| 5838- | CAP, | Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway |
| - | in-vitro, | NPC, | NA |
| 5837- | CAP, | Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression |
| - | in-vitro, | lymphoma, | PEL |
| 5836- | CAP, | In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway |
| - | vitro+vivo, | PC, | AsPC-1 | - | in-vitro, | PC, | Bxpc-3 |
| 5835- | CAP, | Capsaicin and dihydrocapsaicin induce apoptosis in human glioma cells via ROS and Ca2+-mediated mitochondrial pathway |
| - | in-vitro, | GBM, | U251 |
| 5834- | CAP, | Capsaicin and TRPV1: A Novel Therapeutic Approach to Mitigate Vascular Aging |
| - | Study, | Nor, | NA |
| 5833- | CAP, | Capsaicin: From Plants to a Cancer-Suppressing Agent |
| - | Review, | Var, | NA |
| 5832- | CAP, | Capsaicin induces cell cycle arrest and apoptosis in human KB cancer cells |
| - | in-vitro, | Oral, | KB |
| 5831- | CAP, | Unraveling TRPV1’s Role in Cancer: Expression, Modulation, and Therapeutic Opportunities with Capsaicin |
| 5830- | CAP, | Inhibition of pyroptosis and apoptosis by capsaicin protects against LPS-induced acute kidney injury through TRPV1/UCP2 axis in vitro |
| - | in-vitro, | Nor, | HK-2 |
| 5825- | CAP, | Bioavailability of capsaicin and its implications for drug delivery |
| - | Review, | Var, | NA | - | Review, | Arthritis, | NA | - | Review, | Obesity, | NA |
| 5829- | CAP, | Anti-cancer activity of capsaicin and its analogs in gynecological cancers |
| - | Review, | Var, | NA |
| 5828- | CAP, | Capsaicin: a novel radio-sensitizing agent for prostate cancer |
| - | vitro+vivo, | Pca, | LNCaP | - | in-vitro, | Pca, | DU145 | - | in-vitro, | Pca, | PC3 |
| 5827- | CAP, | The Effect of Topical Capsaicin 8% on Pain in Chemotherapy-induced Peripheral Neuropathy |
| - | Trial, | Var, | NA |
| 5826- | CAP, | Capsaicin induces mitochondrial dysfunction and apoptosis in anaplastic thyroid carcinoma cells via TRPV1-mediated mitochondrial calcium overload |
| - | in-vitro, | Thyroid, | NA |
| 5824- | CAP, | Pharmacokinetic and the effect of capsaicin in Capsicum frutescens on decreasing plasma glucose level |
| - | Study, | Diabetic, | NA |
| 5844- | CAP, | Non-pungent long chain capsaicin-analogs arvanil and olvanil display better anti-invasive activity than capsaicin in human small cell lung cancers |
| - | in-vitro, | Lung, | DMS114 |
| 5861- | CAP, | Anticancer Properties of Capsaicin Against Human Cancer |
| - | Review, | Var, | NA |
| 5860- | CAP, | Beneficial Effects of Capsaicin in Disorders of the Central Nervous System |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | Stroke, | NA |
| 5859- | CAP, | Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain? |
| - | Review, | Var, | NA |
| 5858- | CAP, | Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health |
| - | Review, | Nor, | NA | - | Review, | AD, | NA |
| 5856- | CAP, | Potential of capsaicin as a combinatorial agent to overcome chemoresistance and to improve outcomes of cancer therapy |
| - | Review, | Var, | NA |
| 5855- | CAP, | Unravelling the Mystery of Capsaicin: A Tool to Understand and Treat Pain |
| - | in-vivo, | Nor, | NA |
| 5854- | CAP, | Pharmacological activity of capsaicin: Mechanisms and controversies (Review) |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 5853- | CAP, | Pharmacokinetic analysis of capsaicin after topical administration of a high-concentration capsaicin patch to patients with peripheral neuropathic pain |
| - | Review, | Var, | NA |
| 5852- | CAP, | Capsaicin Synergizes with Camptothecin to Induce Increased Apoptosis in Human Small Cell Lung Cancers via the Calpain Pathway |
| - | vitro+vivo, | NSCLC, | NA |
| 5851- | CAP, | Capsaicin Potentiates Anticancer Drug Efficacy Through Autophagy-Mediated Ribophorin II Downregulation and Necroptosis in Oral Squamous Cell Carcinoma Cells |
