝, 2,   other∅, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 2,   ER Stress↑, 2,   GRP78/BiP↑, 1,   HSP70/HSPA5↑, 2,   HSP90↑, 1,   IRE1↑, 1,   PERK↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3II↑, 2,   lysosome↓, 1,   p62↓, 2,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 2,   PARP↑, 1,   cl‑PARP↑, 5,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↑, 1,   cycD1/CCND1↓, 4,   P21↑, 1,   RB1↑, 1,   TumCCA↓, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMI1↓, 1,   CSCs↓, 1,   EMT↓, 1,   ERK↓, 2,   ERK↑, 1,   FGF↓, 1,   HDAC↓, 11,   HDAC2↓, 1,   IGF-1R↓, 2,   mTOR↑, 1,   mTORC2↑, 1,   PI3K↓, 2,   p‑PI3K↓, 1,   STAT3↓, 3,   TumCG↓, 6,   TumCG↑, 2,  

Migration(tgid=13) ⓘ

Ca+2↑, 2,   CEA↓, 1,   E-cadherin↑, 2,   p‑FAK↓, 1,   Ki-67↓, 1,   miR-139-5p↑, 1,   MMP2↓, 3,   MMP9↓, 4,   N-cadherin↓, 1,   Snail↓, 2,   TIMP2↑, 1,   TSP-1↑, 1,   TumCI?, 1,   TumCI↓, 2,   TumCMig↓, 4,   TumCP↓, 5,   TumCP⇅, 1,   TumMeta↓, 2,   Vim↓, 3,   ac‑α-tubulin↑, 1,   β-catenin/ZEB1↓, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   ATF4↑, 1,   EGFR↑, 1,   EGR1↑, 1,   Hif1a↓, 2,   PHDs↓, 1,   VEGF↓, 3,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   GLUT3↓, 1,   SLC12A5↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 6,   HCAR2↑, 5,   IL10↓, 1,   IL18↑, 1,   IL1β↓, 1,   IL6↓, 2,   Imm↑, 2,   Inflam↓, 4,   NF-kB↓, 5,   NF-kB↑, 1,   PD-L1↓, 1,   TNF-α↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↑, 1,   ER(estro)↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↝, 1,   ChemoSen↑, 4,   Dose?, 1,   Dose↝, 10,   Dose∅, 5,   eff↓, 4,   eff↑, 17,   eff↝, 3,   RadioS↑, 4,   selectivity↑, 8,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↝, 1,   ALP↝, 1,   AST↝, 1,   CEA↓, 1,   EGFR↑, 1,   GutMicro↑, 6,   HER2/EBBR2↓, 1,   IL6↓, 2,   Ki-67↓, 1,   LDH↓, 1,   PD-L1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 5,   AntiTum↑, 1,   chemoP↑, 2,   chemoPv↑, 1,   NDRG1↑, 1,   neuroP↑, 1,   OS↝, 1,   Pain↓, 1,   radioP↑, 1,   Risk↓, 1,   toxicity↓, 1,   TumVol↓, 2,   Weight↓, 1,   Weight↑, 1,  
Total Targets: 183

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 5,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 5,   Catalase↑, 3,   GSH↑, 4,   Keap1↑, 1,   lipid-P↓, 3,   MDA↓, 3,   MPO↓, 1,   NRF2↑, 1,   RNS↓, 1,   ROS↓, 10,   ROS↝, 1,   ROS∅, 1,   SOD↑, 3,   TBARS↓, 1,   uricA↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Cell Death(tgid=5) ⓘ

APAF1↓, 1,   Apoptosis↓, 2,   BAX↓, 2,   Bcl-2↓, 1,   Bcl-2↑, 2,   Casp3↓, 3,   Casp9↓, 1,   Cyt‑c↓, 1,   iNOS↓, 3,   JNK↓, 1,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,   other↝, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   P53↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 1,  

Migration(tgid=13) ⓘ

CLDN1↑, 1,   MMP13↓, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GastroP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX2↓, 4,   CXCR4↓, 1,   HCAR2↑, 1,   IFN-γ↓, 1,   IL10↑, 2,   IL17↓, 2,   IL18↑, 1,   IL1β↓, 4,   IL6↓, 6,   IL6↑, 1,   IL8↓, 2,   Imm↑, 1,   Inflam↓, 11,   LTA/TNF-β↑, 1,   NF-kB↓, 2,   TLR4↓, 1,   TNF-α↓, 7,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 5,   BChE↓, 3,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,   BACE↓, 1,   XO↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 2,   Dose↝, 2,   eff↓, 1,   eff↑, 2,   eff↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   creat↓, 1,   GutMicro↑, 2,   IL6↓, 6,   IL6↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   cardioP↑, 3,   chemoP↑, 1,   cognitive↑, 1,   hepatoP↑, 1,   motorD↑, 1,   neuroP↑, 4,   Pain↓, 1,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 3,   Wound Healing↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   CD8+↑, 1,   Inf↓, 1,  
Total Targets: 94

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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