| - | in-vitro, | Oral, | NA |
| 5850- | CAP, | Anticancer Activity of Natural and Synthetic Capsaicin Analogs |
| - | Review, | Var, | NA |
| 5849- | CAP, | The Impact of TRPV1 on Cancer Pathogenesis and Therapy: A Systematic Review |
| - | Review, | Var, | NA |
| 5848- | CAP, | SRF, | Capsaicin exerts synergistic antitumor effect with sorafenib in hepatocellular carcinoma cells through AMPK activation |
| - | in-vitro, | HCC, | HepG2 | - | in-vitro, | HCC, | HUH7 |
| 5847- | CAP, | An updated review on molecular mechanisms underlying the anticancer effects of capsaicin |
| - | in-vitro, | Liver, | HepG2 |
| 5846- | CAP, | Capsaicin Alters the Expression of Genetic and Epigenetic Molecules In Hepatocellular Carcinoma Cell |
| - | in-vitro, | HCC, | HepG2 |
| 5845- | CAP, | Unveiling the Molecular Mechanisms Driving the Capsaicin-Induced Immunomodulatory Effects on PD-L1 Expression in Bladder and Renal Cancer Cell Lines |
| - | in-vivo, | RCC, | A498 | - | in-vitro, | RCC, | T24/HTB-9 | - | NA, | Bladder, | 5637 |
| 5843- | CAP, | The Effects of Capsaicin on Gastrointestinal Cancers |
| - | Review, | GC, | NA |
| 5212- | CAP, | PI, | Chemo, | Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin |
| - | in-vitro, | Colon, | Caco-2 |
| 5204- | CAP, | Low-concentration capsaicin promotes colorectal cancer metastasis by triggering ROS production and modulating Akt/mTOR and STAT-3 pathways |
| - | in-vitro, | Colon, | SW480 | - | in-vitro, | Colon, | CT26 |
| 5203- | CAP, | Capsaicin Promotes Apoptosis and Inhibits Cell Migration via the Tumor Necrosis Factor-Alpha (TNFα) and Nuclear Factor Kappa B (NFκB) Signaling Pathway in Oral Cancer Cells |
| - | in-vitro, | OS, | KB |
| 5202- | CAP, | Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways |
| - | vitro+vivo, | Bladder, | 5637 | - | in-vitro, | Bladder, | T24/HTB-9 |
| 5201- | CAP, | Inhibiting ROS-STAT3-dependent autophagy enhanced capsaicin-induced apoptosis in human hepatocellular carcinoma cells |
| - | NA, | HCC, | HepG2 |
| 5198- | CAP, | Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines |
| - | in-vitro, | CRC, | LoVo | - | in-vitro, | CRC, | Colo320 |
| 5199- | CAP, | Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation |
| - | vitro+vivo, | AML, | NA |
| 5200- | CAP, | Capsaicin Induces Apoptosis in Human Small Cell Lung Cancer via the TRPV6 Receptor and the Calpain Pathway |
| - | in-vitro, | Lung, | NA |
| 3854- | CAP, | Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice |
| - | in-vivo, | AD, | NA |
| 3855- | CAP, | Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice |
| - | in-vivo, | AD, | NA |
| 2394- | CAP, | Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction |
| - | in-vitro, | Nor, | GES-1 |
| 2347- | CAP, | Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis |
| - | in-vivo, | Nor, | NA | - | in-vitro, | Nor, | RAW264.7 |
| 2348- | CAP, | Recent advances in analysis of capsaicin and its effects on metabolic pathways by mass spectrometry |
| - | Analysis, | Nor, | NA |
| 2349- | CAP, | The TRPV1-PKM2-SREBP1 axis maintains microglial lipid homeostasis in Alzheimer’s disease |
| - | in-vivo, | AD, | NA |
| 2652- | CAP, | Oxidative Stress Inducers in Cancer Therapy: Preclinical and Clinical Evidence |
| - | Review, | Var, | NA |
| 1261- | CAP, | Capsaicin inhibits glycolysis in esophageal squamous cell carcinoma by regulating hexokinase‑2 expression |
| - | in-vitro, | ESCC, | KYSE150 |
| 1263- | CAP, | Capsaicin inhibits the migration and invasion via the AMPK/NF-κB signaling pathway in esophagus sequamous cell carcinoma by decreasing matrix metalloproteinase-9 expression |
| - | in-vitro, | ESCC, | Eca109 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
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